glutamic acid and dextrothyroxine

glutamic acid has been researched along with dextrothyroxine in 44 studies

Research

Studies (44)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's13 (29.55)18.2507
2000's14 (31.82)29.6817
2010's14 (31.82)24.3611
2020's3 (6.82)2.80

Authors

AuthorsStudies
Arena, JP; Cully, DF; Liu, KK; Paress, PS; Schaeffer, JM1
Arena, JP; Cully, DF; Frazier, EG; Liu, KK; Mrozik, H; Paress, PS; Schaeffer, JM1
Arena, JP; Cully, DF; Liu, KK; Paress, PS; Schaeffer, JM; Van der Ploeg, LH; Vassilatis, DK1
Arena, JP; Cully, DF; Etter, A; Liu, KK; Schaeffer, JM1
Martin, RJ1
Arena, JP; Cully, DF; Elliston, KO; Hamelin, M; Paress, PS; Schaeffer, JM; Van der Ploeg, LH; Vassilatis, DK1
Adelsberger, H; Dudel, J; Scheuer, T1
Avery, L; Davis, MW; Dent, JA1
Brownlee, DJ; Holden-Dye, L; Walker, RJ1
Beech, RN; Blackhall, WJ; Pouliot, JF; Prichard, RK1
Arena, JP; Cully, DF; Etter, A; Liu, KK; Reiss, B; Schaeffer, JM; Vassilatis, DK1
Paiement, J; Prichard, RK; Ribeiro, P1
Leger, C; Paiement, JP; Prichard, RK; Ribeiro, P1
Avery, L; Dent, JA; Smith, MM; Vassilatis, DK1
Franks, CJ; Holden-Dye, L; Pemberton, DJ; Walker, RJ1
Cheeseman, CL; Delany, NS; Wolstenholme, AJ; Woods, DJ1
Beech, RN; Forrester, SG; Prichard, RK1
Ayer, MB; Chaudhary, AG; Cully, DF; Dean, DC; Egan, MA; Garcia, ML; Hunt, DC; Ludmerer, SW; Meinke, PT; Smith, MM; Wallace, MA; Warren, VA; Williams, BS; Zheng, Y1
Anderson, DJ; Davidson, N; Lester, HA; McKinney, S; Slimko, EM1
Lester, HA; Li, P; Slimko, EM1
Feng, XP; Hayashi, J; Kinne, L; Njue, AI; Prichard, RK1
Njue, AI; Prichard, RK1
Holden-Dye, L; Walker, RJ1
Buckinx, R; Derst, C; Janssen, D; Rigo, JM; Van den Eynden, J; Van Kerkhove, E1
Armengaud, C; El Hassani, AK; Gauthier, M; Giurfa, M1
McCavera, S; Rogers, AT; Wolstenholme, AJ; Woods, DJ; Yates, DM1
Bush, E; Foreman, R; Holden-Dye, L; Walker, RJ1
Cohen, BN; Frazier, SJ; Lester, HA1
Althoff, T; Banerjee, S; Gouaux, E; Hibbs, RE1
Andrini, O; Cid, LP; Cornejo, I; González-Nilo, FD; Marabolí, V; Niemeyer, MI; Sepúlveda, FV; Teulon, J1
Akamatsu, M; Furutani, S; Ihara, M; Jones, AK; Matsuda, K; Nishino, Y; Sattelle, DB1
Andersson, M; Lindahl, E; Yoluk, Ö1
Black, WC; Foy, BD; Gray, M; Johnson, LB; Kuklinski, W; Meyers, JI; Partin, KM; Snow, CD1
Fuse, T; Kita, T; Nakata, Y; Ozoe, F; Ozoe, Y1
He, L; Wu, Q; Xu, Q; Xu, Z1
Millar, NS; O Reilly, AO; Puinean, AM; Smelt, CLC; Wang, X; Williamson, MS; Wu, Y1
Furutani, S; Hashimoto, A; Hayashi, H; Ihara, M; Kai, K; Matsuda, K; Okuhara, D; Sattelle, DB1
Atif, M; Estrada-Mondragon, A; Keramidas, A; Lynch, JW; Nguyen, B1
Calimet, N; Cecchini, M; Changeux, JP; Malik, S; Martin, NE1
Buckingham, SD; David, JA; Furutani, S; Ihara, M; Lees, K; Matsuda, K; Mellor, IR; Partridge, FA; Patel, R; Sattelle, DB; Warchal, S1
Atif, M; Capon, RJ; Estrada-Mondragon, A; Keramidas, A; Lynch, JW; Salim, AA; Smith, JJ; Xiao, X1
Atif, M; Keramidas, A; Lynch, JW1
Abongwa, M; Choudhary, S; Kashyap, SS; Kulke, D; Mair, GR; Martin, RJ; Robertson, AP; Verma, S1
Cid, LP; Cornejo, I; Cuevas, P; Sepúlveda, FV; Tribiños, F1

Other Studies

44 other study(ies) available for glutamic acid and dextrothyroxine

ArticleYear
Expression of a glutamate-activated chloride current in Xenopus oocytes injected with Caenorhabditis elegans RNA: evidence for modulation by avermectin.
    Brain research. Molecular brain research, 1992, Volume: 15, Issue:3-4

    Topics: Animals; Anthelmintics; Caenorhabditis elegans; Cell Membrane Permeability; Chloride Channels; Chlorides; Glutamates; Glutamic Acid; Ibotenic Acid; Ion Channel Gating; Ivermectin; Membrane Proteins; Microinjections; Oocytes; Poly A; RNA; Xenopus laevis

1992
The mechanism of action of avermectins in Caenorhabditis elegans: correlation between activation of glutamate-sensitive chloride current, membrane binding, and biological activity.
    The Journal of parasitology, 1995, Volume: 81, Issue:2

    Topics: Animals; Anthelmintics; Anti-Bacterial Agents; Caenorhabditis elegans; Chloride Channels; Drug Synergism; Electrophysiology; Glutamic Acid; Ion Channel Gating; Ivermectin; Macrolides; Membrane Potentials

1995
Cloning of an avermectin-sensitive glutamate-gated chloride channel from Caenorhabditis elegans.
    Nature, 1994, Oct-20, Volume: 371, Issue:6499

    Topics: Amino Acid Sequence; Animals; Base Sequence; Caenorhabditis elegans; Cell Membrane Permeability; Cells, Cultured; Chloride Channels; Cloning, Molecular; DNA, Complementary; Electrophysiology; Escherichia coli; Glutamic Acid; Humans; Ion Channel Gating; Ivermectin; Molecular Sequence Data; Oocytes; Sequence Homology, Amino Acid; Xenopus

1994
An amino acid substitution in the pore region of a glutamate-gated chloride channel enables the coupling of ligand binding to channel gating.
    The Journal of biological chemistry, 1996, Jul-05, Volume: 271, Issue:27

    Topics: Amino Acid Sequence; Animals; Binding Sites; Caenorhabditis elegans; Cell Membrane; Chloride Channels; Cloning, Molecular; Drosophila melanogaster; Egtazic Acid; Female; Glutamic Acid; Humans; Ion Channel Gating; Ivermectin; Kinetics; Macromolecular Substances; Membrane Potentials; Molecular Sequence Data; Muscle, Skeletal; Oocytes; Point Mutation; Protein Structure, Secondary; Receptors, Nicotinic; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Xenopus

1996
An electrophysiological preparation of Ascaris suum pharyngeal muscle reveals a glutamate-gated chloride channel sensitive to the avermectin analogue, milbemycin D.
    Parasitology, 1996, Volume: 112 ( Pt 2)

    Topics: Animals; Anthelmintics; Anti-Bacterial Agents; Ascaris suum; Chloride Channels; Chlorides; Drug Synergism; Electric Conductivity; Glutamic Acid; Ion Channel Gating; Ivermectin; Macrolides; Membrane Potentials; Pharyngeal Muscles; Receptors, Glutamate

1996
Evolutionary relationship of the ligand-gated ion channels and the avermectin-sensitive, glutamate-gated chloride channels.
    Journal of molecular evolution, 1997, Volume: 44, Issue:5

    Topics: Animals; Antinematodal Agents; Caenorhabditis elegans; Chloride Channels; Genes, Helminth; Glutamic Acid; Ion Channel Gating; Ivermectin; Ligands; Molecular Sequence Data; Phylogeny; Sequence Alignment; Sequence Analysis, DNA

1997
A patch clamp study of a glutamatergic chloride channel on pharyngeal muscle of the nematode Ascaris suum.
    Neuroscience letters, 1997, Jul-25, Volume: 230, Issue:3

    Topics: Acetylcholine; Animals; Antinematodal Agents; Ascaris suum; Chloride Channel Agonists; Chloride Channels; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Ivermectin; Membrane Potentials; Mouth; Muscles; Patch-Clamp Techniques

1997
avr-15 encodes a chloride channel subunit that mediates inhibitory glutamatergic neurotransmission and ivermectin sensitivity in Caenorhabditis elegans.
    The EMBO journal, 1997, Oct-01, Volume: 16, Issue:19

    Topics: Alternative Splicing; Animals; Antinematodal Agents; Caenorhabditis elegans; Chloride Channels; Glutamic Acid; Iontophoresis; Ivermectin; Molecular Sequence Data; Muscle Relaxation; Pharynx; Synaptic Transmission

1997
Actions of the anthelmintic ivermectin on the pharyngeal muscle of the parasitic nematode, Ascaris suum.
    Parasitology, 1997, Volume: 115 ( Pt 5)

    Topics: Animals; Anthelmintics; Ascaris suum; Dose-Response Relationship, Drug; Drug Interactions; Enteric Nervous System; Feeding Behavior; gamma-Aminobutyric Acid; Glutamic Acid; Ivermectin; Muscle Contraction; Pharyngeal Muscles

1997
Haemonchus contortus: selection at a glutamate-gated chloride channel gene in ivermectin- and moxidectin-selected strains.
    Experimental parasitology, 1998, Volume: 90, Issue:1

    Topics: Amino Acid Sequence; Animals; Anti-Bacterial Agents; Chloride Channels; DNA Primers; Drug Resistance; Gene Frequency; Genes, Helminth; Glutamic Acid; Haemonchus; Ivermectin; Macrolides; Macromolecular Substances; Male; Molecular Sequence Data; Polymerase Chain Reaction; Selection, Genetic; Sequence Alignment; Sequence Homology, Amino Acid; Species Specificity

1998
Picrotoxin blockade of invertebrate glutamate-gated chloride channels: subunit dependence and evidence for binding within the pore.
    Journal of neurochemistry, 1999, Volume: 72, Issue:1

    Topics: Amino Acid Sequence; Animals; Antinematodal Agents; Binding Sites; Caenorhabditis elegans; Chloride Channels; Drug Interactions; Drug Resistance; Electrophysiology; GABA Antagonists; Glutamic Acid; Ion Channel Gating; Ivermectin; Kinetics; Membrane Potentials; Molecular Sequence Data; Oocytes; Picrotoxin; Point Mutation; Protein Structure, Tertiary; Xenopus

1999
Haemonchus contortus: characterization of a glutamate binding site in unselected and ivermectin-selected larvae and adults.
    Experimental parasitology, 1999, Volume: 92, Issue:1

    Topics: Animals; Anthelmintics; Binding Sites; Chloride Channels; Drug Resistance; Glutamic Acid; Haemonchus; Ivermectin; Kinetics; Larva; Receptors, Glutamate

1999
Haemonchus contortus: effects of glutamate, ivermectin, and moxidectin on inulin uptake activity in unselected and ivermectin-selected adults.
    Experimental parasitology, 1999, Volume: 92, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Antinematodal Agents; Female; Glutamic Acid; Haemonchus; Inulin; Ivermectin; Macrolides; Male; Movement

1999
The genetics of ivermectin resistance in Caenorhabditis elegans.
    Proceedings of the National Academy of Sciences of the United States of America, 2000, Mar-14, Volume: 97, Issue:6

    Topics: Animals; Antinematodal Agents; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Chloride Channels; Cloning, Molecular; Drug Resistance; Electrophysiology; Glutamic Acid; Helminth Proteins; Ivermectin; Models, Biological; Models, Genetic; Mutation; Pharynx; Protein Binding

2000
Characterization of glutamate-gated chloride channels in the pharynx of wild-type and mutant Caenorhabditis elegans delineates the role of the subunit GluCl-alpha2 in the function of the native receptor.
    Molecular pharmacology, 2001, Volume: 59, Issue:5

    Topics: Animals; Antinematodal Agents; Caenorhabditis elegans; Chloride Channels; Dose-Response Relationship, Drug; Glutamic Acid; Ivermectin; Mutation; Osmolar Concentration; Pharynx; Receptors, Glutamate; Transfection; Xenopus laevis

2001
High-affinity ivermectin binding to recombinant subunits of the Haemonchus contortus glutamate-gated chloride channel.
    Molecular and biochemical parasitology, 2001, Volume: 114, Issue:2

    Topics: Animals; Caenorhabditis elegans; Chloride Channels; Cloning, Molecular; Female; Glutamic Acid; Haemonchus; Ivermectin; Kinetics; Molecular Sequence Data; Oocytes; Phylogeny; Protein Subunits; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Transfection

2001
A glutamate-gated chloride channel subunit from Haemonchus contortus: expression in a mammalian cell line, ligand binding, and modulation of anthelmintic binding by glutamate.
    Biochemical pharmacology, 2002, Mar-15, Volume: 63, Issue:6

    Topics: Animals; Anthelmintics; Anti-Bacterial Agents; Binding, Competitive; Cell Line; Chloride Channels; COS Cells; Drug Interactions; Glutamic Acid; Haemonchus; Helminth Proteins; Ivermectin; Kinetics; Ligands; Macrolides; Mammals; Transfection; Tritium

2002
Ivermectin and nodulisporic acid receptors in Drosophila melanogaster contain both gamma-aminobutyric acid-gated Rdl and glutamate-gated GluCl alpha chloride channel subunits.
    Biochemistry, 2002, May-21, Volume: 41, Issue:20

    Topics: Animals; Binding Sites; Cell Membrane; Chloride Channels; Drosophila melanogaster; Drosophila Proteins; gamma-Aminobutyric Acid; Glutamic Acid; Immune Sera; Indoles; Ion Channel Gating; Ivermectin; Precipitin Tests; Radioligand Assay; Receptors, Drug; Receptors, GABA-A; Solubility; Sulfur Radioisotopes

2002
Selective electrical silencing of mammalian neurons in vitro by the use of invertebrate ligand-gated chloride channels.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, Sep-01, Volume: 22, Issue:17

    Topics: Action Potentials; Animals; Caenorhabditis elegans; Cells, Cultured; Chloride Channels; Chlorides; Electric Stimulation; Feasibility Studies; gamma-Aminobutyric Acid; Genes, Reporter; Genetic Vectors; Glutamic Acid; Humans; Ion Channel Gating; Ivermectin; Kidney; Ligands; Luminescent Proteins; Neural Inhibition; Neurons; Patch-Clamp Techniques; Rats; Sindbis Virus; Synaptic Transmission; Transfection

2002
Selective elimination of glutamate activation and introduction of fluorescent proteins into a Caenorhabditis elegans chloride channel.
    FEBS letters, 2002, Sep-25, Volume: 528, Issue:1-3

    Topics: Amino Acid Sequence; Animals; Bacterial Proteins; Base Sequence; Binding Sites; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Chloride Channels; DNA, Complementary; Female; Glutamic Acid; Green Fluorescent Proteins; In Vitro Techniques; Ivermectin; Kinetics; Ligands; Luminescent Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Oocytes; Protein Structure, Tertiary; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Xenopus laevis

2002
Mutations in the extracellular domains of glutamate-gated chloride channel alpha3 and beta subunits from ivermectin-resistant Cooperia oncophora affect agonist sensitivity.
    Journal of neurochemistry, 2004, Volume: 89, Issue:5

    Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Antinematodal Agents; Cells, Cultured; Chloride Channel Agonists; Chloride Channels; Dose-Response Relationship, Drug; Drug Resistance; Glutamic Acid; Ivermectin; Ligands; Macrolides; Molecular Sequence Data; Mutation; Oocytes; Patch-Clamp Techniques; Protein Structure, Tertiary; Protein Subunits; Sequence Homology, Amino Acid; Trichostrongyloidea; Xenopus laevis

2004
Genetic variability of glutamate-gated chloride channel genes in ivermectin-susceptible and -resistant strains of Cooperia oncophora.
    Parasitology, 2004, Volume: 129, Issue:Pt 6

    Topics: Amino Acid Sequence; Animals; Antinematodal Agents; Chloride Channels; Drug Resistance; Genetic Variation; Glutamic Acid; Helminth Proteins; Ion Channel Gating; Ivermectin; Molecular Sequence Data; Phylogeny; Sequence Alignment; Sequence Homology, Amino Acid; Trichostrongyloidea

2004
Actions of glutamate and ivermectin on the pharyngeal muscle of Ascaridia galli: a comparative study with Caenorhabditis elegans.
    International journal for parasitology, 2006, Volume: 36, Issue:4

    Topics: Action Potentials; Animals; Antinematodal Agents; Ascaridia; Caenorhabditis elegans; Chloride Channels; Chlorides; Dose-Response Relationship, Drug; Electrophysiology; Glutamic Acid; Ivermectin; Membrane Potentials; Pharyngeal Muscles; Picrotoxin; Species Specificity

2006
Dorsal unpaired median neurons of locusta migratoria express ivermectin- and fipronil-sensitive glutamate-gated chloride channels.
    Journal of neurophysiology, 2007, Volume: 97, Issue:4

    Topics: Algorithms; Amino Acid Sequence; Animals; Chloride Channels; Cloning, Molecular; Data Interpretation, Statistical; DNA, Complementary; Ganglia, Invertebrate; Glutamic Acid; Insecticides; Ion Channel Gating; Ivermectin; Kinetics; Locusta migratoria; Molecular Sequence Data; Neurons; Patch-Clamp Techniques; Pyrazoles; Reverse Transcriptase Polymerase Chain Reaction

2007
Inhibitory neurotransmission and olfactory memory in honeybees.
    Neurobiology of learning and memory, 2008, Volume: 90, Issue:4

    Topics: Animals; Bees; Chloride Channels; Dicarboxylic Acids; gamma-Aminobutyric Acid; Glutamic Acid; Ivermectin; Mandible; Memory; Pyrrolidines; Smell; Synaptic Transmission

2008
An ivermectin-sensitive glutamate-gated chloride channel from the parasitic nematode Haemonchus contortus.
    Molecular pharmacology, 2009, Volume: 75, Issue:6

    Topics: Animals; Anthelmintics; Chloride Channel Agonists; Chloride Channels; Chlorocebus aethiops; COS Cells; Drug Resistance; Female; Glutamic Acid; Haemonchus; Ion Channel Gating; Ivermectin; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Oocytes; Patch-Clamp Techniques; Protein Conformation; Protein Subunits; Radioligand Assay; Xenopus laevis

2009
The actions of chloride channel blockers, barbiturates and a benzodiazepine on Caenorhabditis elegans glutamate- and ivermectin-gated chloride channel subunits expressed in Xenopus oocytes.
    Invertebrate neuroscience : IN, 2009, Volume: 9, Issue:3-4

    Topics: Animals; Anthelmintics; Barbiturates; Benzodiazepines; Caenorhabditis elegans; Chloride Channels; Female; Glutamic Acid; Ivermectin; Nitrobenzoates; Oocytes; Patch-Clamp Techniques; Picrotoxin; Stilbenes; Xenopus

2009
An engineered glutamate-gated chloride (GluCl) channel for sensitive, consistent neuronal silencing by ivermectin.
    The Journal of biological chemistry, 2013, Jul-19, Volume: 288, Issue:29

    Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Cell Membrane; Chloride Channels; Endoplasmic Reticulum; Glutamic Acid; HEK293 Cells; Humans; Ion Channel Gating; Ivermectin; Luminescent Proteins; Molecular Sequence Data; Mutant Proteins; Mutation; Neurons; Protein Engineering; Protein Multimerization; Protein Subunits; Rats; Rats, Wistar

2013
X-ray structures of GluCl in apo states reveal a gating mechanism of Cys-loop receptors.
    Nature, 2014, Aug-21, Volume: 512, Issue:7514

    Topics: Allosteric Regulation; Animals; Apoproteins; Binding Sites; Binding, Competitive; Caenorhabditis elegans; Cell Membrane; Chloride Channels; Crystallography, X-Ray; Cysteine Loop Ligand-Gated Ion Channel Receptors; Drug Partial Agonism; Glutamic Acid; Ion Channel Gating; Ivermectin; Ligands; Models, Molecular; Movement; Phosphatidylcholines; Protein Binding; Protein Multimerization; Protein Structure, Tertiary; Structure-Activity Relationship

2014
Identification and functional expression of a glutamate- and avermectin-gated chloride channel from Caligus rogercresseyi, a southern Hemisphere sea louse affecting farmed fish.
    PLoS pathogens, 2014, Volume: 10, Issue:9

    Topics: Amino Acid Sequence; Animals; Caenorhabditis elegans; Chloride Channels; Cloning, Molecular; Copepoda; Electrophysiology; Female; Fish Diseases; Fishes; Glutamic Acid; Insecticides; Ivermectin; Models, Molecular; Molecular Docking Simulation; Molecular Sequence Data; Oocytes; Sequence Homology, Amino Acid; Xenopus laevis

2014
Exon 3 splicing and mutagenesis identify residues influencing cell surface density of heterologously expressed silkworm (Bombyx mori) glutamate-gated chloride channels.
    Molecular pharmacology, 2014, Volume: 86, Issue:6

    Topics: Amino Acid Sequence; Animals; Bombyx; Chloride Channels; Exons; Glutamic Acid; HEK293 Cells; Humans; Ivermectin; Models, Molecular; Molecular Sequence Data; Mutagenesis; RNA Splicing; Structure-Activity Relationship; Xenopus laevis

2014
Conformational gating dynamics in the GluCl anion-selective chloride channel.
    ACS chemical neuroscience, 2015, Aug-19, Volume: 6, Issue:8

    Topics: Chloride Channels; Glutamic Acid; Hydrogen Bonding; Ivermectin; Molecular Dynamics Simulation; Protein Conformation

2015
Characterization of the target of ivermectin, the glutamate-gated chloride channel, from Anopheles gambiae.
    The Journal of experimental biology, 2015, May-15, Volume: 218, Issue:Pt 10

    Topics: Age Factors; Alternative Splicing; Animals; Anopheles; Chloride Channels; Female; Glutamic Acid; Insect Vectors; Insecticides; Ivermectin; Male; Oocytes; Xenopus laevis

2015
Electrophysiological characterization of ivermectin triple actions on Musca chloride channels gated by l-glutamic acid and γ-aminobutyric acid.
    Insect biochemistry and molecular biology, 2016, Volume: 77

    Topics: Animals; Chloride Channels; Electrophysiological Phenomena; Female; gamma-Aminobutyric Acid; Glutamic Acid; Houseflies; Insecticides; Ivermectin

2016
From the Cover: Functional Analysis Reveals Glutamate and Gamma-Aminobutyric Acid-Gated Chloride Channels as Targets of Avermectins in the Carmine Spider Mite.
    Toxicological sciences : an official journal of the Society of Toxicology, 2017, Volume: 155, Issue:1

    Topics: Amino Acid Sequence; Animals; Chloride Channels; gamma-Aminobutyric Acid; Glutamic Acid; Ivermectin; Mites; Sequence Homology, Amino Acid

2017
Mutations on M3 helix of Plutella xylostella glutamate-gated chloride channel confer unequal resistance to abamectin by two different mechanisms.
    Insect biochemistry and molecular biology, 2017, Volume: 86

    Topics: Amino Acid Sequence; Animals; Chloride Channels; Glutamic Acid; Insect Proteins; Insecticide Resistance; Insecticides; Ivermectin; Molecular Sequence Data; Moths; Mutation; Xenopus laevis

2017
An L319F mutation in transmembrane region 3 (TM3) selectively reduces sensitivity to okaramine B of the Bombyx mori l-glutamate-gated chloride channel.
    Bioscience, biotechnology, and biochemistry, 2017, Volume: 81, Issue:10

    Topics: Amino Acid Sequence; Animals; Azetidines; Azocines; Bombyx; Cell Membrane; Chloride Channels; Dose-Response Relationship, Drug; Drug Interactions; Glutamic Acid; Indole Alkaloids; Insect Proteins; Ivermectin; Models, Molecular; Mutation; Protein Conformation; Sequence Alignment

2017
Effects of glutamate and ivermectin on single glutamate-gated chloride channels of the parasitic nematode H. contortus.
    PLoS pathogens, 2017, Volume: 13, Issue:10

    Topics: Animals; Anthelmintics; Caenorhabditis elegans; Chloride Channels; Glutamic Acid; Haemonchus; HEK293 Cells; Humans; Ivermectin; Mutation

2017
Un-gating and allosteric modulation of a pentameric ligand-gated ion channel captured by molecular dynamics.
    PLoS computational biology, 2017, Volume: 13, Issue:10

    Topics: Allosteric Regulation; Allosteric Site; Binding Sites; Chloride Channels; Glutamic Acid; Ion Channel Gating; Ivermectin; Ligand-Gated Ion Channels; Ligands; Models, Chemical; Molecular Dynamics Simulation; Neurotransmitter Agents; Protein Binding; Protein Conformation

2017
The fungal alkaloid Okaramine-B activates an L-glutamate-gated chloride channel from Ixodes scapularis, a tick vector of Lyme disease.
    International journal for parasitology. Drugs and drug resistance, 2018, Volume: 8, Issue:2

    Topics: Abelmoschus; Acaricides; Animals; Azetidines; Azocines; Chloride Channels; Disease Vectors; Drug Discovery; Glutamic Acid; Indole Alkaloids; Ivermectin; Ixodes; Lyme Disease; Oocytes; Penicillium; Xenopus laevis

2018
GluClR-mediated inhibitory postsynaptic currents reveal targets for ivermectin and potential mechanisms of ivermectin resistance.
    PLoS pathogens, 2019, Volume: 15, Issue:1

    Topics: Animals; Chloride Channels; Excitatory Amino Acid Antagonists; Glutamic Acid; Haemonchus; HEK293 Cells; Humans; Inhibitory Postsynaptic Potentials; Ivermectin; Patch-Clamp Techniques; Receptors, Glutamate; Xenopus laevis

2019
The effects of insecticides on two splice variants of the glutamate-gated chloride channel receptor of the major malaria vector, Anopheles gambiae.
    British journal of pharmacology, 2020, Volume: 177, Issue:1

    Topics: Amino Acid Sequence; Animals; Anopheles; Chloride Channels; Dose-Response Relationship, Drug; Female; Glutamic Acid; Insecticides; Ivermectin; Mosquito Vectors; Oocytes; Protein Isoforms; Xenopus laevis

2020
Nodulisporic acid produces direct activation and positive allosteric modulation of AVR-14B, a glutamate-gated chloride channel from adult
    Proceedings of the National Academy of Sciences of the United States of America, 2022, 08-23, Volume: 119, Issue:34

    Topics: Animals; Brugia malayi; Chloride Channels; Glutamic Acid; Indoles; Ivermectin; Ligands

2022
A new family of glutamate-gated chloride channels in parasitic sea louse Caligus rogercresseyi: A subunit refractory to activation by ivermectin is dominant in heteromeric assemblies.
    PLoS pathogens, 2023, Volume: 19, Issue:3

    Topics: Animals; Chloride Channels; Copepoda; Glutamic Acid; Ivermectin; Parasites; Phthiraptera

2023