glutamic acid has been researched along with d-alpha tocopherol in 61 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (4.92) | 18.7374 |
| 1990's | 19 (31.15) | 18.2507 |
| 2000's | 26 (42.62) | 29.6817 |
| 2010's | 13 (21.31) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Sinitsyn, SP | 1 |
| Orten, DK; Owen, MD; Perchellet, JP; Posey, TD; Schneider, BA | 1 |
| Bova, IIa; Karlov, VA; Makarov, VA | 1 |
| Behl, C; Holsboer, F; Trapp, T; Widmann, M | 1 |
| Goodman, Y; Mattson, MP | 1 |
| Pokras, RS | 1 |
| Govitrapong, P; Kittiwatanapaisan, W; Kotchabhakdi, N; Wilairat, P | 1 |
| al-Sawaf, HA; al-Shabanah, OA; Hassan, MT; Khairaldin, AA; Mostafa, YH | 1 |
| Bolevich, S; Daniliak, IG; Kogan, AKh | 1 |
| Oliveira, CR; Pereira, CM | 1 |
| Brown, DR; Kretzschmar, HA; Schmidt, B; Schulz-Schaeffer, WJ | 1 |
| Ciani, E; Contestabile, A; Dall'Olio, R; Gandolfi, O; Sparapani, M | 1 |
| Lai, JC; Quach, HT; Smith, WE; Vatassery, GT | 1 |
| Oliveira, C; Pereira, C; Santos, MS | 1 |
| Andreeva, NA; Avrova, NF; Gonchar, VS; Sokolova, TV; Stelmaschuk, EV; Tyurin, VA; Tyurina, YY; Victorov, IV; Zakharova, IO | 1 |
| Heinemann, U; Müller, W; Schuchmann, S | 1 |
| Funato, H; Kohsaka, S; Mochizuki, H; Shimojo, M; Takasugi, K; Yamamoto, I | 1 |
| Cunha, GM; França, MC; Moraes, GA; Moraes, MO; Moraes, RA; Viana, GS | 1 |
| Avrova, NF; Shestak, KI; Sokolova, TV; Tiurin, VA; Tiurina, IuIu; Zakharova, IO | 1 |
| Adams, MR; Celermajer, DS; Phu, CV; Stocker, R | 1 |
| Carlo, D; Chang, J; Gillenwater, G; Hendler, S; Khoh-Reiter, S; Sagara, Y; Schubert, D | 1 |
| Kruman, II; Mattson, MP; Pedersen, WA; Springer, JE | 1 |
| Han, D; Kobayashi, MS; Packer, L | 1 |
| Khanna, S; Packer, L; Roy, S; Sen, CK | 1 |
| Packer, L; Roy, S; Sen, CK; Tirosh, O | 1 |
| Lynch, MA; O'Donnell, E; Vereker, E | 1 |
| Ishige, K; Sagara, Y; Schubert, D | 1 |
| Behl, C | 1 |
| García, O; Massieu, L | 1 |
| Karg, E; Klivényi, P; Pinter, S; Tajti, J; Vécsei, L | 1 |
| Brera, B; de Ceballos, ML; Fernández-Tomé, MP | 1 |
| Daskalopoulos, R; Farhangkhgoee, P; Gelb, AW; Karmazyn, M; Korcok, J; Wilson, JX | 1 |
| Hori, M; Kitagawa, K; Kuwabara, K; Matsumoto, M; Matsushita, K; Ohtsuki, T; Sasaki, T; Takasawa, K; Tanaka, S; Yanagihara, T | 1 |
| Bahadduri, P; Khanna, S; Ratan, RR; Roy, S; Ryu, H; Sen, CK; Swaan, PW | 1 |
| Balasubramanian, KA; Prabhu, R; Thomas, S | 1 |
| Khanna, S; Roy, S; Sen, CK | 1 |
| Adamo, EB; Caccamo, D; Campisi, A; Ientile, R; Li Volti, G; Marini, H; Squadrito, F | 1 |
| Ezaki, Y; Kitagawa, N; Matsuo, T; Nagata, I; Nishihara, E; Shibata, Y; Shinohara, K | 1 |
| Jiang, A; Kraus, RL; Lariosa-Willingham, K; Pasieczny, R; Trauger, JW; Turner, MS | 1 |
| Chaki, S; Craft, TK; DeVries, AC; Khanna, S; Notestine, MA; Parinandi, NL; Rink, C; Roy, S; Sen, CK; Slivka, A | 1 |
| Akaike, A; Hakozaki, H; Komasaka, K; Kotake, Y; Kume, T; Nakatsu, Y; Ohta, S; Taguchi, R | 1 |
| Lee, SM; Lee, WY | 1 |
| Chan, MH; Chen, HH; Ko, CH; Lin, YR | 1 |
| Bach, A; Bähr, M; Bartels, C; Bohn, M; Dietrich, J; Ehrenreich, H; Hardeland, R; Hüther, G; Mertens, N; Nave, KA; Poeggeler, B; Pölking, E; Rohde, G; Schneider, A; Sirén, AL; Sperling, S; Weishaupt, JH | 1 |
| Massieu, L; Mejía-Toiber, J; Montiel, T | 1 |
| Barger, SW; Beggs, ML; Goodwin, ME; Porter, MM | 1 |
| Elsasser, TH; Garrett, WM; Kahl, S; Li, CJ; Rodrigo, J; Sartin, JL | 1 |
| Wang, SJ; Yang, TT | 1 |
| Bibus, D; Khanna, S; Kotha, SR; Parinandi, NL; Rink, C; Roy, S; Sen, CK | 1 |
| Barbanel, G; Cohen-Solal, C; Crouzin, N; Ferreira, MC; Guiramand, J; Vignes, M | 1 |
| Jeong, BS; Nam, TG; Niki, E; Omata, Y; Porter, NA; Saito, Y; Serwa, R; Yoshida, Y | 1 |
| Akazawa, YO; Miyama, A; Niki, E; Nishio, K; Noguchi, N; Saito, Y; Yamanaka, K; Yoshida, Y | 1 |
| Aguilera, P; Chánez-Cárdenas, ME; Espinoza-Rojo, M; Iturralde-Rodríguez, KI; Ruiz-Tachiquín, ME | 1 |
| Gao, J; Lu, J; Ouyang, L; Shen, Y; Shi, X; Tian, Y; Yang, J | 1 |
| Abd Mutalib, MS; Khaza'ai, H; Selvaraju, TR; Vasudevan, R; Vidyadaran, S | 1 |
| Hamdan, Y; Khaza'ai, H; Ramachandran, V; Rati Selvaraju, T; Sokhini Abd Mutalib, M; Vidyadaran, S | 1 |
| Di, X; Fu, Q; He, Z; Kan, Q; Li, L; Liu, H; Lu, T; Sun, J; Wang, Y; Zhang, S | 1 |
| Deng, C; Meng, F; Wu, J; Zhang, J; Zhong, Z | 1 |
| Fan, ZL; Jin, BH; Lin, MT; Shen, BX; Sohawon, Y; Tong, MQ; Xu, HL; Yao, Q; Zhao, YZ; Zhu, QY; ZhuGe, DL | 1 |
| Gould, RL; Pazdro, R | 1 |
3 review(s) available for glutamic acid and d-alpha tocopherol
| Article | Year |
|---|---|
Tocotrienol: the natural vitamin E to defend the nervous system?
Topics: Animals; Arachidonate 12-Lipoxygenase; Brain; Cell Death; CSK Tyrosine-Protein Kinase; Diet; Dietary Supplements; Gene Expression; Glutamic Acid; Humans; Nervous System Physiological Phenomena; Neurons; Protein-Tyrosine Kinases; src-Family Kinases; Tocotrienols; Vitamin E | 2004 |
Glucose transporters regulation on ischemic brain: possible role as therapeutic target.
Topics: Animals; Brain Chemistry; Brain Ischemia; Estrogens; Excitatory Amino Acid Agonists; Garlic; Glucose; Glucose Transport Proteins, Facilitative; Glutamic Acid; Humans; Ischemic Preconditioning; Mitochondria; Plant Extracts; Up-Regulation; Vitamin E | 2010 |
Impact of Supplementary Amino Acids, Micronutrients, and Overall Diet on Glutathione Homeostasis.
Topics: Amino Acids; Animals; Antioxidants; Ascorbic Acid; Cysteine; Diet; Dietary Supplements; Glutamic Acid; Glutathione; Glycine; Homeostasis; Humans; Micronutrients; Oxidative Stress; Vitamin E | 2019 |
2 trial(s) available for glutamic acid and d-alpha tocopherol
| Article | Year |
|---|---|
[Aevit and glutamic acid in the treatment of patients with bronchial asthma].
Topics: Adolescent; Adult; Aged; Antioxidants; Asthma; Drug Combinations; Female; Free Radicals; Glucocorticoids; Glutamic Acid; Humans; Luminescent Measurements; Male; Malondialdehyde; Middle Aged; Vitamin A; Vitamin E | 1995 |
Reduced oxidative damage in ALS by high-dose enteral melatonin treatment.
Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Animals; Biomarkers; Cell Line; Cytoprotection; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Glutamic Acid; Humans; Male; Melatonin; Mice; Mice, Transgenic; Middle Aged; Neurons; Oxidative Stress; Reactive Oxygen Species; Superoxide Dismutase; Superoxide Dismutase-1; Survival Rate; Vitamin E | 2006 |
56 other study(ies) available for glutamic acid and d-alpha tocopherol
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
[Correction of metabolic disorders of the myocardium in acute myocardial infarct as an important factor in preventing the development of circulatory insufficiency].
Topics: Animals; Aprotinin; Ascorbic Acid; Drug Therapy, Combination; Glutamates; Glutamic Acid; Heart Failure; Ibuprofen; Myocardial Infarction; Myocardium; Nandrolone; Nandrolone Decanoate; Nifedipine; Potassium Magnesium Aspartate; Propranolol; Rabbits; Sodium Oxybate; Vitamin E | 1985 |
Inhibitory effects of glutathione level-raising agents and D-alpha-tocopherol on ornithine decarboxylase induction and mouse skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate.
Topics: Amino Acids; Animals; Cysteine; Enzyme Induction; Female; gamma-Glutamyltransferase; Glutamate-Cysteine Ligase; Glutamates; Glutamic Acid; Glutathione; Glycine; In Vitro Techniques; Mice; Ornithine Decarboxylase; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Vitamin E | 1985 |
[Treatment of the syndrome of disseminated intravascular coagulation in ischemic strokes].
Topics: Adult; Aged; alpha-Tocopherol; Blood Transfusion; Brain Ischemia; Combined Modality Therapy; Dipyridamole; Disseminated Intravascular Coagulation; Fatty Acids, Unsaturated; Female; Glutamates; Glutamic Acid; Heparin; Humans; Male; Middle Aged; Phytic Acid; Plasma; Tocopherols; Vitamin E | 1984 |
17-beta estradiol protects neurons from oxidative stress-induced cell death in vitro.
Topics: Aldosterone; Alzheimer Disease; Amyloid beta-Peptides; Analysis of Variance; Animals; Antioxidants; beta-Galactosidase; Cell Death; Cell Line; Cell Survival; Cholesterol; Corticosterone; Estradiol; Glutamic Acid; Hippocampus; Humans; Hydrogen Peroxide; Luciferases; Mice; Neurons; Neurotoxins; Oxidative Stress; Progesterone; Receptors, Estrogen; Recombinant Fusion Proteins; Transfection; Vitamin E | 1995 |
Different amyloidogenic peptides share a similar mechanism of neurotoxicity involving reactive oxygen species and calcium.
Topics: Amyloid; Amyloid beta-Peptides; Animals; beta 2-Microglobulin; Calcium; Cell Death; Cells, Cultured; Glutamic Acid; Hippocampus; Islet Amyloid Polypeptide; Neurons; Rats; Reactive Oxygen Species; Vitamin E | 1995 |
A possible role of glutamate in the aging process.
Topics: Aging; Animals; Brain; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Headache; Humans; Rats; Vitamin E | 1994 |
Effect of dietary vitamin E on L-[3H]glutamate binding in rabbit cerebellum.
Topics: Animals; Cell Membrane; Cerebellum; Diet; Glutamates; Glutamic Acid; Rabbits; Receptors, Glutamate; Vitamin E | 1993 |
Vitamin E protects against bacterial endotoxin-induced increase of plasma corticosterone and brain glutamate in the rat.
Topics: Amino Acids; Animals; Brain; Corticosterone; Endotoxins; Glutamic Acid; Male; Rats; Rats, Wistar; Vitamin E | 1996 |
Glutamate toxicity on a PC12 cell line involves glutathione (GSH) depletion and oxidative stress.
Topics: Animals; Antioxidants; Benzoquinones; Cell Death; Cystine; Dithiothreitol; Glutamic Acid; Glutathione; Glutathione Reductase; Kinetics; L-Lactate Dehydrogenase; Oxidative Stress; PC12 Cells; Rats; Selegiline; Ubiquinone; Vitamin E | 1997 |
Prion protein-deficient cells show altered response to oxidative stress due to decreased SOD-1 activity.
Topics: Amino Acid Sequence; Amitrole; Animals; Cattle; Cell Survival; Cells, Cultured; Cerebellum; Cerebral Cortex; Ditiocarb; Embryo, Mammalian; Glutamic Acid; Ionomycin; Isoenzymes; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Knockout; Molecular Sequence Data; Neurons; NG-Nitroarginine Methyl Ester; Oxidative Stress; Peptide Fragments; Potassium Cyanide; Prions; PrPC Proteins; Superoxide Dismutase; Vitamin E | 1997 |
Neurotoxicity of polyamines and pharmacological neuroprotection in cultures of rat cerebellar granule cells.
Topics: 2-Amino-5-phosphonovalerate; Animals; Apoptosis; Aspartic Acid; Butylated Hydroxytoluene; Cells, Cultured; Cerebellar Cortex; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Female; Free Radical Scavengers; Glutamic Acid; L-Lactate Dehydrogenase; Male; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Nitric Oxide Synthase; Nitroarginine; Piperidines; Putrescine; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spermidine; Spermine; Vitamin E | 1997 |
Aging is associated with a decrease in synaptosomal glutamate uptake and an increase in the susceptibility of synaptosomal vitamin E to oxidative stress.
Topics: Aging; Animals; Brain; Female; Glutamic Acid; Oxidative Stress; Rats; Rats, Inbred F344; Subcellular Fractions; Synaptosomes; Vitamin E | 1998 |
Metabolic inhibition increases glutamate susceptibility on a PC12 cell line.
Topics: Adenosine Triphosphate; Animals; Antioxidants; Benzoquinones; Cell Hypoxia; Disease Susceptibility; Energy Metabolism; Glutamic Acid; Hypoglycemia; Ischemia; Mitochondria; PC12 Cells; Rats; Receptors, N-Methyl-D-Aspartate; Tetrazolium Salts; Thiazoles; Ubiquinone; Vitamin E | 1998 |
Inhibition of glutamate-induced intensification of free radical reactions by gangliosides: possible role in their protective effect in rat cerebellar granule cells and brain synaptosomes.
Topics: Animals; Ascorbic Acid; Cerebellum; Cytoplasmic Granules; G(M1) Ganglioside; Glutamic Acid; Lipid Peroxidation; Nitric Oxide; Rats; Rats, Wistar; Reactive Oxygen Species; Sodium-Potassium-Exchanging ATPase; Sulfhydryl Compounds; Superoxide Dismutase; Synaptosomes; Vitamin E | 1998 |
Altered Ca2+ signaling and mitochondrial deficiencies in hippocampal neurons of trisomy 16 mice: a model of Down's syndrome.
Topics: Aging; Alzheimer Disease; Animals; Calcium; Carcinogens; Cell Death; Cyclosporine; Diploidy; Disease Models, Animal; Down Syndrome; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Hippocampus; Karyotyping; Male; Membrane Potentials; Mice; Mice, Neurologic Mutants; Mitochondria; NADP; Neurons; Potassium; Quinoxalines; Signal Transduction; Trisomy; Vitamin E | 1998 |
Neuroprotective action of a novel compound--M50463--in primary cultured neurons.
Topics: Acetylcysteine; Animals; Antihypertensive Agents; Batrachotoxins; Binding Sites; Binding, Competitive; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cell Death; Cells, Cultured; Culture Media, Serum-Free; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Fetus; Glutamic Acid; Indoles; Neurons; Neuroprotective Agents; Neurotoxins; Nicardipine; Nitroprusside; Piperidines; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Sodium Channels; Thiazoles; Veratrine; Vitamin E | 1999 |
Nerve growth factor, ganglioside and vitamin E reverse glutamate cytotoxicity in hippocampal cells.
Topics: Animals; Animals, Newborn; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Drug Synergism; Gangliosides; Glutamic Acid; Hippocampus; Male; Nerve Growth Factors; Rats; Rats, Wistar; Vitamin E | 1999 |
[The antioxidant prevention of disorders in calcium ion metabolism under the action of glutamate on the synaptosomes of the rat cerebral cortex].
Topics: Animals; Antioxidants; Calcium; Calcium Metabolism Disorders; Cerebral Cortex; Gangliosides; Glutamic Acid; In Vitro Techniques; Male; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Superoxide Dismutase; Synaptosomes; Vitamin E | 1999 |
Lack of antioxidant activity of the antiatherogenic compound L-arginine.
Topics: Adult; Antioxidants; Arginine; Arteriosclerosis; Ascorbic Acid; Chromatography, High Pressure Liquid; Free Radical Scavengers; Glutamic Acid; Humans; Lipid Peroxides; Lipoproteins, LDL; Male; Nitric Oxide; Oxidation-Reduction; Reference Values; Vitamin E | 1999 |
Propofol hemisuccinate protects neuronal cells from oxidative injury.
Topics: Animals; Apoptosis; Buthionine Sulfoximine; Glutamic Acid; Hippocampus; Homocysteine; Hydrogen Peroxide; Methylprednisolone; Mice; Neurons; Neuroprotective Agents; Neurotoxins; Oxidative Stress; Propofol; Rats; Reactive Oxygen Species; Tocopherols; Vitamin E | 1999 |
ALS-linked Cu/Zn-SOD mutation increases vulnerability of motor neurons to excitotoxicity by a mechanism involving increased oxidative stress and perturbed calcium homeostasis.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antioxidants; Calcium; Cells, Cultured; Cyclic N-Oxides; Estradiol; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Free Radicals; Glutamic Acid; Homeostasis; Humans; Imidazoles; Lipid Peroxidation; Mice; Mice, Transgenic; Mitochondria; Motor Neuron Disease; Motor Neurons; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitrates; Oxidative Stress; Rhodamine 123; Spinal Cord; Superoxide Dismutase; Superoxides; Vitamin E | 1999 |
Antioxidants and herbal extracts protect HT-4 neuronal cells against glutamate-induced cytotoxicity.
Topics: Animals; Antioxidants; Cell Death; Cell Line; Excitatory Amino Acid Antagonists; Flavonoids; Free Radical Scavengers; Ginkgo biloba; Glutamic Acid; Glutathione; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Plant Extracts; Plants, Medicinal; Rats; Sulfhydryl Compounds; Vitamin E | 2000 |
Molecular basis of vitamin E action. Tocotrienol potently inhibits glutamate-induced pp60(c-Src) kinase activation and death of HT4 neuronal cells.
Topics: Animals; Benzoquinones; Cell Death; Cells, Cultured; Chelating Agents; Chromans; Chromatography, High Pressure Liquid; Deferoxamine; Enzyme Activation; Enzyme Inhibitors; Flow Cytometry; Glutamic Acid; Hippocampus; Immunoblotting; Lactams, Macrocyclic; Mice; Neurons; Phosphotyrosine; Proto-Oncogene Proteins pp60(c-src); Quinones; Rats; Signal Transduction; Time Factors; Tocotrienols; Transfection; Vitamin E | 2000 |
Cellular and mitochondrial changes in glutamate-induced HT4 neuronal cell death.
Topics: Animals; Calcium; Cell Death; Cell Survival; Cells, Cultured; DNA Fragmentation; Glutamic Acid; Glutathione; Intracellular Fluid; Membrane Potentials; Mice; Mitochondria; Neurons; Neurotoxins; Reactive Oxygen Species; Vitamin E | 2000 |
The inhibitory effect of interleukin-1beta on long-term potentiation is coupled with increased activity of stress-activated protein kinases.
Topics: Analysis of Variance; Animals; Ascorbic Acid; Dietary Supplements; Electric Stimulation; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Injections, Intraventricular; Interleukin-1; JNK Mitogen-Activated Protein Kinases; Long-Term Potentiation; Male; Mitogen-Activated Protein Kinases; Neural Inhibition; p38 Mitogen-Activated Protein Kinases; Potassium Chloride; Protein Kinases; Rats; Rats, Wistar; Reactive Oxygen Species; Synapses; Synaptosomes; Vitamin E | 2000 |
Flavonoids protect neuronal cells from oxidative stress by three distinct mechanisms.
Topics: Animals; Antioxidants; Calcium; Cell Death; Cell Line; Flavonoids; Free Radicals; Glutamic Acid; Glutathione; Hippocampus; Mice; Neurons; Oxidative Stress; Reactive Oxygen Species; Vitamin E | 2001 |
Vitamin E protects neurons against oxidative cell death in vitro more effectively than 17-beta estradiol and induces the activity of the transcription factor NF-kappaB.
Topics: Animals; Cell Death; Cell Survival; Cells, Cultured; Cerebellum; Estradiol; Glutamic Acid; Hippocampus; Humans; Hydrogen Peroxide; Mice; Neurons; NF-kappa B; Oxidants; Oxidative Stress; Rats; Rats, Sprague-Dawley; Vitamin E | 2000 |
Strategies for neuroprotection against L-trans-2,4-pyrrolidine dicarboxylate-induced neuronal damage during energy impairment in vitro.
Topics: Animals; Cell Survival; Cells, Cultured; Cerebellum; Coloring Agents; Convulsants; Cyclic N-Oxides; Dicarboxylic Acids; Energy Metabolism; Enzyme Inhibitors; Glutamic Acid; Mitochondria; Neurons; Neuroprotective Agents; Neurotransmitter Uptake Inhibitors; Nitro Compounds; Nitrogen Oxides; Propionates; Pyrrolidines; Rats; Rats, Wistar; Sodium Azide; Tetrazolium Salts; Thiazoles; Vitamin E | 2001 |
Sodium azide treatment decreases striatal and cortical concentrations of alpha-tocopherol in rats.
Topics: Animals; Cerebral Cortex; Electron Transport; Energy Metabolism; Enzyme Inhibitors; Free Radicals; Glutamic Acid; Glutathione; Lipid Peroxidation; Male; Neostriatum; Neurodegenerative Diseases; Nitric Oxide; Oxidative Stress; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sodium Azide; Subcellular Fractions; Vitamin E | 2001 |
beta-Amyloid-induced cytotoxicity, peroxide generation and blockade of glutamate uptake in cultured astrocytes.
Topics: Acetylcysteine; Amyloid beta-Peptides; Astrocytes; Catalase; Cell Survival; Cells, Cultured; Dithiothreitol; Dose-Response Relationship, Drug; Free Radicals; Glutamic Acid; Humans; Neurons; Peptide Fragments; Peroxides; Time Factors; Vitamin E | 2001 |
Propofol protection of sodium-hydrogen exchange activity sustains glutamate uptake during oxidative stress.
Topics: Amiloride; Anesthetics, Intravenous; Animals; Astrocytes; Bicarbonates; Cells, Cultured; Free Radical Scavengers; Glutamic Acid; Glutathione; Hydrogen-Ion Concentration; Microscopy, Fluorescence; Neuroprotective Agents; Oxidative Stress; Propofol; Rats; Rats, Wistar; Sodium-Hydrogen Exchangers; tert-Butylhydroperoxide; Tritium; Vitamin E | 2001 |
Protective effect of apolipoprotein E against ischemic neuronal injury is mediated through antioxidant action.
Topics: Animals; Antioxidants; Apolipoproteins E; Cell Survival; Cells, Cultured; Cytoprotection; Glutamic Acid; Hydrogen Peroxide; Ischemic Attack, Transient; Mice; Mice, Knockout; Neurons; Prosencephalon; Staurosporine; Vitamin E | 2002 |
Molecular basis of vitamin E action: tocotrienol modulates 12-lipoxygenase, a key mediator of glutamate-induced neurodegeneration.
Topics: Animals; Arachidonate 12-Lipoxygenase; Binding Sites; Cell Death; Cell Survival; Cells, Cultured; Cytosol; Glutamic Acid; Glutathione; Hippocampus; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence; Models, Molecular; Neurodegenerative Diseases; Neurons; Neurotoxins; Protein Structure, Secondary; Protein Structure, Tertiary; Rats; Rats, Sprague-Dawley; Time Factors; Tocotrienols; Vitamin E | 2003 |
Oral glutamine attenuates surgical manipulation-induced alterations in the intestinal brush border membrane.
Topics: Alanine; Alkaline Phosphatase; alpha-Tocopherol; Animals; Biological Transport; Female; Glucose; Glutamic Acid; Glutamine; Glutathione; Glycine; Intestines; Lipid Peroxidation; Male; Microvilli; Oxidative Stress; Phospholipids; Rats; Rats, Wistar | 2003 |
Glutamate promotes NF-kappaB pathway in primary astrocytes: protective effects of IRFI 016, a synthetic vitamin E analogue.
Topics: Analysis of Variance; Animals; Animals, Newborn; Astrocytes; Benzofurans; Cells, Cultured; Dose-Response Relationship, Drug; Electrophoretic Mobility Shift Assay; Epistasis, Genetic; Free Radical Scavengers; Glutamic Acid; Glutathione; L-Lactate Dehydrogenase; NF-kappa B; Rats; Rats, Wistar; Reactive Oxygen Species; Signal Transduction; Vitamin E | 2005 |
Vitamin E prevents the neuronal cell death by repressing cyclooxygenase-2 activity.
Topics: Animals; Antioxidants; Cell Death; Cell Line; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Gene Expression Regulation; Glutamic Acid; Hippocampus; Immunohistochemistry; Mice; Neurons; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfonamides; Time Factors; Vitamin E | 2005 |
Antioxidant properties of minocycline: neuroprotection in an oxidative stress assay and direct radical-scavenging activity.
Topics: Animals; Antioxidants; Antipyrine; Benzothiazoles; Cell Death; Cells, Cultured; Cerebral Cortex; Chromans; Deoxyribose; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Edaravone; Embryo, Mammalian; Free Radical Scavengers; Free Radicals; Glutamic Acid; Inhibitory Concentration 50; L-Lactate Dehydrogenase; Lipid Peroxidation; Minocycline; Neurons; Neuroprotective Agents; Oxidative Stress; Phenethylamines; Rats; Rats, Sprague-Dawley; Sulfonic Acids; Vitamin E | 2005 |
Neuroprotective properties of the natural vitamin E alpha-tocotrienol.
Topics: Animals; Antioxidants; Arachidonate 12-Lipoxygenase; Brain; Cell Death; Cell Line; Cell Survival; Cells, Cultured; Cerebral Cortex; CSK Tyrosine-Protein Kinase; Fluoresceins; Glutamic Acid; Hippocampus; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Neuroprotective Agents; Organic Chemicals; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins pp60(c-src); Random Allocation; Rats; Rats, Inbred SHR; src-Family Kinases; Stroke; Time Factors; Tocotrienols; Transfection; Tyrosine; Vitamin E | 2005 |
Glutamate excitotoxicity is involved in cell death caused by tributyltin in cultured rat cortical neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Tocopherol; Animals; Butadienes; Cell Death; Cell Survival; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Antagonism; Environmental Pollutants; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Female; Fetus; Glutamic Acid; Imidazoles; Nitriles; Pregnancy; Pyridines; Rats; Rats, Wistar; Receptors, Glutamate; Trialkyltin Compounds | 2006 |
Protective effects of alpha-tocopherol and ischemic preconditioning on hepatic reperfusion injury.
Topics: Alanine Transaminase; alpha-Tocopherol; Animals; Antioxidants; Disease Models, Animal; Glutamic Acid; Glutathione Disulfide; Ischemic Preconditioning; Liver; Liver Diseases; Male; Malondialdehyde; Mitochondria, Liver; Mitochondrial Swelling; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2005 |
Neuroprotective activity of honokiol and magnolol in cerebellar granule cell damage.
Topics: Animals; Antioxidants; Biphenyl Compounds; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glucose; Glutamic Acid; Hydrogen Peroxide; L-Lactate Dehydrogenase; Lignans; Mitochondria; N-Methylaspartate; Neurons; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Sprague-Dawley; Vitamin E | 2006 |
D-beta-hydroxybutyrate prevents glutamate-mediated lipoperoxidation and neuronal damage elicited during glycolysis inhibition in vivo.
Topics: 3-Hydroxybutyric Acid; Adenosine Triphosphate; Alkylating Agents; Animals; Antioxidants; Glutamic Acid; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycolysis; Iodoacetates; Lipid Peroxidation; Male; Malondialdehyde; Neostriatum; Neurons; Oxidative Stress; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances; Vitamin E | 2006 |
Glutamate release from activated microglia requires the oxidative burst and lipid peroxidation.
Topics: Acetophenones; Animals; Animals, Newborn; Antioxidants; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Glutamic Acid; Lipid Peroxidation; Lipopolysaccharides; Microglia; Models, Biological; Onium Compounds; Oxidation-Reduction; Rats; Vitamin E | 2007 |
Caveolae nitration of Janus kinase-2 at the 1007Y-1008Y site: coordinating inflammatory response and metabolic hormone readjustment within the somatotropic axis.
Topics: Amino Acid Sequence; Animals; Antibodies; Antioxidants; Aspartic Acid; Binding Sites; Cattle; Caveolae; Epitopes; Glutamic Acid; Inflammation; Insulin-Like Growth Factor I; Janus Kinase 2; Lipopolysaccharides; Molecular Sequence Data; Nitrates; Nitric Oxide Synthase Type III; Phosphorylation; Rabbits; RNA, Messenger; Stress, Physiological; Suppressor of Cytokine Signaling Proteins; Tyrosine; Vitamin E | 2007 |
Facilitatory effect of glutamate exocytosis from rat cerebrocortical nerve terminals by alpha-tocopherol, a major vitamin E component.
Topics: 4-Aminopyridine; alpha-Tocopherol; Animals; Calcium Channels; Calcium Signaling; Cerebral Cortex; Enzyme Activation; Exocytosis; Glutamic Acid; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Metalloendopeptidases; Myristoylated Alanine-Rich C Kinase Substrate; Potassium Channel Blockers; Presynaptic Terminals; Protein Kinase C; Rats; Rats, Sprague-Dawley; Synaptic Membranes; Synaptic Transmission; Synaptosomes; Tetanus Toxin; Vesicular Glutamate Transport Proteins; Vesicular Transport Proteins | 2008 |
Nanomolar vitamin E alpha-tocotrienol inhibits glutamate-induced activation of phospholipase A2 and causes neuroprotection.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Cell Death; Cell Line, Transformed; Cell Size; Chelating Agents; Dose-Response Relationship, Drug; Down-Regulation; Drug Interactions; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Fatty Acids; Glutamic Acid; Hippocampus; Mice; Neurons; Neuroprotective Agents; Phospholipase A2 Inhibitors; Phospholipases A2; RNA, Small Interfering; Subcellular Fractions; Tocotrienols; Transfection; Vitamin E | 2010 |
Neuroprotection induced by vitamin E against oxidative stress in hippocampal neurons: involvement of TRPV1 channels.
Topics: alpha-Tocopherol; Animals; Calcium; Capsaicin; Cell Death; Cells, Cultured; Diterpenes; Electric Conductivity; Ferrous Compounds; Glutamic Acid; Hippocampus; Neurons; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Sprague-Dawley; Synaptic Transmission; TRPV Cation Channels | 2010 |
Action of 6-amino-3-pyridinols as novel antioxidants against free radicals and oxidative stress in solution, plasma, and cultured cells.
Topics: 1-Methyl-4-phenylpyridinium; alpha-Tocopherol; Animals; Antioxidants; Cytoprotection; Fatty Acids, Unsaturated; Free Radical Scavengers; Glutamic Acid; Lipid Peroxidation; Oxidation-Reduction; Oxidative Stress; Oxidopamine; PC12 Cells; Pyridones; Rats | 2010 |
Cytoprotective effects of vitamin E homologues against glutamate-induced cell death in immature primary cortical neuron cultures: Tocopherols and tocotrienols exert similar effects by antioxidant function.
Topics: alpha-Tocopherol; Animals; Antioxidants; Cell Death; Cerebral Cortex; Glutamic Acid; Glutathione; Neurons; Rats; Tocopherols; Tocotrienols; Vitamin E | 2010 |
Exposure to high glutamate concentration activates aerobic glycolysis but inhibits ATP-linked respiration in cultured cortical astrocytes.
Topics: Adenosine Triphosphate; Aerobiosis; Animals; Aspartic Acid; Astrocytes; Cell Respiration; Cerebral Cortex; Energy Metabolism; Glutamic Acid; Glycolysis; Mitochondria; Oxygen Consumption; Primary Cell Culture; Rats, Sprague-Dawley; Vitamin E | 2014 |
The neuroprotective effects of tocotrienol rich fraction and alpha tocopherol against glutamate injury in astrocytes.
Topics: alpha-Tocopherol; Antioxidants; Astrocytes; Cell Cycle; Cell Death; Cell Line; Cell Survival; Glutamic Acid; Humans; Lipid Peroxidation; Membrane Potential, Mitochondrial; Microscopy, Electron, Scanning; Neuroprotective Agents; Thiobarbituric Acid Reactive Substances; Tocotrienols | 2014 |
Cytoprotective Effect of Tocotrienol-Rich Fraction and α-Tocopherol Vitamin E Isoforms Against Glutamate-Induced Cell Death in Neuronal Cells.
Topics: alpha-Tocopherol; Antioxidants; Apoptosis; Cell Cycle; Cell Death; Cell Line, Tumor; Cell Survival; Free Radicals; Glutamic Acid; Humans; Malondialdehyde; Membrane Potential, Mitochondrial; Microscopy, Electron, Scanning; Neuroblastoma; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Tocotrienols | 2014 |
Large amino acid transporter 1 mediated glutamate modified docetaxel-loaded liposomes for glioma targeting.
Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Calorimetry, Differential Scanning; Cell Line, Tumor; Cell Survival; Docetaxel; Drug Carriers; Drug Liberation; Glioma; Glutamic Acid; Large Neutral Amino Acid-Transporter 1; Liposomes; Male; Mice; Microscopy, Confocal; Microscopy, Electron, Transmission; Taxoids; Vitamin E | 2016 |
Vitamin E-Oligo(methyl diglycol l-glutamate) as a Biocompatible and Functional Surfactant for Facile Preparation of Active Tumor-Targeting PLGA Nanoparticles.
Topics: Animals; Antineoplastic Agents, Phytogenic; Biocompatible Materials; Breast Neoplasms; Cell Survival; Drug Carriers; Drug Delivery Systems; Female; Glutamic Acid; Glycols; Humans; Lactic Acid; Mice; Nanoparticles; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Surface-Active Agents; Tumor Cells, Cultured; Vitamin E; Xenograft Model Antitumor Assays | 2016 |
Ratiometric delivery of two therapeutic candidates with inherently dissimilar physicochemical property through pH-sensitive core-shell nanoparticles targeting the heterogeneous tumor cells of glioma.
Topics: alpha-Tocopherol; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Curcumin; Doxorubicin; Drug Carriers; Drug Delivery Systems; Glioma; Glutamic Acid; Humans; Hydrogen-Ion Concentration; Male; Micelles; Nanoparticles; Neoplastic Stem Cells; Polylysine; Polymers; Rats; Rats, Sprague-Dawley | 2018 |