glutamic acid has been researched along with cysteine in 443 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 52 (11.74) | 18.7374 |
| 1990's | 130 (29.35) | 18.2507 |
| 2000's | 170 (38.37) | 29.6817 |
| 2010's | 77 (17.38) | 24.3611 |
| 2020's | 14 (3.16) | 2.80 |
| Authors | Studies |
|---|---|
| Akamatsu, M; Asao, M; Fujita, T; Iwamura, H | 1 |
| Cha, SH; Chairoungdua, A; Endou, H; Kanai, Y; Kim, DK; Matsuo, H | 1 |
| Brewer, HB; Lohse, P; Rader, DJ | 1 |
| Fonnum, F; Lund-Karlsen, R; Malthe-Sørenssen, D; Oddan, E | 1 |
| Cuénod, M; Do, KQ; Gähwiler, BH; Jiang, ZP; Klancnik, JM | 1 |
| Chevallier, MR; Horák, J; Kotyk, A; Sychrová, H | 1 |
| Choi, SY; Esaki, N; Soda, K; Yoshimura, T | 1 |
| Bonagamba, LG; Machado, BH | 1 |
| Alexiev, U; Greenhalgh, DA; Heyn, MP; Khorana, HG; Otto, H; Subramaniam, S | 1 |
| Lauterburg, BH; Reddy, S; Stofer, B; Witschi, A | 1 |
| Albano, A; Brandi, G; Cantoni, O; Cattabeni, F; Giacomoni, P; Luzzi, L | 1 |
| Dröge, W; Eck, HP; Mihm, S | 2 |
| Pistorio, A | 1 |
| Pangburn, MK | 1 |
| Chen, ZD; Colman, RF; Haeffner-Gormley, L; Zalkin, H | 1 |
| Enger, MD; Kang, YJ | 1 |
| Dunlop, J; Fear, A; Griffiths, R | 1 |
| Dröge, W; Eck, HP; Gmünder, H | 1 |
| Benninghoff, B; Dröge, W; Eck, HP; Gmünder, H; Häcker-Shahin, B; Kriegbaum, H; Mihm, S; Wolf, M | 1 |
| Baran, EJ; Ferrer, EG; Williams, PA | 1 |
| Abriola, DP; MacKerell, AD; Pietruszko, R | 1 |
| Cregar, L; Lin, ZP; Nissim, I; Pleasure, D; Stern, J; Yudkoff, M | 1 |
| Nekliudov, AD | 1 |
| Birnbaum, D; Bode, R; Schmidt, H | 1 |
| Kawaguchi, S; Maita, Y | 1 |
| DuVal, G; Fowler, BA | 1 |
| Elstner, EF; Vogl, G | 1 |
| Eisenstein, E; Markby, DW; Schachman, HK | 1 |
| Ogita, K; Yoneda, Y | 1 |
| Meessen, S; Oesterhelt, D; Otomo, J; Soppa, J; Straub, J; Tittor, J | 1 |
| Damgaard, I; Dunlop, J; Fosmark, H; Grieve, A; Griffiths, R; Schousboe, A | 1 |
| Carlson, HE; Miglietta, JT; Roginsky, MS; Stegink, LD | 1 |
| Dröge, W; Eck, HP; Frey, H | 1 |
| Orten, DK; Owen, MD; Perchellet, JP; Posey, TD; Schneider, BA | 1 |
| Giles, D; Usherwood, PN | 1 |
| Gray, PN; May, PC | 1 |
| Bakker, EP; Booth, IR; Giffard, PM; Kroll, RG; Rowland, GC; Stewart, LM | 1 |
| De La Rosa, J; Hirschberger, LL; Stipanuk, MH | 1 |
| Bannai, S | 1 |
| Erecińska, M; Troeger, MB | 1 |
| Thomson, AM | 1 |
| Bockaert, J; Pin, JP; Recasens, M | 1 |
| Pastuszko, A; Wilson, DF | 1 |
| Gotto, AM; Knapp, RD; Lee, FS; Manoogian, D; Pao, Q; Pownall, HJ; Yang, CY | 1 |
| Bockaert, J; Pin, JP; Recasens, M; Rumigny, JF | 1 |
| Barton, K; Jackson, PJ; Naranjo, CM; Robinson, NJ; Sillerud, LO; Trewhella, J; Watt, K | 1 |
| Abarzua, M; Davis, JA; Rajan, T; Weinberg, JM | 1 |
| Colombo-Zefinetti, G; Pinelli, A; Tofanetti, O; Trivulzio, S | 1 |
| Hartman, FC; Larimer, FW; Smith, HB | 1 |
| Baba, A; Iwata, H; Nishiuchi, Y; Tatsuno, T; Uemura, A | 1 |
| Bannai, S; Ishii, T | 2 |
| Griffith, OW | 1 |
| Cho, ES; Sahyoun, N; Stegink, LD | 1 |
| Bussolati, O; Christensen, HN; Dall'Asta, V; Gazzola, GC; Makowske, M | 1 |
| Gration, KA; Lambert, JJ; Ramsey, RL; Rand, RP; Usherwood, PN | 1 |
| Baba, A; Iwata, H; Yamagami, S | 1 |
| Baba, A; Iwata, H; Lee, E; Tatsuno, T | 1 |
| Hug, DH; Hunter, JK | 1 |
| Lal, DN; Srivastava, AS | 1 |
| Baba, A; Iwata, H; Mizuo, H; Okumura, S | 1 |
| Mangano, RM; Schwarcz, R | 1 |
| Berthon, G; Germonneau, P | 1 |
| Donaldson, PL; Duce, IR; Usherwood, PN | 1 |
| Davidson, FF; Tack, BF; Thomas, ML | 1 |
| Baudry, M; Lynch, G; Maitre, M; Recasens, M; Saadoun, F | 1 |
| Abbott, WA; Bridges, RJ; Meister, A | 1 |
| Baba, A; Iwata, H; Kumagae, Y; Tatsuno, T | 1 |
| Buckthal, DJ; Burns, CL; Hamilton, GA; Main, DE | 1 |
| Jahoor, F; Jaksic, T; Miller, RG | 1 |
| Ahmad, M; Babcock, KK; Chen, X; Johnson, PS; Kumar, KN; Michaelis, EK | 1 |
| Breton, R; Gagnon, Y; Grunberg-Manago, M; Lapointe, J; Pelchat, M; Putzer, H | 1 |
| Eckardt, S; Köhr, G; Lüddens, H; Monyer, H; Seeburg, PH | 1 |
| Johnson, KM; Lonart, G | 2 |
| Balster, RL; Grech, DM; Lunn, WH | 1 |
| Bhattacharyya, A; Deupree, DL; Lee, YH; Schmidt, K; Seah, EC; Tang, XW; Wu, JY | 1 |
| Matsumoto, S; Ohmori, S; Teshigawara, M; Tsuboi, S | 1 |
| Yadid, G; Youdim, MB; Zinder, O | 1 |
| Ammendola, S; Incani, O; Mele, A; Raucci, G; Tramontano, A; Wallace, A | 1 |
| Aukrust, P; Berge, RK; Frøland, SS; Lunden, B; Müller, F; Svardal, AM; Ueland, PM | 1 |
| Eaton, JW; Paller, MS | 1 |
| Bockstette, M; Dröge, W; Mihm, S; Roth, S | 1 |
| Olney, JW | 2 |
| Bannai, S; Miura, K; Sagara, J | 1 |
| Dröge, W; Eck, HP; Fischbach, T; Hartung, S; Kinscherf, R; Murthy, KK; Peterhans, E; Plesker, R; Rouse, S; Stahl-Hennig, C | 1 |
| Betz, H; Kuhse, J; Kuryatov, A; Laube, B | 1 |
| Blumsom, NL; Gardiner, KA; Laming, PR | 1 |
| Baker, JA; Coffman, HR; Poulter, CD; Street, IP | 1 |
| Aoki, N; Hirosawa, S; Toyota, S | 1 |
| Daniel, PC; Derby, CD; Fine, JB; Girardot, MN | 1 |
| Hansen, L; Suzdak, PD; Thomsen, C | 1 |
| Bustin, M; Friedman, FK; Lehn, DA; Postnikov, YV; Robinson, RC; Shiloach, J | 1 |
| Cousins, RB; Gaylor, JD; Grant, MH; Melkonian, AD | 1 |
| Czubak, J; Wróbel, M; Włodek, L | 1 |
| Anderson, KJ; Sandler, DL | 1 |
| Ueda, T; Winter, HC | 1 |
| Girard, M; Grünert, S; Howell, MT; Jackson, RJ; Kean, KM | 1 |
| Arola, L; Salvadó, MJ | 1 |
| Abriola, DP; Blatter, EE; Mukerjee, N; Pietruszko, R | 1 |
| Fuchs, JA; Hanson, C; Li, H; Thomas, GJ; Woodward, C | 1 |
| Olszewski, J; Sparrow, CP | 1 |
| Gehm, BD; Kuo, WL; Perlman, RK; Rosner, MR | 1 |
| Dencher, NA; Heberle, J; Oesterhelt, D; Riesle, J | 1 |
| Maley, F; Reddy, A | 1 |
| Capaldi, RA; Grüber, G | 1 |
| Takemoto, Y | 3 |
| Dekker, EE; Johnson, AR | 1 |
| Lawson, SL; Wakarchuk, WW; Withers, SG | 1 |
| Bona, E; Gilland, E; Hagberg, H; Lehmann, A; Puka-Sundvall, M; Sandberg, M | 1 |
| Kavanaugh, MP; Zerangue, N | 1 |
| Enghild, JJ; Grøn, H; Pizzo, SV; Thøgersen, IB | 1 |
| Czaplinski, K; Peltz, SW; Weng, Y | 1 |
| Eriksson, P; Lehmann, A; Nilsson, M; Puka-Sundvall, M; Sandberg, M | 1 |
| Li, X; Orwar, O; Revesjö, C; Sandberg, M | 1 |
| Alexianu, ME; Appel, SH; Colom, LV; Ionescu, A; La Bella, V; Mohamed, AH | 1 |
| Asano, S; Baba, A; Hashimoto, H; Kishida, Y; Kitanaka, J; Matsuda, T; Takuma, K | 1 |
| Oswald, RE; Wo, ZG | 1 |
| Dringen, R; Hamprecht, B; Kranich, O | 1 |
| Ishimori, K; Morishima, I; Uchida, T; Unno, M | 1 |
| Abbas, AK; Jardemark, K; Lehmann, A; Sandberg, M; Weber, SG | 1 |
| Matsui, TA; Sekiguchi, M; Tagawa, Y; Wada, K; Watase, K | 1 |
| Hagberg, H; Puka-Sundvall, M; Sandberg, M | 1 |
| Heinemann, U; Pannicke, T; Reichelt, W; Stabel-Burow, J; Weichert, H | 1 |
| Fonnum, F; Mathisen, GA; Paulsen, RE | 1 |
| Akaike, A; Fujita, T; Kaneko, S; Kohchiyama, H; Kume, T; Maeda, T; Nishikawa, H; Noda, N | 1 |
| Frandsen, A; Griffiths, R; Malcolm, C; Meredith, C; Ritchie, L; Rumsby, P; Schousboe, A; Scott, M | 1 |
| Dringen, R; Hamprecht, B; Kranich, O; Löschmann, PA | 1 |
| Mokhova, EN; Samartsev, VN | 1 |
| Balashov, SP; Chen, N; Crouch, RK; Ebrey, TG; Imasheva, ES; Menick, DR | 1 |
| Akaike, A; Kaneko, S; Kimura, J; Kochiyama, H; Kume, T; Maeda, T; Shimohama, S | 1 |
| Frillingos, S; Gonzalez, A; Kaback, HR | 1 |
| Burgess, MF; Derby, CD | 1 |
| Petersen, BO; Shuman, S; Wittschieben, J | 1 |
| Bogdanov, A; Marecos, E; Petherick, P; Weissleder, R | 1 |
| Aivazian, D; Ebanks, RO; Farah, CS; Florido, MP; Isaac, L; Isenman, DE; Pangburn, MK; Taniguchi-Sidle, A | 1 |
| Clarke, AJ; Fierobe, HP; McGuire, KA; Mirgorodskaya, E; Roepstorff, P; Svensson, B | 1 |
| Clarke, AJ; Fierobe, HP; Svensson, B; Tull, D | 1 |
| Changchien, L; Lobo, AP; Maley, F; Montfort, WR; Nair, MG; Weichsel, A | 1 |
| Alam, Z; Coombes, N; Steventon, GB; Waring, RH; Williams, AC | 1 |
| Colombari, E; Davisson, RL; Lewis, SJ; Shaffer, RA; Talman, WT | 1 |
| Lu, RC; Qian, F; Wong, A; Wu, G | 1 |
| Kaback, HR; Sun, J; Venkatesan, P; Voss, J | 1 |
| Ameeta, RK; Khan, IM; Krishna, NG; Subray, SH | 1 |
| Burnett, JP; Clark, B; Cockerham, SL; Evans, N; Kingston, AE; Lodge, D; Lowndes, J; Mayne, NG; Tomlinson, R | 1 |
| Casey, JR; Fujinaga, J; Kopito, R; Tang, XB | 1 |
| Frillingos, S; Kaback, HR; Sahin-Tóth, M; Wu, J | 1 |
| Haug, FM; Hjelle, OP; Huster, D; Nagelhus, EA; Ottersen, OP; Reichelt, W | 1 |
| Beers, K; Bottje, WG; Cawthon, D; Evenson, C; McNew, R; Wang, S | 1 |
| Dringen, R; Hamprecht, B | 1 |
| Arthur, JS; Croall, DE; Dutt, P; Elce, JS | 1 |
| Kang, HJ; Lee, ES; Lee, JH; Lee, S; Park, KB; Son, IY; Steinert, PM; Yang, JM; Yeo, UC | 1 |
| Kashina, AS; Kwon, YT; Varshavsky, A | 1 |
| Briddon, A | 1 |
| Akaike, A; Kaneko, S; Katsuki, H; Kume, T | 1 |
| Beck, C; Kuner, T; Sakmann, B; Seeburg, PH; Wollmuth, LP | 1 |
| Arrendondo-Vega, FX; Buckley, R; Conley, ME; El Dahr, J; Hershfield, MS; Notarangelo, LD; Roifman, C; Santisteban, I | 1 |
| Kato, BM; Rubel, EW | 1 |
| Carvalho, Kde M; Fonteles, MC; Neto, UN; Sampaio, HA | 1 |
| Hubbell, WL; Kaback, HR; Zen, KC; Zhao, M | 1 |
| Favilli, F; Iantomasi, T; Vincenzini, MT | 1 |
| Bouchard, BA; Furie, B; Furie, BC | 1 |
| Bravo, J; Bujons, J; Ens, W; Fita, I; Hu, B; Loewen, PC; Maté, MJ; Sevinc, MS; Switala, J | 1 |
| Alberti, L; Bongarzone, I; Borrello, MG; Mondellini, P; Pasini, B; Pierotti, MA; Uggeri, M; Vigano, E | 1 |
| Cheng, FC; Dryhurst, G; Han, J; Yang, Z | 1 |
| Cheng, JY; Wallis, R | 1 |
| Duda, T; Koch, KW; Krishnan, A; Lange, C; Sharma, RK; Venkataraman, V | 1 |
| Alger, BE; Morishita, W | 1 |
| Abdel Ghani, EM; Bhakdi, S; Kehoe, M; Palmer, M; Walev, I; Weis, S | 1 |
| Finbow, ME; Marsh, D; Páli, T | 1 |
| Konings, WN; Lolkema, JS; Slotboom, DJ; Sobczak, I | 1 |
| Choi, HM; Chung, KH | 1 |
| Akhmetov, KZh; Goncharov, LF; Goncharova, ZF; Kelimberdieva, ES; Komissarova, IA; Teĭblium, MM; Zaslavskaia, RM | 1 |
| Dohovics, R; Hermann, A; Janáky, R; Oja, SS; Saransaari, P; Shaw, CA; Varga, V | 1 |
| Bertolini, S; Calandra, S; Cortese, C; Federici, G; Liberatoscioli, L; Motti, C; Rampa, P; Trovatello, G | 1 |
| Palmer, TM; Stiles, GL | 1 |
| Dohovics, R; Hermann, A; Janáky, R; Oja, SS; Saransaari, P; Varga, V | 1 |
| Dove, JE; Klinman, JP; Schwartz, B; Williams, NK | 1 |
| Kaback, HR; Wolin, CD | 1 |
| Aubry, A; Branlant, G; Cobessi, D; Marchal, S; Tête-Favier, F | 1 |
| Jingami, H; Kajimura, N; Nakanishi, S; Nomura, S; Otomo, J; Sekiyama, N; Shimada, Y; Takeshita, T; Tsuji, Y; Usukura, J | 1 |
| Heise, CT; Leamy, CE; Nicholls, JR; Wallis, R | 1 |
| Jayaraman, V; Keesey, R; Madden, DR | 1 |
| Castilla-Cortazar, I; Garcia, M; Pascual, M; Picardi, A; Prieto, J; Quiroga, J; Urdaneta, E | 1 |
| Cordeiro, MN; Diniz, CR; Gomez, MV; Kalapothakis, E; Prado, MA; Reis, HJ; Romano-Silva, MA | 1 |
| Ferry, JG; Tripp, BC | 1 |
| Edwards, HD; Sather, WA; Wu, XS | 1 |
| Braisted, AC; Erlanson, DA; Gordon, EM; Randal, M; Raphael, DR; Stroud, RM; Wells, JA | 1 |
| Nakamoto, RK; Peskova, YB | 1 |
| Chen, C; de Riel, JK; Huang, P; Javitch, JA; Li, J; Liu-Chen, LY; Xu, W | 1 |
| Allan, AM; Galindo, R; Paxton, LL; Queen, SA; Savage, DD | 1 |
| Berg, LJ; Ching, KA; Tsoukas, CD; Yang, WC | 1 |
| Blanchard, JS; Zheng, R | 1 |
| Parkin, G | 1 |
| Engel, PC; Hayden, BM | 1 |
| Goldsmith, PK; Hu, J; Reyes-Cruz, G; Spiegel, AM | 1 |
| Cabrera, N; de Gómez-Puyou, MT; Gómez-Puyou, A; Hernández-Alcantara, G; López-Velazquez, G; Pérez-Montfort, R; Reyes-Vivas, H | 1 |
| Aubry, A; Branlant, G; Cobessi, D; Marchal, S; Rahuel-Clermont, S; Tête-Favier, F | 1 |
| Calabrese, JC; Jordan, DB; Liao, DI; Viitanen, PV; Wawrzak, Z | 1 |
| Denisenko, AD; Tcherkas, YV | 1 |
| Baasov, T; Golan, G; Shallom, D; Shoham, G; Shoham, Y; Shulami, S; Zaide, G; Zolotnitsky, G | 1 |
| Beck, C; Kuner, T; Sakmann, B; Seeburg, PH | 1 |
| Anderson, JW; Fitzgerald, MA; Ugalde, TD | 1 |
| Bangera, MG; McGuire, KA; Olsen, JG; Siggaard-Andersen, M; von Wettstein-Knowles, P | 1 |
| Broad, S; O'Rourke, K; Parker, G; Poole, PS; Robson, RL; Tingey, A; Walshaw, D | 1 |
| Adachi, O; Devreese, B; Duine, JA; Hacisalihoglu, A; Iwabuki, H; Jongejan, JA; Kim, JK; Kuroda, S; Okajima, T; Tanizawa, K; Van Beeumen, J; Vandenberghe, I | 1 |
| Anand, GS; Saxl, RL; Stock, AM | 1 |
| Adachi, O; Devreese, B; Duine, JA; Hacisalihoglu, A; Hirotsu, K; Kim, JK; Kuroda, S; Miyahara, I; Okajima, T; Satoh, A; Tanizawa, K; Van Beeumen, J; Vandenberghe, I | 1 |
| Itou, N; Kawamukai, M; Matsuda, H; Nakagawa, T; Ohta, Y; Shigeru, K; Shimono, K; Tanaka, K; Tsuchiya, A | 1 |
| Powers-Lee, SG; Saeed-Kothe, A | 1 |
| Beck, C; Sobolevsky, AI; Wollmuth, LP | 1 |
| de Wit, JG; den Blaauwen, T; Driessen, AJ; Scheffers, DJ | 1 |
| Dahms, NM; Kim, JJ; Olson, LJ; Zhang, J | 1 |
| Jacobsen, MD; Jorgensen, PL; Pedersen, PA | 1 |
| Ellory, JC; Gibson, JS; Kiessling, K; Roberts, N | 1 |
| Agbas, A; Chen, X; Hong, O; Kumar, KN; Michaelis, EK | 1 |
| Eto, K; Kimura, H; Nagai, Y; Ogasawara, M; Umemura, K | 1 |
| Grunewald, M; Kanner, BI; Menaker, D | 1 |
| Palecz, B | 1 |
| Gonzàlez-Meler, MA; Siedow, JN; Sweet, CR; Umbach, AL | 1 |
| Hikasa, Y; Inaba, M; Matsuki, N; Ono, K; Sato, K; Tamahara, S | 1 |
| An, JY; Davydov, IV; Du, F; Hu, RG; Kashina, AS; Kwon, YT; Seo, JW; Varshavsky, A | 1 |
| Drejer, AH; Schatz, DG; Tsai, CL | 1 |
| Kajikawa, H; Mitsumori, M; Ohmomo, S | 1 |
| Harper, S; Marmorstein, R; Speicher, DW; Yan, Y | 1 |
| Eddins, D; Lyford, LK; McLaughlin, JT; Rosenberg, RL; Sproul, AD | 1 |
| Chen, Y; Dalton, TP; Dieter, MZ; Nebert, DW; Shertzer, HG; Yang, Y | 1 |
| Kang, T; Park, HI; Sang, QX; Suh, Y; Tschesche, H; Zhao, YG | 1 |
| Allison, WS; Bandyopadhyay, S; Huynh, HG; Ren, H; Valder, CR | 1 |
| Rooney, L; Sobolevsky, AI; Wollmuth, LP | 1 |
| Berndt, KD; Chiaraluce, R; Consalvi, V; Ladenstein, R; Lebbink, JH | 1 |
| Adachi, S; Ichihara, K; Lee, DS; Matsunaga, I; Ogura, H; Park, SY; Shiro, Y; Sugimoto, H; Yamada, A | 1 |
| Polgár, L; Sárkány, Z | 1 |
| Barkley, SJ; Droogmans, L; Oudjama, Y; Poulter, CD; Stalon, V; Tricot, C; Wouters, J | 1 |
| Czirják, G; Enyedi, P | 1 |
| Chen, Y; Swanson, RA | 1 |
| Gutkind, JS; Masgrau, R; Pardo, R; Picatoste, F; Sarri, E; Servitja, JM; von Eichel-Streiber, C | 1 |
| Cui, Q; Elstner, M; Frauenheim, T; Karplus, M; Kaxiras, E; Munih, P | 1 |
| Funahashi, HO; Kikuchi, A; Nakagawa, Y; Nakao, A; Sawada, M; Suda, N; Suzuki, M; Takami, Y; Yoshida, S | 1 |
| Eisthen, HL; Park, D | 1 |
| Djordjevic, S; Koshkin, A; Nunn, CM; Ortiz de Montellano, PR | 1 |
| Amler, E; Baumruk, V; Ettrich, R; Hofbauerová, K; Kopecký, V; Krumscheid, R; Kubala, M; Plásek, J; Schoner, W; Teisinger, J | 1 |
| Bieganowski, P; Brenner, C | 1 |
| Clemens, S; Küllertz, G; Maier, T; Yu, C | 1 |
| Li, RA; Tian, Y; Tomaselli, GF; Xiong, W | 1 |
| Ishige, K; Ito, M; Ito, Y; Saito, H; Takagi, N | 1 |
| DIMOND, AE; WAGGONER, PE | 1 |
| BERGERET, B; CHATAGNER, F; FROMAGEOT, C | 1 |
| BERGERET, B; CHATAGNER, F; LABOUESSE, J | 1 |
| MACKAY, D | 1 |
| BLAU, K; DARBRE, A | 1 |
| GERSCHENFELD, HM; LASANSKY, A | 1 |
| Bellamy, HD; Fox, RO; Kaluarachchi, WD; Liu, D; White, MA; Zhao, Y | 1 |
| Dodson, ML; Lloyd, RS; Meador, MG; Rajagopalan, L | 1 |
| Himi, T; Ikeda, M; Morita, I; Nishida, M; Yasuhara, T | 1 |
| Choe, H; Farzan, M; Li, W; Moore, MJ; Wong, SK | 1 |
| Boggs, JM; Hillar, A; Hodges, RS; Tripet, B; Wood, JM; Zoetewey, D | 1 |
| Cho, KB; Pelmenschikov, V; Siegbahn, PE | 1 |
| Ishiko, A; Masunaga, T; Murata, T; Nishikawa, T; Shimizu, H | 1 |
| Hatano-Iwasaki, A; Iwabuchi, M; Ogawa, K; Yanagida, M | 1 |
| Sobolevsky, AI; Wollmuth, LP; Yelshansky, MV | 2 |
| Adams, SR; Deerinck, TJ; Ellisman, MH; Gaietta, G; Garner, CC; Ju, W; Malenka, RC; Morishita, W; Tsien, RY; Tsui, J | 1 |
| Fang, YZ; Lupton, JR; Turner, ND; Wu, G; Yang, S | 1 |
| Allison, WS; Bandyopadhyay, S | 1 |
| Adachi, M; Furuchi, T; Homma, H; Imai, K; Koyama, H; Long, Z; Nakajima, T; Nimura, N; Sekine, M; Shimamoto, K | 1 |
| Bhogal, N; Blaney, FE; Findlay, JB; Ingley, PM; Rees, J | 1 |
| Jayaraman, V | 1 |
| Cheng, Q; Jayaraman, V | 1 |
| Benevides, JM; Bondre, P; Duda, RL; Hendrix, RW; Thomas, GJ | 1 |
| Carlberg, C; Frank, C; Lempiäinen, H; Matilainen, M; Molnár, F | 1 |
| Bulychev, A; Golemi-Kotra, D; Kim, C; Meroueh, SO; Mobashery, S; Stemmler, AJ; Stemmler, TL; Vakulenko, SB | 1 |
| Furie, B; Furie, BC; Grant, MA; Hansson, K; Rigby, AC; Stenflo, J | 1 |
| Botchkareva, AE; Davydov, DR; Halpert, JR; He, YQ; Kumar, S | 1 |
| Knight, JW; Whitaker, BD | 1 |
| Cahoon, RE; Chen, S; Jez, JM | 1 |
| Efremov, RG; Kosinsky, YA; Lutsenko, S; Morgan, CT; Tsivkovskii, R | 1 |
| Fushinobu, S; Koseki, T; Matsuzawa, H; Miyanaga, A; Shoun, H; Wakagi, T | 1 |
| Kwak, EJ; Lim, SI | 1 |
| Forgac, M; Inoue, T; Wang, Y | 1 |
| Hibi, T; Hiratake, J; Kato, H; Kimura, A; Nakatsu, T; Nii, H; Oda, J | 1 |
| Men, L; Wang, Y | 2 |
| Sohal, RS; Toroser, D | 1 |
| Czajkowski, C; McDevitt, RA; Newell, JG | 1 |
| Ishikita, H; Knapp, EW | 1 |
| Drury, J; Narayanaswami, V | 1 |
| Koch, HP; Larsson, HP | 1 |
| Grewer, C; Tao, Z | 1 |
| Beck, SR; Bowden, DW; Burdon, KP; Freedman, BI; Langefeld, CD; Liu, Y; Rich, SS; Wagenknecht, LE | 1 |
| Relyea, HA; Rimkus, S; van der Donk, WA; Wheatley, JL; Woodyer, R | 1 |
| Abali, EE; Banerjee, D; Bertino, JR; Menon, LG; Mishra, PJ; Peters, R; Skacel, N | 1 |
| Hayes, D; McBean, GJ; Rauen, T; Wiessner, M | 1 |
| Huang, HW; Inoue, M; Kataoka, K; Kitagawa, R; Naruse, D; Sakurai, T | 1 |
| Bleecker, ER; Boezen, HM; Jongepier, H; Kauffman, HF; Meurs, H; Meyers, DA; Nelemans, SA; Oostendorp, J; Postma, DS; Volders, H; Zaagsma, J | 1 |
| Bukowska, B | 1 |
| Kang, K; Kinjo, TG; Schnetkamp, PP; Szerencsei, RT; Winkfein, RJ | 1 |
| Akaike, A; Kanki, R; Katsuki, H; Kawai, Y; Kume, T; Nakamizo, T; Sawada, H; Shimohama, S; Sugimoto, H; Yoshida, K | 1 |
| Jong, YJ; Kingston, AE; Kumar, V; O'Malley, KL; Romano, C | 1 |
| Haigler, HT; Isas, JM; Kim, YE; Langen, R | 1 |
| Boggs, JM; Culham, DE; Hillar, A; Vernikovska, YI; Wood, JM | 1 |
| Schuldiner, S; Sharoni, M; Steiner-Mordoch, S | 1 |
| Biaggioni, I; Byrne, DW; Cascorbi, I; Garland, EM; Harris, PA; Jiang, L; Phillips, JA; Robertson, D; Rüdiger, H; Stanton, K; Williams, SM; Winker, R | 1 |
| de Leeuw, E; Ericksen, B; Li, X; Lu, W; Wu, Z | 1 |
| Chait, BT; Fushitani, K; Gorr, TA; Kao, WY; Knapp, JE; Qin, J; Riggs, AF; Riggs, CK; Smith, SS | 1 |
| Müller, M; Zechmann, B; Zellnig, G | 2 |
| Amorós, A; Carrato, A; Hernández, S; Kogevinas, M; Lloreta, J; López-Knowles, E; Malats, N; Real, FX; Serra, C; Tardón, A | 1 |
| Baker, GB; Grant, SL; Hampson, DR; Shulman, Y; Tibbo, P | 1 |
| Cater, MA; La Fontaine, S; Mercer, JF | 1 |
| Akaike, A; Fujii, T; Katsuki, H; Kume, T; Niidome, T; Okabe, S; Sugimoto, H; Sugimoto, M; Takada-Takatori, Y | 1 |
| Armstrong, N; Beich-Frandsen, M; Gouaux, E; Jasti, J | 1 |
| Gao, YG; Hu, HY; Ouyang, N; Xia, ZX | 1 |
| Kuroki, Y; Matsushima, N; Mitsuzawa, H; Nishitani, C; Sano, H; Shimizu, T | 1 |
| Antoine, M; Boschi-Muller, S; Branlant, G; Gand, A | 1 |
| Lerma, J; Priel, A; Selak, S; Stern-Bach, Y | 1 |
| Giovannini, C; Grande, S; Guidoni, L; Luciani, AM; Palma, A; Rosi, A; Sapora, O; Viti, V | 1 |
| Fernandes, PA; Ramos, MJ; Sousa, SF | 1 |
| Chiu, WC; Huang, SW; Hung, CL; Hwang, JK; Liu, JH; Wang, WC | 1 |
| Hellmer, H; Klimacek, M; Nidetzky, B | 1 |
| Dressler, DH; Mastai, Y | 1 |
| Burghardt, I; Cederbaum, LS; Gromov, EV; Köppel, H | 1 |
| Prodromou, ML; Sobolevsky, AI; Wollmuth, LP; Yelshansky, MV | 1 |
| Aufenvenne, K; Bombosch, B; Hintze, V; Höwel, M; Stöcker, W; Wermter, C; Yiallouros, I | 1 |
| Kanner, BI; Teichman, S | 1 |
| Ferguson, SJ; Mavridou, DA; Redfield, C; Stevens, JM | 1 |
| Berthomieu, C; Houée-Levin, C; Mathé, C; Mattioli, TA; Nivière, V; Tremey, E; Weill, CO | 1 |
| Braun, V; Herrmann, C | 1 |
| Colbert, RA; Granfors, K; Heiskanen, KM; Penttinen, MA; Sahlberg, AS; Sistonen, L | 1 |
| Fraser, ME; Rochet, JC; Tammam, SD | 1 |
| Banjac, A; Bannai, S; Bornkamm, GW; Conrad, M; Daniel, PT; Issels, RD; Kölle, P; Perisic, T; Sato, H; Seiler, A; Tschoep, K; Weiss, N | 1 |
| Jones, AK; Sattelle, DB | 1 |
| Banerjee, R; Ciborowski, P; Garg, SK; Gendelman, HE; Glanzer, JG; Kadiu, I; Nordgren, T; Reynolds, AD | 1 |
| Clarke, CE; Mathie, A; Vandenberg, JI; Veale, EL; Wyse, K | 1 |
| Hasim, S; Lakshminarasimhan, M; Pozharski, E; Remington, BC; Wilson, MA; Witt, AC | 1 |
| Abe, M; Abe, S; Erker, G; Hikage, T; Niemeyer, J; Takezawa, Y; Ueno, T; Watanabe, Y | 1 |
| Lewerenz, J; Lozano, C; Maher, P; Torres, JL | 1 |
| Chen, Y; Xing, G; Zhang, J; Zhao, Y | 1 |
| Chen, J; Du, G; Liang, G; Liao, X | 1 |
| Acher, F; Alarcon, K; Bertrand, HO; Krzaczkowski, L; Le Goff, A; Leonetti, M; Mony, L; Neyton, J; Paoletti, P | 1 |
| Acton, TB; Aramini, JM; Chen, CX; Fischer, M; Honig, B; Maglaqui, M; Montelione, GT; Nair, R; Nwosu, C; Owens, LA; Rossi, P; Rost, B; Xiao, R | 1 |
| Evans, RJ; Wen, H | 1 |
| Ahmad, R; Blackinton, J; Cookson, MR; Greggio, E; Lakshminarasimhan, M; Raza, AS; Thomas, KJ; Wilson, MA | 1 |
| Lim, HH; Miller, C | 1 |
| Basak, A; Chen, A; Coderre, E; Hameed, S; Ouardouz, M; Rehak, R; Stys, PK; Trapp, BD; Yin, X; Zamponi, GW | 1 |
| Oomens, J; Redlich, B; Steill, JD | 1 |
| Adolph, HW; Heinz, U; Hemmingsen, L; Kiefer, M | 1 |
| Fisk, M; Goodenowe, DB; Heath, D; Jin, W; Kavianpour, A; Khine Su-Myat, K; Lu, Y; Pastural, E; Ritchie, S; Wood, PL | 1 |
| Bolger, MB; Davies, DL; Haworth, IS; Kulkarni, AA; Xu, L | 1 |
| Crespo-López, ME; do Nascimento, JL; Herculano, AM; Oliveira, KR | 1 |
| Choi, JG; Lee, SA; Zuo, Z | 1 |
| Boscherini, F; Cotton, NP; Francia, F; Giachini, L; Jackson, JB; Venturoli, G; Veronesi, G; Whitehead, SJ | 1 |
| Bachhawat, AK; Kumar, A | 1 |
| Dementiev, A; Gettins, PG; Huang, X; Olson, ST | 1 |
| Becker, K; Fritz-Wolf, K; Hipp, M; Jortzik, E; Rahlfs, S; Sturm, N | 1 |
| Askew, C; Davis, NG; Hayden, MR; Huang, K; Kang, MH; Kang, R; Sanders, SS; Wan, J | 1 |
| Chuttani, K; Kakkar, D; Kaul, A; Mishra, AK; Singh, H; Tiwari, AK | 1 |
| Beato, VM; Mansilla, F; Montaño, A; Orgaz, F | 1 |
| Altai, M; Graslund, T; Hofstrom, C; Orlova, A; Tolmachev, V; Wangsell, F | 1 |
| Aasheim, ET; Birkeland, KI; Bøhmer, T; Diep, LM; Elshorbagy, AK; Mala, T; Olbers, T; Refsum, H; Søvik, TT; Valdivia-Garcia, M | 1 |
| Aghasadeghi, MR; Ardestani, MS; Barghi, Z; Cohan, RA; Hedayati, MH; Inanlou, DN; Khanahmad, H; Madadkar-Sobhani, A; Norouzian, D; Roohvand, F | 1 |
| Borker, P; Prodromou, ML; Salussolia, CL; Wollmuth, LP | 1 |
| Accardi, CJ; Hu, X; Jones, DP; Kim, SB; Miller, NG; Park, Y; Zhao, T; Ziegler, TR | 1 |
| Koffler, BE; Maier, R; Zechmann, B | 1 |
| Baghel, GS; Dessingou, J; Mitra, A; Rao, CP; Tabbasum, K | 1 |
| Shang, F; Sun, J; Tan, T; Wang, M; Wang, Z; Xue, F | 1 |
| Aoyama, K; Kikuchi-Utsumi, K; Kinoshita, C; Kiyonari, H; Matsumura, N; Nakaki, T; Shioi, G; Tanaka, K; Wang, F; Watabe, M | 1 |
| De Vos, D; Savvides, SN; Stout, J; Vergauwen, B | 1 |
| Ashida, H; Gohda, J; Inoue, J; Kim, M; Kobayashi, T; Koyama, T; Mimuro, H; Mizushima, T; Nagai, S; Ogawa, M; Oyama, A; Sanada, T; Sasakawa, C; Shibata, Y; Suzuki, M | 1 |
| Lee, EJ; Patil, BS; Yoo, KS | 1 |
| Frias, JA; Goblirsch, BR; Wackett, LP; Wilmot, CM | 1 |
| Ferro, AS; Overocker, JJ; Pfau, JC; Roe, J; Seib, T | 1 |
| Mozziconacci, O; Schöneich, C; Williams, TD | 1 |
| Arai, S; Blaber, M; Kurihara, K; Kuroki, R; Morimoto, S; Shoyama, Y; Takeuchi, A; Tamada, T; Taura, F | 1 |
| Dessingou, J; Pathak, RK; Rao, CP | 1 |
| Aghera, N; Dasgupta, I; Udgaonkar, JB | 1 |
| Al-Harthi, L; Henderson, LJ; Major, EO; Monaco, MC; Sharma, A | 1 |
| Fan, J; Kennedy, MA; Morozov, VA; Mukherjee, M; Ni, S; Ogawa, MY; Zaytsev, DV; Zhu, X | 1 |
| Alloisio, S; Cervetto, C; Frattaroli, D; Gavazzo, P; Marcoli, M; Maura, G; Mazzotta, MC; Milanese, M; Nobile, M; Passalacqua, M | 1 |
| Amara, P; Fontecilla-Camps, JC; Mouesca, JM | 1 |
| Carattino, MD; Della Vecchia, MC; Rued, AC | 1 |
| Seidlitz, EP; Singh, G; Ungard, RG | 1 |
| Aoyama, K; Nakaki, T | 1 |
| Alajaji, M; Bowers, MS; Damaj, MI; Knackstedt, L | 1 |
| Ambrosio, AL; Barbosa, JA; Benedetti, CE; Brasil de Souza, Tde A; Campos, BM; Domingues, MN; Murakami, MT; Paes Leme, AF; Perez, CA; Sforça, ML; Whittaker, SB; Zeri, AC | 1 |
| Chaffotte, AF; Dupret, JM; Haouz, A; Kubiak, X; Li de la Sierra-Gallay, I; Pluvinage, B; Rodrigues-Lima, F; Weber, P | 1 |
| Blachowicz, L; Ghisi, V; Lau, AY; Plested, AJ; Roux, B; Salazar, H | 1 |
| Cowan, DA; Gumbart, JC; Hunter, R; Kimani, SW; Sewell, BT; Varsani, A; Venter, GA; Weber, BW | 1 |
| Ankonina, G; Brif, A; Drathen, C; Pokroy, B | 1 |
| Barford, D; Bineva, G; Cronin, N; Dodd, RB; Hanrahan, SJ; Iwata, S; Kulkarni, K; Manolaridis, I; Ogasawara, S; Reilly, NO; Thompson, AJ; Zhang, Z | 1 |
| Pecoraro, VL; Zastrow, ML | 1 |
| Arakawa, T; Beckham, GT; Fujita, K; Fushinobu, S; Ishiwata, A; Ito, T; Ito, Y; Kaeothip, S; Kim, S; Saikawa, K; Wakagi, T | 1 |
| Qu, S; Zhang, X; Zhang, Y | 1 |
| Cookson, MR; Hauser, DN; Milkovic, NM; Prahlad, J; Wilson, MA | 1 |
| Li, M; Sobolevsky, AI; Yelshanskaya, MV | 1 |
| Kawakami, R; Ohshima, T; Sakuraba, H | 1 |
| Bobovská, A; Kóňa, J; Tvaroška, I | 1 |
| Kanda, H; Kumagai, Y; Shinkai, Y | 1 |
| Amara, SG; Divito, CB; Torres-Salazar, D; Watts, SD | 1 |
| Hirakawa, K; Maeda, K; Nagahara, H; Ohtani, H; Shibutani, M; Sugano, K | 1 |
| Guitart, K; Kleene, R; Loers, G; Schachner, M | 1 |
| Lingle, CJ; Xia, XM; Zhou, Y | 1 |
| Akanuma, S; Hosoya, K; Kubo, Y; Zakoji, N | 1 |
| Jayasena, DD; Jo, C; Jung, S; Kim, HJ; Nam, KC; Yong, HI | 1 |
| Daikhin, Y; Doulias, PT; Evans, P; Horyn, O; Ischiropoulos, H; Jackson, JG; Krizman, EN; Nissim, I; Raju, K; Robinson, MB; Sharp, KA; Yudkoff, M | 1 |
| Hughes, BA; Woodward, JJ | 1 |
| Geck, RC; Toker, A | 1 |
| Li, W; Li, Z; Wang, D; Wu, H; Yang, J; Ye, Q | 1 |
| Blount, P; Gao, Y; Iscla, I; Li, H; Wang, J; Wray, R | 1 |
| Backus, KM; Briggs, KJ; Cao, S; Clardy, J; Cravatt, BF; Gerfen, GJ; Kaelin, WG; Koivunen, P; Olenchock, BA; Patel, H; Richardson, AL; Signoretti, S; Witkiewicz, AK; Zhang, Q | 1 |
| Albano, R; Lobner, D | 1 |
| Chen, S; Huang, H; Li, J; Nomura, CT; Wan, X; Wang, C; Wang, Q; Zheng, H | 1 |
| Godin, JP; Guiraud, SP; Jia, W; Kussmann, M; Martin, FP; Nydegger, A; Su, MM; Xie, GX | 1 |
| Charmantray, F; de Bérardinis, V; Gefflaut, T; Heuson, E; Petit, JL | 1 |
| Asara, JM; Geck, RC; Ghisolfi, L; Lien, EC; Toker, A | 1 |
| Kong, Q; Wang, Y; Xu, C; Yu, J; Zhang, L | 1 |
| Qu, S; Zhang, W; Zhang, X | 1 |
| Kimura, H; Kimura, Y; Shibuya, N | 1 |
| Chen, H; Feng, Z; Leng, C; Liu, G; Lv, X; Qiao, Y; Sun, J; Zhang, Y | 1 |
| Bangash, SAK; Joshi, NC; Leustek, T; Meyer, AJ; Zheng, ZL | 1 |
| Salyha, N; Salyha, Y | 1 |
| Gould, RL; Pazdro, R | 1 |
| Higuchi, Y; Hirota, S; Mao, ZW; Nishikawa, K; Tai, H | 1 |
| Huang, L; Lian, J; Liu, W; Xu, Z; Zhu, X | 1 |
| Greenberg, ML; Ji, J; Li, Y; Patil, VA | 1 |
| Cui, H; Hayat, K; Ho, CT; Hussain, S; Sun, F; Tahir, MU; Xu, M; Zhan, H; Zhang, X | 1 |
| Delfarah, A; Graham, NA; Joly, JH; Parrish, S; Phung, PS | 1 |
| Ansari, MZ; Swaminathan, R | 1 |
| Cao, HY; Chen, XL; Chen, Y; Li, CY; Li, PY; Su, HN; Wang, P; Wang, Y; Wang, YJ; Zhang, Y; Zhang, YZ | 1 |
| Ghosh, S; Malik, C | 1 |
| Huettner, JE; Wilding, TJ | 1 |
| Echavarri-Erasun, C; Fajardo, AS; Legrand, P; Martin, L; Nicolet, Y; Payá-Tormo, LA; Pellicer Martı Nez, MT; Rubio, LM; Vernède, X | 1 |
| Cerqueira, NMFSA; Silva Teixeira, CS; Sousa, SF | 1 |
| Hirata, K; Hirata, Y; Matsuura, H; Muraoka, M; Nagano, K; Ohno, M; Tateishi, M | 1 |
| Biggin, PC; Deme, JC; Kolokouris, D; Kuteyi, G; Lea, SM; Newstead, S; Parker, JL | 1 |
| Hammes-Schiffer, S; Reinhardt, CR; Zhong, J | 1 |
| Chen, X; Ge, T; He, Z; Wang, J; Yuan, H; Zhang, L | 1 |
| Hong, SB; Li, Z; Quan, J; Tan, J; Wu, M; Zang, Y; Zhao, Y; Zheng, W; Zhu, Z | 1 |
| Gao, Y; Liu, H; Sun, M; Wang, S; Zhu, J | 1 |
15 review(s) available for glutamic acid and cysteine
| Article | Year |
|---|---|
HIV-induced cysteine deficiency and T-cell dysfunction--a rationale for treatment with N-acetylcysteine.
Topics: Acetylcysteine; Cysteine; Cystine; Glutamates; Glutamic Acid; Glutathione; HIV; HIV Infections; Humans; Hydrogen Peroxide; Oxidation-Reduction; Oxygen; Palliative Care; Superoxides; T-Lymphocytes | 1992 |
Immunomodulatory action of eicosanoids and other small molecular weight products of macrophages.
Topics: Cysteine; Cytokines; Dinoprostone; Glutamates; Glutamic Acid; Immunity, Cellular; Immunologic Deficiency Syndromes; Lactates; Lactic Acid; Lymphokines; Macrophages; Molecular Weight; Ornithine; Prostaglandins; T-Lymphocytes | 1991 |
[Aliphatic alpha-amino acids as biologically active compounds].
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Cysteine; Glutamates; Glutamic Acid; Glycine; Homeostasis; Humans | 1990 |
Excitotoxins in foods.
Topics: Amino Acids, Diamino; Animals; Aspartame; beta-Alanine; Cyanobacteria Toxins; Cysteine; Foodborne Diseases; Glutamic Acid; Humans; Kainic Acid; Neurotoxins; Receptors, N-Methyl-D-Aspartate | 1994 |
Cys-scanning mutagenesis: a novel approach to structure function relationships in polytopic membrane proteins.
Topics: Alkylation; Amino Acid Sequence; Antibodies, Monoclonal; Bacterial Proteins; Binding Sites; Catalytic Domain; Cysteine; Escherichia coli; Escherichia coli Proteins; Glutamic Acid; Ion Transport; Membrane Proteins; Membrane Transport Proteins; Models, Molecular; Molecular Sequence Data; Monosaccharide Transport Proteins; Mutagenesis, Site-Directed; Protein Conformation; Protein Structure, Secondary; Protons; Recombinant Fusion Proteins; Structure-Activity Relationship; Symporters | 1998 |
Synthetic analogs of zinc enzymes.
Topics: Alcohol Dehydrogenase; Amidohydrolases; Amino Acid Motifs; Aminopeptidases; Animals; Aspartic Acid; Bacterial Proteins; Bicarbonates; Binding Sites; Carbonic Anhydrases; Carboxypeptidases; Catalysis; Cations, Divalent; Cysteine; Dihydroorotase; DNA Repair; Enzymes; Escherichia coli Proteins; Glutamic Acid; Histidine; Ligands; Liver; Matrix Metalloproteinases; Metalloproteins; Models, Chemical; Molecular Structure; N-Acetylmuramoyl-L-alanine Amidase; Nitrates; O(6)-Methylguanine-DNA Methyltransferase; Porphobilinogen Synthase; Spectrum Analysis; Thermolysin; Transcription Factors; Water; Zinc | 2001 |
Glutathione metabolism and its implications for health.
Topics: Cysteine; Glutamic Acid; Glutathione; Glycine; Health; Humans | 2004 |
Excitatory neurotoxins as food additives: an evaluation of risk.
Topics: Adult; Age Factors; Aspartame; Aspartic Acid; Blood-Brain Barrier; Child; Cysteine; Dietary Supplements; Electrophysiology; Excitatory Amino Acids; Female; Food Analysis; Glutamic Acid; Humans; Neurotoxicity Syndromes; Neurotoxins; Pregnancy; Protein Hydrolysates; Risk Assessment; Risk Factors; Species Specificity | 1981 |
[Glutathione: its biosynthesis, induction agents and concentrations in selected diseases].
Topics: Animals; Cysteine; Cystine; Glutamic Acid; Glutathione; Glycine; Humans; Male; Neoplasms | 2004 |
Oxidative stress and cancer pain.
Topics: Bone and Bones; Bone Neoplasms; Breast Neoplasms; Cysteine; Female; Glutamic Acid; Humans; Nociceptive Pain; Oxidative Stress; Reactive Oxygen Species | 2013 |
Neuroprotective properties of the excitatory amino acid carrier 1 (EAAC1).
Topics: Animals; Antioxidants; Central Nervous System; Cysteine; Excitatory Amino Acid Transporter 3; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Glutathione; Humans; Mice; Neuroprotective Agents; Synaptic Transmission | 2013 |
Designing hydrolytic zinc metalloenzymes.
Topics: Binding Sites; Carbonic Anhydrases; Catalysis; Catalytic Domain; Crystallography, X-Ray; Cysteine; Glutamic Acid; Histidine; Hydrolysis; Metalloproteins; Models, Molecular; Protein Binding; Protein Engineering; Protein Structure, Secondary; Zinc; Zinc Fingers | 2014 |
S-mercuration of cellular proteins by methylmercury and its toxicological implications.
Topics: Animals; Arginase; Calcium; Cysteine; Glutamic Acid; Glutathione Transferase; Humans; L-Iditol 2-Dehydrogenase; Membrane Proteins; Methylmercury Compounds; Microtubules; Oxidative Stress; Protein Binding; Sulfhydryl Compounds; Superoxide Dismutase; Tubulin | 2014 |
Nonessential amino acid metabolism in breast cancer.
Topics: Animals; Arginine; Breast Neoplasms; Cysteine; Diet Therapy; Female; Food Deprivation; Glutamic Acid; Glutamine; Glycine; Humans; Metabolic Networks and Pathways; Proline; Serine | 2016 |
Impact of Supplementary Amino Acids, Micronutrients, and Overall Diet on Glutathione Homeostasis.
Topics: Amino Acids; Animals; Antioxidants; Ascorbic Acid; Cysteine; Diet; Dietary Supplements; Glutamic Acid; Glutathione; Glycine; Homeostasis; Humans; Micronutrients; Oxidative Stress; Vitamin E | 2019 |
2 trial(s) available for glutamic acid and cysteine
| Article | Year |
|---|---|
[Comparative efficacy of combined therapy with preductal and amino acid composition in elderly patients with coronary heart disease and class II-III angina].
Topics: Aged; Aged, 80 and over; Angina Pectoris; Cysteine; Drug Therapy, Combination; Echocardiography; Electrocardiography, Ambulatory; Female; Glutamic Acid; Glycine; Hemodynamics; Humans; Male; Middle Aged; Myocardial Ischemia; Treatment Outcome; Trimetazidine; Vasodilator Agents | 1999 |
Effect of bariatric surgery on sulphur amino acids and glutamate.
Topics: Adult; Amino Acids, Sulfur; Bariatric Surgery; Body Mass Index; Cysteine; Duodenum; Female; gamma-Glutamyltransferase; Gastric Bypass; Glutamic Acid; Glutathione; Humans; Male; Middle Aged; Obesity, Morbid; Taurine; Weight Loss; Young Adult | 2011 |
426 other study(ies) available for glutamic acid and cysteine
| Article | Year |
|---|---|
Quantitative structure-activity relationships of the bitter thresholds of amino acids, peptides, and their derivatives.
Topics: Amino Acids; Humans; Mathematics; Peptides; Structure-Activity Relationship; Taste | 1987 |
Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters.
Topics: Amino Acid Sequence; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Animals; Anion Transport Proteins; Bacterial Proteins; Carrier Proteins; Cloning, Molecular; Escherichia coli Proteins; Female; Intestine, Small; Kinetics; Levodopa; Mice; Molecular Sequence Data; Oocytes; Phenylalanine; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tryptophan; Tyrosine; Xenopus laevis | 2001 |
Heterozygosity for apolipoprotein E-4Philadelphia(Glu13----Lys, Arg145----Cys) is associated with incomplete dominance of type III hyperlipoproteinemia.
Topics: Adolescent; Adult; Aged; Apolipoprotein E3; Apolipoprotein E4; Apolipoproteins E; Arginine; Child; Cysteine; DNA; Electrophoresis, Polyacrylamide Gel; Female; Genes, Dominant; Glutamates; Glutamic Acid; Heterozygote; Homozygote; Humans; Hyperlipoproteinemia Type III; Lysine; Male; Middle Aged; Pedigree; Phenotype; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length | 1992 |
Changes in neurotransmitter parameters in the brain induced by L-cysteine injections in the young rat.
Topics: Acetylcholine; Animals; Brain Chemistry; Choline O-Acetyltransferase; Cysteine; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamates; Glutamic Acid; Injections, Subcutaneous; Neurotransmitter Agents; Rats; Rats, Inbred Strains | 1992 |
Release of endogenous amino acids, including homocysteic acid and cysteine sulphinic acid, from rat hippocampal slices evoked by electrical stimulation of Schaffer collateral-commissural fibres.
Topics: Amino Acids; Animals; Aspartic Acid; Cysteine; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Hippocampus; Homocysteine; In Vitro Techniques; Kinetics; Male; Methionine; Nerve Fibers; Neurotransmitter Agents; Pyramidal Tracts; Rats; Rats, Inbred Strains; Time Factors | 1992 |
Thialysine-resistant mutants and uptake of lysine in Schizosaccharomyces pombe.
Topics: Arginine; Biological Transport, Active; Cysteine; Drug Resistance, Microbial; Glutamates; Glutamic Acid; Kinetics; Leucine; Lysine; Schizosaccharomyces | 1992 |
Reaction mechanism of glutamate racemase, a pyridoxal phosphate-independent amino acid racemase.
Topics: Amino Acid Isomerases; Bacterial Proteins; Cysteine; Deuterium; Enzyme Activation; Glutamates; Glutamic Acid; Kinetics; Magnetic Resonance Spectroscopy; Pediococcus; Pyridoxal Phosphate; Sulfhydryl Compounds; Tritium | 1992 |
Microinjection of S-nitrosocysteine into the nucleus tractus solitarii of conscious rats decreases arterial pressure but L-glutamate does not.
Topics: Animals; Blood Pressure; Brain; Cysteine; Glutamates; Glutamic Acid; Heart Rate; Male; Microinjections; Nitric Oxide; Rats; Rats, Wistar; S-Nitrosothiols | 1992 |
Effect of introducing different carboxylate-containing side chains at position 85 on chromophore formation and proton transport in bacteriorhodopsin.
Topics: Amino Acid Sequence; Aspartic Acid; Bacteriorhodopsins; Cysteine; Glutamates; Glutamic Acid; Halobacterium salinarum; Iodoacetamide; Iodoacetates; Iodoacetic Acid; Kinetics; Mutagenesis, Site-Directed; Protons; Recombinant Proteins | 1992 |
The systemic availability of oral glutathione.
Topics: Administration, Oral; Adult; Biological Availability; Cysteine; Female; Glutamates; Glutamic Acid; Glutathione; Humans; Male; Middle Aged | 1992 |
Differential effect of the amino acid cystine in cultured mammalian and bacterial cells exposed to oxidative stress.
Topics: Animals; Cell Division; Cell Survival; CHO Cells; Cricetinae; Cysteine; Cystine; Escherichia coli; Glutamates; Glutamic Acid; Glycine; Hydrogen Peroxide | 1992 |
[Observations on viral hepatitis in community medicine].
Topics: Biochemical Phenomena; Biochemistry; Cysteine; Glutamates; Glutamic Acid; Hepatitis, Viral, Human; Humans; Interferons; Neurotransmitter Agents; Ornithine; Pyruvates; Pyruvic Acid | 1992 |
Spontaneous thioester bond formation in alpha 2-macroglobulin, C3 and C4.
Topics: alpha-Macroglobulins; Complement C3; Complement C4; Cysteine; Esters; Glutamates; Glutamic Acid; Hot Temperature; Humans; Protein Conformation; Sulfhydryl Compounds | 1992 |
Evaluation of cysteine 283 and glutamic acid 284 in the coenzyme binding site of Salmonella typhimurium glutamate dehydrogenase by site-directed mutagenesis and reaction with the nucleotide analogue 2-[4-bromo-2,3-dioxobutyl)thio)-1,N6-ethenoadenosine 2',
Topics: Adenosine Diphosphate; Affinity Labels; Amino Acid Sequence; Base Sequence; Binding Sites; Cysteine; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Genes, Bacterial; Glutamate Dehydrogenase; Glutamates; Glutamic Acid; Molecular Sequence Data; Mutagenesis, Site-Directed; Plasmids; Salmonella typhimurium | 1991 |
Increased glutathione levels in quiescent, serum-stimulated NRK-49F cells are associated not with a response to growth factors but with nutrient repletion.
Topics: Animals; Blood; Buthionine Sulfoximine; Cell Division; Cell Line; Culture Media; Cysteine; DNA; Epidermal Growth Factor; Glutamates; Glutamic Acid; Glutathione; Growth Substances; Interphase; Methionine Sulfoximine | 1991 |
Glutamate uptake into synaptic vesicles--inhibition by sulphur amino acids.
Topics: Animals; Biological Transport; Cerebral Cortex; Cysteine; Glutamates; Glutamic Acid; Homocysteine; Kinetics; Male; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Stereoisomerism; Structure-Activity Relationship; Synaptic Vesicles | 1991 |
Low membrane transport activity for cystine in resting and mitogenically stimulated human lymphocyte preparations and human T cell clones.
Topics: Alanine; Arginine; Biological Transport; Cell Division; Cell Membrane; Cells, Cultured; Clone Cells; Cysteine; Cystine; Glutamates; Glutamic Acid; HIV Seropositivity; Humans; Lymphocytes; Methionine; Mitogens; Phytohemagglutinins; T-Lymphocytes | 1991 |
A spectrophotometric study of the VO(2+)-glutathione interactions.
Topics: Amino Acids; Chemical Phenomena; Chemistry, Physical; Crystallization; Cysteine; Glutamates; Glutamic Acid; Glutathione; Glycine; Hydrogen-Ion Concentration; Spectrophotometry; Spectrophotometry, Infrared; Vanadates | 1991 |
Correlation of loss of activity of human aldehyde dehydrogenase with reaction of bromoacetophenone with glutamic acid-268 and cysteine-302 residues. Partial-sites reactivity of aldehyde dehydrogenase.
Topics: Acetophenones; Affinity Labels; Aldehyde Dehydrogenase; Amino Acid Sequence; Chromatography, High Pressure Liquid; Cysteine; Glutamates; Glutamic Acid; Humans; Isoenzymes; Molecular Sequence Data; Peptide Fragments; Trypsin | 1990 |
Glutathione turnover in cultured astrocytes: studies with [15N]glutamate.
Topics: Amino Acids; Animals; Astrocytes; Cells, Cultured; Cysteine; Glutamates; Glutamic Acid; Glutathione; Nitrogen Isotopes | 1990 |
Inhibition of alpha-aminoadipate-semialdehyde dehydrogenase from Trichosporon adeninovorans by lysine and lysine analogues.
Topics: Aldehyde Oxidoreductases; Binding, Competitive; Cysteine; Glutamates; Glutamic Acid; Hydroxylysine; Kinetics; L-Aminoadipate-Semialdehyde Dehydrogenase; Lysine; Mitosporic Fungi; Trichosporon | 1990 |
Amino acid sequence of cadmium-binding peptide induced in a marine diatom, Phaeodactylum tricornutum.
Topics: Amino Acid Sequence; Cadmium; Cysteine; Dansyl Compounds; Eukaryota; Glutamates; Glutamic Acid; Glutathione; Glycine; Metallothionein; Molecular Sequence Data; Phytoplankton | 1990 |
Preliminary purification and characterization studies of a low molecular weight, high affinity cytosolic lead-binding protein in rat brain.
Topics: Animals; Aspartic Acid; Blotting, Western; Brain Chemistry; Carrier Proteins; Chromatography, Gel; Chromatography, Ion Exchange; Cysteine; Cytosol; Electrophoresis, Polyacrylamide Gel; Glutamates; Glutamic Acid; Lead; Liver; Male; Molecular Weight; Rabbits; Rats; Rats, Inbred Strains | 1989 |
Diesel soot particles catalyze the production of oxy-radicals.
Topics: Air Pollutants; Carbon; Carotenoids; Catalysis; Cysteine; Ethylenes; Free Radicals; Gasoline; Glutamates; Glutamic Acid; Hydrogen Peroxide; Light; Linolenic Acids; Oxidants, Photochemical; Oxidation-Reduction; Petroleum; Polyenes | 1989 |
Changes in stability and allosteric properties of aspartate transcarbamoylase resulting from amino acid substitutions in the zinc-binding domain of the regulatory chains.
Topics: Allosteric Regulation; Amino Acids; Asparagine; Aspartate Carbamoyltransferase; Binding Sites; Catalysis; Cysteine; Drug Stability; Escherichia coli; Glutamates; Glutamic Acid; Macromolecular Substances; Mutation; Protein Conformation; Salmonella typhimurium; Structure-Activity Relationship; Zinc | 1989 |
Selective potentiation by L-cysteine of apparent binding activity of [3H]glutathione in synaptic membranes of rat brain.
Topics: Amino Acids; Animals; Brain; Cysteine; Glutamates; Glutamic Acid; Glutathione; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Synaptic Membranes | 1989 |
Bacteriorhodopsin mutants of Halobacterium sp. GRB. II. Characterization of mutants.
Topics: Amino Acid Sequence; Asparagine; Aspartic Acid; Bacteriorhodopsins; Base Sequence; Cloning, Molecular; Cysteine; Genes, Bacterial; Glutamates; Glutamic Acid; Glycine; Halobacterium; Molecular Sequence Data; Mutation; Protein Conformation; Tryptophan; Tyrosine | 1989 |
Inhibition by excitatory sulphur amino acids of the high-affinity L-glutamate transporter in synaptosomes and in primary cultures of cortical astrocytes and cerebellar neurons.
Topics: Amino Acids; Animals; Aspartic Acid; Astrocytes; Cerebellum; Cerebral Cortex; Cysteine; Glutamates; Glutamic Acid; Mice; Molecular Conformation; Neurotransmitter Uptake Inhibitors; Stereoisomerism; Synaptosomes | 1989 |
Stimulation of pituitary hormone secretion by neurotransmitter amino acids in humans.
Topics: Adrenocorticotropic Hormone; Adult; Amino Acids; Aspartic Acid; Cysteine; Female; Glutamates; Glutamic Acid; Growth Hormone; Humans; Hydrocortisone; Luteinizing Hormone; Male; Neurotransmitter Agents; Pituitary Gland; Pituitary Hormones; Prolactin; Taurine; Thyrotropin | 1989 |
Elevated plasma glutamate concentrations in HIV-1-infected patients may contribute to loss of macrophage and lymphocyte functions.
Topics: Cysteine; Glutamates; Glutamic Acid; HIV Infections; HIV-1; Humans; In Vitro Techniques; Lymphocyte Activation; Lymphocytes; Macrophages | 1989 |
Inhibitory effects of glutathione level-raising agents and D-alpha-tocopherol on ornithine decarboxylase induction and mouse skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate.
Topics: Amino Acids; Animals; Cysteine; Enzyme Induction; Female; gamma-Glutamyltransferase; Glutamate-Cysteine Ligase; Glutamates; Glutamic Acid; Glutathione; Glycine; In Vitro Techniques; Mice; Ornithine Decarboxylase; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Vitamin E | 1985 |
The effects of putative amino acid neurotransmitters on somata isolated from neurons of the locust central nervous system.
Topics: Action Potentials; Animals; Aspartic Acid; Cysteine; Female; gamma-Aminobutyric Acid; Ganglia; Glutamates; Glutamic Acid; Grasshoppers; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Membrane Potentials; Neurons; Neurotransmitter Agents; Taurine | 1985 |
L-Homocysteic acid as an alternative cytotoxin for studying glutamate-induced cellular degeneration of Huntington's disease and normal skin fibroblasts.
Topics: Aspartic Acid; Cell Survival; Cells, Cultured; Cysteic Acid; Cysteine; Fibroblasts; Glutamates; Glutamic Acid; Homocysteine; Humans; Huntington Disease; In Vitro Techniques; Isomerism; Kainic Acid; Kinetics; N-Methylaspartate; Neurotransmitter Agents; Skin; Time Factors | 1985 |
Phenotypic properties of a unique rpoA mutation (phs) of Escherichia coli.
Topics: Arabinose; Biological Transport; Carrier Proteins; Cysteine; DNA-Directed RNA Polymerases; Escherichia coli; Genes, Bacterial; Glutamates; Glutamic Acid; Melibiose; Mutation; Phenotype; Potassium; Proline; Sodium; Sodium-Hydrogen Exchangers; Sulfates | 1985 |
Determination of cysteinesulfinate, hypotaurine and taurine in physiological samples by reversed-phase high-performance liquid chromatography.
Topics: Alanine; Aminobutyrates; Animals; Chromatography, High Pressure Liquid; Cysteine; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Liver; Male; Neurotransmitter Agents; o-Phthalaldehyde; Rats; Rats, Inbred Strains; Spectrometry, Fluorescence; Taurine | 1985 |
Exchange of cystine and glutamate across plasma membrane of human fibroblasts.
Topics: Amino Acids; Binding, Competitive; Biological Transport, Active; Cell Membrane; Cysteine; Cystine; Ethylmaleimide; Fibroblasts; Glutamates; Glutamic Acid; Humans | 1986 |
Amino acid neurotransmitters in the CNS. Characteristics of the acidic amino acid exchange.
Topics: Amino Acids; Amino Acids, Sulfur; Animals; Aspartic Acid; Biological Transport; Brain Chemistry; Cysteic Acid; Cysteine; Glutamates; Glutamic Acid; Kinetics; Neurotransmitter Agents; Rats; Stimulation, Chemical; Synaptosomes | 1986 |
Comparison of responses to transmitter candidates at an N-methylaspartate receptor mediated synapse, in slices of rat cerebral cortex.
Topics: Amino Acids; Animals; Aspartic Acid; Cerebral Cortex; Cysteic Acid; Cysteine; Glutamates; Glutamic Acid; Magnesium; Male; N-Methylaspartate; Neurotransmitter Agents; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synaptic Transmission | 1986 |
The binding of acidic amino acids to snail, Helix aspersa, periesophagic ring membranes reveals a single high-affinity glutamate/kainate site.
Topics: Amino Acids; Animals; Aspartic Acid; Binding Sites; Cysteine; Ganglia; Glutamates; Glutamic Acid; Helix, Snails; Hydrogen-Ion Concentration; In Vitro Techniques; Kainic Acid; Kinetics; Neurotransmitter Agents; Osmolar Concentration | 1986 |
Transport of cysteate by synaptosomes isolated from rat brain: evidence that it utilizes the same transporter as aspartate, glutamate, and cysteine sulfinate.
Topics: Amino Acids, Sulfur; Animals; Aspartic Acid; Binding, Competitive; Biological Transport; Brain; Carrier Proteins; Chromatography, High Pressure Liquid; Cysteic Acid; Cysteine; Glutamates; Glutamic Acid; Male; Neurotransmitter Agents; Potassium; Rats; Rats, Inbred Strains; Synaptosomes; Veratridine | 1986 |
Lecithin:cholesterol acyltransferase. Functional regions and a structural model of the enzyme.
Topics: Amino Acid Sequence; Binding Sites; Carboxypeptidases; Cyanogen Bromide; Cysteine; Disulfides; Endopeptidases; Glutamates; Glutamic Acid; Glycosylation; Humans; Peptide Fragments; Phenylalanine; Phosphatidylcholine-Sterol O-Acyltransferase; Protein Conformation; Serine Endopeptidases; Trypsin | 1987 |
Multiple Cl(-)-independent binding sites for the excitatory amino acids: glutamate, aspartate and cysteine sulfinate in rat brain membranes.
Topics: Animals; Aspartic Acid; Brain; Chlorides; Cysteine; Glutamates; Glutamic Acid; Kinetics; Male; Membranes; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Sodium; Synaptic Membranes | 1987 |
Characterization of metal binding peptides from cadmium resistant plant cells.
Topics: Amino Acids; Cadmium; Carrier Proteins; Chromatography, Gel; Cysteine; Glutamates; Glutamic Acid; Glycine; Molecular Weight; Peptides; Plant Proteins; Plants; Protein Denaturation | 1987 |
Cytoprotective effects of glycine and glutathione against hypoxic injury to renal tubules.
Topics: Adenosine Triphosphate; Animals; Cysteine; Dithiothreitol; Female; Glutamates; Glutamic Acid; Glutathione; Glycine; Kidney Diseases; Kidney Tubules, Proximal; Oxygen; Oxygen Consumption; Potassium; Rabbits | 1987 |
Anti-convulsant effects by reduced glutathione and related aminoacids in rats treated with isoniazid.
Topics: Animals; Brain Chemistry; Cysteine; Drug Interactions; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutathione; Glycine; Isoniazid; Lethal Dose 50; Male; Rats; Rats, Inbred Strains; Seizures | 1988 |
Subtle alteration of the active site of ribulose bisphosphate carboxylase/oxygenase by concerted site-directed mutagenesis and chemical modification.
Topics: Amino Acid Sequence; Base Sequence; Carbamates; Catalysis; Cysteine; Glutamates; Glutamic Acid; Mutation; Protein Conformation; Rhodospirillum rubrum; Ribulose-Bisphosphate Carboxylase | 1988 |
Inhibition by forskolin of excitatory amino acid-induced accumulation of cyclic AMP in guinea pig hippocampal slices.
Topics: Adenosine; Amino Acids; Animals; Aspartic Acid; Chlorides; Colforsin; Cyclic AMP; Cysteine; Drug Interactions; Ethylmaleimide; Glutamates; Glutamic Acid; Guanosine Triphosphate; Guinea Pigs; Hippocampus; Histamine; Male; N-Methylaspartate; Neurotransmitter Agents; Veratridine | 1988 |
A novel function of glutamine in cell culture: utilization of glutamine for the uptake of cystine in human fibroblasts.
Topics: Biological Transport, Active; Cells, Cultured; Cysteine; Cystine; Fibroblasts; Glutamates; Glutamic Acid; Glutamine; Humans; Sodium | 1988 |
Glutathione turnover in human erythrocytes. Inhibition by buthionine sulfoximine and incorporation of glycine by exchange.
Topics: Buthionine Sulfoximine; Cysteine; Erythrocytes; Glutamates; Glutamic Acid; Glutathione; Glycine; Humans; Kinetics; Methionine Sulfoximine | 1981 |
Tissue glutathione as a cyst(e)ine reservoir during fasting and refeeding of rats.
Topics: Animals; Cysteine; Cystine; Erythrocytes; Fasting; Food; Glutamates; Glutamic Acid; Glutathione; Glycine; Intestine, Small; Liver; Male; Muscles; Rats | 1981 |
A stereoselective anomaly in dicarboxylic amino acid transport.
Topics: Amino Acids, Sulfur; Animals; Aspartic Acid; Biological Transport; Cells, Cultured; Cysteic Acid; Cysteine; Fibroblasts; Glutamates; Glutamic Acid; Humans; Hydrogen-Ion Concentration; Liver; Neurotransmitter Agents; Rats; Sodium; Stereoisomerism; Sulfinic Acids | 1981 |
Agonist potency determination by patch clamp analysis of single glutamate receptors.
Topics: Animals; Cysteine; Electric Stimulation; Glutamates; Glutamic Acid; Grasshoppers; Ion Channels; Membrane Potentials; Neural Conduction; Neuromuscular Junction; Neurotransmitter Agents; Oxadiazoles; Quisqualic Acid; Receptors, Cell Surface; Receptors, Glutamate; Stimulation, Chemical | 1981 |
Cysteine sulfinic acid in the central nervous system: specific binding of [35S]cysteic acid to cortical synaptic membranes--an investigation of possible binding sites for cysteine sulfinic acid.
Topics: Amino Acids, Sulfur; Animals; Binding Sites; Cerebral Cortex; Cysteic Acid; Cysteine; Glutamates; Glutamic Acid; Male; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Sodium; Substrate Specificity; Synaptic Membranes; Time Factors | 1982 |
Cysteine sulfinic acid in the central nervous system: antagonistic effect of taurine on cysteine sulfinic acid-stimulated formation of cyclic AMP in guinea pig hippocampal slices.
Topics: Animals; Aspartic Acid; Cerebral Cortex; Corpus Striatum; Cyclic AMP; Cysteine; Glutamates; Glutamic Acid; Guinea Pigs; Hippocampus; Male; Neurotransmitter Agents; Taurine | 1982 |
Roles of cysteine sulfinate and transaminase on in vitro dark reversion of urocanase in Pseudomonas putida.
Topics: Alanine; Cysteine; Darkness; Glutamates; Glutamic Acid; Hydro-Lyases; Neurotransmitter Agents; Pseudomonas; Taurine; Transaminases; Ultraviolet Rays; Urocanate Hydratase | 1982 |
Effect of amino acids on microbial production of citric acid by Aspergillus niger.
Topics: Amino Acids; Aspartic Acid; Aspergillus niger; Citrates; Citric Acid; Cysteine; Glutamates; Glutamic Acid; Lysine; Serine | 1982 |
Transport of cystine and cysteine and cell growth in cultured human diploid fibroblasts: effect of glutamate and homocysteate.
Topics: Amino Acids; Biological Transport; Cell Division; Cell Line; Culture Media; Cysteine; Cystine; Fibroblasts; Glutamates; Glutamic Acid; Glutathione; Homocysteine; Humans | 1982 |
Inhibition by Diazepam and γ-Aminobutyric Acid of Depolarization-Induced Release of [¹⁴C]Cysteine Sulfinate and [³H]Glutamate in Rat Hippocampal Slices.
Topics: Animals; Carbon Radioisotopes; Cysteine; Diazepam; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Kinetics; Male; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Tritium | 1983 |
Chronic infusion of endogenous excitatory amino acids into rat striatum and hippocampus.
Topics: Animals; Aspartic Acid; Corpus Striatum; Cysteine; Glutamates; Glutamic Acid; Hippocampus; Male; Neurotransmitter Agents; Rats | 1983 |
Histamine as a ligand in blood plasma. Part 6. Aspartate and glutamate as possible partner ligands for zinc and histamine to favour histamine catabolism.
Topics: Aspartic Acid; Cysteine; Diffusion; Glutamates; Glutamic Acid; Histamine; Humans; Ligands; Zinc | 1982 |
Investigations into the mechanism of excitant amino acid cytotoxicity using a well-characterized glutamatergic system.
Topics: Animals; Aspartic Acid; Concanavalin A; Cysteine; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Grasshoppers; Kainic Acid; Nerve Degeneration; Neuromuscular Junction; Neurotransmitter Agents; Oxadiazoles; Quisqualic Acid; Receptors, Cell Surface; Receptors, Glutamate; Synaptic Transmission | 1983 |
Reduction of the beta-Cys-gamma-Glu thiol ester bond of human C3 with sodium borohydride.
Topics: Borohydrides; Complement C3; Cysteine; Esters; Glutamates; Glutamic Acid; Humans; Oxidation-Reduction; Peptide Fragments; Sulfhydryl Compounds; Trypsin | 1983 |
A comparative study of L[3H]-glutamate and L[3H]-cysteine sulfinate binding sites in subcellular fractions of rat brain.
Topics: Animals; Brain; Cysteine; Freezing; Glutamates; Glutamic Acid; Male; Mitochondria; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, Glutamate; Subcellular Fractions; Synaptic Membranes; Synaptic Transmission; Synaptosomes | 1984 |
Extracellular metabolism of glutathione accounts for its disappearance from the basolateral circulation of the kidney.
Topics: Animals; Carbon Radioisotopes; Cysteine; Glutamates; Glutamic Acid; Glutathione; Glycine; Kidney; Male; Radioisotope Dilution Technique; Rats; Rats, Inbred Strains; Renal Circulation; Sulfur Radioisotopes | 1984 |
Modulation by bovine serum albumin of stimulated formation of cyclic AMP in guinea pig hippocampus.
Topics: Adenylyl Cyclases; Animals; Aspartic Acid; Cyclic AMP; Cysteine; Glutamates; Glutamic Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Male; Neurotransmitter Agents; Serum Albumin, Bovine | 1984 |
Thiazolidine-2-carboxylate derivatives formed from glyoxylate and L-cysteine or L-cysteinylglycine as possible physiological substrates for D-aspartate oxidase.
Topics: Amino Acid Oxidoreductases; Animals; Aspartic Acid; Cattle; Cysteine; D-Aspartate Oxidase; Dipeptides; Glutamates; Glutamic Acid; Glyoxylates; Hydrogen-Ion Concentration; Proline; Substrate Specificity; Thiazolidines | 1984 |
Decreased cysteine and proline synthesis in parenterally fed, premature infants.
Topics: Alanine; Amino Acids; Aspartic Acid; Birth Weight; Blood Glucose; Carbon Isotopes; Cysteine; Electrolytes; Energy Intake; Female; Food, Formulated; Gas Chromatography-Mass Spectrometry; Gestational Age; Glucose; Glutamic Acid; Glycine; Humans; Infant Food; Infant Nutritional Physiological Phenomena; Infant, Newborn; Infant, Premature; Lipids; Male; Parenteral Nutrition; Parenteral Nutrition Solutions; Proline; Serine; Solutions | 1995 |
Cloning of the cDNA for a brain glycine-, glutamate- and thienylcyclohexylpiperidine-binding protein.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Blotting, Northern; Brain; Cloning, Molecular; Cysteine; DNA, Complementary; Gene Library; Glutamic Acid; Glycine; Hippocampus; Illicit Drugs; Kinetics; Membrane Glycoproteins; Molecular Sequence Data; Nerve Tissue Proteins; Phencyclidine; Rats; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Sequence Homology, Amino Acid; Substrate Specificity; Synaptic Membranes | 1995 |
Clustering and co-transcription of the Bacillus subtilis genes encoding the aminoacyl-tRNA synthetases specific for glutamate and for cysteine and the first enzyme for cysteine biosynthesis.
Topics: Amino Acid Sequence; Amino Acyl-tRNA Synthetases; Bacillus subtilis; Base Sequence; Cloning, Molecular; Cysteine; DNA, Bacterial; Escherichia coli; Geobacillus stearothermophilus; Glutamates; Glutamic Acid; Molecular Sequence Data; Multigene Family; Nucleic Acid Conformation; RNA, Bacterial; Sequence Homology, Amino Acid; Substrate Specificity; Transcription, Genetic | 1994 |
NMDA receptor channels: subunit-specific potentiation by reducing agents.
Topics: Alanine; Animals; Base Sequence; Cell Line; Cloning, Molecular; Cysteine; Dithiothreitol; Drug Synergism; Ethylmaleimide; Glutamates; Glutamic Acid; Glutathione; Humans; Ion Channels; Kidney; Kinetics; Macromolecular Substances; Membrane Potentials; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Rats; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins; Serine; Transfection | 1994 |
Characterization of nitric oxide generator-induced hippocampal [3H]norepinephrine release. I. The role of glutamate.
Topics: Animals; Calcium; Cyclic GMP; Cysteine; Cytoplasm; Glutamic Acid; Hippocampus; Hydroxylamine; Hydroxylamines; In Vitro Techniques; Male; Nitric Oxide; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; S-Nitrosothiols; Stimulation, Chemical; Tritium; Vasodilator Agents | 1995 |
Discriminative stimulus effects of excitatory amino acid agonists in rats.
Topics: Animals; Conditioning, Operant; Cysteine; Discrimination, Psychological; Dose-Response Relationship, Drug; Excitatory Amino Acids; Glutamic Acid; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley | 1995 |
Purification and characterization of a low molecular weight endogenous glutamate binding inhibitor (LGBI) in porcine brain.
Topics: Amino Acids; Animals; Biological Factors; Brain; Cysteine; Drug Stability; Excitatory Amino Acid Antagonists; Glutamic Acid; Glutamine; Membranes; Molecular Weight; Receptors, Glutamate; Swine | 1995 |
Changes in levels of glutathione and related compounds and activities of glutathione-related enzymes during rat liver regeneration.
Topics: Animals; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Cysteine; Glutamate-Cysteine Ligase; Glutamic Acid; Glutathione; Glutathione Disulfide; Glycine; Hepatectomy; Liver; Liver Regeneration; Male; Rats; Rats, Wistar | 1995 |
Uptake and receptor sites for glycine in isolated bovine adrenal medulla chromaffin cells.
Topics: Acetamides; Adrenal Medulla; Alanine; Animals; beta-Alanine; Cattle; Cell Membrane; Choline; Cysteine; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Kinetics; Ouabain; Receptors, Glycine; Sarcosine; Sodium; Strychnine; Taurine; Temperature | 1993 |
Replacing the glutamate ligand in the structural zinc site of Sulfolobus solfataricus alcohol dehydrogenase with a cysteine decreases thermostability.
Topics: Alcohol Dehydrogenase; Base Sequence; Binding Sites; Cloning, Molecular; Cysteine; Enzyme Stability; Glutamic Acid; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Molecular Structure; Point Mutation; Protein Engineering; Recombinant Proteins; Sequence Alignment; Sulfolobus; Temperature; Zinc | 1995 |
Increased levels of oxidized glutathione in CD4+ lymphocytes associated with disturbed intracellular redox balance in human immunodeficiency virus type 1 infection.
Topics: CD4-Positive T-Lymphocytes; Cysteine; Glutamic Acid; Glutamine; Glutathione; HIV Infections; HIV-1; Humans; Interleukin-2; Lymphocyte Subsets; Oxidation-Reduction; Oxidative Stress; Tumor Necrosis Factor-alpha | 1995 |
Hazards of antioxidant combinations containing superoxide dismutase.
Topics: Aerobiosis; Animals; Antioxidants; Cell Hypoxia; Cells, Cultured; Copper; Cysteine; Drug Interactions; Epithelium; Glutamic Acid; Glutathione; Glutathione Disulfide; Glycine; Kidney Tubules, Proximal; Lipid Peroxidation; Lipid Peroxides; Male; Rats; Rats, Sprague-Dawley; Reperfusion; Superoxide Dismutase | 1995 |
Effect of reactive oxygen intermediates and antioxidants on proliferation and function of T lymphocytes.
Topics: Amino Acids; Antioxidants; Biological Transport; Cell Line; Cysteine; Cystine; DNA Replication; Glutamic Acid; Glutathione; Glutathione Disulfide; Humans; Hydrogen Peroxide; Kinetics; Lymphocyte Activation; Reactive Oxygen Species; T-Lymphocyte Subsets; T-Lymphocytes | 1994 |
Cystine uptake and glutathione level in fetal brain cells in primary culture and in suspension.
Topics: Animals; beta-Alanine; Biological Transport; Brain; Cells, Cultured; Cysteine; Cystine; Female; Fetus; Glutamates; Glutamic Acid; Glutathione; In Vitro Techniques; Kinetics; Neurons; Pregnancy; Rats; Rats, Wistar; Serine; Sodium; Time Factors | 1993 |
Plasma amino acid dysregulation after lentiviral infection.
Topics: Amino Acids; Animals; Arthritis-Encephalitis Virus, Caprine; Chlorocebus aethiops; Cysteine; Cystine; Glutamates; Glutamic Acid; Goat Diseases; Goats; Hepatitis B; HIV Infections; HIV-1; Humans; Lentivirus Infections; Macaca mulatta; Pan troglodytes; Proline; Simian Acquired Immunodeficiency Syndrome | 1993 |
Glycine-glutamate interactions at the NMDA receptor: role of cysteine residues.
Topics: Animals; Cysteine; Disulfides; Glutamates; Glutamic Acid; Glycine; Mutagenesis, Site-Directed; Receptors, N-Methyl-D-Aspartate; Xenopus laevis | 1993 |
Brain amino acid levels are related to seizure propensity in the gerbil (Meriones unguiculatus).
Topics: Amino Acids; Analysis of Variance; Animals; Arginine; Aspartic Acid; Behavior, Animal; Brain; Citrulline; Cysteine; Disease Susceptibility; Female; Gerbillinae; Glucose; Glutamates; Glutamic Acid; Glutamine; Glycine; Male; Seizures | 1993 |
Identification of Cys139 and Glu207 as catalytically important groups in the active site of isopentenyl diphosphate:dimethylallyl diphosphate isomerase.
Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Carbon-Carbon Double Bond Isomerases; Catalysis; Cysteine; DNA Primers; Glutamates; Glutamic Acid; Hemiterpenes; Isomerases; Molecular Sequence Data; Mutagenesis, Site-Directed | 1994 |
Secretion of alpha 2-plasmin inhibitor is impaired by amino acid deletion in a small region of the molecule.
Topics: alpha-2-Antiplasmin; Amino Acid Sequence; Animals; Cell Line; Cysteine; DNA, Complementary; Enzyme-Linked Immunosorbent Assay; Glutamates; Glutamic Acid; Haplorhini; Molecular Sequence Data; Mutagenesis, Site-Directed; Transfection | 1994 |
Oxidant-antioxidant status in human immunodeficiency virus infection.
Topics: Amino Acids; Antioxidants; Biomarkers; Cell Separation; Cells, Cultured; Culture Techniques; Cysteine; Cystine; Female; Glutamates; Glutamic Acid; Glutathione; HIV Infections; HIV Seropositivity; Humans; Indicators and Reagents; Lymphocytes; Male; Monocytes; Oxidants; Reference Values; Sex Characteristics; Spectrophotometry | 1994 |
Non-reciprocal cross-adaptation of spiking responses of individual olfactory receptor neurons of spiny lobsters: evidence for two excitatory transduction pathways.
Topics: Acclimatization; Adenosine Monophosphate; Ammonium Chloride; Animals; Betaine; Cysteine; Glutamates; Glutamic Acid; In Vitro Techniques; Nephropidae; Odorants; Olfactory Receptor Neurons; Signal Transduction; Succinates; Taurine | 1994 |
L-glutamate uptake inhibitors may stimulate phosphoinositide hydrolysis in baby hamster kidney cells expressing mGluR1a via heteroexchange with L-glutamate without direct activation of mGluR1a.
Topics: Alanine Transaminase; Animals; Asparagine; Aspartic Acid; Cell Line; Cell Membrane; Cricetinae; Cycloleucine; Cysteine; Dicarboxylic Acids; Excitatory Amino Acid Antagonists; Glutamate Decarboxylase; Glutamic Acid; Hydrolysis; Kidney; N-Methylaspartate; Phosphatidylinositols; Pyrrolidines; Receptors, Metabotropic Glutamate | 1994 |
Inhibitory effects of nitric oxide on the uptake of [3H]dopamine and [3H]glutamate by striatal synaptosomes.
Topics: Animals; Catalase; Cattle; Corpus Striatum; Cysteine; Dopamine; Glutamic Acid; Hemoglobins; Male; Nitric Oxide; Nitroprusside; Nomifensine; Rats; Rats, Sprague-Dawley; S-Nitrosothiols; Superoxide Dismutase; Synaptosomes; Temperature; Tritium | 1994 |
The cooperative binding of chromosomal protein HMG-14 to nucleosome cores is reduced by single point mutations in the nucleosomal binding domain.
Topics: Alanine; Base Sequence; Binding Sites; Cysteine; Escherichia coli; Gene Expression; Glutamic Acid; High Mobility Group Proteins; Humans; Iodoacetamide; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Nucleosomes; Point Mutation; Protein Conformation; Recombinant Proteins; Structure-Activity Relationship; Sulfhydryl Compounds | 1994 |
Culture of a differentiated liver cell line, Hep G2, in serum with application to a bioartificial liver: effect of supplementation of serum with amino acids.
Topics: Amino Acids; Artificial Organs; Blood; Carcinoma, Hepatocellular; Cell Differentiation; Cell Division; Cell Survival; Culture Media; Cysteine; Glutamic Acid; Glutathione; Glycine; Humans; Liver; Liver Neoplasms; Tumor Cells, Cultured | 1994 |
Transamination and transsulphuration of L-cysteine in Ehrlich ascites tumor cells and mouse liver. The nonenzymatic reaction of L-cysteine with pyruvate.
Topics: Amines; Animals; Biotransformation; Carcinoma, Ehrlich Tumor; Cystathionine gamma-Lyase; Cysteine; Glutamates; Glutamic Acid; Liver; Mice; Sulfur; Sulfurtransferases; Thiocyanates; Thiosulfate Sulfurtransferase; Transaminases | 1993 |
Autoradiography of L-[3H]aspartate binding sites.
Topics: Amino Acid Transport Systems; Animals; Aspartic Acid; Autoradiography; Binding Sites; Brain; Buffers; Carrier Proteins; Cysteic Acid; Cysteine; Glutamates; Glutamic Acid; Kinetics; Male; Neurotransmitter Agents; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid; Sodium; Stereoisomerism; Tritium | 1993 |
Glutamate uptake system in the presynaptic vesicle: glutamic acid analogs as inhibitors and alternate substrates.
Topics: Animals; Cattle; Cerebral Cortex; Cycloleucine; Cysteine; Glutamates; Glutamic Acid; Synaptic Vesicles; Tryptophan | 1993 |
Substitution mutations at the putative catalytic triad of the poliovirus 3C protease have differential effects on cleavage at different sites.
Topics: 3C Viral Proteases; Binding Sites; Cell-Free System; Cysteine; Cysteine Endopeptidases; Glutamates; Glutamic Acid; Point Mutation; Poliovirus; Protein Biosynthesis; Protein Processing, Post-Translational; Structure-Activity Relationship; Transfection; Viral Proteins; Virus Replication | 1993 |
The plasma amino acid response to cafeteria feeding and essential-amino acid gavage in weaning rats.
Topics: Alanine; Amino Acids; Amino Acids, Essential; Animals; Cysteine; Diet; Female; Food Services; Glutamates; Glutamic Acid; Glutamine; Glycine; Hydroxyproline; Methionine; Ornithine; Proline; Rats; Rats, Wistar | 1993 |
Aldehyde dehydrogenase: aldehyde dehydrogenation and ester hydrolysis.
Topics: Aldehyde Dehydrogenase; Aldehydes; Binding Sites; Cinnamates; Cysteine; Esters; Glutamates; Glutamic Acid; Humans; Hydrolysis; Imidazoles; In Vitro Techniques; Iodoacetamide; Isoenzymes; Kinetics; Liver; Substrate Specificity | 1993 |
Determination of the pKa values of active-center cysteines, cysteines-32 and -35, in Escherichia coli thioredoxin by Raman spectroscopy.
Topics: Amino Acid Sequence; Aspartic Acid; Chemical Phenomena; Chemistry, Physical; Cysteine; Escherichia coli; Glutamates; Glutamic Acid; Hydrogen Bonding; Hydrogen-Ion Concentration; Molecular Sequence Data; Protein Conformation; Protein Structure, Secondary; Solutions; Spectrum Analysis, Raman; Thioredoxins; Tryptophan; Tyrosine | 1993 |
Cellular oxidation of low density lipoprotein is caused by thiol production in media containing transition metal ions.
Topics: Animals; Cell Line; Cells, Cultured; Culture Media; Cysteine; Cystine; Endothelium, Vascular; Glutamates; Glutamic Acid; Lipoproteins, LDL; Macrophages; Maleates; Metals; Oxidation-Reduction; Sulfhydryl Compounds | 1993 |
Functional analysis of conserved residues in the active site of insulin-degrading enzyme.
Topics: Amino Acid Sequence; Animals; Binding Sites; Catalysis; Cells, Cultured; Conserved Sequence; Cysteine; Glutamates; Glutamic Acid; Haplorhini; Humans; Hydrolysis; Insulysin; Mutagenesis, Site-Directed; Substrate Specificity | 1993 |
D38 is an essential part of the proton translocation pathway in bacteriorhodopsin.
Topics: Amino Acid Sequence; Aspartic Acid; Bacteriorhodopsins; Cysteine; Glutamic Acid; Halobacterium; Hydrogen-Ion Concentration; Kinetics; Light; Models, Structural; Mutagenesis, Site-Directed; Point Mutation; Protein Structure, Secondary; Recombinant Proteins; Spectrophotometry; Spectroscopy, Fourier Transform Infrared | 1996 |
Studies on identifying the catalytic role of Glu-204 in the active site of yeast invertase.
Topics: Amino Acid Sequence; Bacteria; Base Sequence; beta-Fructofuranosidase; Binding Sites; Catalysis; Cysteine; Dithiothreitol; Glutamic Acid; Glycoside Hydrolases; Histidine; Hydrogen-Ion Concentration; Iodine; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Plants; Point Mutation; Recombinant Proteins; Saccharomyces cerevisiae; Sequence Homology, Amino Acid | 1996 |
Differentiation of catalytic sites on Escherichia coli F1ATPase by laser photoactivated labeling with [3H]-2-Azido-ATP using the mutant beta Glu381Cys:epsilonSer108Cys to identify different beta subunits by their interactions with gamma and epsilon subuni
Topics: Adenosine Triphosphate; Affinity Labels; Azides; Cysteine; Edetic Acid; Escherichia coli; Glutamic Acid; Kinetics; Macromolecular Substances; Magnesium; Mutagenesis, Site-Directed; Photolysis; Point Mutation; Protein Binding; Proton-Translocating ATPases; Recombinant Proteins; Serine; Spectrometry, Fluorescence; Tritium | 1996 |
The central effect of L-cysteine on cardiovascular system of the conscious rat.
Topics: Animals; Blood Pressure; Cardiovascular Physiological Phenomena; Cardiovascular System; Cysteine; Glutamic Acid; Heart Rate; Injections, Spinal; Male; Rats; Rats, Wistar; Time Factors | 1995 |
Woodward's reagent K inactivation of Escherichia coli L-threonine dehydrogenase: increased absorbance at 340-350 nm is due to modification of cysteine and histidine residues, not aspartate or glutamate carboxyl groups.
Topics: Alcohol Oxidoreductases; Amino Acid Sequence; Aspartic Acid; Bacterial Proteins; Cysteine; Enzyme Inhibitors; Escherichia coli; Glutamic Acid; Histidine; Isoxazoles; Kinetics; Models, Chemical; Molecular Sequence Data; Solvents; Spectrophotometry, Ultraviolet; Sulfhydryl Compounds | 1996 |
Effects of both shortening and lengthening the active site nucleophile of Bacillus circulans xylanase on catalytic activity.
Topics: Amino Acid Sequence; Aspartic Acid; Bacillus; Base Sequence; Binding Sites; Carbohydrate Conformation; Carbohydrate Sequence; Catalysis; Cysteine; Glutamic Acid; Glycoside Hydrolases; Glycosylation; Iodoacetates; Iodoacetic Acid; Kinetics; Mass Spectrometry; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Point Mutation; Xylan Endo-1,3-beta-Xylosidase; Xylosidases | 1996 |
Development of brain damage after neonatal hypoxia-ischemia: excitatory amino acids and cysteine.
Topics: Animals; Brain Diseases; Brain Ischemia; Cysteine; Excitatory Amino Acids; Glutamic Acid; Rats; Time Factors | 1996 |
Interaction of L-cysteine with a human excitatory amino acid transporter.
Topics: Alanine; Amino Acid Transport System X-AG; Animals; Binding, Competitive; Biological Transport, Active; Brain Chemistry; Carrier Proteins; Cysteine; Electrophysiology; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Humans; Kinetics; Oocytes; Patch-Clamp Techniques; Protons; Receptors, Neurotransmitter; Symporters; Xenopus laevis | 1996 |
Structural and functional analysis of the spontaneous re-formation of the thiol ester bond in human alpha 2-macroglobulin, rat alpha 1-inhibitor-3 and chemically modified derivatives.
Topics: Acute-Phase Proteins; alpha-Macroglobulins; Animals; Cysteine; Esters; Glutamic Acid; Humans; Kinetics; Macromolecular Substances; Protease Inhibitors; Rats; Sulfhydryl Compounds; Trypsin | 1996 |
Genetic and biochemical characterization of mutations in the ATPase and helicase regions of the Upf1 protein.
Topics: Adenosine Triphosphatases; Alanine; Amino Acid Sequence; Base Sequence; Binding Sites; Chromatography, Ion Exchange; Cloning, Molecular; Conserved Sequence; Cysteine; DNA Helicases; DNA Probes; Escherichia coli; Fungal Proteins; Glutamic Acid; Histidine; Kinetics; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Recombinant Proteins; RNA Helicases; RNA, Messenger; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Trans-Activators | 1996 |
Neurotoxicity of cysteine: interaction with glutamate.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Cells, Cultured; Cerebral Cortex; Cysteine; Dizocilpine Maleate; Ethanolamines; Glutamic Acid; Microdialysis; Neurons; Neuroprotective Agents; Neurotoxins; Rats; Rats, Sprague-Dawley; Taurine | 1995 |
Gamma-glutamyl peptides and related amino acids in rat hippocampus in vitro: effect of depolarization and gamma-glutamyl transpeptidase inhibition.
Topics: Amino Acids; Animals; Aspartic Acid; Cysteine; Dipeptides; Enzyme Inhibitors; Female; gamma-Glutamyltransferase; Glutamates; Glutamic Acid; Glutamine; Glutathione; Hippocampus; Isoxazoles; Male; Rats; Rats, Sprague-Dawley | 1996 |
Apoptosis induced by beta-N-oxalylamino-L-alanine on a motoneuron hybrid cell line.
Topics: Amino Acids, Diamino; Animals; Apoptosis; beta-Alanine; Cell Count; Cysteine; Dose-Response Relationship, Drug; Glutamic Acid; Motor Neurons; Rats; Time Factors; Tumor Cells, Cultured | 1996 |
Role of Na(+)-Ca2+ exchanger in agonist-induced Ca2+ signaling in cultured rat astrocytes.
Topics: Adenosine Triphosphate; Amiloride; Animals; Animals, Newborn; Astrocytes; Base Sequence; Bucladesine; Calcium; Carrier Proteins; Cells, Cultured; Cerebral Cortex; Cyclic GMP; Cysteine; Glutamic Acid; Ionomycin; Kinetics; Nitric Oxide; Nitroprusside; Norepinephrine; Oligonucleotides, Antisense; Phosphatidylinositols; Rats; Rats, Sprague-Dawley; S-Nitrosothiols; Signal Transduction; Sodium-Calcium Exchanger | 1996 |
Ligand-binding characteristics and related structural features of the expressed goldfish kainate receptors: identification of a conserved disulfide bond and three residues important for ligand binding.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cells, Cultured; Cerebellum; Cloning, Molecular; Cysteine; Disulfides; Dithiothreitol; DNA Mutational Analysis; Glutamic Acid; Goldfish; Humans; Kainic Acid; Kidney; Kinetics; Ligands; Membranes; Molecular Sequence Data; Receptors, Kainic Acid; Transfection; Tritium | 1996 |
Different preferences in the utilization of amino acids for glutathione synthesis in cultured neurons and astroglial cells derived from rat brain.
Topics: Amino Acids; Animals; Astrocytes; Brain; Cells, Cultured; Cysteine; Cystine; Glutamic Acid; Glutamine; Glutathione; Neurons; Rats; Rats, Wistar | 1996 |
Effects of the intramolecular disulfide bond on ligand binding dynamics in myoglobin.
Topics: Binding Sites; Cysteine; Disulfides; Glutamic Acid; Humans; Isoleucine; Kinetics; Ligands; Magnetic Resonance Spectroscopy; Models, Chemical; Mutagenesis, Site-Directed; Myoglobin; Protein Conformation; Recombinant Proteins; Spectrophotometry, Infrared; Thermodynamics | 1997 |
Bicarbonate-sensitive cysteine induced elevation of extracellular aspartate and glutamate in rat hippocampus in vitro.
Topics: Animals; Aspartic Acid; Bicarbonates; Cysteine; Cystine; Extracellular Space; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; In Vitro Techniques; Neurotransmitter Agents; Rats; Taurine | 1997 |
Dominant negative mutant of ionotropic glutamate receptor subunit GluR3: implications for the role of a cysteine residue for its channel activity and pharmacological properties.
Topics: Amino Acid Sequence; Animals; Cell Compartmentation; Cell Membrane; Cysteine; Dose-Response Relationship, Drug; Electrophysiology; Glutamic Acid; Ion Channels; Kainic Acid; Molecular Sequence Data; Oocytes; Phenotype; Point Mutation; Protein Conformation; Receptors, AMPA; Recombinant Proteins; Structure-Activity Relationship; Xenopus | 1997 |
Brain injury after hypoxia-ischemia in newborn rats: relationship to extracellular levels of excitatory amino acids and cysteine.
Topics: Analysis of Variance; Animals; Animals, Newborn; Aspartic Acid; Brain; Brain Injuries; Carotid Artery, Common; Cysteine; Excitatory Amino Acids; Extracellular Space; Factor Analysis, Statistical; Female; Glutamic Acid; Hypoxia, Brain; Ischemic Attack, Transient; Male; Microdialysis; Rats; Rats, Wistar; Reperfusion; Statistics, Nonparametric | 1997 |
The glutathione level of retinal Müller glial cells is dependent on the high-affinity sodium-dependent uptake of glutamate.
Topics: 2-Aminoadipic Acid; Amino Acid Transport System X-AG; Animals; Carrier Proteins; Chromatography, High Pressure Liquid; Cysteine; Dicarboxylic Acids; Electrophysiology; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Glutathione; Guinea Pigs; Image Processing, Computer-Assisted; Neuroglia; Oxidation-Reduction; Pyrrolidines; Retina; Sodium; Symporters; Time Factors | 1997 |
Contributing mechanisms for cysteine excitotoxicity in cultured cerebellar granule cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Bicarbonates; Biological Transport; Cell Death; Cells, Cultured; Cerebellum; Culture Media; Cysteine; Dithiothreitol; Dizocilpine Maleate; Glutamic Acid; Hydrogen-Ion Concentration; Kinetics; Magnesium; Neurons; Neurotoxins; Rats; Rats, Wistar | 1996 |
Ether extract of fetal calf serum protects cultured rat cortical neurons against glutamate cytotoxicity.
Topics: Animals; Cattle; Cells, Cultured; Cerebral Cortex; Corpus Striatum; Cysteine; Dose-Response Relationship, Drug; Ethers; Fetal Blood; Glutamic Acid; Neurons; Nitric Oxide; Rats; S-Nitrosothiols | 1997 |
Association of c-fos mRNA expression and excitotoxicity in primary cultures of mouse neocortical and cerebellar neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Death; Cells, Cultured; Cerebellar Cortex; Cerebral Cortex; Cysteine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Genes, fos; Glutamic Acid; Kainic Acid; Mice; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Proto-Oncogene Proteins c-fos; RNA, Messenger | 1997 |
Use of dipeptides for the synthesis of glutathione by astroglia-rich primary cultures.
Topics: Animals; Astrocytes; Buthionine Sulfoximine; Cells, Cultured; Culture Media; Cysteine; Dipeptides; Enzyme Inhibitors; Glucose; Glutamate-Cysteine Ligase; Glutamic Acid; Glutathione; Glycine; Rats; Rats, Wistar | 1997 |
Effect of cysteinesulfinate on fatty acid-dependent uncoupling: modulation of recoupling by substrates of the aspartate/glutamate antiporter and diethyl pyrocarbonate.
Topics: Animals; Aspartic Acid; Atractyloside; Cysteine; Diethyl Pyrocarbonate; Fatty Acids; Glutamic Acid; Mitochondria, Liver; Neurotransmitter Agents; Rats | 1997 |
Glutamate-194 to cysteine mutation inhibits fast light-induced proton release in bacteriorhodopsin.
Topics: Bacteriorhodopsins; Cysteine; Dark Adaptation; Glutamic Acid; Halobacterium; Hydrogen-Ion Concentration; Kinetics; Light; Mutation; Protons; Spectrophotometry, Atomic | 1997 |
Nicotine protects cultured cortical neurons against glutamate-induced cytotoxicity via alpha7-neuronal receptors and neuronal CNS receptors.
Topics: Aconitine; Animals; Bungarotoxins; Cell Survival; Cells, Cultured; Cerebral Cortex; Cysteine; Dihydro-beta-Erythroidine; Excitatory Amino Acid Antagonists; Glutamic Acid; Ionomycin; Ionophores; Neurons; Neuroprotective Agents; Nicotine; Nicotinic Antagonists; Rats; Receptors, Nicotinic; S-Nitrosothiols; Toxins, Biological | 1997 |
Cysteine-scanning mutagenesis of helix IV and the adjoining loops in the lactose permease of Escherichia coli: Glu126 and Arg144 are essential. off.
Topics: Amino Acid Sequence; Amino Acid Substitution; Arginine; Biological Transport; Biological Transport, Active; Cysteine; Escherichia coli; Escherichia coli Proteins; Glutamic Acid; Kinetics; Lactose; Membrane Transport Proteins; Models, Molecular; Molecular Sequence Data; Monosaccharide Transport Proteins; Mutagenesis, Site-Directed; Protein Structure, Secondary; Recombinant Proteins; Symporters | 1997 |
Two novel types of L-glutamate receptors with affinities for NMDA and L-cysteine in the olfactory organ of the Caribbean spiny lobster Panulirus argus.
Topics: Animals; Chemoreceptor Cells; Cysteine; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Space; Glutamic Acid; Kinetics; Nephropidae; Odorants; Radioligand Assay; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Smell; Stimulation, Chemical | 1997 |
Replacement of the active site tyrosine of vaccinia DNA topoisomerase by glutamate, cysteine or histidine converts the enzyme into a site-specific endonuclease.
Topics: Binding Sites; Cysteine; DNA; DNA Topoisomerases, Type I; DNA, Superhelical; Endonucleases; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Mutagenesis; Structure-Activity Relationship; Tyrosine; Vaccinia virus | 1998 |
In vivo localization of diglycylcysteine-bearing synthetic peptides by nuclear imaging of oxotechnetate transchelation.
Topics: Animals; Binding Sites; Chelating Agents; Cysteine; Female; Glutamic Acid; Peptides; Protein Binding; Rats; Rats, Inbred F344; Technetium | 1997 |
Native conformations of human complement components C3 and C4 show different dependencies on thioester formation.
Topics: Amino Acid Substitution; Animals; Chromatography, High Pressure Liquid; Complement C3; Complement C4; Cysteine; Esters; Gene Expression; Glutamic Acid; Humans; Mice; Mutagenesis, Site-Directed; Plasmacytoma; Protein Conformation; Sulfhydryl Compounds; Transfection; Tumor Cells, Cultured | 1998 |
Restoration of catalytic activity beyond wild-type level in glucoamylase from Aspergillus awamori by oxidation of the Glu400-->Cys catalytic-base mutant to cysteinesulfinic acid.
Topics: Alkylation; Amino Acid Substitution; Aspergillus; Carboxylic Acids; Catalysis; Cysteine; Enzyme Activation; Enzyme Stability; Glucan 1,4-alpha-Glucosidase; Glutamic Acid; Isoelectric Focusing; Mutation; Neurotransmitter Agents; Oxidation-Reduction | 1998 |
Enzymatic properties of the cysteinesulfinic acid derivative of the catalytic-base mutant Glu400-->Cys of glucoamylase from Aspergillus awamori.
Topics: 1-Deoxynojirimycin; Acarbose; Amino Acid Substitution; Amino Sugars; Aspergillus; Binding, Competitive; Catalysis; Cysteine; Enzyme Activation; Glucan 1,4-alpha-Glucosidase; Glucose; Glutamic Acid; Hydro-Lyases; Hydrogen-Ion Concentration; Hydrolysis; Isomaltose; Kinetics; Magnetic Resonance Spectroscopy; Mutation; Neurotransmitter Agents; Oligosaccharides; Polysaccharides; Trisaccharides | 1998 |
Mode of action of site-directed irreversible folate analogue inhibitors of thymidylate synthase.
Topics: Amino Acid Sequence; Binding Sites; Cysteine; Enzyme Inhibitors; Escherichia coli; Folic Acid; Glutamic Acid; Kinetics; Molecular Sequence Data; Pyrimidines; Quinazolines; Thymidylate Synthase | 1998 |
Plasma levels of neuroexcitatory amino acids in patients with migraine or tension headache.
Topics: Adult; Aged; Cysteine; Cystine; Excitatory Amino Acids; Female; Glutamic Acid; Humans; Male; Middle Aged; Migraine Disorders; Reactive Oxygen Species; Tension-Type Headache | 1998 |
Hemodynamic effects of L-glutamate in NTS of conscious rats: a possible role of vascular nitrosyl factors.
Topics: Animals; Blood Vessels; Cysteine; Glutamic Acid; Hemodynamics; Hindlimb; Male; Microinjections; Nitroprusside; Nitroso Compounds; Rats; Rats, Sprague-Dawley; S-Nitrosothiols; Solitary Nucleus; Vasodilation | 1998 |
Phosphorylation changes the spatial relationship between Glu124-Arg143 and Cys18 and Cys165 of the regulatory light chain in smooth muscle myosin.
Topics: Amino Acid Sequence; Animals; Arginine; Chickens; Cross-Linking Reagents; Cysteine; Gizzard, Avian; Glutamic Acid; Models, Molecular; Molecular Sequence Data; Mollusca; Muscle, Smooth; Mutagenesis, Site-Directed; Myosin Light Chains; Phosphorylation; Photochemistry | 1998 |
Sulfhydryl oxidation of mutants with cysteine in place of acidic residues in the lactose permease.
Topics: Amino Acid Substitution; Aspartic Acid; Cysteine; Escherichia coli; Escherichia coli Proteins; Glutamic Acid; Membrane Transport Proteins; Monosaccharide Transport Proteins; Mutagenesis, Site-Directed; Oxidation-Reduction; Structure-Activity Relationship; Sulfhydryl Compounds; Sulfinic Acids; Sulfonic Acids; Symporters | 1998 |
Catalytic thiol and carboxylate: role of cysteine and glutamic acid in the xylosidic activity of endoxylanase from Chainia sp. (NCL 82-5-1).
Topics: Amino Acid Sequence; Amino Acids; Binding Sites; Carboxylic Acids; Catalysis; Cysteine; Endo-1,4-beta Xylanases; Enzyme Activation; Glutamic Acid; Molecular Sequence Data; Peptides; Streptomycetaceae; Sulfhydryl Compounds; Xylose; Xylosidases | 1998 |
Sulphur-containing amino acids are agonists for group 1 metabotropic receptors expressed in clonal RGT cell lines.
Topics: Amino Acids, Sulfur; Animals; Cell Line; Cricetinae; Cysteic Acid; Cysteine; Glutamic Acid; Homocysteine; Humans; Mesocricetus; Neurotransmitter Agents; Phosphatidylinositols; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Serine | 1998 |
Topology of the region surrounding Glu681 of human AE1 protein, the erythrocyte anion exchanger.
Topics: Amino Acid Sequence; Amino Acid Substitution; Anion Exchange Protein 1, Erythrocyte; Cell Membrane; Cysteine; Glutamic Acid; Humans; Molecular Sequence Data; Protein Conformation; Water | 1998 |
Subcellular compartmentation of glutathione and glutathione precursors. A high resolution immunogold analysis of the outer retina of guinea pig.
Topics: Animals; Cysteine; Dipeptides; Glutamic Acid; Glutathione; Glycine; Guinea Pigs; Immunohistochemistry; Microscopy, Immunoelectron; Retina | 1998 |
Hepatic export of glutathione and uptake of constituent amino acids, glutamate and cysteine, in broilers in vivo.
Topics: Animals; Biological Transport; Carotid Arteries; Chickens; Cysteine; Cystine; Dipeptides; Enzyme Inhibitors; gamma-Glutamyltransferase; Glutamic Acid; Glutathione; Hepatic Veins; Isoxazoles; Liver; Male; Portal Vein | 1998 |
Glutathione restoration as indicator for cellular metabolism of astroglial cells.
Topics: Amino Acids; Animals; Astrocytes; Cells, Cultured; Cysteine; Glucose; Glutamic Acid; Glutathione; Glycine; Rats; Rats, Wistar; Time Factors | 1998 |
m-Calpain subunits remain associated in the presence of calcium.
Topics: Alanine; Animals; Calcium; Calpain; Caseins; Catalytic Domain; Cattle; Cysteine; Dimerization; Glutamic Acid; Kinetics; Macromolecular Substances; Mutagenesis, Site-Directed; Protein Binding; Recombinant Proteins; Serine | 1998 |
Mutations in the 1A rod domain segment of the keratin 9 gene in epidermolytic palmoplantar keratoderma.
Topics: Arginine; Base Sequence; Child, Preschool; Conserved Sequence; Cysteine; Epidermolysis Bullosa Simplex; Female; Genes, Dominant; Genes, Recessive; Glutamic Acid; Humans; Keratins; Keratoderma, Palmoplantar; Korea; Male; Microscopy, Electron; Pedigree; Point Mutation; Polymerase Chain Reaction; Sequence Analysis, DNA; Tryptophan | 1998 |
Alternative splicing results in differential expression, activity, and localization of the two forms of arginyl-tRNA-protein transferase, a component of the N-end rule pathway.
Topics: Alternative Splicing; Amino Acid Sequence; Aminoacyltransferases; Animals; Arabidopsis; Aspartic Acid; Base Sequence; beta-Galactosidase; Cell Line, Transformed; Cell Nucleus; Cysteine; Cytosol; DNA, Complementary; Drosophila melanogaster; Exons; Gene Expression Regulation; Glutamic Acid; Humans; Mice; Molecular Sequence Data | 1999 |
Total plasma homocysteine as part of the routine aminogram by ion-exchange chromatography.
Topics: Amino Acids; Blood Chemical Analysis; Chromatography, Ion Exchange; Cysteine; Dithiothreitol; Glutamic Acid; Glutamine; Homocysteine; Humans; Time Factors | 1998 |
[Protective effect of neurotrophin against glutamate neurotoxicity in cortical cultures].
Topics: Animals; Brain-Derived Neurotrophic Factor; Cells, Cultured; Cerebral Cortex; Cysteine; Glutamic Acid; Ionomycin; Ionophores; Nerve Growth Factors; Neurons; Nitroso Compounds; Rats; S-Nitrosothiols | 1998 |
NMDAR channel segments forming the extracellular vestibule inferred from the accessibility of substituted cysteines.
Topics: Amino Acid Sequence; Animals; Calcium; Cell Membrane Permeability; Cysteine; Cytoplasm; Extracellular Space; Glutamic Acid; Indicators and Reagents; Membrane Potentials; Mesylates; Molecular Sequence Data; Mutation; Oocytes; Patch-Clamp Techniques; Receptors, N-Methyl-D-Aspartate; Xenopus | 1999 |
Seven novel mutations in the adenosine deaminase (ADA) gene in patients with severe and delayed onset combined immunodeficiency: G74C, V129M, G140E, R149W, Q199P, 462delG, and E337del. Mutations in brief no. 142. Online.
Topics: Adenosine Deaminase; Adolescent; Adult; Age of Onset; Arginine; Cysteine; Glutamic Acid; Glutamine; Glycine; Humans; Methionine; Mutation; Proline; Sequence Deletion; Severe Combined Immunodeficiency; Tryptophan; Valine | 1998 |
Glutamate regulates IP3-type and CICR stores in the avian cochlear nucleus.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Alanine; Animals; Benzoates; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Chelating Agents; Chick Embryo; Cochlear Nucleus; Cyclic AMP; Cycloleucine; Cysteine; Egtazic Acid; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Fura-2; Gallic Acid; Glutamic Acid; Glycine; Ibotenic Acid; Inositol 1,4,5-Trisphosphate Receptors; Ion Channel Gating; Neurons; Neuroprotective Agents; Neurotransmitter Agents; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Receptors, Cytoplasmic and Nuclear; Ryanodine; Second Messenger Systems; Thionucleotides | 1999 |
Metabolism of glutathione in isolated non filtering rat kidneys.
Topics: Animals; Cysteine; Glutamic Acid; Glutathione; Glutathione Disulfide; Glycine; Kidney; Male; Oxidation-Reduction; Perfusion; Rats; Rats, Inbred WKY | 1998 |
Proximity between Glu126 and Arg144 in the lactose permease of Escherichia coli.
Topics: Amino Acid Sequence; Arginine; Binding Sites; Cysteine; Electron Spin Resonance Spectroscopy; Escherichia coli; Escherichia coli Proteins; Glutamic Acid; Histidine; Manganese; Membrane Transport Proteins; Molecular Sequence Data; Monosaccharide Transport Proteins; Mutagenesis, Site-Directed; Spectrometry, Fluorescence; Spin Labels; Symporters | 1999 |
Evidence of glutathione transporter in rat brain synaptosomal membrane vesicles.
Topics: Animals; Biological Transport; Carrier Proteins; Cerebral Cortex; Cysteine; Glutamic Acid; Glutathione; Glycine; Male; Membrane Potentials; Membrane Transport Proteins; Rats; Rats, Wistar; Synaptic Membranes; Synaptosomes | 1999 |
Glutamyl substrate-induced exposure of a free cysteine residue in the vitamin K-dependent gamma-glutamyl carboxylase is critical for vitamin K epoxidation.
Topics: Amino Acid Sequence; Animals; Binding Sites; Carbon-Carbon Ligases; Cysteine; Enzyme Activation; Epoxy Compounds; Ethylmaleimide; Glutamic Acid; Humans; Molecular Sequence Data; Oligopeptides; Peptides; Protein Precursors; Substrate Specificity; Sulfhydryl Reagents; Vitamin K | 1999 |
Mutants that alter the covalent structure of catalase hydroperoxidase II from Escherichia coli.
Topics: Amino Acid Sequence; Amino Acid Substitution; Base Sequence; Catalase; Crystallography, X-Ray; Cysteine; Escherichia coli; Genetic Variation; Glutamic Acid; Heme; Histidine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Protein Conformation; Recombinant Proteins; Restriction Mapping | 1999 |
The Glu632-Leu633 deletion in cysteine rich domain of Ret induces constitutive dimerization and alters the processing of the receptor protein.
Topics: 3T3 Cells; Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Animals; Cell Membrane; Cell Transformation, Neoplastic; Cysteine; Dimerization; Drosophila Proteins; Endoplasmic Reticulum; Glutamic Acid; Leucine; Mercaptoethanol; Mice; Phosphorylation; Polysaccharides; Precipitin Tests; Protein Precursors; Protein Processing, Post-Translational; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ret; Receptor Protein-Tyrosine Kinases; Sequence Deletion; Shc Signaling Adaptor Proteins; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1 | 1999 |
Inhibitors of mitochondrial respiration, iron (II), and hydroxyl radical evoke release and extracellular hydrolysis of glutathione in rat striatum and substantia nigra: potential implications to Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Corpus Striatum; Cysteine; Glutamic Acid; Glutathione; Glycine; Hydrolysis; Hydroxyl Radical; Iron; Kinetics; Male; Microdialysis; Mitochondria; Models, Chemical; Nitro Compounds; Oxygen Consumption; Parkinson Disease; Perfusion; Propionates; Rats; Rats, Sprague-Dawley; Substantia Nigra | 1999 |
Molecular defects in variant forms of mannose-binding protein associated with immunodeficiency.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Arginine; Aspartic Acid; Carrier Proteins; Collectins; Complement Fixation Tests; Cysteine; Disulfides; Glutamic Acid; Glycine; Humans; Immunologic Deficiency Syndromes; Mannans; Molecular Sequence Data; Point Mutation; Protein Processing, Post-Translational; Rats | 1999 |
Mutations in the rod outer segment membrane guanylate cyclase in a cone-rod dystrophy cause defects in calcium signaling.
Topics: Animals; Arginine; Aspartic Acid; Calcium Signaling; Calcium-Binding Proteins; Cattle; Cysteine; Enzyme Activation; Glutamic Acid; Guanylate Cyclase; Guanylate Cyclase-Activating Proteins; Humans; Mutagenesis, Insertional; Protein Binding; Receptors, Cell Surface; Retinal Degeneration; Rod Cell Outer Segment; S100 Proteins | 1999 |
Evidence for endogenous excitatory amino acids as mediators in DSI of GABA(A)ergic transmission in hippocampal CA1.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cysteine; Evoked Potentials; Excitatory Amino Acids; Glutamic Acid; Hippocampus; Homocysteine; In Vitro Techniques; Male; Neurotransmitter Agents; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Synaptic Transmission | 1999 |
Streptolysin O: inhibition of the conformational change during membrane binding of the monomer prevents oligomerization and pore formation.
Topics: Alanine; Allosteric Regulation; Animals; Asparagine; Bacterial Proteins; Cysteine; Erythrocyte Membrane; Glutamic Acid; Lipid Bilayers; Membrane Proteins; Mutagenesis, Site-Directed; Point Mutation; Protein Binding; Protein Conformation; Rabbits; Sheep; Spectrometry, Fluorescence; Streptolysins; Temperature | 1999 |
Membrane assembly of the 16-kDa proteolipid channel from Nephrops norvegicus studied by relaxation enhancements in spin-label ESR.
Topics: Animals; Cations, Divalent; Cyclic N-Oxides; Cysteine; Dicyclohexylcarbodiimide; Digestive System; Electron Spin Resonance Spectroscopy; Glutamic Acid; Ion Channels; Membranes; Molecular Weight; Nephropidae; Nickel; Proteolipids; Spin Labels | 1999 |
A conserved serine-rich stretch in the glutamate transporter family forms a substrate-sensitive reentrant loop.
Topics: Amino Acid Motifs; Amino Acid Sequence; Amino Acid Transport System X-AG; ATP-Binding Cassette Transporters; Conserved Sequence; Cysteine; Ethylmaleimide; Glutamic Acid; Molecular Sequence Data; Serine | 1999 |
Growth of kerosene-biodegrading microorganisms in the presence of alpha-amino acid.
Topics: Amino Acids; Animals; Arginine; Biodegradation, Environmental; Carbon; Cysteine; Glutamic Acid; Kerosene; Nitrogen; Soil Microbiology; Soil Pollutants; Stereoisomerism; Wool | 1999 |
Specific glutathione binding sites in pig cerebral cortical synaptic membranes.
Topics: Animals; Binding Sites; Cerebral Cortex; Cysteine; Dipeptides; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glutathione; Glycine; Kynurenic Acid; Ligands; Neurons; Radioligand Assay; Receptors, GABA; Receptors, Glutamate; Receptors, Peptide; Signal Transduction; Swine; Synaptic Membranes; Tritium | 2000 |
Two novel mutations consisting in minor gene rearrangements in the human low density lipoprotein receptor gene in Italian patients affected by familial hypercholesterolemia. Mutations in brief no. 194. Online.
Topics: Amino Acid Substitution; Cysteine; Frameshift Mutation; Glutamic Acid; Humans; Hyperlipoproteinemia Type II; Italy; Lysine; Receptors, LDL | 1998 |
Identification of threonine residues controlling the agonist-dependent phosphorylation and desensitization of the rat A(3) adenosine receptor.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; CHO Cells; Cricetinae; Cysteine; Glutamic Acid; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphorylation; Purinergic P1 Receptor Agonists; Rats; Receptor, Adenosine A3; Receptors, Purinergic P1; Sequence Homology, Amino Acid; Threonine | 2000 |
Potentiation by L-cysteine of N-methyl-D-aspartate receptor: effects on intracellular free Ca2+ in cultured cerebellar granule cells.
Topics: Animals; Calcium; Calcium Radioisotopes; Cell Membrane; Cells, Cultured; Cerebellum; Cysteine; Excitatory Amino Acid Agonists; Glutamic Acid; N-Methylaspartate; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Zinc | 1999 |
Investigation of spectroscopic intermediates during copper-binding and TPQ formation in wild-type and active-site mutants of a copper-containing amine oxidase from yeast.
Topics: Amine Oxidase (Copper-Containing); Asparagine; Aspartic Acid; Binding Sites; Coenzymes; Copper; Cysteine; Dihydroxyphenylalanine; Glutamic Acid; Glutamine; Histidine; Mutagenesis, Site-Directed; Oxygen Consumption; Pichia; Recombinant Proteins; Spectrophotometry, Atomic; Spectrophotometry, Ultraviolet | 2000 |
Thiol cross-linking of transmembrane domains IV and V in the lactose permease of Escherichia coli.
Topics: Amino Acid Sequence; Arginine; Cross-Linking Reagents; Cysteine; Escherichia coli; Escherichia coli Proteins; Factor Xa; Glutamic Acid; Membrane Proteins; Membrane Transport Proteins; Molecular Sequence Data; Monosaccharide Transport Proteins; Mutagenesis, Site-Directed; Peptide Fragments; Protein Structure, Secondary; Protein Structure, Tertiary; Sulfhydryl Compounds; Symporters | 2000 |
Structural and biochemical investigations of the catalytic mechanism of an NADP-dependent aldehyde dehydrogenase from Streptococcus mutans.
Topics: Acylation; Aldehyde Dehydrogenase; Amino Acid Substitution; Apoenzymes; Binding Sites; Catalysis; Crystallography, X-Ray; Cysteine; Glutamic Acid; Holoenzymes; Hydrogen Bonding; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Molecular Sequence Data; Mutation; NADP; Pliability; Protein Conformation; Streptococcus mutans; Sulfates | 2000 |
Cryptic dimer interface and domain organization of the extracellular region of metabotropic glutamate receptor subtype 1.
Topics: Alanine; Amino Acid Substitution; Animals; Arginine; Cell Line; Cysteine; Dimerization; Female; Glutamic Acid; In Vitro Techniques; Kinetics; Ligands; Mutagenesis, Site-Directed; Oocytes; Point Mutation; Quisqualic Acid; Receptors, Metabotropic Glutamate; Recombinant Proteins; Spodoptera; Transfection; Xenopus laevis | 2000 |
Impaired secretion of rat mannose-binding protein resulting from mutations in the collagen-like domain.
Topics: Amino Acid Substitution; Animals; Arginine; Aspartic Acid; Carrier Proteins; CHO Cells; Collagen; Collectins; Complement Fixation Tests; Cricetinae; Cysteine; Endoplasmic Reticulum; Glutamic Acid; Glycine; Humans; Lectins; Lysine; Mannans; Mutagenesis, Site-Directed; Protein Processing, Post-Translational; Protein Structure, Tertiary; Proteins; Rats; Time Factors; Transfection | 2000 |
Ligand--protein interactions in the glutamate receptor.
Topics: Binding Sites; Cysteine; Glutamic Acid; Kainic Acid; Ligands; Protein Structure, Secondary; Protein Structure, Tertiary; Receptors, AMPA; Solutions; Spectroscopy, Fourier Transform Infrared | 2000 |
Altered intestinal transport of amino acids in cirrhotic rats: the effect of insulin-like growth factor-I.
Topics: Amino Acids; Animals; Cysteine; Glutamic Acid; Insulin-Like Growth Factor I; Intestinal Absorption; Jejunum; Kinetics; Leucine; Liver Cirrhosis, Experimental; Malabsorption Syndromes; Male; Microvilli; Nutrition Disorders; Proline; Rats; Rats, Wistar | 2000 |
Inhibition of glutamate uptake by Tx3-4 is dependent on the redox state of cysteine residues.
Topics: 4-Chloromercuribenzenesulfonate; Animals; Biological Transport; Cysteine; Dithionitrobenzoic Acid; Dithiothreitol; Glutamic Acid; Hippocampus; Neuropeptides; Neurotoxins; Oxidation-Reduction; Rats; Rats, Wistar; Spider Venoms; Synaptosomes | 2000 |
A structure-function study of a proton transport pathway in the gamma-class carbonic anhydrase from Methanosarcina thermophila.
Topics: Alanine; Amino Acid Substitution; Aspartic Acid; Biological Transport; Carbonic Anhydrases; Cysteine; Deuterium; Escherichia coli; Genetic Variation; Glutamic Acid; Glutamine; Histidine; Hydrogen-Ion Concentration; Kinetics; Lysine; Methanosarcina; Mutagenesis, Site-Directed; Protons; Serine; Solvents; Structure-Activity Relationship; Threonine; Tryptophan | 2000 |
Side chain orientation in the selectivity filter of a voltage-gated Ca2+ channel.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Cadmium; Calcium Channels, L-Type; Cysteine; Electric Conductivity; Glutamic Acid; Ion Channel Gating; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Oocytes; Patch-Clamp Techniques; Protein Conformation; Substrate Specificity; Sulfhydryl Reagents; Thiosulfonic Acids; Xenopus laevis | 2000 |
Site-directed ligand discovery.
Topics: Amino Acid Substitution; Binding Sites; Crystallography, X-Ray; Cysteine; Disulfides; Drug Design; Escherichia coli; Glutamic Acid; Ligands; Models, Molecular; Molecular Weight; Peptide Library; Proline; Protein Conformation; Protein Engineering; Thermodynamics; Thymidylate Synthase | 2000 |
Catalytic control and coupling efficiency of the Escherichia coli FoF1 ATP synthase: influence of the Fo sector and epsilon subunit on the catalytic transition state.
Topics: Adenosine Triphosphate; Amino Acid Substitution; Biological Transport; Catalysis; Cysteine; Detergents; Dimethylamines; Enzyme Activation; Escherichia coli; Glutamic Acid; Hydrolysis; Kinetics; Lysine; Methionine; Mutagenesis, Site-Directed; Peptide Fragments; Proton-Translocating ATPases; Protons; Tyrosine | 2000 |
The conserved cysteine 7.38 residue is differentially accessible in the binding-site crevices of the mu, delta, and kappa opioid receptors.
Topics: Amino Acid Sequence; Animals; Benzomorphans; Binding Sites; Cell Line; Conserved Sequence; Cysteine; Diprenorphine; Dose-Response Relationship, Drug; Ethyl Methanesulfonate; Glutamic Acid; Humans; Indicators and Reagents; Mesylates; Methionine; Molecular Sequence Data; Mutagenesis, Site-Directed; Naloxone; Narcotic Antagonists; Protein Structure, Secondary; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Serine; Time Factors; Tritium | 2000 |
Characterization of electrically evoked [3H]-D-aspartate release from hippocampal slices.
Topics: Animals; Aspartic Acid; Calcium; Cysteine; Diffusion Chambers, Culture; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; In Vitro Techniques; Magnesium; Neurotransmitter Agents; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Stereoisomerism; Tritium | 2001 |
Tec kinase signaling in T cells is regulated by phosphatidylinositol 3-kinase and the Tec pleckstrin homology domain.
Topics: Amino Acid Substitution; Androstadienes; Animals; Arginine; Blood Proteins; Cysteine; Enzyme Inhibitors; Glutamic Acid; Humans; Interleukin-2; Jurkat Cells; Lysine; Mice; Mice, Transgenic; Phosphatidylinositol 3-Kinases; Phosphatidylinositol Phosphates; Phosphoinositide-3 Kinase Inhibitors; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Binding; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Receptor-CD3 Complex, Antigen, T-Cell; Receptors, Antigen, T-Cell; Sequence Homology, Amino Acid; Signal Transduction; T-Lymphocytes; Transfection; Wortmannin | 2001 |
Identification of active site residues in E. coli ketopantoate reductase by mutagenesis and chemical rescue.
Topics: Acetic Acid; Alanine; Alcohol Oxidoreductases; Alkylation; Amino Acid Sequence; Bacterial Proteins; Binding Sites; Cysteine; Deuterium; Escherichia coli; Formates; Gene Expression Regulation, Bacterial; Glutamic Acid; Kinetics; Lysine; Molecular Sequence Data; Pantothenic Acid; Recombinant Proteins; Sequence Alignment; Substrate Specificity | 2000 |
Construction, separation and properties of hybrid hexamers of glutamate dehydrogenase in which five of the six subunits are contributed by the catalytically inert D165S.
Topics: Allosteric Regulation; Allosteric Site; Amino Acid Substitution; Catalysis; Chromatography, Affinity; Clostridium; Coloring Agents; Cysteine; Dithionitrobenzoic Acid; Glutamate Dehydrogenase; Glutamic Acid; Hydrogen-Ion Concentration; Kinetics; Ligands; Mutation; NAD; Protein Denaturation; Protein Folding; Protein Renaturation; Protein Structure, Quaternary; Protein Subunits; Recombinant Fusion Proteins; Triazines; Ultrafiltration; Urea | 2001 |
The Venus's-flytrap and cysteine-rich domains of the human Ca2+ receptor are not linked by disulfide bonds.
Topics: Amino Acid Sequence; Binding Sites; Calcium-Binding Proteins; Cell Line; Cysteine; Dimerization; Disulfides; Dose-Response Relationship, Drug; Endopeptidases; Glutamic Acid; Humans; Immunoblotting; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Conformation; Protein Sorting Signals; Protein Structure, Tertiary; Transfection; Valine | 2001 |
Factors that control the reactivity of the interface cysteine of triosephosphate isomerase from Trypanosoma brucei and Trypanosoma cruzi.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Cysteine; Dimerization; Enzyme Activation; Enzyme Inhibitors; Glutamic Acid; Glutamine; Glycolates; Hydrogen-Ion Concentration; Leishmania mexicana; Methyl Methanesulfonate; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Proline; Protein Structure, Tertiary; Triose-Phosphate Isomerase; Trypanosoma brucei brucei; Trypanosoma cruzi | 2001 |
Chemical mechanism and substrate binding sites of NADP-dependent aldehyde dehydrogenase from Streptococcus mutans.
Topics: Acylation; Aldehyde Oxidoreductases; Catalytic Domain; Crystallography, X-Ray; Cysteine; Enzyme Activation; Glutamic Acid; Glyceraldehyde 3-Phosphate; Hydrolysis; Models, Molecular; Point Mutation; Protein Conformation; Streptococcus mutans; Substrate Specificity | 2001 |
Crystal structure of 3,4-dihydroxy-2-butanone 4-phosphate synthase of riboflavin biosynthesis.
Topics: Aspartic Acid; Binding Sites; Catalysis; Crystallography, X-Ray; Cysteine; Dimerization; Escherichia coli; Glutamic Acid; Histidine; Intramolecular Transferases; Magnesium; Models, Chemical; Models, Molecular; Protein Structure, Secondary; Riboflavin; Riboflavin Synthase | 2001 |
Simultaneous determination of several amino acids, including homocysteine, cysteine and glutamic acid, in human plasma by isocratic reversed-phase high-performance liquid chromatography with fluorimetric detection.
Topics: Cardiovascular Diseases; Chromatography, High Pressure Liquid; Cysteine; Glutamic Acid; Homocysteine; Humans; o-Phthalaldehyde; Sensitivity and Specificity; Spectrometry, Fluorescence | 2001 |
Biochemical characterization and identification of catalytic residues in alpha-glucuronidase from Bacillus stearothermophilus T-6.
Topics: Alanine; Amino Acid Sequence; Aspartic Acid; Binding Sites; Calorimetry, Differential Scanning; Catalysis; Catalytic Domain; Chromatography, Gel; Cysteine; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Geobacillus stearothermophilus; Glutamic Acid; Glycoside Hydrolases; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Binding; Sequence Analysis, Protein; Sequence Homology, Amino Acid; Temperature; Trioses | 2001 |
Channel-lining residues of the AMPA receptor M2 segment: structural environment of the Q/R site and identification of the selectivity filter.
Topics: Amino Acid Substitution; Animals; Calcium; Cysteine; Cytoplasm; Dose-Response Relationship, Drug; Ethyl Methanesulfonate; Glutamic Acid; Ion Channel Gating; Kainic Acid; Kinetics; Membrane Potentials; Mesylates; Microinjections; Mutagenesis, Site-Directed; Oocytes; Patch-Clamp Techniques; Permeability; Receptors, AMPA; Structure-Activity Relationship; Sulfhydryl Reagents; Xenopus laevis | 2001 |
Sulphur nutrition affects delivery and metabolism of S in developing endosperms of wheat.
Topics: Adenosine Triphosphate; Cysteine; Cysteine Synthase; Glutamate-Cysteine Ligase; Glutamic Acid; Glutathione; Glycine; Nitrogen; Seeds; Sulfates; Sulfur; Triticum | 2001 |
beta-Ketoacyl-[acyl carrier protein] synthase I of Escherichia coli: aspects of the condensation mechanism revealed by analyses of mutations in the active site pocket.
Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase; Aspartic Acid; Binding Sites; Carboxy-Lyases; Catalysis; Chromatography; Cysteine; DNA; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Glutamic Acid; Glutamine; Histidine; Hydrogen-Ion Concentration; Isoenzymes; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Myristic Acid; Plasmids; Protein Binding; Recombinant Proteins | 2001 |
Evidence for redundancy in cysteine biosynthesis in Rhizobium leguminosarum RL3841: analysis of a cysE gene encoding serine acetyltransferase.
Topics: Acetyltransferases; Amino Acid Sequence; Base Sequence; Cloning, Molecular; Cysteine; DNA, Bacterial; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Genes, Bacterial; Glutamic Acid; Molecular Sequence Data; Mutation; Nitrogen Fixation; Phylogeny; Rhizobium leguminosarum; Sequence Homology, Amino Acid; Serine O-Acetyltransferase | 2001 |
The covalent structure of the small subunit from Pseudomonas putida amine dehydrogenase reveals the presence of three novel types of internal cross-linkages, all involving cysteine in a thioether bond.
Topics: Amino Acid Sequence; Amino Acids; Cloning, Molecular; Cross-Linking Reagents; Cysteine; Glutamic Acid; Heme; Indolequinones; Mass Spectrometry; Models, Chemical; Models, Genetic; Molecular Sequence Data; Open Reading Frames; Oxidation-Reduction; Oxidoreductases Acting on CH-NH Group Donors; Peptides; Protein Binding; Protein Processing, Post-Translational; Pseudomonas putida; Quinones; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Spectrometry, Mass, Electrospray Ionization; Sulfides; Tryptophan; X-Rays | 2001 |
Synthesis and biochemical characterization of a phosphorylated analogue of the response regulator CheB.
Topics: Aspartic Acid; Bacterial Proteins; Catalytic Domain; Chromatography, High Pressure Liquid; Cysteine; Escherichia coli; Esterases; Glutamic Acid; Glutamine; Magnesium; Mass Spectrometry; Methylation; Models, Chemical; Mutagenesis, Site-Directed; Mutation; Phosphates; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Signal Transduction; Time Factors | 2001 |
Crystal structure of quinohemoprotein amine dehydrogenase from Pseudomonas putida. Identification of a novel quinone cofactor encaged by multiple thioether cross-bridges.
Topics: Amino Acids; Aspartic Acid; Binding Sites; Catalytic Domain; Crystallography, X-Ray; Cysteine; Dipeptides; Glutamic Acid; Indolequinones; Models, Molecular; Oxidoreductases Acting on CH-NH Group Donors; Protein Conformation; Protein Folding; Protein Structure, Tertiary; Pseudomonas putida; Quinones; Sulfides | 2002 |
Two glutamic acids in chitosanase A from Matsuebacter chitosanotabidus 3001 are the catalytically important residues.
Topics: Bacterial Proteins; Catalytic Domain; Circular Dichroism; Cysteine; Disulfides; Glutamic Acid; Glycoside Hydrolases; Kinetics; Mutagenesis; Oligosaccharides; Point Mutation; Proteobacteria; Sequence Alignment | 2002 |
Specificity determining residues in ammonia- and glutamine-dependent carbamoyl phosphate synthetases.
Topics: Adenosine Triphosphate; Allosteric Site; Amino Acid Sequence; Ammonia; Animals; Binding Sites; Blotting, Western; Carbamoyl-Phosphate Synthase (Ammonia); Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Cysteine; Escherichia coli; Glutamic Acid; Glutamine; Humans; Kinetics; Leucine; Lysine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Plasmids; Protein Binding; Protein Structure, Tertiary; Ranidae; Rats; Recombinant Proteins; Substrate Specificity | 2002 |
Molecular rearrangements of the extracellular vestibule in NMDAR channels during gating.
Topics: Aminacrine; Animals; Cell Membrane; Central Nervous System; Cysteine; Drug Interactions; Excitatory Amino Acid Antagonists; Extracellular Space; Female; Glutamic Acid; Ion Channel Gating; Membrane Potentials; Mutagens; Mutation; Oocytes; Protein Structure, Tertiary; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Xenopus laevis | 2002 |
GTP hydrolysis of cell division protein FtsZ: evidence that the active site is formed by the association of monomers.
Topics: Amino Acid Sequence; Bacterial Proteins; Binding Sites; Calcium; Cysteine; Cytoskeletal Proteins; Dose-Response Relationship, Drug; Escherichia coli; Glutamic Acid; GTP Phosphohydrolases; Guanosine Triphosphate; Hydrolysis; Light; Magnesium; Microscopy, Electron; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Scattering, Radiation; Sequence Homology, Amino Acid; Time Factors | 2002 |
Twists and turns of the cation-dependent mannose 6-phosphate receptor. Ligand-bound versus ligand-free receptor.
Topics: Amino Acid Sequence; Binding Sites; Circular Dichroism; Cysteine; Cytoplasm; Dimerization; Endosomes; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Ligands; Models, Molecular; Molecular Sequence Data; Phosphates; Protein Binding; Protein Conformation; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Receptor, IGF Type 2; Sequence Homology, Amino Acid | 2002 |
Importance of Na,K-ATPase residue alpha 1-Arg544 in the segment Arg544-Asp567 for high-affinity binding of ATP, ADP, or MgATP.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Alanine; Amino Acid Substitution; Animals; Arginine; Asparagine; Aspartic Acid; Binding Sites; Conserved Sequence; Cysteine; Glutamic Acid; Magnesium; Mutagenesis, Site-Directed; Peptide Fragments; Phosphorylation; Saccharomyces cerevisiae; Serine; Sodium-Potassium-Exchanging ATPase; Swine; Thermodynamics | 2002 |
A comparison in normal individuals and sickle cell patients of reduced glutathione precursors and their transport between plasma and red cells.
Topics: Adult; Amino Acid Transport System ASC; Amino Acid Transport System L; Anemia, Sickle Cell; Biological Transport; Carbon Monoxide; Cysteine; Enzyme Inhibitors; Erythrocytes; Female; Glutamic Acid; Glutamine; Glutathione; Glycine; Humans; Male; Middle Aged; Oxygen; Protein Kinase Inhibitors; Protein Kinases; Serine; Staurosporine | 2000 |
Superoxide modification and inactivation of a neuronal receptor-like complex.
Topics: Animals; Cysteine; Ethylmaleimide; Glutamic Acid; Membrane Proteins; N-Methylaspartate; Point Mutation; Protein Binding; Rats; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate; Superoxides; Synaptic Membranes; Tritium; Xanthine; Xanthine Oxidase | 2002 |
Hydrogen sulfide is produced in response to neuronal excitation.
Topics: Animals; Binding Sites; Brain Chemistry; Calcium; Calmodulin; Cerebral Cortex; COS Cells; Cystathionine beta-Synthase; Cysteine; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Glutamic Acid; Hydrogen Sulfide; In Vitro Techniques; Ionophores; Long-Term Potentiation; Mice; Mice, Knockout; Neurons; Precipitin Tests; Protein Binding; Signal Transduction; Synaptic Transmission; Transfection | 2002 |
Cysteine-scanning mutagenesis reveals a conformationally sensitive reentrant pore-loop in the glutamate transporter GLT-1.
Topics: Amino Acid Substitution; Biotin; Cysteine; Excitatory Amino Acid Transporter 2; Glutamic Acid; HeLa Cells; Humans; Indicators and Reagents; Kainic Acid; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation; Protein Structure, Secondary; Sodium; Structure-Activity Relationship | 2002 |
Enthalpic homogeneous pair interaction coefficients of L-alpha-amino acids as a hydrophobicity parameter of amino acid side chains.
Topics: Amino Acids; Arginine; Asparagine; Calorimetry; Cysteine; Glutamic Acid; Glutamine; Histidine; Solutions; Stereoisomerism; Thermodynamics; Tryptophan; Water | 2002 |
Activation of the plant mitochondrial alternative oxidase: insights from site-directed mutagenesis.
Topics: Adenosine Triphosphate; Amino Acid Substitution; Arabidopsis; Catalysis; Cysteine; Dimerization; Enzyme Activation; Escherichia coli; Glutamic Acid; Glyoxylates; Mitochondria; Mitochondrial Proteins; Mutagenesis, Site-Directed; Oxidoreductases; Oxygen; Plant Proteins; Protein Conformation; Pyruvic Acid; Sequence Analysis, DNA; Serine; Structure-Activity Relationship; Succinic Acid; Water | 2002 |
Non-essential roles of cysteine residues in functional expression and redox regulatory pathways for canine glutamate/aspartate transporter based on mutagenic analysis.
Topics: Amino Acid Transport System X-AG; Animals; Biological Transport; Cell Membrane; Cloning, Molecular; COS Cells; Cysteine; Dithiothreitol; DNA, Complementary; Dogs; Glutamic Acid; Kinetics; Mercury; Microscopy, Fluorescence; Mutagenesis, Site-Directed; Mutation; Oxidation-Reduction; Oxygen; Sodium; Telencephalon; Time Factors; Transfection | 2002 |
An essential role of N-terminal arginylation in cardiovascular development.
Topics: Alkylation; Aminoacyltransferases; Animals; Aorta; Arginine; Aspartic Acid; Blood Vessels; Cell Line; Cysteic Acid; Cysteine; Female; Glutamic Acid; Heart; Heart Defects, Congenital; Heart Septal Defects; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Mice; Mice, Inbred C57BL; Neovascularization, Physiologic; Oxidation-Reduction; Proteins; Pulmonary Artery; Recombinant Proteins; RGS Proteins; Sulfinic Acids; Transcription Factors; Transfection | 2002 |
Evidence of a critical architectural function for the RAG proteins in end processing, protection, and joining in V(D)J recombination.
Topics: Alanine; Amino Acid Substitution; Animals; Cell Line; Cysteine; DNA; DNA Nucleotidyltransferases; DNA-Binding Proteins; Gene Rearrangement, B-Lymphocyte; Genes, RAG-1; Glutamic Acid; Homeodomain Proteins; Humans; Macromolecular Substances; Mice; Mutagenesis, Site-Directed; Nuclear Proteins; Nucleic Acid Conformation; Phenotype; Protein Interaction Mapping; Recombinant Fusion Proteins; Recombination, Genetic; Regulatory Sequences, Nucleic Acid; Serine; Substrate Specificity; VDJ Recombinases | 2002 |
Stimulatory and inhibitory effects of protein amino acids on growth rate and efficiency of mixed ruminal bacteria.
Topics: Amino Acids; Ammonia; Animals; Bacteria; Cattle; Cellobiose; Cysteine; Female; Glucose; Glutamic Acid; Glutamine; Isoleucine; Leucine; Nitrogen; Phenylalanine; Rumen; Xylose | 2002 |
The catalytic mechanism of the ESA1 histone acetyltransferase involves a self-acetylated intermediate.
Topics: Acetylation; Acetyltransferases; Catalysis; Crystallography, X-Ray; Cysteine; Escherichia coli; Glutamic Acid; Histone Acetyltransferases; Histones; Mass Spectrometry; Recombinant Proteins; Saccharomyces cerevisiae Proteins | 2002 |
Glutamate 172, essential for modulation of L247T alpha7 ACh receptors by Ca2+, lines the extracellular vestibule.
Topics: Acetylcholine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Barium; Calcium; Cysteine; Extracellular Space; Glutamic Acid; Membrane Potentials; Mutagenesis; Oocytes; Patch-Clamp Techniques; Protein Structure, Tertiary; Receptors, Nicotinic; Strontium; Water; Xenopus laevis | 2002 |
Initial characterization of the glutamate-cysteine ligase modifier subunit Gclm(-/-) knockout mouse. Novel model system for a severely compromised oxidative stress response.
Topics: Age Factors; Alleles; Animals; Blotting, Northern; Blotting, Southern; Body Weight; Cell Death; Chromatography, Gel; Cysteine; Dose-Response Relationship, Drug; Fibroblasts; Genotype; Glutamate-Cysteine Ligase; Glutamic Acid; Glutathione; Homozygote; Hydrogen Peroxide; Immunoblotting; Kidney; Kinetics; Liver; Mice; Mice, Knockout; Models, Genetic; Mutagenesis, Site-Directed; Oxidative Stress; Oxygen; Phenotype; Polymerase Chain Reaction; Protein Structure, Tertiary; Time Factors; Tissue Distribution | 2002 |
Autolytic processing at Glu586-Ser587 within the cysteine-rich domain of human adamalysin 19/disintegrin-metalloproteinase 19 is necessary for its proteolytic activity.
Topics: ADAM Proteins; Animals; Base Sequence; Cell Line; Cysteine; Disintegrins; DNA Primers; Glutamic Acid; Humans; Hydrolysis; Kinetics; Membrane Proteins; Metalloendopeptidases; Metalloproteases; Muscle Proteins; Mutagenesis; Protein Processing, Post-Translational; Serine; Substrate Specificity; Tetradecanoylphorbol Acetate | 2002 |
The beta G156C substitution in the F1-ATPase from the thermophilic Bacillus PS3 affects catalytic site cooperativity by destabilizing the closed conformation of the catalytic site.
Topics: Adenosine Triphosphate; Amino Acid Substitution; Bacillus; Binding Sites; Catalysis; Catalytic Domain; Cysteine; Dimethylamines; Enzyme Stability; Glutamic Acid; Glycine; Hydrolysis; Magnesium; Mutagenesis, Site-Directed; Protein Conformation; Proton-Translocating ATPases; Sodium Azide; Tryptophan; Tyrosine; Valine | 2002 |
Staggering of subunits in NMDAR channels.
Topics: Aminacrine; Amino Acid Sequence; Animals; Cations; Cell Membrane; Cells, Cultured; Cysteine; Extracellular Space; Female; Glutamic Acid; Ion Channel Gating; Ion Channels; Macromolecular Substances; Membrane Potentials; Mesylates; Molecular Sequence Data; Mutagenesis, Site-Directed; Oocytes; Protein Conformation; Protein Subunits; Receptors, N-Methyl-D-Aspartate; Sequence Homology, Amino Acid; Silver; Xenopus | 2002 |
Structural and thermodynamic studies on a salt-bridge triad in the NADP-binding domain of glutamate dehydrogenase from Thermotoga maritima: cooperativity and electrostatic contribution to stability.
Topics: Alanine; Arginine; Binding Sites; Crystallography, X-Ray; Cysteine; Enzyme Stability; Glutamate Dehydrogenase; Glutamic Acid; Guanidine; Lysine; Mutagenesis, Site-Directed; NADP; Protein Denaturation; Protein Folding; Protein Structure, Tertiary; Recombinant Proteins; Salts; Serine; Static Electricity; Structure-Activity Relationship; Thermodynamics; Thermotoga maritima; Urea | 2002 |
Substrate recognition and molecular mechanism of fatty acid hydroxylation by cytochrome P450 from Bacillus subtilis. Crystallographic, spectroscopic, and mutational studies.
Topics: Arginine; Bacillus subtilis; Binding Sites; Crystallography, X-Ray; Cysteine; Cytochrome P-450 Enzyme System; Escherichia coli; Fatty Acids; Glutamic Acid; Histidine; Ligands; Magnetic Resonance Spectroscopy; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Myristic Acid; Oxygen; Protein Binding; Protein Conformation; Protein Folding; Protein Structure, Tertiary; Recombinant Proteins; Spectrophotometry; Spectrum Analysis, Raman; Substrate Specificity | 2003 |
The unusual catalytic triad of poliovirus protease 3C.
Topics: 3C Viral Proteases; Catalysis; Catalytic Domain; Cysteine; Cysteine Endopeptidases; Deuterium; Glutamic Acid; Glutamine; Glycine; Hydrogen-Ion Concentration; Kinetics; Methionine; Models, Chemical; Mutagenesis, Site-Directed; Poliovirus; Serine; Solvents; Substrate Specificity; Temperature; Thermodynamics; Viral Proteins | 2003 |
Catalytic mechanism of Escherichia coli isopentenyl diphosphate isomerase involves Cys-67, Glu-116, and Tyr-104 as suggested by crystal structures of complexes with transition state analogues and irreversible inhibitors.
Topics: Carbon-Carbon Double Bond Isomerases; Catalytic Domain; Crystallography; Cysteine; Epoxy Compounds; Escherichia coli; Glutamic Acid; Hemiterpenes; Kinetics; Organophosphorus Compounds; Protein Structure, Secondary; Tyrosine | 2003 |
Ruthenium red inhibits TASK-3 potassium channel by interconnecting glutamate 70 of the two subunits.
Topics: Animals; Arginine; Coloring Agents; Cysteine; Dimerization; Glutamic Acid; Humans; Lysine; Mice; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Potassium Channels; Potassium Channels, Tandem Pore Domain; Ruthenium Red | 2003 |
The glutamate transporters EAAT2 and EAAT3 mediate cysteine uptake in cortical neuron cultures.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Astrocytes; Binding, Competitive; Biological Transport; Cells, Cultured; Cerebral Cortex; Cysteine; Dose-Response Relationship, Drug; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Glutathione; Kainic Acid; Mice; Neurons; Sodium; Symporters | 2003 |
Metabotropic glutamate receptors activate phospholipase D in astrocytes through a protein kinase C-dependent and Rho-independent pathway.
Topics: ADP-Ribosylation Factors; Animals; Astrocytes; Bacterial Proteins; Bacterial Toxins; Brefeldin A; Cells, Cultured; Chelating Agents; Cysteine; DNA; Dose-Response Relationship, Drug; Egtazic Acid; Endothelin-1; Glutamic Acid; Indoles; Maleimides; Phospholipase D; Protein Kinase C; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; rho GTP-Binding Proteins; Stress Fibers; Sulfenic Acids; Tetradecanoylphorbol Acetate; Type C Phospholipases | 2003 |
Modeling zinc in biomolecules with the self consistent charge-density functional tight binding (SCC-DFTB) method: applications to structural and energetic analysis.
Topics: Alcohol Dehydrogenase; Algorithms; Aminopeptidases; Aspartic Acid; Bacterial Proteins; Binding Sites; Carbonic Anhydrases; Cysteine; Glutamic Acid; Histidine; Liver; Models, Molecular; Molecular Conformation; Protein Binding; Protein Conformation; Water; Zinc | 2003 |
Function of the loop residue Thr792 in human DNA topoisomerase II alpha.
Topics: Antigens, Neoplasm; Antineoplastic Agents; Catalysis; Cell Division; Cysteine; DNA Topoisomerases, Type II; DNA-Binding Proteins; DNA, Complementary; Dose-Response Relationship, Drug; Fungal Proteins; Genetic Complementation Test; Glutamic Acid; Glycine; Humans; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Plasmids; Poly-ADP-Ribose Binding Proteins; Saccharomyces cerevisiae; Serine; Threonine; Valine | 2003 |
Gonadotropin releasing hormone (GnRH) modulates odorant responses in the peripheral olfactory system of axolotls.
Topics: Ambystoma mexicanum; Animals; Cysteine; Dose-Response Relationship, Drug; Electrophysiology; Female; Glutamic Acid; Gonadotropin-Releasing Hormone; Lysine; Male; Methionine; Odorants; Olfactory Mucosa; Olfactory Receptor Neurons | 2003 |
The mechanism of Mycobacterium tuberculosis alkylhydroperoxidase AhpD as defined by mutagenesis, crystallography, and kinetics.
Topics: Antioxidants; Bacterial Proteins; Binding Sites; Catalysis; Catalytic Domain; Cell Division; Crystallography, X-Ray; Cysteine; Dimerization; Disulfides; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Mycobacterium tuberculosis; Oxygen; Peroxidases; Peroxiredoxins; Protein Conformation; Protons; Thioredoxins; Ultraviolet Rays | 2003 |
Eight amino acids form the ATP recognition site of Na(+)/K(+)-ATPase.
Topics: Adenosine Triphosphate; Amino Acids; Animals; Binding Sites; Brain; Cysteine; Dose-Response Relationship, Drug; Genetic Complementation Test; Genetic Vectors; Glutamic Acid; Glutamine; Hydrogen Bonding; Mice; Models, Molecular; Mutagenesis, Site-Directed; Phenylalanine; Point Mutation; Protein Binding; Protein Structure, Secondary; Recombinant Fusion Proteins; Recombinant Proteins; Sodium-Potassium-Exchanging ATPase; Spectrophotometry, Infrared; Spectroscopy, Fourier Transform Infrared | 2003 |
The reported human NADsyn2 is ammonia-dependent NAD synthetase from a pseudomonad.
Topics: Amide Synthases; Ammonia; Base Sequence; Chromosomes, Human, Pair 22; Cloning, Molecular; CpG Islands; Cysteine; DNA; Gene Library; Glutamic Acid; Glutamine; Humans; Hydrolysis; Molecular Sequence Data; Muscles; NAD; Nicotinamidase; Open Reading Frames; Operon; Phylogeny; Protein Structure, Tertiary; Pseudomonas; Sequence Homology, Nucleic Acid | 2003 |
Localization and functional characterization of metal-binding sites in phytochelatin synthases.
Topics: Amino Acid Sequence; Aminoacyltransferases; Arabidopsis; Binding Sites; Binding, Competitive; Cadmium; Chelating Agents; Cysteine; Gene Expression Regulation, Enzymologic; Glutamic Acid; Metals, Heavy; Molecular Sequence Data; Mutation; Plant Proteins; Protein Binding; Schizosaccharomyces; Sequence Homology, Amino Acid; Triticum | 2003 |
Molecular motions of the outer ring of charge of the sodium channel: do they couple to slow inactivation?
Topics: Amino Acid Substitution; Animals; Aspartic Acid; Cysteine; Electrophysiology; Glutamic Acid; Ion Channel Gating; Molecular Conformation; Muscle, Skeletal; Mutation; Oocytes; Phenanthrolines; Rats; Sodium Channels; Xenopus laevis | 2003 |
Neurotoxicity induced by amyloid beta-peptide and ibotenic acid in organotypic hippocampal cultures: protection by S-allyl-L-cysteine, a garlic compound.
Topics: Amino Acid Chloromethyl Ketones; Amyloid beta-Peptides; Animals; Cell Death; Cysteine; Dioxolanes; Drug Interactions; Excitatory Amino Acid Agonists; Garlic; Glutamic Acid; Hippocampus; Ibotenic Acid; Neurons; Neuroprotective Agents; Organ Culture Techniques; Purines; Rats; Rats, Wistar | 2003 |
The biological activity of mixtures of lycomarasmin and glutamic acid, glutamine glutathione, or cysteine.
Topics: Cysteine; Glutamates; Glutamic Acid; Glutamine; Glutathione; Peptides | 1953 |
[Study on the decarboxylation of L-cysteinesulfinic acid, L-cysteic acid, and L-glutamic acid by various organs of rabbits; influence of pyridoxal phosphate and thiol groups].
Topics: Animals; Aspartic Acid; Biochemical Phenomena; Coenzymes; Cysteic Acid; Cysteine; Decarboxylation; Glutamates; Glutamic Acid; Pyridoxal Phosphate; Rabbits; Sulfhydryl Compounds | 1956 |
[Influence of thyroxin injection on the decarboxylation of L-glutamic acid by rat brain and of L-cysteine-sulfinic acid by rat liver].
Topics: Animals; Brain; Cysteine; Decarboxylation; Glutamic Acid; Liver; Lyases; Rats; Sulfinic Acids; Thyroxine | 1958 |
THE REACTION OF THIOL AMINO ACIDS WITH PYRIDOXAL 5'-PHOSPHATE IN THE ABSENCE AND IN THE PRESENCE OF L-GLUTAMIC ACID.
Topics: Amino Acids; Chemical Phenomena; Chemistry; Cysteine; Glutamates; Glutamic Acid; Penicillamine; Phosphates; Pyridoxal Phosphate; Research; Sulfhydryl Compounds | 1963 |
GAS CHROMATOGRAPHY OF VOLATILE AMINO ACID DERIVATIVES. II. LEUCINE, CYSTEINE, PROLINE, HYDROXYPROLINE, METHIONINE, PHENYLALANINE, ASPARTIC ACID AND GLUTAMIC ACID.
Topics: Arginine; Aspartic Acid; Chromatography; Chromatography, Gas; Cysteine; Glutamates; Glutamic Acid; Hydroxyproline; Leucine; Methionine; Phenylalanine; Proline; Research | 1965 |
ACTION OF GLUTAMIC ACID AND OTHER NATURALLY OCCURRING AMINO-ACIDS ON SNAIL CENTRAL NEURONS.
Topics: Acetylcholine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Cysteine; Electrophysiology; Glutamates; Glutamic Acid; Helix, Snails; Iontophoresis; Neural Conduction; Neurons; Pharmacology; Research; Sensory Receptor Cells; Snails | 1964 |
The crystal structure of Escherichia coli heat shock protein YedU reveals three potential catalytic active sites.
Topics: Amino Acid Motifs; Amino Acid Sequence; Aspartic Acid; Binding Sites; Catalytic Domain; Crystallography, X-Ray; Cysteine; Dimerization; Electronic Data Processing; Escherichia coli Proteins; Glutamic Acid; Heat-Shock Proteins; Histidine; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Molecular Chaperones; Molecular Sequence Data; Protein Structure, Quaternary; Protein Structure, Tertiary; Recombinant Proteins; Sequence Homology, Amino Acid; Structural Homology, Protein; Zinc | 2003 |
Role of His-16 in turnover of T4 pyrimidine dimer glycosylase.
Topics: Alanine; Aspartic Acid; Cell Survival; Cysteine; Dimerization; DNA; DNA Glycosylases; DNA Repair; Escherichia coli; Glutamic Acid; Histidine; Kinetics; Lysine; Models, Biological; Mutagenesis, Site-Directed; Mutation; Oligonucleotides; Phenotype; Plasmids; Serine; Time Factors; Ultraviolet Rays | 2004 |
Role of neuronal glutamate transporter in the cysteine uptake and intracellular glutathione levels in cultured cortical neurons.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Blotting, Western; Cells, Cultured; Cerebral Cortex; Chromatography, High Pressure Liquid; Cysteine; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Extracellular Fluid; Glutamic Acid; Glutathione; Immunohistochemistry; Neurons; Rats; Sodium | 2003 |
A 193-amino acid fragment of the SARS coronavirus S protein efficiently binds angiotensin-converting enzyme 2.
Topics: Alanine; Angiotensin-Converting Enzyme 2; Carboxypeptidases; Cell Line; Cysteine; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Flow Cytometry; Glutamic Acid; Humans; Inhibitory Concentration 50; Membrane Glycoproteins; Mutation; Peptidyl-Dipeptidase A; Point Mutation; Protein Binding; Protein Structure, Tertiary; Severe acute respiratory syndrome-related coronavirus; Spike Glycoprotein, Coronavirus; Transfection; Viral Envelope Proteins | 2004 |
Detection of alpha-helical coiled-coil dimer formation by spin-labeled synthetic peptides: a model parallel coiled-coil peptide and the antiparallel coiled coil formed by a replica of the ProP C-terminus.
Topics: Amino Acid Sequence; Amino Acid Substitution; Cysteine; Dimerization; Electron Spin Resonance Spectroscopy; Escherichia coli Proteins; Glutamic Acid; Lysine; Models, Molecular; Molecular Sequence Data; Peptide Fragments; Peptides; Protein Structure, Secondary; Protein Structure, Tertiary; Spin Labels; Symporters | 2003 |
Class I ribonucleotide reductase revisited: the effect of removing a proton on Glu441.
Topics: Asparaginase; Binding Sites; Catalysis; Crystallography, X-Ray; Cysteine; Escherichia coli; Glutamic Acid; Hydrogen Bonding; Models, Molecular; Molecular Structure; Oxidation-Reduction; Protons; Ribonucleotide Reductases; Structure-Activity Relationship | 2004 |
Differences in recurrent COL7A1 mutations in dystrophic epidermolysis bullosa: ethnic-specific and worldwide recurrent mutations.
Topics: Alanine; Arginine; Asian People; Collagen Type VII; Cysteine; Epidermolysis Bullosa Dystrophica; Gene Deletion; Gene Frequency; Global Health; Glutamic Acid; Glycine; Humans; Japan; Mutation; Recurrence; United Kingdom | 2004 |
Level of glutathione is regulated by ATP-dependent ligation of glutamate and cysteine through photosynthesis in Arabidopsis thaliana: mechanism of strong interaction of light intensity with flowering.
Topics: Adenosine Triphosphate; Arabidopsis; Cysteine; Flowers; Gene Expression Regulation, Plant; Glutamate-Cysteine Ligase; Glutamic Acid; Glutathione; Light; Mutation; Photic Stimulation; Photosynthesis; Photosystem II Protein Complex; Plants, Genetically Modified; RNA, Messenger | 2004 |
The outer pore of the glutamate receptor channel has 2-fold rotational symmetry.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acid Motifs; Amino Acid Substitution; Animals; Binding Sites; Cadmium; Chelating Agents; Conserved Sequence; Copper; Cysteine; Dithiothreitol; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Space; Glutamic Acid; Ion Channel Gating; Kinetics; Ligands; Membrane Potentials; Microinjections; Models, Molecular; Oocytes; Patch-Clamp Techniques; Phenanthrolines; Protein Structure, Tertiary; Receptors, AMPA; Sulfhydryl Compounds; Unithiol; Xenopus | 2004 |
Activity-dependent regulation of dendritic synthesis and trafficking of AMPA receptors.
Topics: Action Potentials; Amino Acid Motifs; Animals; Arsenicals; Cells, Cultured; Cysteine; Dendrites; Excitatory Amino Acid Antagonists; Fetus; Glutamic Acid; Hippocampus; Neuronal Plasticity; Oxazines; Peptide Fragments; Protein Transport; Rats; Rats, Sprague-Dawley; Receptors, AMPA; RNA, Messenger; Synaptic Membranes; Synaptic Transmission; Up-Regulation | 2004 |
The ionic track in the F1-ATPase from the thermophilic Bacillus PS3.
Topics: Adenosine Diphosphate; Amino Acid Substitution; Arginine; Bacillus; Bacterial Proton-Translocating ATPases; Catalytic Domain; Copper; Cysteine; Enzyme Activation; Enzyme Inhibitors; Glutamic Acid; Lysine; Methylation; Mutagenesis, Site-Directed; Protein Subunits; Sodium-Potassium-Exchanging ATPase; Temperature | 2004 |
L-Glutamate in the extracellular space regulates endogenous D-aspartate homeostasis in rat pheochromocytoma MPT1 cells.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Cell Line, Tumor; Cysteine; Extracellular Space; Glutamic Acid; Homeostasis; Neurotransmitter Agents; PC12 Cells; Pheochromocytoma; Rats | 2004 |
Evidence for the proximity of the extreme N-terminus of the neurokinin-2 (NK2) tachykinin receptor to Cys167 in the putative fourth transmembrane helix.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Benzamides; Binding Sites; Binding, Competitive; CHO Cells; Cricetinae; Cysteine; Ethyl Methanesulfonate; Extracellular Space; Glutamic Acid; Humans; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Piperidines; Protein Structure, Secondary; Receptors, Neurokinin-2; Static Electricity; Sulfhydryl Reagents; Tritium | 2004 |
Spectroscopic and kinetic methods for ligand-protein interactions of glutamate receptor.
Topics: Chemistry Techniques, Analytical; Cysteine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Kinetics; Ligands; Protein Binding; Quinoxalines; Receptors, Glutamate; Spectroscopy, Fourier Transform Infrared | 2004 |
Chemistry and conformation of the ligand-binding domain of GluR2 subtype of glutamate receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Crystallography, X-Ray; Cysteine; Disulfides; Glutamic Acid; Humans; Hydrogen Bonding; Kainic Acid; Ligands; Molecular Conformation; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Receptors, Glutamate; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Water | 2004 |
Domain structures and roles in bacteriophage HK97 capsid assembly and maturation.
Topics: Asparagine; Aspartic Acid; Capsid; Coliphages; Crystallization; Cysteine; Glutamic Acid; Lysine; Protein Precursors; Protein Structure, Secondary; Protein Structure, Tertiary; Protein Subunits; Spectrum Analysis, Raman; Tryptophan; Tyrosine; Virus Assembly | 2004 |
Agonist-dependent and agonist-independent transactivations of the human constitutive androstane receptor are modulated by specific amino acid pairs.
Topics: Amino Acid Sequence; Animals; Binding Sites; Breast Neoplasms; Constitutive Androstane Receptor; Cysteine; Dimerization; Drug Stability; Glutamic Acid; Humans; Isoleucine; Leucine; Lysine; Mice; Models, Molecular; Molecular Sequence Data; Protein Structure, Secondary; Receptors, Calcitriol; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; Sequence Alignment; Signal Transduction; Structure-Activity Relationship; Transcription Factors; Transcriptional Activation; Transfection; Tumor Cells, Cultured | 2004 |
The importance of a critical protonation state and the fate of the catalytic steps in class A beta-lactamases and penicillin-binding proteins.
Topics: Amino Acid Motifs; Bacterial Proteins; beta-Lactamases; Binding Sites; Carrier Proteins; Catalysis; Cloning, Molecular; Cysteine; Escherichia coli; Genetic Vectors; Glutamic Acid; Hexosyltransferases; Hydrogen-Ion Concentration; Ions; Kinetics; Lysine; Magnetic Resonance Spectroscopy; Models, Chemical; Models, Molecular; Muramoylpentapeptide Carboxypeptidase; Mutation; Penicillin-Binding Proteins; Peptidyl Transferases; Protein Binding; Protons; Serine; Thermodynamics | 2004 |
The metal-free and calcium-bound structures of a gamma-carboxyglutamic acid-containing contryphan from Conus marmoreus, glacontryphan-M.
Topics: 1-Carboxyglutamic Acid; Animals; Calcium; Circular Dichroism; Cysteine; Disulfides; Glutamic Acid; Hydrogen-Ion Concentration; Ions; Magnetic Resonance Spectroscopy; Metals; Models, Molecular; Mollusk Venoms; Peptides; Peptides, Cyclic; Protein Conformation; Protein Processing, Post-Translational; Protein Structure, Tertiary; Protons; Snails | 2004 |
An electrostatically driven conformational transition is involved in the mechanisms of substrate binding and cooperativity in cytochrome P450eryF.
Topics: Allosteric Site; Amino Acid Substitution; Bacterial Proteins; Binding Sites; Cysteine; Cytochrome P-450 Enzyme System; Fluorescence Resonance Energy Transfer; Glutamic Acid; Heme; Mixed Function Oxygenases; Osmolar Concentration; Protein Conformation; Protein Structure, Secondary; Pyrenes; Static Electricity | 2004 |
Exogenous gamma-glutamyl cycle compounds supplemented to in vitro maturation medium influence in vitro fertilization, culture, and viability parameters of porcine oocytes and embryos.
Topics: Aminobutyrates; Animals; Cell Death; Culture Media; Culture Techniques; Cysteamine; Cysteine; Embryo, Mammalian; Female; Fertilization; Fertilization in Vitro; Glutamic Acid; Glutathione; Glycine; Male; Mercaptoethanol; Oocytes; Swine | 2004 |
Arabidopsis thaliana glutamate-cysteine ligase: functional properties, kinetic mechanism, and regulation of activity.
Topics: Adenosine Triphosphate; Arabidopsis; Binding Sites; Buthionine Sulfoximine; Chromatography, Gel; Cystamine; Cysteine; Dipeptides; Enzyme Inhibitors; Escherichia coli; Feedback, Physiological; Gene Expression; Glutamate-Cysteine Ligase; Glutamic Acid; Glutathione; Kinetics; Oxidation-Reduction; Oxidative Stress; Protein Conformation; Recombinant Proteins; Spectrometry, Mass, Electrospray Ionization | 2004 |
The distinct functional properties of the nucleotide-binding domain of ATP7B, the human copper-transporting ATPase: analysis of the Wilson disease mutations E1064A, H1069Q, R1151H, and C1104F.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Amino Acid Sequence; Arginine; Calorimetry; Cation Transport Proteins; Circular Dichroism; Copper-Transporting ATPases; Cysteine; Glutamic Acid; Histidine; Humans; Kinetics; Magnesium; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Nucleotides; Protein Binding; Protein Conformation; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Temperature | 2004 |
Crystal structure of a family 54 alpha-L-arabinofuranosidase reveals a novel carbohydrate-binding module that can bind arabinose.
Topics: Amino Acid Motifs; Amino Acid Sequence; Arabinose; Aspartic Acid; Aspergillus; Binding Sites; Carbohydrates; Catalytic Domain; Cloning, Molecular; Crystallography, X-Ray; Cysteine; Disulfides; DNA Mutational Analysis; Electrons; Glutamic Acid; Glycoside Hydrolases; Kinetics; Models, Molecular; Molecular Sequence Data; Multigene Family; Mutagenesis, Site-Directed; Protein Binding; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Sequence Homology, Amino Acid | 2004 |
The effect of sugar, amino acid, metal ion, and NaCl on model Maillard reaction under pH control.
Topics: Alanine; Amino Acids; Arabinose; Arginine; Aspartic Acid; Biochemistry; Carbohydrates; Colorimetry; Copper; Cysteine; Fructose; Glucose; Glutamic Acid; Glycine max; Hot Temperature; Hydrogen-Ion Concentration; Ions; Iron; Isoleucine; Leucine; Lysine; Maltose; Metals; Models, Chemical; Phenylalanine; Proline; Serine; Sodium Chloride; Temperature; Time Factors; Valine; Xylose | 2004 |
TM2 but not TM4 of subunit c'' interacts with TM7 of subunit a of the yeast V-ATPase as defined by disulfide-mediated cross-linking.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Arginine; Biological Transport; Cell Membrane; Cross-Linking Reagents; Cysteine; Disulfides; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Fungal Proteins; Fungi; Glutamic Acid; Hydrogen-Ion Concentration; Hydrolysis; Intracellular Membranes; Leucine; Lipids; Mutagenesis, Site-Directed; Mutation; Phenanthrolines; Phenotype; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Protons; Spectrophotometry; Vacuolar Proton-Translocating ATPases | 2004 |
Crystal structure of gamma-glutamylcysteine synthetase: insights into the mechanism of catalysis by a key enzyme for glutathione homeostasis.
Topics: Amino Acid Sequence; Binding Sites; Catalysis; Crystallography, X-Ray; Cysteine; Escherichia coli; Glutamate-Cysteine Ligase; Glutamic Acid; Glutathione; Homeostasis; Models, Molecular; Molecular Sequence Data; Protein Conformation; Recombinant Proteins; Sequence Homology, Amino Acid; Static Electricity | 2004 |
State-dependent changes in the electrostatic potential in the pore of a GluR channel.
Topics: Amino Acid Sequence; Animals; Cell Membrane; Cysteine; Glutamic Acid; Ion Channel Gating; Ions; Kinetics; Leucine; Membrane Potentials; Models, Molecular; Models, Statistical; Molecular Sequence Data; Mutagenesis; Mutation; Oocytes; Polyamines; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Receptors, Glutamate; RNA; RNA, Complementary; Static Electricity; Xenopus | 2005 |
Further studies on the fragmentation of protonated ions of peptides containing aspartic acid, glutamic acid, cysteine sulfinic acid, and cysteine sulfonic acid.
Topics: Amino Acid Sequence; Aspartic Acid; Cysteine; Glutamic Acid; Oligopeptides; Peptides; Spectrometry, Mass, Electrospray Ionization; Sulfonic Acids | 2005 |
Kinetic characteristics of native gamma-glutamylcysteine ligase in the aging housefly, Musca domestica L.
Topics: Adenosine Triphosphate; Aging; Animals; Buthionine Sulfoximine; Cysteine; Feedback, Physiological; Glutamate-Cysteine Ligase; Glutamic Acid; Glutathione; Houseflies; Kinetics | 2005 |
Mutation of glutamate 155 of the GABAA receptor beta2 subunit produces a spontaneously open channel: a trigger for channel activation.
Topics: Animals; Binding Sites; Biotin; Cysteine; GABA-A Receptor Agonists; Glutamic Acid; Ion Channel Gating; Kinetics; Ligands; Mutagenesis, Site-Directed; Mutation; Patch-Clamp Techniques; Pentobarbital; Protein Conformation; Rats; Receptors, GABA-A; Recombinant Proteins; Xenopus laevis | 2004 |
Energetics of proton transfer pathways in reaction centers from Rhodobacter sphaeroides. The Glu-H173 activated mutants.
Topics: Alanine; Cysteine; Cytoplasm; Electron Transport; Electrons; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Kinetics; Models, Chemical; Models, Molecular; Mutation; Nitrogen; Oxidation-Reduction; Oxygen; Protons; Rhodobacter sphaeroides; Software | 2005 |
Examination of lipid-bound conformation of apolipoprotein E4 by pyrene excimer fluorescence.
Topics: Apolipoprotein E4; Apolipoproteins E; Arginine; Cross-Linking Reagents; Cysteine; Electrophoresis, Polyacrylamide Gel; Fluorescence Resonance Energy Transfer; Glutamic Acid; Humans; Lipids; Lipoproteins; Models, Molecular; Mutagenesis, Site-Directed; Protein Binding; Protein Conformation; Protein Isoforms; Protein Structure, Tertiary; Pyrenes; Risk Factors; Spectrometry, Fluorescence | 2005 |
Small-scale molecular motions accomplish glutamate uptake in human glutamate transporters.
Topics: Amino Acid Transport System X-AG; Animals; Anisotropy; Cysteine; Female; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Humans; Maleimides; Models, Chemical; Models, Molecular; Motion; Mutagenesis, Site-Directed; Oocytes; Patch-Clamp Techniques; Protein Conformation; Protein Structure, Tertiary; Protein Subunits; Recombinant Fusion Proteins; Rhodamines; Structure-Activity Relationship; Symporters; Xenopus laevis | 2005 |
The conserved histidine 295 does not contribute to proton cotransport by the glutamate transporter EAAC1.
Topics: Amino Acid Substitution; Amino Acid Transport System X-AG; Animals; Biological Transport, Active; Cell Line; Conserved Sequence; Cysteine; Excitatory Amino Acid Transporter 3; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Glutamine; Histidine; Humans; Hydrogen-Ion Concentration; Kinetics; Lysine; Models, Chemical; Patch-Clamp Techniques; Protons; Rats; Symporters; Transfection | 2005 |
T-786C polymorphism of the endothelial nitric oxide synthase gene is associated with albuminuria in the diabetes heart study.
Topics: Aged; Albuminuria; Aspartic Acid; Creatinine; Cysteine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Exons; Female; Genetic Predisposition to Disease; Genotype; Glutamic Acid; Homozygote; Humans; Linkage Disequilibrium; Male; Middle Aged; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Odds Ratio; Polymorphism, Genetic; Promoter Regions, Genetic; Threonine | 2005 |
Site-directed mutagenesis of active site residues of phosphite dehydrogenase.
Topics: Amino Acid Sequence; Arginine; Bacterial Proteins; Binding Sites; Cysteine; Deuterium Exchange Measurement; Diethyl Pyrocarbonate; Glutamic Acid; Glutamine; Histidine; Hydrogen-Ion Concentration; Kinetics; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; NADH, NADPH Oxidoreductases; Phosphites; Sequence Alignment | 2005 |
Identification of amino acids required for the functional up-regulation of human dihydrofolate reductase protein in response to antifolate Treatment.
Topics: Amino Acids; Animals; Binding Sites; Blotting, Western; Catalysis; Cell Survival; CHO Cells; Cloning, Molecular; Cricetinae; Cysteine; DNA Primers; Folic Acid Antagonists; Gene Expression Regulation, Enzymologic; Glutamic Acid; Glutathione Transferase; Green Fluorescent Proteins; Humans; Inhibitory Concentration 50; Kinetics; Leucine; Methotrexate; Microscopy, Fluorescence; Models, Biological; Mutagenesis, Site-Directed; Mutation; NADP; Protein Biosynthesis; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serine; Spectrophotometry; Tetrahydrofolate Dehydrogenase; Time Factors; Transcription, Genetic; Transfection; Up-Regulation | 2005 |
Transport of L-[14C]cystine and L-[14C]cysteine by subtypes of high affinity glutamate transporters over-expressed in HEK cells.
Topics: Amino Acid Transport System X-AG; Biological Transport, Active; Carbon Radioisotopes; Carrier Proteins; Cell Line; Cell Membrane; Cysteine; Cystine; Dipeptides; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; Extracellular Fluid; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Glutathione; Homocysteine; Humans; Kinetics; Oxidation-Reduction; Symporters | 2005 |
Point mutations at the type I Cu ligands, Cys457 and Met467, and at the putative proton donor, Asp105, in Myrothecium verrucaria bilirubin oxidase and reactions with dioxygen.
Topics: Alanine; Amino Acid Substitution; Asparagine; Aspartic Acid; Copper; Cysteine; Dithionite; Fungal Proteins; Glutamic Acid; Glutamine; Hypocreales; Ligands; Methionine; Oxidation-Reduction; Oxidoreductases Acting on CH-CH Group Donors; Oxygen; Point Mutation; Protons; Serine | 2005 |
Differential desensitization of homozygous haplotypes of the beta2-adrenergic receptor in lymphocytes.
Topics: Adult; Arginine; Cyclic AMP; Cysteine; Cytokines; Desensitization, Immunologic; Down-Regulation; Female; Glutamic Acid; Glutamine; Glycine; Haplotypes; Homozygote; Humans; Lymphocytes; Male; Middle Aged; Polymorphism, Single Nucleotide; Receptors, Adrenergic, beta-2; Signal Transduction; T-Lymphocytes, Helper-Inducer | 2005 |
Site-directed disulfide mapping of residues contributing to the Ca2+ and K+ binding pocket of the NCKX2 Na+/Ca2+-K+ exchanger.
Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Calcium; Cell Line; Cell Membrane; Cross-Linking Reagents; Cysteine; Disulfides; Glutamic Acid; Humans; Hydrolysis; Hydrophobic and Hydrophilic Interactions; Molecular Sequence Data; Mutagenesis, Insertional; Peptide Mapping; Phenanthrolines; Potassium; Protein Sorting Signals; Protein Structure, Secondary; Repetitive Sequences, Amino Acid; Serine; Sodium-Calcium Exchanger | 2005 |
Protective effect of serofendic acid on glutamate-induced neurotoxicity in rat cultured motor neurons.
Topics: Animals; Cell Survival; Cells, Cultured; Cysteine; Dicarboxylic Acids; Diterpenes; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Embryo, Mammalian; Glutamic Acid; Motor Neurons; Neuroprotective Agents; Neurotransmitter Uptake Inhibitors; Nitric Oxide Donors; Pyrrolidines; Rats; S-Nitrosothiols; Spinal Cord; Time Factors | 2005 |
Functional metabotropic glutamate receptors on nuclei from brain and primary cultured striatal neurons. Role of transporters in delivering ligand.
Topics: Biological Transport; Calcium; Cell Membrane; Cell Nucleus; Coloring Agents; Cysteine; Cytoplasm; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Inhibitors; Glutamic Acid; Glycine; Immunohistochemistry; Ligands; Light; Microscopy, Fluorescence; Models, Biological; Neurons; Phosphorylation; Propionates; Protein Binding; Receptors, Metabotropic Glutamate; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Sodium; Subcellular Fractions; Thiophenes; Time Factors | 2005 |
A helical hairpin region of soluble annexin B12 refolds and forms a continuous transmembrane helix at mildly acidic pH.
Topics: Annexins; Aspartic Acid; Binding Sites; Calcium; Crystallography, X-Ray; Cysteine; Electron Spin Resonance Spectroscopy; Escherichia coli; Glutamic Acid; Humans; Hydrogen-Ion Concentration; Lipid Bilayers; Models, Molecular; Mutation; Nitric Oxide; Protein Conformation; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Spin Labels; Thermodynamics | 2005 |
Formation of an antiparallel, intermolecular coiled coil is associated with in vivo dimerization of osmosensor and osmoprotectant transporter ProP in Escherichia coli.
Topics: Amino Acid Sequence; Amino Acid Substitution; Arginine; Cross-Linking Reagents; Cysteine; Dimerization; Escherichia coli; Escherichia coli Proteins; Ethylmaleimide; Glutamic Acid; Isoleucine; Molecular Sequence Data; Mutagenesis, Site-Directed; Osmolar Concentration; Osmotic Pressure; Oxidation-Reduction; Peptide Fragments; Protein Structure, Secondary; Symporters | 2005 |
Exploring the binding domain of EmrE, the smallest multidrug transporter.
Topics: Antiporters; Binding Sites; Cell Membrane; Cysteine; Dimerization; Dose-Response Relationship, Drug; Drug Resistance, Multiple, Bacterial; Escherichia coli; Escherichia coli Proteins; Fluoresceins; Fluorescent Dyes; Glutamic Acid; Hydrogen-Ion Concentration; Indicators and Reagents; Membrane Proteins; Membrane Transport Proteins; Mesylates; Mutagenesis, Site-Directed; Onium Compounds; Organophosphorus Compounds; Plasmids; Protein Binding; Protein Structure, Tertiary; Protons; Substrate Specificity | 2005 |
Endothelial NO synthase polymorphisms and postural tachycardia syndrome.
Topics: Adolescent; Adult; Alleles; Aspartic Acid; Case-Control Studies; Cysteine; Female; Genotype; Glutamic Acid; Heart Rate; Homozygote; Humans; Male; Middle Aged; Nitric Oxide Synthase Type III; Norepinephrine; Polymorphism, Genetic; Posture; Severity of Illness Index; Syndrome; Tachycardia; Threonine | 2005 |
Why is the Arg5-Glu13 salt bridge conserved in mammalian alpha-defensins?
Topics: Alleles; alpha-Defensins; Amino Acid Sequence; Animals; Arginine; Chromatography, High Pressure Liquid; Conserved Sequence; Cysteine; Disulfides; Dose-Response Relationship, Drug; Escherichia coli; Glutamic Acid; Glycine; Humans; Mice; Models, Molecular; Molecular Sequence Data; Neutrophils; Oxygen; Pancreatic Elastase; Peptides; Protein Folding; Salts; Sequence Homology, Amino Acid; Sodium Chloride; Staphylococcus aureus; Time Factors | 2005 |
Linker chains of the gigantic hemoglobin of the earthworm Lumbricus terrestris: primary structures of linkers L2, L3, and L4 and analysis of the connectivity of the disulfide bonds in linker L1.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Base Sequence; Binding Sites; Calcium; Chromatography, High Pressure Liquid; Cysteine; Disulfides; Dithiothreitol; DNA, Complementary; Glutamic Acid; Heme; Hemoglobins; Histidine; Humans; Ligands; Mass Spectrometry; Models, Molecular; Molecular Sequence Data; Oligochaeta; Protein Binding; Protein Processing, Post-Translational; Protein Structure, Tertiary; Receptors, LDL; RNA, Messenger; Sequence Homology, Amino Acid; Sodium Dodecyl Sulfate; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Superoxide Dismutase | 2006 |
Fragmentation of the deprotonated ions of peptides containing cysteine, cysteine sulfinic acid, cysteine sulfonic acid, aspartic acid, and glutamic acid.
Topics: Amino Acid Sequence; Aspartic Acid; Cysteine; Glutamic Acid; Molecular Sequence Data; Peptides; Spectrometry, Mass, Electrospray Ionization; Sulfonic Acids | 2006 |
Immunocytochemical localization of glutathione precursors in plant cells.
Topics: Cucurbita; Cysteine; Glutamic Acid; Glutathione; Glycine; Immunohistochemistry; Microscopy, Electron, Transmission | 2006 |
Prospective study of FGFR3 mutations as a prognostic factor in nonmuscle invasive urothelial bladder carcinomas.
Topics: Adult; Aged; Aged, 80 and over; Alanine; Cysteine; Female; Glutamic Acid; Glycine; Humans; Leucine; Male; Middle Aged; Multivariate Analysis; Mutation; Phenylalanine; Polymerase Chain Reaction; Predictive Value of Tests; Prognosis; Proportional Hazards Models; Prospective Studies; Receptor, Fibroblast Growth Factor, Type 3; Sequence Analysis, DNA; Serine; Tyrosine; Urinary Bladder Neoplasms | 2006 |
Determination of d-serine and related neuroactive amino acids in human plasma by high-performance liquid chromatography with fluorimetric detection.
Topics: Amino Acids; Chromatography, High Pressure Liquid; Cysteine; Fluorometry; Glutamic Acid; Glutamine; Humans; Molecular Structure; o-Phthalaldehyde; Serine; Stereoisomerism | 2006 |
Copper binding to the N-terminal metal-binding sites or the CPC motif is not essential for copper-induced trafficking of the human Wilson protein (ATP7B).
Topics: Adenosine Triphosphatases; Amino Acid Sequence; Binding Sites; Cation Transport Proteins; Copper; Copper-Transporting ATPases; Cysteine; DNA Primers; Glutamic Acid; Glycine; Hepatolenticular Degeneration; Humans; Models, Molecular; Oligopeptides; Polymerase Chain Reaction; Protein Conformation; Threonine | 2007 |
Neuroprotective effects of galanthamine and tacrine against glutamate neurotoxicity.
Topics: Animals; Cell Survival; Cells, Cultured; Cerebral Cortex; Cholinesterase Inhibitors; Cysteine; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Fetus; Galantamine; Glutamic Acid; Ionomycin; Ionophores; Mecamylamine; Neuroprotective Agents; Nicotinic Antagonists; Nitric Oxide Donors; Rats; Rats, Wistar; S-Nitrosothiols; Tacrine | 2006 |
Measurement of conformational changes accompanying desensitization in an ionotropic glutamate receptor.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Line; Crystallography, X-Ray; Cysteine; Dimerization; Disulfides; Electrophysiology; Glutamic Acid; Humans; Mesylates; Models, Molecular; Molecular Sequence Data; Oocytes; Point Mutation; Protein Structure, Quaternary; Rats; Receptors, AMPA; Sulfhydryl Reagents; Xenopus laevis | 2006 |
Crystal structures of E. coli CcmG and its mutants reveal key roles of the N-terminal beta-sheet and the fingerprint region.
Topics: Amino Acid Sequence; Binding Sites; Circular Dichroism; Crystallography, X-Ray; Cysteine; Escherichia coli; Escherichia coli Proteins; Glutamic Acid; Models, Molecular; Molecular Sequence Data; Oxidation-Reduction; Protein Conformation; Protein Disulfide Reductase (Glutathione); Protein Folding; Sequence Alignment; Structure-Activity Relationship; Tyrosine | 2006 |
Toll-like receptor 4 region Glu24-Lys47 is a site for MD-2 binding: importance of CYS29 and CYS40.
Topics: Amino Acid Sequence; Binding Sites; Cell Line; Cysteine; Glutamic Acid; Humans; Lymphocyte Antigen 96; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; NF-kappa B; Signal Transduction; Toll-Like Receptor 4 | 2006 |
Characterization of the amino acids from Neisseria meningitidis MsrA involved in the chemical catalysis of the methionine sulfoxide reduction step.
Topics: Cysteine; Glutamic Acid; Hydrogen-Ion Concentration; Kinetics; Methionine; Methionine Sulfoxide Reductases; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Neisseria meningitidis; Oxidative Stress; Oxidoreductases; Sulfhydryl Compounds; Sulfoxides; Tyrosine | 2006 |
Virus-induced changes in the subcellular distribution of glutathione precursors in Cucurbita pepo (L.).
Topics: Cucurbita; Cysteine; Glutamic Acid; Glutathione; Glycine; Immunochemistry; Microscopy, Electron, Transmission; Plant Leaves; Plant Viruses | 2007 |
Block of kainate receptor desensitization uncovers a key trafficking checkpoint.
Topics: Animals; Cells, Cultured; Cysteine; Enzyme-Linked Immunosorbent Assay; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GluK2 Kainate Receptor; Glutamic Acid; Green Fluorescent Proteins; Hippocampus; Humans; Kainic Acid; Membrane Potentials; Models, Biological; Mutation; Neurons; Oocytes; Patch-Clamp Techniques; Protein Structure, Tertiary; Protein Transport; Quinoxalines; Receptors, AMPA; Receptors, Kainic Acid; Structure-Activity Relationship; Transfection; Xenopus | 2006 |
Metabolism of glutathione in tumour cells as evidenced by 1H MRS.
Topics: Buthionine Sulfoximine; Cell Line, Tumor; Cysteine; Glutamic Acid; Glutathione; Humans; Magnetic Resonance Spectroscopy; Neoplasms; Protons; Time Factors | 2007 |
The carboxylate shift in zinc enzymes: a computational study.
Topics: Aspartic Acid; Carboxylic Acids; Catalytic Domain; Computational Biology; Crystallography, X-Ray; Cysteine; Electron Transport; Enzymes; Glutamic Acid; Histidine; Ligands; Metalloproteins; Oxygen; Protein Conformation; Zinc | 2007 |
Crystal structure of Helicobacter pylori formamidase AmiF reveals a cysteine-glutamate-lysine catalytic triad.
Topics: Amidohydrolases; Amino Acid Sequence; Binding Sites; Catalysis; Crystallography, X-Ray; Cysteine; Glutamic Acid; Helicobacter pylori; Ligands; Lysine; Models, Molecular; Molecular Sequence Data; Mutation; Protein Conformation; Sequence Homology, Amino Acid | 2007 |
Catalytic mechanism of Zn2+-dependent polyol dehydrogenases: kinetic comparison of sheep liver sorbitol dehydrogenase with wild-type and Glu154-->Cys forms of yeast xylitol dehydrogenase.
Topics: Animals; Cysteine; D-Xylulose Reductase; Deuterium; Enzyme Inhibitors; Fungal Proteins; Glutamic Acid; Humans; Hydrogen-Ion Concentration; L-Iditol 2-Dehydrogenase; Liver; Molecular Structure; NAD; Oxidation-Reduction; Point Mutation; Sheep; Solvents; Sorbitol; Zinc | 2007 |
Chiral crystallization of glutamic acid on self assembled films of cysteine.
Topics: Crystallization; Cysteine; Electrodes; Glutamic Acid; Gold; Microscopy, Electron, Scanning; Nanoparticles; Nanotechnology; Powder Diffraction; Stereoisomerism; Surface Properties | 2007 |
Electronic structure of the PYP chromophore in its native protein environment.
Topics: Amino Acid Sequence; Arginine; Bacterial Proteins; Cysteine; Glutamic Acid; Models, Molecular; Phenylalanine; Photoreceptors, Microbial; Threonine; Tyrosine; Valine | 2007 |
Subunit-specific contribution of pore-forming domains to NMDA receptor channel structure and gating.
Topics: Amino Acid Sequence; Animals; Cysteine; Glutamic Acid; Glycine; Humans; Ion Channel Gating; Membrane Potentials; Microinjections; Models, Biological; Models, Molecular; Molecular Sequence Data; Mutation; Oocytes; Protein Conformation; Protein Structure, Tertiary; Protein Subunits; Receptors, N-Methyl-D-Aspartate; Xenopus laevis | 2007 |
The protease domain of procollagen C-proteinase (BMP1) lacks substrate selectivity, which is conferred by non-proteolytic domains.
Topics: Amino Acid Motifs; Animals; Bone Morphogenetic Protein 1; Bone Morphogenetic Proteins; Cell Line; Collagen Type VII; Cysteine; Disulfides; DNA, Complementary; Drosophila melanogaster; Escherichia coli; Gene Expression; Glutamic Acid; Humans; Inclusion Bodies; Mass Spectrometry; Metalloendopeptidases; Mutation; Protein Folding; Protein Structure, Tertiary; Recombinant Proteins; Substrate Specificity | 2007 |
Aspartate-444 is essential for productive substrate interactions in a neuronal glutamate transporter.
Topics: Alanine; Animals; Aspartic Acid; Binding Sites; Cysteine; Dicarboxylic Acid Transporters; Excitatory Amino Acid Transporter 3; Glutamic Acid; HeLa Cells; Humans; Microinjections; Mutation; Neurons; Oocytes; Protein Conformation; Protein Structure, Tertiary; Rabbits; Serine; Succinic Acid; Transfection; Xenopus laevis | 2007 |
Active-site properties of the oxidized and reduced C-terminal domain of DsbD obtained by NMR spectroscopy.
Topics: Amino Acid Motifs; Aspartic Acid; Binding Sites; Cysteine; Escherichia coli; Escherichia coli Proteins; Glutamic Acid; Hydrogen-Ion Concentration; Models, Molecular; Mutation; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Oxidoreductases; Protein Structure, Tertiary | 2007 |
Assessing the role of the active-site cysteine ligand in the superoxide reductase from Desulfoarculus baarsii.
Topics: Amino Acid Substitution; Bacterial Proteins; Base Sequence; Binding Sites; Cysteine; Desulfovibrio; Glutamic Acid; Hydrogen Peroxide; Hydrogen-Ion Concentration; Molecular Sequence Data; Mutagenesis, Site-Directed; Oxidoreductases; Polymorphism, Single Nucleotide; Recombinant Proteins | 2007 |
Docking of the periplasmic FecB binding protein to the FecCD transmembrane proteins in the ferric citrate transport system of Escherichia coli.
Topics: Alanine; Amino Acid Sequence; Arginine; ATP-Binding Cassette Transporters; Biological Transport; Cysteine; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Escherichia coli Proteins; Ferric Compounds; Gene Expression Regulation, Bacterial; Glutamic Acid; Hydrogen Bonding; Ion Pumps; Membrane Proteins; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Polymerase Chain Reaction; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Structure-Activity Relationship | 2007 |
Evidence that the p38 MAP kinase pathway is dysregulated in HLA-B27-expressing human monocytic cells: correlation with HLA-B27 misfolding.
Topics: Cell Line; Cysteine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutamic Acid; HLA-B27 Antigen; Humans; Monocytes; p38 Mitogen-Activated Protein Kinases; Protein Conformation; Protein Folding; RNA, Small Interfering; Salmonella enteritidis; Salmonella Infections; Transfection | 2007 |
Identification of the cysteine residue exposed by the conformational change in pig heart succinyl-CoA:3-ketoacid coenzyme A transferase on binding coenzyme A.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Binding Sites; Coenzyme A; Coenzyme A-Transferases; Crystallography, X-Ray; Cysteine; Escherichia coli; Escherichia coli Proteins; Glutamic Acid; Models, Chemical; Models, Molecular; Myocardium; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Serine; Swine | 2007 |
The cystine/cysteine cycle: a redox cycle regulating susceptibility versus resistance to cell death.
Topics: Amino Acid Transport System y+; Animals; Antimetabolites, Antineoplastic; Apoptosis; Blotting, Northern; Buthionine Sulfoximine; Caspases; Cell Survival; Cysteine; Cystine; Fluorescent Antibody Technique; Glutamic Acid; Glutathione; Humans; Hydrogen Peroxide; Immunoblotting; Lipid Peroxidation; Membrane Potential, Mitochondrial; Mice; Oxidants; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species | 2008 |
The cys-loop ligand-gated ion channel gene superfamily of the red flour beetle, Tribolium castaneum.
Topics: Amino Acid Sequence; Animals; Cysteine; Glutamic Acid; Histidine; Ion Channel Gating; Ion Channels; Molecular Sequence Data; Receptors, Nicotinic; Reverse Transcriptase Polymerase Chain Reaction; Sequence Homology, Amino Acid; Tribolium | 2007 |
Nitrated alpha-synuclein and microglial neuroregulatory activities.
Topics: alpha-Synuclein; Animals; Cathepsin B; Cells, Cultured; Cystatins; Cysteine; Cytoskeletal Proteins; Dopamine; Gene Expression Regulation; Glutamic Acid; Glutathione; Mice; Mice, Inbred C57BL; Microglia; Nerve Tissue Proteins; NF-kappa B; Nitrates; Oxidation-Reduction; Oxidative Stress; Parkinson Disease; Protein Array Analysis; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tandem Mass Spectrometry | 2008 |
The M1P1 loop of TASK3 K2P channels apposes the selectivity filter and influences channel function.
Topics: Cysteine; Electrophysiology; Gene Expression Regulation; Glutamic Acid; Histidine; Humans; Hydrogen-Ion Concentration; Kinetics; Mutagenesis, Site-Directed; Mutation; Patch-Clamp Techniques; Point Mutation; Potassium Channels, Tandem Pore Domain; Protein Structure, Tertiary; Zinc | 2008 |
Cysteine pKa depression by a protonated glutamic acid in human DJ-1.
Topics: Crystallization; Cysteine; Databases, Genetic; Glutamic Acid; Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Intracellular Signaling Peptides and Proteins; Models, Molecular; Oncogene Proteins; Oxidative Stress; Parkinson Disease; Protein Conformation; Protein Deglycase DJ-1; Recombinant Proteins; X-Ray Diffraction | 2008 |
Control of the coordination structure of organometallic palladium complexes in an apo-ferritin cage.
Topics: Apoferritins; Binding Sites; Crystallography, X-Ray; Cysteine; Glutamic Acid; Histidine; Mutation; Organometallic Compounds; Palladium | 2008 |
A novel approach to enhancing cellular glutathione levels.
Topics: Animals; Antioxidants; Biological Transport; Catechin; Chromatography, High Pressure Liquid; Cysteamine; Cysteine; Cystine; Glutamic Acid; Glutathione; Neurons; Oxidative Stress; Rats | 2008 |
Identification of four novel types of in vitro protein modifications.
Topics: Algorithms; Amino Acid Sequence; Animals; Aspartic Acid; Cattle; Chromatography, High Pressure Liquid; Cysteine; Glutamic Acid; Glycerol; Lysine; Mass Spectrometry; Molecular Sequence Data; Molecular Structure; Protein Processing, Post-Translational; Proteins; Reproducibility of Results; Sequence Alignment; Serum Albumin, Bovine | 2008 |
Elevated glutathione production by adding precursor amino acids coupled with ATP in high cell density cultivation of Candida utilis.
Topics: Adenosine Triphosphate; Amino Acids; Candida; Cell Count; Culture Media; Cysteine; Fermentation; Glutamic Acid; Glutathione; Glycine | 2008 |
Structural basis of NR2B-selective antagonist recognition by N-methyl-D-aspartate receptors.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Cysteine; DNA, Complementary; Dose-Response Relationship, Drug; Electrophysiology; Female; Glutamic Acid; Glycine; Hydrogen-Ion Concentration; Inhibitory Concentration 50; Mice; Microinjections; Models, Molecular; Molecular Conformation; Molecular Sequence Data; Oocytes; Patch-Clamp Techniques; Piperidines; Plasmids; Protein Structure, Secondary; Protein Structure, Tertiary; Rats; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins; Reference Standards; Sequence Homology, Amino Acid; Temperature; Xenopus laevis; Zinc | 2009 |
Structural elucidation of the Cys-His-Glu-Asn proteolytic relay in the secreted CHAP domain enzyme from the human pathogen Staphylococcus saprophyticus.
Topics: Asparagine; Bacterial Proteins; Catalytic Domain; Cysteine; Endopeptidases; Glutamic Acid; Histidine; Magnetic Resonance Spectroscopy; Protein Structure, Tertiary; Staphylococcus | 2009 |
Regions of the amino terminus of the P2X receptor required for modification by phorbol ester and mGluR1alpha receptors.
Topics: Adenosine Triphosphate; Animals; Cysteine; Electric Stimulation; Enzyme Inhibitors; Glutamic Acid; Humans; Membrane Potentials; Mutagenesis; Oocytes; Patch-Clamp Techniques; Peptide Fragments; Phorbol Esters; Receptors, Metabotropic Glutamate; Receptors, Purinergic P2; Receptors, Purinergic P2X2; Xenopus laevis | 2009 |
Formation of a stabilized cysteine sulfinic acid is critical for the mitochondrial function of the parkinsonism protein DJ-1.
Topics: Amino Acid Substitution; Animals; Cell Line, Tumor; Cysteine; Genetic Diseases, Inborn; Glutamic Acid; Humans; Intracellular Signaling Peptides and Proteins; Mice; Mitochondrial Proteins; Mutation; Oncogene Proteins; Oxidation-Reduction; Parkinson Disease; Protein Deglycase DJ-1; Sulfinic Acids | 2009 |
Intracellular proton-transfer mutants in a CLC Cl-/H+ exchanger.
Topics: Amino Acid Sequence; Amino Acid Substitution; Antiporters; Binding Sites; Chloride Channels; Chlorides; Cysteine; Cytoplasm; Energy Transfer; Escherichia coli Proteins; Glutamic Acid; Hydrogen-Ion Concentration; Ion Transport; Kinetics; Mutant Proteins; Protein Conformation; Protons; Static Electricity; Structure-Activity Relationship; Thermodynamics | 2009 |
Glutamate receptors on myelinated spinal cord axons: I. GluR6 kainate receptors.
Topics: Animals; Axons; Calcium; Calcium Channels, L-Type; Cysteine; Egtazic Acid; Excitatory Amino Acid Antagonists; GluK2 Kainate Receptor; Glutamic Acid; Hydroxocobalamin; Male; Microscopy, Confocal; Myoglobin; Nerve Fibers, Myelinated; Nitric Oxide; PDZ Domains; Peptides; Protein Multimerization; Rats; Rats, Long-Evans; Receptors, Kainic Acid; Ryanodine; Spinal Cord Injuries; Spinal Nerve Roots | 2009 |
Gas-phase IR spectroscopy of deprotonated amino acids.
Topics: Amino Acids; Anions; Aspartic Acid; Cysteine; Gases; Glutamic Acid; Phenylalanine; Protons; Serine; Spectrophotometry; Spectrophotometry, Infrared; Tyrosine | 2009 |
Structural adaptability of zinc binding sites: different structures in partially, fully, and heavy-metal loaded states.
Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Cysteine; Glutamic Acid; Histidine; Metalloproteins; Molecular Sequence Data; Molecular Structure; Zinc; Zinc Fingers | 2009 |
Novel plasma phospholipid biomarkers of autism: mitochondrial dysfunction as a putative causative mechanism.
Topics: Adolescent; Astrocytes; Autistic Disorder; Biomarkers; Child; Child, Preschool; Cysteine; Fatty Acids; Female; Glutamic Acid; Glutathione; Hepatocytes; Humans; Male; Methionine; Mitochondria; Neurons; Phospholipids; Siblings | 2009 |
Mutagenesis and cysteine scanning of transmembrane domain 10 of the human dipeptide transporter.
Topics: Amino Acid Substitution; Cell Line; Cell Membrane; Cysteine; Dipeptides; Extracellular Space; Glutamic Acid; Glycine; Humans; Mutagenesis, Site-Directed; Peptide Transporter 1; Protein Structure, Tertiary; Protein Transport; Symporters; Tyrosine | 2009 |
Pharmacological characterization of glutamate Na+-independent transport in retinal cell cultures: implications in the glutathione metabolism.
Topics: Amino Acid Transport System y+; Animals; Cells, Cultured; Chick Embryo; Cysteine; Glutamic Acid; Glutathione; Neurons; Oxidation-Reduction; Oxidative Stress; Retina; Sodium | 2010 |
Volatile anesthetics attenuate oxidative stress-reduced activity of glutamate transporter type 3.
Topics: Anesthetics, Inhalation; Animals; Cysteine; Desflurane; Dose-Response Relationship, Drug; Excitatory Amino Acid Transporter 3; Female; Glutamic Acid; Isoflurane; Kinetics; Membrane Potentials; Methyl Ethers; Neuroprotective Agents; Oxidative Stress; Rats; Sevoflurane; tert-Butylhydroperoxide; Xenopus laevis | 2009 |
X-ray absorption studies of Zn(2+)-binding sites in Escherichia coli transhydrogenase and its betaH91K mutant.
Topics: Amino Acid Substitution; Aspartic Acid; Binding Sites; Cysteine; Escherichia coli Proteins; Glutamic Acid; Histidine; Models, Molecular; Mutation; NADP Transhydrogenases; Protein Binding; Protein Structure, Tertiary; Spectrometry, X-Ray Emission; Zinc | 2010 |
A futile cycle, formed between two ATP-dependant gamma-glutamyl cycle enzymes, gamma-glutamyl cysteine synthetase and 5-oxoprolinase: the cause of cellular ATP depletion in nephrotic cystinosis?
Topics: Adenosine Triphosphate; Amino Acid Transport Systems, Neutral; Animals; Cysteine; Cystinosis; Disease Models, Animal; Glutamate-Cysteine Ligase; Glutamic Acid; Humans; Mice; Models, Biological; Pyroglutamate Hydrolase; Pyrrolidonecarboxylic Acid | 2010 |
Basis for the specificity and activation of the serpin protein Z-dependent proteinase inhibitor (ZPI) as an inhibitor of membrane-associated factor Xa.
Topics: Binding Sites; Blood Proteins; Calcium; Cell Membrane; Crystallography, X-Ray; Cysteine; Factor Xa; Glutamic Acid; Humans; Kinetics; Light; Models, Molecular; Mutation; Phospholipids; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Scattering, Radiation; Serpins; Tyrosine | 2010 |
Redox regulation of Plasmodium falciparum ornithine δ-aminotransferase.
Topics: Amino Acid Substitution; Binding Sites; Crystallography, X-Ray; Cysteine; Enzyme Activators; Glutamic Acid; Kinetics; Metabolic Networks and Pathways; Models, Biological; Models, Molecular; Mutagenesis, Site-Directed; Ornithine; Ornithine-Oxo-Acid Transaminase; Oxidation-Reduction; Plasmodium falciparum; Protein Structure, Tertiary; Protozoan Proteins; Thioredoxins | 2010 |
Palmitoylation and function of glial glutamate transporter-1 is reduced in the YAC128 mouse model of Huntington disease.
Topics: Animals; Cell Line; Chlorocebus aethiops; COS Cells; Cysteine; Disease Models, Animal; Down-Regulation; Excitatory Amino Acid Transporter 2; Glutamic Acid; Huntington Disease; Lipoylation; Mice; Mice, Transgenic; Mutagenesis, Site-Directed; Neuroglia; Rats | 2010 |
Comparative evaluation of glutamate-sensitive radiopharmaceuticals: Technetium-99m-glutamic acid and technetium-99m-diethylenetriaminepentaacetic acid-bis(glutamate) conjugate for tumor imaging.
Topics: Animal Structures; Animals; Carcinoma, Ehrlich Tumor; Cell Line, Tumor; Cell Survival; Cysteine; Drug Stability; Glutamic Acid; Humans; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred BALB C; Molecular Structure; Neoplasms; Pentetic Acid; Rabbits; Radiopharmaceuticals; Technetium; Tissue Distribution; Tomography, Emission-Computed, Single-Photon; Whole Body Imaging | 2010 |
Effect of genetic characteristics and environmental factors on organosulfur compounds in garlic ( Allium sativum L.) grown in Andalusia, Spain.
Topics: Cysteine; Environment; Garlic; Genotype; Glutamic Acid; Plant Roots; Spain; Species Specificity; Sulfur Compounds | 2011 |
Use of a HEHEHE purification tag instead of a hexahistidine tag improves biodistribution of affibody molecules site-specifically labeled with (99m)Tc, (111)In, and (125)I.
Topics: Animals; Cell Line; Cell Line, Tumor; Cysteine; Female; Glutamic Acid; Histidine; Indium Radioisotopes; Iron Radioisotopes; Liver; Mice; Oligopeptides; Organotechnetium Compounds; Radioisotopes; Receptor, ErbB-2; Recombinant Fusion Proteins; Tissue Distribution | 2011 |
Design, modeling, expression, and chemoselective PEGylation of a new nanosize cysteine analog of erythropoietin.
Topics: Animals; Cell Line; Cell Proliferation; CHO Cells; Chromatography, Gel; Cloning, Molecular; Computer Simulation; Cricetinae; Cricetulus; Cysteine; Drug Delivery Systems; Erythropoietin; Glutamic Acid; Humans; Methotrexate; Molecular Dynamics Simulation; Mutagenesis, Site-Directed; Nanoparticles; Polyethylene Glycols; Protein Binding; Protein Stability; Recombinant Proteins; Spectroscopy, Fourier Transform Infrared | 2011 |
Arrangement of subunits in functional NMDA receptors.
Topics: 4-Aminopyridine; Amino Acid Motifs; Analysis of Variance; Animals; Cell Line, Transformed; Copper Sulfate; Cysteine; Electric Stimulation; Excitatory Amino Acid Agents; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Humans; Kynurenic Acid; Membrane Potentials; Microinjections; Models, Molecular; Mutagenesis; Mutation; Oocytes; Patch-Clamp Techniques; Protein Structure, Tertiary; Protein Subunits; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Statistics, Nonparametric; Transfection; Xenopus | 2011 |
Sulfur amino acid-free diet results in increased glutamate in human midbrain: a pilot magnetic resonance spectroscopic study.
Topics: Adolescent; Adult; Amino Acids, Sulfur; Cysteine; Diet; Female; Glutamic Acid; Glutathione; Humans; Magnetic Resonance Imaging; Male; Malnutrition; Mesencephalon; Methionine; Multivariate Analysis; Nutrition Assessment; Parietal Lobe; Pilot Projects; Regression Analysis; Young Adult | 2012 |
Subcellular distribution of glutathione precursors in Arabidopsis thaliana.
Topics: Arabidopsis; Buthionine Sulfoximine; Cysteine; Dipeptides; Genetic Complementation Test; Glutamic Acid; Glutathione; Glycine; Mesophyll Cells; Mutation; Staining and Labeling; Subcellular Fractions | 2011 |
Benzimidazole conjugate of 1,1'-thiobis(2-naphthol) as switch-on fluorescence receptor for Ag+ and the complex as secondary recognition ensemble toward Cys, Asp, and Glu in aqueous methanolic solution: synthesis, characterization, ion and amino acid recog
Topics: Amino Acids; Aspartic Acid; Benzimidazoles; Cysteine; Fluorescent Dyes; Glutamic Acid; Ions; Magnetic Resonance Spectroscopy; Methanol; Silver; Solutions; Spectrophotometry, Ultraviolet; Water | 2012 |
The effect of intracellular amino acids on GSH production by high-cell-density cultivation of Saccharomyces cerevisiae.
Topics: Amino Acids; Cell Culture Techniques; Cysteine; Fermentation; Gas Chromatography-Mass Spectrometry; Glutamic Acid; Glutathione; Glycine; Intracellular Space; Metabolomics; Saccharomyces cerevisiae | 2012 |
Increased neuronal glutathione and neuroprotection in GTRAP3-18-deficient mice.
Topics: Analysis of Variance; Animals; Brain; Calcium-Binding Proteins; Carrier Proteins; Cysteine; Excitatory Amino Acid Transporter 3; Exploratory Behavior; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Glutamic Acid; Glutathione; Glycine; Heat-Shock Proteins; Hippocampus; In Vitro Techniques; Maze Learning; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Microfilament Proteins; Molsidomine; Motor Activity; Neurons; Nitric Oxide Donors; Phenotype; Phosphopyruvate Hydratase; Time Factors | 2012 |
Glutathione biosynthesis in bacteria by bifunctional GshF is driven by a modular structure featuring a novel hybrid ATP-grasp fold.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Crystallography, X-Ray; Cysteine; Dipeptides; Glutamate-Cysteine Ligase; Glutamic Acid; Glutathione; Glutathione Synthase; Glycine; Models, Molecular; Molecular Sequence Data; Pasteurella multocida; Protein Conformation; Streptococcus agalactiae | 2012 |
The Shigella flexneri effector OspI deamidates UBC13 to dampen the inflammatory response.
Topics: Adaptor Proteins, Signal Transducing; Amidohydrolases; Amino Acid Sequence; Animals; Aspartic Acid; B-Cell CLL-Lymphoma 10 Protein; Biocatalysis; Caspases; Catalytic Domain; Crystallography, X-Ray; Cysteine; Diglycerides; DNA Mutational Analysis; Dysentery, Bacillary; Glutamic Acid; Glutamine; HEK293 Cells; HeLa Cells; Histidine; Humans; Immunity, Innate; Inflammation; Mice; Models, Molecular; Molecular Sequence Data; Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein; Neoplasm Proteins; NF-kappa B; Shigella flexneri; TNF Receptor-Associated Factor 6; Ubiquitin-Conjugating Enzymes; Virulence Factors | 2012 |
Underestimation of pyruvic acid concentrations by fructose and cysteine in 2,4-dinitrophenylhydrazine-mediated onion pungency test.
Topics: Carbon-Sulfur Lyases; Chromatography, High Pressure Liquid; Color; Cysteine; Fructose; Glutamic Acid; Onions; Phenylhydrazines; Plant Roots; Pyruvic Acid | 2011 |
Crystal structures of Xanthomonas campestris OleA reveal features that promote head-to-head condensation of two long-chain fatty acids.
Topics: Bacterial Proteins; Catalytic Domain; Cerulenin; Coenzyme A; Cysteine; Fatty Acids; Glutamic Acid; Models, Molecular; Substrate Specificity; Xanthomonas campestris | 2012 |
Functional expression of system x(c)- is upregulated by asbestos but not crystalline silica in murine macrophages.
Topics: Amino Acid Transport System y+; Animals; Asbestos, Amphibole; Asbestos, Crocidolite; Biological Transport; Calcium Compounds; Cell Culture Techniques; Cell Line; Cell Survival; Cysteine; Dose-Response Relationship, Drug; Flow Cytometry; Glutamic Acid; Glutathione; Macrophages; Mice; Protein Subunits; Silicates; Silicon Dioxide; Up-Regulation | 2012 |
Intramolecular hydrogen transfer reactions of thiyl radicals from glutathione: formation of carbon-centered radical at Glu, Cys, and Gly.
Topics: Acetone; Amidines; Carbon; Cysteine; Deuterium Exchange Measurement; Deuterium Oxide; Free Radicals; Glutamic Acid; Glutathione; Glutathione Disulfide; Glycine; Hydrogen; Photolysis; Spectrometry, Mass, Electrospray Ionization; Ultraviolet Rays; Water | 2012 |
Structure and function of ∆1-tetrahydrocannabinolic acid (THCA) synthase, the enzyme controlling the psychoactivity of Cannabis sativa.
Topics: Animals; Berberine; Cannabis; Carbon Dioxide; Crystallography, X-Ray; Cysteine; Flavin-Adenine Dinucleotide; Glutamic Acid; Histidine; Intramolecular Oxidoreductases; Mutation; Protein Structure, Tertiary; Psychotropic Drugs; Structure-Activity Relationship; Tyrosine | 2012 |
Multiple sensor array of Mn2+, Fe2+, Co2+, Ni2+, Cu2+, and Zn2+ complexes of a triazole linked imino-phenol based calix[4]arene conjugate for the selective recognition of Asp, Glu, Cys, and His.
Topics: Aspartic Acid; Calixarenes; Cysteine; Glutamic Acid; Histidine; Imines; Models, Molecular; Molecular Structure; Organometallic Compounds; Phenols; Spectrometry, Fluorescence; Spectrometry, Mass, Electrospray Ionization; Transition Elements; Triazoles | 2012 |
A buried ionizable residue destabilizes the native state and the transition state in the folding of monellin.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Cysteine; Glutamic Acid; Hydrogen-Ion Concentration; Ions; Kinetics; Plant Proteins; Protein Folding; Protein Refolding; Protein Unfolding; Thermodynamics | 2012 |
Human immunodeficiency virus type 1 (HIV-1) transactivator of transcription through its intact core and cysteine-rich domains inhibits Wnt/β-catenin signaling in astrocytes: relevance to HIV neuropathogenesis.
Topics: AIDS Dementia Complex; Astrocytes; beta Catenin; Blotting, Western; Cell Line; Cysteine; Flow Cytometry; Gene Products, tat; Genes, Reporter; Glutamic Acid; HIV-1; Humans; Immunoprecipitation; Luciferases; Plasmids; Point Mutation; Real-Time Polymerase Chain Reaction; rev Gene Products, Human Immunodeficiency Virus; Signal Transduction; Transfection; Wnt Proteins | 2012 |
Metal-binding properties and structural characterization of a self-assembled coiled coil: formation of a polynuclear Cd-thiolate cluster.
Topics: Amino Acid Motifs; Biomimetic Materials; Cadmium; Chromatography, Gel; Circular Dichroism; Coordination Complexes; Crystallography, X-Ray; Cysteine; Glutamic Acid; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Light; Metalloproteins; Models, Molecular; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Peptides; Protein Structure, Secondary; Scattering, Radiation; Sulfhydryl Compounds | 2013 |
The P2X7 receptor as a route for non-exocytotic glutamate release: dependence on the carboxyl tail.
Topics: Adenosine Triphosphate; Animals; Calcium; Cysteine; Exocytosis; Glutamic Acid; HEK293 Cells; Humans; Rats; Receptors, Purinergic P2X7; Signal Transduction | 2013 |
The structural plasticity of the proximal [4Fe3S] cluster is responsible for the O2 tolerance of membrane-bound [NiFe] hydrogenases.
Topics: Crystallography, X-Ray; Cysteine; Ferrous Compounds; Glutamic Acid; Hydrogenase; Molecular Conformation; Oxidation-Reduction; Oxygen | 2013 |
Gating transitions in the palm domain of ASIC1a.
Topics: Acid Sensing Ion Channels; Animals; Cysteine; Electrophysiology; Epitopes; Glutamic Acid; Hydrogen-Ion Concentration; Hydrolysis; Ion Channel Gating; Mice; Molecular Conformation; Mutation; Protein Conformation; Protein Structure, Tertiary; Protons; Xenopus | 2013 |
Effects of the beta-lactam antibiotic ceftriaxone on nicotine withdrawal and nicotine-induced reinstatement of preference in mice.
Topics: Amino Acid Transport Systems; Animals; Anti-Bacterial Agents; Ceftriaxone; Conditioning, Psychological; Cysteine; Excitatory Amino Acid Transporter 2; Extinction, Psychological; Glutamic Acid; Male; Mice; Mice, Inbred ICR; Nicotine; Reinforcement, Psychology; Reward; Substance Withdrawal Syndrome; Tobacco Use Disorder | 2013 |
A redox 2-Cys mechanism regulates the catalytic activity of divergent cyclophilins.
Topics: Amino Acid Sequence; Binding Sites; Catalytic Domain; Citrus sinensis; Conserved Sequence; Crystallography, X-Ray; Cyclophilins; Cyclosporine; Cysteine; Disulfides; Glutamic Acid; Models, Molecular; Molecular Sequence Data; Oxidation-Reduction; Protein Conformation; RNA Polymerase II; Thioredoxins; Zinc | 2013 |
Structural and biochemical characterization of an active arylamine N-acetyltransferase possessing a non-canonical Cys-His-Glu catalytic triad.
Topics: Amino Acid Sequence; Arylamine N-Acetyltransferase; Bacillus cereus; Base Sequence; Catalytic Domain; Crystallography, X-Ray; Cysteine; DNA Primers; Glutamic Acid; Histidine; Models, Molecular; Molecular Sequence Data; Polymerase Chain Reaction; Protein Conformation; Recombinant Proteins; Sequence Homology, Amino Acid | 2013 |
A conformational intermediate in glutamate receptor activation.
Topics: Benzothiadiazines; Biophysical Phenomena; Cell Line, Transformed; Crystallography, X-Ray; Cysteine; Dithionitrobenzoic Acid; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; In Vitro Techniques; Membrane Potentials; Models, Molecular; Molecular Conformation; Mutation; Patch-Clamp Techniques; Phenanthrolines; Protein Structure, Tertiary; Quinoxalines; Receptors, Glutamate; Uncoupling Agents | 2013 |
The mechanism of the amidases: mutating the glutamate adjacent to the catalytic triad inactivates the enzyme due to substrate mispositioning.
Topics: Acrylamide; Amidohydrolases; Biocatalysis; Catalytic Domain; Crystallography, X-Ray; Cysteine; Enzyme Activation; Enzyme Stability; Geobacillus; Glutamic Acid; Mass Spectrometry; Mutant Proteins; Mutation; Oxidation-Reduction; Substrate Specificity | 2013 |
Bio-inspired band gap engineering of zinc oxide by intracrystalline incorporation of amino acids.
Topics: Amino Acids; Arginine; Biomimetic Materials; Crystallization; Cysteine; Feasibility Studies; Glutamic Acid; Microscopy, Electrochemical, Scanning; Nitrogen; Photoelectron Spectroscopy; Selenocysteine; Semiconductors; Serine; X-Ray Diffraction; Zinc Oxide | 2014 |
Mechanism of farnesylated CAAX protein processing by the intramembrane protease Rce1.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Archaeal Proteins; Biocatalysis; Conserved Sequence; Crystallography, X-Ray; Cysteine; DNA-Binding Proteins; Endopeptidases; Endoplasmic Reticulum; Escherichia coli Proteins; Glutamic Acid; Humans; Membrane Proteins; Metalloendopeptidases; Methanococcus; Mice; Models, Molecular; Molecular Sequence Data; Peptide Hydrolases; Prenylation; Protein Structure, Tertiary; Proto-Oncogene Proteins p21(ras); Signal Transduction; Substrate Specificity | 2013 |
Functional cardiovascular action of L-cysteine microinjected into pressor sites of the rostral ventrolateral medulla of the rat.
Topics: Animals; Blood Pressure; Cysteine; Glutamic Acid; Heart; Heart Rate; Male; Medulla Oblongata; Microinjections; Rats; Rats, Wistar | 2014 |
Crystal structure of glycoside hydrolase family 127 β-l-arabinofuranosidase from Bifidobacterium longum.
Topics: Amino Acid Sequence; Arabinose; Bifidobacterium; Catalytic Domain; Cysteine; Glutamic Acid; Glycoside Hydrolases; Models, Molecular; Molecular Sequence Data; Protein Structure, Tertiary; Quantum Theory; Sequence Alignment; Substrate Specificity; Zinc | 2014 |
Cysteine mutagenesis reveals alternate proximity between transmembrane domain 2 and hairpin loop 1 of the glutamate transporter EAAT1.
Topics: Amino Acid Sequence; Aspartic Acid; Cadmium Chloride; Cross-Linking Reagents; Cysteine; Dithiothreitol; Excitatory Amino Acid Transporter 1; Glutamic Acid; HeLa Cells; Humans; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenanthrolines; Protein Structure, Tertiary; Structure-Activity Relationship | 2014 |
Use of cysteine-reactive cross-linkers to probe conformational flexibility of human DJ-1 demonstrates that Glu18 mutations are dimers.
Topics: Algorithms; Circular Dichroism; Cross-Linking Reagents; Crystallization; Cysteine; Dimerization; Glutamic Acid; HEK293 Cells; Hot Temperature; Humans; Indicators and Reagents; Intracellular Signaling Peptides and Proteins; Magnetic Resonance Spectroscopy; Molecular Weight; Mutation; Nitrogen Isotopes; Oncogene Proteins; Oxidation-Reduction; Protein Conformation; Protein Deglycase DJ-1; Recombinant Proteins; Solvents; Ultracentrifugation | 2014 |
Structure of an agonist-bound ionotropic glutamate receptor.
Topics: Animals; Cross-Linking Reagents; Crystallography, X-Ray; Cysteine; Glutamic Acid; HEK293 Cells; Humans; Ion Channel Gating; Models, Chemical; Organophosphonates; Protein Structure, Secondary; Protein Structure, Tertiary; Pyrimidinones; Quinoxalines; Rats; Receptors, AMPA | 2014 |
Identification of catalytic residues of a very large NAD-glutamate dehydrogenase from Janthinobacterium lividum by site-directed mutagenesis.
Topics: Amino Acid Sequence; Bacterial Proteins; Binding Sites; Biocatalysis; Burkholderiaceae; Cysteine; Enzyme Assays; Gene Expression; Glutamate Dehydrogenase; Glutamic Acid; Kinetics; Mercuric Chloride; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Protein Binding; Protein Structure, Tertiary; Protein Subunits; Sequence Homology, Amino Acid; Structure-Activity Relationship | 2014 |
Theoretical study of enzymatic catalysis explains why the trapped covalent intermediate in the E303C mutant of glycosyltransferase GTB was not detected in the wild-type enzyme.
Topics: Amino Acid Substitution; Binding Sites; Biocatalysis; Cysteine; Galactosyltransferases; Glutamic Acid; Humans; Kinetics; Mass Spectrometry; Models, Chemical; Mutation; Protein Binding; Protein Conformation; Quantum Theory; Substrate Specificity; Thermodynamics | 2015 |
Cysteine transport through excitatory amino acid transporter 3 (EAAT3).
Topics: Animals; Cysteine; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; Glutamic Acid; HEK293 Cells; Humans; Hydrogen-Ion Concentration; Oocytes; Selenocysteine; Xenopus | 2014 |
L-Cysteine and L-AP4 microinjections in the rat caudal ventrolateral medulla decrease arterial blood pressure.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aminobutyrates; Anesthetics; Animals; Arterial Pressure; Cardiovascular Agents; Cysteine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Heart Rate; Male; Medulla Oblongata; Microinjections; Rats, Wistar; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Urethane | 2014 |
Expression of xCT as a predictor of disease recurrence in patients with colorectal cancer.
Topics: Aged; Biomarkers, Tumor; Colorectal Neoplasms; Cysteine; Female; Glutamic Acid; Humans; Hyaluronan Receptors; Male; Middle Aged; Recurrence; Risk Factors | 2015 |
Prion protein regulates glutathione metabolism and neural glutamate and cysteine uptake via excitatory amino acid transporter 3.
Topics: Animals; Astrocytes; Cells, Cultured; Cerebellum; CHO Cells; Cricetulus; Cysteine; Excitatory Amino Acid Agents; Excitatory Amino Acid Transporter 3; Female; Fluoresceins; Glutamic Acid; Glutathione; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Neurons; Prions | 2015 |
Cadmium-cysteine coordination in the BK inner pore region and its structural and functional implications.
Topics: Amino Acid Sequence; Animals; Cadmium; Crystallography, X-Ray; Cysteine; Glutamic Acid; Intracellular Space; Ion Channel Gating; Large-Conductance Calcium-Activated Potassium Channels; Models, Molecular; Molecular Sequence Data; Mutant Proteins; Protein Subunits; Structure-Activity Relationship; Xenopus | 2015 |
In Vitro Study of L-Glutamate and L-Glutamine Transport in Retinal Pericytes: Involvement of Excitatory Amino Acid Transporter 1 and Alanine-Serine-Cysteine Transporter 2.
Topics: Alanine; Amino Acid Transport System ASC; Animals; Aspartic Acid; Cysteine; Excitatory Amino Acid Transporter 1; Glutamic Acid; Glutamine; Ion Transport; Male; Minor Histocompatibility Antigens; Pericytes; Rats, Wistar; Retina; Serine | 2015 |
Taste-active compound levels in Korean native chicken meat: The effects of bird age and the cooking process.
Topics: Aging; Animals; Carbohydrates; Chickens; Cooking; Cysteine; Fatty Acids; Glutamic Acid; Inosine Monophosphate; Meat; Republic of Korea; Taste | 2015 |
Regulation of brain glutamate metabolism by nitric oxide and S-nitrosylation.
Topics: Amino Acid Sequence; Animals; Blotting, Western; Brain; Chromatography, Liquid; Cysteine; Excitatory Amino Acid Transporter 2; Glutamic Acid; Glutamine; HEK293 Cells; Humans; Male; Mice, Inbred C57BL; Mice, Knockout; Molecular Sequence Data; Mutation; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Proteome; Proteomics; Rats; S-Nitrosothiols; Tandem Mass Spectrometry | 2015 |
Disruption of S2-M4 linker coupling reveals novel subunit-specific contributions to N-methyl-d-aspartate receptor function and ethanol sensitivity.
Topics: Animals; Cysteine; Dose-Response Relationship, Drug; Ethanol; Glutamic Acid; Glycine; HEK293 Cells; Humans; Ion Channel Gating; Protein Structure, Tertiary; Rats; Receptors, N-Methyl-D-Aspartate | 2016 |
Characterization of bifunctional L-glutathione synthetases from Actinobacillus pleuropneumoniae and Actinobacillus succinogenes for efficient glutathione biosynthesis.
Topics: Actinobacillus; Actinobacillus pleuropneumoniae; Adenosine Triphosphate; Bacterial Proteins; Cloning, Molecular; Cysteine; Dipeptides; Escherichia coli; Glutamic Acid; Glutathione; Glutathione Synthase; Glycine; Hydrogen-Ion Concentration; Pasteurella multocida; Protein Conformation; Streptococcus agalactiae; Streptococcus thermophilus | 2016 |
Dihydrostreptomycin Directly Binds to, Modulates, and Passes through the MscL Channel Pore.
Topics: Anti-Bacterial Agents; Binding Sites; Cell Membrane; Cysteine; Dihydrostreptomycin Sulfate; Escherichia coli; Escherichia coli Proteins; Glutamic Acid; Ion Channel Gating; Ion Channels; Mechanoreceptors; Molecular Docking Simulation; Molecular Dynamics Simulation; Mutation; Potassium; Protein Binding; Protein Conformation | 2016 |
Paracrine Induction of HIF by Glutamate in Breast Cancer: EglN1 Senses Cysteine.
Topics: Amino Acid Transport System y+; Animals; Breast Neoplasms; Cysteine; Glutamic Acid; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Hypoxia-Inducible Factor-Proline Dioxygenases; MCF-7 Cells; Mice; Paracrine Communication; Triple Negative Breast Neoplasms | 2016 |
Transport of BMAA into Neurons and Astrocytes by System x
Topics: Amino Acid Transport Systems; Amino Acids, Diamino; Animals; Aspartic Acid; Astrocytes; Carbon Isotopes; Cells, Cultured; Cerebral Cortex; Cyanobacteria Toxins; Cysteine; Embryo, Mammalian; Female; Glutamic Acid; Glutathione; Mice; Neurons; Neurotransmitter Uptake Inhibitors; Pregnancy; Sulfasalazine; Time Factors | 2018 |
Optimization of Inexpensive Agricultural By-Products as Raw Materials for Bacitracin Production in Bacillus licheniformis DW2.
Topics: Bacillus licheniformis; Bacitracin; Brassica rapa; Cysteine; Glutamic Acid; Glycine max | 2017 |
Urinary metabolic insights into host-gut microbial interactions in healthy and IBD children.
Topics: Adolescent; Anthropometry; Bile Acids and Salts; Body Composition; Case-Control Studies; Child; Colitis, Ulcerative; Crohn Disease; Cysteine; Female; Gas Chromatography-Mass Spectrometry; Gastrointestinal Microbiome; Glutamic Acid; Glutathione; Glycine; Humans; Inflammation; Inflammatory Bowel Diseases; Male; Metabolome; Metabolomics; Microbial Interactions; Phenotype; Pyrrolidonecarboxylic Acid; Signal Transduction; Urine | 2017 |
Continuous High-Throughput Colorimetric Assays for α-Transaminases.
Topics: Colorimetry; Cysteine; Glutamic Acid; High-Throughput Screening Assays; Keto Acids; Transaminases | 2018 |
Oncogenic PI3K promotes methionine dependency in breast cancer cells through the cystine-glutamate antiporter xCT.
Topics: Amino Acid Transport System y+; Breast Neoplasms; Carcinogenesis; Cell Line; Cell Proliferation; Class I Phosphatidylinositol 3-Kinases; Cysteine; Cystine; Female; Gene Expression; Glutamic Acid; Homocysteine; Humans; Mammary Glands, Human; MCF-7 Cells; Methionine; Mutation | 2017 |
Highly sensitive microfluidic paper-based photoelectrochemical sensing platform based on reversible photo-oxidation products and morphology-preferable multi-plate ZnO nanoflowers.
Topics: Biosensing Techniques; Cysteine; Electrochemical Techniques; Electron Transport; Equipment Design; Glutamic Acid; Limit of Detection; Microfluidic Analytical Techniques; Molecular Imprinting; Nanostructures; Oxidation-Reduction; Paper; Photochemical Processes; Zinc Oxide | 2018 |
Cysteine Scanning Mutagenesis of TM4b-4c Loop of Glutamate Transporter EAAT1 Reveals Three Conformationally Sensitive Residues.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Biological Transport; Cysteine; Excitatory Amino Acid Transporter 1; Glutamic Acid; HeLa Cells; Humans; Mutagenesis; Potassium; Protein Structure, Secondary; Rats; Structure-Activity Relationship; Tetraspanins | 2018 |
Sulfite protects neurons from oxidative stress.
Topics: Animals; Brain; Cells, Cultured; Cysteine; Ferroptosis; Glutamic Acid; Glutathione; L-Lactate Dehydrogenase; Neurons; Neuroprotective Agents; Oxidative Stress; Rats, Sprague-Dawley; Sulfites | 2019 |
Metabolic profiles of cysteine, methionine, glutamate, glutamine, arginine, aspartate, asparagine, alanine and glutathione in Streptococcus thermophilus during pH-controlled batch fermentations.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Culture Media; Cysteine; Fermentation; Glutamic Acid; Glutamine; Glutathione; Hydrogen-Ion Concentration; Metabolic Networks and Pathways; Metabolome; Methionine; Nitrogen; Streptococcus thermophilus | 2018 |
Arabidopsis γ-glutamylcyclotransferase affects glutathione content and root system architecture during sulfur starvation.
Topics: Arabidopsis; Arabidopsis Proteins; Buthionine Sulfoximine; Cysteine; DNA, Bacterial; gamma-Glutamylcyclotransferase; Gene Expression Regulation, Plant; Glutamic Acid; Glutathione; Meristem; Models, Biological; Mutation; Phenotype; Plant Roots; Promoter Regions, Genetic; RNA, Messenger; Sulfur | 2019 |
Protective role of l-glutamic acid and l-cysteine in mitigation the chlorpyrifos-induced oxidative stress in rats.
Topics: Animals; Antioxidants; Chlorpyrifos; Cholinesterase Inhibitors; Cysteine; Drug Interactions; Glutamic Acid; Insecticides; Male; Oxidative Stress; Rats, Wistar | 2018 |
Cysteine SH and Glutamate COOH Contributions to [NiFe] Hydrogenase Proton Transfer Revealed by Highly Sensitive FTIR Spectroscopy.
Topics: Cysteine; Glutamic Acid; Humans; Hydrogenase; Protons; Spectroscopy, Fourier Transform Infrared | 2019 |
Efficient production of glutathione with multi-pathway engineering in Corynebacterium glutamicum.
Topics: Corynebacterium glutamicum; Cysteine; Glutamic Acid; Glutathione; Glycine; Metabolic Engineering; Metabolic Networks and Pathways; Serine | 2019 |
Loss of the mitochondrial lipid cardiolipin leads to decreased glutathione synthesis.
Topics: Cardiolipins; Cysteine; Ferrous Compounds; Glutamic Acid; Glutathione; Hydrogen Peroxide; Membrane Proteins; Mitochondria; Oxidative Stress; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Transferases (Other Substituted Phosphate Groups) | 2020 |
Aqueous Preparation of Maillard Reaction Intermediate from Glutathione and Xylose and its Volatile Formation During Thermal Treatment.
Topics: Cysteine; Flavoring Agents; Glutamic Acid; Glutathione; Glycation End Products, Advanced; Glycine; Hot Temperature; Maillard Reaction; Vacuum; Xylose | 2019 |
A synthetic lethal drug combination mimics glucose deprivation-induced cancer cell death in the presence of glucose.
Topics: Amino Acid Transport System y+; Antineoplastic Combined Chemotherapy Protocols; Antiporters; Cell Death; Cell Line, Tumor; Cell Survival; Cysteine; Cystine; Dimerization; Glucose; Glucose Transporter Type 1; Glutamic Acid; Glutathione; Humans; Metabolome; NADP; Neoplasms; Oxidation-Reduction; Reactive Oxygen Species; Synthetic Drugs | 2020 |
Structure and dynamics at N- and C-terminal regions of intrinsically disordered human c-Myc PEST degron reveal a pH-induced transition.
Topics: Amino Acid Sequence; Aspartic Acid; Cloning, Molecular; Cysteine; Escherichia coli; Gene Expression; Genetic Vectors; Glutamic Acid; Humans; Hydrogen-Ion Concentration; Indoles; Intrinsically Disordered Proteins; Molecular Dynamics Simulation; Neoplasm Proteins; Phosphatidylcholines; Protein Folding; Protein Structure, Secondary; Proto-Oncogene Proteins c-myc; Recombinant Proteins; Spectrometry, Fluorescence; Staining and Labeling; Tryptophan | 2020 |
3,6-Anhydro-L-Galactose Dehydrogenase VvAHGD is a Member of a New Aldehyde Dehydrogenase Family and Catalyzes by a Novel Mechanism with Conformational Switch of Two Catalytic Residues Cysteine 282 and Glutamate 248.
Topics: Amino Acid Sequence; Binding Sites; Catalysis; Cysteine; Galactose; Galactose Dehydrogenases; Glutamic Acid; Models, Molecular; Mutation; NADP; Phylogeny; Sequence Homology; Vibrio | 2020 |
Quinidine partially blocks mitochondrial voltage-dependent anion channel (VDAC).
Topics: Animals; Anions; Crystallography, X-Ray; Cysteine; Female; Glutamic Acid; Inhibitory Concentration 50; Male; Mitochondria; Molecular Docking Simulation; Neurons; Oxidative Phosphorylation; Protein Structure, Secondary; Quinidine; Rats; Rats, Wistar; Spectrometry, Fluorescence; Voltage-Dependent Anion Channel 1; Voltage-Dependent Anion Channel 2 | 2020 |
Cadmium activates AMPA and NMDA receptors with M3 helix cysteine substitutions.
Topics: Cadmium; Cysteine; Glutamic Acid; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate | 2020 |
Structural Insights into the Mechanism of the Radical SAM Carbide Synthase NifB, a Key Nitrogenase Cofactor Maturating Enzyme.
Topics: Archaeal Proteins; Binding Sites; Crystallography, X-Ray; Cysteine; Glutamic Acid; Histidine; Iron-Sulfur Proteins; Methanosarcinales; Models, Chemical; Oxidoreductases; Protein Binding; Protein Conformation; S-Adenosylmethionine | 2020 |
An Unsual Cys-Glu-Lys Catalytic Triad is Responsible for the Catalytic Mechanism of the Nitrilase Superfamily: A QM/MM Study on Nit2.
Topics: Aminohydrolases; Animals; Biocatalysis; Cysteine; Density Functional Theory; Glutamic Acid; Lysine; Mice; Models, Molecular | 2021 |
Optimization of Reaction Conditions for γ-Glutamylcysteine Production from Glutathione Using a Phytochelatin Synthase-Like Enzyme from Nostoc sp. Pasteur Culture Collection 7120.
Topics: Amino Acid Sequence; Aminoacyltransferases; Antioxidants; Buffers; Catalysis; Chemistry, Pharmaceutical; Cysteine; Dipeptides; Glutamic Acid; Glutathione; Humans; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Nostoc; Phytochelatins; Temperature | 2021 |
Molecular basis for redox control by the human cystine/glutamate antiporter system xc
Topics: Amino Acid Transport System y+; Antiporters; Biochemistry; Cryoelectron Microscopy; Cysteine; Cystine; Fusion Regulatory Protein 1, Heavy Chain; Glutamic Acid; Glutathione; HEK293 Cells; Humans; Neoplasms; Oxidation-Reduction; Reactive Oxygen Species; Up-Regulation | 2021 |
Role of Water in Proton-Coupled Electron Transfer between Tyrosine and Cysteine in Ribonucleotide Reductase.
Topics: Cysteine; Electron Transport; Electrons; Escherichia coli; Free Radicals; Glutamic Acid; Models, Molecular; Protons; Ribonucleotide Reductases; Tyrosine; Water | 2022 |
Rapid, sensitive analysis method for determining the nitrogen stable isotope ratio of total free amino acids in soil.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cysteine; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Histidine; Leucine; Lysine; Nitrogen; Nitrogen Isotopes; Phenylalanine; Serine; Soil; Tryptophan | 2022 |
Glutamic Acid and Poly-γ-glutamic Acid Enhanced the Heat Resistance of Chinese Cabbage (
Topics: Abscisic Acid; Anions; Ascorbate Peroxidases; Brassica; Brassica rapa; Catalase; Chlorophyll; Cysteine; Glucosinolates; Glutamic Acid; Glutathione; Linoleic Acid; Malondialdehyde; Methionine; Oxides; Photosynthesis; Polyglutamic Acid; Purines; Pyrimidines; Reactive Oxygen Species; Superoxide Dismutase | 2022 |
Metabolomics study based on GC-MS reveals a protective function of luteolin against glutamate-induced PC12 cell injury.
Topics: Animals; Cysteine; Gas Chromatography-Mass Spectrometry; Glutamic Acid; Luteolin; Metabolomics; PC12 Cells; Rats | 2023 |