glutamic acid has been researched along with asparagine in 289 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 36 (12.46) | 18.7374 |
| 1990's | 77 (26.64) | 18.2507 |
| 2000's | 132 (45.67) | 29.6817 |
| 2010's | 34 (11.76) | 24.3611 |
| 2020's | 10 (3.46) | 2.80 |
| Authors | Studies |
|---|---|
| Akamatsu, M; Asao, M; Fujita, T; Iwamura, H | 1 |
| Cha, SH; Chairoungdua, A; Endou, H; Kanai, Y; Kim, DK; Matsuo, H | 1 |
| Crespeau, H; Ferri, G; Galliano, M; Minchiotti, L; Porta, F; Rochu, D; Stoppini, M | 1 |
| Ormandy, GC | 1 |
| Dauth, J; Nkhumeleni, FS; Pitout, MJ; Raubenheimer, EJ; Smith, PD; van Heerden, WF | 1 |
| David, CL; Farnum, MF; Howell, EE; Kraut, J; Oatley, SJ; Villafranca, JE | 1 |
| Rupitz, K; Trimbur, D; Warren, RA; Withers, SG | 1 |
| Béguin, P; Navas, J | 1 |
| Burnashev, N; Günther, W; Monyer, H; Ruppersberg, JP; Sakmann, B; Schoepfer, R; Seeburg, PH | 1 |
| Wright, HT | 1 |
| Flott, B; Seifert, W | 1 |
| Chen, MW; Ishino, Y; Jahn, D; Kim, YC; Söll, D | 1 |
| Goodman, JC; Robertson, CS; Simpson, RK | 1 |
| Heger, J | 1 |
| Nathans, J | 1 |
| Bauman, MJ; Mawhinney, TD; Peterson, E; Rarey, KE; Raymer, SL; Schweitzer, VG; Woodson, BT | 1 |
| Boxer, SG; Gray, HB; Varadarajan, R; Zewert, TE | 1 |
| Daly, MP; Demediuk, P; Faden, AI | 1 |
| Eisenstein, E; Markby, DW; Schachman, HK | 1 |
| Bell, EF; Filer, LJ; Stegink, LD; Tephly, TR; Ziegler, EE | 1 |
| Clarke, DM; Inesi, G; Leberer, E; Loo, TW; MacLennan, DH; Maruyama, K | 1 |
| Meessen, S; Oesterhelt, D; Otomo, J; Soppa, J; Straub, J; Tittor, J | 1 |
| Ahl, PL; Berkowitz, S; Duñach, M; Khorana, HG; Marti, T; Mogi, T; Rothschild, KJ; Stern, LJ | 1 |
| Cole, DE; Holcenberg, JS; Jolivet, J; Poplack, DG | 1 |
| Canellakis, ES; Fong, WF; Ortiz, JG; Rinehart, CA; Viceps-Madore, D | 1 |
| Arst, HN; Grenson, M; Wiame, JM | 1 |
| Joy, K; Ta, TC | 1 |
| Fang, GH; Hager, LP; Kenigsberg, P | 1 |
| Bell, EF; Brummel, MC; Filer, LJ; Krause, WL; Stegink, LD; Wolf-Novak, LC; Ziegler, EE | 1 |
| Yokoi, I | 1 |
| Candelore, MR; Dixon, RA; Hill, WS; Rands, E; Sigal, IS; Strader, CD | 1 |
| Nishimura, K; Noda, S; Ohta, M; Oyama, N; Shiota, M; Sogabe, N; Sugano, T | 1 |
| Chance, WT; Enrione, EB; Popp, MB; Wagner, SC | 1 |
| Krakhmaleva, IN; Petiushenko, RM; Telesnina, GN | 1 |
| Coleman, PS; Lavietes, BB | 1 |
| Mangano, RM; Schwarcz, R | 1 |
| Cuénod, M; Henke, H; Toggenburger, G; Wiklund, L | 1 |
| Applebaum, FR; Dennis, MB; Detter, JC; Holcenberg, JS; Newman, ML; Rastelli, LN; Schmer, G | 1 |
| Brooksbank, RL; Mizrahi, V; Nkabinde, NC | 1 |
| Baker, RT; Varshavsky, A | 1 |
| Li, L; Liu, D; McAdoo, DJ; Yang, J | 1 |
| Niwa, A; Sawai, T; Someya, Y; Yamaguchi, A | 1 |
| Ishida, M; Kataoka, K; Nakamura, Y; Shinozaki, H | 1 |
| Beck, M; Fahmy, K; Jäger, F; Sakmar, TP; Siebert, F; Zvyaga, TA | 1 |
| Akasaka, T; O'yauchi, R; Sawai, T; Someya, Y; Yamaguchi, A | 1 |
| Bartolone, L; Benvenga, S; Filetti, S; Pontecorvi, A; Regalbuto, C; Trimarchi, F | 1 |
| Ahlman, B; Andersson, K; Hedenborg, L; Leijonmarck, CE; Ljungqvist, O; Wernerman, J | 1 |
| Djamgoz, MB; Stephens, GJ; Wilkin, GP | 1 |
| Cohen, A; Jones, LA; Kane, K; Milunsky, A; Myles, N; Skare, J; Skinner, M | 1 |
| Hansen, L; Suzdak, PD; Thomsen, C | 1 |
| Brammar, WJ; Conley, EC; Davies, NW; Khan, IA; Shelton, PA; Stanfield, PR; Sutcliffe, MJ | 1 |
| Pow, DV | 1 |
| Fedele, E; Foster, AC | 1 |
| Günther, W; Jahn, W; Kuner, T; Raditsch, M; Ruppersberg, JP; Schoepfer, R; Seeburg, PH; Witzemann, V | 1 |
| Brocklehurst, K; Mellor, GW; Patel, M; Thomas, EW | 1 |
| Angelini, GD; Birkett, S; Suleiman, MS; Wallace, D | 2 |
| Ellis, SW; Hayhurst, GP; Lennard, MS; Mackman, R; Ortiz de Montellano, PR; Smith, G; Tschirret-Guth, RA; Tucker, GT; Wolf, CR | 1 |
| Haselkorn, R; Zheng, S | 1 |
| Arenas, J; Benito-León, J; Cisneros, E; Gasalla, T; Gómez, P; Jiménez-Jiménez, FJ; Molina, JA; Navarro, JA; Ortí-Pareja, M; Vargas, C | 1 |
| Ahlke, E; Boos, J; Jürgens, H; Nowak-Göttl, U; Ritter, J; Schulze-Westhoff, P; Verspohl, EJ; Werber, G; Würthwein, G | 1 |
| Christensen, U; Olsen, K; Stoffer, BB; Svensson, B | 1 |
| Deitmer, JW; Schneider, HP | 1 |
| Miyazaki, K; Oshima, T; Yaoi, T | 1 |
| Calderón, J; Du Pont, G; Durán, S; Huerta-Zepeda, A; Lloret, A; Merchant-Larios, H; Ortuño, L | 1 |
| Akanuma, S; Oshima, T; Qu, C; Tanaka, N; Yamagishi, A | 1 |
| Bing, W; Esposito, G; Marston, SB; Purcell, IF; Redwood, CS; Watkins, H | 1 |
| Pesty, FH; Sultan, F | 1 |
| Abildgaard, S; Jensen, G; Nordestgaard, BG; Steffensen, R; Tybjaerg-Hansen, A; Wittrup, HH | 1 |
| Feng, Y; Swenson, RP | 1 |
| Kempski, OS; Kossmann, T; Lowitzsch, K; Morganti-Kossmann, MC; Pleines, UE; Stover, JF | 1 |
| Brandt, U; Meunier, B; Ortwein, C; Rich, PR | 1 |
| Endo, K; Esaki, N; Fuchikami, Y; Kishimoto, K; Liu, L; Manning, JM; Soda, K; Yoshimura, T | 1 |
| Nomura, T; Okamoto, K; Yamanaka, H | 1 |
| Behr, J; Hellwig, P; Ludwig, B; Mäntele, W; Michel, H; Odenwald, A; Ostermeier, C; Pfitzner, U; Richter, OM | 1 |
| Beck, M; Sakmar, TP; Siebert, F | 1 |
| Birdsall, DL; Finer-Moore, J; Huang, W; Santi, DV; Stroud, RM | 1 |
| Finazzi, G; Joliot, P; Wollman, FA; Zito, F | 1 |
| Ekberg, M; Nordlund, P; Pötsch, S; Sahlin, M; Sandin, E; Sjöberg, BM; Thunnissen, M | 1 |
| Munagala, NR; Wang, CC | 1 |
| Cavagnero, S; Dyson, HJ; Wright, PE | 1 |
| Herscovics, A; Lipari, F | 1 |
| Bonn, G; Fiechtner, B; Glossmann, H; Huck, CW; Moebius, FF; Soellner, KE | 1 |
| Abcouwer, SF; Souba, WW | 1 |
| Adachi, T; Chikushi, K; Mitsunaga, T; Shimizu, M; Watanabe, K; Yoshida, T | 1 |
| Camici, G; Chiti, F; Fiaschi, T; Manao, G; Paoli, P; Ramponi, G; Raugei, G; Taddei, N; Veggi, D | 1 |
| Blanchard, CZ; Frantom, PA; Lee, YM; Waldrop, GL | 1 |
| Kass, IJ; Sampson, NS; Vrielink, A; Yue, QK | 1 |
| Jung, CM; Katayama, S; Matsushita, O; Minami, J; Okabe, A; Sakurai, J | 1 |
| Hara, K; Hijikata, Y; Hiraoka, E; Ogawa, N; Takahashi, H | 1 |
| Green, EL; Klinman, JP; Plastino, J; Sanders-Loehr, J | 1 |
| Jaeger, J; Knowles, PF; McPherson, MJ; Murray, JM; Phillips, SE; Saysell, CG; Tambyrajah, WS; Wilmot, CM | 1 |
| Kvamme, E; Roberg, B; Torgner, IA | 1 |
| Chen, CC; Herzberg, O | 2 |
| El-Sherif, Y; Khan, T; Singh, N; Wieraszko, A | 1 |
| Edskes, HK; Hanover, JA; Wickner, RB | 1 |
| Kempski, OS; Stover, JF | 1 |
| Abdel Ghani, EM; Bhakdi, S; Kehoe, M; Palmer, M; Walev, I; Weis, S | 1 |
| Kühlbrandt, W; Rogl, H | 1 |
| Ibarra-Molero, B; Loladze, VV; Makhatadze, GI; Sanchez-Ruiz, JM | 1 |
| Gonda, TJ; McCormack, MP | 1 |
| Choi, G; Choi, KY; Ha, NC; Kim, DH; Kim, SW; Oh, BH; Park, S | 1 |
| Lacount, MW; Lebioda, L; Lewinski, K; Ortlund, E | 1 |
| Corzo, N; del Castillo, MD; Olano, A; Sanz, ML | 1 |
| Moriyama, Y | 1 |
| Bienengraeber, M; Echtay, KS; Klingenberg, M; Winkler, E | 1 |
| Dove, JE; Klinman, JP; Schwartz, B; Williams, NK | 1 |
| Avaeva, SM; Kurilova, SA; Nazarova, TI; Polyakov, KM; Rodina, EV; Samygina, VR; Vorobyeva, NN | 1 |
| Hinchliffe, SJ; Morgan, BP | 1 |
| Eswar, N; Ramakrishnan, C | 1 |
| Alexov, E; Baciou, L; Gunner, MR; Hanson, DK; Miksovska, J; Schiffer, M; Sebban, P | 1 |
| Collins, MA; Ordal, GW; Tiu, J; Zimmer, MA | 1 |
| Brayer, GD; Joshi, MD; McIntosh, LP; Pot, I; Sidhu, G; Withers, SG | 1 |
| Bing, W; Esposito, G; Knott, A; Marston, S; Purcell, I; Redwood, C; Watkins, H | 1 |
| Aliev, ZN | 1 |
| Haynes, TE; Li, H; Meininger, CJ; Wu, G | 1 |
| Ebanks, RO; Isenman, DE; Pan, Q | 1 |
| Brennan, RG; Goodman, RH; Schumacher, MA | 1 |
| Carter, CE; Goodenough, PW; Marriage, H | 1 |
| Takano, K; Tsuchimori, K; Yamagata, Y; Yutani, K | 1 |
| Doyle, SA; Fung, SY; Koshland, DE | 1 |
| Kraynov, VS; Liu, J; Showalter, AK; Tsai, MD; Zhong, X | 1 |
| Hwang, JJ; Stupp, SI | 1 |
| Agrawal, A; Greenhough, TJ; Shrive, AK; Volanakis, JE | 1 |
| Canyuk, B; Eakin, AE; Focia, PJ | 1 |
| Kumar, K; Walz, FG | 1 |
| Brenner, E; Chiu, J; Coruzzi, G; Hsieh, MH; Kouranov, A; Lam, HM; Oliveira, IC; Shin, MJ | 1 |
| Makinen, MW; Mustafi, D; Sosa-Peinado, A | 1 |
| Eisenberg, D; Gill, HS | 1 |
| Christensen, T; DiTusa, CA; Fierke, CA; Mahapatro, M; McCall, KA; Toone, EJ | 1 |
| Irún, MP; Maldonado, S; Sancho, J | 1 |
| Glavas, S; Tanner, ME | 1 |
| Ballou, DP; Ludwig, ML; Matthews, RG; Trimmer, EE | 1 |
| Jordan, F; Sergienko, EA | 1 |
| Gabriel, A; Uzun, O | 1 |
| Lee, VT; Mazmanian, SK; Schneewind, O | 1 |
| Baranov, V; Hörstedt, P; Ippel, HJ; Lundgren, E; Olofsson, A; Wijmenga, S | 1 |
| Fukui, Y; Jung, YG; Lee, ES; Sakata, T | 1 |
| Breton, J; Nabedryk, E; Okamura, MY; Paddock, ML | 1 |
| Arlaud, GJ; Chevallier, S; Tacnet-Delorme, P | 1 |
| Corvol, P; Iturrioz, X; Llorens-Cortes, C; Michaud, A; Rozenfeld, R | 1 |
| Cavagnero, S; Dyson, HJ; Nishimura, C; Schwarzinger, S; Wright, PE | 1 |
| Ramos, JL; Ruiz, R | 1 |
| Jacobsen, MD; Jorgensen, PL; Pedersen, PA | 1 |
| Collins-Racie, LA; Fosang, AJ; Hebert, T; Last, K; LaVallie, ER; McDonagh, T; Morris, EA; Sandy, JD; Thompson, VP; Tomkinson, KN; Westling, J | 1 |
| Palecz, B | 1 |
| Goto, N; Igarashi, T; Morisaki, H; Yamamoto, A | 1 |
| Inokuchi, N; Irie, M; Itagaki, T; Iwama, M; Kobayashi, H; Ogawa, Y; Ohgi, K; Tsuji, T | 1 |
| Ayukarn, K; Changtrakun, Y; Fucharoen, G; Fucharoen, S; Sanchaisuriya, K; Siriratmanawong, N | 1 |
| Brennan, TJ; Sluka, KA; Zahn, PK | 1 |
| Bohác, M; Damborský, J; Koca, J; Monincová, M; Nagata, Y; Prokop, M; Prokop, Z; Tsuda, M | 1 |
| Almo, SC; Cahill, SM; Evans, GB; Fedorov, A; Furneaux, RH; Kicska, GA; Lewandowicz, A; Schramm, VL; Shi, W; Tyler, PC | 1 |
| Ferry, JG; Rowlett, RS; Silverman, DN; Tripp, BC; Tu, C | 1 |
| Carrick, KL; Topal, MD | 1 |
| Chung, SJ; Norman, DP; Verdine, GL | 1 |
| Bruzik, KS; Kravchuk, AV; Tsai, MD; Zhao, L | 1 |
| Ishikita, H; Knapp, EW; Morra, G | 1 |
| Galili, G; Zhu, X | 1 |
| Hernandez, M; Jatzke, C; Wollmuth, LP | 1 |
| Aldred, S; Fitzgerald, M; Moore, KM; Waring, RH | 1 |
| Lorca, G; Saier, MH; Winnen, B | 1 |
| Oliver, J; Palou, A; Proenza, AM; Roca, P | 1 |
| Nau, C; Wang, GK; Wang, SY | 1 |
| Ali, Z; Baker, G; Guterman, LR; Hopkins, LN; Qureshi, AI; Shuaib, A; Suri, MF; Todd, K | 1 |
| Almo, SC; Fedorov, AA; Sun, JP; Wu, L; Zhang, ZY | 1 |
| Daiho, T; Danko, S; Iizuka, H; Suzuki, H; Wang, G; Yamasaki, K | 1 |
| Dawson, JP; Deber, CM; Engelman, DM; Melnyk, RA | 1 |
| Ajlouni, A; Beucler, I; Bruckert, E; Chadarevian, R; Foubert, L; Giral, P; Kottler, ML; Raisonnier, A; Turpin, G | 1 |
| Barry, BA; Halverson, KM; Sachs, RK | 1 |
| Cunchillos, C; Lecointre, G | 1 |
| SARMA, PS; SIVARAMAKRISHNAN, VM | 1 |
| BESSMAN, SP; MEISTER, A; UDENFRIEND, S | 1 |
| BAISDEN, LA; GROTH, AH; JOHNSON, HW; LARSEN, AB | 1 |
| WOESE, CR | 1 |
| CAMERON, HS; MEYER, ME | 1 |
| DIABLOVA, PE | 1 |
| COLE, AG; HUTCHENS, JO; ROBIE, RA; STOUT, JW | 1 |
| PANALAKS, T; SMITH, MD; WALKER, EI | 1 |
| EHRENFELD, E; MARBLE, SJ; MEISTER, A | 1 |
| KLINGMUELLER, V; STROHMEYER, G | 1 |
| BURCHALL, JJ; NIEDERMAN, RA; WOLIN, MJ | 1 |
| OLSON, JC; PUNCH, JD; SCALETTI, JV | 1 |
| Chalisova, NI; Penniiaĭnen, VA | 1 |
| Hövel, S; Klöppner, U; Röhm, KH; Sonawane, A; Völker, U | 1 |
| Chen, N; Li, B; Murphy, TH; Raymond, LA | 1 |
| Carrasco, N; De La Vieja, A; Ginter, CS | 1 |
| de Jong, AS; Glaudemans, DH; Melchers, WJ; van Kuppeveld, FJ; Willems, PH | 1 |
| Anderson, ME; Bhansali, VS; Cundari, TR; Dinescu, A; Luo, JL | 1 |
| Davies, MJ; Duja-Isac, CM; Edwards, RJ; Essin, KV; Hammes, A; Lippoldt, A; Morano, I; Neubauer, S; Nunez, DJ; Plehm, R; Spindler, M; Strömer, H; Thiel, C; Thierfelder, L; Wernicke, D; Wessel, N; Zacharias, U | 1 |
| Benevides, JM; Bondre, P; Duda, RL; Hendrix, RW; Thomas, GJ | 1 |
| Cukier, RI | 1 |
| Choi, YH; Erkelens, C; Hazekamp, A; Kim, HK; Lefeber, AW; Verpoorte, R | 1 |
| Hibino, H; Ishii, M; Kurachi, Y; Yamada, M | 1 |
| Gómez, P; Manzanares, J; Molina, JA; Oliva, JM; Ortiz, S; Pérez-Rial, S; Urigüen, L; Vargas, C; Villanueva, C | 1 |
| Adachi, M; Hirata, A; Mikami, B; Utsumi, S | 1 |
| Albo, F; Bernardi, G; Ferrari, F; Longone, P; Pascucci, T; Puglisi-Allegra, S; Spalloni, A; Zona, C | 1 |
| Guan, Z; McClerren, AL; Raetz, CR; Rudolph, J; Zhou, P | 1 |
| Brown, DE; Dooley, DM; Knowles, PF; Kurtis, CR; McPherson, MJ; Mure, M; Phillips, SE; Rogers, MS; Saysell, C; Tambyrajah, WS; Wilmot, CM | 1 |
| Arai, K; Fushinobu, S; Ishikura, Y; Kimber, MS; Pai, EF; Shigematsu-Iida, M; Shinoda, T; Taguchi, H; Tanaka, S; Yamada, T | 1 |
| Dalal, S; Starcevic, D; Sweasy, J | 1 |
| Eijsink, VG; Hoell, IA; Horn, SJ; Klemsdal, SS; Vaaje-Kolstad, G | 1 |
| Huang, HW; Inoue, M; Kataoka, K; Kitagawa, R; Naruse, D; Sakurai, T | 1 |
| Agarwal, R; Binz, T; Swaminathan, S | 1 |
| Bootim, N; Kamemura, A; Moriguchi, M; Tachiki, T; Wakayama, M; Yamagata, T; Yano, S; Yoshimune, K | 1 |
| Chuda, Y; Kobayashi, A; Matsuura-Endo, C; Mori, M; Noda, T; Ohara-Takada, A; Ono, H; Takigawa, S; Tsuda, S; Yada, H; Yamauchi, H; Yoshida, M | 1 |
| Estevez, A; Jeffery, D; Katz, BA; McGrath, M; Sampang, J; Shrader, W; Spencer, J; Sprengeler, PA; Springman, E; Tang, J; Williams, SR; Young, W; Yu, CL | 1 |
| Gillespie, D; Meissner, G; Wang, Y; Xu, L | 1 |
| Aktories, K; Vogelsgesang, M | 1 |
| Altman, A; Avramis, VI; Bostrom, B; Breneman, J; Fu, C; Gaynon, PS; Harris, RE; Jarrar, M; Periclou, AP; Steele, D; Stram, D; Trigg, M; Zipf, T | 1 |
| Andersen, JP; Anthonisen, AN; Clausen, JD; McIntosh, DB; Vilsen, B; Woolley, DG | 1 |
| Hashida, Y; Inouye, K; Kusano, M; Yasukawa, K | 1 |
| Altamirano, C; Becerra, S; Cairó, JJ; Gòdia, F; Illanes, A | 1 |
| Fernández, M; Zúñiga, M | 1 |
| Lapinski, PE; Perria, CL; Raghavan, M; Rajamanickam, V | 1 |
| Franklin, SJ; Harris, KL; Lim, S | 1 |
| Brown, LS; Fan, Y; Furutani, Y; Kandori, H; Shi, L; Sumii, M; Waschuk, SA | 1 |
| Cameron, CE; Korneeva, VS | 1 |
| Katayama, T; Kato, R; Nagae, M; Tsuchiya, A; Wakatsuki, S; Yamamoto, K | 1 |
| Collino, S; Delak, K; Evans, JS | 1 |
| Aniskina, AI; Chalisova, NI; Filippov, SV; Zakutskii, AN; Zezyulin, PN | 1 |
| Almeida, FC; Da Poian, AT; Juliano, L; Juliano, MA; Lima, CS; Sarzedas, CG; Valente, AP | 1 |
| Cane, DE; Christianson, DW; Jiang, J; Vedula, LS; Zakharian, T | 1 |
| Bae, E; Bingman, CA; Lee, JE; Phillips, GN; Raines, RT | 1 |
| Armentrout, PB; Heaton, AL; Ye, SJ | 1 |
| Boquet, P; Flatau, G; Ménétrey, J; Ménez, A; Stura, EA | 1 |
| Myler, PJ; Olafson, RW; Rosenzweig, D; Smith, D; Zilberstein, D | 1 |
| Kim, DE; Kim, HJ; Lee, JK; Oh, DK; Yeom, SJ | 1 |
| Bower, KS; Dougherty, DA; Lester, HA; Lummis, SC; Price, KL; Thompson, AJ | 1 |
| Akinshola, BE; Johnson, WD; Onaivi, ES; Parandaman, V; Taylor, RE | 1 |
| Boussuges, A; Risso, JJ; Rostain, JC; Vallée, N | 1 |
| Carr, D; Dallapozza, L; Earl, JW; Eslick, AE; Misra, A; Nath, CE | 1 |
| Ascenzi, P; Bolli, A; Colantonio, P; Leboffe, L; Luisi, G; Marino, M | 1 |
| CARTER, CE | 1 |
| Chalisova, NI; Zakutskii, AN | 1 |
| Acton, TB; Aramini, JM; Chen, CX; Fischer, M; Honig, B; Maglaqui, M; Montelione, GT; Nair, R; Nwosu, C; Owens, LA; Rossi, P; Rost, B; Xiao, R | 1 |
| Bennett, B; Holz, RC; Job, KM; Meng, L; Mitra, S | 1 |
| Holyavka, MG; Kovaleva, TA; Kozhedub, SV; Rezvan, SG | 1 |
| Chang, WC; Horng, JT; Hsu, JB; Hsu, PC; Huang, HD; Lee, TY; Shien, DM; Wang, TY | 1 |
| Fujimoto, K; Kinugawa, A; Nagahama, T; Narusuye, K; Takami, S | 1 |
| Garvín, A; Garza, S; Ibarz, A; Pagán, J | 1 |
| Frillingos, S; Karena, E | 1 |
| Bajrami, B; Lapierre, P; Shi, Y; Yao, X | 1 |
| Risso, JJ; Rostain, JC; Vallee, N | 2 |
| Brown, NG; Palzkill, T; Prasad, BV; Shanker, S | 1 |
| Estévez, A; Giménez, G; Lahnsteiner, F; Mente, E; Samaee, SM | 1 |
| Balland, A; Eakin, CM; Ketchem, RR; Treuheit, MJ; Valliere-Douglass, JF; Wallace, A; Wang, W | 1 |
| Culka, A; Edwards, HG; Jehlička, J | 1 |
| Ackermann, H; Blasel, S; Franz, K; Hattingen, E; Weidauer, S; Zanella, F | 1 |
| Massoura, AJ; Simms, J; Trim, JE; Wheatley, M; Wootten, DL | 1 |
| Przybylski, JL; Wetmore, SD | 1 |
| Carneiro, J; Henriques, AO; Moran, CP; Real, G; Santos, J; Serrano, M | 1 |
| Barnard, TJ; Bernstein, HD; Buchanan, SK; Dautin, N; Easley, NC; Gumbart, J; Kuszak, AJ; Noinaj, N; Peterson, JH; Tajkhorshid, E | 1 |
| Borovikov, YS; Karpicheva, OE; Redwood, CS; Rysev, NA | 1 |
| Niederweis, M; Song, H | 1 |
| Attarbaschi, A; Dworzak, MN; Haas, OA; Hochreiter, D; Hutter, C; Kasper, DC; Kornmüller, R; Mann, G; Pichler, H; Pötschger, U; Steiner, M | 1 |
| Nagahama, M; Oda, M; Sakurai, J; Takahashi, M; Tsuge, H | 1 |
| Fischer, S; Geeves, MA; Janco, M; Lehman, W; Li, XE; Marston, SB; Suphamungmee, W | 1 |
| Aparicio-Tejo, PM; Ariz, I; Asensio, AC; García-Mina, JM; Moran, JF; Zamarreño, AM | 1 |
| Becker, HD; Brayé, M; Drainas, D; Saad, NY; Stamatopoulou, V; Stathopoulos, C | 1 |
| Avila, C; Cánovas, FM; de la Torre, F; El-Azaz, J | 1 |
| Deighan, P; Jain, N; Javid, B; Pan, M; Pinkham, JT; Rubin, EJ; Sorrentino, F; Toosky, M; Zheng, W | 1 |
| Balercia, G; Buldreghini, E; Delli Muti, N; Lenzi, A; Tirabassi, G | 1 |
| Armentrout, PB; Rodgers, MT; Yang, B | 1 |
| Inokuchi, N; Itagaki, T; Kobayashi, H; Motoyoshi, N; Suzuki, M | 1 |
| Aza-Blanc, P; Osterman, AL; Ratnikov, B; Ronai, ZA; Scott, DA; Smith, JW | 1 |
| Kojo, S | 1 |
| Haribal, M; Jander, G | 1 |
| Boeckler, FM; Exner, TE; Lange, A; Zahn, S; Zimmermann, MO | 1 |
| Buttrick, GJ; Del Mar Mora-Santos, M; Hardwick, KG; Lancaster, TC; Meadows, JC; Messin, LJ; Millar, JBA; Sochaj, AM | 1 |
| Eoh, H; Gao, SJ; Jung, JU; Lee, JJ; Li, T; Lu, C; Ramos da Silva, S; Zhu, Y | 1 |
| Li, J; Li, Q; Li, W; Lu, D; Wang, D; Wang, J; Wang, Q; Wen, T; Wu, Y; Xie, J; Zhou, F; Zhou, H | 1 |
| Dai, G; Demura, M; Geng, X; Iwasa, T; Kamo, N; Kikukawa, T; Tamogami, J | 1 |
| Gao, W; Liu, H; Nie, Z; Rengel, Z; Wang, J; Zhao, P | 1 |
| Fernandez, C; Melander, O; Ottosson, F; Smith, E | 1 |
| Helmann, JD; Roistacher, DM; Zhao, H | 1 |
| Chen, H; Feng, Z; Leng, C; Liu, G; Lv, X; Qiao, Y; Sun, J; Zhang, Y | 1 |
| Garip, B; Kayir, H | 1 |
| Gerrits, J; Houwen, RHJ; Jans, JJM; Pras-Raves, ML; Rumping, L; Tang, YF; van Haaften, G; van Hasselt, PM; Verhoeven-Duif, NM; Willemsen, MA | 1 |
| Haring, L; Kangro, R; Koch, K; Leppik, L; Parksepp, M; Uppin, K; Vasar, E; Zilmer, M | 1 |
| Allain, FH; Cléry, A; Jorjani, H; Katsantoni, M; Krepl, M; Mittal, N; Moursy, A; Nguyen, CKX; Okoniewski, M; Sponer, J; Zavolan, M | 1 |
| Bielawski, JP; Cohen, A; Connors, J; Dunn, KA; Forbrigger, Z; Kulkarni, K; Langille, MGI; MacDonald, T; Penny, SL; Rahman, M; Stadnyk, AW; Van Limbergen, J | 1 |
| Du, D; Guo, F; Lin, H; Luo, C; Lv, S; Ye, F; Zhang, T; Zhang, Y; Zhou, L; Zhu, S | 1 |
| Bi, Y; Chen, G; Chen, L; Chen, Y; Dai, M; Deng, H; Du, R; Gao, Z; Hu, C; Hu, R; Huo, Y; Lai, S; Li, D; Li, M; Li, Q; Lin, H; Liu, C; Liu, R; Lu, J; Luo, Z; Mu, Y; Ning, G; Qin, G; Qin, Y; Shen, F; Shi, L; Su, Q; Tang, X; Wan, Q; Wang, G; Wang, J; Wang, S; Wang, T; Wang, W; Wang, X; Wang, Y; Wu, S; Xu, G; Xu, M; Xu, Y; Yan, L; Yang, T; Ye, Z; Yu, X; Zhang, D; Zhang, Y; Zhao, J; Zhao, X; Zhao, Z; Zheng, R | 1 |
| Chen, X; Ge, T; He, Z; Wang, J; Yuan, H; Zhang, L | 1 |
| Che, H; Duan, Q; Li, Q; Ren, J; Song, K; Wang, X; Yang, C; Yi, J; Yu, H | 1 |
| Guo, J; Han, D; Hu, Y; Li, M; Shi, L; Wei, J; Zhang, T | 1 |
| Oda, K; Wlodawer, A | 1 |
8 review(s) available for glutamic acid and asparagine
| Article | Year |
|---|---|
Amino acid composition of dentine in permanent human teeth.
Topics: Amino Acids; Asparagine; Aspartic Acid; Dentin; Glutamates; Glutamic Acid; Humans; Hydroxylysine; Lysine | 1992 |
Nonenzymatic deamidation of asparaginyl and glutaminyl residues in proteins.
Topics: Amides; Amino Acid Sequence; Animals; Asparagine; Aspartic Acid; Glutamates; Glutamic Acid; Glutamine; Humans; Molecular Sequence Data; Protein Processing, Post-Translational | 1991 |
Nitrogen catabolite repression in yeasts and filamentous fungi.
Topics: Amino Acids; Ammonia; Asparagine; Aspergillus nidulans; Biological Transport; Fungi; Genes, Fungal; Glutamates; Glutamic Acid; Glutamine; Membrane Transport Proteins; Neurospora crassa; Nitrogen; Proline; Saccharomyces cerevisiae; Yeasts | 1985 |
Membrane cholesterol, tumorigenesis, and the biochemical phenotype of neoplasia.
Topics: Acetates; Animals; Asparagine; Aspartic Acid; Biological Transport, Active; Cell Division; Cell Membrane Permeability; Cholesterol; Citric Acid Cycle; Electron Spin Resonance Spectroscopy; Glucose; Glutamates; Glutamic Acid; Glutamine; Lipid Bilayers; Liver Neoplasms, Experimental; Membrane Lipids; Mitochondria; Mitochondria, Liver; Models, Biological; Neoplasms; Oxygen Consumption; Phenotype; Purines; Pyrimidines; Pyruvates; Pyruvic Acid; Surface Properties | 1981 |
[Intrinsic glutaminergic systems and its negative regulation of melatonin synthesis in mammalian pineal glands].
Topics: Animals; Asparagine; Glutamic Acid; Melatonin; Pineal Gland; Signal Transduction | 2000 |
Metabolite and light regulation of metabolism in plants: lessons from the study of a single biochemical pathway.
Topics: Amino Acids, Dicarboxylic; Arabidopsis; Asparagine; Aspartate-Ammonia Ligase; Aspartic Acid; Carbon; Gene Expression Regulation, Plant; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Light; Nitrogen; Receptors, Glutamate | 2001 |
Amino acid catabolic pathways of lactic acid bacteria.
Topics: Alanine; Amino Acids; Amino Acids, Aromatic; Amino Acids, Branched-Chain; Asparagine; Aspartate Ammonia-Lyase; Aspartic Acid; Biodegradation, Environmental; Fermentation; Food Microbiology; Glutamate Decarboxylase; Glutamic Acid; Glutamine; Histidine; Lactic Acid; Lactobacillus; Proline | 2006 |
Overview of the Properties of Glutamic Peptidases That Are Present in Plant and Bacterial Pathogens and Play a Role in Celiac Disease and Cancer.
Topics: Asparagine; Bacteria; Celiac Disease; Glutamic Acid; Histidine; Humans; Neoplasms; Peptide Hydrolases | 2023 |
1 trial(s) available for glutamic acid and asparagine
| Article | Year |
|---|---|
Aspartame-sweetened beverage: effect on plasma amino acid concentrations in normal adults and adults heterozygous for phenylketonuria.
Topics: Adult; Amino Acids; Asparagine; Aspartame; Aspartic Acid; Beverages; Biological Transport; Dipeptides; Female; Glutamates; Glutamic Acid; Glutamine; Heterozygote; Humans; Kinetics; Male; Phenylalanine; Phenylketonurias; Tyrosine | 1987 |
280 other study(ies) available for glutamic acid and asparagine
| Article | Year |
|---|---|
Quantitative structure-activity relationships of the bitter thresholds of amino acids, peptides, and their derivatives.
Topics: Amino Acids; Humans; Mathematics; Peptides; Structure-Activity Relationship; Taste | 1987 |
Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters.
Topics: Amino Acid Sequence; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Animals; Anion Transport Proteins; Bacterial Proteins; Carrier Proteins; Cloning, Molecular; Escherichia coli Proteins; Female; Intestine, Small; Kinetics; Levodopa; Mice; Molecular Sequence Data; Oocytes; Phenylalanine; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tryptophan; Tyrosine; Xenopus laevis | 2001 |
Two alloalbumins with identical electrophoretic mobility are produced by differently charged amino acid substitutions.
Topics: Amino Acid Sequence; Asparagine; Aspartic Acid; Chromatography, High Pressure Liquid; Genetic Variation; Glutamates; Glutamic Acid; Humans; Isoelectric Focusing; Lysine; Molecular Sequence Data; Mutation; Serum Albumin | 1992 |
Inhibition of excitatory amino acid-stimulated phosphoinositide hydrolysis in rat hippocampus by L-aspartate-beta-hydroxamate.
Topics: Animals; Asparagine; Carbachol; Glutamates; Glutamic Acid; Hippocampus; Hydrolysis; Ibotenic Acid; In Vitro Techniques; Male; Phosphatidylinositols; Rats; Rats, Inbred Strains | 1992 |
Structure and function of alternative proton-relay mutants of dihydrofolate reductase.
Topics: Asparagine; Binding Sites; Crystallography; Escherichia coli; Glutamates; Glutamic Acid; Humans; Hydrogen-Ion Concentration; Kinetics; Methotrexate; Mutagenesis, Site-Directed; Protons; Pteridines; Spectrophotometry, Ultraviolet; Tetrahydrofolate Dehydrogenase | 1992 |
Mechanistic consequences of mutation of the active site nucleophile Glu 358 in Agrobacterium beta-glucosidase.
Topics: Asparagine; Aspartic Acid; beta-Glucosidase; Binding Sites; Deuterium; Drug Stability; Glucosides; Glutamates; Glutamic Acid; Glutamine; Glycosylation; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Mutagenesis, Site-Directed; Protein Conformation; Rhizobium; Structure-Activity Relationship | 1992 |
Site-directed mutagenesis of conserved residues of Clostridium thermocellum endoglucanase CelC.
Topics: Amino Acid Sequence; Arginine; Asparagine; Cellulase; Clostridium; Glutamates; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Kinetics; Mutagenesis, Site-Directed; Recombinant Proteins; Restriction Mapping | 1992 |
Control by asparagine residues of calcium permeability and magnesium blockade in the NMDA receptor.
Topics: Amino Acid Sequence; Animals; Asparagine; Binding Sites; Calcium; Cell Line; Electric Conductivity; Glutamates; Glutamic Acid; Ion Channels; Magnesium; Mice; Molecular Sequence Data; Mutagenesis; Oocytes; Permeability; Rats; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship; Transfection; Xenopus | 1992 |
Characterization of glutamate uptake systems in astrocyte primary cultures from rat brain.
Topics: Animals; Asparagine; Aspartic Acid; Astrocytes; Biological Transport; Cells, Cultured; Chlorides; Glutamates; Glutamic Acid; Ion Channels; Kinetics; Potassium; Quisqualic Acid; Rats; Sodium | 1991 |
Purification and functional characterization of the Glu-tRNA(Gln) amidotransferase from Chlamydomonas reinhardtii.
Topics: Adenosine Triphosphate; Ammonia; Asparagine; Azo Compounds; Binding Sites; Chlamydomonas; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Glutamates; Glutamic Acid; Glutamine; Magnesium; Molecular Weight; Nitrogenous Group Transferases; Norleucine; Phosphorylation; Protein Denaturation; RNA, Transfer, Amino Acyl; Spectrophotometry; Substrate Specificity; Transferases | 1990 |
Spinal cord ischemia-induced elevation of amino acids: extracellular measurement with microdialysis.
Topics: Amino Acids; Animals; Asparagine; Chromatography, High Pressure Liquid; Dialysis; Extracellular Space; Glutamates; Glutamic Acid; Glycine; Ischemia; Kinetics; Rabbits; Spinal Cord; Taurine; Valine | 1990 |
Non-essential nitrogen and protein utilization in the growing rat.
Topics: Amino Acids, Essential; Animal Nutritional Physiological Phenomena; Animals; Asparagine; Diet; Glutamates; Glutamic Acid; Male; Nitrogen; Proline; Rats; Rats, Inbred Strains | 1990 |
Determinants of visual pigment absorbance: identification of the retinylidene Schiff's base counterion in bovine rhodopsin.
Topics: Animals; Asparagine; Aspartic Acid; Cattle; Glutamates; Glutamic Acid; Glutamine; Kinetics; Membranes; Models, Molecular; Mutagenesis, Site-Directed; Plasmids; Protein Conformation; Recombinant Proteins; Retinaldehyde; Rhodopsin; Schiff Bases; Spectrophotometry | 1990 |
Free amino acid analysis of guinea pig perilymph: a possible clinical assay for the PLF enigma?
Topics: Amino Acids; Animals; Arginine; Asparagine; Biomarkers; Chromatography; Chromatography, High Pressure Liquid; Fistula; Glutamates; Glutamic Acid; Glutamine; Guinea Pigs; Histidine; Isoleucine; Labyrinth Diseases; Leucine; Lysine; Perilymph; Phenylalanine; Spectrometry, Fluorescence; Threonine; Tyrosine; Valine | 1990 |
Effects of buried ionizable amino acids on the reduction potential of recombinant myoglobin.
Topics: Asparagine; Aspartic Acid; Glutamates; Glutamic Acid; Heme; Humans; Mutation; Myoglobin; Oxidation-Reduction; Protein Conformation; Recombinant Proteins; Thermodynamics; Valine | 1989 |
Effect of impact trauma on neurotransmitter and nonneurotransmitter amino acids in rat spinal cord.
Topics: Alanine; Amino Acids; Animals; Asparagine; Aspartic Acid; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Glycine; Kinetics; Laminectomy; Male; N-Methylaspartate; Neurotransmitter Agents; Rats; Serine; Spinal Cord; Spinal Cord Injuries; Taurine; Threonine | 1989 |
Changes in stability and allosteric properties of aspartate transcarbamoylase resulting from amino acid substitutions in the zinc-binding domain of the regulatory chains.
Topics: Allosteric Regulation; Amino Acids; Asparagine; Aspartate Carbamoyltransferase; Binding Sites; Catalysis; Cysteine; Drug Stability; Escherichia coli; Glutamates; Glutamic Acid; Macromolecular Substances; Mutation; Protein Conformation; Salmonella typhimurium; Structure-Activity Relationship; Zinc | 1989 |
Effect of repeated ingestion of aspartame-sweetened beverage on plasma amino acid, blood methanol, and blood formate concentrations in normal adults.
Topics: Adult; Amino Acids; Asparagine; Aspartame; Aspartic Acid; Beverages; Dipeptides; Female; Formates; Glutamates; Glutamic Acid; Glutamine; Humans; Male; Methanol; Phenylalanine; Tryptophan; Tyrosine | 1989 |
Functional consequences of glutamate, aspartate, glutamine, and asparagine mutations in the stalk sector of the Ca2+-ATPase of sarcoplasmic reticulum.
Topics: Amino Acid Sequence; Animals; Asparagine; Aspartic Acid; Biological Transport; Calcium; Calcium-Transporting ATPases; Cell Line; Cloning, Molecular; Glutamates; Glutamic Acid; Glutamine; Immunoblotting; Microsomes; Molecular Sequence Data; Muscles; Mutation; Phosphorylation; Rabbits; Recombinant Fusion Proteins; Sarcoplasmic Reticulum; Transfection | 1989 |
Bacteriorhodopsin mutants of Halobacterium sp. GRB. II. Characterization of mutants.
Topics: Amino Acid Sequence; Asparagine; Aspartic Acid; Bacteriorhodopsins; Base Sequence; Cloning, Molecular; Cysteine; Genes, Bacterial; Glutamates; Glutamic Acid; Glycine; Halobacterium; Molecular Sequence Data; Mutation; Protein Conformation; Tryptophan; Tyrosine | 1989 |
Substitution of membrane-embedded aspartic acids in bacteriorhodopsin causes specific changes in different steps of the photochemical cycle.
Topics: Alanine; Amino Acid Sequence; Asparagine; Aspartic Acid; Bacteriorhodopsins; Cell Membrane; Glutamates; Glutamic Acid; Hydrogen-Ion Concentration; Kinetics; Lipid Bilayers; Molecular Sequence Data; Mutation; Photochemistry | 1989 |
Prevention of methotrexate cytotoxicity by asparaginase inhibition of methotrexate polyglutamate formation.
Topics: Animals; Asparaginase; Asparagine; Biological Transport; Cell Survival; DNA Replication; Glutamates; Glutamic Acid; Glutamine; Kinetics; Leukemia L5178; Leukemia, Experimental; Methotrexate; Mice; Peptides; Polyglutamic Acid | 1985 |
The effect of transport system A and N amino acids and of nerve and epidermal growth factors on the induction of ornithine decarboxylase activity.
Topics: Amino Acids; Aminoisobutyric Acids; Asparagine; Cells, Cultured; Enzyme Induction; Epidermal Growth Factor; Glutamates; Glutamic Acid; Nerve Growth Factors; Neuroblastoma; Ornithine Decarboxylase; Valine | 1985 |
Separation of amino acid and amide nitrogen from plant extracts for 15N analysis.
Topics: Amides; Amino Acids; Ammonia; Asparagine; Aspartic Acid; Chromatography, Ion Exchange; Fabaceae; Glutamates; Glutamic Acid; Glutamine; Nitrogen; Nitrogen Isotopes; Plants; Plants, Medicinal | 1986 |
Post-translational modifications of chloroperoxidase from Caldariomyces fumago.
Topics: Amino Acid Sequence; Amino Acids; Asparagine; Chloride Peroxidase; Chromatography, High Pressure Liquid; Glutamates; Glutamic Acid; Glutamine; Glycosylation; Isoenzymes; Mitosporic Fungi; Peptide Fragments; Peroxidases; Protein Conformation; Protein Processing, Post-Translational; Protein Sorting Signals | 1987 |
[Amino acid neurotransmitters].
Topics: Animals; Asparagine; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Receptors, GABA-A; Synaptic Transmission | 1987 |
Conserved aspartic acid residues 79 and 113 of the beta-adrenergic receptor have different roles in receptor function.
Topics: Animals; Asparagine; Aspartic Acid; Cell Membrane; Epinephrine; Glutamates; Glutamic Acid; Isoproterenol; Kinetics; L Cells; Mice; Mutation; Receptors, Adrenergic, beta; Structure-Activity Relationship | 1988 |
Ca2+-dependent activation of the malate-aspartate shuttle by norepinephrine and vasopressin in perfused rat liver.
Topics: Alanine; Animals; Asparagine; Aspartic Acid; Calcimycin; Calcium; Ethanol; Glucose; Glutamates; Glutamic Acid; Ketoglutaric Acids; Liver; Malates; Male; Norepinephrine; Perfusion; Rats; Rats, Inbred Strains; Sorbitol; Vasopressins | 1988 |
Influence of total nitrogen, asparagine, and glutamine on MCA tumor growth in the Fischer 344 rat.
Topics: Amino Acids; Animals; Asparagine; Aspartic Acid; Body Weight; Glutamates; Glutamic Acid; Glutamine; Male; Nitrogen; Organ Size; Parenteral Nutrition, Total; Rats; Rats, Inbred F344; Sarcoma, Experimental | 1988 |
[Pathways of the synthesis of glutamic acid by cephalosporin C-producing Acremonium chrysogenum].
Topics: Acremonium; Asparagine; Cephalosporins; Culture Media; Glutamate Dehydrogenase; Glutamate-Ammonia Ligase; Glutamates; Glutamic Acid; Methionine; Nitrogen | 1988 |
Huntington's disease. Glutamate and aspartate metabolism in blood platelets.
Topics: Adult; Asparagine; Aspartic Acid; Blood Platelets; Female; Glutamates; Glutamic Acid; Glutamine; Humans; Huntington Disease; Kinetics; Male; Middle Aged | 1982 |
Release of endogenous and accumulated exogenous amino acids from slices of normal and climbing fibre-deprived rat cerebellar slices.
Topics: Amino Acids; Animals; Asparagine; Aspartic Acid; Cerebellum; Corpus Striatum; Glutamates; Glutamic Acid; Magnesium; Olivary Nucleus; Pyridines; Rats | 1983 |
Successful long-term use of a plasmapheresis reactor system in dogs with lymphoma.
Topics: Animals; Asparagine; Dog Diseases; Dogs; Glutamates; Glutamic Acid; Glutamine; Kinetics; Lymphoma; Plasmapheresis | 1983 |
Mutagenesis of the conserved aspartic acid 443, glutamic acid 478, asparagine 494, and aspartic acid 498 residues in the ribonuclease H domain of p66/p51 human immunodeficiency virus type I reverse transcriptase. Expression and biochemical analysis.
Topics: Amino Acid Sequence; Asparagine; Aspartic Acid; Base Sequence; Conserved Sequence; DNA Mutational Analysis; Enzyme Stability; Escherichia coli; Glutamates; Glutamic Acid; HIV Reverse Transcriptase; HIV-1; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Conformation; Protein Denaturation; Ribonuclease H; RNA-Directed DNA Polymerase; Structure-Activity Relationship | 1994 |
Yeast N-terminal amidase. A new enzyme and component of the N-end rule pathway.
Topics: Acyltransferases; Amidohydrolases; Amino Acid Sequence; Amino Acids; Aminoacyltransferases; Asparagine; Aspartic Acid; Base Sequence; Carbohydrate Sequence; Cloning, Molecular; Codon; Fungal Proteins; Genes, Fungal; Glutamic Acid; Glutamine; Half-Life; Ligases; Models, Molecular; Molecular Sequence Data; Multienzyme Complexes; Promoter Regions, Genetic; Protein Processing, Post-Translational; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Ubiquitin-Protein Ligases | 1995 |
Paraquat--a superoxide generator--kills neurons in the rat spinal cord.
Topics: Amino Acids; Animals; Asparagine; Aspartic Acid; Cell Death; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Male; Microdialysis; Neurons; Neurotoxins; Paraquat; Rats; Rats, Sprague-Dawley; Spinal Cord; Superoxides; Synapses; Time Factors | 1995 |
Site-specificity of the second-site suppressor mutation of the Asp-285-->Asn mutant of metal-tetracycline/H+ antiporter of Escherichia coli and the effects of amino acid substitutions at the first and second sites.
Topics: Amino Acid Sequence; Antiporters; Asparagine; Aspartic Acid; Bacterial Proteins; Biological Transport; Escherichia coli; Glutamic Acid; Molecular Sequence Data; Mutagenesis, Site-Directed; Structure-Activity Relationship; Suppression, Genetic; Tetracycline | 1995 |
(2S,3S,4R)-2-(carboxycyclopropyl)glycine, a potent and competitive inhibitor of both glial and neuronal uptake of glutamate.
Topics: Amino Acids, Dicarboxylic; Animals; Anti-Bacterial Agents; Asparagine; Aspartic Acid; Astrocytes; Cell Membrane; Cells, Cultured; Depression, Chemical; Female; Glutamates; Glutamic Acid; Hippocampus; Kinetics; Neuroglia; Neurons; Pregnancy; Rats; Rats, Wistar; Stereoisomerism; Synaptosomes | 1993 |
Protonation states of membrane-embedded carboxylic acid groups in rhodopsin and metarhodopsin II: a Fourier-transform infrared spectroscopy study of site-directed mutants.
Topics: Amino Acid Sequence; Animals; Asparagine; Aspartic Acid; Cell Line; Glutamates; Glutamic Acid; Glutamine; Kinetics; Light; Mutagenesis, Site-Directed; Protein Conformation; Recombinant Proteins; Retinaldehyde; Rhodopsin; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Time Factors; Transfection | 1993 |
Second-site mutation of Ala-220 to Glu or Asp suppresses the mutation of Asp-285 to Asn in the transposon Tn10-encoded metal-tetracycline/H+ antiporter of Escherichia coli.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Antiporters; Asparagine; Aspartic Acid; Bacterial Proteins; Base Sequence; Biological Transport; DNA Transposable Elements; DNA, Bacterial; Escherichia coli; Glutamates; Glutamic Acid; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Plasmids; Protein Structure, Secondary; Repressor Proteins; Suppression, Genetic; Tetracycline | 1993 |
Three new mutations of thyroid hormone receptor-beta associated with resistance to thyroid hormone.
Topics: Adolescent; Adult; Amino Acid Sequence; Asparagine; Aspartic Acid; Base Sequence; Drug Resistance; Female; Glutamates; Glutamic Acid; Glutamine; Humans; Lysine; Male; Molecular Sequence Data; Point Mutation; Receptors, Thyroid Hormone; Sicily; Syndrome; Thyroid Hormones | 1994 |
Short-term starvation alters the free amino acid content of the human intestinal mucosa.
Topics: Adult; Amino Acids; Amino Acids, Branched-Chain; Asparagine; Colon; Duodenum; Food; Glutamates; Glutamic Acid; Glutamine; Histidine; Humans; Intestinal Mucosa; Intestine, Large; Male; Starvation; Threonine; Time Factors | 1994 |
A patch clamp study of excitatory amino acid effects on cortical astrocyte subtypes in culture.
Topics: Action Potentials; Animals; Asparagine; Astrocytes; Biological Transport, Active; Cells, Cultured; Cerebral Cortex; Glutamates; Glutamic Acid; Kainic Acid; Membrane Potentials; Rats; Receptors, Amino Acid | 1993 |
Two transthyretin mutations (glu42gly, his90asn) in an Italian family with amyloidosis.
Topics: Adult; Amyloid Neuropathies; Asparagine; Base Sequence; DNA Mutational Analysis; Female; Glutamic Acid; Glycine; Histidine; Humans; Male; Molecular Sequence Data; Pedigree; Point Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Prealbumin | 1994 |
L-glutamate uptake inhibitors may stimulate phosphoinositide hydrolysis in baby hamster kidney cells expressing mGluR1a via heteroexchange with L-glutamate without direct activation of mGluR1a.
Topics: Alanine Transaminase; Animals; Asparagine; Aspartic Acid; Cell Line; Cell Membrane; Cricetinae; Cycloleucine; Cysteine; Dicarboxylic Acids; Excitatory Amino Acid Antagonists; Glutamate Decarboxylase; Glutamic Acid; Hydrolysis; Kidney; N-Methylaspartate; Phosphatidylinositols; Pyrrolidines; Receptors, Metabotropic Glutamate | 1994 |
A single aspartate residue is involved in both intrinsic gating and blockage by Mg2+ of the inward rectifier, IRK1.
Topics: Amino Acid Sequence; Animals; Asparagine; Aspartic Acid; Base Sequence; Binding Sites; Cell Membrane; Conserved Sequence; Glutamic Acid; Ion Channel Gating; Leukemia, Erythroblastic, Acute; Magnesium; Mice; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Point Mutation; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Structure, Secondary; Transfection; Tumor Cells, Cultured | 1994 |
Taurine, amino acid transmitters, and related molecules in the retina of the Australian lungfish Neoceratodus forsteri: a light-microscopic immunocytochemical and electron-microscopic study.
Topics: Animals; Arginine; Asparagine; Fishes; gamma-Aminobutyric Acid; Ganglia, Sensory; Glutamic Acid; Glutamine; Immunohistochemistry; Microglia; Microscopy, Electron; Neurotransmitter Agents; Nitric Oxide; Photoreceptor Cells; Retina; Taurine | 1994 |
An evaluation of the role of extracellular amino acids in the delayed neurodegeneration induced by quinolinic acid in the rat striatum.
Topics: Amino Acids; Animals; Asparagine; Aspartic Acid; Corpus Striatum; Dialysis; Dizocilpine Maleate; Glutamates; Glutamic Acid; Glycine; Male; Microinjections; Nerve Degeneration; Niacin; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Serine; Threonine | 1993 |
Subunit-specific block of cloned NMDA receptors by argiotoxin636.
Topics: Amino Acid Sequence; Animals; Asparagine; Cloning, Molecular; Female; Glutamates; Glutamic Acid; Glutamine; Glycine; Indoleacetic Acids; Kinetics; Macromolecular Substances; Molecular Sequence Data; Mutagenesis, Site-Directed; Oocytes; Phenylacetates; Polyamines; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Spider Venoms; Xenopus laevis | 1993 |
Clarification of the pH-dependent kinetic behaviour of papain by using reactivity probes and analysis of alkylation and catalysed acylation reactions in terms of multihydronic state models: implications for electrostatics calculations and interpretation o
Topics: Acylation; Alkylation; Asparagine; Aspartic Acid; Catalysis; Electrochemistry; Glutamates; Glutamic Acid; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Mutagenesis, Site-Directed; Papain; Substrate Specificity | 1993 |
Changes in intracellular concentration of amino acids in human saphenous vein during preparation for coronary artery bypass grafting.
Topics: Adenosine Triphosphate; Amino Acids; Asparagine; Biological Transport; Chromatography, High Pressure Liquid; Coronary Artery Bypass; Glutamic Acid; Glutamine; Humans; Intracellular Fluid; Saphenous Vein; Taurine | 1995 |
Active-site topologies of human CYP2D6 and its aspartate-301 --> glutamate, asparagine, and glycine mutants.
Topics: Asparagine; Aspartic Acid; Binding Sites; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme System; Electrochemistry; Glutamic Acid; Glycine; Humans; Hydrazines; Imines; Mixed Function Oxygenases; Models, Molecular; Molecular Structure; Mutation; Protoporphyrins; Saccharomyces cerevisiae; Structure-Activity Relationship | 1996 |
Changes in the intracellular free amino acid pool in human saphenous vein tissue culture.
Topics: Aged; Alanine; Amino Acids; Asparagine; Aspartic Acid; Culture Techniques; Cytosol; Glutamic Acid; Glutamine; Glycine; Humans; Middle Aged; Proline; Saphenous Vein; Serine; Taurine | 1996 |
A glutamate/glutamine/aspartate/asparagine transport operon in Rhodobacter capsulatus.
Topics: Amino Acid Sequence; Amino Acid Transport Systems; Asparagine; Aspartic Acid; Biological Transport; Carrier Proteins; Chromosome Mapping; Cloning, Molecular; Glutamic Acid; Glutamine; Molecular Sequence Data; Operon; Rhodobacter capsulatus; Sequence Homology, Amino Acid | 1996 |
Neurotransmitter amino acids in cerebrospinal fluid of patients with Parkinson's disease.
Topics: Aged; Amino Acids; Asparagine; Aspartic Acid; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glycine; Humans; Male; Middle Aged; Neurotransmitter Agents; Parkinson Disease | 1996 |
Monitoring of asparaginase activity and asparagine levels in children on different asparaginase preparations.
Topics: Adolescent; Antineoplastic Agents; Asparaginase; Asparagine; Aspartic Acid; Child; Child, Preschool; Glutamic Acid; Glutamine; Humans; Infant; Infant, Newborn; Lymphoma, Non-Hodgkin; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1996 |
Substrate binding mechanism of Glu180-->Gln, Asp176-->Asn, and wild-type glucoamylases from Aspergillus niger.
Topics: Asparagine; Aspartic Acid; Aspergillus niger; Glucan 1,4-alpha-Glucosidase; Glutamic Acid; Glutamine; Kinetics; Models, Chemical; Point Mutation; Protein Binding; Thermodynamics | 1996 |
Intracellular acidification of the leech giant glial cell evoked by glutamate and aspartate.
Topics: 2-Aminoadipic Acid; 6-Cyano-7-nitroquinoxaline-2,3-dione; Acids; Animals; Antineoplastic Agents; Asparagine; Aspartic Acid; Calcium; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Ganglia, Invertebrate; Glutamic Acid; Hydrogen-Ion Concentration; Kainic Acid; Leeches; Membrane Potentials; Neuroglia; Patch-Clamp Techniques; Sodium | 1997 |
Substrate recognition of isocitrate dehydrogenase and 3-isopropylmalate dehydrogenase from Thermus thermophilus HB8.
Topics: 3-Isopropylmalate Dehydrogenase; Alcohol Oxidoreductases; Amino Acid Sequence; Asparagine; Aspartic Acid; Binding Sites; Glutamic Acid; Isocitrate Dehydrogenase; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Serine; Substrate Specificity; Thermus thermophilus | 1997 |
Isolation and characterization of Rhizobium etli mutants altered in degradation of asparagine.
Topics: Asparaginase; Asparagine; Aspartate Ammonia-Lyase; Aspartic Acid; Cloning, Molecular; Enzyme Stability; Genes, Bacterial; Genetic Complementation Test; Glutamic Acid; Glutamine; Isoenzymes; Mutation; Nitrogenase; Rhizobium; Temperature | 1997 |
Effect of polar side chains at position 172 on thermal stability of 3-isopropylmalate dehydrogenase from Thermus thermophilus.
Topics: 3-Isopropylmalate Dehydrogenase; Alanine; Alcohol Oxidoreductases; Asparagine; Enzyme Stability; Glutamic Acid; Glutamine; Heating; Molecular Structure; Mutagenesis, Site-Directed; Protein Conformation; Structure-Activity Relationship; Thermus thermophilus | 1997 |
Effects of two hypertrophic cardiomyopathy mutations in alpha-tropomyosin, Asp175Asn and Glu180Gly, on Ca2+ regulation of thin filament motility.
Topics: Actins; Animals; Asparagine; Aspartic Acid; Cardiomyopathy, Hypertrophic; Glutamic Acid; Glycine; Muscle, Skeletal; Mutation; Myosin Subfragments; Phalloidine; Rabbits; Rhodamines; Tropomyosin; Troponin | 1997 |
Glutamine homologues and derivatives: a limiting factor in current artificial nutrition?
Topics: Arginine; Asparagine; Aspartic Acid; Evaluation Studies as Topic; Glutamic Acid; Glutamine; Humans; Oxaloacetates; Parenteral Nutrition, Total | 1997 |
Heterozygous lipoprotein lipase deficiency: frequency in the general population, effect on plasma lipid levels, and risk of ischemic heart disease.
Topics: Adult; Aged; Aged, 80 and over; Apolipoprotein A-I; Asparagine; Cholesterol, HDL; Coronary Artery Disease; Female; Gene Frequency; Glutamic Acid; Glycine; Heterozygote; Humans; Isoleucine; Lipids; Lipoprotein Lipase; Male; Middle Aged; Phenotype; Point Mutation; Risk Factors; Serine; Triglycerides | 1997 |
Evaluation of the role of specific acidic amino acid residues in electron transfer between the flavodoxin and cytochrome c3 from Desulfovibrio vulgaris.
Topics: Amino Acids, Dicarboxylic; Asparagine; Aspartic Acid; Cytochrome c Group; Desulfovibrio vulgaris; Electrochemistry; Electron Transport; Flavodoxin; Gene Expression Regulation, Bacterial; Glutamic Acid; Glutamine; Models, Molecular; Mutagenesis, Site-Directed; Osmolar Concentration | 1997 |
Neurotransmitters in cerebrospinal fluid reflect pathological activity.
Topics: Adult; Aged; Asparagine; Aspartic Acid; Blood-Brain Barrier; Central Nervous System Diseases; Female; Glutamic Acid; Glutamine; Glycine; Humans; L-Lactate Dehydrogenase; Male; Middle Aged; Neurotransmitter Agents; Serine; Taurine | 1997 |
Effects of mutation of residue I67 on redox-linked protonation processes in yeast cytochrome c oxidase.
Topics: Asparagine; Electron Transport Complex IV; Glutamic Acid; Heme; Hydrogen-Ion Concentration; Isoleucine; Kinetics; Macromolecular Substances; Models, Molecular; Oxidation-Reduction; Point Mutation; Potentiometry; Protein Conformation; Recombinant Proteins; Saccharomyces cerevisiae | 1998 |
Compensation for D-glutamate auxotrophy of Escherichia coli WM335 by D-amino acid aminotransferase gene and regulation of murI expression.
Topics: Alanine Transaminase; Amino Acid Isomerases; Asparagine; Culture Media; D-Alanine Transaminase; Escherichia coli; Gene Expression; Glutamic Acid; Lysine; Mutagenesis, Site-Directed | 1998 |
Involvement of glutamic acid residue at position 7 in the formation of the intramolecular disulfide bond of Escherichia coli heat-stable enterotoxin Ip in vivo.
Topics: Amino Acid Sequence; Asparagine; Bacterial Toxins; Disulfides; Enterotoxins; Escherichia coli; Escherichia coli Proteins; Glutamic Acid; Molecular Sequence Data; Mutagenesis, Site-Directed; Proline; Recombinant Fusion Proteins | 1998 |
Involvement of glutamic acid 278 in the redox reaction of the cytochrome c oxidase from Paracoccus denitrificans investigated by FTIR spectroscopy.
Topics: Asparagine; Aspartic Acid; Deuterium Oxide; Electron Transport Complex IV; Glutamic Acid; Glutamine; Hydrogen-Ion Concentration; Mutagenesis, Site-Directed; Oxidation-Reduction; Paracoccus denitrificans; Serine; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared | 1998 |
Spectroscopic evidence for interaction between transmembrane helices 3 and 5 in rhodopsin.
Topics: Alanine; Amino Acid Substitution; Animals; Asparagine; Cattle; Glutamic Acid; Glutamine; Histidine; Membrane Proteins; Mutagenesis, Site-Directed; Phenylalanine; Photochemistry; Protein Structure, Secondary; Rhodopsin; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Transducin | 1998 |
The separate effects of E60Q in Lactobacillus casei thymidylate synthase delineate between mechanisms for formation of intermediates in catalysis.
Topics: Amino Acid Substitution; Asparagine; Binding Sites; Catalysis; Crystallography, X-Ray; Deoxyuracil Nucleotides; Folic Acid; Glutamic Acid; Glutamine; Lacticaseibacillus casei; Mutation; Nucleotides; Protein Binding; Protein Conformation; Pyrimidines; Quinazolines; Structure-Activity Relationship; Substrate Specificity; Thymidylate Synthase | 1998 |
Glu78, from the conserved PEWY sequence of subunit IV, has a key function in cytochrome b6f turnover.
Topics: Amino Acid Sequence; Animals; Asparagine; Aspartic Acid; Chlamydomonas reinhardtii; Chloroplasts; Conserved Sequence; Cytochrome b Group; Cytochrome b6f Complex; Electron Transport; Glutamic Acid; Glutamine; Kinetics; Leucine; Lysine; Mutagenesis, Site-Directed; Oxidation-Reduction; Peptide Fragments; Transformation, Genetic | 1998 |
Preserved catalytic activity in an engineered ribonucleotide reductase R2 protein with a nonphysiological radical transfer pathway. The importance of hydrogen bond connections between the participating residues.
Topics: Amino Acid Substitution; Asparagine; Aspartic Acid; Catalysis; Escherichia coli; Free Radicals; Glutamic Acid; Hydrogen Bonding; Iron; Protein Binding; Protein Engineering; Ribonucleotide Reductases; Tyrosine | 1998 |
Altering the purine specificity of hypoxanthine-guanine-xanthine phosphoribosyltransferase from Tritrichomonas foetus by structure-based point mutations in the enzyme protein.
Topics: Adenine Phosphoribosyltransferase; Amino Acid Substitution; Animals; Arginine; Asparagine; Aspartic Acid; Binding Sites; Catalysis; Enzyme Activation; Glutamic Acid; Guanine; Guanosine Monophosphate; Humans; Hypoxanthine Phosphoribosyltransferase; Isoleucine; Lysine; Mutagenesis, Site-Directed; Phenylalanine; Point Mutation; Purines; Ribonucleotides; Serine; Structure-Activity Relationship; Substrate Specificity; Tritrichomonas foetus; Tyrosine; Xanthine | 1998 |
Effect of H helix destabilizing mutations on the kinetic and equilibrium folding of apomyoglobin.
Topics: Apoproteins; Asparagine; Circular Dichroism; Fluorescence Polarization; Glutamic Acid; Glycine; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Mutagenesis; Myoglobin; Protein Conformation; Protein Folding; Urea | 1999 |
Calcium binding to the class I alpha-1,2-mannosidase from Saccharomyces cerevisiae occurs outside the EF hand motif.
Topics: Asparagine; Aspartic Acid; Binding Sites; Calcium; Calcium-Binding Proteins; Catalysis; Enzyme Stability; Glutamic Acid; Glutamine; Hot Temperature; Kinetics; Mannosidases; Mutagenesis, Site-Directed; Peptide Fragments; Recombinant Proteins; Saccharomyces cerevisiae | 1999 |
Histidine77, glutamic acid81, glutamic acid123, threonine126, asparagine194, and tryptophan197 of the human emopamil binding protein are required for in vivo sterol delta 8-delta 7 isomerization.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Amino Acids; Asparagine; Carrier Proteins; Cell Membrane; Glutamic Acid; Histidine; Humans; Isoenzymes; Molecular Sequence Data; Mutagenesis, Site-Directed; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Peptide Fragments; Piperidines; Saccharomyces cerevisiae; Steroid Isomerases; Threonine; Tryptophan | 1999 |
Is glutamine a pretender to the throne?
Topics: Arginine; Asparagine; Aspartic Acid; Dipeptides; Glutamic Acid; Glutamine; Humans; Parenteral Nutrition, Total | 1999 |
Thiamin-binding protein from sunflower seeds.
Topics: Asparagine; Aspartic Acid; Carrier Proteins; Chromatography, Gel; Glutamic Acid; Glutamine; Helianthus; Hydrogen-Ion Concentration; Molecular Weight; Seeds; Thiamine | 1998 |
The contribution of acidic residues to the conformational stability of common-type acylphosphatase.
Topics: Acid Anhydride Hydrolases; Acylphosphatase; Amino Acid Substitution; Asparagine; Aspartic Acid; Enzyme Stability; Glutamic Acid; Glutamine; Humans; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation; Recombinant Fusion Proteins; Substrate Specificity | 1999 |
Mutations at four active site residues of biotin carboxylase abolish substrate-induced synergism by biotin.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Arginine; Asparagine; Binding Sites; Biotin; Carbon-Nitrogen Ligases; Drug Synergism; Escherichia coli; Glutamic Acid; Histidine; Kinetics; Magnesium; Mutagenesis, Site-Directed; Peptides; Plasmids; Substrate Specificity | 1999 |
Crystal structure determination of cholesterol oxidase from Streptomyces and structural characterization of key active site mutants.
Topics: Asparagine; Binding Sites; Cholesterol Oxidase; Crystallography, X-Ray; Flavin-Adenine Dinucleotide; Glutamic Acid; Glutamine; Histidine; Models, Molecular; Mutagenesis, Site-Directed; Streptomyces; Structure-Activity Relationship; Substrate Specificity; Water | 1999 |
Identification of metal ligands in the Clostridium histolyticum ColH collagenase.
Topics: Amino Acid Sequence; Asparagine; Bacterial Proteins; Base Sequence; Catalytic Domain; Clostridium; Collagenases; Glutamic Acid; Histidine; Kinetics; Ligands; Models, Chemical; Molecular Sequence Data; Mutagenesis, Site-Directed; Zinc | 1999 |
Measurement of urinary amino acids using high-performance liquid chromatography equipped with a strong cation exchange resin pre-column.
Topics: Amino Acids; Asparagine; Aspartic Acid; Chromatography, High Pressure Liquid; Glutamic Acid; Glutamine; Humans; Reproducibility of Results | 1999 |
An unexpected role for the active site base in cofactor orientation and flexibility in the copper amine oxidase from Hansenula polymorpha.
Topics: Amine Oxidase (Copper-Containing); Ammonia; Asparagine; Aspartic Acid; Binding Sites; Carbon; Deuterium; Enzyme Activation; Glutamic Acid; Hydrogen; Methylamines; Mutagenesis, Site-Directed; Oxygen; Pichia; Schiff Bases; Solvents; Spectrophotometry, Ultraviolet; Spectrum Analysis, Raman; Substrate Specificity; Viscosity | 1999 |
The active site base controls cofactor reactivity in Escherichia coli amine oxidase: x-ray crystallographic studies with mutational variants.
Topics: Amine Oxidase (Copper-Containing); Asparagine; Aspartic Acid; Binding Sites; Crystallization; Crystallography, X-Ray; Enzyme Activation; Enzyme Inhibitors; Escherichia coli; Glutamic Acid; Kinetics; Mass Spectrometry; Metals; Models, Molecular; Mutagenesis, Site-Directed; Pyridones; Spectrophotometry, Ultraviolet | 1999 |
Inhibition of glutamine transport in rat brain mitochondria by some amino acids and tricarboxylic acid cycle intermediates.
Topics: Amino Acids; Animals; Asparagine; Aspartic Acid; Biological Transport; Brain; Citric Acid Cycle; Glutamic Acid; Glutamine; Ketoglutaric Acids; Kinetics; Malates; Mitochondria; Rats; Rats, Wistar; Succinic Acid | 1999 |
Relocation of the catalytic carboxylate group in class A beta-lactamase: the structure and function of the mutant enzyme Glu166-->Gln:Asn170-->Asp.
Topics: Acylation; Anti-Bacterial Agents; Asparagine; Aspartic Acid; beta-Lactamases; beta-Lactams; Catalytic Domain; Crystallography, X-Ray; Glutamic Acid; Glutamine; Kinetics; Models, Molecular; Mutation; Protein Conformation; Staphylococcus aureus; Structure-Activity Relationship | 1999 |
The effect of glutamate uptake inhibitors on hippocampal evoked potentials in vitro.
Topics: Animals; Asparagine; Dicarboxylic Acids; Evoked Potentials; Female; Glutamic Acid; Hippocampus; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neurotransmitter Uptake Inhibitors; Pyrrolidines | 1999 |
Mks1p is a regulator of nitrogen catabolism upstream of Ure2p in Saccharomyces cerevisiae.
Topics: Ammonia; Asparagine; Crosses, Genetic; Fungal Proteins; Gene Expression Regulation, Fungal; Genotype; Glutamic Acid; Glutamine; Glutathione Peroxidase; Nitrogen; Plasmids; Prions; Proline; Recombinant Proteins; Repressor Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Transcription Factors | 1999 |
Glutamate-containing parenteral nutrition doubles plasma glutamate: a risk factor in neurosurgical patients with blood-brain barrier damage?
Topics: Asparagine; Aspartic Acid; Blood-Brain Barrier; Brain Edema; Chromatography, High Pressure Liquid; Craniotomy; Female; Glutamic Acid; Glutamine; Hospitals, University; Humans; Intensive Care Units; Male; Middle Aged; Parenteral Nutrition; Prospective Studies; Risk Factors; Treatment Outcome | 1999 |
Streptolysin O: inhibition of the conformational change during membrane binding of the monomer prevents oligomerization and pore formation.
Topics: Alanine; Allosteric Regulation; Animals; Asparagine; Bacterial Proteins; Cysteine; Erythrocyte Membrane; Glutamic Acid; Lipid Bilayers; Membrane Proteins; Mutagenesis, Site-Directed; Point Mutation; Protein Binding; Protein Conformation; Rabbits; Sheep; Spectrometry, Fluorescence; Streptolysins; Temperature | 1999 |
Mutant trimers of light-harvesting complex II exhibit altered pigment content and spectroscopic features.
Topics: Asparagine; Binding Sites; Carotenoids; Chlorophyll; Glutamic Acid; Glutamine; Light-Harvesting Protein Complexes; Models, Molecular; Mutagenesis, Site-Directed; Photosynthetic Reaction Center Complex Proteins; Pisum sativum; Protein Folding; Recombinant Proteins; Spectrometry, Fluorescence; Spectrophotometry | 1999 |
Engineering a thermostable protein via optimization of charge-charge interactions on the protein surface.
Topics: Amino Acid Substitution; Arginine; Asparagine; Circular Dichroism; Glutamic Acid; Glutamine; Histidine; Linear Models; Lysine; Mutagenesis, Site-Directed; Protein Engineering; Protein Folding; Static Electricity; Surface Properties; Thermodynamics; Ubiquitins | 1999 |
Novel murine myeloid cell lines that exhibit a differentiation switch in response to IL-3 or GM-CSF, or to different constitutively active mutants of the GM-CSF receptor beta subunit.
Topics: Amino Acid Substitution; Animals; Asparagine; Cell Differentiation; Cell Line; Cell Line, Transformed; Glutamic Acid; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Stem Cells; Humans; Interleukin-3; Isoleucine; Macromolecular Substances; Mice; Receptors, Granulocyte-Macrophage Colony-Stimulating Factor; Receptors, Interleukin-3; Recombinant Proteins; Repetitive Sequences, Nucleic Acid; Valine | 2000 |
Asp-99 donates a hydrogen bond not to Tyr-14 but to the steroid directly in the catalytic mechanism of Delta 5-3-ketosteroid isomerase from Pseudomonas putida biotype B.
Topics: Asparagine; Aspartic Acid; Binding Sites; Catalysis; Equilenin; Glutamic Acid; Hydrogen Bonding; Kinetics; Macromolecular Substances; Mutagenesis, Site-Directed; Nandrolone; Pseudomonas putida; Steroid Isomerases; Tyrosine | 2000 |
Reactions of Pseudomonas 7A glutaminase-asparaginase with diazo analogues of glutamine and asparagine result in unexpected covalent inhibitions and suggests an unusual catalytic triad Thr-Tyr-Glu.
Topics: Amidohydrolases; Aminolevulinic Acid; Asparagine; Binding Sites; Catalysis; Catalytic Domain; Crystallography, X-Ray; Diazooxonorleucine; Electrons; Enzyme Inhibitors; Glutamic Acid; Glutamine; Pseudomonas; Threonine; Tyrosine | 2000 |
Presence of 2-furoylmethyl derivatives in hydrolysates of processed tomato products.
Topics: Alanine; Asparagine; Aspartic Acid; Chromatography, High Pressure Liquid; Freeze Drying; Furans; gamma-Aminobutyric Acid; Glutamic Acid; Hydrolysis; Lysine; Maillard Reaction; Serine; Solanum lycopersicum; Threonine | 2000 |
Site-directed mutagenesis identifies residues in uncoupling protein (UCP1) involved in three different functions.
Topics: Adipose Tissue, Brown; Amino Acid Substitution; Animals; Asparagine; Aspartic Acid; Binding Sites; Carrier Proteins; Chlorides; Cricetinae; Electron Transport; Glutamic Acid; Glutamine; Guanosine Triphosphate; Ion Channels; Membrane Proteins; Mitochondria; Mitochondrial Proteins; Mutagenesis, Site-Directed; Protons; Saccharomyces cerevisiae; Uncoupling Agents; Uncoupling Protein 1 | 2000 |
Investigation of spectroscopic intermediates during copper-binding and TPQ formation in wild-type and active-site mutants of a copper-containing amine oxidase from yeast.
Topics: Amine Oxidase (Copper-Containing); Asparagine; Aspartic Acid; Binding Sites; Coenzymes; Copper; Cysteine; Dihydroxyphenylalanine; Glutamic Acid; Glutamine; Histidine; Mutagenesis, Site-Directed; Oxygen Consumption; Pichia; Recombinant Proteins; Spectrophotometry, Atomic; Spectrophotometry, Ultraviolet | 2000 |
Mechanism of Ca2+-induced inhibition of Escherichia coli inorganic pyrophosphatase.
Topics: Alanine; Amino Acid Substitution; Asparagine; Aspartic Acid; Binding Sites; Calcium; Dialysis; Diphosphates; Escherichia coli; Glutamic Acid; Hydrolysis; Inorganic Pyrophosphatase; Kinetics; Lanthanum; Magnesium Compounds; Models, Molecular; Pyrophosphatases | 2000 |
Identification of mutations in rat CD59 that increase the complement regulatory activity.
Topics: Amino Acid Substitution; Animals; Antibodies, Monoclonal; Asparagine; Binding Sites, Antibody; CD59 Antigens; Cell Line; CHO Cells; Complement Inactivator Proteins; Complement Membrane Attack Complex; Complement Pathway, Classical; Cricetinae; Glutamic Acid; Humans; Lysine; Mutagenesis, Site-Directed; Polymerase Chain Reaction; Rabbits; Rats; Recombinant Proteins; Transfection | 2000 |
Deterministic features of side-chain main-chain hydrogen bonds in globular protein structures.
Topics: Amino Acids; Asparagine; Aspartic Acid; Crystallization; Glutamic Acid; Glutamine; Histidine; Hydrogen Bonding; Protein Conformation; Protein Structure, Secondary; Proteins; Serine; Threonine | 2000 |
Modeling the effects of mutations on the free energy of the first electron transfer from QA- to QB in photosynthetic reaction centers.
Topics: Alanine; Arginine; Asparagine; Aspartic Acid; Electron Transport; Energy Transfer; Glutamic Acid; Glutamine; Leucine; Models, Chemical; Mutagenesis, Site-Directed; Photosynthetic Reaction Center Complex Proteins; Quinones; Rhodobacter capsulatus; Rhodobacter sphaeroides; Static Electricity; Thermodynamics; Water | 2000 |
Selective methylation changes on the Bacillus subtilis chemotaxis receptor McpB promote adaptation.
Topics: Amino Acid Sequence; Amino Acid Substitution; Asparagine; Bacillus subtilis; Bacterial Proteins; Chemoreceptor Cells; Consensus Sequence; Genotype; Glutamic Acid; Glutamine; Membrane Proteins; Methanol; Methylation; Models, Biological; Mutagenesis, Site-Directed; Recombinant Proteins; Static Electricity | 2000 |
Hydrogen bonding and catalysis: a novel explanation for how a single amino acid substitution can change the pH optimum of a glycosidase.
Topics: Amino Acid Substitution; Asparagine; Aspartic Acid; Bacillus; Binding Sites; Catalysis; Crystallography, X-Ray; Disaccharides; Glutamic Acid; Glycoside Hydrolases; Glycosylation; Hydrogen Bonding; Hydrogen-Ion Concentration; Kinetics; Mass Spectrometry; Models, Chemical; Models, Molecular; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Protons; Static Electricity; Structure-Activity Relationship; Xylan Endo-1,3-beta-Xylosidase; Xylosidases | 2000 |
Effect of hypertrophic cardiomyopathy mutations in human cardiac muscle alpha -tropomyosin (Asp175Asn and Glu180Gly) on the regulatory properties of human cardiac troponin determined by in vitro motility assay.
Topics: Animals; Asparagine; Aspartic Acid; Calcium; Cardiomegaly; Cardiomyopathies; Cell Movement; Dose-Response Relationship, Drug; Glutamic Acid; Glycine; Heart; Humans; Microscopy, Fluorescence; Muscle Fibers, Fast-Twitch; Muscle, Skeletal; Mutagenesis; Myocardium; Rabbits; Recombinant Proteins; Tropomyosin; Troponin | 2000 |
[The levels of the neuro-mediating amino acids in the blood of patients with alcoholic delirium].
Topics: Adult; Aged; Alcohol Withdrawal Delirium; Alcohol-Related Disorders; Asparagine; Delirium; Glutamic Acid; Glycine; Humans; Male; Middle Aged | 2000 |
Glutamine metabolism in endothelial cells: ornithine synthesis from glutamine via pyrroline-5-carboxylate synthase.
Topics: Alanine; Ammonia; Animals; Antimetabolites, Antineoplastic; Aorta; Asparagine; Aspartic Acid; Azaserine; Carbon Dioxide; Cattle; Cells, Cultured; Diazooxonorleucine; Endothelium, Vascular; Enzymes; Glutamic Acid; Glutamine; Humans; Microcirculation; Ornithine; Ornithine-Oxo-Acid Transaminase; Umbilical Veins; Venules | 2000 |
Two clusters of acidic amino acids near the NH2 terminus of complement component C4 alpha'-chain are important for C2 binding.
Topics: Amino Acid Sequence; Amino Acids; Animals; Antibodies, Blocking; Asparagine; Aspartic Acid; Binding Sites, Antibody; Complement C2; Complement C4; COS Cells; Glutamic Acid; Glutamine; Humans; Molecular Mimicry; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Protein Binding | 2000 |
The structure of a CREB bZIP.somatostatin CRE complex reveals the basis for selective dimerization and divalent cation-enhanced DNA binding.
Topics: Amino Acid Sequence; Arginine; Asparagine; Cations; Crystallography, X-Ray; Cyclic AMP Response Element-Binding Protein; Dimerization; DNA; DNA-Binding Proteins; Dose-Response Relationship, Drug; Electrons; Escherichia coli; Glutamic Acid; Glutamine; Hydrogen Bonding; Ions; Kinetics; Leucine Zippers; Lysine; Magnesium; Models, Molecular; Molecular Sequence Data; Protein Structure, Secondary; Response Elements; Sequence Homology, Amino Acid; Signal Transduction; Somatostatin | 2000 |
Mutagenesis and kinetic studies of a plant cysteine proteinase with an unusual arrangement of acidic amino acids in and around the active site.
Topics: Alanine; Amino Acid Sequence; Asparagine; Aspartic Acid; Binding Sites; Cloning, Molecular; Cysteine Endopeptidases; DNA, Complementary; Escherichia coli; Glutamic Acid; Hydrogen-Ion Concentration; Kinetics; Magnoliopsida; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Plant Proteins; Protein Precursors; Protein Structure, Tertiary; Recombinant Proteins; Sequence Homology, Amino Acid; Structure-Activity Relationship | 2000 |
Contribution of salt bridges near the surface of a protein to the conformational stability.
Topics: Amino Acid Substitution; Asparagine; Aspartic Acid; Calorimetry, Differential Scanning; Crystallization; Crystallography, X-Ray; Glutamic Acid; Glutamine; Hot Temperature; Humans; Hydrogen-Ion Concentration; Muramidase; Mutagenesis, Site-Directed; Potassium Chloride; Protein Conformation; Protein Denaturation; Salts; Surface Properties | 2000 |
Redesigning the substrate specificity of an enzyme: isocitrate dehydrogenase.
Topics: 3-Isopropylmalate Dehydrogenase; Alcohol Oxidoreductases; Amino Acid Sequence; Amino Acid Substitution; Asparagine; Enzyme Activation; Escherichia coli; Glutamic Acid; Helix-Loop-Helix Motifs; Isocitrate Dehydrogenase; Isocitrates; Malates; Molecular Sequence Data; Mutagenesis, Insertional; Mutagenesis, Site-Directed; Protein Engineering; Protein Structure, Secondary; Recombinant Fusion Proteins; Serine; Substrate Specificity; Thermus thermophilus; Thiobacillus; Valine | 2000 |
DNA polymerase beta: contributions of template-positioning and dNTP triphosphate-binding residues to catalysis and fidelity.
Topics: Animals; Arginine; Asparagine; Binding Sites; Catalysis; Crystallization; Crystallography, X-Ray; Deoxyribonucleotides; DNA Polymerase beta; DNA-Binding Proteins; Glutamic Acid; Kinetics; Lysine; Mutagenesis, Site-Directed; Nuclear Magnetic Resonance, Biomolecular; Rats; Recombinant Proteins; Serine; Structure-Activity Relationship; Templates, Genetic | 2000 |
Poly(amino acid) bioadhesives for tissue repair.
Topics: Adhesiveness; Amino Acids; Animals; Asparagine; Aspartic Acid; Biocompatible Materials; Cartilage; Cattle; Chondroitin Sulfates; Glass; Glutamic Acid; Hydrogen Bonding; Lysine; Materials Testing; Models, Chemical; Models, Molecular; Permeability; Tissue Adhesions; Tissue Adhesives; Wound Healing; Wounds and Injuries | 2000 |
Topology and structure of the C1q-binding site on C-reactive protein.
Topics: Amino Acid Substitution; Asparagine; Binding Sites; C-Reactive Protein; Complement Activation; Complement C1q; Glutamic Acid; Histidine; Humans; Models, Molecular; Mutagenesis, Site-Directed; Phosphorylcholine; Polysaccharides, Bacterial; Serum Albumin, Bovine; Streptococcus pneumoniae; Threonine; Tyrosine | 2001 |
The role for an invariant aspartic acid in hypoxanthine phosphoribosyltransferases is examined using saturation mutagenesis, functional analysis, and X-ray crystallography.
Topics: Alanine; Amino Acid Substitution; Animals; Asparagine; Aspartic Acid; Crystallography, X-Ray; Enzyme Activation; Escherichia coli; Genetic Complementation Test; Glutamic Acid; Glutamine; Humans; Hydrogen-Ion Concentration; Hypoxanthine Phosphoribosyltransferase; Kinetics; Mutagenesis, Site-Directed; Plasmodium falciparum; Recombinant Proteins; Structure-Activity Relationship; Substrate Specificity | 2001 |
Probing functional perfection in substructures of ribonuclease T1: double combinatorial random mutagenesis involving Asn43, Asn44, and Glu46 in the guanine binding loop.
Topics: Amino Acid Substitution; Asparagine; Bacterial Proteins; Combinatorial Chemistry Techniques; Conserved Sequence; Enzyme Activation; Fungal Proteins; Glutamic Acid; Guanine; Kinetics; Mutagenesis, Site-Directed; Recombinant Proteins; Ribonuclease T1; Sequence Deletion; Substrate Specificity; Transformation, Genetic | 2001 |
Structures of the acyl-enzyme complexes of the Staphylococcus aureus beta-lactamase mutant Glu166Asp:Asn170Gln with benzylpenicillin and cephaloridine.
Topics: Acylation; Amino Acid Substitution; Asparagine; Aspartic Acid; beta-Lactamases; Binding Sites; Catalysis; Cephaloridine; Crystallization; Crystallography, X-Ray; Escherichia coli; Glutamic Acid; Glutamine; Hydrolysis; Kinetics; Macromolecular Substances; Mutagenesis, Site-Directed; Penicillin G; Staphylococcus aureus; Substrate Specificity | 2001 |
ENDOR structural characterization of a catalytically competent acylenzyme reaction intermediate of wild-type TEM-1 beta-lactamase confirms glutamate-166 as the base catalyst.
Topics: Acylation; Asparagine; beta-Lactamase Inhibitors; beta-Lactamases; Binding Sites; Catalysis; Deuterium; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Escherichia coli; Freezing; Glutamic Acid; Hydrolysis; Kinetics; Mutagenesis, Site-Directed; Penicillanic Acid; Penicillin G; Solvents; Spin Labels; Water | 2001 |
The crystal structure of phosphinothricin in the active site of glutamine synthetase illuminates the mechanism of enzymatic inhibition.
Topics: Aminobutyrates; Asparagine; Aspartic Acid; Binding Sites; Catalysis; Computer Simulation; Crystallography, X-Ray; Electrons; Enzyme Inhibitors; Glutamate-Ammonia Ligase; Glutamic Acid; Models, Molecular; Salmonella typhimurium; Spectroscopy, Fourier Transform Infrared; Static Electricity; Substrate Specificity; Thallium; Tyrosine | 2001 |
Thermodynamics of metal ion binding. 2. Metal ion binding by carbonic anhydrase variants.
Topics: Asparagine; Binding Sites; Calorimetry; Carbonic Anhydrases; Cations, Divalent; Glutamic Acid; Glutamine; Histidine; Humans; Hydrogen Bonding; Ligands; Mutagenesis, Site-Directed; Protein Binding; Thermodynamics; Zinc | 2001 |
Stabilization of apoflavodoxin by replacing hydrogen-bonded charged Asp or Glu residues by the neutral isosteric Asn or Gln.
Topics: Amino Acid Substitution; Anabaena; Apoproteins; Asparagine; Aspartic Acid; Bacterial Proteins; Base Sequence; Circular Dichroism; Cyanobacteria; Flavodoxin; Glutamic Acid; Glutamine; Hot Temperature; Hydrogen Bonding; Hydrogen-Ion Concentration; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation; Protein Denaturation; Urea | 2001 |
Active site residues of glutamate racemase.
Topics: Amino Acid Isomerases; Amino Acid Sequence; Asparagine; Aspartic Acid; Bacterial Proteins; Binding Sites; Deuterium; Glutamic Acid; Glutamine; Histidine; Isoenzymes; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Recombinant Proteins; Sequence Alignment | 2001 |
Folate activation and catalysis in methylenetetrahydrofolate reductase from Escherichia coli: roles for aspartate 120 and glutamate 28.
Topics: Amino Acid Substitution; Asparagine; Aspartic Acid; Catalysis; Enzyme Activation; Escherichia coli; Folic Acid; Glutamic Acid; Glutamine; Kinetics; Methylenetetrahydrofolate Dehydrogenase (NAD+); Methylenetetrahydrofolate Reductase (NADPH2); Mutagenesis, Site-Directed; NAD; NAD(P)H Dehydrogenase (Quinone); Oxidation-Reduction; Oxidoreductases; Oxidoreductases Acting on CH-NH Group Donors; Spectrophotometry; Vitamin K | 2001 |
Catalytic acid-base groups in yeast pyruvate decarboxylase. 3. A steady-state kinetic model consistent with the behavior of both wild-type and variant enzymes at all relevant pH values.
Topics: Acetaldehyde; Alanine; Amino Acid Substitution; Asparagine; Aspartic Acid; Binding Sites; Catalytic Domain; Computer Simulation; Glutamic Acid; Glutamine; Hydrogen-Ion Concentration; Kinetics; Models, Chemical; Pyruvate Decarboxylase; Pyruvates; Recombinant Proteins; Saccharomyces cerevisiae; Substrate Specificity | 2001 |
A Ty1 reverse transcriptase active-site aspartate mutation blocks transposition but not polymerization.
Topics: Amino Acid Substitution; Asparagine; Aspartic Acid; Binding Sites; Glutamic Acid; Mutation; Retroelements; RNA-Directed DNA Polymerase; Transcription, Genetic; Yeasts | 2001 |
A program of Yersinia enterocolitica type III secretion reactions is activated by specific signals.
Topics: Albumins; Asparagine; Aspartic Acid; Bacterial Outer Membrane Proteins; Calcium; Genes, Regulator; Glutamic Acid; Glutamine; HeLa Cells; Humans; Mutation; Signal Transduction; Yersinia enterocolitica | 2001 |
Capture of a dimeric intermediate during transthyretin amyloid formation.
Topics: Amyloid; Amyloid Neuropathies, Familial; Anilino Naphthalenesulfonates; Asparagine; Dimerization; Fluorescent Dyes; Glutamic Acid; Guanidine; Humans; Models, Molecular; Mutation; Prealbumin; Protein Binding; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Recombinant Proteins; Staining and Labeling; Temperature; Thyroxine; Valine | 2001 |
Amino acid metabolism of bovine blastocysts derived from parthenogenetically activated or in vitro fertilized oocytes.
Topics: Alanine; Amino Acids; Animals; Asparagine; Blastocyst; Cattle; Cryopreservation; Culture Techniques; Female; Fertilization in Vitro; Glutamic Acid; Glutamine; Glycine; Oocytes; Parthenogenesis; Serine | 1998 |
Simultaneous replacement of Asp-L210 and Asp-M17 with Asn increases proton uptake by Glu-L212 upon first electron transfer to QB in reaction centers from Rhodobacter sphaeroides.
Topics: Amino Acid Substitution; Asparagine; Aspartic Acid; Deuterium Oxide; Electron Transport; Glutamic Acid; Glutamine; Mutagenesis, Site-Directed; Photosynthetic Reaction Center Complex Proteins; Protons; Quinones; Rhodobacter sphaeroides; Spectroscopy, Fourier Transform Infrared | 2001 |
Beta-amyloid fibrils activate the C1 complex of complement under physiological conditions: evidence for a binding site for A beta on the C1q globular regions.
Topics: Amino Acid Sequence; Amyloid beta-Peptides; Animals; Asparagine; Aspartic Acid; Binding Sites; Complement C1; Complement C1q; Complement Pathway, Classical; Glutamic Acid; Glutamine; Humans; Hydrogen-Ion Concentration; Molecular Sequence Data; Peptide Fragments; Protein Structure, Tertiary; Rats | 2001 |
Study of asparagine 353 in aminopeptidase A: characterization of a novel motif (GXMEN) implicated in exopeptidase specificity of monozinc aminopeptidases.
Topics: Amino Acid Sequence; Aminopeptidases; Angiotensin II; Animals; Asparagine; CHO Cells; Consensus Sequence; Cricetinae; DNA Primers; Escherichia coli; Fluorescent Antibody Technique; Glutamic Acid; Glutamyl Aminopeptidase; Humans; Hydrolysis; Kinetics; Metalloendopeptidases; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Polymerase Chain Reaction; Precipitin Tests; Recombinant Proteins; Sequence Homology, Amino Acid; Zinc | 2001 |
Conformational and dynamic characterization of the molten globule state of an apomyoglobin mutant with an altered folding pathway.
Topics: Apoproteins; Asparagine; Circular Dichroism; Fluorescence; Glutamic Acid; Glycine; Hydrogen; Hydrogen Bonding; Kinetics; Magnetic Resonance Spectroscopy; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Myoglobin; Peptide Fragments; Protein Conformation; Protein Folding; Protein Structure, Secondary | 2001 |
Residues 137 and 153 at the N terminus of the XylS protein influence the effector profile of this transcriptional regulator and the sigma factor used by RNA polymerase to stimulate transcription from its cognate promoter.
Topics: Amino Acids; Asparagine; Aspartic Acid; Bacterial Proteins; beta-Galactosidase; DNA; DNA-Binding Proteins; DNA-Directed RNA Polymerases; Escherichia coli; Glutamic Acid; Histidine; Mutation; Plasmids; Point Mutation; Promoter Regions, Genetic; Protein Structure, Tertiary; RNA; Trans-Activators; Transcription, Genetic | 2002 |
Importance of Na,K-ATPase residue alpha 1-Arg544 in the segment Arg544-Asp567 for high-affinity binding of ATP, ADP, or MgATP.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Alanine; Amino Acid Substitution; Animals; Arginine; Asparagine; Aspartic Acid; Binding Sites; Conserved Sequence; Cysteine; Glutamic Acid; Magnesium; Mutagenesis, Site-Directed; Peptide Fragments; Phosphorylation; Saccharomyces cerevisiae; Serine; Sodium-Potassium-Exchanging ATPase; Swine; Thermodynamics | 2002 |
ADAMTS4 cleaves at the aggrecanase site (Glu373-Ala374) and secondarily at the matrix metalloproteinase site (Asn341-Phe342) in the aggrecan interglobular domain.
Topics: ADAM Proteins; ADAMTS4 Protein; Alanine; Amino Acid Sequence; Asparagine; Binding Sites; Cathepsin B; Glutamic Acid; Humans; Hydrogen-Ion Concentration; Matrix Metalloproteinases; Metalloendopeptidases; Oligopeptides; Phenylalanine; Procollagen N-Endopeptidase; Substrate Specificity; Tissue Inhibitor of Metalloproteinase-1 | 2002 |
Enthalpic homogeneous pair interaction coefficients of L-alpha-amino acids as a hydrophobicity parameter of amino acid side chains.
Topics: Amino Acids; Arginine; Asparagine; Calorimetry; Cysteine; Glutamic Acid; Glutamine; Histidine; Solutions; Stereoisomerism; Thermodynamics; Tryptophan; Water | 2002 |
An essential amino acid residue for catalytic activity of the dextranase of Streptococcus mutans.
Topics: Amino Acid Sequence; Amino Acids, Essential; Asparagine; Aspartic Acid; Binding Sites; Dextranase; Glucosyltransferases; Glutamic Acid; Humans; Molecular Biology; Mutagenesis, Site-Directed; Sequence Analysis, Protein; Streptococcus; Streptococcus mutans; Streptococcus sobrinus; Threonine; Valine | 2002 |
Effect of replacing the aspartic acid/glutamic acid residues of bullfrog sialic acid binding lectin with asparagine/glutamine and arginine on the inhibition of cell proliferation in murine leukemia P388 cells.
Topics: Amino Acid Substitution; Animals; Antineoplastic Agents; Arginine; Asparagine; Aspartic Acid; Cell Division; Circular Dichroism; Cloning, Molecular; Escherichia coli; Glutamic Acid; HL-60 Cells; Humans; Lectins; Leukemia P388; Mice; Microscopy, Fluorescence; Mutagenesis, Site-Directed; N-Acetylneuraminic Acid; Rana catesbeiana; Ribonucleases | 2002 |
Compound heterozygosity for Hb Korle-Bu (beta(73); Asp-Asn) and Hb E (beta(26); Glu-Lys) with a 3.7-kb deletional alpha-thalassemia in Thai patients.
Topics: Adolescent; Adult; Aged; alpha-Thalassemia; Asparagine; Aspartic Acid; Base Sequence; Chromosome Segregation; Female; Gene Deletion; Glutamic Acid; Hemoglobin E; Hemoglobins, Abnormal; Heterozygote; Humans; Lysine; Male; Middle Aged; Pregnancy; Thailand | 2002 |
Excitatory amino acid release in the spinal cord caused by plantar incision in the rat.
Topics: Animals; Asparagine; Aspartic Acid; Dermatologic Surgical Procedures; Glutamic Acid; Glutamine; Glycine; Male; Microdialysis; Pain, Postoperative; Rats; Rats, Sprague-Dawley; Serine; Spinal Cord | 2002 |
Halide-stabilizing residues of haloalkane dehalogenases studied by quantum mechanic calculations and site-directed mutagenesis.
Topics: Amino Acids; Anions; Asparagine; Glutamic Acid; Halogens; Histidine; Hydrolases; Isoleucine; Leucine; Mathematical Computing; Models, Chemical; Mutagenesis, Site-Directed; Phenylalanine; Proline; Quantum Theory; Static Electricity; Tryptophan; Valine | 2002 |
Atomic dissection of the hydrogen bond network for transition-state analogue binding to purine nucleoside phosphorylase.
Topics: Animals; Asparagine; Binding Sites; Catalysis; Cattle; Crystallography, X-Ray; Enzyme Inhibitors; Glutamic Acid; Hydrogen Bonding; Hydrogen-Ion Concentration; Hypoxanthine; Imines; Nuclear Magnetic Resonance, Biomolecular; Purine Nucleosides; Purine-Nucleoside Phosphorylase; Pyrimidinones; Pyrroles; Ribonucleosides; Static Electricity; Substrate Specificity; Thermodynamics | 2002 |
Chemical rescue of proton transfer in catalysis by carbonic anhydrases in the beta- and gamma-class.
Topics: Alanine; Arabidopsis Proteins; Archaeal Proteins; Asparagine; Carbonic Anhydrase II; Carbonic Anhydrases; Catalysis; Electron Transport; Glutamic Acid; Histidine; Humans; Isoenzymes; Methanosarcina; Mutagenesis, Site-Directed; Protons | 2002 |
Amino acid substitutions at position 43 of NaeI endonuclease. Evidence for changes in NaeI structure.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Amino Acids; Asparagine; Chromatography; Circular Dichroism; Crystallography, X-Ray; Deoxyribonucleases, Type II Site-Specific; Dimerization; DNA Ligases; DNA Restriction Enzymes; DNA Topoisomerases; Dose-Response Relationship, Drug; Escherichia coli; Glutamic Acid; Histidine; Leucine; Models, Molecular; Molecular Sequence Data; Mutation; Protein Binding; Protein Conformation; Proteins; Sequence Homology, Amino Acid; Temperature; Ultraviolet Rays | 2003 |
Structural and biochemical exploration of a critical amino acid in human 8-oxoguanine glycosylase.
Topics: Amino Acid Sequence; Asparagine; Aspartic Acid; Binding Sites; Catalysis; Circular Dichroism; Crystallography, X-Ray; DNA; DNA-Formamidopyrimidine Glycosylase; Electrophoresis, Polyacrylamide Gel; Enzyme Stability; Glutamic Acid; Glutamine; Hot Temperature; Humans; Hydrolysis; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; N-Glycosyl Hydrolases; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Substrate Specificity | 2003 |
Engineering a catalytic metal binding site into a calcium-independent phosphatidylinositol-specific phospholipase C leads to enhanced stereoselectivity.
Topics: Animals; Arginine; Asparagine; Aspartic Acid; Bacillus; Bacterial Proteins; Binding Sites; Calcium; Catalytic Domain; Cattle; Glutamic Acid; Glutamine; Metals, Alkaline Earth; Mutagenesis, Site-Directed; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoinositide Phospholipase C; Stereoisomerism; Streptomyces antibioticus; Substrate Specificity; Type C Phospholipases | 2003 |
Redox potential of quinones in photosynthetic reaction centers from Rhodobacter sphaeroides: dependence on protonation of Glu-L212 and Asp-L213.
Topics: Amino Acid Substitution; Asparagine; Aspartic Acid; Deuterium Oxide; Electron Transport; Glutamic Acid; Glutamine; Light; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Oxidation-Reduction; Photosynthetic Reaction Center Complex Proteins; Protein Conformation; Protons; Quinones; Rhodobacter sphaeroides; Spectroscopy, Fourier Transform Infrared | 2003 |
Increased lysine synthesis coupled with a knockout of its catabolism synergistically boosts lysine content and also transregulates the metabolism of other amino acids in Arabidopsis seeds.
Topics: Amino Acids; Arabidopsis; Asparagine; Aspartic Acid; Bacteria; Bacterial Proteins; Gene Expression Regulation, Plant; Germination; Glutamic Acid; Glutamine; Hydro-Lyases; Lysine; Methionine; Mutation; Plants, Genetically Modified; Pterocarpans; Seeds; Signal Transduction; Threonine | 2003 |
Extracellular vestibule determinants of Ca2+ influx in Ca2+-permeable AMPA receptor channels.
Topics: Amino Acid Sequence; Amino Acid Substitution; Arginine; Asparagine; Calcium; Cell Line; Conserved Sequence; Electric Conductivity; Extracellular Space; GluK2 Kainate Receptor; Glutamic Acid; Humans; Ion Channels; Molecular Sequence Data; Permeability; Receptors, AMPA; Receptors, Kainic Acid | 2003 |
Plasma amino acid levels in children with autism and their families.
Topics: Adolescent; Alanine; Amino Acids; Asparagine; Asperger Syndrome; Autistic Disorder; Brain Diseases, Metabolic, Inborn; Child; Child, Preschool; Family; Female; Glutamic Acid; Glutamine; Humans; Lysine; Male; Phenylalanine; Tyrosine | 2003 |
Identification of the L-aspartate transporter in Bacillus subtilis.
Topics: Amino Acid Transport Systems, Acidic; Amino Acids; Asparagine; Aspartic Acid; Bacillus subtilis; Bacterial Proteins; Carrier Proteins; Cell Division; Cloning, Molecular; Glutamic Acid; Mutation; Phylogeny; Recombinant Fusion Proteins; Substrate Specificity | 2003 |
Breast and lung cancer are associated with a decrease in blood cell amino acid content.
Topics: Adult; Aged; Amino Acids; Amino Acids, Essential; Asparagine; Blood Cells; Breast Neoplasms; Female; Glutamic Acid; Humans; Lung Neoplasms; Male; Middle Aged; Ornithine; Plasma; Proline; Valine | 2003 |
Point mutations at L1280 in Nav1.4 channel D3-S6 modulate binding affinity and stereoselectivity of bupivacaine enantiomers.
Topics: Amino Acid Substitution; Anesthetics, Local; Animals; Asparagine; Bupivacaine; Cells, Cultured; Glutamic Acid; Glutamine; Humans; Mutagenesis, Site-Directed; Point Mutation; Rats; Sodium Channel Blockers; Sodium Channels; Stereoisomerism | 2003 |
Extracellular glutamate and other amino acids in experimental intracerebral hemorrhage: an in vivo microdialysis study.
Topics: Analysis of Variance; Animals; Asparagine; Aspartic Acid; Brain Ischemia; Cerebral Hemorrhage; Chromatography, High Pressure Liquid; Disease Models, Animal; Extracellular Space; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Male; Microdialysis; Prospective Studies; Rabbits; Single-Blind Method; Stroke; Taurine; Time Factors | 2003 |
Crystal structure of the Yersinia protein-tyrosine phosphatase YopH complexed with a specific small molecule inhibitor.
Topics: Amino Acid Sequence; Arginine; Asparagine; Bacterial Outer Membrane Proteins; Catalytic Domain; Catechols; Crystallography, X-Ray; DNA Mutational Analysis; Dose-Response Relationship, Drug; Glutamic Acid; Hydrolysis; Kinetics; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Protein Tyrosine Phosphatases; Sequence Homology, Amino Acid; Yersinia pestis | 2003 |
Deletions of any single residues in Glu40-Ser48 loop connecting a domain and the first transmembrane helix of sarcoplasmic reticulum Ca(2+)-ATPase result in almost complete inhibition of conformational transition and hydrolysis of phosphoenzyme intermedia
Topics: Adenosine Triphosphate; Animals; Asparagine; Calcium-Transporting ATPases; COS Cells; Enzyme Activation; Gene Deletion; Glutamic Acid; Hydrogen Bonding; Hydrolysis; Lysine; Microsomes; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Protein Conformation; Protein Structure, Tertiary; Rabbits; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Serine | 2003 |
Sequence context strongly modulates association of polar residues in transmembrane helices.
Topics: Amino Acid Sequence; Amino Acids, Acidic; Amino Acids, Basic; Asparagine; Aspartic Acid; Capsid; Capsid Proteins; Glutamic Acid; Glutamine; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Membrane Proteins; Protein Structure, Tertiary; Recombinant Fusion Proteins | 2003 |
Lipoprotein lipase activity and common gene variants in severely hypertriglyceridemic patients with and without diabetes.
Topics: Adult; Apolipoproteins; Asparagine; Aspartic Acid; Diabetes Complications; Diabetes Mellitus; Female; Genetic Variation; Glutamic Acid; Glycine; Humans; Hyperlipoproteinemia Type IV; Lipoprotein Lipase; Male; Middle Aged; Phenotype; Serine; Severity of Illness Index | 2003 |
Specific isotopic labeling and photooxidation-linked structural changes in the manganese-stabilizing subunit of photosystem II.
Topics: Asparagine; Aspartic Acid; Escherichia coli; Gas Chromatography-Mass Spectrometry; Gene Expression; Glutamic Acid; Glutamine; Isotope Labeling; Manganese; Oxidation-Reduction; Photochemistry; Photosynthesis; Photosystem II Protein Complex; Recombinant Proteins; Spectroscopy, Fourier Transform Infrared; Water | 2003 |
Evolution of amino acid metabolism inferred through cladistic analysis.
Topics: Amino Acids; Asparagine; Aspartic Acid; Biochemical Phenomena; Biochemistry; Biological Evolution; Citric Acid Cycle; Enzymes; Glutamic Acid; Glutamine; Models, Biological; Multigene Family; Phylogeny; Software; Statistics as Topic; Substrate Specificity | 2003 |
The inhibition by neopyrithiamine of asparagine synthesis from glutamic acid and glucose.
Topics: Asparagine; Biochemical Phenomena; Glucose; Glutamic Acid; Pyrimidines; Pyrithiamine | 1954 |
Diminished phenylketonuria in phenylpyruvic oligophrenia after administration of L-glutamine, L-glutamate or L-asparagine.
Topics: Asparagine; Body Fluids; Glutamic Acid; Glutamine; Humans; Intellectual Disability; Ketones; Phenylketonurias; Urine | 1956 |
Comparative potencies of tuberculins produced on asparagine and ammonium glutamate mediums.
Topics: Ammonium Compounds; Animals; Asparagine; Glutamates; Glutamic Acid; Tuberculin | 1958 |
Effect of withholding glutamic acid and asparagine on the germination of spores of Bacillus subtilis.
Topics: Asparagine; Bacillus subtilis; Glutamates; Glutamic Acid; Spores, Bacterial | 1959 |
Metabolic characterization of the genus Brucella. I. Statistical evaluation of the oxidative rates by which type I of each species can be identified.
Topics: Alanine; Amino Acids; Arabinose; Arginine; Asparagine; Brucella; Brucella abortus; Brucella melitensis; Brucella suis; Brucellosis; Carbohydrate Metabolism; Galactose; Glutamic Acid; Lysine; Ornithine; Oxidation-Reduction; Ribose; Xylose | 1961 |
[Effect of glutamic acid, asparagine, glycocoll and alanine on the contractile function of the skeletal muscle and on its sensitization to potassium ions].
Topics: Alanine; Asparagine; Glutamates; Glutamic Acid; Glycine; Ions; Muscle Contraction; Muscle, Skeletal; Muscles; Potassium | 1962 |
Heat capacities from 11 to 305 degree K, entropies and free energies of formation of L-asparagine monohydrate, L-aspartic acid, L-glutamic acid, and L-glutamine.
Topics: Asparagine; Aspartic Acid; Entropy; Glutamates; Glutamic Acid; Glutamine; Hot Temperature | 1963 |
THE BIOSYNTHESIS OF ASPARAGINE IN THE ETIOLATED SOYBEAN SEEDLING. II. CONVERSION IN VITRO OF GLUTAMIC ACID AND ASPARTIC ACID TO ASPARAGINE.
Topics: Asparagine; Aspartate Aminotransferases; Aspartic Acid; Darkness; Glutamates; Glutamic Acid; Glycine max; In Vitro Techniques; Plant Proteins; Proteins; Research; Seedlings | 1963 |
ENZYMATIC SYNTHESIS OF GAMMA-GLUTAMYLHYDROXAMIC ACID FROM GLUTAMIC ACID AND HYDROXYLAMINE.
Topics: Amidohydrolases; Ammonia; Antimetabolites; Asparagine; Azaserine; Azotobacter; Carbon Isotopes; Glutamates; Glutamic Acid; Glutaminase; Glutamine; Hydroxamic Acids; Hydroxylamine; Hydroxylamines; Pharmacology; Proteins; Research; Streptomycin | 1963 |
[CONCERNING LINKED PRODUCTS OF GLUTAMIC ACID, GLUTAMINE, ASPARAGINE AND AROMATIC CARBOXYLIC ACIDS].
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Animals; Asparagine; Benzoates; Chromatography; Glutamates; Glutamic Acid; Glutamine; Guinea Pigs; Hippurates; Kidney; Liver; Metabolism; Phenylacetates; Rats; Research; Ultraviolet Rays | 1964 |
AMINO GROUP FORMATION AND GLUTAMATE SYNTHESIS IN STREPTOCOCCUS BOVIS.
Topics: Amino Acids; Asparagine; Aspartic Acid; Carbon; Caseins; Culture Media; Glutamate Dehydrogenase; Glutamates; Glutamic Acid; Glyceraldehyde-3-Phosphate Dehydrogenases; Isocitrate Dehydrogenase; Metabolism; NAD; NADP; Nitrogen; Nucleotides; Research; Streptococcus; Streptococcus bovis | 1964 |
AMINO ACID UTILIZATION BY ALCALIGENES VISCOLACTIS FOR GROWTH AND SLIME PRODUCTION.
Topics: Alcaligenes; Amino Acids; Asparagine; Aspartic Acid; Carbohydrate Metabolism; Colorimetry; Culture Media; Glucose; Glutamic Acid; Glutamine; Lactose; Nitrogen; Proline; Research; Salts; Tyrosine | 1965 |
[The modulating role of essential and non-essential amino acids in organotypic tissue culture in rats of different ages].
Topics: Aging; Amino Acids; Amino Acids, Essential; Animals; Arginine; Asparagine; Cerebral Cortex; Culture Media; Glutamic Acid; Liver; Lysine; Organ Culture Techniques; Rats; Rats, Wistar; Spleen | 2003 |
Identification of Pseudomonas proteins coordinately induced by acidic amino acids and their amides: a two-dimensional electrophoresis study.
Topics: Asparaginase; Asparagine; Aspartic Acid; Bacterial Proteins; Glutamic Acid; Glutaminase; Glutamine; Periplasm; Proteomics; Pseudomonas fluorescens; Pseudomonas putida; Reverse Transcriptase Polymerase Chain Reaction; Sigma Factor | 2003 |
Site within N-Methyl-D-aspartate receptor pore modulates channel gating.
Topics: Asparagine; Calcium; Cells, Cultured; Glutamic Acid; Humans; Ion Channels; Mutagenesis, Site-Directed; Mutation; Protein Structure, Secondary; Receptors, N-Methyl-D-Aspartate; Transfection; Tyrosine | 2004 |
The Q267E mutation in the sodium/iodide symporter (NIS) causes congenital iodide transport defect (ITD) by decreasing the NIS turnover number.
Topics: Alanine; Amino Acid Substitution; Animals; Asparagine; Biological Transport; Biotinylation; Cell Line; Cell Membrane; COS Cells; Glutamic Acid; Glutamine; Humans; Iodides; Kinetics; Mutation, Missense; Sodium; Symporters; Thyroid Gland | 2004 |
Mutational analysis of different regions in the coxsackievirus 2B protein: requirements for homo-multimerization, membrane permeabilization, subcellular localization, and virus replication.
Topics: Amino Acid Sequence; Animals; Arginine; Asparagine; Aspartic Acid; Cell Line; Cell Membrane; Chlorocebus aethiops; COS Cells; Dimerization; DNA Mutational Analysis; Enterovirus; Glutamic Acid; Hygromycin B; Kinetics; Lysine; Microscopy, Confocal; Microscopy, Fluorescence; Molecular Sequence Data; Mutation; Oligonucleotides, Antisense; Permeability; Protein Structure, Tertiary; RNA; Subcellular Fractions; Time Factors; Transfection; Tryptophan; Two-Hybrid System Techniques; Viral Nonstructural Proteins; Virus Replication | 2004 |
Function of conserved residues of human glutathione synthetase: implications for the ATP-grasp enzymes.
Topics: Adenosine Triphosphate; Asparagine; Binding Sites; Catalysis; Circular Dichroism; Conserved Sequence; Crystallography, X-Ray; DNA; Glutamic Acid; Glutathione; Glutathione Synthase; Humans; Kinetics; Ligands; Lysine; Models, Chemical; Models, Molecular; Multigene Family; Mutagenesis, Site-Directed; Mutation; Protein Structure, Tertiary; Recombinant Proteins; Software | 2004 |
alpha-Tropomyosin mutations Asp(175)Asn and Glu(180)Gly affect cardiac function in transgenic rats in different ways.
Topics: Animals; Animals, Genetically Modified; Asparagine; Aspartic Acid; Biomarkers; Calcium; Cardiomyopathy, Hypertrophic, Familial; Gene Expression; Glutamic Acid; Glycine; Heart; Heart Ventricles; Humans; Immunohistochemistry; In Vitro Techniques; Muscle Fibers, Skeletal; Mutation, Missense; Myocardial Contraction; Myocytes, Cardiac; Rats; Sarcomeres; Transgenes; Tropomyosin | 2004 |
Domain structures and roles in bacteriophage HK97 capsid assembly and maturation.
Topics: Asparagine; Aspartic Acid; Capsid; Coliphages; Crystallization; Cysteine; Glutamic Acid; Lysine; Protein Precursors; Protein Structure, Secondary; Protein Structure, Tertiary; Protein Subunits; Spectrum Analysis, Raman; Tryptophan; Tyrosine; Virus Assembly | 2004 |
Quantum molecular dynamics simulation of proton transfer in cytochrome c oxidase.
Topics: Asparagine; Computer Simulation; Electron Transport Complex IV; Glutamic Acid; Hydrogen Bonding; Magnesium; Models, Molecular; Oxygen; Protein Conformation; Protons; Quantum Theory; Rhodobacter sphaeroides; Thermodynamics; Water | 2004 |
Metabolomic differentiation of Cannabis sativa cultivars using 1H NMR spectroscopy and principal component analysis.
Topics: Asparagine; Cannabinoids; Cannabis; Dronabinol; Flowers; Glucose; Glutamic Acid; Magnetic Resonance Spectroscopy; Molecular Structure; Netherlands; Nuclear Magnetic Resonance, Biomolecular; Plant Leaves; Plants, Medicinal; Principal Component Analysis; Sucrose | 2004 |
Mutation in nucleotide-binding domains of sulfonylurea receptor 2 evokes Na-ATP-dependent activation of ATP-sensitive K+ channels: implication for dimerization of nucleotide-binding domains to induce channel opening.
Topics: Adenosine Triphosphate; Amino Acid Substitution; Animals; Asparagine; Aspartic Acid; ATP-Binding Cassette Transporters; Binding Sites; Dimerization; Glutamic Acid; Glutamine; Humans; Membrane Proteins; Mice; Mutation; Nicorandil; Nucleotides; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Structure, Tertiary; Receptors, Drug; Sodium; Sulfonylurea Receptors | 2004 |
Neurotransmitter amino acid in cerebrospinal fluid of patients with dementia with Lewy bodies.
Topics: Age Factors; Age of Onset; Aged; Asparagine; Aspartic Acid; Body Mass Index; Brain; Cerebrospinal Fluid; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Humans; Lewy Body Disease; Male; Neuropsychological Tests; Neurotransmitter Agents | 2005 |
Engineering of the pH optimum of Bacillus cereus beta-amylase: conversion of the pH optimum from a bacterial type to a higher-plant type.
Topics: Asparagine; Bacillus cereus; Bacterial Proteins; beta-Amylase; Binding Sites; Crystallography, X-Ray; Enzyme Activation; Glutamic Acid; Glycine max; Hydrogen-Ion Concentration; Kinetics; Maltose; Methionine; Mutagenesis, Site-Directed; Phenylalanine; Plant Proteins; Threonine; Tyrosine | 2004 |
Altered vulnerability to kainate excitotoxicity of transgenic-Cu/Zn SOD1 neurones.
Topics: Amyotrophic Lateral Sclerosis; Analysis of Variance; Animals; Asparagine; Calcium Channel Blockers; Cell Count; Cell Survival; Cells, Cultured; Cerebral Cortex; Cobalt; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Female; Glial Fibrillary Acidic Protein; Glutamic Acid; Immunohistochemistry; Kainic Acid; Male; Mice; Mice, Transgenic; Motor Neurons; Neurotoxins; Nifedipine; Phosphopyruvate Hydratase; Sodium Channel Blockers; Spinal Cord; Superoxide Dismutase; Tetrodotoxin; Time Factors | 2004 |
Kinetic analysis of the zinc-dependent deacetylase in the lipid A biosynthetic pathway.
Topics: Alanine; Amidohydrolases; Asparagine; Aspartic Acid; Bacterial Proteins; Glutamic Acid; Gram-Negative Bacteria; Histidine; Hydrogen-Ion Concentration; Kinetics; Lipid A; Lysine; Mutagenesis, Site-Directed; Substrate Specificity; Zinc | 2005 |
Active site rearrangement of the 2-hydrazinopyridine adduct in Escherichia coli amine oxidase to an azo copper(II) chelate form: a key role for tyrosine 369 in controlling the mobility of the TPQ-2HP adduct.
Topics: Amine Oxidase (Copper-Containing); Asparagine; Aspartic Acid; Azo Compounds; Binding Sites; Cations, Divalent; Chelating Agents; Cobalt; Copper; Crystallography, X-Ray; Enzyme Inhibitors; Enzyme Stability; Escherichia coli Proteins; Glutamic Acid; Hydrogen-Ion Concentration; Mutagenesis, Site-Directed; Phenylalanine; Pyridones; Resorcinols; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Spectrum Analysis, Raman; Tyrosine | 2005 |
Distinct conformation-mediated functions of an active site loop in the catalytic reactions of NAD-dependent D-lactate dehydrogenase and formate dehydrogenase.
Topics: Amino Acid Sequence; Asparagine; Base Sequence; Binding Sites; Catalytic Domain; Crystallography, X-Ray; Dose-Response Relationship, Drug; Formate Dehydrogenases; Glutamic Acid; Hydrogen Bonding; Kinetics; Lactate Dehydrogenases; Lactic Acid; Lactobacillus; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; NADP; Oxygen; Paracoccus; Protein Conformation; Sequence Homology, Amino Acid; Substrate Specificity; Thermodynamics | 2005 |
Hinge residue Ile260 of DNA polymerase beta is important for enzyme activity and fidelity.
Topics: Amino Acid Substitution; Animals; Arginine; Asparagine; Aspartic Acid; DNA Polymerase beta; Enzyme Activation; Enzyme Stability; Escherichia coli Proteins; Genetic Complementation Test; Genetic Variation; Glutamic Acid; Glutamine; Histidine; Isoleucine; Lysine; Peptide Fragments; Phenotype; Protein Folding; Protein Structure, Tertiary; Rats; Substrate Specificity | 2005 |
Overexpression and characterization of a novel chitinase from Trichoderma atroviride strain P1.
Topics: Acetylglucosamine; Amino Acid Sequence; Asparagine; Binding Sites; Catalytic Domain; Chitin; Chitinases; DNA; DNA Primers; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Glutamic Acid; Hydrogen-Ion Concentration; Hydrolysis; Hymecromone; Kinetics; Molecular Sequence Data; Protein Binding; Protein Folding; Protein Sorting Signals; Protein Structure, Tertiary; Recombinant Proteins; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Time Factors; Trichoderma | 2005 |
Point mutations at the type I Cu ligands, Cys457 and Met467, and at the putative proton donor, Asp105, in Myrothecium verrucaria bilirubin oxidase and reactions with dioxygen.
Topics: Alanine; Amino Acid Substitution; Asparagine; Aspartic Acid; Copper; Cysteine; Dithionite; Fungal Proteins; Glutamic Acid; Glutamine; Hypocreales; Ligands; Methionine; Oxidation-Reduction; Oxidoreductases Acting on CH-CH Group Donors; Oxygen; Point Mutation; Protons; Serine | 2005 |
Analysis of active site residues of botulinum neurotoxin E by mutational, functional, and structural studies: Glu335Gln is an apoenzyme.
Topics: Alanine; Apoenzymes; Arginine; Asparagine; Binding Sites; Botulinum Toxins; Catalysis; Crystallization; Enzyme Activation; Glutamic Acid; Glutamine; Kinetics; Mutagenesis, Site-Directed; Neprilysin; Neurotoxins; Protease Inhibitors; Substrate Specificity; Thermolysin; Threonine; Tyrosine | 2005 |
Characterization of salt-tolerant glutaminase from Stenotrophomonas maltophilia NYW-81 and its application in Japanese soy sauce fermentation.
Topics: Amino Acid Sequence; Asparagine; Aspergillus oryzae; Chromatography, Gel; DNA, Bacterial; DNA, Ribosomal; Electrophoresis, Polyacrylamide Gel; Enzyme Stability; Escherichia coli; Fermentation; Glutamic Acid; Glutaminase; Glutamine; Hydrogen-Ion Concentration; Micrococcus luteus; Molecular Sequence Data; Molecular Weight; Pseudomonas; Saline Solution, Hypertonic; Soy Foods; Stenotrophomonas maltophilia; Substrate Specificity; Temperature | 2005 |
Change in content of sugars and free amino acids in potato tubers under short-term storage at low temperature and the effect on acrylamide level after frying.
Topics: Acrylamide; Amino Acids; Asparagine; Aspartic Acid; Carbohydrate Metabolism; Chromatography, High Pressure Liquid; Cold Temperature; Color; Cooking; Food Handling; Food Preservation; Fructose; Glucose; Glutamic Acid; Glutamine; Solanum tuberosum; Time Factors | 2005 |
Expression, crystallization, and three-dimensional structure of the catalytic domain of human plasma kallikrein.
Topics: Amino Acid Sequence; Animals; Asparagine; Baculoviridae; Binding Sites; Catalysis; Crystallization; Crystallography, X-Ray; Electrophoresis, Polyacrylamide Gel; Gene Expression; Genetic Vectors; Glutamic Acid; Glycoside Hydrolases; Glycosylation; Humans; Hydrogen Bonding; Models, Molecular; Molecular Sequence Data; Molecular Structure; Mutagenesis; Pichia; Plasma Kallikrein; Protein Conformation; Recombinant Proteins; Serine Proteinase Inhibitors; Spodoptera; Transfection; Trypsin | 2005 |
Two rings of negative charges in the cytosolic vestibule of type-1 ryanodine receptor modulate ion fluxes.
Topics: Amino Acid Motifs; Animals; Asparagine; Biophysical Phenomena; Biophysics; Calcium; Cations; Cell Line; Cytosol; DNA, Complementary; Glutamic Acid; Glutamine; Humans; Ions; Kinetics; Lipid Bilayers; Models, Molecular; Muscle, Skeletal; Mutation; Neomycin; Potassium; Rabbits; Ryanodine; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum | 2006 |
Exchange of glutamine-217 to glutamate of Clostridium limosum exoenzyme C3 turns the asparagine-specific ADP-ribosyltransferase into an arginine-modifying enzyme.
Topics: ADP Ribose Transferases; Amino Acid Sequence; Arginine; Asparagine; Botulinum Toxins; Clostridium; Escherichia coli; Glutamic Acid; Glutamine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Recombinant Proteins; Sequence Homology, Amino Acid; Structure-Activity Relationship; Substrate Specificity; Trypsin Inhibitor, Bowman-Birk Soybean | 2006 |
Asparagine depletion after pegylated E. coli asparaginase treatment and induction outcome in children with acute lymphoblastic leukemia in first bone marrow relapse: a Children's Oncology Group study (CCG-1941).
Topics: Antibody Formation; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Asparagine; Child; Female; Glutamic Acid; Humans; Injections, Intramuscular; Male; Polyethylene Glycols; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction; Statistics, Nonparametric | 2006 |
Asparagine 706 and glutamate 183 at the catalytic site of sarcoplasmic reticulum Ca2+-ATPase play critical but distinct roles in E2 states.
Topics: Adenosine Triphosphate; Animals; Asparagine; Binding Sites; Calcium; Calcium-Transporting ATPases; Catalytic Domain; Enzyme Activation; Enzyme Inhibitors; Fluorides; Glutamic Acid; Hydrolysis; Kinetics; Mutagenesis, Site-Directed; Phosphates; Point Mutation; Protein Binding; Protein Conformation; Rabbits; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Vanadates | 2006 |
Engineering of the pH-dependence of thermolysin activity as examined by site-directed mutagenesis of Asn112 located at the active site of thermolysin.
Topics: Amino Acid Substitution; Asparagine; Binding Sites; Caseins; Catalysis; Electrophoresis, Polyacrylamide Gel; Glutamic Acid; Histamine; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Metalloendopeptidases; Mutagenesis, Site-Directed; Mutant Proteins; Protein Engineering; Protein Structure, Secondary; Structure-Activity Relationship; Substrate Specificity; Thermodynamics; Thermolysin; Zinc | 2006 |
Considerations on the lactate consumption by CHO cells in the presence of galactose.
Topics: Alanine; Animals; Asparagine; Bioreactors; Carbohydrate Metabolism; Cell Culture Techniques; Cell Survival; CHO Cells; Cricetinae; Culture Media; Galactose; Gluconeogenesis; Glucose; Glutamic Acid; Lactic Acid; Models, Biological; Serine | 2006 |
Catalytic site modifications of TAP1 and TAP2 and their functional consequences.
Topics: Amino Acid Substitution; Asparagine; Aspartic Acid; ATP Binding Cassette Transporter, Subfamily B, Member 2; ATP Binding Cassette Transporter, Subfamily B, Member 3; ATP-Binding Cassette Transporters; Baculoviridae; Binding Sites; Catalytic Domain; Cell Line, Tumor; Genetic Vectors; Glutamic Acid; Glutamine; Histidine; Humans; Nucleotides; Protein Transport | 2006 |
Of folding and function: understanding active-site context through metalloenzyme design.
Topics: Alanine; Amino Acid Sequence; Asparagine; Aspartic Acid; Binding Sites; Calcium; Circular Dichroism; DNA; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; Glutamic Acid; Helix-Turn-Helix Motifs; Hydrolysis; Kinetics; Lanthanoid Series Elements; Metalloproteins; Molecular Sequence Data; Phosphates; Protein Folding; Substrate Specificity | 2006 |
Conformational coupling between the cytoplasmic carboxylic acid and the retinal in a fungal light-driven proton pump.
Topics: Amino Acid Substitution; Ascomycota; Asparagine; Aspartic Acid; Carboxylic Acids; Cytoplasm; Glutamic Acid; Lasers; Neurospora; Protein Conformation; Proton Pumps; Retinaldehyde; Rhodopsin | 2006 |
Structure-function relationships of the viral RNA-dependent RNA polymerase: fidelity, replication speed, and initiation mechanism determined by a residue in the ribose-binding pocket.
Topics: Animals; Asparagine; Bacteriophages; Binding Sites; Glutamic Acid; HeLa Cells; Humans; Kinetics; Mutation; Nucleotides; Poliovirus; RNA-Dependent RNA Polymerase; Sequence Homology, Amino Acid; Structure-Activity Relationship; Substrate Specificity; Viral Proteins; Virus Replication | 2007 |
Structural basis of the catalytic reaction mechanism of novel 1,2-alpha-L-fucosidase from Bifidobacterium bifidum.
Topics: alpha-L-Fucosidase; Amino Acid Sequence; Asparagine; Bifidobacterium; Catalysis; Catalytic Domain; Crystallography, X-Ray; Glutamic Acid; Kinetics; Models, Molecular; Molecular Conformation; Molecular Sequence Data; Protein Conformation; Protein Structure, Tertiary; Substrate Specificity | 2007 |
Expected and unexpected effects of amino acid substitutions on polypeptide-directed crystal growth.
Topics: Amino Acid Sequence; Amino Acid Substitution; Asparagine; Calcification, Physiologic; Calcium; Crystallization; Glutamic Acid; Microscopy, Electron, Scanning; Minerals; Molecular Sequence Data; Peptides; Protein Structure, Secondary | 2007 |
Effect of amino acids and antibodies against nerve growth factor receptors on the development of organotypic culture of lymphoid tissue.
Topics: Amino Acids; Animals; Antibodies, Monoclonal; Asparagine; Cell Proliferation; Glutamic Acid; Lymphoid Tissue; Lysine; Organ Culture Techniques; Rats; Rats, Wistar; Receptors, Nerve Growth Factor; Spleen | 2007 |
A minor beta-structured conformation is the active state of a fusion peptide of vesicular stomatitis virus glycoprotein.
Topics: Amino Acid Sequence; Asparagine; Circular Dichroism; Glutamic Acid; Glycoproteins; Hydrogen-Ion Concentration; Liposomes; Micelles; Models, Chemical; Molecular Conformation; Molecular Sequence Data; Molecular Weight; Nuclear Magnetic Resonance, Biomolecular; Peptides; Phosphatidylcholines; Phosphatidylserines; Protein Structure, Secondary; Sodium Dodecyl Sulfate; Tyrosine; Valine; Vesicular stomatitis Indiana virus | 2008 |
Structural and mechanistic analysis of trichodiene synthase using site-directed mutagenesis: probing the catalytic function of tyrosine-295 and the asparagine-225/serine-229/glutamate-233-Mg2+B motif.
Topics: Amino Acid Motifs; Asparagine; Biochemistry; Carbon-Carbon Lyases; Catalytic Domain; Crystallography, X-Ray; Escherichia coli; Fusarium; Glutamic Acid; Kinetics; Magnesium; Models, Chemical; Mutagenesis, Site-Directed; Serine; Tyrosine | 2008 |
Structural basis for catalysis by onconase.
Topics: Adenosine Monophosphate; Alanine; Amino Acid Sequence; Amino Acid Substitution; Asparagine; Binding Sites; Catalysis; Crystallography, X-Ray; Disulfides; Glutamic Acid; Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; K562 Cells; Kinetics; Lysine; Models, Biological; Models, Chemical; Models, Molecular; Molecular Sequence Data; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Protein Synthesis Inhibitors; Ribonucleases; Sequence Homology, Amino Acid; Substrate Specificity; X-Ray Diffraction | 2008 |
Experimental and theoretical studies of sodium cation complexes of the deamidation and dehydration products of asparagine, glutamine, aspartic acid, and glutamic acid.
Topics: Amides; Amino Acids; Asparagine; Aspartic Acid; Glutamic Acid; Glutamine; Kinetics; Models, Chemical; Sodium; Thermodynamics; Water | 2008 |
Structural basis for the NAD-hydrolysis mechanism and the ARTT-loop plasticity of C3 exoenzymes.
Topics: ADP Ribose Transferases; Amino Acid Substitution; Asparagine; Binding Sites; Botulinum Toxins; Crystallography, X-Ray; Glutamic Acid; Hydrolysis; Mutation; NAD; Protein Conformation | 2008 |
Post-translational modification of cellular proteins during Leishmania donovani differentiation.
Topics: Animals; Asparagine; Aspartic Acid; Cell Differentiation; Chromatography, Liquid; Glutamic Acid; Glycosylation; Histidine; Humans; Leishmania donovani; Macrophages; Mass Spectrometry; Phosphorylation; Protein Processing, Post-Translational; Proteomics | 2008 |
An amino acid at position 142 in nitrilase from Rhodococcus rhodochrous ATCC 33278 determines the substrate specificity for aliphatic and aromatic nitriles.
Topics: Amino Acid Sequence; Amino Acids; Aminohydrolases; Arginine; Asparagine; Aspartic Acid; Catalysis; Glutamic Acid; Kinetics; Molecular Sequence Data; Molecular Weight; Mutagenesis, Site-Directed; Nitriles; Rhodococcus; Sequence Alignment; Substrate Specificity | 2008 |
A hydrogen bond in loop A is critical for the binding and function of the 5-HT3 receptor.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Asparagine; Binding Sites; Glutamic Acid; Hydrogen Bonding; Ligands; Mice; Models, Biological; Models, Chemical; Molecular Sequence Data; Protein Binding; Protein Structure, Tertiary; Receptors, Serotonin, 5-HT3 | 2008 |
Disruption of agonist and ligand activity in an AMPA glutamate receptor splice-variable domain deletion mutant.
Topics: Alanine; Amino Acid Sequence; Animals; Asparagine; Cells, Cultured; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Larva; Leucine; Ligands; Membrane Potentials; Microinjections; Oocytes; Patch-Clamp Techniques; Protein Structure, Tertiary; Receptors, AMPA; Sequence Deletion; Threonine; Xenopus | 2008 |
Comparison of nitrogen narcosis and helium pressure effects on striatal amino acids: a microdialysis study in rats.
Topics: Amino Acids; Animals; Asparagine; Aspartic Acid; Corpus Striatum; Glutamic Acid; Glutamine; Helium; Inert Gas Narcosis; Male; Microdialysis; Nitrogen; Pressure; Rats; Rats, Sprague-Dawley | 2009 |
An isocratic fluorescence HPLC assay for the monitoring of l-asparaginase activity and l-asparagine depletion in children receiving E. colil-asparaginase for the treatment of acute lymphoblastic leukaemia.
Topics: Adolescent; Antineoplastic Agents; Asparaginase; Asparagine; Aspartic Acid; Child; Child, Preschool; Chromatography, High Pressure Liquid; Drug Stability; Escherichia coli Proteins; Fluorescence; Glutamic Acid; Glutamine; Homoserine; Humans; Least-Squares Analysis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Reference Standards; Reproducibility of Results; Sensitivity and Specificity | 2009 |
Human caspase-3 inhibition by Z-tLeu-Asp-H: tLeu(P2) counterbalances Asp(P4) and Glu(P3) specific inhibitor truncation.
Topics: Amino Acid Sequence; Apoptosis; Asparagine; Caspase Inhibitors; Cell Line, Tumor; Cysteine Proteinase Inhibitors; Dipeptides; Glutamic Acid; Humans; Leucine; Molecular Structure | 2008 |
The metabolism of peptides of asparagine.
Topics: Asparagine; Glutamic Acid; Metabolism; Peptides | 1948 |
Effect of amino acids on cell proliferation and protein p53 expression in organotypic culture of lymphoid tissue from neonatal rats.
Topics: Aging; Amino Acids; Animals; Animals, Newborn; Arginine; Asparagine; Cell Differentiation; Cell Proliferation; Down-Regulation; Glutamic Acid; Lymphocyte Activation; Lymphoid Tissue; Lysine; Organ Culture Techniques; Rats; Rats, Wistar; Spleen; T-Lymphocytes; Tumor Suppressor Protein p53; Up-Regulation | 2008 |
Structural elucidation of the Cys-His-Glu-Asn proteolytic relay in the secreted CHAP domain enzyme from the human pathogen Staphylococcus saprophyticus.
Topics: Asparagine; Bacterial Proteins; Catalytic Domain; Cysteine; Endopeptidases; Glutamic Acid; Histidine; Magnetic Resonance Spectroscopy; Protein Structure, Tertiary; Staphylococcus | 2009 |
Analyzing the catalytic role of Asp97 in the methionine aminopeptidase from Escherichia coli.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Aminopeptidases; Asparagine; Aspartic Acid; Catalysis; Catalytic Domain; Escherichia coli; Escherichia coli Proteins; Glutamic Acid; Glycine; Kinetics; Methionine; Methionyl Aminopeptidases; Models, Molecular; Molecular Conformation; Molecular Sequence Data; Recombinant Proteins; Sequence Alignment; Substrate Specificity | 2008 |
Evaluation of the number of ionogenic groups of inulinase by acid-base titration.
Topics: Asparagine; Aspergillus; Fungal Proteins; Glutamic Acid; Glycoside Hydrolases; Histidine; Hydrogen-Ion Concentration; Lysine; Protein Denaturation; Serine; Tyrosine | 2008 |
Incorporating structural characteristics for identification of protein methylation sites.
Topics: Arginine; Asparagine; Binding Sites; Computer Simulation; Glutamic Acid; Lysine; Methylation; Protein Conformation; Proteins; Surface Properties | 2009 |
Effective amino acid composition of seaweeds inducing food preference behaviors in Aplysia kurodai.
Topics: Amino Acids; Animals; Aplysia; Asparagine; Aspartic Acid; Eating; Food Preferences; Glutamic Acid; Glutamine; Jaw; Phaeophyceae; Phenylalanine; Rhodophyta; Taste; Taurine; Ulva | 2009 |
Toxic effect of melanoidins from glucose-asparagine on trypsin activity.
Topics: Asparagine; Glucose; Glutamic Acid; Kinetics; Molecular Weight; Polymers; Trypsin | 2009 |
Role of intramembrane polar residues in the YgfO xanthine permease: HIS-31 and ASN-93 are crucial for affinity and specificity, and ASP-304 and GLU-272 are irreplaceable.
Topics: Amino Acid Substitution; Asparagine; Aspartic Acid; Escherichia coli K12; Escherichia coli Proteins; Evolution, Molecular; Glutamic Acid; Histidine; Membrane Transport Proteins; Models, Biological; Mutation, Missense; Nucleobase Transport Proteins; Protein Structure, Secondary; Substrate Specificity; Xanthine | 2009 |
Shifting unoccupied spectral space in mass spectrum of peptide fragment ions.
Topics: 1-Butanol; Amino Acid Sequence; Animals; Asparagine; Cattle; Chickens; Chromatography, Liquid; Esterification; Glutamic Acid; Ions; Mass Spectrometry; Molecular Sequence Data; Peptide Fragments; Protein Structure, Secondary; Sensitivity and Specificity; Tandem Mass Spectrometry | 2009 |
How can an inert gas counterbalance a NMDA-induced glutamate release?
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Asparagine; Aspartic Acid; Catheters, Indwelling; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Excitatory Amino Acid Agonists; Glutamic Acid; Glutamine; Homovanillic Acid; Inert Gas Narcosis; Male; Microdialysis; N-Methylaspartate; Nitrogen; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Statistics, Nonparametric | 2009 |
Structural and biochemical evidence that a TEM-1 beta-lactamase N170G active site mutant acts via substrate-assisted catalysis.
Topics: Amino Acid Sequence; Amino Acid Substitution; Ampicillin; Anti-Bacterial Agents; Asparagine; beta-Lactamases; Catalysis; Catalytic Domain; Cephalexin; Cephalothin; Crystallography, X-Ray; Escherichia coli; Glutamic Acid; Kinetics; Microbial Sensitivity Tests; Models, Molecular; Molecular Sequence Data; Molecular Structure; Mutagenesis, Site-Directed; Mutation; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Structure-Activity Relationship; Substrate Specificity | 2009 |
Embryo and larva development in common dentex (Dentex dentex), a pelagophil teleost: the quantitative composition of egg-free amino acids and their interrelations.
Topics: Amino Acids; Animals; Arginine; Asparagine; Embryonic Development; Female; Glutamic Acid; Glutamine; Larva; Male; Oocytes; Perciformes | 2010 |
A pressurized nitrogen counterbalance to cortical glutamatergic pathway stimulation.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Asparagine; Aspartic Acid; Baclofen; Corpus Striatum; Dopamine; Glutamic Acid; Glutamine; Homovanillic Acid; Hyperbaric Oxygenation; Inert Gas Narcosis; Male; Nitrogen; Pressure; Rats; Rats, Sprague-Dawley | 2010 |
Glutamine-linked and non-consensus asparagine-linked oligosaccharides present in human recombinant antibodies define novel protein glycosylation motifs.
Topics: Antibodies, Monoclonal; Asparagine; Glutamic Acid; Glycosylation; Humans; Immunoglobulin G; Models, Molecular; Oligosaccharides; Protein Modification, Translational; Recombinant Proteins | 2010 |
Acquisition of Raman spectra of amino acids using portable instruments: outdoor measurements and comparison.
Topics: Alanine; Amino Acids; Asparagine; Aspartic Acid; beta-Alanine; Glutamic Acid; Glutamine; Glycine; Methionine; Proline; Research Design; Robotics; Serine; Spectrum Analysis, Raman; Transportation; Tryptophan; Tyrosine; Workplace | 2010 |
Stripe-like increase of rCBV beyond the visible border of glioblastomas: site of tumor infiltration growing after neurosurgery.
Topics: Adult; Aged; Asparagine; Blood Volume; Brain Neoplasms; Cerebrovascular Circulation; Contrast Media; Creatine; Female; Glioblastoma; Glutamic Acid; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neurosurgical Procedures; Postoperative Complications; Reproducibility of Results; Statistics, Nonparametric; Time Factors; Tritium; Young Adult | 2011 |
Agonist-specific requirement for a glutamate in transmembrane helix 1 of the oxytocin receptor.
Topics: Amino Acid Sequence; Amino Acid Substitution; Arginine; Asparagine; Binding Sites; Cell Line; Enzyme-Linked Immunosorbent Assay; Glutamic Acid; Humans; Membrane Proteins; Models, Molecular; Mutation; Oxytocin; Protein Binding; Protein Structure, Secondary; Receptors, Oxytocin; Signal Transduction | 2011 |
A QM/QM investigation of the hUNG2 reaction surface: the untold tale of a catalytic residue.
Topics: Asparagine; Aspartic Acid; Catalysis; Catalytic Domain; Computer Simulation; DNA Mutational Analysis; Glutamic Acid; Histidine; Humans; Models, Molecular; Proline; Protons; Quantum Theory; Static Electricity; Surface Properties; Uracil-DNA Glycosidase; Water | 2011 |
A negative feedback loop that limits the ectopic activation of a cell type-specific sporulation sigma factor of Bacillus subtilis.
Topics: Alleles; Amino Acid Sequence; Amino Acid Substitution; Asparagine; Bacillus subtilis; DNA-Directed RNA Polymerases; Feedback, Physiological; Gene Expression Regulation, Bacterial; Glutamic Acid; Molecular Sequence Data; Mutation; Sigma Factor; Spores, Bacterial | 2011 |
Molecular basis for the activation of a catalytic asparagine residue in a self-cleaving bacterial autotransporter.
Topics: Asparagine; Catalysis; Catalytic Domain; Cyclization; Escherichia coli; Escherichia coli Proteins; Glutamic Acid; Hydrogen Bonding; Models, Molecular; Molecular Dynamics Simulation; Protein Structure, Tertiary; Protons; Serine Endopeptidases; Static Electricity; Water | 2012 |
The effect of the Asp175Asn and Glu180Gly TPM1 mutations on actin-myosin interaction during the ATPase cycle.
Topics: Actins; Actomyosin; Adenosine Triphosphatases; Amino Acid Substitution; Animals; Asparagine; Aspartic Acid; Cardiomyopathy, Hypertrophic; Fluorescent Dyes; Glutamic Acid; Glycine; Humans; Muscle Contraction; Mutation; Myosin Subfragments; Naphthalenesulfonates; Peptide Fragments; Protein Structure, Secondary; Rabbits; Spectrometry, Fluorescence; Tropomyosin | 2012 |
Uptake of sulfate but not phosphate by Mycobacterium tuberculosis is slower than that for Mycobacterium smegmatis.
Topics: Arginine; Asparagine; Culture Media; Gene Deletion; Glutamic Acid; Mycobacterium smegmatis; Mycobacterium tuberculosis; Nitrates; Nitrogen; Phosphates; Porins; Sulfates | 2012 |
Asparagine and aspartic acid concentrations in bone marrow versus peripheral blood during Berlin-Frankfurt-Münster-based induction therapy for childhood acute lymphoblastic leukemia.
Topics: Adolescent; Adrenal Cortex Hormones; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Asparagine; Aspartic Acid; Bone Marrow; Child; Child, Preschool; Daunorubicin; Drug Administration Schedule; Female; Glutamic Acid; Glutamine; Humans; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Time Factors; Treatment Outcome; Vincristine | 2012 |
Role of side-edge site of sphingomyelinase from Bacillus cereus.
Topics: Amino Acid Sequence; Amino Acid Substitution; Asparagine; Aspartic Acid; Bacillus cereus; Bacterial Proteins; Erythrocyte Membrane; Glutamic Acid; Magnesium; Molecular Sequence Data; Phenylalanine; Sphingomyelin Phosphodiesterase | 2012 |
The flexibility of two tropomyosin mutants, D175N and E180G, that cause hypertrophic cardiomyopathy.
Topics: Actins; Amino Acid Substitution; Asparagine; Aspartic Acid; Calcium; Cardiomyopathy, Hypertrophic; Glutamic Acid; Glycine; Humans; Microscopy, Electron; Models, Chemical; Molecular Dynamics Simulation; Mutation; Myosins; Protein Structure, Secondary; Tropomyosin | 2012 |
Changes in the C/N balance caused by increasing external ammonium concentrations are driven by carbon and energy availabilities during ammonium nutrition in pea plants: the key roles of asparagine synthetase and anaplerotic enzymes.
Topics: Ammonium Compounds; Asparagine; Aspartate-Ammonia Ligase; Carbon; Energy Metabolism; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Light; Nitrogen; Pisum sativum; Polyamines | 2013 |
Two-codon T-box riboswitch binding two tRNAs.
Topics: Anticodon; Asparagine; Clostridium acetobutylicum; Glutamic Acid; Riboswitch; RNA, Bacterial; RNA, Transfer, Asn; RNA, Transfer, Glu | 2013 |
Deciphering the role of aspartate and prephenate aminotransferase activities in plastid nitrogen metabolism.
Topics: Asparagine; Aspartate Aminotransferases; Aspartic Acid; Chlorophyll; Gene Expression Regulation, Plant; Gene Silencing; Glutamic Acid; Lignin; Multigene Family; Nicotiana; Nitrogen; Phenylalanine; Plant Leaves; Plant Proteins; Plastids; Transaminases | 2014 |
Mycobacterial mistranslation is necessary and sufficient for rifampicin phenotypic resistance.
Topics: Amino Acid Sequence; Antibiotics, Antitubercular; Asparagine; Aspartic Acid; DNA-Directed RNA Polymerases; Drug Resistance, Bacterial; Glutamic Acid; Glutamine; Molecular Sequence Data; Mutation; Mycobacterium smegmatis; Phenotype; Protein Biosynthesis; Proteomics; Recombination, Genetic; Rifampin | 2014 |
Synergistic effect of androgen receptor (CAG repeat length) and endothelial nitric oxide synthase (Glu298Asp variant) gene polymorphisms on seminal parameters in men with idiopathic oligoasthenozoospermia.
Topics: Adolescent; Adult; Amino Acid Substitution; Asparagine; Asthenozoospermia; Case-Control Studies; Epistasis, Genetic; Glutamic Acid; Humans; Male; Middle Aged; Nitric Oxide Synthase Type III; Polymorphism, Single Nucleotide; Receptors, Androgen; Semen; Semen Analysis; Trinucleotide Repeat Expansion; Young Adult | 2014 |
Metal cation dependence of interactions with amino acids: bond dissociation energies of Rb(+) and Cs(+) to the acidic amino acids and their amide derivatives.
Topics: Asparagine; Aspartic Acid; Cations; Cesium; Computer Simulation; Entropy; Glutamic Acid; Glutamine; Kinetics; Models, Chemical; Potassium; Quantum Theory; Rubidium; Sodium; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Xenon | 2014 |
Effect of the replacement of aspartic acid/glutamic acid residues with asparagine/glutamine residues in RNase He1 from Hericium erinaceus on inhibition of human leukemia cell line proliferation.
Topics: Amino Acid Sequence; Amino Acid Substitution; Antineoplastic Agents; Asparagine; Aspartic Acid; Basidiomycota; Cell Proliferation; Glutamic Acid; Glutamine; HL-60 Cells; Humans; Hydrogen-Ion Concentration; Leukemia; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Conformation; Ribonucleases; Structure-Activity Relationship | 2015 |
Glutamate and asparagine cataplerosis underlie glutamine addiction in melanoma.
Topics: Asparagine; Cell Growth Processes; Glutamic Acid; Glutamine; Humans; Melanoma | 2015 |
S-Isovaline Contained in Meteorites, Induces Enantiomeric Excess in D,L-glutamic Acid During Recrystallization.
Topics: Asparagine; Chromatography, High Pressure Liquid; Crystallization; Evolution, Chemical; Glutamic Acid; Leucine; Meteoroids; Nitro Compounds; Stereoisomerism; Valine | 2015 |
Stable isotope studies reveal pathways for the incorporation of non-essential amino acids in Acyrthosiphon pisum (pea aphids).
Topics: Amino Acids; Animals; Aphids; Asparagine; Aspartic Acid; Buchnera; Carbon Isotopes; Glutamic Acid; Glutamine; Nitrogen; Nitrogen Isotopes; Symbiosis | 2015 |
Using Surface Scans for the Evaluation of Halogen Bonds toward the Side Chains of Aspartate, Asparagine, Glutamate, and Glutamine.
Topics: Amides; Amino Acids; Asparagine; Aspartic Acid; Carboxylic Acids; Crystallography, X-Ray; Drug Design; Glutamic Acid; Glutamine; Halogens; Models, Molecular; Molecular Conformation; Solvents | 2016 |
Identification of a Sgo2-Dependent but Mad2-Independent Pathway Controlling Anaphase Onset in Fission Yeast.
Topics: Anaphase; Anaphase-Promoting Complex-Cyclosome; Asparagine; Aurora Kinase B; Cell Cycle; Cell Cycle Proteins; Centromere; Cyclin B; Glutamic Acid; Kinetochores; Lysine; Nuclear Proteins; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Spindle Apparatus | 2017 |
A Critical Role of Glutamine and Asparagine γ-Nitrogen in Nucleotide Biosynthesis in Cancer Cells Hijacked by an Oncogenic Virus.
Topics: Asparagine; Aspartate Aminotransferases; Aspartic Acid; Cell Proliferation; Glutamate Dehydrogenase; Glutamic Acid; Glutaminase; Glutamine; Herpesvirus 8, Human; Humans; Metabolic Networks and Pathways; Neoplasms; Nitrogen; Nucleotides | 2017 |
Interaction of DCF1 with ATP1B1 induces impairment in astrocyte structural plasticity via the P38 signaling pathway.
Topics: Animals; Animals, Newborn; Asparagine; Astrocytes; Cells, Cultured; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Glutamic Acid; Hippocampus; Humans; Immunoprecipitation; MAP Kinase Signaling System; Membrane Proteins; Mice; Mice, Knockout; Nerve Tissue Proteins; Protein Interaction Domains and Motifs; Receptors, AMPA; RNA, Messenger; Signal Transduction; Sodium-Potassium-Exchanging ATPase | 2018 |
Photocycle of Sensory Rhodopsin II from Halobacterium salinarum (HsSRII): Mutation of D103 Accelerates M Decay and Changes the Decay Pathway of a 13-cis O-like Species.
Topics: Amino Acid Substitution; Asparagine; Aspartic Acid; Cold Temperature; Glutamic Acid; Halobacterium salinarum; Halorhodopsins; Hydrogen Bonding; Light; Mutation; Photochemical Processes; Photolysis; Sensory Rhodopsins; Spectroscopy, Fourier Transform Infrared | 2018 |
Effects of nitrogen combined with zinc application on glutamate, glutamine, aspartate and asparagine accumulation in two winter wheat cultivars.
Topics: Asparagine; Aspartic Acid; Glutamic Acid; Glutamine; Nitrogen; Triticum; Zinc | 2018 |
Altered Asparagine and Glutamate Homeostasis Precede Coronary Artery Disease and Type 2 Diabetes.
Topics: Aged; Aged, 80 and over; Asparagine; Case-Control Studies; Coronary Artery Disease; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Follow-Up Studies; Glutamic Acid; Homeostasis; Humans; Male; Middle Aged; Prodromal Symptoms | 2018 |
Aspartate deficiency limits peptidoglycan synthesis and sensitizes cells to antibiotics targeting cell wall synthesis in Bacillus subtilis.
Topics: Anti-Bacterial Agents; Asparagine; Aspartate Aminotransferases; Aspartic Acid; Bacillus subtilis; Cell Wall; Diaminopimelic Acid; Glutamic Acid; Peptidoglycan | 2018 |
Metabolic profiles of cysteine, methionine, glutamate, glutamine, arginine, aspartate, asparagine, alanine and glutathione in Streptococcus thermophilus during pH-controlled batch fermentations.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Culture Media; Cysteine; Fermentation; Glutamic Acid; Glutamine; Glutathione; Hydrogen-Ion Concentration; Metabolic Networks and Pathways; Metabolome; Methionine; Nitrogen; Streptococcus thermophilus | 2018 |
Alteration in NMDAR-related amino acids in first episode psychosis.
Topics: Asparagine; Chromatography, Liquid; Female; Glutamic Acid; Glutamine; Humans; Hydroxyproline; Male; Mass Spectrometry; Proline; Psychotic Disorders; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Serine; Young Adult | 2019 |
Metabolic fingerprinting reveals extensive consequences of GLS hyperactivity.
Topics: Asparagine; Cell Line, Tumor; Glutamic Acid; Glutaminase; Glutamine; Glutathione; HEK293 Cells; Humans; Mass Spectrometry; Metabolic Networks and Pathways; Proline | 2020 |
Metabolomics approach revealed robust changes in amino acid and biogenic amine signatures in patients with schizophrenia in the early course of the disease.
Topics: Adult; Amino Acids; Antipsychotic Agents; Asparagine; Aspartic Acid; Biogenic Amines; Chromatography, Liquid; Early Diagnosis; Female; Glutamic Acid; Glutamine; Humans; Male; Metabolome; Metabolomics; Proline; Schizophrenia; Tandem Mass Spectrometry; Taurine; Young Adult | 2020 |
Structure of SRSF1 RRM1 bound to RNA reveals an unexpected bimodal mode of interaction and explains its involvement in SMN1 exon7 splicing.
Topics: Amino Acid Substitution; Asparagine; Computational Biology; Exons; Glutamic Acid; HEK293 Cells; Humans; Molecular Dynamics Simulation; Muscular Atrophy, Spinal; Nuclear Magnetic Resonance, Biomolecular; Protein Engineering; Recombinant Proteins; RNA Recognition Motif; RNA Splice Sites; RNA Splicing; Serine-Arginine Splicing Factors; Survival of Motor Neuron 1 Protein; Uridine | 2021 |
Gut bacterial gene changes following pegaspargase treatment in pediatric patients with acute lymphoblastic leukemia.
Topics: Antineoplastic Agents; Asparaginase; Asparagine; Aspartic Acid; Child; Genes, Bacterial; Glutamic Acid; Glutamine; Humans; Polyethylene Glycols; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2021 |
Structural basis of ketamine action on human NMDA receptors.
Topics: Antidepressive Agents; Asparagine; Binding Sites; Cryoelectron Microscopy; Glutamic Acid; Glycine; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Ketamine; Leucine; Molecular Dynamics Simulation; Nerve Tissue Proteins; Receptors, N-Methyl-D-Aspartate | 2021 |
Amino acids, microbiota-related metabolites, and the risk of incident diabetes among normoglycemic Chinese adults: Findings from the 4C study.
Topics: 2-Aminoadipic Acid; Adult; Alanine; Amino Acids; Asparagine; Diabetes Mellitus, Type 2; Glutamic Acid; Histidine; Homoserine; Humans; Lipids; Methionine; Microbiota; Proline; Uric Acid | 2022 |
Rapid, sensitive analysis method for determining the nitrogen stable isotope ratio of total free amino acids in soil.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cysteine; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Histidine; Leucine; Lysine; Nitrogen; Nitrogen Isotopes; Phenylalanine; Serine; Soil; Tryptophan | 2022 |
Targeted metabolomics combined with network pharmacology to reveal the protective role of luteolin in pulmonary arterial hypertension.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Arachidonic Acid; Asparagine; Butanes; Cell Proliferation; Dinoprost; Dinoprostone; Glutamic Acid; Humans; Leukotriene B4; Luteolin; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Network Pharmacology; Ornithine; Oxaloacetates; Prostaglandin D2; Pulmonary Arterial Hypertension; Rats | 2022 |
Wild soybean salt tolerance metabolic model: Assessment of storage protein mobilization in cotyledons and C/N balance in the hypocotyl/root axis.
Topics: Asparagine; Aspartic Acid; Carbon; Cotyledon; Fabaceae; Gene Expression Regulation, Plant; Glutamic Acid; Glycine max; Hypocotyl; Nitrogen; Plant Proteins; Salt Tolerance | 2023 |