glutamic acid has been researched along with 3-nitropropionic acid in 43 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 11 (25.58) | 18.2507 |
| 2000's | 30 (69.77) | 29.6817 |
| 2010's | 2 (4.65) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Allen, CN; Carpenter, DO; Hori, N; Ludolph, AC; Riepe, M; Spencer, PS | 1 |
| Fink, SL; Ho, DY; Lawrence, MS; Sapolsky, RM; Saydam, TC | 1 |
| Hassel, B; Sonnewald, U | 1 |
| Paul, SM; Weller, M | 1 |
| Erecińska, M; Nelson, D | 1 |
| Derr-Yellin, E; Nicklas, WJ; Zeevalk, GD | 1 |
| Fink, SL; Ho, DY; Sapolsky, RM | 1 |
| Aasly, J; Bakken, IJ; Johnsen, SF; Sonnewald, U; Unsgård, G; White, LR | 1 |
| Massieu, L; Sánchez-Carbente, MR | 1 |
| Blaszczak, P; Kleinrok, Z; Saran, T; Turski, WA; Urbanska, EM | 1 |
| Cheng, FC; Dryhurst, G; Han, J; Yang, Z | 1 |
| Brâthe, A; Hassel, B | 1 |
| Baba, H; Hida, H; Kumazaki, M; Nakajima, K; Nishino, H; Ooiwa, T; Shimano, Y; Shimizu, H | 1 |
| Butterfield, DA; Ersoz, A; Guo, Z; Mattson, MP | 1 |
| Gramsbergen, JB; Kornblit, BT; Storgaard, J; Zimmer, J | 1 |
| Brustovetsky, N; Brustovetsky, T; Dubinsky, JM | 1 |
| García, O; Massieu, L | 2 |
| Dutra-Filho, CS; Santos, CE; Souza, DO; Tasca, CI; Tavares, RG; Wajner, M | 1 |
| Del Río, P; Massieu, L; Montiel, T | 1 |
| Camarasa, J; Camins, A; Escubedo, E; Jiménez, A; Pallàs, M; Pubill, D; Rimbau, V; Verdaguer, E | 1 |
| Cattaneo, E; De Micheli, A; Goffredo, D; Matteoli, M; Rigamonti, D; Tartari, M; Verderio, C; Zuccato, C | 1 |
| Bloch, G; Brouillet, E; Hantraye, P; Henry, PG; Lebon, V; Vaufrey, F | 1 |
| Bondada, V; Geddes, JW; Gursahani, HI; Hadley, RW; Lee, J; Nasr, P; Pang, Z | 1 |
| Camins, A; Camps, P; Canudas, AM; Jiménez, A; Muñoz-Torrero, D; Pallàs, M; Pubill, D; Sureda, FX; Verdaguer, E | 1 |
| Bantubungi, K; Blum, D; Brouillet, E; Cuvelier, L; Galas, MC; Gall, D; Galluzzo, M; Ledent, C; Muller, CE; Pintor, A; Popoli, P; Rolland, AS; Schiffmann, SN | 1 |
| Bondada, V; Geddes, JW; Pang, Z; Sengoku, T; Siman, R | 1 |
| Beani, L; Bianchi, C; Hanau, S; Marti, M; Mela, F; Morari, M; Paganini, F; Stocchi, S; Ulazzi, L | 1 |
| Nakagawa, I; Nakase, H; Noriyama, Y; Ogawa, Y; Sakaki, T; Yamashita, M | 1 |
| Bernardi, G; Calabresi, P; Centonze, D; Gubellini, P; Gulino, A; Napolitano, M; Rossi, S; Spiezia, S | 1 |
| Bantubungi, K; Blum, D; Brotchi, J; Brouillet, E; Chtarto, A; Déglon, N; Galas, MC; Greco, A; Jacquard, C; Levivier, M; Minghetti, L; Pintor, A; Popoli, P; Schiffmann, SN; Tai, K; Tenenbaum, L | 1 |
| de Lago, E; Di Marzo, V; Fernández-Ruiz, J; Ramos, JA; Urbani, P | 1 |
| Baker, D; Cabranes, A; de Lago, E; Fernández-Ruiz, J; López-Rodríguez, M; Ortega-Gutiérrez, S; Pryce, G; Ramos, JA | 1 |
| Bahr, BA; Baude, AS; Brown, QB; Karanian, DA; Parsons, CG | 1 |
| Bernardi, G; Calabresi, P; Centonze, D; De Chiara, V; Mataluni, G; Picconi, B; Prosperetti, C; Rossi, S | 1 |
| Chagoya, V; Del Río, P; Massieu, L; Montiel, T | 1 |
| Decio, A; Fernández-Ruiz, J; Mechoulam, R; Ramos, JA; Sagredo, O | 1 |
| Smith, AJ; Smith, RA; Stone, TW | 1 |
| Akopian, G; Beal, MF; Cappelletti, M; Chow, R; Crawford, C; Gheorghe, SL; Jakowec, MW; Petzinger, GM; Reichel, CM; Walsh, JP; Zheng, L | 1 |
| Brunet, N; Calderó, J; Esquerda, JE; Tarabal, O | 1 |
| Smith, AJ; Smith, RA; Stone, TW; Tauskela, JS | 1 |
| Belcastro, V; Calabresi, P; Costa, C; Ientile, R; Luchetti, E; Picconi, B; Pisani, F; Siliquini, S; Tantucci, M; Tozzi, A | 1 |
| De la Rosa, G; Flores, G; Hernández-Echeagaray, E; Mendoza, E; Miranda-Barrientos, JA; Morales-Herrera, E; Ruelas, A; Vázquez-Roque, RA | 1 |
43 other study(ies) available for glutamic acid and 3-nitropropionic acid
| Article | Year |
|---|---|
Inhibition of energy metabolism by 3-nitropropionic acid activates ATP-sensitive potassium channels.
Topics: Adenosine Triphosphate; Animals; Energy Metabolism; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Nitro Compounds; Potassium Channels; Propionates; Rats; Rats, Inbred Strains | 1992 |
Defective herpes simplex virus vectors expressing the rat brain glucose transporter protect cultured neurons from necrotic insults.
Topics: Animals; Brain; Chlorocebus aethiops; Defective Viruses; Gene Expression; Genetic Vectors; Glutamic Acid; Hypoglycemia; Monosaccharide Transport Proteins; Necrosis; Neurons; Neurotoxins; Nitro Compounds; Promoter Regions, Genetic; Propionates; Rats; Rats, Sprague-Dawley; Simplexvirus; Vero Cells | 1995 |
Selective inhibition of the tricarboxylic acid cycle of GABAergic neurons with 3-nitropropionic acid in vivo.
Topics: Amino Acids; Animals; Brain; Carbon Isotopes; Citric Acid Cycle; Female; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Mice; Neurons; Nitro Compounds; Propionates; Succinate Dehydrogenase; Succinates; Succinic Acid | 1995 |
3-Nitropropionic acid is an indirect excitotoxin to cultured cerebellar granule neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cells, Cultured; Cerebellum; Cytoplasmic Granules; Dizocilpine Maleate; Electrophysiology; Glutamates; Glutamic Acid; Neurons; Neurotoxins; Nitro Compounds; Propionates; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1993 |
Effects of 3-nitropropionic acid on synaptosomal energy and transmitter metabolism: relevance to neurodegenerative brain diseases.
Topics: Adenosine Triphosphate; Animals; Brain Diseases; Cell Death; Creatine; Energy Metabolism; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Guanosine Diphosphate; Guanosine Triphosphate; Lactates; Lactic Acid; Male; Neurotransmitter Agents; Nitro Compounds; Oxygen Consumption; Phosphocreatine; Propionates; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Synaptosomes | 1994 |
Relative vulnerability of dopamine and GABA neurons in mesencephalic culture to inhibition of succinate dehydrogenase by malonate and 3-nitropropionic acid and protection by NMDA receptor blockade.
Topics: Animals; Cells, Cultured; Dopamine; Enzyme Inhibitors; gamma-Aminobutyric Acid; Glutamic Acid; Malonates; Mesencephalon; Neurons; Nitro Compounds; Propionates; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Succinate Dehydrogenase | 1995 |
Energy and glutamate dependency of 3-Nitropropionic acid neurotoxicity in culture.
Topics: Animals; Brain; Cells, Cultured; Corpus Striatum; Dose-Response Relationship, Drug; Energy Metabolism; Excitatory Amino Acid Antagonists; Glutamic Acid; Neurotoxins; Nitro Compounds; Propionates; Rats; Rats, Sprague-Dawley; Substrate Specificity | 1996 |
NMR spectroscopy study of the effect of 3-nitropropionic acid on glutamate metabolism in cultured astrocytes.
Topics: Animals; Animals, Newborn; Aspartic Acid; Astrocytes; Carbon Isotopes; Glutamic Acid; Lactates; Magnetic Resonance Spectroscopy; Mice; Neurotoxins; Nitro Compounds; Prefrontal Cortex; Propionates; Succinates | 1997 |
Transient inhibition of glutamate uptake in vivo induces neurodegeneration when energy metabolism is impaired.
Topics: Animals; Antihypertensive Agents; Aspartic Acid; Biological Transport; Brain Chemistry; Corpus Striatum; Dicarboxylic Acids; Energy Metabolism; Glutamic Acid; Hippocampus; Male; Microdialysis; Nerve Degeneration; Neurotoxins; Neurotransmitter Uptake Inhibitors; Nitro Compounds; Propionates; Pyrrolidines; Rats; Rats, Wistar | 1999 |
AMPA/kainate-related mechanisms contribute to convulsant and proconvulsant effects of 3-nitropropionic acid.
Topics: Animals; Anticonvulsants; Behavior, Animal; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Injections, Intraventricular; Male; Mice; Mitochondria; N-Methylaspartate; Nitro Compounds; Propionates; Quinoxalines; Receptors, AMPA | 1999 |
Inhibitors of mitochondrial respiration, iron (II), and hydroxyl radical evoke release and extracellular hydrolysis of glutathione in rat striatum and substantia nigra: potential implications to Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Corpus Striatum; Cysteine; Glutamic Acid; Glutathione; Glycine; Hydrolysis; Hydroxyl Radical; Iron; Kinetics; Male; Microdialysis; Mitochondria; Models, Chemical; Nitro Compounds; Oxygen Consumption; Parkinson Disease; Perfusion; Propionates; Rats; Rats, Sprague-Dawley; Substantia Nigra | 1999 |
Neuronal pyruvate carboxylation supports formation of transmitter glutamate.
Topics: Animals; Aspartic Acid; Astrocytes; Bicarbonates; Carbon Radioisotopes; Cells, Cultured; Cerebellum; Citrate (si)-Synthase; Citric Acid Cycle; Fumarate Hydratase; Glutamic Acid; Ketoglutarate Dehydrogenase Complex; Malate Dehydrogenase; Neurons; Neurotoxins; Nitro Compounds; Propionates; Pyruvates; Rats | 2000 |
The striatum is the most vulnerable region in the brain to mitochondrial energy compromise: a hypothesis to explain its specific vulnerability.
Topics: Animals; Antihypertensive Agents; Apoptosis; Cerebral Arteries; Cerebral Cortex; Denervation; Dicarboxylic Acids; Dopamine; Energy Metabolism; Glutamic Acid; Male; Mitochondria; Motor Activity; Neostriatum; Neuroglia; Nitro Compounds; Propionates; Pyrrolidines; Rats; Rats, Wistar | 2000 |
Beneficial effects of dietary restriction on cerebral cortical synaptic terminals: preservation of glucose and glutamate transport and mitochondrial function after exposure to amyloid beta-peptide, iron, and 3-nitropropionic acid.
Topics: Amyloid beta-Peptides; Animals; Biological Transport; Cerebral Cortex; Food Deprivation; Glucose; Glutamic Acid; Heat-Shock Proteins; Iron; Male; Mitochondria; Nitro Compounds; Oxidative Stress; Presynaptic Terminals; Propionates; Rats; Rats, Sprague-Dawley | 2000 |
3-Nitropropionic acid neurotoxicity in organotypic striatal and corticostriatal slice cultures is dependent on glucose and glutamate.
Topics: Animals; Aspartic Acid; Cells, Cultured; Cerebral Cortex; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Antagonists; Glucose; Glutamate Decarboxylase; Glutamic Acid; Huntington Disease; In Vitro Techniques; Mitochondria; Nitro Compounds; Propionates; Rats; Succinate Dehydrogenase; Tetrodotoxin | 2000 |
On the mechanisms of neuroprotection by creatine and phosphocreatine.
Topics: Animals; Cells, Cultured; Corpus Striatum; Creatine; Dietary Supplements; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Mitochondria; Neurons; Neuroprotective Agents; Nitro Compounds; Permeability; Phosphocreatine; Propionates; Rats; Rats, Sprague-Dawley | 2001 |
Strategies for neuroprotection against L-trans-2,4-pyrrolidine dicarboxylate-induced neuronal damage during energy impairment in vitro.
Topics: Animals; Cell Survival; Cells, Cultured; Cerebellum; Coloring Agents; Convulsants; Cyclic N-Oxides; Dicarboxylic Acids; Energy Metabolism; Enzyme Inhibitors; Glutamic Acid; Mitochondria; Neurons; Neuroprotective Agents; Neurotransmitter Uptake Inhibitors; Nitro Compounds; Nitrogen Oxides; Propionates; Pyrrolidines; Rats; Rats, Wistar; Sodium Azide; Tetrazolium Salts; Thiazoles; Vitamin E | 2001 |
Inhibition of glutamate uptake into synaptic vesicles from rat brain by 3-nitropropionic acid in vitro.
Topics: Adenosine Triphosphatases; Animals; Brain Chemistry; Dose-Response Relationship, Drug; Enzyme Activation; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Male; Neurotoxins; Nitro Compounds; Propionates; Rats; Rats, Wistar; Synaptic Vesicles | 2001 |
Neurotoxicity of glutamate uptake inhibition in vivo: correlation with succinate dehydrogenase activity and prevention by energy substrates.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Amino Acid Transport System X-AG; Animals; Brain Ischemia; Convulsants; Creatine; Dicarboxylic Acids; Drug Interactions; Energy Metabolism; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Neostriatum; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Neurotransmitter Uptake Inhibitors; Nitro Compounds; Propionates; Pyrrolidines; Pyruvic Acid; Rats; Rats, Wistar; Succinate Dehydrogenase | 2001 |
Evaluation of neuronal cell death by laser scanning cytometry.
Topics: Animals; Cell Culture Techniques; Cell Death; Cell Survival; Culture Media, Serum-Free; Cytophotometry; Dose-Response Relationship, Drug; Glutamic Acid; Image Processing, Computer-Assisted; Microscopy, Confocal; Microscopy, Fluorescence; Neurons; Neuropharmacology; Neurotoxins; Nitro Compounds; Potassium Deficiency; Propionates; Rats; Rats, Sprague-Dawley | 2002 |
Calcium-dependent cleavage of endogenous wild-type huntingtin in primary cortical neurons.
Topics: Animals; Blotting, Western; Brain; Calcimycin; Calcium; Calpain; Cell-Free System; Cells, Cultured; Densitometry; Glutamic Acid; Huntingtin Protein; Ionophores; Nerve Tissue Proteins; Neurons; Nitro Compounds; Nuclear Proteins; Propionates; Protein Binding; Rats; Rats, Sprague-Dawley; Time Factors | 2002 |
Decreased TCA cycle rate in the rat brain after acute 3-NP treatment measured by in vivo 1H-[13C] NMR spectroscopy.
Topics: Animals; Brain; Brain Chemistry; Carbon Isotopes; Citric Acid Cycle; Energy Metabolism; Glucose; Glutamic Acid; Infusions, Intravenous; Injections, Intraperitoneal; Ketoglutaric Acids; Magnetic Resonance Spectroscopy; Models, Biological; Monte Carlo Method; Nitro Compounds; Oxidation-Reduction; Propionates; Protons; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity | 2002 |
Influence of cytosolic and mitochondrial Ca2+, ATP, mitochondrial membrane potential, and calpain activity on the mechanism of neuron death induced by 3-nitropropionic acid.
Topics: Adenosine Triphosphate; Animals; Brain; Calcium; Cell Death; Cytosol; Dizocilpine Maleate; Female; Fetus; Glutamic Acid; In Vitro Techniques; Intracellular Membranes; Membrane Potentials; Mitochondria; Neurons; Neurotoxins; Nitro Compounds; Pregnancy; Propionates; Rats; Rats, Sprague-Dawley | 2003 |
Neuroprotective effects of (+/-)-huprine Y on in vitro and in vivo models of excitoxicity damage.
Topics: Aminoquinolines; Animals; Binding, Competitive; Calcium; Cell Death; Cells, Cultured; Cerebellum; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Gliosis; Glutamic Acid; Heat-Shock Proteins; Heterocyclic Compounds, 4 or More Rings; HSP27 Heat-Shock Proteins; Isoquinolines; Mice; Molecular Chaperones; Motor Activity; N-Methylaspartate; Neoplasm Proteins; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Neurotoxins; Nitro Compounds; Propionates; Rats | 2003 |
A dual role of adenosine A2A receptors in 3-nitropropionic acid-induced striatal lesions: implications for the neuroprotective potential of A2A antagonists.
Topics: Adenosine; Animals; Body Weight; Cell Death; Corpus Striatum; Disease Models, Animal; Drug Administration Schedule; Encephalitis; Genetic Predisposition to Disease; Glutamic Acid; Huntington Disease; Male; Mice; Mice, Knockout; Neuroprotective Agents; Nitro Compounds; Phenethylamines; Propionates; Rats; Rats, Inbred Lew; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Purinergic P1; RNA, Messenger; Signal Transduction; Survival Rate; Synapses; Xanthines | 2003 |
Calpain facilitates the neuron death induced by 3-nitropropionic acid and contributes to the necrotic morphology.
Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Calpain; Caspases; Cell Death; Cell Survival; Cells, Cultured; Cysteine Proteinase Inhibitors; Dizocilpine Maleate; Drug Synergism; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Immunoblotting; Immunohistochemistry; Necrosis; Neurons; Neurotoxins; Nitro Compounds; Oligopeptides; Propionates; Rats; Spectrin; Time Factors | 2003 |
Differential responsiveness of rat striatal nerve endings to the mitochondrial toxin 3-nitropropionic acid: implications for Huntington's disease.
Topics: Acetylcholine; Animals; Convulsants; Corpus Striatum; Dopamine; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Huntington Disease; Male; Mitochondria; Nitro Compounds; Organ Culture Techniques; Potassium Channels; Propionates; Rats; Rats, Sprague-Dawley; Riluzole; Sodium Channels; Succinate Dehydrogenase; Synaptosomes; Tetrodotoxin | 2003 |
Chemical preconditioning prevents paradoxical increase in glutamate release during ischemia by activating ATP-dependent potassium channels in gerbil hippocampus.
Topics: Adenosine Triphosphate; Animals; Brain Ischemia; Calcium; Diazoxide; Excitatory Postsynaptic Potentials; Gerbillinae; Glutamic Acid; Glyburide; Hippocampus; In Vitro Techniques; Neurotoxins; Nitro Compounds; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Propionates | 2003 |
Glutamate uptake inhibitor L-trans-pyrrolidine 2,4-dicarboxylate becomes neurotoxic in the presence of subthreshold concentrations of mitochondrial toxin 3-nitropropionate: involvement of mitochondrial reducing activity and ATP production.
Topics: Adenosine Triphosphate; Animals; Cells, Cultured; Cerebellum; Dicarboxylic Acids; Glutamic Acid; Mitochondria; Neurotransmitter Uptake Inhibitors; Nitro Compounds; Propionates; Pyrrolidines; Rats; Rats, Wistar | 2003 |
Inhibition of mitochondrial complex II alters striatal expression of genes involved in glutamatergic and dopaminergic signaling: possible implications for Huntington's disease.
Topics: Animals; Dopamine; Dopamine and cAMP-Regulated Phosphoprotein 32; Electron Transport Complex II; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Glutamic Acid; Huntington Disease; In Vitro Techniques; Neostriatum; Nerve Tissue Proteins; Nitro Compounds; Oligonucleotide Array Sequence Analysis; Phosphoproteins; Phosphoric Monoester Hydrolases; Propionates; Protein Serine-Threonine Kinases; Rats; Rats, Wistar; Signal Transduction; Succinate Dehydrogenase | 2004 |
Minocycline in phenotypic models of Huntington's disease.
Topics: Animals; Calpain; Caspases; Cell Death; Cells, Cultured; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Encephalitis; Glutamic Acid; Huntingtin Protein; Huntington Disease; Male; Minocycline; Nerve Degeneration; Nerve Tissue Proteins; Neuroprotective Agents; Nitro Compounds; Nuclear Proteins; Phenotype; Propionates; Quinolinic Acid; Rats; Rats, Inbred Lew; Rats, Wistar; Staurosporine | 2005 |
Arvanil, a hybrid endocannabinoid and vanilloid compound, behaves as an antihyperkinetic agent in a rat model of Huntington's disease.
Topics: Animals; Brain Chemistry; Capsaicin; Convulsants; Disease Models, Animal; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; Huntington Disease; Hyperkinesis; Male; Motor Activity; Nitro Compounds; Propionates; Rats; Rats, Sprague-Dawley | 2005 |
UCM707, an inhibitor of the anandamide uptake, behaves as a symptom control agent in models of Huntington's disease and multiple sclerosis, but fails to delay/arrest the progression of different motor-related disorders.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Arachidonic Acids; Brain Chemistry; Disease Models, Animal; Disease Progression; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Electrochemistry; Encephalomyelitis, Autoimmune, Experimental; Endocannabinoids; Exploratory Behavior; Furans; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Huntington Disease; Male; Malonates; Movement Disorders; Multiple Sclerosis; Nitro Compounds; Oxidopamine; Polyunsaturated Alkamides; Propionates; Rats; Rats, Sprague-Dawley; Time Factors; Tyrosine 3-Monooxygenase | 2006 |
3-Nitropropionic acid toxicity in hippocampus: protection through N-methyl-D-aspartate receptor antagonism.
Topics: Animals; Animals, Newborn; Cytoskeleton; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Memantine; Mitochondria; Nerve Degeneration; Neural Pathways; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Neurotoxins; Nitro Compounds; Organ Culture Techniques; Propionates; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission | 2006 |
Deficits of glutamate transmission in the striatum of toxic and genetic models of Huntington's disease.
Topics: Animals; Corpus Striatum; Disease Models, Animal; Excitatory Postsynaptic Potentials; Glutamic Acid; Huntington Disease; In Vitro Techniques; Male; Mice; Mice, Transgenic; Neurons; Nitro Compounds; Patch-Clamp Techniques; Propionates; Rats; Rats, Sprague-Dawley; Synaptic Transmission | 2006 |
Exacerbation of excitotoxic neuronal death induced during mitochondrial inhibition in vivo: relation to energy imbalance or ATP depletion?
Topics: Adenosine Triphosphate; Analysis of Variance; Animals; Cell Death; Corpus Striatum; Drug Synergism; Energy Metabolism; Glial Fibrillary Acidic Protein; Glutamic Acid; Lactic Acid; Male; Neurons; Neurotoxins; Nitro Compounds; Propionates; Rats; Rats, Wistar; Succinate Dehydrogenase; Time Factors | 2007 |
Cannabidiol reduced the striatal atrophy caused 3-nitropropionic acid in vivo by mechanisms independent of the activation of cannabinoid, vanilloid TRPV1 and adenosine A2A receptors.
Topics: Adenosine A2 Receptor Agonists; Animals; Arachidonic Acids; Atrophy; Brain Chemistry; Cannabidiol; Cannabinoid Receptor Agonists; Cannabinoids; Chromatography, High Pressure Liquid; Convulsants; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; In Situ Hybridization; Male; Neostriatum; Nitro Compounds; Phosphopyruvate Hydratase; Propionates; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; RNA, Messenger; TRPV Cation Channels | 2007 |
Preconditioning with NMDA protects against toxicity of 3-nitropropionic acid or glutamate in cultured cerebellar granule neurons.
Topics: Analysis of Variance; Animals; Animals, Newborn; Cell Survival; Cells, Cultured; Cerebellum; Convulsants; Dose-Response Relationship, Drug; Glutamic Acid; N-Methylaspartate; Neurons; Neuroprotective Agents; Nitro Compounds; Propionates; Rats; Rats, Sprague-Dawley; Time Factors | 2008 |
Decreased striatal dopamine release underlies increased expression of long-term synaptic potentiation at corticostriatal synapses 24 h after 3-nitropropionic-acid-induced chemical hypoxia.
Topics: Animals; Cerebral Cortex; Convulsants; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Agonists; Down-Regulation; Glutamic Acid; Hypoxia, Brain; Long-Term Potentiation; Male; Movement; Neural Pathways; Neurotoxins; Nitro Compounds; Propionates; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Species Specificity; Synaptic Transmission; Time Factors; Up-Regulation | 2008 |
Excitotoxic motoneuron degeneration induced by glutamate receptor agonists and mitochondrial toxins in organotypic cultures of chick embryo spinal cord.
Topics: Animals; Calcium Signaling; Chick Embryo; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Glutamic Acid; Kainic Acid; Malonates; Mitochondria; Motor Neuron Disease; Motor Neurons; N-Methylaspartate; Nerve Degeneration; Neuroprotective Agents; Neurotoxins; Nitro Compounds; Organ Culture Techniques; Propionates; Riluzole; Spinal Cord | 2009 |
Preconditioning with 4-aminopyridine protects cerebellar granule neurons against excitotoxicity.
Topics: 4-Aminopyridine; Animals; Bicuculline; Cell Death; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; GABA Antagonists; Glutamic Acid; N-Methylaspartate; Neurons; Neuroprotective Agents; Neurotoxins; Nitro Compounds; Propionates; Rats; Rats, Sprague-Dawley; Time Factors | 2009 |
Electrophysiological actions of zonisamide on striatal neurons: Selective neuroprotection against complex I mitochondrial dysfunction.
Topics: Action Potentials; Animals; Antioxidants; Bicuculline; Corpus Striatum; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; GABA Antagonists; Glucose; Glutamic Acid; In Vitro Techniques; Isoxazoles; Male; Neurons; Nitro Compounds; Propionates; Rats; Rats, Wistar; Rotenone; Uncoupling Agents; Zonisamide | 2010 |
In vivo mitochondrial inhibition alters corticostriatal synaptic function and the modulatory effects of neurotrophins.
Topics: Animals; Brain-Derived Neurotrophic Factor; Cerebral Cortex; Corpus Striatum; Glutamic Acid; Male; Mice, Inbred C57BL; Mitochondria; Mitochondrial Diseases; Nerve Growth Factors; Neural Pathways; Neurotrophin 3; Nitro Compounds; Propionates; Random Allocation; Receptors, Nerve Growth Factor; Synapses; Synaptic Transmission; Tissue Culture Techniques | 2014 |