Compounds > glutamic acid

glutamic acid and 3-cyano-n-(1,3-diphenyl-1h-pyrazol-5-yl)benzamide

glutamic acid has been researched along with 3-cyano-n-(1,3-diphenyl-1h-pyrazol-5-yl)benzamide in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Burno, M; Conn, PJ; Duggan, ME; Hartman, GD; Huff, JR; Kinney, GG; Leister, WH; Lemaire, W; Lindsley, CW; O'brien, JA; Pettibone, DJ; Smith, S; Sur, C; Tiller, PR; Williams, DL; Wisnoski, DD1
Bradley, SJ; Challiss, RA; Watson, JM1
Burns, AR; Hampson, DR; Roy, PJ; Tharmalingam, S1
Andrade, JN; Carvalho, TG; de Souza, JM; Dobransky, T; Doria, JG; Guatimosim, C; Guimaraes, IM; Ribeiro, FM; Rodrigues, HA1

Other Studies

4 other study(ies) available for glutamic acid and 3-cyano-n-(1,3-diphenyl-1h-pyrazol-5-yl)benzamide

ArticleYear
Discovery of positive allosteric modulators for the metabotropic glutamate receptor subtype 5 from a series of N-(1,3-diphenyl-1H- pyrazol-5-yl)benzamides that potentiate receptor function in vivo.
    Journal of medicinal chemistry, 2004, Nov-18, Volume: 47, Issue:24

    Topics: Allosteric Regulation; Animals; Antipsychotic Agents; Benzamides; Brain; CHO Cells; Cricetinae; Cricetulus; Glutamic Acid; Humans; In Vitro Techniques; Pyrazoles; Rats; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Reflex, Startle; Structure-Activity Relationship

2004
Effects of positive allosteric modulators on single-cell oscillatory Ca2+ signaling initiated by the type 5 metabotropic glutamate receptor.
    Molecular pharmacology, 2009, Volume: 76, Issue:6

    Topics: Allosteric Regulation; Animals; Benzamides; Calcium Compounds; Calcium Signaling; Cerebral Cortex; CHO Cells; Cricetinae; Cricetulus; Glutamic Acid; Hydrazines; Oxadiazoles; Oxides; Phthalimides; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate

2009
Orthosteric and allosteric drug binding sites in the Caenorhabditis elegans mgl-2 metabotropic glutamate receptor.
    Neuropharmacology, 2012, Volume: 63, Issue:4

    Topics: Animals; Benzamides; Binding Sites; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Calcium Signaling; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; GTP-Binding Proteins; HEK293 Cells; Humans; Kinetics; Ligands; Phylogeny; Protein Structure, Tertiary; Pyrazoles; Quisqualic Acid; Receptors, Metabotropic Glutamate; Recombinant Proteins; Sequence Homology, Amino Acid

2012
The mGluR5 positive allosteric modulator, CDPPB, ameliorates pathology and phenotypic signs of a mouse model of Huntington's disease.
    Neurobiology of disease, 2015, Volume: 73

    Topics: Age Factors; Animals; Benzamides; Cell Death; Cells, Cultured; Corpus Striatum; Disease Models, Animal; Embryo, Mammalian; Extracellular Signal-Regulated MAP Kinases; Glutamic Acid; Humans; Huntingtin Protein; Huntington Disease; Mice; Mice, Transgenic; Mitochondria; Motor Activity; Nerve Tissue Proteins; Neurons; Pyrazoles; Recognition, Psychology; Signal Transduction; Synapses

2015