glunicate and glucitol-hexanicotinate

glunicate has been researched along with glucitol-hexanicotinate* in 2 studies

Other Studies

2 other study(ies) available for glunicate and glucitol-hexanicotinate

ArticleYear
Some cardiovascular effects of LG 13979: comparison with nicotinic acid and other nicotinic acid derivatives.
    The Journal of pharmacy and pharmacology, 1983, Volume: 35, Issue:9

    Topics: Animals; Blood Pressure; Female; Flushing; Guinea Pigs; Heart Rate; Hemodynamics; Male; Niacin; Niacinamide; Niceritrol; Nicotinic Acids; Rabbits; Sorbitol

1983
Acute effects on plasma lipids in the rat of a new long-acting nicotinic acid derivative: LG 13979.
    The Journal of pharmacy and pharmacology, 1983, Volume: 35, Issue:9

    The effects on plasma lipids and nicotinic acid concentrations of a single dose of 2-(3-pyridinecarbonylamino)-2-deoxy-1,3,4,6 dihydrogen-D-glucose tetra-3-pyridinecarboxylate (LG 13979) compared with the effects of nicotinic acid and of its known derivatives niceritrol and sorbinicate, at the same doses, were studied in the fasted rat. Results show that LG 13979 has more prolonged activity on plasma free fatty acids and triglycerides, with longer lasting and more intense activity on plasma cholesterol than these three reference standards. Free fatty acid rebound occurs after administration of nicotinic acid and niceritrol, but not after LG 13979. This pharmacodynamic profile may be explained on the basis of the kinetics of nicotinic acid plasma concentrations, which are low, constant and lasting after LG 13979 administration.

    Topics: Animals; Cholesterol; Fatty Acids, Nonesterified; Kinetics; Lipids; Male; Niacinamide; Niceritrol; Nicotinic Acids; Rats; Rats, Inbred Strains; Sorbitol; Triglycerides

1983