glucuronic acid has been researched along with iduronate in 68 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (16.18) | 18.7374 |
| 1990's | 17 (25.00) | 18.2507 |
| 2000's | 19 (27.94) | 29.6817 |
| 2010's | 15 (22.06) | 24.3611 |
| 2020's | 6 (8.82) | 2.80 |
| Authors | Studies |
|---|---|
| De Ruiter, GA; Rombouts, FM; Schols, HA; Voragen, AG | 1 |
| Fransson, LA; Schmidtchen, A | 1 |
| Gettins, P; Horne, A | 1 |
| Humphries, DE; Palmer, ME; Silbert, CK; Silbert, JE | 1 |
| Sarkar, B; Whitfield, DM | 1 |
| Burd, DA; Garg, HG; Lippay, EW; Neame, PJ | 1 |
| Bossennec, V; Perly, B; Petitou, M | 1 |
| Antonopoulos, CA; Engfeldt, B; Hjerpe, A; Karamanos, NK; Tsegenidis, T | 1 |
| Mardiguian, J; Trillou, M | 1 |
| Endo, M; Majima, M; Nakamura, T | 1 |
| Danishefsky, I; Radoff, S; Rosenfeld, L | 1 |
| Danishefsky, I; Radoff, S | 1 |
| Grant, ME; Shuttleworth, CA; Smalley, JW | 1 |
| Endo, M; Igarashi, S; Majima, M; Matsue, H; Nakamura, T | 1 |
| Gallagher, JT; Gasiunas, N; Schor, SL | 1 |
| Beck, M; Glössl, J; Kresse, H; Rüter, R | 1 |
| Miyamoto, I; Nagase, S | 1 |
| Malmström, A | 1 |
| Cherchi, GM; Coinu, R; Formato, M; Senes, A; Soccolini, F | 1 |
| Endo, M; Harata, S; Nakamura, T; Narita, H; Takagaki, K; Takeda, Y | 1 |
| Bai, X; Esko, JD | 1 |
| Linhardt, RJ; Mayo, KH; Mikhailov, D; Pervin, A; Toida, T; Vlahov, IR | 1 |
| Bai, X; Bame, KJ; Esko, JD; Habuchi, H; Kimata, K | 1 |
| Embery, G; Hall, R; Rees, S; Rose, K; Shellis, P; Waddington, R | 1 |
| Kobayashi, M; Liu, J; Rosenberg, RD; Shworak, NW; Silbert, JE; Sugumaran, G | 1 |
| Castro, RA; Chavante, SF; Dietrich, CP; Fareed, J; Gorin, PA; Jeske, W; Mendes, A; Nader, HB; Paiva, JF | 1 |
| Bono, F; Duchaussoy, P; Herbert, JM; Kovensky, J; Petitou, M; Salmivirta, M; Sinaÿ, P; Sizun, P | 1 |
| Griep, JA; Longas, MO; Park, JI; Schoeneck, CD; Trinkle, JA | 1 |
| Hagner-Mcwhirter, A; Li, Jp; Lindahl, U | 1 |
| Endo, M; Kakizaki, I; Majima, M; Munakata, H; Takagaki, K | 1 |
| Eriksson, I; Kjellén, L; Pikas, DS | 1 |
| Lindahl, U; Safaiyan, F; Salmivirta, M | 1 |
| Anagnostides, ST; Papageorgacopoulou, N; Theocharis, DA; Tsiganos, CP; Vynios, DH | 1 |
| Hjerpe, A; Karamanos, NK; Lamari, F; Mitropoulou, TN; Syrokou, A | 1 |
| Chaidedgumjorn, A; Imanari, T; Sato, K; Sudo, M; Toida, T; Toyoda, H | 1 |
| Embery, G; Hughes, W; Rees, SG | 1 |
| Hagner-McWhirter, A; Li, JP; Lindahl, U; Oscarson, S | 1 |
| Boros, S; Kuszmann, J; Medgyes, G | 1 |
| Eriksson, I; Holmborn, K; Kjellén, L; Kusche-Gullberg, M; Ledin, J; Smeds, E | 1 |
| Akiyama-Nambu, F; Itoh, N; Mikami, T; Nandini, CD; Ohta, M; Sugahara, K | 1 |
| Feyerabend, TB; Li, JP; Lindahl, U; Rodewald, HR | 1 |
| Amster, IJ; Chi, L; Linhardt, RJ; Wolff, JJ | 1 |
| Li, F; Shetty, AK; Sugahara, K; Sugiura, M; Yamada, S | 1 |
| Amster, IJ; Aslam, H; Laremore, TN; Linhardt, RJ; Wolff, JJ | 1 |
| Han, SY; Kim, DH; Lee, HS; Ryu, KY | 1 |
| Maccarana, M; Malmström, A; Pacheco, B | 1 |
| Ames, JB; Leary, JA; Meissen, JK; Schenauer, MR; Seo, Y | 1 |
| Bethea, HN; Li, K; Liu, J | 1 |
| Babin, V; Sagui, C | 1 |
| Feta, A; Kusche-Gullberg, M; Smeds, E | 1 |
| Li, JP | 1 |
| Kengen, SW; Raedts, J; van der Oost, J | 1 |
| Keire, DA; Sommers, CD | 1 |
| Huckerby, TN; Lauder, RM; Nieduszynski, IA; Sadler, IH | 1 |
| Helbert, W; Marfaing, H; Nyvall Collén, P; Rogniaux, H; Sassi, JF | 1 |
| Dulaney, SB; Huang, X; Liu, J; Sheng, J; Xu, Y | 1 |
| Higashi, K; Hosoyama, S; Matsumoto, A; Toida, T | 1 |
| Dejima, K; Hayashi, Y; Kinoshita-Toyoda, A; Nakato, E; Nakato, H; Peterson, J; Takemura, M; Toyoda, H | 1 |
| Alekseeva, A; Cassinelli, G; Casu, B; Guerrini, M; Naggi, A; Torri, G | 1 |
| Babu, P; Kuberan, B; Raman, K; Victor, XV | 1 |
| Leary, JA; Miller, RL; Schwörer, R; Turnbull, JE; Tyler, PC; Wei, W; Zubkova, OV | 1 |
| Fang, J; Li, JP; Lindahl, U; Song, T | 1 |
| Carnachan, SM; de Nys, R; Glasson, CRK; Hinkley, SFR; Kidgell, JT; Lopata, AL; Magnusson, M; Sims, IM; Taki, AC; Vamvounis, G | 1 |
| Dordick, JS; Ke, X; Linhardt, RJ; McCallum, SA; Paskaleva, E; Vaidyanathan, D; Vargason, T | 1 |
| Elli, S; Guerrini, M; Liu, J; Petitou, M; Stancanelli, E; Wang, Z | 1 |
| Alekseeva, A; Bisio, A; Gardini, C; Guerrini, M; Mazzini, G; Naggi, A | 1 |
| Chen, X; Ji, Y; Li, M; Li, P; Tian, Y; Zeng, H | 1 |
| Du, T; Kajimoto, T; Kaneko, K; Kobayashi, H; Matsushima, Y; Miura, T; Yoshitake, T | 1 |
1 review(s) available for glucuronic acid and iduronate
| Article | Year |
|---|---|
Glucuronyl C5-epimerase an enzyme converting glucuronic acid to iduronic acid in heparan sulfate/heparin biosynthesis.
Topics: Animals; Carbohydrate Epimerases; Glucuronic Acid; Heparin; Heparitin Sulfate; Iduronic Acid; Mice; Mice, Knockout | 2010 |
67 other study(ies) available for glucuronic acid and iduronate
| Article | Year |
|---|---|
Carbohydrate analysis of water-soluble uronic acid-containing polysaccharides with high-performance anion-exchange chromatography using methanolysis combined with TFA hydrolysis is superior to four other methods.
Topics: Animals; Anions; Carbohydrates; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Extracellular Space; Fungi; Glucuronates; Glucuronic Acid; Glycosaminoglycans; Hexuronic Acids; Hydrolysis; Iduronic Acid; Methanol; Pectins; Plants; Polysaccharides; Sensitivity and Specificity; Solubility; Trifluoroacetic Acid; Uronic Acids; Water | 1992 |
Analysis of glycosaminoglycan chains from different proteoglycan populations in human embryonic skin fibroblasts.
Topics: Cells, Cultured; Chemical Fractionation; Chondroitin Lyases; Chromatography; Dermatan Sulfate; Electrophoresis, Polyacrylamide Gel; Embryo, Mammalian; Fibroblasts; Glucuronates; Glucuronic Acid; Glycosaminoglycans; Heparin Lyase; Heparitin Sulfate; Humans; Iduronic Acid; Molecular Weight; Polysaccharide-Lyases; Proteoglycans; Sulfates | 1992 |
1H-N.m.r. spectral assignments for two series of heparin-derived oligosaccharides.
Topics: Carbohydrate Sequence; Disaccharides; Glucosamine; Glucuronates; Glucuronic Acid; Heparin; Iduronic Acid; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Oligosaccharides; Trisaccharides | 1992 |
Effects of sulfate deprivation on the production of chondroitin/dermatan sulfate by cultures of skin fibroblasts from normal and diabetic individuals.
Topics: Aggrecans; Cells, Cultured; Chondroitin Lyases; Chondroitin Sulfate Proteoglycans; Diabetes Mellitus; Extracellular Matrix Proteins; Female; Fibroblasts; Glucuronates; Glucuronic Acid; Glycoproteins; Humans; Iduronic Acid; Lectins, C-Type; Male; Proteoglycans; Tritium | 1991 |
Metal binding to heparin monosaccharides: D-glucosamine-6-sulphate, D-glucuronic acid, and L-iduronic acid.
Topics: Cadmium; Calcium; Glucosamine; Glucuronates; Glucuronic Acid; Heparin; Hymecromone; Iduronic Acid; Lead; Magnetic Resonance Spectroscopy; Metals; Molecular Conformation; Nickel; Zinc | 1991 |
Purification and characterization of iduronic acid-rich and glucuronic acid-rich proteoglycans implicated in human post-burn keloid scar.
Topics: Amino Acid Sequence; Amino Acids; Biopolymers; Burns; Disaccharides; Electrophoresis, Cellulose Acetate; Electrophoresis, Polyacrylamide Gel; Glucuronates; Glucuronic Acid; Glycosaminoglycans; Humans; Iduronic Acid; Keloid; Molecular Sequence Data; Proteoglycans | 1990 |
1H-n.m.r. investigation of naturally occurring and chemically oversulphated dermatan sulphates. Identification of minor monosaccharide residues.
Topics: Animals; Chondroitin; Dermatan Sulfate; Galactosamine; Glucuronates; Glucuronic Acid; Iduronic Acid; Magnetic Resonance Spectroscopy; Molecular Conformation; Swine; Uronic Acids | 1990 |
Determination of iduronic acid and glucuronic acid in glycosaminoglycans after stoichiometric reduction and depolymerization using high-performance liquid chromatography and ultraviolet detection.
Topics: Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Glucuronates; Glucuronic Acid; Glycosaminoglycans; Hydrolysis; Iduronic Acid; Oxidation-Reduction; Spectrophotometry, Ultraviolet; Uronic Acids | 1988 |
An investigation of the functional role of the carboxylic groups of heparin. Affinity for antithrombin III and anti-Xa activity of selectively carboxyl esterified heparin.
Topics: Antithrombin III; Chemical Phenomena; Chemistry; Esterification; Factor X; Factor Xa; Glucuronates; Glucuronic Acid; Heparin; Iduronic Acid; Structure-Activity Relationship; Sulfates; Uronic Acids | 1985 |
Urinary glycosaminoglycans bearing glucuronic acid or iduronic acid residue at the reducing terminals.
Topics: Carbohydrate Sequence; Chromatography; Chromatography, Gel; Glucuronates; Glucuronic Acid; Glycosaminoglycans; Humans; Iduronic Acid; Oxidation-Reduction | 1985 |
The uronic acid composition of anticoagulantly active and inactive heparin.
Topics: Animals; Blood Coagulation; Cattle; Glucuronates; Glucuronic Acid; Heparin; Iduronic Acid; Lung; Molecular Weight; Uronic Acids | 1985 |
Distribution of glucuronic and iduronic acid units in heparin chains.
Topics: Animals; Cattle; Chromatography, Affinity; Chromatography, Gel; Glucuronates; Glucuronic Acid; Heparin; Iduronic Acid; Mathematics; Molecular Weight; Nitrous Acid; Uronic Acids | 1985 |
Synthesis and secretion of sulphated glycosaminoglycans by bovine peridontal ligament fibroblast cultures.
Topics: Animals; Cattle; Cells, Cultured; Chondroitin Sulfates; Chromatography, DEAE-Cellulose; Dermatan Sulfate; Electrophoresis, Cellulose Acetate; Fibroblasts; Glucuronates; Glucuronic Acid; Glycosaminoglycans; Heparitin Sulfate; Iduronic Acid; Periodontal Ligament; Sulfates; Sulfur Radioisotopes | 1984 |
Improved analytical method for the hexuronic acids at the reducing terminals of glycosaminoglycans.
Topics: Chromatography, Paper; Glucuronates; Glucuronic Acid; Glycosaminoglycans; Hexuronic Acids; Humans; Hydrolysis; Iduronic Acid; Oxidation-Reduction; Uronic Acids | 1984 |
Specific association of iduronic acid-rich dermatan sulphate with the extracellular matrix of human skin fibroblasts cultured on collagen gels.
Topics: Biopolymers; Cells, Cultured; Child; Child, Preschool; Chondroitin; Chromatography, DEAE-Cellulose; Collagen; Culture Media; Dermatan Sulfate; Extracellular Matrix; Fibroblasts; Gels; Glucuronates; Glucuronic Acid; Glycosaminoglycans; Humans; Iduronic Acid; Male; Skin; Uronic Acids | 1983 |
Abnormal proteodermatan sulfate in three patients with Coffin-Lowry syndrome.
Topics: Abnormalities, Multiple; Adult; Bone and Bones; Cells, Cultured; Child, Preschool; Chondroitin; Dermatan Sulfate; Fibroblasts; Glucuronates; Glucuronic Acid; Humans; Iduronic Acid; Intellectual Disability; Male; Proteoglycans; Sex Factors; Skin; Skin Diseases; Syndrome | 1983 |
A simple and rapid electrophoretic method for the separation of glucuronic acid and iduronic acid.
Topics: Animals; Cartilage; Chondroitin; Chondroitin Sulfates; Electrophoresis, Cellulose Acetate; Glucuronates; Glucuronic Acid; Iduronic Acid; Indicators and Reagents; Sharks; Uronic Acids | 1981 |
Biosynthesis of dermatan sulphate. Loss of C-5 hydrogen during conversion of D-glucuronate to L-iduronate.
Topics: Carbon Radioisotopes; Cells, Cultured; Chondroitin; Chromatography, Ion Exchange; Dermatan Sulfate; Fibroblasts; Glucuronates; Glucuronic Acid; Humans; Iduronic Acid; Microsomes; Stereoisomerism; Tritium; Uronic Acids | 1981 |
A reversed phase HPLC method for the simultaneous determination of all monosaccharides contained in galactosaminoglycan isomers from human aorta proteoglycans.
Topics: Adult; Aorta; Chromatography, High Pressure Liquid; Galactosamine; Glucuronates; Glucuronic Acid; Glycosaminoglycans; Humans; Iduronic Acid; Isomerism; Middle Aged; Monosaccharides; Proteoglycans; Tunica Intima | 1994 |
Identification of glycosaminoglycans using high-performance liquid chromatography on a hydroxyapatite column.
Topics: Aminopyridines; Chondroitin Sulfates; Chromatography, High Pressure Liquid; Dermatan Sulfate; Disaccharides; Durapatite; Fluorescent Dyes; Glucuronates; Glucuronic Acid; Glycosaminoglycans; Heparitin Sulfate; Iduronic Acid; Molecular Weight | 1995 |
An animal cell mutant defective in heparan sulfate hexuronic acid 2-O-sulfation.
Topics: Animals; Carbohydrate Sequence; CHO Cells; Cricetinae; Disaccharides; Glucuronates; Glucuronic Acid; Heparitin Sulfate; Iduronic Acid; Molecular Sequence Data; Mutation; Sulfotransferases | 1996 |
NMR solution conformation of heparin-derived tetrasaccharide.
Topics: Carbohydrate Conformation; Carbohydrate Sequence; Glucosamine; Glucuronates; Glucuronic Acid; Heparin; Iduronic Acid; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Sequence Data; Molecular Structure; Oligosaccharides; Sulfates | 1996 |
Turnover of heparan sulfate depends on 2-O-sulfation of uronic acids.
Topics: Animals; Carbohydrate Sequence; CHO Cells; Cricetinae; Disaccharides; Glucuronates; Glucuronic Acid; Glucuronidase; Glycoside Hydrolases; Heparan Sulfate Proteoglycans; Heparitin Sulfate; Hexuronic Acids; Iduronic Acid; Molecular Sequence Data; Mutation; Oligosaccharides; Proteoglycans; Substrate Specificity; Sulfates | 1997 |
Calcium- and hydroxyapatite-binding properties of glucuronic acid-rich and iduronic acid-rich glycosaminoglycans and proteoglycans.
Topics: Adsorption; Animals; Binding Sites; Calcium; Chondroitin Sulfates; Collagen; Crystallization; Dentin; Dermatan Sulfate; Durapatite; Glucuronates; Glucuronic Acid; Glycosaminoglycans; Hydrogen-Ion Concentration; Iduronic Acid; In Vitro Techniques; Odontogenesis; Proteoglycans | 1998 |
Molecular cloning and characterization of a human uronyl 2-sulfotransferase that sulfates iduronyl and glucuronyl residues in dermatan/chondroitin sulfate.
Topics: Amino Acid Sequence; Animals; Baculoviridae; Base Sequence; Chondroitin Sulfates; Chromatography, High Pressure Liquid; Cloning, Molecular; Dermatan Sulfate; DNA, Complementary; Expressed Sequence Tags; Glucuronates; Glucuronic Acid; Humans; Iduronic Acid; Molecular Sequence Data; Spodoptera; Sulfotransferases; Tumor Cells, Cultured | 1999 |
Structural features and anticoagulant activities of a novel natural low molecular weight heparin from the shrimp Penaeus brasiliensis.
Topics: Animals; Antithrombins; Cattle; Chromatography, High Pressure Liquid; Chromatography, Paper; Electrophoresis, Agar Gel; Glucuronates; Glucuronic Acid; Heparin Lyase; Heparin, Low-Molecular-Weight; Iduronic Acid; Magnetic Resonance Spectroscopy; Molecular Weight; Penaeidae; Peptide Fragments; Polysaccharide-Lyases | 1999 |
A synthetic heparan sulfate pentasaccharide, exclusively containing L-iduronic acid, displays higher affinity for FGF-2 than its D-glucuronic acid-containing isomers.
Topics: Aorta; Binding Sites; Carbohydrate Sequence; Cell Division; Cells, Cultured; Fibroblast Growth Factor 2; Glucuronic Acid; Heparitin Sulfate; Humans; Iduronic Acid; Isomerism; Molecular Sequence Data; Muscle, Smooth, Vascular; Oligosaccharides | 1999 |
Human skin dermatan sulfate with sulfated and unsulfated non-reducing ends.
Topics: Acetylgalactosamine; Adult; Animals; beta-N-Acetylhexosaminidases; Dermatan Sulfate; Egg Proteins; Glucuronic Acid; Glucuronidase; Humans; Iduronic Acid; Iduronidase; Quail; Skin; Sulfatases; Sulfates | 1999 |
Biosynthesis of heparin/heparan sulphate: mechanism of epimerization of glucuronyl C-5.
Topics: Animals; Carbohydrate Epimerases; Cattle; Escherichia coli; Glucuronic Acid; Heparin; Heparitin Sulfate; Iduronic Acid; Kinetics; Liver; Polysaccharides, Bacterial | 2000 |
Enzymatic reconstruction of dermatan sulfate.
Topics: Animals; Carbohydrate Conformation; Carbohydrate Sequence; Cattle; Chromatography, High Pressure Liquid; Dermatan Sulfate; Glucuronic Acid; Glucuronidase; Glycosylation; Hyaluronoglucosaminidase; Iduronic Acid; Male; Mass Spectrometry; Molecular Sequence Data; Testis | 2000 |
Overexpression of different isoforms of glucosaminyl N-deacetylase/N-sulfotransferase results in distinct heparan sulfate N-sulfation patterns.
Topics: Acetylation; Amidohydrolases; Animals; Cell Line; Chromatography, Gel; Disaccharides; Glucuronic Acid; Heparitin Sulfate; Humans; Iduronic Acid; Isoenzymes; Mice; Molecular Weight; Polysaccharides; RNA, Messenger; Sulfates; Sulfotransferases; Transfection | 2000 |
Structural diversity of N-sulfated heparan sulfate domains: distinct modes of glucuronyl C5 epimerization, iduronic acid 2-O-sulfation, and glucosamine 6-O-sulfation.
Topics: Acetylglucosamine; Aged; Animals; Carbohydrate Conformation; Carbohydrate Epimerases; Cattle; Cell Line; Cells, Cultured; Disaccharides; Dogs; Glucosamine; Glucuronic Acid; Heparan Sulfate Proteoglycans; Hexuronic Acids; Humans; Iduronic Acid; Male; Mice; Structure-Activity Relationship; Sulfates | 2000 |
Determination and structural characterisation of dermatan sulfate in the presence of other galactosaminoglycans.
Topics: Animals; Cartilage; Chondroitin; Chromatography, Gel; Dermatan Sulfate; Glucuronic Acid; Iduronic Acid; Nasal Mucosa; Nose; Polysaccharides; Sheep | 2001 |
Identification of oligomeric domains within dermatan sulfate chains using differential enzymic treatments, derivatization with 2-aminoacridone and capillary electrophoresis.
Topics: Aminoacridines; Bacterial Proteins; Chondroitin ABC Lyase; Chondroitin Lyases; Chondroitinases and Chondroitin Lyases; Dermatan Sulfate; Disaccharides; Electrophoresis, Capillary; Female; Glucuronic Acid; Humans; Iduronic Acid; Leiomyoma; Myometrium; Oligosaccharides; Polysaccharides; Protein Structure, Tertiary; Substrate Specificity; Uterine Neoplasms | 2001 |
(1)H nuclear magnetic resonance spectroscopic analysis for determination of glucuronic and iduronic acids in dermatan sulfate, heparin, and heparan sulfate.
Topics: Animals; Chromatography, Gas; Chromatography, Gel; Chromatography, High Pressure Liquid; Dermatan Sulfate; Disaccharides; Epidermis; Glucuronic Acid; Heparin; Heparitin Sulfate; Iduronic Acid; Intestinal Mucosa; Magnetic Resonance Spectroscopy; Swine | 2001 |
Interaction of glucuronic acid and iduronic acid-rich glycosaminoglycans and their modified forms with hydroxyapatite.
Topics: Adsorption; Glucuronic Acid; Glycosaminoglycans; Hydroxyapatites; Iduronic Acid; Thermodynamics | 2002 |
Irreversible glucuronyl C5-epimerization in the biosynthesis of heparan sulfate.
Topics: Carbohydrate Epimerases; Carbohydrate Sequence; Carbohydrates; Cell Line; Chromatography, High Pressure Liquid; Galactose; Glucuronic Acid; Heparitin Sulfate; Humans; Iduronic Acid; Molecular Sequence Data; Nitrous Acid; Oligosaccharides; Polysaccharides; Substrate Specificity; Tritium | 2004 |
Synthesis of 2,5-anhydro-(beta-d-glucopyranosyluronate)- and (alpha-l-idopyranosyluronate)-d-mannitol hexa-O-sulfonate hepta sodium salt.
Topics: Carbohydrate Conformation; Disaccharides; Glucuronic Acid; Hexoses; Iduronic Acid; Molecular Structure; Salts; Sodium Acetate; Sodium Hydroxide; Sulfuric Acid Esters; Thioglycosides | 2004 |
Heparan sulfate synthesized by mouse embryonic stem cells deficient in NDST1 and NDST2 is 6-O-sulfated but contains no N-sulfate groups.
Topics: Amidohydrolases; Animals; Blastocyst; Carbohydrate Epimerases; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; DNA, Complementary; Embryo, Mammalian; Gene Expression Regulation, Developmental; Genotype; Glucosamine; Glucuronic Acid; Glycosaminoglycans; Heparitin Sulfate; Iduronic Acid; Mice; Mice, Transgenic; Nitrous Acid; Polysaccharides; Reverse Transcriptase Polymerase Chain Reaction; Stem Cells; Sulfates; Sulfotransferases; Sulfur | 2004 |
Structural and functional characterization of oversulfated chondroitin sulfate/dermatan sulfate hybrid chains from the notochord of hagfish. Neuritogenic and binding activities for growth factors and neurotrophic factors.
Topics: Animals; Binding, Competitive; Brain; Cell Line; Chondroitin Sulfates; Chondroitinases and Chondroitin Lyases; Chromatography, Gel; Dermatan Sulfate; Disaccharides; Epidermal Growth Factor; Glucuronic Acid; Growth Substances; Hagfishes; Heparin; Hippocampus; Humans; Iduronic Acid; Insecta; Kinetics; Nerve Growth Factors; Notochord; Protein Binding; Rats; Recombinant Proteins; Time Factors | 2004 |
Heparan sulfate C5-epimerase is essential for heparin biosynthesis in mast cells.
Topics: Animals; Carbohydrate Epimerases; Carbohydrate Sequence; Glucuronic Acid; Heparan Sulfate Proteoglycans; Heparin; Heparitin Sulfate; Humans; Iduronic Acid; Mast Cells; Mice; Models, Biological; Models, Genetic; Molecular Sequence Data; Polysaccharides; Time Factors | 2006 |
Distinguishing glucuronic from iduronic acid in glycosaminoglycan tetrasaccharides by using electron detachment dissociation.
Topics: Carbohydrate Sequence; Cyclotrons; Electrons; Glucuronic Acid; Glycosaminoglycans; Heparitin Sulfate; Iduronic Acid; Mass Spectrometry; Molecular Sequence Data; Oligosaccharides | 2007 |
Determination of iduronic acid and glucuronic acid in sulfated chondroitin/dermatan hybrid chains by (1)H-nuclear magnetic resonance spectroscopy.
Topics: Animals; Chondroitin Sulfates; Dermatan Sulfate; Disaccharides; Glucuronic Acid; Iduronic Acid; Magnetic Resonance Spectroscopy | 2008 |
Electron-induced dissociation of glycosaminoglycan tetrasaccharides.
Topics: Electrons; Fourier Analysis; Glucuronic Acid; Glycosaminoglycans; Heparitin Sulfate; Hexuronic Acids; Iduronic Acid; Ions; Isomerism; Molecular Structure; Oligosaccharides; Tandem Mass Spectrometry | 2008 |
The degradation of glycosaminoglycans by intestinal microflora deteriorates colitis in mice.
Topics: Animals; Anti-Bacterial Agents; Chondroitin Sulfates; Colitis; Galactosamine; Glucosamine; Glucuronic Acid; Glycosaminoglycans; Hyaluronic Acid; Iduronic Acid; Intestinal Mucosa; Male; Mice; Mice, Inbred ICR; Uronic Acids | 2009 |
Two dermatan sulfate epimerases form iduronic acid domains in dermatan sulfate.
Topics: Amino Acid Sequence; Cell Line; Cells, Cultured; Dermatan Sulfate; Fibroblasts; Glucuronic Acid; Golgi Apparatus; Humans; Iduronic Acid; Molecular Sequence Data; Plasmids; Protein Structure, Tertiary; Racemases and Epimerases; RNA, Small Interfering; Sulfotransferases | 2009 |
Heparan sulfate separation, sequencing, and isomeric differentiation: ion mobility spectrometry reveals specific iduronic and glucuronic acid-containing hexasaccharides.
Topics: Carbohydrate Sequence; Glucuronic Acid; Heparitin Sulfate; Iduronic Acid; Isomerism; Magnetic Resonance Spectroscopy; Oligosaccharides; Spectrometry, Mass, Electrospray Ionization | 2009 |
Using engineered 2-O-sulfotransferase to determine the activity of heparan sulfate C5-epimerase and its mutants.
Topics: Carbohydrate Epimerases; Catalysis; Catalytic Domain; Disaccharides; Dose-Response Relationship, Drug; Glucuronic Acid; Humans; Iduronic Acid; Models, Chemical; Mutagenesis; Mutation; Polysaccharides; Protein Engineering; Sulfotransferases; Tyrosine | 2010 |
Conformational free energies of methyl-alpha-L-iduronic and methyl-beta-D-glucuronic acids in water.
Topics: Algorithms; Carbohydrate Sequence; Computer Simulation; Glucuronic Acid; Iduronic Acid; Molecular Conformation; Molecular Sequence Data; Thermodynamics; Water | 2010 |
Target selection of heparan sulfate hexuronic acid 2-O-sulfotransferase.
Topics: Animals; Blotting, Western; Cells, Cultured; Glucuronic Acid; Heparitin Sulfate; Humans; Iduronic Acid; Kidney; Mice; Polysaccharides; Substrate Specificity; Sulfotransferases | 2010 |
Occurrence of L-iduronic acid and putative D-glucuronyl C5-epimerases in prokaryotes.
Topics: Amino Acid Sequence; Archaea; Bacteria; Carbohydrate Epimerases; Glucuronic Acid; Glycosaminoglycans; Heparin; Iduronic Acid; Molecular Sequence Data; Phylogeny; Sequence Alignment | 2011 |
Detection of possible economically motivated adulterants in heparin sodium and low molecular weight heparins with a colorimetric microplate based assay.
Topics: Chondroitin Sulfates; Colorimetry; Glucuronic Acid; Glycosaminoglycans; Heparin; Heparin Lyase; Heparin, Low-Molecular-Weight; Iduronic Acid; Polymers; Thiophenes | 2011 |
Characterisation of oligosaccharides from the chondroitin/dermatan sulphates: (1)H and (13)C NMR studies of oligosaccharides generated by nitrous acid depolymerisation.
Topics: Carbohydrate Sequence; Chondroitin; Dermatan Sulfate; Glucuronic Acid; Iduronic Acid; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Nitrous Acid; Oligosaccharides; Polymerization | 2011 |
Ulvan lyases isolated from the Flavobacteria Persicivirga ulvanivorans are the first members of a new polysaccharide lyase family.
Topics: Amino Acid Sequence; Carbohydrate Conformation; Carbohydrate Sequence; Cell Wall; Chlorophyta; Chromatography, High Pressure Liquid; Chromatography, Liquid; Cloning, Molecular; Enzymes; Glucuronic Acid; Iduronic Acid; Kinetics; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Peptides; Polysaccharide-Lyases; Tandem Mass Spectrometry; Ulva | 2011 |
Uncovering biphasic catalytic mode of C5-epimerase in heparan sulfate biosynthesis.
Topics: Carbohydrate Epimerases; Catalysis; Glucuronic Acid; Heparitin Sulfate; Humans; Iduronic Acid; Recombinant Proteins | 2012 |
Simultaneous determination of uronates found in polysaccharides from natural products by HPLC with fluorometric detection.
Topics: Alginates; Chromatography, High Pressure Liquid; Dermatan Sulfate; Fluorometry; Glucuronic Acid; Hexuronic Acids; Iduronic Acid; Polysaccharides; Temperature; Trifluoroacetic Acid; Uronic Acids | 2012 |
Analysis of Drosophila glucuronyl C5-epimerase: implications for developmental roles of heparan sulfate sulfation compensation and 2-O-sulfated glucuronic acid.
Topics: Animals; Carbohydrate Epimerases; Drosophila; Drosophila Proteins; Fibroblast Growth Factors; Gene Expression Regulation, Developmental; Glucuronates; Glucuronic Acid; Heparitin Sulfate; Iduronic Acid; Longevity; Mutagenesis, Site-Directed; Mutation; Signal Transduction; Sulfotransferases | 2013 |
Structural features of glycol-split low-molecular-weight heparins and their heparin lyase generated fragments.
Topics: Borohydrides; Chromatography, Reverse-Phase; Dalteparin; Enoxaparin; Glucuronic Acid; Heparin Lyase; Heparin, Low-Molecular-Weight; Hydrolysis; Iduronic Acid; Magnetic Resonance Spectroscopy; Oxidation-Reduction; Periodic Acid; Tinzaparin | 2014 |
A rapid, nonradioactive assay for measuring heparan sulfate C-5 epimerase activity using hydrogen/deuterium exchange-mass spectrometry.
Topics: Animals; Biocatalysis; Carbohydrate Epimerases; Chromatography, Ion Exchange; Chromatography, Liquid; Deuterium Exchange Measurement; Disaccharides; Enzyme Assays; Glucuronic Acid; Heparitin Sulfate; Humans; Iduronic Acid; Mass Spectrometry; Sf9 Cells | 2015 |
Composition, sequencing and ion mobility mass spectrometry of heparan sulfate-like octasaccharide isomers differing in glucuronic and iduronic acid content.
Topics: Binding Sites; Glucuronic Acid; Heparitin Sulfate; Iduronic Acid; Isomerism; Polysaccharides; Sequence Analysis; Spectrometry, Mass, Electrospray Ionization | 2015 |
Enzyme overexpression - an exercise toward understanding regulation of heparan sulfate biosynthesis.
Topics: Binding Sites; Carbohydrate Epimerases; Catalysis; Glucuronic Acid; HEK293 Cells; Heparitin Sulfate; Humans; Iduronic Acid; Mutation; Protein Binding; Sulfotransferases | 2016 |
The molecular weight of ulvan affects the in vitro inflammatory response of a murine macrophage.
Topics: Animals; Cell Survival; Glucuronic Acid; Iduronic Acid; Immunologic Factors; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Macrophages; Mice; Molecular Weight; Peptide Fragments; Polysaccharides; RAW 264.7 Cells; Rhamnose; Seaweed; Ulva; Xylose | 2020 |
Elucidating the unusual reaction kinetics of D-glucuronyl C5-epimerase.
Topics: Biocatalysis; Carbohydrate Conformation; Carbohydrate Epimerases; Glucuronic Acid; Humans; Iduronic Acid; Kinetics | 2020 |
Degeneracy of the Antithrombin Binding Sequence in Heparin: 2-O-Sulfated Iduronic Acid Can Replace the Critical Glucuronic Acid.
Topics: Anticoagulants; Antithrombins; Glucuronic Acid; Heparin; Iduronic Acid; Magnetic Resonance Spectroscopy; Molecular Conformation; Oligosaccharides; Polysaccharides; Sulfates | 2020 |
Saturated tetrasaccharide profile of enoxaparin. An additional piece to the heparin biosynthesis puzzle.
Topics: Chromatography, High Pressure Liquid; Enoxaparin; Fibrinolytic Agents; Glucosamine; Glucuronic Acid; Heparin; Heparin Lyase; Humans; Iduronic Acid; Magnetic Resonance Spectroscopy; Mass Spectrometry; Oligosaccharides | 2021 |
Precolumn derivatization LC-MS/MS method to simultaneous quantitation of 10 monosaccharides in rat plasma.
Topics: Acetylgalactosamine; Acetylglucosamine; Animals; Chromatography, High Pressure Liquid; Chromatography, Liquid; Fucose; Galactose; Glucose; Glucuronic Acid; Iduronic Acid; Mannose; Monosaccharides; Rats; Rats, Sprague-Dawley; Rhamnose; Tandem Mass Spectrometry; Xylose | 2023 |
Facile Preparation of L-Iduronic Acid and α-L-Iduronidation Using Methyl 1,2,3,4-Tetra-O-acetyl-α-L-iduronate as Glycosyl Donor.
Topics: Glucuronates; Glucuronic Acid; Iduronic Acid; Imides; Isomerism | 2023 |