Page last updated: 2024-08-24

glucose, (beta-d)-isomer and stilbenes

glucose, (beta-d)-isomer has been researched along with stilbenes in 745 studies

Research

Studies (745)

TimeframeStudies, this research(%)All Research%
pre-19905 (0.67)18.7374
1990's19 (2.55)18.2507
2000's142 (19.06)29.6817
2010's434 (58.26)24.3611
2020's145 (19.46)2.80

Authors

AuthorsStudies
Baba, K; Hata, K; Kozawa, M1
Huang, QB1
Liu, C; Zhang, Q; Zhou, Q1
He, HD; Shan, CW; Shao, SL; Yang, SQ; Zhang, PW1
Luo, SF; Yu, CL; Zhang, PW1
Eaton, JW; Greenberg, CS; Skubitz, KM; Vercellotti, GM1
Shan, CW1
Goetzl, EJ; Tauber, AI1
Chen, BZ; Guo, HZ; Hy, LY; Luo, SR; Wang, LW; Xiao, PG1
Hase, K; Iida, K; Kadota, S; Namba, T; Shimomura, K; Sudo, S1
Luo, SF; Wang, YZ; Yu, CL; Zhang, PW1
Li, RS; Luo, SF; Sun, LS; Wang, YZ; Yu, CL; Zhang, PW1
Duck, CC; Grech, JN; Li, Q; Roufogalis, BD1
Jin, CH; Jin, LJ; Mo, GY1
Basnet, P; Kadota, S; Namba, T; Terashima, S1
Chansouria, JP; Jahromi, MA; Manickam, M; Ramanathan, M; Ray, AB1
Bellini, B; Miglierini, G; Orsini, F; Pelizzoni, F1
Aburjai, T; Orsini, F; Pelizzoni, F; Rogers, CB; Verotta, L1
Okuda, T; Sato, M; Suzuki, Y; Yokotsuka, K1
Cichewicz, RH; Kouzi, SA1
Chang, IM; Jang, DS; Kang, BS; Kim, Y; Min, KR; Ryu, SY1
Cabanis, JC; Carando, S; Deffieux, G; Mérillon, JM; Teissedre, PL; Waffo-Téguo, P1
de La Torre-Boronat, MC; Ibern-Gómez, M; Lamuela-Raventós, RM; Romero-Pérez, AI1
Chen, Y; Ho, CT; Rosen, RT; Vastano, BC; Zhou, Z; Zhu, N1
Harima, S; Kageura, T; Matsuda, H; Morikawa, T; Toguchida, I; Yoshikawa, M1
Chen, SA; Li, HF; Wu, SN1
Hipskind, JD; Paiva, NL1
Iinuma, M; Ito, T; Nakaya, K; Riswan, S; Tanaka, T1
Bae, EA; Han, MJ; Kim, DH; Park, EK1
Cuendet, M; Hostettmann, K; Potterat, O; Salvi, A; Testa, B1
Baderschneider, B; Winterhalter, P1
Cantos, E; de Pascual-Teresa, S; García-Viguera, C; Tomás-Barberán, FA1
Kimura, Y; Okuda, H1
Andrés-Lacueva, C; de La Torre-Boronat, MC; Lamuela-Raventós, RM; Romero-Pérez, AI1
Cuendet, M; Kinghorn, AD; Lee, D; Mérillon, J; Pezzuto, JM; Waffo-Teguo, P1
Harima, S; Matsuda, H; Morikawa, T; Park, JY; Toguchida, I; Yoshikawa, M1
Chen, L; Han, Y; Yang, F; Zhang, T1
de la Torre-Boronat, MC; Ibern-Gómez, M; Lamuela-Raventós, RM; Roig-Pérez, S1
Bharadwaj, D; Du Clos, TW; Markham, E; Mold, C1
Guo, D; Huang, D; Min, D; Wang, H; Xu, L; Zhang, Z; Zheng, J1
Chun, YJ; Kim, HB; Kim, MY; Lee, SH; Ryu, SY1
Decendit, A; Deffieux, G; Krisa, S; Mérillon, JM; Monti, JP; Richard, T; Vercauteren, J; Waffo-Teguo, P1
Achmad, SA; Aimi, N; Aminah, NS; Ghisalberti, EL; Hakim, EH; Kitajima, M; Syah, YM; Takayama, H1
Choi, BW; Ju, JH; Lee, BH; Park, YJ; Ryu, G; Ryu, SY1
Brandolini, V; Durini, E; Maietti, A; Manfredini, S; Tedeschi, P; Vertuani, S1
Xue, L1
Huang, HX; Jin, CH; Zhao, Q2
Huang, L; Wang, L; Wang, ZT; Zhang, M1
Kimura, Y1
Bonello, P; Gordon, TR; McNee, WR; Storer, AJ; Wood, DL1
Ainis, T; Bottari, C; Cavallaro, A; Fimiani, V1
Huang, Q; Huang, X; Jin, C; Kan, W; Liu, J; Yan, WS; Zhao, KS1
Chiou, WF; Chou, CJ; Lin, LC1
Sun, YK; Zhang, XQ; Zhao, HP1
Lu, XH; Sun, JH; Wang, CY; Yuan, ZF; Zhang, LT1
Dugo, G; Dugo, P; La Torre, GL; Mondello, L; Salvo, F1
Ashurmetov, O; Fukuzawa, K; Higuti, T; Honda, G; Ito, M; Kodzhimatov, OK; Kogure, K; Okasaka, M; Shibata, H; Takaishi, Y1
Ling, ZY; Lu, ZY; Shu, SY; Wang, XY1
Lizama, V; Mallavia, R; Micol, V; Moreno-Labanda, JF; Pérez-Fons, L; Saura, D1
Balestrazzi, A; Bollini, R; Calligari, P; Confalonieri, M; Giorcelli, A; Mattivi, F; Sparvoli, F; Tava, A; Vrhovsek, U1
Chen, WS; Li, TJ; Liu, HJ; Qiu, Y; Rui, YC; Zhang, L1
Schreiber, L; Schulze, K; Szankowski, I1
Kim, YC; Sung, SH; Yang, H1
Decendit, A; Ennamany, R; Henry, C; Krisa, S; Mérillon, JM; Vitrac, X1
Bai, HB; Long, J; Wang, JF1
Li, SL; Liu, ZL; Song, ZQ; Zhang, L1
Chen, M; Dai, Y; Feng, L; He, J; Shu, Y1
Kim, YC; Lee, MK; Yang, H1
Callemien, D; Collin, S; Jerkovic, V1
Andres-Lacueva, C; Covas, MI; Jaeger, W; Jáuregui, O; Lamuela-Raventós, RM; Miksits, M; Urpí-Sardà, M1
Bornet, A; Delaunay, JC; Mérillon, JM; Richard, T; Teissédre, PL; Valls, J; Vanderlinde, R; Vitrac, X1
Biondi, DM; Rocco, C; Ruberto, G1
Coulomb, PO; Gallet, S; Lacombe, JM; Tomao, V; Vian, MA1
Cui, HH; Kang, YH; Li, RM; Wang, ZQ; Wang, ZY1
Baumert, A; Becker, HC; Hüsken, A; Milkowski, C; Möllers, C; Strack, D1
Jin, W; Tu, PF1
Jiang, FX; Li, XX; Liu, EB; Ren, RF; Wei, HQ; Zhao, XL1
Decendit, A; Delaunay, JC; Krisa, S; Larronde, F; Mérillon, JM; Monti, JP; Richard, T1
Avar, P; Mark, L; Nikfardjam, MS; Ohmacht, R1
Merillon, JM; Monti, JP; Richard, T; Vitrac, X1
Almofti, MR; Chen, WS; Kang, H; Li, TJ; Lu, L; Rui, YC; Sun, LN; Yang, PY; Zhang, J1
Chu, X; Liu, R; Sun, A1
Wang, DQ; Wang, W1
Fan, G; Gao, S; Hong, Z; Wu, Y; Yang, S; Yin, X1
Bilkis, I; Flaishman, MA; Kerem, Z; Sivan, L1
Ali, Z; Darnaedi, D; Furusawa, M; Iinuma, M; Iliya, I; Ito, T; Murata, J; Nakaya, K; Tanaka, T1
Abrman, P; Prokop, J; Seligson, AL; Sovak, M1
Liu, Q; Tang, L; Wang, J; Xu, J; Ye, S1
Chu, IK; Lam, CN; Lo, C; Schmidt, J; Springob, K; Yu, CK1
Briviba, K; Fritsche, S; Rühmann, S; Szankowski, I; Treutter, D1
Yu, SH; Zha, JP; Zhan, WH; Zhang, DQ1
Cheng, Y; Guo, S; Ouyang, S; Sun, L; Xu, J; Zhang, HT; Zhang, Y1
Jing, X; Liu, W; Liu, Y; Lv, C; Wang, C; Wang, Q; Zhang, L1
Cui, H; Kang, Y; Li, R; Wang, Z1
Ai, HX; Li, L; Wei, HF; Xing, Y; Ye, CF; Zhang, L1
Wu, B; Zhang, HJ1
Desmoulière, A; Girard, D; Henry-Vitrac, C; Krisa, S; Mérillon, JM1
Che, CT; Cheng, CH; Lau, CB; Leung, PS; Li, JM1
Ma, YT; Song, LK; Wan, DG1
Cai, SQ; Komatsu, K; Ling, Y; Meselhy, MR; Nagayama, Y; Omote, T; Tanaka, K1
Chang, HW; Jahng, Y; Jeong, BS; Lee, CS; Lee, ES; Lee, SH; Lee, YK; Moon, DC; Son, JK; Woo, MH; Xu, ML; Zheng, MS1
Furasawa, M; Iinuma, M; Iliya, I; Ito, T; Murata, H; Nakaya, K; Oyama, M; Tanaka, T1
De Luca, V; Hall, D1
Lü, TS; Yao, QQ; Zhang, ZG1
Dong, YS; Guo, YX; Liu, L; Wang, H; Xiu, ZL; Zhang, DJ1
Fu, LC; Gao, X; Hu, YJ1
Chen, X; Zhong, D; Zhou, M1
Au, A; Birt, DF; Brummer, EC; Kaiser, MS; Kineman, BD; Paiva, NL1
Chen, X; Han, D; He, H; Jing, J; Li, T; Ma, L; Ren, W; Wang, G; Wang, R; Wu, X; Yu, Q; Zhao, Y; Zheng, Y1
Choi, JW; Ha, J; Kim, HJ; Lee, KT; Lee, KW; Lee, YS; Park, HJ1
Barrera-García, VD; Chassagne, D; De Aguirre, C; Di Majo, D; Gougeon, RD; Voilley, A1
Ding, Y; Liu, D; Tang, HF; Yang, CE; Zhang, SQ1
Chen, XY; Zhong, DF; Zhou, MJ1
Collin, S; Jerkovic, V2
Fang, L; Feng, B; Li, L; Tang, Y; Wang, R; Ye, C; Zhang, L1
Chen, S; Han, T; Wang, J; Wang, X; Zhao, L1
Chu, IK; Lo, C; Shih, CH; Yu, CK1
Li, F; Wang, CH; Zhang, W; Zhu, WZ1
Chen, QY; Chen, YH; Dong, WR; Hu, GD; Qiu, XX; Xiao, YQ; Zhao, BL; Zou, ZZ1
Gershenzon, J; Li, SH; Niu, XM; Schneider, B; Weston, J; Zahn, S1
Huang, ZJ; Miao, XY; Shen, YZ; Yu, SH1
Airado-Rodríguez, D; Durán-Merás, I; Galeano-Díaz, T1
Leung, KS; Leung, SY; Lu, G; Qian, G1
Amiano, P; Andres-Lacueva, C; Ardanaz, E; Barricarte, A; Berenguer, T; Chirlaque, MD; Dorronsoro, M; González, CA; Jakszyn, P; Lamuela-Raventós, RM; Larrañaga, N; Martínez, C; Navarro, C; Quirós, JR; Sánchez, MJ; Tormo, MJ; Zamora-Ros, R1
Kang, YH; Li, RM; Ma, WW; Wang, ZQ; Wang, ZY1
Guan, S; Li, P; Su, W; Wang, N; Wang, Y1
Fabris, S; Momo, F; Ravagnan, G; Stevanato, R1
Jiao, XW; Yan, P; Zhang, XN; Zhao, SJ; Zhao, X1
Cui, F; Wang, YP; Yang, CY; Zhang, LP; Zhang, Y1
Johnson, CE; Leblanc, MR; Wilson, PW1
Li, GK; Wang, JX; Xiao, XH1
Afonso, JM; Andrade, PB; Dopico-García, MS; Fique, A; Guerra, L; Pereira, O; Seabra, RM; Valentão, P1
Li, F; Shen, Y; Wang, CH; Wang, YQ; Zhang, W2
Adam, M; Benová, B; Krajícek, M; Královský, J; Onderková, K1
Du, J; Jia, M; Qin, LP; Wu, JZ; Xing, WW; Zhang, H1
Dong, Y; Wang, H; Xiu, ZL1
Apgar, J; Davey, MH; Glinski, JA; Hurst, WJ; Miller, KB; Stuart, DA1
Fu, MH; Tu, YY; Yang, L; Zhang, D1
Du, D; Hu, Y; Li, J; Liu, J; Ma, S; Qu, J; Yu, S1
Bi, K; Huang, Q; Jia, Y; Li, Q; Zhang, W; Zhu, M1
Cullin, C; Delaunay, JC; Immel, F; Monti, JP; Rivière, C1
Du, J; Huang, BK; Jia, M; Qin, LP; Sun, LN; Wu, JZ; Xing, WW; Zhang, H1
Condori, J; Cramer, C; Medina-Bolivar, F; Medrano, G; Nair, V; Sivakumar, G1
Pei, YH; Yang, HL; Yu, SS1
Dang, Z; Liu, B; Pu, YT; Wen, Z; You, XK; Zheng, ZK1
Chen, JG; Dong, LD; Gu, J; Wang, F; Wang, T; Wu, PF; Wu, WN; Xiong, Z; Yang, YJ1
Wang, CH; Wang, YQ; Xu, XL; Zhang, W; Zhu, WZ1
Ahmed, N; Choudhary, MI; Gaffney, J; Hussain, S; Naz, H; Slevin, M; West, D1
Hu, Y; Huan, M; Mei, Q; Teng, Z; Yang, R; Yang, Z; Zhang, B; Zhang, X; Zhou, S1
He, G; Jiang, Z; Long, M; Tu, Z; Xu, J; Yang, G1
Cluzet, S; Faurie, B; Mérillon, JM1
Fan, P; Hay, AE; Hostettmann, K; Marston, A1
Potrebko, I; Resurreccion, AV1
Gu, J; Liu, W; Wang, C; Wang, Q; Yuan, Z; Zhang, L1
Bu, HM; Li, Q; Ma, HJ; Qi, Z; Wang, ML; Zhang, LP; Zhang, Y1
Cai, Z; Ma, AD; Yang, XM; Yu, F1
Bucheli, P; Lu, YH; Song, W; Wang, HJ; Wei, DZ; Zhang, PF1
Biasutto, L; Bradaschia, A; Fallica, M; Garbisa, S; Marotta, E; Mattarei, A; Paradisi, C; Zoratti, M1
Wang, JL; Wang, WQ; Zhang, SH1
Fu, XF; Luo, HB; Shi, XQ; Yang, JS; Yang, QD1
Chen, S; Dong, J; Hashi, Y; Wan, L; Wang, H1
Jensen, JS; O'Neill, VA; Wertz, CF1
Qin, W; Sheng, C; Wang, CH; Yu, YH; Zhao, KS1
Broer, I; Frolov, A; Kopertekh, L; Schiemann, J; Schulze, K; Strack, D1
Andoh, K; Kamiyama, M; Kishimoto, Y; Kondo, K; Tani, M; Utsunomiya, K1
Ho, CT; Huang, D; Lv, L; Sang, S; Shao, X; Wang, L1
Barbieri, F; Indraccolo, U1
Akao, Y; Aoyama, C; Awang, K; Hadi, AH; Hirasawa, Y; Morita, H; Sato, S; Shimokawa, Y; Shiro, M; Takeo, J1
Mikulski, D; Molski, M1
Caro, I; Palacios, V; Pérez, L; Roldán, A1
Birt, DF; Brummer, EC; Kineman, BD; Paiva, NL1
Chang, KW; Jeon, JG; Kim, JE; Kwon, YR; Pandit, S; Son, KJ1
Yang, J; Yang, Q; Zeng, J; Zheng, L; Zhou, Z1
Lin, HB; Xu, B; Xu, JP; Zhou, H1
Min, B; Ryoo, S; Woo, A1
Chen, CX; Gao, JP; Gu, WL; Lü, J; Wang, Y; Wu, Q1
Chen, J; Kang, X; Li, X; Li, Y; Sun, J; Sun, X1
Cai, L; Qu, X; Zhang, Q; Zhong, G1
Alex, D; Deng, YH; Huang, HQ; Lee, SM; Leung, GP; Wang, N; Wang, YT; Yu, N1
Cai, F; Jia, Y; Li, C; Li, J; Liu, Q; Tang, J; Wang, C; Yang, Y; Zhao, X1
Alcántara, D; Beltrán, D; Espín, JC; García-Conesa, MT; Larrosa, M; Lucas, R; Morales, JC; Selma, MV; Tomás-Barberán, F; Tomé-Carneiro, J; Urbán, C; Yáñez-Gascón, MJ1
Airado-Rodríguez, D; Durán-Merás, I; Galeano-Díaz, T; Godoy-Caballero, Mdel P1
Abe, N; Chelladurai, V; Iinuma, M; Ito, T; Masuda, Y; Oyama, M; Sawa, R; Takahashi, Y1
Chang, YH; Jeong, ET; Jin, MH; Kim, MS; Park, SG1
Chen, HB; Liang, ZT; Shi, YX; Zhao, ZZ1
Chen, JG; Fu, H; Hu, ZL; Long, LH; Wang, F; Wang, T; Wang, W; Wu, PF; Xie, N; Yang, YJ1
Fernández-de Córdova, ML; Molina-García, L; Ruiz-Medina, A1
Feng, JL; Jia, CH; Li, YX; Liu, L; Wang, JY; Wang, LS; Wei, XX; Xun, AY; Yao, J; Zeng, WS; Zhao, L1
Ju, J; Qiu, W; Wang, D; Wang, X; Zhang, Z1
Shao, LJ; Wang, JN1
Yang, J; Yang, QD; Zeng, J; Zheng, LJ; Zhou, ZW1
Ha, ML; Wang, FY; Wang, WT; Wang, Y; Xu, ZJ; Zhang, XL1
Jin, XF; Wang, WT; Xu, YX; Xu, ZJ; Zhang, XL1
Li, F; Shen, Y; Wang, CH; Xu, XL; Zhang, W1
Ambrozova, G; Drabikova, K; Harmatha, J; Jancinova, V; Lojek, A; Nosal, R; Perecko, T; Rackova, L; Smidrkal, J1
Andrés-Lacueva, C; Chiva-Blanch, G; Estruch, R; Lamuela-Raventós, RM; Llorach, R; Rotchés-Ribalta, M; Urpi-Sarda, M; Zamora-Ros, R1
Chen, J; Kang, X; Li, G; Li, X; Li, Y; Qin, R; Sun, J; Tao, L1
Ambassa, P; Kamga, J; Kuete, V; Ngadjui, BT; Ngameni, B; Poumale, HM; Sandjo, LP1
Ou-Yang, HZ; Qi, AD; Ren, XL; Wang, GF; Wang, M1
Abe, N; Chelladurai, V; Iinuma, M; Ito, T; Oyama, M; Sawa, R; Takahashi, Y1
Cheng, M; Song, SL; Wei, Y; Zhang, LP; Zhang, Y1
Chen, XF; Huang, YJ; Wang, YQ; Xu, XL; Zhang, W1
Choi, DK; Koppula, S; Suk, K1
Bie, X; Liu, H; Liu, M; Wan, H; Yang, J; Zhang, G; Zhang, Y1
Cottarelli, A; Fuggetta, MP; Guida, S; Lanzilli, G; Nicotera, G; Ravagnan, G1
Córdova, ML; Molina-García, L; Ruiz-Medina, A1
Fuggetta, M; Mattivi, F1
He, S; Liao, G; Zhang, Z1
Li, L; Sun, FL; Zhang, L; Zhang, RY1
Huang, X; Mazza, G1
Castaldi, MA; Cobellis, L; Colacurci, N; De Franciscis, P; Giordano, V; Torella, M; Trabucco, E1
Kai, G; Liu, J; Wang, F; Wang, L; Xiao, J; Yu, X1
Chen, S; Gu, H; Lou, Z; Lv, G; Shan, L2
Liu, Z; Shao, L; Sheng, S; Zhao, S; Zhao, W; Zhuang, C1
Bian, H; Huang, F; Liang, H; Ni, S; Pan, Y; Peng, X; Yao, D; Yu, Q1
Keppel Hesselink, JM1
Jie, C; Lijia, W; Lin, B; Mao, Y; Shiyu, S; Tianbao, Z; Tingyu, L; Zhiyu, L1
Miao, Q; Miao, S; Wang, J; Wang, S; Xie, Y; Yang, Q1
Mao, F; Xiao, J; Yamamoto, K; Yang, F; Zhang, C; Zhao, Y1
Fan, J; Liao, J; Liu, H; Peng, H; Wu, J; Zhang, Y; Zhao, S1
Li, N; Mao, XJ; Wang, J; Wang, MJ; Xie, J; Yu, J; Zhao, RH; Zhaori, GT1
Chen, L; Hou, FJ; Li, S; Xu, CY; Zhng, RL1
Bohlmann, J; Fenning, TM; Gershenzon, J; Hammerbacher, A; Ralph, SG; Schmidt, A1
Eguchi, R; Ikeda, K; Kaji, K; Kato, E; Kunimasa, K; Mori, H; Mori, M; Ohta, T; Tani, H; Tatefuji, T; Yamori, Y1
Hwang, D; Kim, JK; Lim, YH; Park, KT; Yoo, Y1
Chen, J; Chen, WH; Shi, YP1
Chang, MJ; Wang, JL; Xiao, JH; Zeng, C1
Chen, J; Jiang, L; Li, X; Sun, X; Tao, L; Tian, J; Zhang, L; Zhang, X1
Du, Y; Ji, H; Li, L; Li, S; Liu, H; Zhang, X1
Du, X; Hou, Y; Li, M; Li, Z; Yang, Q; Yuan, M; Zhou, L; Zhou, Z1
Cai, Y; Chen, J; Chong, Y; Yan, A; Yang, X1
Chen, X; Fang, D; Huang, Q; Li, G; Wu, X; Zhang, G1
Chen, XF; Huang, YJ; Lin, DY; Xu, XL; Zhang, W1
Bian, HN; Brunk, UT; Song, R; Wang, X; Zhao, KS; Zhao, M1
Brackman, G; Coenye, T; De Witte, E; Honraet, K; Nelis, HJ; Rigole, P; Rossel, B1
Bao, YJ; Chen, QQ; Chen, XF; Huang, YJ; Zhang, W; Zhu, W1
Feng, D; He, J; Peng, Y; Qi, H; Sun, J; Wan, P; Wang, J; Zha, W; Zhou, J; Zhu, X; Zhu, Y1
Cui, TB; Liu, ZY; Shao, L; Zhao, SJ; Zhao, W1
Chen, L; Liang, B; Zhang, Y1
Jílek, R; Olejníčková, J; Sotolář, R; Tříska, J; Vrchotová, N1
He, YD; Lin, QX; Liu, YT; Ren, XL; Wang, LY; Ye, XY; Zhang, Y; Zhu, J1
Deng, ZF; Hou, XL; Li, RP; Sun, MX; Sun, Y; Wang, ZZ; Xiao, K1
Qin, J; Shi, W; Wen, H1
Chen, JZ; Chen, S; Fan, J; Fan, JZ; He, QZ; Liu, J; Luo, ZJ; Meng, GL; Yang, L; Zhang, JK1
Huang, H; Huang, J; Huang, K; Liu, P; Peng, J; Shen, X; Xie, X1
Hao, W; Li, S; Xu, CY; Zhang, RL1
Liu, L; Yu, R; Zhang, M; Zhou, L1
Baek, NI; Cha, J; Choi, KH; Hwang, S; Kim, J; Park, H; Yang, SJ1
Hu, N; Jiang, XX; Li, B; Li, J; Miao, Q; Miao, S; Shi, XP; Wang, SW; Ye, MX; Zhang, J; Zhang, S1
Tan, Y; Yao, F; Zhang, J; Zhang, Q1
Hong, Y; Kong, LD; Li, Z; Liu, L; Liu, YL; Shi, YW; Wang, CP; Wang, X1
Hamada, H; Imai, H; Ishihara, K; Kitagawa, M; Masuoka, N; Nakajima, N; Shimoda, K1
Andres-Lacueva, C; Escribano, E; Estruch, R; Rotches-Ribalta, M; Urpi-Sarda, M1
Deng, J; Dong, M; Liu, J; Liu, W; Wang, Y; Zheng, M1
Guo, G; Liu, LT; Wu, M; Zhang, WG1
Herath, W; Khan, IA; Khan, SI1
Cartenì, M; Cozza, V; De Filippis, A; De Maria, S; Donnarumma, G; Petrazzuolo, M; Ravagnan, G; Tufano, MA1
Chen, X; Li, J; Liu, J; Liu, Z; Lv, J; Mo, X; Yang, C; Yuan, M1
Duan, J; Gan, W; Han, X; Ling, S; Sun, L; Xu, JW1
He, K; Jiang, YP; Peng, C; Tang, JY; Xin, HL; Yu, CH; Zhang, H1
Hamada, H; Hori, YS; Horio, Y; Hosoda, R; Kuno, A; Ohtani, K; Oohiro, A; Wakamiya, N1
Chang, HW; Hwangbo, K; Im, JY; Jahng, Y; Kim, YJ; Lee, CS; Son, JK; Woo, MH; Zheng, MS1
Ito, H; Kawabe, S; Kimoto, M; Kirino, A; Nishi, A; Takasuka, Y; Tsuji, H; Yamashita, H1
Chen, L; Deng, X; He, Y; Lan, Z; Lin, Q; Lin, Y; Mi, X; Wei, L; Zhang, Y1
Gershenzon, J; Hammerbacher, A; Krokene, P; Li, SH; Nagy, NE; Niu, XM; Schneider, B1
Li, L; Li, Y; Xing, Y; Yu, S; Zhang, L; Zhang, R1
Fan, WJ; Ling, DY; Xu, XL; Zhang, W; Zhu, QY1
Du, X; Hou, Y; Li, M; Yang, Q; Yuan, M; Zhou, L; Zhou, Z1
Chen, X; Fan, W; Huang, C; Yao, W; Zhang, W; Zhong, H1
De Luca, C; Korkina, L; Kostyuk, VA; Lulli, D; Pastore, S; Potapovich, AI; Stancato, A1
Baek, NI; Cha, J; Kim, J; Lee, HS; Park, CS; Park, H; Park, JH1
Chang, MJ; Wang, JL; Wang, Y; Xiao, JH; Yan, YL; Yang, J1
Chen, Y; Song, R; Wang, X; Zhao, KS; Zhao, M1
Greger, H1
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de Luca, C; Korkina, LG; Kostyuk, TV; Kostyuk, VA; Potapovich, AI1
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Lo Monte, G; Marci, R; Soave, I1
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Reviews

33 review(s) available for glucose, (beta-d)-isomer and stilbenes

ArticleYear
[Progress in the pharmacological study of Chinese herbal drug: polygonum cuspidatum].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2000, Volume: 25, Issue:11

    Topics: Animals; Antineoplastic Agents, Phytogenic; Antiviral Agents; Cardiotonic Agents; Drugs, Chinese Herbal; Emodin; Glucosides; Plants, Medicinal; Platelet Aggregation Inhibitors; Polygonum; Stilbenes

2000
Pharmacological studies on resveratrol.
    Methods and findings in experimental and clinical pharmacology, 2003, Volume: 25, Issue:4

    Topics: Animals; Antineoplastic Agents; Apoptosis; Arachidonic Acid; Cell Degranulation; Chemical and Drug Induced Liver Injury; Glucosides; Humans; Hyperlipidemias; Hypolipidemic Agents; Lipid Peroxidation; Neoplasm Metastasis; Neutrophils; Phytotherapy; Polygonum; Resveratrol; Stilbenes

2003
[Progress of study on brain protective effect and mechanism of Polygonum multiflorum].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2005, Volume: 25, Issue:10

    Topics: Animals; Antioxidants; Calcium Channel Blockers; Drugs, Chinese Herbal; Glucosides; Humans; Learning Disabilities; Neuroprotective Agents; Plant Extracts; Polygonum; Stilbenes

2005
Inhibitors of microglial neurotoxicity: focus on natural products.
    Molecules (Basel, Switzerland), 2011, Jan-25, Volume: 16, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Benzyl Alcohols; Biological Products; Biphenyl Compounds; Catechin; Catechols; Curcumin; Encephalitis; Fatty Alcohols; Ginsenosides; Glucosides; Microglia; Molecular Structure; Nerve Degeneration; Neuroprotective Agents; Phenyl Ethers; Plant Extracts; Resveratrol; Stilbenes

2011
The immunomodulating activities of resveratrol glucosides in humans.
    Recent patents on food, nutrition & agriculture, 2011, Volume: 3, Issue:2

    Topics: Anti-Inflammatory Agents; Antioxidants; Glucosides; Humans; Immunologic Factors; Patents as Topic; Phytotherapy; Plant Extracts; Resveratrol; Stilbenes

2011
The progress of the research on cardio-vascular effects and acting mechanism of polydatin.
    Chinese journal of integrative medicine, 2012, Volume: 18, Issue:9

    Topics: Biomedical Research; Cardiovascular System; Glucosides; Humans; Lipid Peroxidation; Myocytes, Cardiac; Stilbenes; Vasodilation

2012
The diversity of Stemona stilbenoids as a result of storage and fungal infection.
    Journal of natural products, 2012, Dec-28, Volume: 75, Issue:12

    Topics: Antifungal Agents; Glucosides; Humans; Lipoxygenase Inhibitors; Molecular Structure; Oxidopamine; Stemonaceae; Stilbenes; Structure-Activity Relationship

2012
Polydatin: a review of pharmacology and pharmacokinetics.
    Pharmaceutical biology, 2013, Volume: 51, Issue:11

    Topics: Animals; Diet; Drugs, Chinese Herbal; Endothelial Cells; Glucosides; Humans; Liver; Lung; Myocytes, Cardiac; Neurons; Stilbenes

2013
Biocatalysis and biotransformation of resveratrol in microorganisms.
    Biotechnology letters, 2015, Volume: 37, Issue:1

    Topics: Acyltransferases; Biocatalysis; Biotransformation; Escherichia coli; Glucosides; Industrial Microbiology; Metabolic Engineering; Metabolic Networks and Pathways; Resveratrol; Saccharomyces cerevisiae; Stilbenes

2015
Biological Activities of 2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-Glucoside in Antiaging and Antiaging-Related Disease Treatments.
    Oxidative medicine and cellular longevity, 2016, Volume: 2016

    Topics: Aging; Animals; Cardiovascular Agents; Cellular Senescence; Disease Models, Animal; Drugs, Chinese Herbal; Fallopia multiflora; Gene Expression Regulation; Glucosides; Humans; Hypoglycemic Agents; Neuroprotective Agents; Phytotherapy; Plants, Medicinal; Signal Transduction; Stilbenes

2016
Impact of 2, 3, 5, 4'-tetrahydroxystilbene-2-O-β-D-glucoside on cognitive deficits in animal models of Alzheimer's disease: a systematic review.
    BMC complementary and alternative medicine, 2016, Aug-26, Volume: 16, Issue:1

    Topics: Alzheimer Disease; Animals; Cognition; Disease Models, Animal; Glucosides; Humans; Mice; Rats; Stilbenes

2016
Chinese Herbal Medicine for the Optimal Management of Polycystic Ovary Syndrome.
    The American journal of Chinese medicine, 2017, Volume: 45, Issue:3

    Topics: Androgens; Berberine; Drugs, Chinese Herbal; Female; Ginsenosides; Glucosides; Humans; Insulin Resistance; Monoterpenes; Phenanthrenes; Phytotherapy; Polycystic Ovary Syndrome; Resveratrol; Stilbenes; Theca Cells

2017
Current pharmacological developments in 2,3,4',5-tetrahydroxystilbene 2-O-β-D-glucoside (TSG).
    European journal of pharmacology, 2017, Sep-15, Volume: 811

    Topics: Aging; Animals; Cardiovascular System; Central Nervous System; Glucosides; Humans; Stilbenes

2017
Therapeutic applications of resveratrol and its derivatives on periodontitis.
    Annals of the New York Academy of Sciences, 2017, Volume: 1403, Issue:1

    Topics: Anti-Inflammatory Agents; Fibroblasts; Glucosides; Humans; Periodontitis; Porphyromonas gingivalis; Resveratrol; Stilbenes; Treatment Outcome

2017
[Recent advances in anti-aging study of 2,3,5,4'-tetrahydroxystilbene-2-O-beta-D-glucopyranoside--a main component of Polygonum multiflorum].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2016, Volume: 41, Issue:2

    Topics: Aging; Animals; Drugs, Chinese Herbal; Glucosides; Humans; Polygonum; Stilbenes

2016
The protective mechanisms of polydatin in cerebral ischemia.
    European journal of pharmacology, 2019, Jan-05, Volume: 842

    Topics: Animals; Brain Ischemia; Glucosides; Humans; Neuroprotective Agents; Stilbenes

2019
Biological Effects of Tetrahydroxystilbene Glucoside: An Active Component of a Rhizome Extracted from
    Oxidative medicine and cellular longevity, 2018, Volume: 2018

    Topics: Animals; Antioxidants; Biological Products; Cytoprotection; Glucosides; Humans; Plant Extracts; Polygonum; Rhizome; Stilbenes

2018
Protective effects of polydatin on multiple organ ischemia-reperfusion injury.
    Bioorganic chemistry, 2020, Volume: 94

    Topics: Animals; Drugs, Chinese Herbal; Fallopia japonica; Glucosides; Humans; Medicine, Chinese Traditional; Molecular Conformation; Protective Agents; Reperfusion Injury; Stilbenes

2020
A review on the extraction, purification, detection, and pharmacological effects of 2,3,5,4'-tetrahydroxystilbene-2-O-β-d-glucoside from Polygonum multiflorum.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020, Volume: 124

    Topics: Animals; Fallopia multiflora; Glucosides; Humans; Medicine, Chinese Traditional; Stilbenes

2020
Insights into pharmacological mechanisms of polydatin in targeting risk factors-mediated atherosclerosis.
    Life sciences, 2020, Aug-01, Volume: 254

    Topics: Anticholesteremic Agents; Atherosclerosis; Cholesterol, LDL; Endothelial Cells; Fallopia japonica; Glucosides; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hyperlipidemias; Lipoproteins, LDL; Plaque, Atherosclerotic; Receptors, LDL; Risk Factors; Stilbenes

2020
Polydatin for treating atherosclerotic diseases: A functional and mechanistic overview.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020, Volume: 128

    Topics: Animals; Anti-Inflammatory Agents; Anticholesteremic Agents; Antioxidants; Arteries; Atherosclerosis; Cardiovascular Agents; Glucosides; Humans; Inflammation Mediators; Lipid Metabolism; Oxidative Stress; Plaque, Atherosclerotic; Signal Transduction; Stilbenes

2020
Protective Effects of Polydatin Against Dementia-Related Disorders.
    Current neuropharmacology, 2021, Volume: 19, Issue:2

    Topics: Alzheimer Disease; Dementia; Glucosides; Humans; Lewy Body Disease; Stilbenes

2021
Nonhormonal Treatment for Endometriosis Focusing on Redox Imbalance.
    Gynecologic and obstetric investigation, 2021, Volume: 86, Issue:1-2

    Topics: Animals; Antioxidants; Cabergoline; Dopamine Agonists; Endometriosis; Female; Glucosides; Humans; Methemoglobin; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Resveratrol; Signal Transduction; Simvastatin; Stilbenes; Superoxides

2021
SIRT1 provides new pharmacological targets for polydatin through its role as a metabolic sensor.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 139

    Topics: Animals; Glucosides; Humans; Inflammasomes; Metabolism; Platelet Aggregation Inhibitors; Signal Transduction; Sirtuin 1; Stilbenes

2021
The Neuroprotective Role of Polydatin: Neuropharmacological Mechanisms, Molecular Targets, Therapeutic Potentials, and Clinical Perspective.
    Molecules (Basel, Switzerland), 2021, Oct-02, Volume: 26, Issue:19

    Topics: Animals; Cognition Disorders; Drug Delivery Systems; Glucosides; Humans; Neurodegenerative Diseases; Neuroprotective Agents; Spinal Cord Injuries; Stilbenes; Stroke

2021
Old dog, new tricks: Polydatin as a multitarget agent for current diseases.
    Phytotherapy research : PTR, 2022, Volume: 36, Issue:1

    Topics: Apoptosis; Drugs, Chinese Herbal; Glucosides; Stilbenes

2022
Polydatin: A Critical Promising Natural Agent for Liver Protection via Antioxidative Stress.
    Oxidative medicine and cellular longevity, 2022, Volume: 2022

    Topics: Animals; Antioxidants; Glucosides; Humans; Liver; Oxidative Stress; Stilbenes

2022
Looking for Responders among Women with Chronic Pelvic Pain Treated with a Comicronized Formulation of Micronized Palmitoylethanolamide and Polydatin.
    BioMed research international, 2022, Volume: 2022

    Topics: Amides; Chronic Pain; Dysmenorrhea; Endometriosis; Ethanolamines; Female; Glucosides; Humans; Palmitic Acids; Pelvic Pain; Stilbenes

2022
Polydatin as a therapeutic alternative for central nervous system disorders: A systematic review of animal studies.
    Phytotherapy research : PTR, 2022, Volume: 36, Issue:7

    Topics: Animals; Glucosides; Male; Neuroprotective Agents; Parkinson Disease; Stilbenes

2022
Pharmacological effects of polydatin in the treatment of metabolic diseases: A review.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2022, Jul-20, Volume: 102

    Topics: AMP-Activated Protein Kinases; Atherosclerosis; Diabetes Mellitus; Glucosides; Gout; Humans; Non-alcoholic Fatty Liver Disease; Obesity; Phosphatidylinositol 3-Kinases; Quality of Life; Stilbenes

2022
The melanin inhibitory effect of plants and phytochemicals: A systematic review.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2022, Volume: 107

    Topics: Acetates; Acrolein; Animals; Arbutin; Bleaching Agents; Cell Line, Tumor; Curcumin; Emodin; Flavonoids; Ginsenosides; Glucosides; Humans; Hydroxybenzoates; Melanins; Microphthalmia-Associated Transcription Factor; Monophenol Monooxygenase; Phytochemicals; Plant Extracts; Pterocarpans; Stilbenes; Transcription Factors

2022
Polydatin: Pharmacological Mechanisms, Therapeutic Targets, Biological Activities, and Health Benefits.
    Molecules (Basel, Switzerland), 2022, Oct-01, Volume: 27, Issue:19

    Topics: Female; Glucosides; Humans; Polyphenols; Resveratrol; Stilbenes

2022
Uncovering the Anticancer Potential of Polydatin: A Mechanistic Insight.
    Molecules (Basel, Switzerland), 2022, Oct-23, Volume: 27, Issue:21

    Topics: Breast Neoplasms; Female; Glucosides; Humans; Signal Transduction; Stilbenes

2022

Trials

8 trial(s) available for glucose, (beta-d)-isomer and stilbenes

ArticleYear
Inhibition of low-density lipoprotein oxidation by Nagano purple grape (Vitis viniferaxVitis labrusca).
    Journal of nutritional science and vitaminology, 2009, Volume: 55, Issue:6

    Topics: Adult; Anthocyanins; Antioxidants; Cholesterol, LDL; Fruit; Glucosides; Humans; Lipid Peroxidation; Male; Middle Aged; Plant Preparations; Resveratrol; Stilbenes; Vitis

2009
Effectiveness of the association micronized N-Palmitoylethanolamine (PEA)-transpolydatin in the treatment of chronic pelvic pain related to endometriosis after laparoscopic assessment: a pilot study.
    European journal of obstetrics, gynecology, and reproductive biology, 2011, Volume: 158, Issue:1

    Topics: Adult; Amides; Analgesics; Double-Blind Method; Endocannabinoids; Endometriosis; Ethanolamines; Female; Glucosides; Humans; Laparoscopy; Palmitic Acids; Pelvic Pain; Phytotherapy; Pilot Projects; Stilbenes; Treatment Outcome; Young Adult

2011
Pharmacokinetics of resveratrol metabolic profile in healthy humans after moderate consumption of red wine and grape extract tablets.
    Pharmacological research, 2012, Volume: 66, Issue:5

    Topics: Adult; Dietary Supplements; Glucosides; Humans; Male; Plant Extracts; Resveratrol; Stilbenes; Tablets; Vitis; Wine; Young Adult

2012
Vestibulodynia: synergy between palmitoylethanolamide + transpolydatin and transcutaneous electrical nerve stimulation.
    Journal of lower genital tract disease, 2013, Volume: 17, Issue:2

    Topics: Administration, Oral; Adolescent; Adult; Amides; Analgesics; Drug Synergism; Endocannabinoids; Ethanolamines; Female; Glucosides; Humans; Middle Aged; Palmitic Acids; Placebos; Stilbenes; Transcutaneous Electric Nerve Stimulation; Treatment Outcome; Vulvodynia; Young Adult

2013
[Administration of micronized palmitoylethanolamide (PEA)-transpolydatin in the treatment of chronic pelvic pain in women affected by endometriosis: preliminary results].
    Minerva ginecologica, 2013, Volume: 65, Issue:4

    Topics: Adult; Amides; Anti-Inflammatory Agents, Non-Steroidal; Chronic Pain; Drug Combinations; Dysmenorrhea; Dyspareunia; Endocannabinoids; Endometriosis; Ethanolamines; Female; Glucosides; Humans; Middle Aged; Palmitic Acids; Particle Size; Pelvic Pain; Pilot Projects; Quality of Life; Stilbenes; Surveys and Questionnaires; Young Adult

2013
Effectiveness of the Association N-Palmitoylethanolamine and Transpolydatin in the Treatment of Primary Dysmenorrhea.
    Journal of pediatric and adolescent gynecology, 2015, Volume: 28, Issue:6

    Topics: Adolescent; Adult; Amides; Analgesics; Drug Therapy, Combination; Dysmenorrhea; Ethanolamines; Female; Follow-Up Studies; Glucosides; Humans; Italy; Pain Measurement; Palmitic Acids; Pelvic Pain; Pregnancy; Stilbenes; Treatment Outcome; Young Adult

2015
Randomised clinical trial: the analgesic properties of dietary supplementation with palmitoylethanolamide and polydatin in irritable bowel syndrome.
    Alimentary pharmacology & therapeutics, 2017, Volume: 45, Issue:7

    Topics: Abdominal Pain; Adult; Amides; Analgesics; Cell Count; Dietary Supplements; Double-Blind Method; Ethanolamines; Female; Glucosides; Humans; Irritable Bowel Syndrome; Male; Mast Cells; Middle Aged; Palmitic Acids; Stilbenes; Young Adult

2017
Antioxidant Activity with Increased Endogenous Levels of Vitamin C, E and A Following Dietary Supplementation with a Combination of Glutathione and Resveratrol Precursors.
    Nutrients, 2020, Oct-22, Volume: 12, Issue:11

    Topics: Acetylcysteine; Aged; Alanine; Antioxidants; Ascorbic Acid; Dietary Supplements; Erythrocytes; Female; Glucosides; Glutamine; Glutathione; Glycine; Humans; Ketoglutaric Acids; Male; Middle Aged; Neopterin; Oxidation-Reduction; Resveratrol; Stilbenes; Sulfhydryl Compounds; Vitamin A; Vitamin E; Vitamins

2020

Other Studies

704 other study(ies) available for glucose, (beta-d)-isomer and stilbenes

ArticleYear
[A new stilbene glucoside from Chinese crude drug "Heshouwu," the roots of Polygonum multiflorum Thunb (author's transl)].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1975, Volume: 95, Issue:2

    Topics: Glucosides; Glycosides; Medicine, Chinese Traditional; Medicine, East Asian Traditional; Plants, Medicinal; Stilbenes

1975
[Pharmacological intervention in experimental multiple organ failure in rats].
    Zhonghua zheng xing shao shang wai ke za zhi = Zhonghua zheng xing shao shang waikf [i.e. waike] zazhi = Chinese journal of plastic surgery and burns, 1992, Volume: 8, Issue:1

    Topics: Allopurinol; Animals; Antioxidants; Free Radicals; Fructose-Bisphosphatase; Glucosides; Glutathione Peroxidase; Male; Malondialdehyde; Multiple Organ Failure; Oxygen; Rats; Rats, Inbred Strains; Stilbenes; Superoxide Dismutase

1992
[Assay of stilbene glucoside in Polygonum multiflorum Thunb and its processed products].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 1991, Volume: 16, Issue:8

    Topics: Drugs, Chinese Herbal; Glucosides; Hot Temperature; Spectrophotometry, Ultraviolet; Stilbenes; Technology, Pharmaceutical

1991
[Influences of 3,4,5-trihydroxystibene-3-beta-mono-D-glucoside on rabbits' platelet aggregation and thromboxane B2 production in vitro].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1990, Volume: 11, Issue:6

    Topics: Animals; Dose-Response Relationship, Drug; Female; Glucosides; In Vitro Techniques; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Stilbenes; Thromboxane B2

1990
[Influences of 3,4,5-trihydroxystibene-3-beta-mono-D-glucoside on beat rate and injury of cultured newborn rat myocardial cells].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1990, Volume: 11, Issue:2

    Topics: Animals; Cells, Cultured; Drugs, Chinese Herbal; Glucosides; L-Lactate Dehydrogenase; Myocardium; Nisoldipine; Phentolamine; Platelet Aggregation Inhibitors; Propranolol; Rats; Stilbenes

1990
Impermeant stilbene disulfonic acids block chemotactic peptide receptor function on human granulocytes.
    Inflammation, 1989, Volume: 13, Issue:1

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Calcimycin; Cell Aggregation; Granulocytes; Humans; In Vitro Techniques; Ion Channels; N-Formylmethionine Leucyl-Phenylalanine; Receptors, Formyl Peptide; Receptors, Immunologic; Stilbenes; Superoxides; Tetradecanoylphorbol Acetate; Zymosan

1989
[Effects of polydatin on platelet aggregation in rabbits].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1988, Volume: 23, Issue:5

    Topics: Animals; Drugs, Chinese Herbal; Female; Glucosides; Glycosides; Male; Platelet Aggregation Inhibitors; Rabbits; Stilbenes

1988
Inhibition of complement-mediated functions of human neutrophils by impermeant stilbene disulfonic acids.
    Journal of immunology (Baltimore, Md. : 1950), 1981, Volume: 126, Issue:5

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Complement C3b; Complement System Proteins; Dose-Response Relationship, Immunologic; Humans; Neutrophils; Opsonin Proteins; Phagocytosis; Receptors, Complement; Rosette Formation; Stilbenes; Superoxides; Time Factors; Zymosan

1981
[A preliminary study of the correlation between phylogeny, chemical constituents and therapeutic effects of Rheum species].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1980, Volume: 15, Issue:1

    Topics: Anthraquinones; Glucosides; Phylogeny; Plants, Medicinal; Senna Extract; Sennosides; Species Specificity; Stilbenes

1980
Potent inhibitors of tyrosinase activity and melanin biosynthesis from Rheum officinale.
    Planta medica, 1995, Volume: 61, Issue:5

    Topics: Enzyme Inhibitors; Glucosides; Melanins; Monophenol Monooxygenase; Plants, Medicinal; Rheum; Spectrometry, Mass, Fast Atom Bombardment; Stilbenes

1995
Reducing effect of 3,4',5-trihydroxystibene-3-beta-mono-D-glucoside on arterial thrombosis induced by vascular endothelial injury.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1995, Volume: 16, Issue:2

    Topics: Animals; Carotid Artery Thrombosis; Endothelium, Vascular; Female; Glucosides; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Stilbenes; Thromboxane B2

1995
Influence of 3,4',5-trihydroxystibene-3-beta-mono-D-glucoside on vascular endothelial epoprostenol and platelet aggregation.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1995, Volume: 16, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Drugs, Chinese Herbal; Endothelium, Vascular; Glucosides; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Stilbenes; Thromboxane B2; Umbilical Veins

1995
Novel Ca(2+)-ATPase inhibitors from the dried root tubers of Polygonum Multiflorum.
    Journal of natural products, 1994, Volume: 57, Issue:12

    Topics: Australia; Benzofurans; Ca(2+) Mg(2+)-ATPase; Calcium-Transporting ATPases; Erythrocytes; Glucosides; Humans; In Vitro Techniques; Plant Roots; Plants, Medicinal; Stilbenes

1994
[Polydatin prevents endotoxin-induced acute lung injury in rats].
    Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 1993, Volume: 16, Issue:3

    Topics: Animals; Drugs, Chinese Herbal; Endotoxins; Escherichia coli; Female; Glucosides; Lung; Male; Rats; Rats, Sprague-Dawley; Respiratory Distress Syndrome; Stilbenes

1993
Two new 2-arylbenzofuran derivatives from hypoglycemic activity-bearing fractions of Morus insignis.
    Chemical & pharmaceutical bulletin, 1993, Volume: 41, Issue:7

    Topics: Animals; Benzofurans; Blood Glucose; Child, Preschool; Diabetes Mellitus, Experimental; Glucosides; Humans; Hypoglycemic Agents; Male; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Resorcinols; Stilbenes

1993
Antihyperglycemic activity of phenolics from Pterocarpus marsupium.
    Journal of natural products, 1997, Volume: 60, Issue:6

    Topics: Animals; Benzofurans; Blood Glucose; Body Weight; Cresols; Diabetes Mellitus, Experimental; Female; Glucosides; Hypoglycemic Agents; Male; Metformin; Phenols; Plants, Medicinal; Rats; Stilbenes; Wood

1997
Synthesis of biologically active polyphenolic glycosides (combretastatin and resveratrol series).
    Carbohydrate research, 1997, Jun-20, Volume: 301, Issue:3-4

    Topics: Antineoplastic Agents; Bibenzyls; Cell Division; Ganglia, Spinal; Glucosides; Glycosylation; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mitosis; Molecular Structure; Platelet Aggregation Inhibitors; Resveratrol; Stilbenes; Tumor Cells, Cultured

1997
Isolation, synthesis, and antiplatelet aggregation activity of resveratrol 3-O-beta-D-glucopyranoside and related compounds.
    Journal of natural products, 1997, Volume: 60, Issue:11

    Topics: Glucosides; Humans; In Vitro Techniques; Magnetic Resonance Spectroscopy; Platelet Aggregation; Platelet Aggregation Inhibitors; Seeds; Stilbenes

1997
Contents of resveratrol, piceid, and their isomers in commercially available wines made from grapes cultivated in Japan.
    Bioscience, biotechnology, and biochemistry, 1997, Volume: 61, Issue:11

    Topics: Chromatography, High Pressure Liquid; Glucosides; Isomerism; Japan; Reproducibility of Results; Resveratrol; Rosales; Stilbenes; Wine

1997
Biotransformation of resveratrol to piceid by Bacillus cereus.
    Journal of natural products, 1998, Volume: 61, Issue:10

    Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Bacillus cereus; Biotransformation; Enzyme Inhibitors; Glucosides; Models, Biological; Molecular Structure; Platelet Aggregation Inhibitors; Resveratrol; Stilbenes

1998
Inhibitory effects of resveratrol analogs on unopsonized zymosan-induced oxygen radical production.
    Biochemical pharmacology, 1999, Mar-15, Volume: 57, Issue:6

    Topics: Adult; Animals; Antioxidants; Cell Line; Dose-Response Relationship, Drug; Humans; Luminescent Measurements; Mice; Monocytes; Neutrophils; Reactive Oxygen Species; Resveratrol; Stilbenes; Zymosan

1999
High-performance liquid chromatography coupled with fluorescence detection for the determination of trans-astringin in wine.
    Journal of chromatography. A, 1999, Jul-23, Volume: 849, Issue:2

    Topics: Chromatography, High Pressure Liquid; Glucosides; Spectrometry, Fluorescence; Stilbenes; Wine

1999
Piceid, the major resveratrol derivative in grape juices.
    Journal of agricultural and food chemistry, 1999, Volume: 47, Issue:4

    Topics: Beverages; Glucosides; Molecular Structure; Platelet Aggregation Inhibitors; Resveratrol; Rosales; Species Specificity; Stereoisomerism; Stilbenes

1999
Isolation and identification of stilbenes in two varieties of Polygonum cuspidatum.
    Journal of agricultural and food chemistry, 2000, Volume: 48, Issue:2

    Topics: Chromatography, High Pressure Liquid; Glucosides; Magnetic Resonance Spectroscopy; Plant Roots; Polygonaceae; Resveratrol; Stilbenes

2000
Effects of stilbene constituents from rhubarb on nitric oxide production in lipopolysaccharide-activated macrophages.
    Bioorganic & medicinal chemistry letters, 2000, Feb-21, Volume: 10, Issue:4

    Topics: Anthraquinones; Emodin; Gallic Acid; Glucosides; Lipopolysaccharides; Macrophage Activation; Macrophages; Naphthalenes; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Plant Extracts; Plants, Medicinal; Rheum; Stilbenes; Structure-Activity Relationship

2000
Evidence for the stimulatory effect of resveratrol on Ca(2+)-activated K+ current in vascular endothelial cells.
    Cardiovascular research, 2000, Volume: 45, Issue:4

    Topics: Cell Line; Cytoskeletal Proteins; Dose-Response Relationship, Drug; Endothelium, Vascular; Glucosides; Humans; Ion Channel Gating; Islets of Langerhans; Patch-Clamp Techniques; Paxillin; Peptides; Phosphoproteins; Potassium Channel Blockers; Potassium Channels; Stilbenes; Stimulation, Chemical; Umbilical Veins; Vasodilator Agents

2000
Constitutive accumulation of a resveratrol-glucoside in transgenic alfalfa increases resistance to Phoma medicaginis.
    Molecular plant-microbe interactions : MPMI, 2000, Volume: 13, Issue:5

    Topics: Acyltransferases; Ascomycota; Base Sequence; Chromatography, High Pressure Liquid; DNA Primers; Glucosides; Magnetic Resonance Spectroscopy; Medicago sativa; Plants, Genetically Modified; Resveratrol; RNA, Messenger; Stilbenes

2000
Oligostilbenoids in stem bark of Vatica rassak.
    Phytochemistry, 2000, Volume: 54, Issue:1

    Topics: Benzofurans; Glucosides; Plant Extracts; Plant Stems; Resveratrol; Stilbenes; Trees

2000
Metabolism of rhaponticin and chrysophanol 8-o-beta-D-glucopyranoside from the rhizome of rheum undulatum by human intestinal bacteria and their anti-allergic actions.
    Biological & pharmaceutical bulletin, 2000, Volume: 23, Issue:7

    Topics: Animals; Anthraquinones; Anti-Allergic Agents; Bacteria; Glucosides; Guinea Pigs; Histamine; Hyaluronoglucosaminidase; Intestines; Male; Mast Cells; Mice; Mice, Inbred ICR; Passive Cutaneous Anaphylaxis; Peritoneal Cavity; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Rheum; Stilbenes

2000
A stilbene and dihydrochalcones with radical scavenging activities from Loiseleuria procumbens.
    Phytochemistry, 2000, Volume: 54, Issue:8

    Topics: Chalcone; Free Radical Scavengers; Glucosides; Magnoliopsida; Stilbenes

2000
Isolation and characterization of novel stilbene derivatives from Riesling wine.
    Journal of agricultural and food chemistry, 2000, Volume: 48, Issue:7

    Topics: Antioxidants; Dimerization; Glucosides; Magnetic Resonance Spectroscopy; Mass Spectrometry; Models, Chemical; Resveratrol; Stilbenes; Wine

2000
Effect of postharvest ultraviolet irradiation on resveratrol and other phenolics of cv. Napoleon table grapes.
    Journal of agricultural and food chemistry, 2000, Volume: 48, Issue:10

    Topics: Anthocyanins; Antioxidants; Chromatography, High Pressure Liquid; Glucosides; Phenols; Resveratrol; Rosales; Stilbenes; Ultraviolet Rays

2000
Effects of naturally occurring stilbene glucosides from medicinal plants and wine, on tumour growth and lung metastasis in Lewis lung carcinoma-bearing mice.
    The Journal of pharmacy and pharmacology, 2000, Volume: 52, Issue:10

    Topics: Animals; Antineoplastic Agents; Carcinoma, Lewis Lung; Cattle; DNA; Drug Screening Assays, Antitumor; Endothelium, Vascular; Female; Glucosides; Humans; Mice; Mice, Inbred C57BL; Organ Size; Phytotherapy; Plants, Medicinal; Resveratrol; Ribonucleotide Reductases; Spleen; Stilbenes; Swine; T-Lymphocytes; Thymus Gland; Umbilical Veins; Wine

2000
Method for the quantitative extraction of resveratrol and piceid isomers in grape berry skins. Effect of powdery mildew on the stilbene content.
    Journal of agricultural and food chemistry, 2001, Volume: 49, Issue:1

    Topics: Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Botrytis; Glucosides; Mitosporic Fungi; Plant Diseases; Platelet Aggregation Inhibitors; Resveratrol; Rosales; Stilbenes

2001
Two new stilbene dimer glucosides from grape (Vitis vinifera) cell cultures.
    Journal of natural products, 2001, Volume: 64, Issue:1

    Topics: Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Glucosides; Isoenzymes; Magnetic Resonance Spectroscopy; Mass Spectrometry; Prostaglandin-Endoperoxide Synthases; Rosales; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Stilbenes

2001
Antioxidant constituents from rhubarb: structural requirements of stilbenes for the activity and structures of two new anthraquinone glucosides.
    Bioorganic & medicinal chemistry, 2001, Volume: 9, Issue:1

    Topics: Animals; Anthraquinones; Antioxidants; Erythrocyte Membrane; Free Radical Scavengers; Glucosides; Lipid Peroxidation; Molecular Structure; Plants, Medicinal; Rabbits; Rheum; Stilbenes

2001
High-speed counter-current chromatography separation and purification of resveratrol and piceid from Polygonum cuspidatum.
    Journal of chromatography. A, 2001, Jan-12, Volume: 907, Issue:1-2

    Topics: Chromatography, High Pressure Liquid; Chromatography, Liquid; Glucosides; Isomerism; Magnetic Resonance Spectroscopy; Polygonaceae; Resveratrol; Spectrometry, Mass, Electrospray Ionization; Stilbenes

2001
Resveratrol and piceid levels in natural and blended peanut butters.
    Journal of agricultural and food chemistry, 2000, Volume: 48, Issue:12

    Topics: Absorption; Arachis; Chromatography, High Pressure Liquid; Food Handling; Glucosides; Platelet Aggregation Inhibitors; Resveratrol; Stilbenes

2000
Serum amyloid P component binds to Fc gamma receptors and opsonizes particles for phagocytosis.
    Journal of immunology (Baltimore, Md. : 1950), 2001, Jun-01, Volume: 166, Issue:11

    Topics: Androstadienes; Animals; COS Cells; Enzyme Inhibitors; Fluorescein-5-isothiocyanate; Humans; Microspheres; Neutrophils; Opsonin Proteins; Phagocytosis; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoinositide Phospholipase C; Protein Binding; Receptors, IgG; Serum Amyloid P-Component; Stilbenes; Transfection; Type C Phospholipases; Wortmannin; Zymosan

2001
[Chemical constituents of Rheum wittrochii Lundstr(II)].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 1998, Volume: 23, Issue:8

    Topics: Drugs, Chinese Herbal; Glucosides; Molecular Structure; Rheum; Stilbenes

1998
Induction of apoptosis by 3,4'-dimethoxy-5-hydroxystilbene in human promyeloid leukemic HL-60 cells.
    Planta medica, 2002, Volume: 68, Issue:2

    Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Caspase 3; Caspase 8; Caspase 9; Caspase Inhibitors; Caspases; Cell Division; Cytochrome c Group; DNA Fragmentation; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Gene Expression; Glucosides; HL-60 Cells; Humans; Mitochondria; Plant Extracts; Polygonum; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Stilbenes

2002
Galloylated catechins and stilbene diglucosides in Vitis vinifera cell suspension cultures.
    Phytochemistry, 2002, Volume: 60, Issue:8

    Topics: Biflavonoids; Carbohydrate Conformation; Catechin; Cells, Cultured; Glucosides; Proanthocyanidins; Spectrum Analysis; Stilbenes; Vitis

2002
Diptoindonesin A, a new C-glucoside of epsilon-viniferin from Shorea seminis (Dipterocarpaceae).
    Fitoterapia, 2002, Volume: 73, Issue:6

    Topics: Benzofurans; Ericales; Glucosides; Humans; Magnetic Resonance Spectroscopy; Phytotherapy; Plant Bark; Plant Extracts; Stilbenes

2002
The radical scavenging effects of stilbene glucosides from Polygonum multiflorum.
    Archives of pharmacal research, 2002, Volume: 25, Issue:5

    Topics: Free Radical Scavengers; Glucosides; Plant Bark; Plant Extracts; Polygonum; Stilbenes

2002
Capillary electrophoresis determination, synthesis, and stability of resveratrol and related 3-O-beta-D-glucopyranosides.
    Journal of agricultural and food chemistry, 2002, Dec-04, Volume: 50, Issue:25

    Topics: Drug Stability; Electrophoresis, Capillary; Glucosides; Resveratrol; Stilbenes; Wine

2002
Protective effect of polydatin against lipopolysaccharide-induced myocardial injury.
    Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA, 2003, Volume: 23, Issue:4

    Topics: Animals; Cardiomyopathies; Drug Interactions; Glucosides; Heart; Lipopolysaccharides; Myocytes, Cardiac; Protective Agents; Rats; Rats, Sprague-Dawley; Stilbenes; Stress Fibers

2003
[Determination of piceid in commercial Rhizoma Polygoni Cuspidati by HPLC].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2002, Volume: 27, Issue:5

    Topics: Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Glucosides; Plant Roots; Plants, Medicinal; Polygonum; Quality Control; Rhizome; Species Specificity; Stilbenes

2002
Feeding response of Ips paraconfusus to phloem and phloem metabolites of Heterobasidion annosum-inoculated ponderosa pine, Pinus ponderosa.
    Journal of chemical ecology, 2003, Volume: 29, Issue:5

    Topics: Animals; Basidiomycota; Biological Assay; Carbohydrates; Coleoptera; Coumaric Acids; Feeding Behavior; Glucosides; Male; Pinus; Pinus ponderosa; Plant Extracts; Plant Leaves; Population Dynamics; Stilbenes

2003
Effect of resveratrol on some activities of isolated and in whole blood human neutrophils.
    Physiological research, 2003, Volume: 52, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemotaxis; Dose-Response Relationship, Drug; Humans; Hypochlorous Acid; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitrites; Resveratrol; Stilbenes; Superoxides; Zymosan

2003
[Effect of polydatin on lipopolysaccharide-induced leucocyte chemotaxis].
    Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA, 2003, Volume: 23, Issue:12

    Topics: Animals; Chemotaxis, Leukocyte; Dose-Response Relationship, Drug; Glucosides; Lipopolysaccharides; Neutrophils; Rats; Rats, Sprague-Dawley; Stilbenes

2003
The mechanism of Polydatin in shock treatment.
    Clinical hemorheology and microcirculation, 2003, Volume: 29, Issue:3-4

    Topics: Animals; Calcium Channel Blockers; Calcium Signaling; Cell Adhesion; Cells, Cultured; Drug Evaluation, Preclinical; Endothelial Cells; Endothelium, Vascular; Fallopia japonica; Glucosides; Humans; Intercellular Adhesion Molecule-1; Leukocytes; Microcirculation; Muscle, Smooth, Vascular; Myocardium; Patch-Clamp Techniques; Phytotherapy; Plants, Medicinal; Potassium Channels; Rats; Shock, Hemorrhagic; Shock, Septic; Stilbenes; Verapamil

2003
Phenylpropanoid glycosides from Orobanche caerulescens.
    Planta medica, 2004, Volume: 70, Issue:1

    Topics: Adult; Antioxidants; Cholesterol, LDL; Glucosides; Glycosides; Humans; Inhibitory Concentration 50; Lipid Peroxidation; Male; Orobanche; Phenols; Phytotherapy; Plant Components, Aerial; Plant Extracts; Resveratrol; Stilbenes

2004
[Determination of 2,3,5,4'-tetrahydroxystilbene-2-O-beta-D-glucoside in yangan oral liquid by HPLC].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2003, Volume: 28, Issue:2

    Topics: Chromatography, High Pressure Liquid; Drug Combinations; Drugs, Chinese Herbal; Glucosides; Plants, Medicinal; Polygonum; Quality Control; Stilbenes

2003
[Study on the metabolite of stilbene glucoside in mice by liquid chromatography tandem-mass spectrometry].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2003, Volume: 38, Issue:12

    Topics: Animals; Chromatography, Liquid; Female; Glucosides; Male; Mice; Plants, Medicinal; Polygonum; Spectrometry, Mass, Electrospray Ionization; Stilbenes

2003
Antioxidants in Sicilian wines: analytic and compositive aspects.
    Drugs under experimental and clinical research, 2003, Volume: 29, Issue:5-6

    Topics: Antioxidants; Chromatography, High Pressure Liquid; Glucosides; Microscopy, Electron; Resveratrol; Sicily; Stilbenes; Wine

2003
New stilbene derivatives from Calligonum leucocladum.
    Journal of natural products, 2004, Volume: 67, Issue:6

    Topics: Drug Resistance, Multiple; Glucosides; Methicillin Resistance; Molecular Structure; Oxacillin; Plants, Medicinal; Polygonaceae; Resveratrol; Staphylococcus aureus; Stilbenes; Uzbekistan

2004
Effect of polydatin on phospholipase A2 in lung tissues in rats with endotoxic shock.
    Chinese journal of traumatology = Zhonghua chuang shang za zhi, 2004, Volume: 7, Issue:4

    Topics: Analysis of Variance; Animals; Glucosides; Lung; Male; Phospholipases A; Phospholipases A2; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Shock, Septic; Stilbenes

2004
Determination of piceid and resveratrol in Spanish wines deriving from Monastrell (Vitis vinifera L.) grape variety.
    Journal of agricultural and food chemistry, 2004, Aug-25, Volume: 52, Issue:17

    Topics: Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Fruit; Glucosides; Magnetic Resonance Spectroscopy; Resveratrol; Spain; Stilbenes; Vitis; Wine

2004
Expression of the stilbene synthase (StSy) gene from grapevine in transgenic white poplar results in high accumulation of the antioxidant resveratrol glucosides.
    Transgenic research, 2004, Volume: 13, Issue:3

    Topics: Acyltransferases; Blotting, Northern; Blotting, Southern; Blotting, Western; Chromatography, High Pressure Liquid; DNA, Complementary; Gene Expression; Glucosides; Hydrolysis; Mass Spectrometry; Plants, Genetically Modified; Populus; Spectrophotometry, Ultraviolet; Stilbenes; Transformation, Genetic; Vitis

2004
[Expression of VEGF in endothelial cells and the effects of 2, 3, 5, 4'-tetrahydroxystilbene-2-O-beta-D-glucoside].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2004, Volume: 39, Issue:6

    Topics: Cells, Cultured; Endothelial Cells; Glucosides; Humans; Lysophosphatidylcholines; Plants, Medicinal; Polygonum; RNA, Messenger; Stilbenes; Umbilical Veins; Vascular Endothelial Growth Factor A

2004
Inhibiting effects of resveratrol and its glucoside piceid against Venturia inaequalis, the causal agent of apple scab.
    Journal of agricultural and food chemistry, 2005, Jan-26, Volume: 53, Issue:2

    Topics: Ascomycota; Chemical Phenomena; Chemistry, Physical; Fungicides, Industrial; Germination; Glucosides; Malus; Plant Diseases; Resveratrol; Solubility; Stilbenes

2005
Two new hepatoprotective stilbene glycosides from Acer mono leaves.
    Journal of natural products, 2005, Volume: 68, Issue:1

    Topics: Acer; Animals; Glucosides; Glycosides; Hepatocytes; Hydrogen Peroxide; Korea; Male; Plant Leaves; Plants, Medicinal; Quercetin; Rats; Rats, Wistar; Stilbenes

2005
Cellular uptake and efflux of trans-piceid and its aglycone trans-resveratrol on the apical membrane of human intestinal Caco-2 cells.
    Journal of agricultural and food chemistry, 2005, Feb-09, Volume: 53, Issue:3

    Topics: Biological Transport; Caco-2 Cells; Cell Membrane; Glucosides; Humans; Intestinal Mucosa; Kinetics; Membrane Glycoproteins; Membrane Transport Modulators; Membrane Transport Proteins; Monosaccharide Transport Proteins; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Propionates; Quinolines; Resveratrol; Sodium-Glucose Transporter 1; Stilbenes

2005
[Study on optimizing extraction process of root of Polygonum multiflorum].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2004, Volume: 29, Issue:3

    Topics: Antioxidants; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Ethanol; Glucosides; Plant Roots; Plants, Medicinal; Polygonum; Stilbenes; Technology, Pharmaceutical; Time Factors

2004
[Influence of process methods on contents of chemical component Radix Polygoni Multiflori].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2005, Volume: 30, Issue:5

    Topics: Emodin; Glucosides; Hot Temperature; Plant Roots; Plants, Medicinal; Polygonum; Stilbenes; Tannins; Technology, Pharmaceutical

2005
[Determination of the contents of resveratrols and piceids in wines by high performance liquid chromatography with solid phase extraction].
    Se pu = Chinese journal of chromatography, 2005, Volume: 23, Issue:1

    Topics: Chromatography, High Pressure Liquid; Glucosides; Indicators and Reagents; Resveratrol; Solid Phase Extraction; Stereoisomerism; Stilbenes; Wine

2005
Protective activities of stilbene glycosides from Acer mono leaves against H2O2-induced oxidative damage in primary cultured rat hepatocytes.
    Journal of agricultural and food chemistry, 2005, May-18, Volume: 53, Issue:10

    Topics: Acer; Animals; Antioxidants; Cells, Cultured; Glucosides; Hepatocytes; Hydrogen Peroxide; Oxidation-Reduction; Oxidative Stress; Plant Leaves; Rats; Stilbenes

2005
Determination of stilbenes in hop pellets from different cultivars.
    Journal of agricultural and food chemistry, 2005, May-18, Volume: 53, Issue:10

    Topics: Chromatography, High Pressure Liquid; Flavonoids; Glucosides; Humulus; Phenols; Polyphenols; Resveratrol; Species Specificity; Stilbenes

2005
Uptake of diet resveratrol into the human low-density lipoprotein. Identification and quantification of resveratrol metabolites by liquid chromatography coupled with tandem mass spectrometry.
    Analytical chemistry, 2005, May-15, Volume: 77, Issue:10

    Topics: Antioxidants; Calibration; Chromatography, Liquid; Diet; Glucosides; Glucuronides; Humans; Lipoproteins, LDL; Reproducibility of Results; Resveratrol; Sensitivity and Specificity; Stilbenes; Tandem Mass Spectrometry

2005
Determination of stilbenes (delta-viniferin, trans-astringin, trans-piceid, cis- and trans-resveratrol, epsilon-viniferin) in Brazilian wines.
    Journal of agricultural and food chemistry, 2005, Jul-13, Volume: 53, Issue:14

    Topics: Benzofurans; Brazil; Chromatography, High Pressure Liquid; Glucosides; Magnetic Resonance Spectroscopy; Resorcinols; Resveratrol; Stilbenes; Wine

2005
Dihydrostilbene derivatives from Glycyrrhiza glabra leaves.
    Journal of natural products, 2005, Volume: 68, Issue:7

    Topics: Apigenin; Flavanones; Glucosides; Glycyrrhiza; Italy; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plant Leaves; Plants, Medicinal; Stilbenes

2005
Simple and rapid method for cis- and trans-resveratrol and piceid isomers determination in wine by high-performance liquid chromatography using chromolith columns.
    Journal of chromatography. A, 2005, Sep-02, Volume: 1085, Issue:2

    Topics: Chromatography, High Pressure Liquid; Glucosides; Resveratrol; Stereoisomerism; Stilbenes; Wine

2005
[Study on the optimal harvesting time of Rumex gmelini by analyzing the contents of principal components].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2005, Volume: 30, Issue:11

    Topics: Anthraquinones; Emodin; Glucosides; Plant Roots; Plants, Medicinal; Principal Component Analysis; Quality Control; Resveratrol; Rumex; Seasons; Stilbenes

2005
Resveratrol glucoside (Piceid) synthesis in seeds of transgenic oilseed rape (Brassica napus L.).
    TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik, 2005, Volume: 111, Issue:8

    Topics: Acyltransferases; Blotting, Southern; Brassica napus; Breeding; Chromatography, High Pressure Liquid; DNA Primers; Enzyme-Linked Immunosorbent Assay; Gene Transfer Techniques; Glucosides; Plants, Genetically Modified; RNA Interference; Seeds; Stilbenes; Vitis

2005
Preparative isolation and purification of trans-3,5,4'-trihydroxystilbene-4'-O-beta-D-glucopyranoside and (+)catechin from Rheum tanguticum Maxim. ex Balf. using high-speed counter-current chromatography by stepwise elution and stepwise increasing the flo
    Journal of chromatography. A, 2005, Oct-28, Volume: 1092, Issue:2

    Topics: Catechin; Countercurrent Distribution; Glucosides; Magnetic Resonance Spectroscopy; Rheum; Spectrometry, Mass, Electrospray Ionization; Stilbenes

2005
[Determination of 2,3,5,4'-tetrahydroxystilbene-2-O-beta-D-glucoside in the traditional Chinese preparation by high performance liquid chromatography with chemiluminescence detection].
    Guang pu xue yu guang pu fen xi = Guang pu, 2005, Volume: 25, Issue:6

    Topics: Capsules; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Formaldehyde; Glucosides; Kinetics; Luminescence; Luminescent Measurements; Molecular Structure; Nitric Acid; Reproducibility of Results; Stilbenes; Tablets

2005
New stilbenoid glucosides isolated from Vitis vinifera cell suspension cultures (cv. Cabernet Sauvignon).
    Planta medica, 2005, Volume: 71, Issue:9

    Topics: Cell Culture Techniques; Cells, Cultured; Glucosides; Humans; Phytotherapy; Plant Extracts; Stilbenes; Vitis

2005
A validated HPLC method for the quantitative analysis of trans-resveratrol and trans-piceid in Hungarian wines.
    Journal of chromatographic science, 2005, Volume: 43, Issue:9

    Topics: Chromatography, High Pressure Liquid; Electrophoresis, Capillary; Glucosides; Mass Spectrometry; Reproducibility of Results; Resveratrol; Spectrophotometry, Ultraviolet; Stilbenes; Wine

2005
Role of peptide primary sequence in polyphenol-protein recognition: an example with neurotensin.
    Biochimica et biophysica acta, 2005, Nov-30, Volume: 1726, Issue:3

    Topics: Amino Acid Sequence; Flavonoids; Glucosides; Hydrolyzable Tannins; Models, Molecular; Neurotensin; Nuclear Magnetic Resonance, Biomolecular; Peptides; Phenols; Polyphenols; Proteins; Protons; Resveratrol; Stilbenes

2005
Reduction of atherosclerosis in cholesterol-fed rabbits and decrease of expressions of intracellular adhesion molecule-1 and vascular endothelial growth factor in foam cells by a water-soluble fraction of Polygonum multiflorum.
    Journal of pharmacological sciences, 2005, Volume: 99, Issue:3

    Topics: Animals; Atherosclerosis; Cholesterol; Cholesterol, Dietary; Foam Cells; Glucosides; Humans; Intercellular Adhesion Molecule-1; Male; Medicine, Chinese Traditional; Polygonum; Rabbits; Stilbenes; Triglycerides; U937 Cells; Vascular Endothelial Growth Factor A

2005
Preparative isolation and purification of five compounds from the Chinese medicinal herb Polygonum cuspidatum Sieb. et Zucc by high-speed counter-current chromatography.
    Journal of chromatography. A, 2005, Dec-02, Volume: 1097, Issue:1-2

    Topics: Anthracenes; Chromatography, High Pressure Liquid; Countercurrent Distribution; Emodin; Fallopia japonica; Glucosides; Glycosides; Molecular Structure; Plant Preparations; Reproducibility of Results; Resveratrol; Stilbenes

2005
HPLC determination of polydatin in rat biological matrices: application to pharmacokinetic studies.
    Journal of pharmaceutical and biomedical analysis, 2006, Apr-11, Volume: 41, Issue:1

    Topics: Animals; Calibration; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Glucosides; Methanol; Models, Chemical; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Stilbenes; Technology, Pharmaceutical; Ultraviolet Rays

2006
Antioxidant activity and inhibition of alpha-glucosidase by trans-resveratrol, piceid, and a novel trans-stilbene from the roots of Israeli Rumex bucephalophorus L.
    Journal of agricultural and food chemistry, 2006, Feb-22, Volume: 54, Issue:4

    Topics: Antioxidants; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Glucosides; Glycoside Hydrolase Inhibitors; Magnetic Resonance Spectroscopy; Plant Roots; Polygonaceae; Resveratrol; Stilbenes

2006
Resveratrol oligomers and their O-glucosides from Cotylelobium lanceolatum.
    Chemical & pharmaceutical bulletin, 2006, Volume: 54, Issue:3

    Topics: Ericales; Glucosides; Isomerism; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Resveratrol; Spectrometry, Mass, Fast Atom Bombardment; Spectrophotometry, Ultraviolet; Stilbenes; Structure-Activity Relationship

2006
Resveratrol and its glycon piceid are stable polyphenols.
    Journal of medicinal food, 2006,Spring, Volume: 9, Issue:1

    Topics: Chromatography, High Pressure Liquid; Dietary Supplements; Drug Stability; Flavonoids; Fruit; Glucosides; Phenols; Plant Extracts; Polyphenols; Resveratrol; Stilbenes; Time Factors; Vitis

2006
Postconditioning's protection of THSG on cardiac ischemia-reperfusion injury and mechanism.
    Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 2006, Volume: 26, Issue:1

    Topics: Animals; Antioxidants; Female; Glucosides; Ischemic Preconditioning, Myocardial; Male; Polygonum; Random Allocation; Rats; Rats, Wistar; Reperfusion Injury; Stilbenes

2006
Constitutive accumulation of cis-piceid in transgenic Arabidopsis overexpressing a sorghum stilbene synthase gene.
    Plant & cell physiology, 2006, Volume: 47, Issue:7

    Topics: Acyltransferases; Arabidopsis; DNA, Plant; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Genes, Plant; Glucosides; Isomerism; Plants, Genetically Modified; Sorghum; Stilbenes

2006
Piceid (resveratrol glucoside) synthesis in stilbene synthase transgenic apple fruit.
    Journal of agricultural and food chemistry, 2006, Jun-28, Volume: 54, Issue:13

    Topics: Acyltransferases; Fruit; Gene Expression; Glucosides; Malus; Phenols; Plants, Genetically Modified; Recombinant Proteins; RNA, Messenger; Stilbenes; Streptomyces; Vitis

2006
[Contents comparison of resveratrol and polydatin in the wild Polygonum cuspidatum plant and its tissue cultures].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2006, Volume: 31, Issue:8

    Topics: Biomass; Chromatography, High Pressure Liquid; Fallopia japonica; Glucosides; Plant Leaves; Plant Roots; Plant Stems; Plants, Medicinal; Reproducibility of Results; Resveratrol; Rhizome; Seedlings; Stilbenes; Tissue Culture Techniques

2006
Involvement of cell adhesion molecules in polydatin protection of brain tissues from ischemia-reperfusion injury.
    Brain research, 2006, Sep-19, Volume: 1110, Issue:1

    Topics: Analysis of Variance; Animals; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression; Glucosides; Immunohistochemistry; Intercellular Adhesion Molecule-1; Male; Neural Cell Adhesion Molecules; Neurologic Examination; Neuroprotective Agents; Oligonucleotide Array Sequence Analysis; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Stilbenes; Vascular Cell Adhesion Molecule-1

2006
Determination of piceid in rat plasma and tissues by high-performance liquid chromatographic method with UV detection.
    Biomedical chromatography : BMC, 2006, Volume: 20, Issue:11

    Topics: Animals; Chromatography, High Pressure Liquid; Drug Stability; Drugs, Chinese Herbal; Glucosides; Male; Rats; Rats, Wistar; Reproducibility of Results; Stilbenes; Tissue Distribution; Ultraviolet Rays

2006
[Effects of light intensity on resveratrol and polydatin production in Rumex gmelini root].
    Ying yong sheng tai xue bao = The journal of applied ecology, 2006, Volume: 17, Issue:5

    Topics: Glucosides; Plant Roots; Resveratrol; Rumex; Seasons; Stilbenes; Sunlight; Time Factors

2006
Learning-memory deficit with aging in APP transgenic mice of Alzheimer's disease and intervention by using tetrahydroxystilbene glucoside.
    Behavioural brain research, 2006, Oct-16, Volume: 173, Issue:2

    Topics: Age Factors; Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Analysis of Variance; Animals; Disease Models, Animal; Glucosides; Learning Disabilities; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Pattern Recognition, Visual; Stilbenes

2006
[Quantitative determination of the (E) - and (Z) -diastereomers of resveratrol and resveratrol glucoside in the roots of Polygonum cuspidatum by HPLC and elementary study on their fluorescence].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2006, Volume: 41, Issue:6

    Topics: Chromatography, High Pressure Liquid; Fallopia japonica; Fluorescence; Glucosides; Plant Roots; Plants, Medicinal; Reproducibility of Results; Resveratrol; Sensitivity and Specificity; Stereoisomerism; Stilbenes

2006
Transport, deglycosylation, and metabolism of trans-piceid by small intestinal epithelial cells.
    European journal of nutrition, 2006, Volume: 45, Issue:7

    Topics: beta-Glucosidase; Biological Transport; Caco-2 Cells; Chromatography, High Pressure Liquid; Epithelial Cells; Glucosides; Humans; Intestinal Absorption; Intestine, Small; Lactase-Phlorizin Hydrolase; Membrane Glycoproteins; Resveratrol; Stilbenes; Wine

2006
Desoxyrhaponticin (3,5-dihydroxy-4'-methoxystilbene 3-O-beta-D-glucoside) inhibits glucose uptake in the intestine and kidney: In vitro and in vivo studies.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 320, Issue:1

    Topics: Animals; Biological Transport; Diabetes Mellitus, Experimental; Glucose; Glucosides; Hyperglycemia; Hypoglycemia; Hypoglycemic Agents; Intestinal Mucosa; Kidney; Microvilli; Rabbits; Rats; Rats, Wistar; Stilbenes

2007
[HPLC fingerprint of Rhizoma Polygoni Cuspidati].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2006, Volume: 31, Issue:12

    Topics: Chromatography, High Pressure Liquid; Emodin; Fallopia japonica; Glucosides; Plants, Medicinal; Quality Control; Reproducibility of Results; Resveratrol; Rhizome; Stilbenes; Technology, Pharmaceutical

2006
Comparative study of chemical constituents of rhubarb from different origins.
    Chemical & pharmaceutical bulletin, 2006, Volume: 54, Issue:11

    Topics: Anthracenes; Anthraquinones; Butanones; Chromatography, High Pressure Liquid; Flavonoids; Gallic Acid; Glucosides; Hydrolyzable Tannins; Molecular Structure; Proanthocyanidins; Rheum; Sensitivity and Specificity; Species Specificity; Stereoisomerism; Stilbenes

2006
A new stilbene glucoside from the roots of Polygonum multiflorum Thunb.
    Archives of pharmacal research, 2006, Volume: 29, Issue:11

    Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Chromatography, Thin Layer; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Glucosides; Humans; Magnetic Resonance Spectroscopy; Molecular Conformation; Plant Roots; Polygonum; Spectrophotometry, Ultraviolet; Stilbenes; Tetrazolium Salts; Thiazoles; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors

2006
Four new trimeric stilbene glucosides from Welwitschia mirabilis.
    Chemistry & biodiversity, 2005, Volume: 2, Issue:6

    Topics: Glucosides; Gnetophyta; Molecular Structure; Plant Roots; Plant Stems; Stilbenes

2005
Mesocarp localization of a bi-functional resveratrol/hydroxycinnamic acid glucosyltransferase of Concord grape (Vitis labrusca).
    The Plant journal : for cell and molecular biology, 2007, Volume: 49, Issue:4

    Topics: Acyltransferases; Amino Acid Sequence; Coumaric Acids; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Glucosides; Glucosyltransferases; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Molecular Structure; Phylogeny; Recombinant Proteins; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Sequence Alignment; Stilbenes; Substrate Specificity; Vitis

2007
[Effect of preparation on the major chemical constituents of Polygonum multiflorum].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2006, Volume: 29, Issue:10

    Topics: Anthraquinones; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Emodin; Ethanol; Glucosides; Hot Temperature; Plant Tubers; Plants, Medicinal; Polygonum; Stilbenes; Technology, Pharmaceutical; Time Factors

2006
Biotransformation of piceid in Polygonum cuspidatum to resveratrol by Aspergillus oryzae.
    Applied microbiology and biotechnology, 2007, Volume: 75, Issue:4

    Topics: Aspergillus oryzae; Biomass; Biotransformation; Fallopia japonica; Fermentation; Glucosides; Hydrolysis; Molecular Structure; Resveratrol; Stilbenes; Sulfuric Acids

2007
[Blood lipid-regulation of stilbene glycoside from polygonum multiflorum].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2007, Volume: 32, Issue:4

    Topics: Animals; Anticholesteremic Agents; Atorvastatin; Cholesterol, LDL; Glucosides; Hepatocytes; Heptanoic Acids; Hydroxymethylglutaryl CoA Reductases; Hyperlipidemias; Male; Plant Tubers; Plants, Medicinal; Polygonum; Pyrroles; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, LDL; RNA, Messenger; Stilbenes; Triglycerides

2007
Simultaneous determination of trans-resveratrol-3-O-glucoside and its two metabolites in rat plasma using liquid chromatography with ultraviolet detection.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2007, Jul-01, Volume: 854, Issue:1-2

    Topics: Animals; Chromatography, Liquid; Glucosides; Rats; Rats, Wistar; Reproducibility of Results; Resveratrol; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Stilbenes

2007
Transgenic alfalfa that accumulates piceid (trans-resveratrol-3-O-beta-D-glucopyranoside) requires the presence of beta-glucosidase to inhibit the formation of aberrant crypt foci in the colon of CF-1 mice.
    Nutrition and cancer, 2007, Volume: 58, Issue:1

    Topics: Acyltransferases; Animals; beta-Glucosidase; Colonic Neoplasms; Disease Models, Animal; Female; Glucosides; Humans; Medicago sativa; Mice; Mice, Inbred Strains; Plants, Genetically Modified; Precancerous Conditions; Random Allocation; Resveratrol; Stilbenes

2007
Quantitative determination of trans-polydatin, a natural strong anti-oxidative compound, in rat plasma and cellular environment of a human colon adenocarcinoma cell line for pharmacokinetic studies.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2007, Aug-15, Volume: 855, Issue:2

    Topics: Adenocarcinoma; Animals; Antioxidants; Cell Line, Tumor; Chromatography, High Pressure Liquid; Colonic Neoplasms; Glucosides; Rats; Reproducibility of Results; Sensitivity and Specificity; Stilbenes; Time Factors

2007
Acteoside inhibits human promyelocytic HL-60 leukemia cell proliferation via inducing cell cycle arrest at G0/G1 phase and differentiation into monocyte.
    Carcinogenesis, 2007, Volume: 28, Issue:9

    Topics: Antineoplastic Agents, Phytogenic; Cell Cycle; Cell Differentiation; Cell Division; Epidermal Growth Factor; G1 Phase; Glucosides; HL-60 Cells; Humans; Muscle Cells; Phenols; Resting Phase, Cell Cycle; Resveratrol; Stilbenes; Tetradecanoylphorbol Acetate

2007
Different sorption behaviors for wine polyphenols in contact with oak wood.
    Journal of agricultural and food chemistry, 2007, Aug-22, Volume: 55, Issue:17

    Topics: Adsorption; Anthocyanins; Flavonoids; Glucosides; Kinetics; Phenols; Polyphenols; Quercus; Resveratrol; Stilbenes; Wine; Wood

2007
[Application of macroporous resin in purification for effective part from Polygonum cuspidatum].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2007, Volume: 32, Issue:11

    Topics: Adsorption; Anthraquinones; Drugs, Chinese Herbal; Emodin; Fallopia japonica; Glucosides; Plants, Medicinal; Resins, Synthetic; Resveratrol; Stilbenes; Technology, Pharmaceutical; Temperature

2007
[Metabolism of trans-resveratrol-3-O-glucoside in vitro in rat tissues].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2007, Volume: 42, Issue:5

    Topics: Animals; Duodenum; Female; Gastric Mucosa; Glucosides; Ileum; Intestinal Mucosa; Intestine, Small; Jejunum; Liver; Male; Rats; Rats, Wistar; Resveratrol; Stilbenes

2007
Occurrence of resveratrol and piceid in American and European hop cones.
    Journal of agricultural and food chemistry, 2007, Oct-17, Volume: 55, Issue:21

    Topics: Chromatography, High Pressure Liquid; Europe; Glucosides; Humulus; Mass Spectrometry; Resveratrol; Species Specificity; Stilbenes; Time Factors; United States

2007
Changes in hippocampal synapses and learning-memory abilities in age-increasing rats and effects of tetrahydroxystilbene glucoside in aged rats.
    Neuroscience, 2007, Nov-23, Volume: 149, Issue:4

    Topics: Age Factors; Aging; Analysis of Variance; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation, Developmental; Glucosides; Hippocampus; Learning; Male; Maze Learning; Microscopy, Electron, Transmission; Rats; Rats, Sprague-Dawley; Stilbenes; Synapses; Synaptophysin; Time Factors

2007
Protective effects of 2,3,5,4'-tetrahydroxystilbene-2-O-beta-d-glucoside, an active component of Polygonum multiflorum Thunb, on experimental colitis in mice.
    European journal of pharmacology, 2008, Jan-14, Volume: 578, Issue:2-3

    Topics: Acetic Acid; Acute Disease; Animals; Anti-Inflammatory Agents; Antioxidants; Chronic Disease; Colitis; Colon; Disease Models, Animal; Dose-Response Relationship, Drug; Gastrointestinal Agents; Glucosides; Malondialdehyde; Mesalamine; Mice; Mitomycin; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Peroxidase; Polygonum; Stilbenes; Superoxide Dismutase; Time Factors

2008
Accumulation of trans-piceid in sorghum seedlings infected with Colletotrichum sublineolum.
    Phytochemistry, 2008, Volume: 69, Issue:3

    Topics: Colletotrichum; Glucosides; Glycosylation; Molecular Structure; Seedlings; Sorghum; Stereoisomerism; Stilbenes

2008
2,3,4',5-Tetrahydroxystilbene-2-O-beta-D-glucoside suppresses matrix metalloproteinase expression and inflammation in atherosclerotic rats.
    Clinical and experimental pharmacology & physiology, 2008, Volume: 35, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Atherosclerosis; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Glucosides; Inflammation; Male; Matrix Metalloproteinases; Rats; Rats, Sprague-Dawley; Simvastatin; Stilbenes

2008
[Biological dressing with human hair keratin-collagen sponge-poly 2-hydroxyethyl methacrylate composite promotes burn wound healing in SD rats].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2007, Volume: 27, Issue:11

    Topics: Animals; Biological Dressings; Burns; Cattle; Collagen; Drug Delivery Systems; Drugs, Chinese Herbal; Glucosides; Humans; Keratins; Polyhydroxyethyl Methacrylate; Rats; Rats, Sprague-Dawley; Stilbenes; Swine; Tissue Engineering; Wound Healing

2007
Diastereomeric stilbene glucoside dimers from the bark of Norway spruce (Picea abies).
    Phytochemistry, 2008, Volume: 69, Issue:3

    Topics: Cellulase; Computer Simulation; Dimerization; Glucosides; Hydrolysis; Magnetic Resonance Spectroscopy; Molecular Conformation; Norway; Picea; Plant Bark; Reference Standards; Stereoisomerism; Stilbenes

2008
[Increasing the content of active constituents in Polygonum cuspidatum hairy root by gene transformation technology].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2007, Volume: 42, Issue:9

    Topics: Acyltransferases; DNA Primers; DNA, Plant; Drugs, Chinese Herbal; Fallopia japonica; Genetic Vectors; Glucosides; Molecular Sequence Data; Plant Roots; Plants, Genetically Modified; Plants, Medicinal; Resveratrol; Rhizobium; Stilbenes; Transformation, Genetic

2007
Isocratic chromatography of resveratrol and piceid after previous generation of fluorescent photoproducts: wine analysis without sample preparation.
    Journal of separation science, 2007, Volume: 30, Issue:18

    Topics: Chromatography, Liquid; Fluorescent Dyes; Glucosides; Isomerism; Molecular Structure; Resveratrol; Stilbenes; Surface Properties; Wine

2007
Optimization and validation of a chromatographic method for the simultaneous quantification of six bioactive compounds in Rhizoma et Radix Polygoni Cuspidati.
    The Journal of pharmacy and pharmacology, 2008, Volume: 60, Issue:1

    Topics: Anthraquinones; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Emodin; Fallopia japonica; Glucosides; Molecular Structure; Reproducibility of Results; Resveratrol; Rhizome; Stilbenes; Technology, Pharmaceutical

2008
Concentrations of resveratrol and derivatives in foods and estimation of dietary intake in a Spanish population: European Prospective Investigation into Cancer and Nutrition (EPIC)-Spain cohort.
    The British journal of nutrition, 2008, Volume: 100, Issue:1

    Topics: Adult; Age Factors; Aged; Cohort Studies; Databases, Factual; Diet, Mediterranean; Feeding Behavior; Female; Food Analysis; Glucosides; Humans; Male; Middle Aged; Resveratrol; Sex Factors; Spain; Stilbenes; Wine

2008
[Study on correlation of soil nutrients and content of active constituents in root of Rumex gmelini].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2007, Volume: 32, Issue:19

    Topics: Anthraquinones; Ecosystem; Emodin; Fertilizers; Glucosides; Nitrogen; Phosphorus; Plant Roots; Plants, Medicinal; Potassium; Regression Analysis; Resveratrol; Rumex; Soil; Stilbenes

2007
Fate of resveratrol and piceid through different hop processings and storage times.
    Journal of agricultural and food chemistry, 2008, Jan-23, Volume: 56, Issue:2

    Topics: Chromatography, High Pressure Liquid; Drug Stability; Food Handling; Glucosides; Humulus; Resveratrol; Stilbenes; Tandem Mass Spectrometry

2008
A potent tyrosinase activator from Radix Polygoni multiflori and its melanogenesis stimulatory effect in B16 melanoma cells.
    Phytotherapy research : PTR, 2008, Volume: 22, Issue:5

    Topics: Animals; Anthraquinones; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Enzyme Activation; Glucosides; Melanins; Melanoma, Experimental; Mice; Monophenol Monooxygenase; Plant Extracts; Polygonum; Stilbenes

2008
Antioxidant properties of resveratrol and piceid on lipid peroxidation in micelles and monolamellar liposomes.
    Biophysical chemistry, 2008, Volume: 135, Issue:1-3

    Topics: Antioxidants; Butylated Hydroxytoluene; Glucosides; Lipid Peroxidation; Micelles; Models, Biological; Molecular Structure; Resveratrol; Stilbenes; Unilamellar Liposomes; Vitamin E

2008
[Comparison of content of 2,3,5,4'-tetrahydroxystilbene-2-O-beta-D-glucoside and anthraquinon in different ploidy Radix Polygoni Multiflori].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2007, Volume: 30, Issue:12

    Topics: Anthraquinones; Chromatography, High Pressure Liquid; Emodin; Glucosides; Plant Roots; Plants, Medicinal; Ploidies; Polygonum; Reproducibility of Results; Stilbenes

2007
Protective effect of polydatin against ischemia/reperfusion injury in rat heart.
    Sheng li xue bao : [Acta physiologica Sinica], 2008, Apr-25, Volume: 60, Issue:2

    Topics: Animals; Glucosides; Heart; Malondialdehyde; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Stilbenes; Superoxide Dismutase

2008
Influence of pressing method on juice stilbene content in muscadine and bunch grapes.
    Journal of food science, 2008, Volume: 73, Issue:4

    Topics: Beverages; Cold Temperature; Food Handling; Freezing; Fruit; Glucosides; Hot Temperature; Polygalacturonase; Resveratrol; Stilbenes; Vitis

2008
Study of vacuum microwave-assisted extraction of polyphenolic compounds and pigment from Chinese herbs.
    Journal of chromatography. A, 2008, Jul-11, Volume: 1198-1199

    Topics: Chemical Fractionation; Coloring Agents; Coumaric Acids; Drugs, Chinese Herbal; Emodin; Flavonoids; Glucosides; Microwaves; Myrica; Phenols; Plant Leaves; Polyphenols; Quercetin; Reproducibility of Results; Resveratrol; Stilbenes; Vacuum

2008
Principal components of phenolics to characterize red Vinho Verde grapes: anthocyanins or non-coloured compounds?
    Talanta, 2008, Jun-15, Volume: 75, Issue:5

    Topics: Anthocyanins; Catechin; Flavonoids; Flavonols; Glucosides; Hydroxybenzoates; Phenols; Pigments, Biological; Quercetin; Stilbenes; Vitis

2008
[Effects of 2, 3, 4', 5-tetrahydroxystilbene -2-O-beta-D glucoside on content of nitric oxide synthase and expression of nitric oxide synthase in artery vessels of experimental atherosclerotic rats].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2008, Volume: 33, Issue:8

    Topics: Animals; Arteries; Atherosclerosis; Gene Expression Regulation, Enzymologic; Glucosides; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Rats; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes

2008
Analysis of selected stilbenes in Polygonum cuspidatum by HPLC coupled with CoulArray detection.
    Journal of separation science, 2008, Volume: 31, Issue:13

    Topics: Chromatography, High Pressure Liquid; Electrochemistry; Fallopia japonica; Glucosides; Hydrogen-Ion Concentration; Plant Roots; Resveratrol; Stilbenes

2008
Effects of polydatin from Polygonum cuspidatum on lipid profile in hyperlipidemic rabbits.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2009, Volume: 63, Issue:7

    Topics: Animals; Body Weight; Cholesterol, Dietary; Cholesterol, HDL; Cholesterol, LDL; Fallopia japonica; Glucosides; Hyperlipidemias; Hypolipidemic Agents; Male; Phytotherapy; Plant Extracts; Plant Roots; Rabbits; Stilbenes; Triglycerides

2009
Microwave-assisted aqueous two-phase extraction of piceid, resveratrol and emodin from Polygonum cuspidatum by ethanol/ammonium sulphate systems.
    Biotechnology letters, 2008, Volume: 30, Issue:12

    Topics: Acetonitriles; Ammonium Sulfate; Chromatography, High Pressure Liquid; Emodin; Ethanol; Fallopia japonica; Glucosides; Microwaves; Plant Extracts; Resveratrol; Stilbenes

2008
Survey of the trans-resveratrol and trans-piceid content of cocoa-containing and chocolate products.
    Journal of agricultural and food chemistry, 2008, Sep-24, Volume: 56, Issue:18

    Topics: Beverages; Cacao; Carbohydrates; Diet; Fruit; Glucosides; Powders; Resveratrol; Stilbenes; Vitis; Wine

2008
[Studies on chemical constituents of rhizome of Matteuccia struthiopteris].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2008, Volume: 33, Issue:14

    Topics: Chromones; Dryopteridaceae; Flavonoids; Glucosides; Magnetic Resonance Spectroscopy; Rhizome; Stilbenes

2008
Targeted isolation and structure elucidation of stilbene glycosides from the bark of Lysidice brevicalyx Wei guided by biological and chemical screening.
    Journal of natural products, 2008, Volume: 71, Issue:11

    Topics: Antioxidants; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Fabaceae; Glucosides; Glycosides; Molecular Structure; Plant Bark; Resveratrol; Stilbenes

2008
Direct determination of polydatin and its metabolite in rat excrement samples by high-performance liquid chromatography.
    Chemical & pharmaceutical bulletin, 2008, Volume: 56, Issue:11

    Topics: Animals; Calibration; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Feces; Gastrointestinal Tract; Glucosides; Indicators and Reagents; Mass Spectrometry; Rats; Rats, Wistar; Reproducibility of Results; Resveratrol; Spectrophotometry, Ultraviolet; Stilbenes

2008
The polyphenol piceid destabilizes preformed amyloid fibrils and oligomers in vitro: hypothesis on possible molecular mechanisms.
    Neurochemical research, 2009, Volume: 34, Issue:6

    Topics: Amyloid; Amyloid beta-Peptides; Benzothiazoles; Chromatography, Gel; Flavonoids; Fluorescent Dyes; Glucosides; Humans; Microscopy, Electron; Oligopeptides; Peptide Fragments; Phenols; Polyphenols; Protein Structure, Secondary; Spectrometry, Fluorescence; Stilbenes; Thiazoles

2009
Lipid-lowering effects of polydatin from Polygonum cuspidatum in hyperlipidemic hamsters.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2009, Volume: 16, Issue:6-7

    Topics: Animals; Body Weight; Cholesterol, HDL; Cholesterol, LDL; Cricetinae; Fallopia japonica; Glucosides; Hyperlipidemias; Hypolipidemic Agents; Male; Mesocricetus; Stilbenes; Triglycerides

2009
Functional characterization of a stilbene synthase gene using a transient expression system in planta.
    Plant cell reports, 2009, Volume: 28, Issue:4

    Topics: Acyltransferases; Arachis; Cloning, Molecular; Gene Expression Regulation, Plant; Genes, Plant; Glucosides; Nicotiana; Plant Proteins; Plants, Genetically Modified; RNA, Messenger; RNA, Plant; Stilbenes

2009
[Studies on chemical constituents from leaves of Lysidice brevicalyx].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2008, Volume: 33, Issue:22

    Topics: Chromatography, High Pressure Liquid; Fabaceae; Gallic Acid; Glucosides; Glycosides; Monosaccharides; Plant Extracts; Plant Leaves; Quercetin; Stilbenes

2008
[Harmful elements removal from Polygonum multiflorum by supercritical CO2 extraction].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2008, Volume: 31, Issue:10

    Topics: Arsenic; Carbon Dioxide; Chromatography, Supercritical Fluid; Copper; Drugs, Chinese Herbal; Glucosides; Lead; Plants, Medicinal; Polygonaceae; Pressure; Stilbenes; Technology, Pharmaceutical; Temperature

2008
Protection by tetrahydroxystilbene glucoside against cerebral ischemia: involvement of JNK, SIRT1, and NF-kappaB pathways and inhibition of intracellular ROS/RNS generation.
    Free radical biology & medicine, 2009, Aug-01, Volume: 47, Issue:3

    Topics: Animals; Antioxidants; Apoptosis; Brain; Cells, Cultured; Cytoprotection; Down-Regulation; Drugs, Chinese Herbal; Glucosides; Infarction, Middle Cerebral Artery; MAP Kinase Kinase 4; Membrane Potential, Mitochondrial; Mitochondria; NF-kappa B; Nitric Oxide Synthase Type II; Polygonum; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Reactive Nitrogen Species; Reactive Oxygen Species; Rhizome; Signal Transduction; Sirtuin 1; Stilbenes

2009
Effects of 2,3,4',5-tetrahydroxystilbene 2-O-beta-D-glucoside on vascular endothelial dysfunction in atherogenic-diet rats.
    Planta medica, 2009, Volume: 75, Issue:11

    Topics: Animals; Aorta; Atherosclerosis; Disease Models, Animal; Drugs, Chinese Herbal; Endothelium, Vascular; Glucosides; Male; Microscopy, Electron, Transmission; Nitrates; Nitric Oxide Synthase; Nitrites; Polygonum; Rats; Rats, Sprague-Dawley; RNA, Messenger; Stilbenes

2009
Stilbene glycosides are natural product inhibitors of FGF-2-induced angiogenesis.
    BMC cell biology, 2009, Apr-23, Volume: 10

    Topics: Angiogenesis Inhibitors; Animals; Burseraceae; Cattle; Cell Line; Cell Movement; Down-Regulation; Fibroblast Growth Factor 2; Glucosides; Glycosides; Humans; Inhibitory Concentration 50; Mitogen-Activated Protein Kinase 3; Receptor, Fibroblast Growth Factor, Type 1; Receptor, Fibroblast Growth Factor, Type 2; Stilbenes

2009
Dose-dependent absorption and metabolism of trans-polydatin in rats.
    Journal of agricultural and food chemistry, 2009, Jun-10, Volume: 57, Issue:11

    Topics: Animals; Dose-Response Relationship, Drug; Glucosides; Intestinal Absorption; Intestine, Small; Liver; Rats; Rats, Sprague-Dawley; Stilbenes

2009
2, 3, 5, 4'-tetrahydroxystilbene-2-O-beta-D-glucoside (THSG) induces melanogenesis in B16 cells by MAP kinase activation and tyrosinase upregulation.
    Life sciences, 2009, Aug-26, Volume: 85, Issue:9-10

    Topics: Animals; Antioxidants; Cell Line, Tumor; Enzyme Activation; Glucosides; Hair Color; Melanins; Melanoma, Experimental; Mice; Monophenol Monooxygenase; p38 Mitogen-Activated Protein Kinases; Skin Pigmentation; Stilbenes; Up-Regulation

2009
Implication of signaling pathways involving calcium, phosphorylation and active oxygen species in methyl jasmonate-induced defense responses in grapevine cell cultures.
    Journal of plant physiology, 2009, Nov-15, Volume: 166, Issue:17

    Topics: Acetates; Calcium; Cantharidin; Cells, Cultured; Cyclopentanes; Dicarboxylic Acids; Enzyme Inhibitors; Glucosides; NADPH Oxidases; Oxylipins; Phosphoric Monoester Hydrolases; Phosphorylation; Plant Growth Regulators; Plant Proteins; Reactive Oxygen Species; Resveratrol; RNA, Plant; Signal Transduction; Stilbenes; Superoxide Dismutase; Vitis

2009
Rapid separation of three glucosylated resveratrol analogues from the invasive plant Polygonum cuspidatum by high-speed countercurrent chromatography.
    Journal of separation science, 2009, Volume: 32, Issue:17

    Topics: Countercurrent Distribution; Fallopia japonica; Glucosides; Molecular Structure; Plant Extracts; Resveratrol; Solvents; Stilbenes

2009
Effect of ultraviolet doses in combined ultraviolet-ultrasound treatments on trans-resveratrol and trans-piceid contents in sliced peanut kernels.
    Journal of agricultural and food chemistry, 2009, Sep-09, Volume: 57, Issue:17

    Topics: Arachis; Chromatography, High Pressure Liquid; Dose-Response Relationship, Radiation; Drugs, Chinese Herbal; Glucosides; Resveratrol; Seeds; Stilbenes; Ultrasonics; Ultraviolet Rays

2009
Drug-protein-binding determination of stilbene glucoside using cloud-point extraction and comparison with ultrafiltration and equilibrium dialysis.
    Drug development and industrial pharmacy, 2010, Volume: 36, Issue:3

    Topics: Algorithms; Analytic Sample Preparation Methods; Antioxidants; Blood Proteins; Chromatography, High Pressure Liquid; Dialysis; Drug Stability; Freezing; Glucosides; Humans; Orosomucoid; Osmolar Concentration; Protein Binding; Serum Albumin, Bovine; Stilbenes; Surface-Active Agents; Temperature; Ultrafiltration

2010
Polydatin attenuates ischemia/reperfusion-induced apoptosis in myocardium of the rat.
    Sheng li xue bao : [Acta physiologica Sinica], 2009, Aug-25, Volume: 61, Issue:4

    Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Glucosides; In Vitro Techniques; Male; Myocardial Reperfusion Injury; Myocardium; Myocytes, Cardiac; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Stilbenes

2009
[Pharmacokinetic study of polydatin in Beagle dogs].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2009, Volume: 29, Issue:8

    Topics: Animals; Chromatography, High Pressure Liquid; Dogs; Female; Glucosides; Limit of Detection; Linear Models; Male; Reproducibility of Results; Stilbenes

2009
Phytochemical profiles of different mulberry (Morus sp.) species from China.
    Journal of agricultural and food chemistry, 2009, Oct-14, Volume: 57, Issue:19

    Topics: 1-Deoxynojirimycin; Anthocyanins; Beverages; China; Chromatography, High Pressure Liquid; Flavonoids; Fruit; Glucosides; Morus; Plant Leaves; Resveratrol; Rutin; Species Specificity; Stilbenes

2009
Soluble polyphenols: synthesis and bioavailability of 3,4',5-tri(alpha-D-glucose-3-O-succinyl) resveratrol.
    Bioorganic & medicinal chemistry letters, 2009, Dec-01, Volume: 19, Issue:23

    Topics: Animals; Biological Availability; Flavonoids; Glucosides; Molecular Structure; Phenols; Polyphenols; Rats; Solubility; Stilbenes; Time Factors

2009
Protective effect of tetrahydroxystilbene glucoside on cardiotoxicity induced by doxorubicin in vitro and in vivo.
    Acta pharmacologica Sinica, 2009, Volume: 30, Issue:11

    Topics: Animals; Animals, Newborn; Antibiotics, Antineoplastic; Apoptosis; Calcium; Cardiotonic Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Doxorubicin; Glucosides; Heart Diseases; Male; Mice; Myocytes, Cardiac; Rats; Reactive Oxygen Species; Signal Transduction; Stilbenes

2009
Tetrahydroxy stilbene glucoside reduces the cognitive impairment and overexpression of amyloid precursor protein induced by aluminum exposure.
    Neuroscience bulletin, 2009, Volume: 25, Issue:6

    Topics: Aluminum Chloride; Aluminum Compounds; Amyloid beta-Protein Precursor; Animals; Avoidance Learning; Blotting, Western; Chlorides; Cognition Disorders; Glucosides; Hippocampus; Male; Neuroprotective Agents; Neuropsychological Tests; Random Allocation; Rats; Rats, Sprague-Dawley; Stilbenes; Time Factors; Vitamin E; Vitamins

2009
[Identification and determination of major constituents in Polygonum cuspidatum Sieb. et Zucc. by high performance liquid chromatography/electrospray ionization-ion trap-time-of-flight mass spectrometry].
    Se pu = Chinese journal of chromatography, 2009, Volume: 27, Issue:4

    Topics: Anthraquinones; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Fallopia japonica; Glucosides; Spectrometry, Mass, Electrospray Ionization; Stilbenes

2009
Preformulation stability of trans-resveratrol and trans-resveratrol glucoside (Piceid).
    Journal of agricultural and food chemistry, 2010, Feb-10, Volume: 58, Issue:3

    Topics: Chromatography, High Pressure Liquid; Drug Stability; Fallopia japonica; Glucosides; Plant Extracts; Resveratrol; Stilbenes; Temperature

2010
Hypotensive resuscitation combined with polydatin improve microcirculation and survival in a rabbit model of uncontrolled hemorrhagic shock in pregnancy.
    The Journal of surgical research, 2011, Jun-01, Volume: 168, Issue:1

    Topics: Animals; Blood Gas Analysis; Blood Pressure; Combined Modality Therapy; Drugs, Chinese Herbal; Female; Glucosides; Hematocrit; Hypotension; Microcirculation; Models, Animal; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy, Animal; Rabbits; Resuscitation; Shock, Hemorrhagic; Stilbenes; Survival Rate

2011
Cre-mediated seed-specific transgene excision in tobacco.
    Plant molecular biology, 2010, Volume: 72, Issue:6

    Topics: 2S Albumins, Plant; Brassica napus; Genetic Engineering; Germination; Glucosides; Integrases; Nicotiana; Plants, Genetically Modified; Promoter Regions, Genetic; Recombination, Genetic; Resveratrol; Seeds; Stilbenes; Transgenes

2010
Stilbene glucoside from Polygonum multiflorum Thunb.: a novel natural inhibitor of advanced glycation end product formation by trapping of methylglyoxal.
    Journal of agricultural and food chemistry, 2010, Feb-24, Volume: 58, Issue:4

    Topics: Chromatography, Liquid; Diabetes Complications; Diabetes Mellitus; Glucosides; Glycation End Products, Advanced; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Models, Molecular; Molecular Conformation; Polygonum; Pyruvaldehyde; Resveratrol; Stilbenes

2010
Effect of palmitoylethanolamide-polydatin combination on chronic pelvic pain associated with endometriosis: preliminary observations.
    European journal of obstetrics, gynecology, and reproductive biology, 2010, Volume: 150, Issue:1

    Topics: Adult; Amides; Drug Combinations; Dyspareunia; Endocannabinoids; Endometriosis; Ethanolamines; Female; Glucosides; Humans; Mast Cells; Middle Aged; Palmitic Acids; Pelvic Pain; Stilbenes

2010
Gneyulins A and B, stilbene trimers, and noidesols A and B, dihydroflavonol-C-glucosides, from the bark of Gnetum gnemonoides.
    Journal of natural products, 2010, Apr-23, Volume: 73, Issue:4

    Topics: Crystallography, X-Ray; Flavonols; Glucosides; Gnetum; Malaysia; Molecular Conformation; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plant Bark; Sodium-Glucose Transporter 1; Sodium-Glucose Transporter 2 Inhibitors; Stilbenes

2010
Quantitative structure-antioxidant activity relationship of trans-resveratrol oligomers, trans-4,4'-dihydroxystilbene dimer, trans-resveratrol-3-O-glucuronide, glucosides: trans-piceid, cis-piceid, trans-astringin and trans-resveratrol-4'-O-beta-D-glucopy
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:6

    Topics: Dimerization; Free Radical Scavengers; Glucose; Glucosides; Glucuronides; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship; Quantum Theory; Resveratrol; Stereoisomerism; Stilbenes

2010
Evolution of resveratrol and piceid contents during the industrial winemaking process of sherry wine.
    Journal of agricultural and food chemistry, 2010, Apr-14, Volume: 58, Issue:7

    Topics: Fermentation; Food Industry; Glucosides; Industrial Microbiology; Resveratrol; Stilbenes; Vitis; Wine

2010
Resveratrol from transgenic alfalfa for prevention of aberrant crypt foci in mice.
    Nutrition and cancer, 2010, Volume: 62, Issue:3

    Topics: Animals; Azoxymethane; Body Weight; Chromatography, High Pressure Liquid; Colonic Neoplasms; Eating; Female; Glucosides; Lactase-Phlorizin Hydrolase; Medicago sativa; Mice; Plants, Genetically Modified; Precancerous Conditions; Resveratrol; Stilbenes

2010
Bioactivity-guided separation of anti-acidogenic substances against Streptococcus mutans UA 159 from Polygonum cuspidatum.
    Oral diseases, 2010, Volume: 16, Issue:2

    Topics: Acids; Anthracenes; Cariostatic Agents; Chelating Agents; Chemical Fractionation; Chromatography, Gel; Chromatography, High Pressure Liquid; Chromatography, Liquid; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Emodin; Fallopia japonica; Glucosides; Glycolysis; Glycosides; Humans; Hydrogen-Ion Concentration; Materials Testing; Phenols; Plant Extracts; Resveratrol; Sodium Fluoride; Stilbenes; Streptococcus mutans

2010
[Neuroprotective mechanism of tetrahydroxystilbene glucoside on rats after cerebral ischemia-reperfusion].
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2010, Volume: 35, Issue:4

    Topics: Animals; GAP-43 Protein; Glucosides; Infarction, Middle Cerebral Artery; Male; Nerve Growth Factor; Neuroprotective Agents; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Stilbenes

2010
[Protective effect of polydatin on a PC12 cell model of oxygen-glucose deprivation].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2010, Volume: 30, Issue:5

    Topics: Animals; Brain Ischemia; Cell Survival; Glucose; Glucosides; L-Lactate Dehydrogenase; Malondialdehyde; Nitric Oxide; Oxygen; PC12 Cells; Protective Agents; Rats; Stilbenes; Superoxide Dismutase

2010
Piceatannol-3'-O-beta-D-glucopyranoside as an active component of rhubarb activates endothelial nitric oxide synthase through inhibition of arginase activity.
    Experimental & molecular medicine, 2010, Jul-31, Volume: 42, Issue:7

    Topics: Animals; Aorta; Arginase; Dose-Response Relationship, Drug; Endothelial Cells; Enzyme Activation; Glucosides; Humans; Mice; Mice, Inbred C57BL; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrites; Reactive Oxygen Species; Rheum; Stilbenes

2010
Effects of polydatin on attenuating ventricular remodeling in isoproterenol-induced mouse and pressure-overload rat models.
    Fitoterapia, 2010, Volume: 81, Issue:7

    Topics: Aldosterone; Angiotensin II; Animals; Aorta, Abdominal; Blood Pressure; Cardiovascular Agents; Collagen; Cyclic AMP; Drugs, Chinese Herbal; Endothelin-1; Fallopia japonica; Glucosides; Heart; Hypertrophy, Left Ventricular; Isoproterenol; Male; Mice; Myocytes, Cardiac; Organ Size; Phytotherapy; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Stilbenes; Tumor Necrosis Factor-alpha; Ventricular Remodeling

2010
Tetrahydroxystilbene glucoside attenuates MPP+-induced apoptosis in PC12 cells by inhibiting ROS generation and modulating JNK activation.
    Neuroscience letters, 2010, Oct-08, Volume: 483, Issue:1

    Topics: 1-Methyl-4-phenylpyridinium; Analysis of Variance; Animals; Apoptosis; Blotting, Western; Cell Count; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Flow Cytometry; Glucosides; PC12 Cells; Rats; Reactive Oxygen Species; Stilbenes

2010
[Determination of 2,3,5,4'-tetrahydroxystilbene-2-O-beta-D-glucopyranoside and anthraquinon simultaneously in Polygonum multiflori of different growing stage and gathering periods by HPLC].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2010, Volume: 35, Issue:10

    Topics: Anthraquinones; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Glucosides; Polygonum; Stilbenes

2010
Inhibition of TNF-α-mediated endothelial cell-monocyte cell adhesion and adhesion molecules expression by the resveratrol derivative, trans-3,5,4'-trimethoxystilbene.
    Phytotherapy research : PTR, 2011, Volume: 25, Issue:3

    Topics: Cell Adhesion; Cell Line, Tumor; Endothelial Cells; Glucosides; Humans; Intercellular Adhesion Molecule-1; Molecular Structure; Monocytes; NF-kappa B; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha; Umbilical Veins; Vascular Cell Adhesion Molecule-1

2011
Tetrahydroxystilbene glucoside ameliorates diabetic nephropathy in rats: involvement of SIRT1 and TGF-β1 pathway.
    European journal of pharmacology, 2010, Dec-15, Volume: 649, Issue:1-3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Biomarkers; Cell Line; Cyclooxygenase 2; Diabetic Nephropathies; Dose-Response Relationship, Drug; Glucosides; Histone Deacetylase Inhibitors; Hyperglycemia; Kidney Cortex; Male; Mesangial Cells; Oxidative Stress; Random Allocation; Rats; Rats, Sprague-Dawley; Signal Transduction; Sirtuin 1; Stilbenes; Transforming Growth Factor beta1

2010
Preventive oral treatment with resveratrol pro-prodrugs drastically reduce colon inflammation in rodents.
    Journal of medicinal chemistry, 2010, Oct-28, Volume: 53, Issue:20

    Topics: Acute-Phase Proteins; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Colitis; Colon; Cytokines; Dextran Sulfate; Diarrhea; Dinoprostone; Feces; Gastrointestinal Transit; Glucosides; Humans; Intestinal Absorption; Intestinal Mucosa; Mice; Mice, Inbred C57BL; Peroxidase; Prodrugs; Resveratrol; Stereoisomerism; Stilbenes; Structure-Activity Relationship

2010
Sensitized synchronous fluorimetric determination of trans-resveratrol and trans-piceid in red wine based on their immobilization on nylon membranes.
    Talanta, 2010, Oct-15, Volume: 82, Issue:5

    Topics: Equipment Design; Glucosides; Indicators and Reagents; Membranes, Artificial; Nylons; Resveratrol; Solutions; Spectrometry, Fluorescence; Stereoisomerism; Stilbenes; Wine

2010
Chemical constituents in the leaves of Vateria indica.
    Chemical & pharmaceutical bulletin, 2010, Volume: 58, Issue:10

    Topics: Circular Dichroism; Dimerization; Dipterocarpaceae; Glucosides; Magnetic Resonance Spectroscopy; Molecular Conformation; Plant Leaves; Resveratrol; Stilbenes

2010
Inhibition of melanogenesis by piceid isolated from Polygonum cuspidatum.
    Archives of pharmacal research, 2010, Volume: 33, Issue:9

    Topics: Animals; Cell Line; Cell Proliferation; Down-Regulation; Fallopia japonica; Glucosides; Hyperpigmentation; Intramolecular Oxidoreductases; Magnetic Resonance Spectroscopy; Melanins; Melanocytes; Membrane Glycoproteins; Mice; Microphthalmia-Associated Transcription Factor; Molecular Structure; Monophenol Monooxygenase; Osmolar Concentration; Oxidoreductases; Plant Roots; RNA, Messenger; Spectrometry, Mass, Fast Atom Bombardment; Stilbenes

2010
Histochemical analysis of the root tuber of Polygonum multiflorum Thunb. (Fam. Polygonaceae).
    Microscopy research and technique, 2011, Volume: 74, Issue:6

    Topics: Anthraquinones; Chromatography, High Pressure Liquid; Glucosides; Histocytochemistry; Mass Spectrometry; Microscopy, Fluorescence; Polygonum; Root Nodules, Plant; Stilbenes

2011
Tetrahydroxystilbene glucoside, a plant-derived cognitive enhancer, promotes hippocampal synaptic plasticity.
    European journal of pharmacology, 2011, Jan-10, Volume: 650, Issue:1

    Topics: Animals; CA1 Region, Hippocampal; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Differentiation; Cognition; Electric Stimulation; Enzyme Activation; Female; Glucosides; Hippocampus; In Vitro Techniques; Intracellular Space; Long-Term Potentiation; Male; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neuronal Plasticity; Neurons; PC12 Cells; Phosphorylation; Polygonum; Rats; Stilbenes; Synapses

2011
Automatic optosensing device based on photo-induced fluorescence for determination of piceid in cocoa-containing products.
    Analytical and bioanalytical chemistry, 2011, Volume: 399, Issue:2

    Topics: Cacao; Equipment Design; Flow Injection Analysis; Glucosides; Limit of Detection; Photochemical Processes; Plants, Medicinal; Radiation; Spectrometry, Fluorescence; Stilbenes; Ultraviolet Rays

2011
Polydatin ameliorates DSS-induced colitis in mice through inhibition of nuclear factor-kappaB activation.
    Planta medica, 2011, Volume: 77, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Colitis, Ulcerative; Dextran Sulfate; Disease Models, Animal; Glucosides; Inflammation Mediators; Interleukin-1beta; Interleukin-6; Male; Mice; Mice, Inbred BALB C; NF-kappa B; Peroxidase; Pilot Projects; Resveratrol; RNA, Messenger; Signal Transduction; Stilbenes; Tumor Necrosis Factor-alpha

2011
Investigation of piceid metabolites in rat by liquid chromatography tandem mass spectrometry.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2011, Jan-01, Volume: 879, Issue:1

    Topics: Animals; Chromatography, High Pressure Liquid; Fermentation; Glucosides; Intestines; Male; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Tandem Mass Spectrometry

2011
[Studies on the chemical constituents of radix Boehmeriae].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2010, Volume: 33, Issue:7

    Topics: Boehmeria; Catechin; Chromatography; Emodin; Glucosides; Magnetic Resonance Spectroscopy; Nitrates; Plant Roots; Potassium Compounds; Stilbenes

2010
[Effects of tetrahydroxystilbene glucoside on nerve growth factor and growth associated protein in rats after cerebral ischemia-reperfusion].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2010, Volume: 33, Issue:7

    Topics: Animals; Brain Ischemia; Cerebral Cortex; Disease Models, Animal; GAP-43 Protein; Glucosides; Immunohistochemistry; Infarction, Middle Cerebral Artery; Male; Nerve Growth Factor; Neuroprotective Agents; Polygonaceae; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Stilbenes

2010
[Protective effects of polydatin against lung ischemia/reperfusion injury and the initial exploration for its mechanism].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2008, Volume: 24, Issue:1

    Topics: Animals; Female; Glucosides; Lung; Male; Protective Agents; Protein Kinase C; Rabbits; Random Allocation; Reperfusion Injury; Stilbenes

2008
[The regulative effects of polydatin on toll-like receptor 4 signal transduction pathway in lung ischemia/reperfusion injury in rabbits].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2009, Volume: 25, Issue:1

    Topics: Animals; Female; Glucosides; Intercellular Adhesion Molecule-1; Ischemia; Lung; Male; Protective Agents; Rabbits; Reperfusion Injury; RNA, Messenger; Signal Transduction; Stilbenes; Toll-Like Receptor 4; Transcription Factor RelA

2009
[The expression of matrix metalloproteinase-2,9 on atherosclerosis in experimental rats by treatment of 2,3,4',5-tetrahydroxystilbene -2-0-beta-D glucoside].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2009, Volume: 25, Issue:1

    Topics: Animals; Atherosclerosis; C-Reactive Protein; Glucosides; Interferon-alpha; Interleukin-6; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Polygonum; Rats; Rats, Sprague-Dawley; RNA, Messenger; Stilbenes

2009
Different effect of two synthetic coumarin-stilbene hybrid compounds on phagocyte activity.
    Neuro endocrinology letters, 2010, Volume: 31 Suppl 2

    Topics: Adult; Animals; Cell Line; Coumarins; Humans; Lipopolysaccharides; Macrophages; Male; Mice; Middle Aged; Models, Animal; Neutrophils; Nitric Oxide; Phagocytosis; Reactive Oxygen Species; Stilbenes; Tetradecanoylphorbol Acetate; Zymosan

2010
Determination of resveratrol and piceid in beer matrices by solid-phase extraction and liquid chromatography-tandem mass spectrometry.
    Journal of chromatography. A, 2011, Feb-04, Volume: 1218, Issue:5

    Topics: Beer; Chromatography, Liquid; Glucosides; Least-Squares Analysis; Reproducibility of Results; Resveratrol; Sensitivity and Specificity; Solid Phase Extraction; Stereoisomerism; Stilbenes; Tandem Mass Spectrometry

2011
Protection by tetrahydroxystilbene glucoside against neurotoxicity induced by MPP+: the involvement of PI3K/Akt pathway activation.
    Toxicology letters, 2011, Apr-10, Volume: 202, Issue:1

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Apoptosis; Glucosides; Herbicides; Nervous System; Neuroprotective Agents; PC12 Cells; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Signal Transduction; Stilbenes

2011
Antimicrobial activities of the methanol extract, fractions and compounds from Ficus polita Vahl. (Moraceae).
    BMC complementary and alternative medicine, 2011, Jan-26, Volume: 11

    Topics: Anti-Bacterial Agents; Antifungal Agents; Bacteria; Chloramphenicol; Ficus; Fungi; Glucosides; Microbial Sensitivity Tests; Plant Extracts; Plant Roots; Pseudomonas; Stilbenes

2011
Kinetics and mechanism of 2,3,5,4'-tetrahydroxystilbene-2-O-β-d-glycoside (THSG) degradation in aqueous solutions.
    Journal of pharmaceutical and biomedical analysis, 2011, Apr-28, Volume: 55, Issue:1

    Topics: Chromatography, High Pressure Liquid; Drug Stability; Glucosides; Hot Temperature; Hydrogen-Ion Concentration; Hydrolysis; Hypolipidemic Agents; Isomerism; Kinetics; Light; Oxidation-Reduction; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Stilbenes

2011
Occurrence of C-glucoside of resveratrol oligomers in Hopea parviflora.
    Chemical & pharmaceutical bulletin, 2011, Volume: 59, Issue:2

    Topics: Dipterocarpaceae; Glucosides; Plant Bark; Plant Extracts; Resveratrol; Stilbenes

2011
Effect of polydatin on action potential in ventricular papillary muscle of rat and the underlying ionic mechanism.
    Sheng li xue bao : [Acta physiologica Sinica], 2011, Feb-25, Volume: 63, Issue:1

    Topics: Action Potentials; Animals; Calcium Channels, L-Type; Drugs, Chinese Herbal; Glucosides; Heart Ventricles; KATP Channels; Male; Papillary Muscles; Rats; Rats, Sprague-Dawley; Stilbenes

2011
2,3,4',5-Tetrahydroxystilbene-2-O-β-d-glucoside inhibits platelet-derived growth factor-induced proliferation of vascular smooth muscle cells by regulating the cell cycle.
    Clinical and experimental pharmacology & physiology, 2011, Volume: 38, Issue:5

    Topics: Animals; Becaplermin; Cardiovascular Agents; Cell Cycle; Cell Cycle Proteins; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Down-Regulation; Drug Evaluation, Preclinical; Gene Expression Regulation; Glucosides; Male; Models, Biological; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Rats; Rats, Sprague-Dawley; Stilbenes

2011
[Effect of polydatin on dynamic changes of excitatory amino acids in cerebrospinal fluid of cerebral hemorrhage rats].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2010, Volume: 35, Issue:22

    Topics: Animals; Aspartic Acid; Cerebral Hemorrhage; Disease Models, Animal; Drugs, Chinese Herbal; Excitatory Amino Acids; Glucosides; Glutamic Acid; Humans; Male; Rats; Rats, Sprague-Dawley; Stilbenes

2010
Anti-inflammatory effect of resveratrol and polydatin by in vitro IL-17 modulation.
    Inflammation, 2012, Volume: 35, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; CD28 Antigens; CD3 Complex; Cells, Cultured; Drugs, Chinese Herbal; Glucosides; Humans; Interleukin-17; Leukocytes, Mononuclear; Resveratrol; RNA, Messenger; Stilbenes

2012
An automatic optosensing device for the simultaneous determination of resveratrol and piceid in wines.
    Analytica chimica acta, 2011, Mar-18, Volume: 689, Issue:2

    Topics: Automation; Chromatography, High Pressure Liquid; Glucosides; Limit of Detection; Resveratrol; Solid Phase Extraction; Spectrometry, Fluorescence; Stilbenes; Wine

2011
[Optimization of ultrahigh pressure extraction for polydatin and resveratrol from Polygonum cuspidatum by using uniform design].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2010, Volume: 35, Issue:24

    Topics: Calibration; Chemical Fractionation; Fallopia japonica; Glucosides; Pressure; Reproducibility of Results; Resveratrol; Solvents; Stilbenes; Time Factors

2010
Tetrahydroxystilbene glucoside protects human neuroblastoma SH-SY5Y cells against MPP+-induced cytotoxicity.
    European journal of pharmacology, 2011, Jun-25, Volume: 660, Issue:2-3

    Topics: 1-Methyl-4-phenylpyridinium; bcl-2-Associated X Protein; Caspase 3; Cell Line, Tumor; Cell Membrane; Cell Survival; Cytoprotection; Gene Expression Regulation; Glucosides; Humans; Mitochondria; Neuroblastoma; Neuroprotective Agents; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Stilbenes

2011
Simultaneous analysis of serotonin, melatonin, piceid and resveratrol in fruits using liquid chromatography tandem mass spectrometry.
    Journal of chromatography. A, 2011, Jun-24, Volume: 1218, Issue:25

    Topics: Chromatography, High Pressure Liquid; Citrus sinensis; Fruit; Glucosides; Melatonin; Reproducibility of Results; Resveratrol; Sensitivity and Specificity; Serotonin; Stilbenes; Tandem Mass Spectrometry; Vitis

2011
Effect of ZnO#ZnS QDs heterojunctures on the stilbenes-plasma proteins interactions.
    Molecular bioSystems, 2011, Volume: 7, Issue:8

    Topics: Animals; Binding Sites; Biological Availability; Blood Proteins; Cattle; Glucosides; Kinetics; Particle Size; Protein Binding; Quantum Dots; Resveratrol; Stilbenes; Zinc Oxide; Zinc Sulfate

2011
Pharmacokinetics and tissue distribution of 2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside from traditional Chinese medicine Polygonum multiflorum following oral administration to rats.
    Journal of ethnopharmacology, 2011, Sep-01, Volume: 137, Issue:1

    Topics: Administration, Oral; Animals; Calibration; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Drugs, Chinese Herbal; Glucosides; Liquid-Liquid Extraction; Male; Medicine, Chinese Traditional; Models, Biological; Plant Roots; Polygonaceae; Rats; Rats, Sprague-Dawley; Reference Standards; Reproducibility of Results; Spectrophotometry, Ultraviolet; Stilbenes; Tissue Distribution

2011
Overexpression of a resveratrol synthase gene (PcRS) from Polygonum cuspidatum in transgenic Arabidopsis causes the accumulation of trans-piceid with antifungal activity.
    Plant cell reports, 2011, Volume: 30, Issue:11

    Topics: Acyltransferases; Antifungal Agents; Arabidopsis; Chromatography, High Pressure Liquid; Colletotrichum; Crosses, Genetic; Disease Resistance; Fallopia japonica; Genes, Plant; Glucosides; Pigmentation; Plant Diseases; Plant Leaves; Plants, Genetically Modified; Seeds; Spectrometry, Mass, Electrospray Ionization; Stilbenes

2011
Study on the structural changes of bovine serum albumin with effects on polydatin binding by a multitechnique approach.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2011, Oct-15, Volume: 81, Issue:1

    Topics: Animals; Cattle; Chemistry, Analytic; Circular Dichroism; Glucosides; Models, Biological; Molecular Structure; Protein Binding; Serum Albumin, Bovine; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Stilbenes; Structure-Activity Relationship

2011
Effectiveness of the association micronized N-palmitoylethanolamine (PEA)-transpolydatin in the treatment of chronic pelvic pain.
    European journal of obstetrics, gynecology, and reproductive biology, 2011, Volume: 159, Issue:2

    Topics: Analgesics; Endometriosis; Female; Glucosides; Humans; Palmitic Acids; Pelvic Pain; Stilbenes

2011
Polydatin up-regulates Clara cell secretory protein to suppress phospholipase A2 of lung induced by LPS in vivo and in vitro.
    BMC cell biology, 2011, Jul-25, Volume: 12

    Topics: Animals; Cell Line; Glucosides; Humans; Immunohistochemistry; Lipopolysaccharides; Lung; Lung Injury; Male; Phospholipase A2 Inhibitors; Phospholipases A2; Rats; Rats, Sprague-Dawley; RNA, Messenger; Stilbenes; Up-Regulation; Uteroglobin

2011
Cardioprotective effect of polydatin against ischemia/reperfusion injury: roles of protein kinase C and mito K(ATP) activation.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2011, Dec-15, Volume: 19, Issue:1

    Topics: Animals; Antioxidants; Cardiotonic Agents; Creatine Kinase; Disease Models, Animal; Drugs, Chinese Herbal; Enzyme Inhibitors; Fallopia japonica; Glucosides; Injections, Intravenous; KATP Channels; L-Lactate Dehydrogenase; Male; Malondialdehyde; Mitochondria; Myocardial Reperfusion Injury; Oxidative Stress; Phytotherapy; Protein Kinase C; Random Allocation; Rats; Rats, Sprague-Dawley; Signal Transduction; Stilbenes; Superoxide Dismutase

2011
Interaction of dietary polyphenols with bovine milk proteins: molecular structure-affinity relationship and influencing bioactivity aspects.
    Molecular nutrition & food research, 2011, Volume: 55, Issue:11

    Topics: Esterification; Flavones; Flavonoids; Flavonols; Food-Drug Interactions; Free Radical Scavengers; Glucosides; Glycosylation; Hydrogenation; Hydroxylation; Kinetics; Methylation; Milk Proteins; Polyphenols; Protein Binding; Stilbenes; Structure-Activity Relationship

2011
Reactive oxygen species-mediated endoplasmic reticulum stress and mitochondrial dysfunction contribute to polydatin-induced apoptosis in human nasopharyngeal carcinoma CNE cells.
    Journal of cellular biochemistry, 2011, Volume: 112, Issue:12

    Topics: Apoptosis; Base Sequence; Caspases; Cell Line, Tumor; Cytochromes c; Endoplasmic Reticulum; Glucosides; Humans; Mitochondria; Nasopharyngeal Neoplasms; Phosphorylation; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; RNA, Small Interfering; Stilbenes; Stress, Physiological

2011
Hepatoxicity of major constituents and extractions of Radix Polygoni Multiflori and Radix Polygoni Multiflori Praeparata.
    Journal of ethnopharmacology, 2011, Oct-11, Volume: 137, Issue:3

    Topics: Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Cell Line; Cell Proliferation; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Emodin; Glucosides; Humans; L-Lactate Dehydrogenase; Liver; Plant Roots; Plants, Medicinal; Polygonaceae; Solvents; Stilbenes

2011
[Effect of polydatin on learning and memory and expression of NR2B in the prefrontal cortex of rats with chronic alcoholism].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2011, Volume: 27, Issue:2

    Topics: Alcoholism; Animals; Drugs, Chinese Herbal; Glucosides; Male; Maze Learning; Memory Disorders; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Stilbenes

2011
Biosynthesis of the major tetrahydroxystilbenes in spruce, astringin and isorhapontin, proceeds via resveratrol and is enhanced by fungal infection.
    Plant physiology, 2011, Volume: 157, Issue:2

    Topics: Acyl Coenzyme A; Acyltransferases; Amino Acid Sequence; Ascomycota; Coenzyme A Ligases; Conserved Sequence; Escherichia coli; Glucosides; Glycosylation; Host-Pathogen Interactions; Hydroxylation; Malonyl Coenzyme A; Methylation; Molecular Sequence Data; Phylogeny; Picea; Plant Diseases; Plant Proteins; Plants, Genetically Modified; Resveratrol; Stilbenes

2011
Pharmacokinetic profile of 2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside in mice after oral administration of Polygonum multiflorum extract.
    Drug development and industrial pharmacy, 2012, Volume: 38, Issue:2

    Topics: Administration, Oral; Animals; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Drugs, Chinese Herbal; Glucosides; Male; Medicine, Chinese Traditional; Mice; Models, Animal; Plant Preparations; Plant Roots; Plants, Medicinal; Polygonum; Stilbenes

2012
Resveratrol derivative-rich melinjo (Gnetum gnemon L.) seed extract suppresses multiple angiogenesis-related endothelial cell functions and tumor angiogenesis.
    Molecular nutrition & food research, 2011, Volume: 55, Issue:11

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Phytogenic; Biological Assay; Cell Movement; Cell Proliferation; Cell Survival; Cells, Cultured; Drug Discovery; Female; Glucosides; Gnetum; Human Umbilical Vein Endothelial Cells; Humans; Mice; Mice, Inbred ICR; Neovascularization, Pathologic; Plant Extracts; Resveratrol; Seeds; Stilbenes

2011
Inhibitory effect of mulberroside A and its derivatives on melanogenesis induced by ultraviolet B irradiation.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2011, Volume: 49, Issue:12

    Topics: Animals; Disaccharides; Glucosides; Guinea Pigs; Melanins; Microphthalmia-Associated Transcription Factor; Monophenol Monooxygenase; Morus; Oxidoreductases; Plant Extracts; Plant Roots; Skin; Stilbenes; Ultraviolet Rays

2011
Anthraquinones and stilbenes from the roots and rhizomes of Rhubarb.
    Journal of Asian natural products research, 2011, Volume: 13, Issue:11

    Topics: Anthraquinones; Biphenyl Compounds; Drugs, Chinese Herbal; Free Radical Scavengers; Glucosides; Picrates; Plant Roots; Plants, Medicinal; Rheum; Rhizome; Stilbenes

2011
Beneficial effects of THSG on acetic acid-induced experimental colitis: involvement of upregulation of PPAR-γ and inhibition of the Nf-Κb inflammatory pathway.
    Molecules (Basel, Switzerland), 2011, Oct-12, Volume: 16, Issue:10

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Drugs, Chinese Herbal; Glucosides; Interleukin-6; Male; Malondialdehyde; Mesalamine; Mice; NF-kappa B; PPAR gamma; Stilbenes; Tumor Necrosis Factor-alpha

2011
Protective effect of tetrahydroxystilbene glucoside on 6-OHDA-induced apoptosis in PC12 cells through the ROS-NO pathway.
    PloS one, 2011, Volume: 6, Issue:10

    Topics: Animals; Apoptosis; Cell Nucleus; Cell Survival; Gene Expression Regulation, Enzymologic; Glucosides; Intracellular Space; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Oxidopamine; PC12 Cells; Rats; Reactive Oxygen Species; Signal Transduction; Stilbenes; Tyrosine

2011
Polydatin modulates inflammation by decreasing NF-κB activation and oxidative stress by increasing Gli1, Ptch1, SOD1 expression and ameliorates blood-brain barrier permeability for its neuroprotective effect in pMCAO rat brain.
    Brain research bulletin, 2012, Jan-04, Volume: 87, Issue:1

    Topics: Animals; Blood-Brain Barrier; Brain; Claudin-5; Claudins; Glucosides; Infarction, Middle Cerebral Artery; Inflammation; Kruppel-Like Transcription Factors; Male; Molecular Structure; Neuroprotective Agents; Neuropsychological Tests; NF-kappa B; Oxidative Stress; Patched Receptors; Patched-1 Receptor; Permeability; Random Allocation; Rats; Receptors, Cell Surface; Stilbenes; Superoxide Dismutase; Superoxide Dismutase-1; Zinc Finger Protein GLI1

2012
Tetrahydroxystilbene glucoside improves learning and (or) memory ability of aged rats and may be connected to the APP pathway.
    Canadian journal of physiology and pharmacology, 2011, Volume: 89, Issue:11

    Topics: Animals; Drug Administration Schedule; Drug Evaluation, Preclinical; Gene Expression Profiling; Glucosides; Hippocampus; Learning; Male; Maze Learning; Memory; Nootropic Agents; Rats; Rats, Sprague-Dawley; Software; Stilbenes; Time Factors

2011
An optimum fermentation model established by genetic algorithm for biotransformation from crude polydatin to resveratrol.
    Applied biochemistry and biotechnology, 2012, Volume: 166, Issue:2

    Topics: Algorithms; Aspergillus niger; Biotransformation; Fermentation; Glucosides; Models, Biological; Nonlinear Dynamics; Resveratrol; Stilbenes

2012
Toxicity of raw and processed roots of Polygonum multiflorum.
    Fitoterapia, 2012, Volume: 83, Issue:3

    Topics: Animals; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Emodin; Female; Glucosides; Humans; Male; Mice; Mice, Inbred Strains; Plant Roots; Polygonum; Stilbenes

2012
2,3,4',5-tetrahydroxystilbene-2-O-β-D-glucoside inhibits proliferation of vascular smooth muscle cells: involvement of NO/cGMP/PKG pathway.
    Phytotherapy research : PTR, 2012, Volume: 26, Issue:7

    Topics: Animals; Becaplermin; Carbazoles; Cell Cycle; Cell Proliferation; Cells, Cultured; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Glucosides; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Polygonum; Proto-Oncogene Proteins c-sis; Quinoxalines; Rats; Rats, Sprague-Dawley; Signal Transduction; Stilbenes

2012
Polydatin, a natural polyphenol, protects arterial smooth muscle cells against mitochondrial dysfunction and lysosomal destabilization following hemorrhagic shock.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2012, Volume: 302, Issue:7

    Topics: Adenosine Triphosphate; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Cyclosporine; Cytoprotection; Glucosides; KATP Channels; Lysosomes; Membrane Potential, Mitochondrial; Mitochondria, Muscle; Mitochondrial Diseases; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocytes, Smooth Muscle; Norepinephrine; Rats; Resveratrol; Shock, Hemorrhagic; Stilbenes

2012
Eradication of Propionibacterium acnes biofilms by plant extracts and putative identification of icariin, resveratrol and salidroside as active compounds.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2012, Mar-15, Volume: 19, Issue:5

    Topics: Acne Vulgaris; Biofilms; Dolichos; Drug Resistance, Bacterial; Epimedium; Flavonoids; Fruit; Glucosides; Humans; Malus; Microbial Sensitivity Tests; Phenols; Plant Extracts; Plant Roots; Polygonum; Propionibacterium acnes; Resveratrol; Rhizome; Rhodiola; Sebaceous Glands; Seeds; Stilbenes

2012
2,3,4',5-Tetrahydroxystilbene-2-O-β-D-glucoside inhibits angiotensin II-induced cardiac fibroblast proliferation via suppression of the reactive oxygen species-extracellular signal-regulated kinase 1/2 pathway.
    Clinical and experimental pharmacology & physiology, 2012, Volume: 39, Issue:5

    Topics: Angiotensin II; Animals; Animals, Newborn; Cell Proliferation; Cells, Cultured; Fibroblasts; Glucosides; Growth Inhibitors; MAP Kinase Signaling System; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Stilbenes

2012
Liquid chromatography/tandem mass spectrometry method for quantification of trans-stilbene glycoside in rat plasma and its pharmacokinetic application.
    Biomedical chromatography : BMC, 2012, Volume: 26, Issue:11

    Topics: Animals; Chromatography, Liquid; Drug Stability; Glucosides; Glycosides; Linear Models; Male; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Stilbenes; Tandem Mass Spectrometry

2012
2,3,5,4'- tetrahydroxystilbene-2-O-β-D-glycoside biosynthesis by suspension cells cultures of Polygonum multiflorum Thunb and production enhancement by methyl jasmonate and salicylic acid.
    Molecules (Basel, Switzerland), 2012, Feb-22, Volume: 17, Issue:2

    Topics: Acetates; Cell Culture Techniques; Cyclopentanes; Glucosides; Oxylipins; Plant Cells; Polygonum; Salicylic Acid; Stilbenes; Suspensions

2012
[Effects of polydatin on bleomycin-induced pulmonary fibrosis in rats].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2011, Volume: 36, Issue:24

    Topics: Animals; Bleomycin; Dinoprostone; Drugs, Chinese Herbal; Female; Glucosides; Leukotriene C4; Male; Phospholipases A2; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; Stilbenes

2011
Separation and identification of highly fluorescent compounds derived from trans-resveratrol in the leaves of Vitis vinifera infected by Plasmopara viticola.
    Molecules (Basel, Switzerland), 2012, Mar-06, Volume: 17, Issue:3

    Topics: Chromatography, High Pressure Liquid; Chromatography, Liquid; Fluorescent Dyes; Glucosides; Isomerism; Mass Spectrometry; Peronospora; Phenanthrenes; Plant Diseases; Plant Extracts; Plant Leaves; Reference Standards; Resveratrol; Stilbenes; Ultraviolet Rays; Vitis

2012
Polydatin suppresses ultraviolet B-induced cyclooxygenase-2 expression in vitro and in vivo via reduced production of reactive oxygen species.
    The British journal of dermatology, 2012, Volume: 167, Issue:4

    Topics: Animals; Cyclooxygenase 2; Drugs, Chinese Herbal; Epidermis; Glucosides; Humans; Mice; Mice, Inbred BALB C; Radiation Injuries, Experimental; Reactive Oxygen Species; Stilbenes; Sunscreening Agents; Ultraviolet Rays

2012
Polydatin protects learning and memory impairments in a rat model of vascular dementia.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2012, Jun-15, Volume: 19, Issue:8-9

    Topics: Animals; Catalase; Cells, Cultured; Dementia, Vascular; Disease Models, Animal; Drugs, Chinese Herbal; Fallopia japonica; Glucosides; Hippocampus; Learning; Male; Malondialdehyde; Maze Learning; Memory Disorders; Neurons; Neuroprotective Agents; Protective Agents; Rats; Rats, Sprague-Dawley; Stilbenes; Superoxide Dismutase

2012
Multiparameter evaluation of the longevity in C. elegans under stress using an integrated microfluidic device.
    Biomedical microdevices, 2012, Volume: 14, Issue:4

    Topics: Animals; Animals, Genetically Modified; Caenorhabditis elegans; Copper; Glucosides; Longevity; Microfluidic Analytical Techniques; Oxidative Stress; Stilbenes; Systems Integration; Time Factors

2012
Protective effect of tetrahydroxystilbene glucoside against hydrogen peroxide-induced dysfunction and oxidative stress in osteoblastic MC3T3-E1 cells.
    European journal of pharmacology, 2012, Aug-15, Volume: 689, Issue:1-3

    Topics: 3T3 Cells; Animals; Cell Survival; Cytoprotection; Glucosides; Hydrogen Peroxide; Mice; Osteoblasts; Oxidative Stress; Stilbenes

2012
Polydatin ameliorates experimental diabetes-induced fibronectin through inhibiting the activation of NF-κB signaling pathway in rat glomerular mesangial cells.
    Molecular and cellular endocrinology, 2012, Oct-15, Volume: 362, Issue:1-2

    Topics: Active Transport, Cell Nucleus; Animals; Anti-Inflammatory Agents; Cell Nucleus; Cells, Cultured; Cytoprotection; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Drugs, Chinese Herbal; Fibronectins; Gene Expression; Glucosides; I-kappa B Proteins; Intercellular Adhesion Molecule-1; Kidney; Male; Mesangial Cells; NF-kappa B; NF-KappaB Inhibitor alpha; Organ Size; Protein Binding; Proteolysis; Rats; Rats, Sprague-Dawley; Signal Transduction; Stilbenes; Transforming Growth Factor beta

2012
[Effect of polydatin on expression of cdk5 in the prefrontal cortex of rats with chronic alcoholism].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2012, Volume: 28, Issue:2

    Topics: Alcoholism; Animals; Cyclin-Dependent Kinase 5; Glucosides; Male; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Stilbenes

2012
[Impact of 2, 3-dihydrocyclopentacoumarins to growth of transgenic hairy roots of Polygonum multiflorum and accumulation of stilbene glucosides].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2012, Volume: 37, Issue:9

    Topics: Coumarins; Glucosides; Plant Roots; Polygonum; Stilbenes

2012
Enzymatic synthesis of piceid glucosides using maltosyltransferase from Caldicellulosiruptor bescii DSM 6725.
    Journal of agricultural and food chemistry, 2012, Aug-22, Volume: 60, Issue:33

    Topics: alpha-Glucosidases; Bacteria; Biological Availability; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Escherichia coli; Glucosides; Glucosyltransferases; Magnetic Resonance Spectroscopy; Molecular Structure; Recombinant Proteins; Resveratrol; Solubility; Stilbenes

2012
Polydatin attenuates hypoxic pulmonary hypertension and reverses remodeling through protein kinase C mechanisms.
    International journal of molecular sciences, 2012, Volume: 13, Issue:6

    Topics: Angiotensin II; Animals; Endothelins; Glucosides; Hypertension, Pulmonary; Hypoxia; Male; Nitric Oxide; Phorbol Esters; Protein Kinase C; Rats; Rats, Sprague-Dawley; Signal Transduction; Stilbenes; Vascular Remodeling

2012
Polydatin alleviates non-alcoholic fatty liver disease in rats by inhibiting the expression of TNF-α and SREBP-1c.
    Molecular medicine reports, 2012, Volume: 6, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Cholesterol; Diet, High-Fat; Fallopia japonica; Fatty Acid Synthases; Fatty Acids, Nonesterified; Fatty Liver; Glucosides; Lipid Peroxidation; Lipogenesis; Liver; Male; Non-alcoholic Fatty Liver Disease; Protective Agents; Rats; Rats, Sprague-Dawley; Rhizome; Stearoyl-CoA Desaturase; Sterol Regulatory Element Binding Protein 1; Stilbenes; Triglycerides; Tumor Necrosis Factor-alpha

2012
Antihyperuricemic and nephroprotective effects of resveratrol and its analogues in hyperuricemic mice.
    Molecular nutrition & food research, 2012, Volume: 56, Issue:9

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Blood Urea Nitrogen; Carrier Proteins; Creatinine; Disaccharides; Gene Expression Regulation; Glucose Transport Proteins, Facilitative; Glucosides; Gout Suppressants; Hyperuricemia; Kidney; Male; Membrane Proteins; Mice; Mice, Inbred Strains; Octamer Transcription Factor-1; Organic Anion Transport Protein 1; Organic Anion Transporters; Organic Cation Transport Proteins; Organic Cation Transporter 2; Oxonic Acid; Resveratrol; Solute Carrier Family 22 Member 5; Stilbenes; Symporters; Uric Acid

2012
Glycosylation of trans-resveratrol by plant-cultured cells.
    Bioscience, biotechnology, and biochemistry, 2012, Volume: 76, Issue:8

    Topics: Biotransformation; Catharanthus; Cells, Cultured; Glucose; Glucosides; Glycosides; Glycosylation; Ipomoea batatas; Molecular Structure; Plant Cells; Resveratrol; Stereoisomerism; Stilbenes; Strophanthus

2012
Polydatin modulates Ca(2+) handling, excitation-contraction coupling and β-adrenergic signaling in rat ventricular myocytes.
    Journal of molecular and cellular cardiology, 2012, Volume: 53, Issue:5

    Topics: Adrenergic beta-Agonists; Animals; Calcium; Calcium Channels, L-Type; Cardiotonic Agents; Cell Survival; Excitation Contraction Coupling; Female; Glucosides; Heart Ventricles; Male; Membrane Potentials; Myocardial Contraction; Myocytes, Cardiac; Myofibrils; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Stilbenes

2012
Microbial metabolism. Part 14. Isolation and bioactivity evaluation of microbial metabolites of resveratrol.
    Natural product research, 2013, Volume: 27, Issue:16

    Topics: Beauveria; Glucosides; Magnetic Resonance Spectroscopy; Molecular Structure; Penicillium chrysogenum; Resveratrol; Stilbenes

2013
Polydatin, a natural precursor of resveratrol, induces β-defensin production and reduces inflammatory response.
    Inflammation, 2013, Volume: 36, Issue:1

    Topics: beta-Defensins; Cell Line; Cytoprotection; Enzyme-Linked Immunosorbent Assay; Gene Expression; Glucosides; Heat-Shock Response; HSP70 Heat-Shock Proteins; Humans; Inflammation; Interleukin-6; Interleukin-8; Keratinocytes; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes; Tumor Necrosis Factor-alpha

2013
Polydatin (PD) inhibits IgE-mediated passive cutaneous anaphylaxis in mice by stabilizing mast cells through modulating Ca²⁺ mobilization.
    Toxicology and applied pharmacology, 2012, Nov-01, Volume: 264, Issue:3

    Topics: Animals; Calcium; Cell Line; Drugs, Chinese Herbal; Female; Gene Expression Regulation; Glucosides; Immunoglobulin E; Mast Cells; Mice; Mice, Inbred BALB C; Passive Cutaneous Anaphylaxis; Reactive Oxygen Species; Receptors, IgE; Stilbenes

2012
2,3,5,4'-tetrahydroxystilbene-2-O-β-d-glucoside ameliorates vascular senescence and improves blood flow involving a mechanism of p53 deacetylation.
    Atherosclerosis, 2012, Volume: 225, Issue:1

    Topics: Aging; Animals; Carotid Arteries; Cellular Senescence; Glucosides; Human Umbilical Vein Endothelial Cells; Humans; Male; Nitric Oxide Synthase Type III; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Regional Blood Flow; Sirtuin 1; Stilbenes; Tumor Suppressor Protein p53

2012
Protective effects of polydatin from Polygonum cuspidatum against carbon tetrachloride-induced liver injury in mice.
    PloS one, 2012, Volume: 7, Issue:9

    Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Antioxidants; Aspartate Aminotransferases; Carbon Tetrachloride; Catalase; Chemical and Drug Induced Liver Injury; Drugs, Chinese Herbal; Fallopia japonica; Gene Expression; Glucosides; Glutathione; Glutathione Peroxidase; Glutathione Transferase; Inflammation Mediators; Liver; Male; Mice; Mice, Inbred ICR; NF-kappa B; Oxidative Stress; Stilbenes; Superoxide Dismutase; Transforming Growth Factor beta1; Up-Regulation

2012
Differential cell-protective function of two resveratrol (trans-3,5,4'-trihydroxystilbene) glucosides against oxidative stress.
    The Journal of pharmacology and experimental therapeutics, 2013, Volume: 344, Issue:1

    Topics: Animals; Animals, Newborn; Antioxidants; Apoptosis; Biphenyl Compounds; Blotting, Western; Cell Death; Cell Line; Cells, Cultured; Chromans; Cytoprotection; Free Radical Scavengers; Free Radicals; Glucosides; Immunohistochemistry; Mice; Myoblasts; Myocytes, Cardiac; Oxidative Stress; Phytolacca americana; Picrates; Polymerase Chain Reaction; Rats; Resveratrol; Sirtuin 1; Stilbenes

2013
Inhibition of DNA topoisomerases I and II of compounds from Reynoutria japonica.
    Archives of pharmacal research, 2012, Volume: 35, Issue:9

    Topics: Animals; Anthraquinones; Antigens, Neoplasm; Antineoplastic Agents, Phytogenic; Benzyl Alcohols; Cattle; Cell Line, Tumor; DNA Topoisomerases, Type II; DNA-Binding Proteins; Drug Discovery; Fallopia japonica; Glucosides; Humans; Inhibitory Concentration 50; Medicine, Korean Traditional; Neoplasms; Plant Extracts; Plant Roots; Republic of Korea; Resorcinols; Stilbenes; Topoisomerase I Inhibitors; Transition Temperature

2012
Analysis and functionality of major polyphenolic components of Polygonum cuspidatum (itadori).
    Journal of nutritional science and vitaminology, 2012, Volume: 58, Issue:4

    Topics: alpha-Glucosidases; Antioxidants; Chlorogenic Acid; Enzyme Inhibitors; Fallopia japonica; Glucosides; Glycoside Hydrolase Inhibitors; Plant Extracts; Plant Leaves; Plant Roots; Plants, Medicinal; Polyphenols; Resveratrol; Stilbenes

2012
Polydatin ameliorates renal injury by attenuating oxidative stress-related inflammatory responses in fructose-induced urate nephropathic mice.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 52

    Topics: Animals; Blood Chemical Analysis; Body Weight; Cyclooxygenase 2; Dinoprostone; Disease Models, Animal; Drugs, Chinese Herbal; Fructose; Glucosides; Inflammation; Interleukin-1beta; Kidney; Kidney Diseases; Male; Mice; Mice, Inbred Strains; NF-kappa B; Nitric Oxide Synthase Type II; Oxidative Stress; Protective Agents; Stilbenes; Tumor Necrosis Factor-alpha; Uric Acid; Xanthine Oxidase

2013
Localization of phenolics in phloem parenchyma cells of Norway spruce (Picea abies).
    Chembiochem : a European journal of chemical biology, 2012, Dec-21, Volume: 13, Issue:18

    Topics: Ascomycota; Biological Transport; Disease Resistance; Glucosides; Phenols; Phloem; Picea; Plant Bark; Plant Diseases; Stilbenes

2012
Tetrahydroxystilbene glucoside antagonizes age-related α-synuclein overexpression in the hippocampus of APP transgenic mouse model of Alzheimer's disease.
    Restorative neurology and neuroscience, 2013, Volume: 31, Issue:1

    Topics: Aging; alpha-Synuclein; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Blotting, Western; Brain Chemistry; Data Interpretation, Statistical; DNA, Complementary; Glucosides; Hippocampus; Humans; Immunohistochemistry; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microarray Analysis; Nootropic Agents; Real-Time Polymerase Chain Reaction; RNA, Messenger; Stilbenes

2013
The effect of 2,3,4',5-tetrahydroxystilbene-2-0-β-D glucoside on neointima formation in a rat artery balloon injury model and its possible mechanisms.
    European journal of pharmacology, 2013, Jan-05, Volume: 698, Issue:1-3

    Topics: Animals; Becaplermin; Carotid Arteries; Carotid Artery Injuries; Catheters; Cell Movement; Extracellular Matrix; Gene Expression Regulation; Glucosides; Hyperplasia; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Neointima; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-sis; Rats; Rats, Sprague-Dawley; Signal Transduction; Stilbenes

2013
Tetrahydroxystilbene glucoside improves the learning and memory of amyloid-β(₁₋₄₂)-injected rats and may be connected to synaptic changes in the hippocampus.
    Canadian journal of physiology and pharmacology, 2012, Volume: 90, Issue:11

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Disease Models, Animal; Glucosides; Hippocampus; Learning Disabilities; Male; Memory Disorders; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Nootropic Agents; Peptide Fragments; Proto-Oncogene Proteins pp60(c-src); Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Stilbenes; Synaptic Membranes; Up-Regulation

2012
Proteomic analysis for anti-atherosclerotic effect of tetrahydroxystilbene glucoside in rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2013, Volume: 67, Issue:2

    Topics: Animals; Annexin A1; Aorta; Apolipoprotein A-I; Apoptosis; Atherosclerosis; Calreticulin; Cell Adhesion; Cholesterol; Down-Regulation; Gene Expression Regulation; Glucosides; HSP70 Heat-Shock Proteins; Inflammation; Male; Proteome; Proteomics; Rats; Rats, Sprague-Dawley; Stilbenes; Up-Regulation; Vimentin

2013
Modulation of human keratinocyte responses to solar UV by plant polyphenols as a basis for chemoprevention of non-melanoma skin cancers.
    Current medicinal chemistry, 2013, Volume: 20, Issue:7

    Topics: Aryl Hydrocarbon Hydroxylases; Carbazoles; Cell Proliferation; Cell Survival; Cells, Cultured; Chemoprevention; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Cytokines; Glucosides; Humans; Keratinocytes; Oxidation-Reduction; Phenols; Polyphenols; Skin Neoplasms; Squalene; Stilbenes; Ultraviolet Rays

2013
Bioconversion of piceid to piceid glucoside using amylosucrase from Alteromonas macleodii deep ecotype.
    Journal of microbiology and biotechnology, 2012, Volume: 22, Issue:12

    Topics: Alteromonas; Bacterial Proteins; Bioreactors; Escherichia coli; Glucosides; Glucosyltransferases; Glycosylation; Hydrogen-Ion Concentration; Nuclear Magnetic Resonance, Biomolecular; Recombinant Proteins; Solubility; Stilbenes; Temperature

2012
2, 3, 5, 4'-Tetrahydroxystilbene-2-O-beta-D-glucoside improves gastrointestinal motility disorders in STZ-induced diabetic mice.
    PloS one, 2012, Volume: 7, Issue:12

    Topics: Animals; Caspase 3; Diabetes Mellitus, Experimental; Gastrointestinal Motility; Glucosides; Glutathione Peroxidase; Malondialdehyde; Mice; Nitric Oxide Synthase Type I; Oxidative Stress; Phosphorylation; Stilbenes; Streptozocin

2012
Polydatin--a new mitochondria protector for acute severe hemorrhagic shock treatment.
    Expert opinion on investigational drugs, 2013, Volume: 22, Issue:2

    Topics: Acute Disease; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Glucosides; Lipid Peroxidation; Lipid Peroxides; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Neurons; Parietal Lobe; Protective Agents; Rats; Rats, Wistar; Severity of Illness Index; Shock, Hemorrhagic; Stilbenes; Survival Analysis

2013
Stilbenoid profiles of canes from Vitis and Muscadinia species.
    Journal of agricultural and food chemistry, 2013, Jan-23, Volume: 61, Issue:3

    Topics: Benzofurans; Chromatography, High Pressure Liquid; Flavonoids; Glucosides; Magnetic Resonance Spectroscopy; Phenols; Resveratrol; Stilbenes; Vitis

2013
Chemical constituents of Caesalpinia decapetala (Roth) Alston.
    Molecules (Basel, Switzerland), 2013, Jan-22, Volume: 18, Issue:1

    Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Ascorbic Acid; Benzopyrans; Benzyl Alcohols; Biphenyl Compounds; Caesalpinia; Cell Line, Tumor; Cell Survival; Emodin; Flavonoids; Free Radical Scavengers; Free Radicals; Glucosides; Humans; Inhibitory Concentration 50; Molecular Structure; Picrates; Plant Extracts; Stilbenes; Triterpenes

2013
Comparision of piceid and resveratrol in antioxidation and antiproliferation activities in vitro.
    PloS one, 2013, Volume: 8, Issue:1

    Topics: Antioxidants; Cell Line, Tumor; Cell Proliferation; Glucosides; Hep G2 Cells; Humans; Resveratrol; Stilbenes

2013
Assessing the regioselectivity of OleD-catalyzed glycosylation with a diverse set of acceptors.
    Journal of natural products, 2013, Feb-22, Volume: 76, Issue:2

    Topics: Bacterial Proteins; Catalysis; Glucosides; Glucosyltransferases; Glycosylation; Isoflavones; Resveratrol; Stereoisomerism; Stilbenes; Streptomyces antibioticus

2013
Pharmacokinetics of 2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside in rat using ultra-performance LC-quadrupole TOF-MS.
    Journal of separation science, 2013, Volume: 36, Issue:5

    Topics: Animals; Bile; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Feces; Glucosides; Male; Mass Spectrometry; Rats; Rats, Sprague-Dawley; Stilbenes; Tissue Distribution

2013
The adjuvant use of N-palmitoylethanolamine and transpolydatin in the treatment of endometriotic pain.
    European journal of obstetrics, gynecology, and reproductive biology, 2013, Volume: 168, Issue:2

    Topics: Adult; Amides; Anti-Inflammatory Agents, Non-Steroidal; Chronic Pain; Contraceptives, Oral, Combined; Drug Combinations; Drug Therapy, Combination; Dysmenorrhea; Endocannabinoids; Endometriosis; Ethanolamines; Fascia; Female; Female Urogenital Diseases; Glucosides; Humans; Middle Aged; Ovarian Diseases; Pain Measurement; Palmitic Acids; Pelvic Pain; Prospective Studies; Stereoisomerism; Stilbenes; Young Adult

2013
Protective effects of polydatin on septic lung injury in mice via upregulation of HO-1.
    Mediators of inflammation, 2013, Volume: 2013

    Topics: Animals; Bronchoalveolar Lavage Fluid; Glucosides; Heme Oxygenase-1; Interleukin-6; Lung Injury; Mice; Nitric Oxide; Random Allocation; Sepsis; Stilbenes; Transcription Factor RelA; Tumor Necrosis Factor-alpha

2013
Arginase inhibition by piceatannol-3'-O-β-D-glucopyranoside improves endothelial dysfunction via activation of endothelial nitric oxide synthase in ApoE-null mice fed a high-cholesterol diet.
    International journal of molecular medicine, 2013, Volume: 31, Issue:4

    Topics: Analysis of Variance; Animals; Aorta; Apolipoproteins E; Arginase; Diet, High-Fat; Enzyme Stability; Glucosides; Male; Mice; Mice, Knockout; Nitric Oxide Synthase Type III; Plaque, Atherosclerotic; Stilbenes; Vasoconstriction

2013
Anti-estrogenic activity of a human resveratrol metabolite.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2013, Volume: 23, Issue:11

    Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Binding Sites; Breast Neoplasms; Cell Line, Tumor; Clone Cells; Estrogen Antagonists; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Glucosides; Glucuronides; Humans; MCF-7 Cells; Neoplasm Proteins; Nuclear Receptor Coactivator 2; Peptide Fragments; Phytoestrogens; Recombinant Proteins; Resveratrol; Stereoisomerism; Stilbenes; Sulfates

2013
Synthesis of 3,5,3',4'-tetrahydroxy-trans-stilbene-4'-O-beta-D-glucopyranoside by glucosyltransferases from Phytolacca americana.
    Natural product communications, 2013, Volume: 8, Issue:1

    Topics: Glucosides; Glucosyltransferases; Phytolacca americana; Stereoisomerism; Stilbenes

2013
Creation of resveratrol-enriched rice for the treatment of metabolic syndrome and related diseases.
    PloS one, 2013, Volume: 8, Issue:3

    Topics: Acyltransferases; Adipose Tissue; Animals; Blood Glucose; Body Weight; Chromatography, High Pressure Liquid; Female; Food, Fortified; Glucosides; Glucosyltransferases; Humans; Lipids; Metabolic Syndrome; Mice; Mice, Inbred C57BL; Oryza; Plant Leaves; Plants, Genetically Modified; Resveratrol; Seeds; Sirtuin 1; Stilbenes

2013
Pre-column incubation followed by fast liquid chromatography analysis for rapid screening of natural methylglyoxal scavengers directly from herbal medicines: case study of Polygonum cuspidatum.
    Journal of chromatography. A, 2013, Apr-19, Volume: 1286

    Topics: Chromatography, High Pressure Liquid; Fallopia japonica; Glucosides; Glycation End Products, Advanced; Humans; Hydrogen-Ion Concentration; Mass Spectrometry; Plant Preparations; Pyruvaldehyde; Resveratrol; Serum Albumin; Stilbenes

2013
Polydatin protects cardiac function against burn injury by inhibiting sarcoplasmic reticulum Ca2+ leak by reducing oxidative modification of ryanodine receptors.
    Free radical biology & medicine, 2013, Volume: 60

    Topics: Animals; Burns; Calcium; Glucosides; Heart Injuries; Myocytes, Cardiac; Oxidation-Reduction; Oxidative Stress; Rats; Reactive Oxygen Species; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Stilbenes

2013
Stilbene glucoside inhibits the glucuronidation of emodin in rats through the down-regulation of UDP-glucuronosyltransferases 1A8: application to a drug-drug interaction study in Radix Polygoni Multiflori.
    Journal of ethnopharmacology, 2013, May-20, Volume: 147, Issue:2

    Topics: Animals; Down-Regulation; Drug Interactions; Emodin; Glucosides; Glucuronides; Glucuronosyltransferase; Intestinal Mucosa; Liver; Male; Plant Extracts; Plant Roots; Polygonum; Rats; Rats, Wistar; RNA, Messenger; Stilbenes

2013
Resveratrol induces long-lasting IL-8 expression and peculiar EGFR activation/distribution in human keratinocytes: mechanisms and implications for skin administration.
    PloS one, 2013, Volume: 8, Issue:3

    Topics: Administration, Cutaneous; Blotting, Western; Cell Cycle; Cell Membrane; Cell Nucleus; Cell Proliferation; Cytoplasm; DNA Primers; Enzyme-Linked Immunosorbent Assay; ErbB Receptors; Gene Expression Regulation; Glucosides; Humans; Interleukin-8; Keratinocytes; Phenols; Phosphorylation; Real-Time Polymerase Chain Reaction; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes; Time Factors

2013
Activation of mitochondrial function and Hb expression in non-haematopoietic cells by an EPO inducer ameliorates ischaemic diseases in mice.
    British journal of pharmacology, 2013, Volume: 169, Issue:7

    Topics: Animals; Cardiovascular Diseases; Cell Line; Cells, Cultured; Cisplatin; Doxorubicin; Erythropoietin; Glucosides; HEK293 Cells; Hemoglobins; Hepatocytes; Humans; Kidney; Male; Mice; Mice, Inbred C57BL; Mitochondria; Myocytes, Cardiac; Receptors, Erythropoietin; Stilbenes

2013
Cardioprotective effect of resveratrol and resveratroloside.
    Cardiovascular & hematological agents in medicinal chemistry, 2013, Volume: 11, Issue:3

    Topics: Animals; Cardiotonic Agents; Dose-Response Relationship, Drug; Glucosides; Infusions, Parenteral; Male; Myocardial Infarction; Rats; Rats, Wistar; Reference Standards; Resveratrol; Stilbenes; Treatment Outcome

2013
Biotransformation of polydatin to resveratrol in Polygonum cuspidatum roots by highly immobilized edible Aspergillus niger and Yeast.
    Bioresource technology, 2013, Volume: 136

    Topics: Aspergillus niger; Biotransformation; Cells, Immobilized; Fallopia japonica; Glucosides; Plant Roots; Recycling; Resveratrol; Saccharomyces cerevisiae; Stilbenes

2013
2,3,4',5-tetrahydroxystilbene-2-O-β-D-glucoside suppresses expression of adhesion molecules in aortic wall of dietary atherosclerotic rats and promonocytic U937 cells.
    Cell biochemistry and biophysics, 2013, Volume: 67, Issue:3

    Topics: Animals; Aorta; Atherosclerosis; Cell Adhesion Molecules; Diet, High-Fat; Gene Expression Regulation; Glucosides; Humans; Intercellular Adhesion Molecule-1; Lipoproteins, LDL; Male; Monocyte-Macrophage Precursor Cells; Rats; Rats, Sprague-Dawley; RNA, Messenger; Simvastatin; Stilbenes; U937 Cells; Vascular Cell Adhesion Molecule-1

2013
Enhanced physical and oxidative stabilities of soy protein-based emulsions by incorporation of a water-soluble stevioside-resveratrol complex.
    Journal of agricultural and food chemistry, 2013, May-08, Volume: 61, Issue:18

    Topics: Antioxidants; Diterpenes, Kaurane; Emulsions; Glucosides; Hydrophobic and Hydrophilic Interactions; Lipid Peroxides; Micelles; Oxidation-Reduction; Particle Size; Resveratrol; Solubility; Soybean Proteins; Spectrometry, Fluorescence; Stilbenes; Water

2013
Influence of processing on pharmacokinetic of typical constituents in radix polygoni multiflori after oral administration by LC-ESI-MS/MS.
    Journal of ethnopharmacology, 2013, Jun-21, Volume: 148, Issue:1

    Topics: Animals; Chromatography, Liquid; Drugs, Chinese Herbal; Emodin; Gallic Acid; Glucosides; Male; Medicine, Chinese Traditional; Models, Biological; Plant Roots; Polygonum; Rats; Rats, Sprague-Dawley; Resveratrol; Spectrometry, Mass, Electrospray Ionization; Stilbenes; Tandem Mass Spectrometry

2013
[Chemical constituents from Pleione bulbocodioides].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2012, Volume: 35, Issue:10

    Topics: Benzaldehydes; Benzyl Alcohols; Biflavonoids; Glucosides; Hydroquinones; Magnetic Resonance Spectroscopy; Molecular Structure; Orchidaceae; Phenols; Rhizome; Stilbenes

2012
[Effects of polydatin on ALT, AST, TNF-alpha, and COX-2 in sepsis model mice].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2013, Volume: 33, Issue:2

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Cyclooxygenase 2; Disease Models, Animal; Glucosides; Liver; Mice; Mice, Inbred Strains; Sepsis; Stilbenes; Tumor Necrosis Factor-alpha

2013
Effects of pre- and post-treatment with plant polyphenols on human keratinocyte responses to solar UV.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2013, Volume: 62, Issue:8

    Topics: Anti-Inflammatory Agents; Cells, Cultured; Glucosides; Humans; Keratinocytes; Nitric Oxide; Peroxides; Peroxynitrous Acid; Phenols; Quercetin; Resveratrol; Stilbenes; Ultraviolet Rays

2013
Simultaneous determination of 5 major bioactive components in hugu capsule by HPLC-DAD.
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2012, Volume: 35, Issue:12

    Topics: Capsules; Chlorogenic Acid; Chromatography, High Pressure Liquid; Coumaric Acids; Drug Combinations; Drugs, Chinese Herbal; Flavanones; Flavonoids; Glucosides; Quality Control; Reproducibility of Results; Stilbenes

2012
A common fungal associate of the spruce bark beetle metabolizes the stilbene defenses of Norway spruce.
    Plant physiology, 2013, Volume: 162, Issue:3

    Topics: Acyltransferases; Adaptation, Physiological; Animals; Ascomycota; Caffeic Acids; Carbon; Coleoptera; Glucosides; Host-Pathogen Interactions; Picea; Plant Bark; Plant Diseases; Stilbenes

2013
Two new dihydrostilbenoid glycosides isolated from the leaves of Litsea coreana and their anti-inflammatory activity.
    Natural product communications, 2013, Volume: 8, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Cells, Cultured; Glucosides; Litsea; Magnetic Resonance Spectroscopy; Mice; Plant Leaves; Stilbenes

2013
Quality assessment of Japanese knotweed (Fallopia japonica) grown on Prince Edward Island as a source of resveratrol.
    Journal of agricultural and food chemistry, 2013, Jul-03, Volume: 61, Issue:26

    Topics: Antioxidants; Emodin; Fallopia japonica; Glucosides; Plant Leaves; Plant Roots; Plant Stems; Plant Weeds; Prince Edward Island; Quality Control; Resveratrol; Stilbenes

2013
Enhancement of polydatin on inward rectifier potassium channel current in rat ventricular myocytes.
    Sheng li xue bao : [Acta physiologica Sinica], 2013, Jun-25, Volume: 65, Issue:3

    Topics: Animals; Anti-Arrhythmia Agents; Glucosides; Myocytes, Cardiac; Patch-Clamp Techniques; Potassium Channels, Inwardly Rectifying; Rats; Stilbenes

2013
3D NMR structure of a complex between the amyloid beta peptide (1-40) and the polyphenol ε-viniferin glucoside: implications in Alzheimer's disease.
    Biochimica et biophysica acta, 2013, Volume: 1830, Issue:11

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Benzofurans; Binding Sites; Cell Line, Tumor; Glucosides; Magnetic Resonance Spectroscopy; Models, Molecular; PC12 Cells; Peptide Fragments; Polyphenols; Protein Conformation; Rats; Stilbenes

2013
Validation of HPLC method for the determination of polydatin in giant knotweed rhizome.
    Yao xue xue bao = Acta pharmaceutica Sinica, 2013, Volume: 48, Issue:4

    Topics: Chromatography, High Pressure Liquid; Drug Stability; Fallopia japonica; Glucosides; Plants, Medicinal; Reproducibility of Results; Rhizome; Sensitivity and Specificity; Stilbenes

2013
Polydatin attenuated food allergy via store-operated calcium channels in mast cell.
    World journal of gastroenterology, 2013, Jul-07, Volume: 19, Issue:25

    Topics: Animals; Calcium; Calcium Channels; Disease Models, Animal; Drugs, Chinese Herbal; Female; Food Hypersensitivity; Glucosides; Histamine; Immunoglobulin E; Interleukin-4; Intestine, Small; Mast Cells; Ovalbumin; Rats; Rats, Inbred BN; Stilbenes

2013
Neuroprotection by tetrahydroxystilbene glucoside in the MPTP mouse model of Parkinson's disease.
    Toxicology letters, 2013, Oct-24, Volume: 222, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apoptosis Regulatory Proteins; Ataxia; Behavior, Animal; Cell Survival; Corpus Striatum; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Dopaminergic Neurons; Glucosides; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Male; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Neuroprotective Agents; Parkinson Disease; Proto-Oncogene Proteins c-akt; Signal Transduction; Stilbenes; Substantia Nigra; Tyrosine 3-Monooxygenase

2013
Highly efficient biotransformation of polydatin to resveratrol by snailase hydrolysis using response surface methodology optimization.
    Molecules (Basel, Switzerland), 2013, Aug-13, Volume: 18, Issue:8

    Topics: Antioxidants; Biotransformation; Glucosides; Humans; Hydrolysis; Resveratrol; Stilbenes; Surface Properties; Temperature; Vitis

2013
Phenolic composition and antioxidant activity in sparkling wines: modulation by the ageing on lees.
    Food chemistry, 2014, Feb-15, Volume: 145

    Topics: Antioxidants; beta-Glucosidase; Caffeic Acids; Coumaric Acids; Food Handling; Gallic Acid; Glucosides; Phenylethyl Alcohol; Polyphenols; Resveratrol; Stilbenes; Wine

2014
Polydatin, a natural precursor of resveratrol, induces cell cycle arrest and differentiation of human colorectal Caco-2 cell.
    Journal of translational medicine, 2013, Oct-20, Volume: 11

    Topics: Antioxidants; Apoptosis; Blotting, Western; Caco-2 Cells; Cell Cycle; Cell Differentiation; Flow Cytometry; Glucosides; Humans; Microscopy, Confocal; Resveratrol; Stilbenes

2013
Membrane permeability-guided identification of neuroprotective components from Polygonum cuspidatun.
    Pharmaceutical biology, 2014, Volume: 52, Issue:3

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Anthraquinones; Blotting, Western; Cell Line, Tumor; Chromatography, High Pressure Liquid; Dialysis; Dose-Response Relationship, Drug; Fallopia japonica; Gene Expression Regulation, Neoplastic; Glucosides; Humans; Liposomes; Neuroblastoma; Neuroprotective Agents; Permeability; Plant Extracts; Receptors, Nicotinic; Stilbenes

2014
TSG (2,3,4' ,5-tetrahydroxystilbene 2-O-β-D-glucoside) suppresses induction of pro-inflammatory factors by attenuating the binding activity of nuclear factor-κB in microglia.
    Journal of neuroinflammation, 2013, Oct-21, Volume: 10

    Topics: Animals; Blotting, Western; Cell Line; Chromatin Immunoprecipitation; Enzyme-Linked Immunosorbent Assay; Glucosides; Mice; Mice, Inbred C57BL; Microglia; NF-kappa B; Rats; Real-Time Polymerase Chain Reaction; Signal Transduction; Stilbenes

2013
Probing the anti-aging role of polydatin in Caenorhabditis elegans on a chip.
    Integrative biology : quantitative biosciences from nano to macro, 2014, Volume: 6, Issue:1

    Topics: Aging; Animals; Animals, Genetically Modified; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Forkhead Transcription Factors; Glucosides; Glutathione Transferase; Insulin; Insulin-Like Growth Factor I; Microfluidics; Oxidative Stress; Real-Time Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Stilbenes; Superoxide Dismutase; Transcription Factors

2014
Resveratrol and piceid metabolites and their fat-reduction effects in zebrafish larvae.
    Zebrafish, 2014, Volume: 11, Issue:1

    Topics: Animals; Chromatography, High Pressure Liquid; Fluorescent Dyes; Glucosides; Larva; Mass Spectrometry; Oxazines; Resveratrol; Stilbenes; Zebrafish

2014
2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside (THSG) attenuates human platelet aggregation, secretion and spreading in vitro.
    Thrombosis research, 2014, Volume: 133, Issue:2

    Topics: Adenosine Triphosphate; Blood Platelets; Fibrinogen; Glucosides; Humans; P-Selectin; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Polygonum; Stilbenes

2014
Tetrahydroxystilbene glucoside attenuates neuroinflammation through the inhibition of microglia activation.
    Oxidative medicine and cellular longevity, 2013, Volume: 2013

    Topics: Animals; Cell Line; Enzyme Activation; Glucosides; Humans; Inflammation; Lipopolysaccharides; Mice; Microglia; NADPH Oxidases; Neurons; Neuroprotective Agents; NF-kappa B; Reactive Oxygen Species; Signal Transduction; Stilbenes

2013
The stilbenes resveratrol, pterostilbene and piceid affect growth and stress resistance in mammalian cells via a mechanism requiring estrogen receptor beta and the induction of Mn-superoxide dismutase.
    Phytochemistry, 2014, Volume: 98

    Topics: Animals; Antioxidants; Cell Line; Cell Proliferation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estrogen Receptor beta; Glucosides; Humans; Mice; Mice, Inbred C57BL; Mice, Knockout; Molecular Structure; Oxidative Stress; Resveratrol; Stilbenes; Structure-Activity Relationship; Superoxide Dismutase

2014
Enzymatic transformation of polydatin to resveratrol by piceid-β-D-glucosidase from Aspergillus oryzae.
    Bioprocess and biosystems engineering, 2014, Volume: 37, Issue:7

    Topics: Aspergillus oryzae; beta-Glucosidase; Biotechnology; Biotransformation; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Fallopia japonica; Glucosides; Hydrogen-Ion Concentration; Resveratrol; Stilbenes; Temperature; Time Factors

2014
Optimized ultrasound-assisted extraction of phenolic compounds from Polygonum cuspidatum.
    Molecules (Basel, Switzerland), 2013, Dec-20, Volume: 19, Issue:1

    Topics: Emodin; Fallopia japonica; Glucosides; Phenols; Plant Extracts; Resveratrol; Solvents; Sound; Stilbenes; Temperature

2013
Inhibitory effect of desoxyrhaponticin and rhaponticin, two natural stilbene glycosides from the Tibetan nutritional food Rheum tanguticum Maxim. ex Balf., on fatty acid synthase and human breast cancer cells.
    Food & function, 2014, Volume: 5, Issue:2

    Topics: Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Down-Regulation; Enzyme Inhibitors; Fatty Acid Synthases; Fatty Acids; Female; Glucosides; Humans; Plant Extracts; Rheum; Stilbenes; Tibet

2014
The effect of 2,3,4',5-tetrahydroxystilbene-2-O-β-D-glucoside on pressure overload-induced cardiac remodeling in rats and its possible mechanism.
    Planta medica, 2014, Volume: 80, Issue:2-3

    Topics: Animals; Blood Pressure; Glucosides; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Phytotherapy; Plant Extracts; Polygonum; Rats; Stilbenes; Transforming Growth Factor beta1; Ventricular Remodeling

2014
Polygonumosides A-D, stilbene derivatives from processed roots of Polygonum multiflorum.
    Journal of natural products, 2014, Feb-28, Volume: 77, Issue:2

    Topics: Drugs, Chinese Herbal; Glucosides; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plant Roots; Polygonum; Stilbenes

2014
Construction of artificial biosynthetic pathways for resveratrol glucoside derivatives.
    Journal of microbiology and biotechnology, 2014, Volume: 24, Issue:5

    Topics: Antioxidants; Bacterial Proteins; Biosynthetic Pathways; Escherichia coli; Gene Order; Genetic Vectors; Glucosides; Resveratrol; Stilbenes

2014
6-carboxydihydroresveratrol 3-O-β-glucopyranoside--a novel natural product from the Cretaceous relict Metasequoia glyptostroboides.
    Fitoterapia, 2014, Volume: 95

    Topics: Biological Assay; Biological Products; Biphenyl Compounds; Cupressaceae; Free Radical Scavengers; Glucosides; Lipoxygenase Inhibitors; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure; Picrates; Plant Leaves; Plants, Medicinal; Stilbenes; Trees

2014
In vitro effects of active components of Polygonum Multiflorum Radix on enzymes involved in the lipid metabolism.
    Journal of ethnopharmacology, 2014, May-14, Volume: 153, Issue:3

    Topics: Cell Line; Cholesterol; Cholesterol 7-alpha-Hydroxylase; Diacylglycerol O-Acyltransferase; Emodin; Fatty Liver; Glucosides; Humans; Hydroxymethylglutaryl CoA Reductases; Plant Roots; Polygonum; Stilbenes; Triglycerides

2014
Protective effect of polydatin against burn-induced lung injury in rats.
    Respiratory care, 2014, Volume: 59, Issue:9

    Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Bronchoalveolar Lavage Fluid; Burns; Capillary Permeability; Caspase 3; Down-Regulation; Glucosides; Interleukin-1beta; Interleukin-6; Leukocyte Count; Lung; Male; Neutrophils; Organ Size; Peroxidase; Pulmonary Edema; Rats; Rats, Sprague-Dawley; Stilbenes; Survival Rate; Tumor Necrosis Factor-alpha

2014
Potential protection of 2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside against staurosporine-induced toxicity on cultured rat hippocampus neurons.
    Neuroscience letters, 2014, Jul-25, Volume: 576

    Topics: Animals; Apoptosis; Caspase 3; Glucosides; Hippocampus; Neurons; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Primary Cell Culture; Protein Precursors; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Rats, Sprague-Dawley; Signal Transduction; Staurosporine; Stilbenes

2014
Fermentation of Smilax china root by Aspergillus usami and Saccharomyces cerevisiae promoted concentration of resveratrol and oxyresveratrol and the free-radical scavenging activity.
    Journal of the science of food and agriculture, 2014, Volume: 94, Issue:9

    Topics: Aspergillus; Benzothiazoles; Fermentation; Free Radical Scavengers; Glucosides; Humans; Plant Extracts; Plant Roots; Resveratrol; Saccharomyces cerevisiae; Smilax; Stilbenes; Sulfonic Acids

2014
Tyrosinase inhibitory activity of a glucosylated hydroxystilbene in mouse melan-a melanocytes.
    Journal of natural products, 2014, Jun-27, Volume: 77, Issue:6

    Topics: Animals; Glucosides; Melanins; Membrane Glycoproteins; Mice; Microscopy, Fluorescence; Molecular Structure; Monophenol Monooxygenase; Oxidoreductases; Stilbenes

2014
[Molecular action mechanism of desoxyrhaponticin and serum albumin characterized by spectroscopy combined with molecular modelling].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2014, Volume: 39, Issue:6

    Topics: Glucosides; Humans; Models, Molecular; Protein Binding; Protein Conformation; Serum Albumin; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Stilbenes; Thermodynamics

2014
Transcriptome profiling and digital gene expression analysis of Fallopia multiflora to discover putative genes involved in the biosynthesis of 2,3,5,4'-tetrahydroxy stilbene-2-O-β-D-glucoside.
    Gene, 2014, Aug-15, Volume: 547, Issue:1

    Topics: Cluster Analysis; Gene Expression Profiling; Genes, Plant; Glucosides; Polygonaceae; Sequence Analysis, RNA; Stilbenes; Transcriptome

2014
Piceid presents antiproliferative effects in intestinal epithelial Caco-2 cells, effects unrelated to resveratrol release.
    Food & function, 2014, Volume: 5, Issue:9

    Topics: Caco-2 Cells; Cell Cycle; Cell Proliferation; Epithelial Cells; Glucosides; Growth Inhibitors; Humans; Intestines; Resveratrol; Stilbenes

2014
Polydatin attenuates cardiac hypertrophy through modulation of cardiac Ca2+ handling and calcineurin-NFAT signaling pathway.
    American journal of physiology. Heart and circulatory physiology, 2014, Sep-01, Volume: 307, Issue:5

    Topics: Active Transport, Cell Nucleus; Animals; Atrial Natriuretic Factor; Calcineurin; Calcium; Calcium Signaling; Cardiomegaly; Cell Nucleus; Cells, Cultured; Glucosides; Mice; Mice, Inbred C57BL; Myocardial Contraction; Myocytes, Cardiac; Myosin Heavy Chains; NFATC Transcription Factors; Phenylephrine; Rats; Rats, Sprague-Dawley; Sarcoplasmic Reticulum; Stilbenes; Ventricular Remodeling

2014
Protective effect of polydatin, a natural precursor of resveratrol, against cisplatin-induced toxicity in rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2014, Volume: 72

    Topics: Animals; Antioxidants; Catalase; Cisplatin; DNA Damage; Erythrocytes; Glucosides; Glutathione; Lipid Peroxidation; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Resveratrol; Stilbenes; Superoxide Dismutase

2014
Inhibitory effects of 2,3,4',5-tetrahydroxystilbene-2-O-β-D-glucoside on angiotensin II-induced proliferation of vascular smooth muscle cells.
    Chinese journal of integrative medicine, 2015, Volume: 21, Issue:3

    Topics: Angiotensin II; Animals; Cell Cycle; Cell Proliferation; Extracellular Signal-Regulated MAP Kinases; Glucosides; Intracellular Space; Male; Mitogen-Activated Protein Kinase Kinases; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphorylation; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins; Rats, Sprague-Dawley; Reactive Oxygen Species; RNA, Messenger; Stilbenes; Superoxide Dismutase

2015
Unambiguous Determination of the Absolute Configuration of Dimeric Stilbene Glucosides from the Rhizomes of Gnetum africanum.
    Journal of natural products, 2014, Aug-22, Volume: 77, Issue:8

    Topics: Benzofurans; Cameroon; Circular Dichroism; Glucosides; Gnetum; Molecular Structure; Neuroprotective Agents; Nuclear Magnetic Resonance, Biomolecular; Rhizome; Stereoisomerism; Stilbenes

2014
Polydatin promotes Nrf2-ARE anti-oxidative pathway through activating Sirt1 to resist AGEs-induced upregulation of fibronetin and transforming growth factor-β1 in rat glomerular messangial cells.
    Molecular and cellular endocrinology, 2015, Jan-05, Volume: 399

    Topics: Animals; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Fibronectins; Gene Silencing; Glucosides; Glycation End Products, Advanced; Mesangial Cells; NF-E2-Related Factor 2; Oxidative Stress; Rats; Rats, Sprague-Dawley; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Response Elements; Sirtuin 1; Stilbenes; Transforming Growth Factor beta1; Up-Regulation

2015
Chemical taxonomy of tree peony species from China based on root cortex metabolic fingerprinting.
    Phytochemistry, 2014, Volume: 107

    Topics: Acetophenones; Chromatography, High Pressure Liquid; DNA Fingerprinting; Drugs, Chinese Herbal; Flavonoids; Glucosides; Molecular Structure; Monoterpenes; Paeonia; Phenols; Phylogeny; Plants, Medicinal; Steroids; Stilbenes; Tannins; Triterpenes

2014
Protective effect of polydatin on learning and memory impairments in neonatal rats with hypoxic‑ischemic brain injury by up‑regulating brain‑derived neurotrophic factor.
    Molecular medicine reports, 2014, Volume: 10, Issue:6

    Topics: Animals; Animals, Newborn; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Glucosides; Hippocampus; Hypoxia-Ischemia, Brain; Learning; Memory; Memory Disorders; Protective Agents; Rats; Rats, Sprague-Dawley; Stilbenes; Up-Regulation

2014
Polydatin improves glucose and lipid metabolism in experimental diabetes through activating the Akt signaling pathway.
    European journal of pharmacology, 2014, Dec-15, Volume: 745

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Drugs, Chinese Herbal; Glucokinase; Glucose; Glucose-6-Phosphatase; Glucosides; Hep G2 Cells; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Lipid Metabolism; Liver; Male; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Receptors, LDL; Signal Transduction; Sterol Regulatory Element Binding Protein 1; Stilbenes

2014
Tetrahydroxystilbene glucoside protects against oxidized LDL-induced endothelial dysfunction via regulating vimentin cytoskeleton and its colocalization with ICAM-1 and VCAM-1.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2014, Volume: 34, Issue:5

    Topics: Apoptosis; Atherosclerosis; Caspase 3; Cells, Cultured; Cytoskeleton; Down-Regulation; Endothelial Cells; Glucosides; Human Umbilical Vein Endothelial Cells; Humans; Intercellular Adhesion Molecule-1; Lipoproteins, LDL; NF-kappa B; Protective Agents; Signal Transduction; Smad Proteins, Receptor-Regulated; Stilbenes; Vascular Cell Adhesion Molecule-1; Vimentin

2014
Polydatin supplementation ameliorates diet-induced development of insulin resistance and hepatic steatosis in rats.
    Molecular medicine reports, 2015, Volume: 11, Issue:1

    Topics: Adiponectin; Animals; Body Weight; Diet; Dietary Supplements; Disease Models, Animal; Fatty Liver; Gene Expression; Glucose Tolerance Test; Glucosides; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Leptin; Liver; Male; Rats; Stilbenes

2015
Effects of tetrahydroxystilbene glucoside on mouse liver cytochrome P450 enzyme expressions.
    Xenobiotica; the fate of foreign compounds in biological systems, 2015, Volume: 45, Issue:4

    Topics: Animals; Body Weight; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Glucosides; Liver; Male; Membrane Proteins; Mice; Organ Size; PPAR alpha; Pregnane X Receptor; Receptors, Aryl Hydrocarbon; Receptors, Steroid; Stilbenes

2015
Pharmacokinetics and bioavailability study of polydatin in rat plasma by using a LC-MS/MS method.
    Pakistan journal of pharmaceutical sciences, 2014, Volume: 27, Issue:6

    Topics: Animals; Biological Availability; Chromatography, High Pressure Liquid; Drug Stability; Glucosides; Male; Rats; Rats, Sprague-Dawley; Stilbenes; Tandem Mass Spectrometry

2014
2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside protects human umbilical vein endothelial cells against lysophosphatidylcholine-induced apoptosis by upregulating superoxide dismutase and glutathione peroxidase.
    IUBMB life, 2014, Volume: 66, Issue:10

    Topics: Apoptosis; Biomarkers; Blotting, Western; Cell Proliferation; Cells, Cultured; Glucosides; Glutathione Peroxidase; Human Umbilical Vein Endothelial Cells; Humans; Lysophosphatidylcholines; Membrane Potential, Mitochondrial; Oxidative Stress; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes; Superoxide Dismutase

2014
Development and validation of a liquid chromatography with mass spectrometry method to determine resveratrol and piceid isomers in beeswax.
    Journal of separation science, 2015, Volume: 38, Issue:2

    Topics: Chromatography, Liquid; Glucosides; Isomerism; Limit of Detection; Mass Spectrometry; Reference Standards; Reproducibility of Results; Resveratrol; Stilbenes; Waxes

2015
Purification and functional characterization of the first stilbene glucoside-specific β-glucosidase isolated from Lactobacillus kimchi.
    Enzyme and microbial technology, 2014, Volume: 67

    Topics: Bacterial Proteins; beta-Glucosidase; Biotransformation; Disaccharides; Glucosides; Industrial Microbiology; Lactobacillus; Resveratrol; Stilbenes; Substrate Specificity

2014
Polydatin prevents hypertrophy in phenylephrine induced neonatal mouse cardiomyocytes and pressure-overload mouse models.
    European journal of pharmacology, 2015, Jan-05, Volume: 746

    Topics: Adrenergic alpha-1 Receptor Agonists; Animals; Animals, Newborn; Atrial Natriuretic Factor; Cardiomegaly; Cardiotonic Agents; Cell Size; Cells, Cultured; Disease Models, Animal; Drugs, Chinese Herbal; Glucosides; Heart Failure; Heart Ventricles; Male; Mice, Inbred C57BL; Oxidative Stress; Phenylephrine; Rats; rho-Associated Kinases; Stilbenes; Ventricular Remodeling

2015
Attempt to synthesize 2,3,5,4'-tetrahydroxystilbene derived from 2,3,5,4'-tetrahydroxystilbene-2-O-β-glucoside (THSG).
    Chemical & pharmaceutical bulletin, 2015, Volume: 63, Issue:2

    Topics: Catalysis; Glucosides; Palladium; Stilbenes

2015
Polydatin prevents angiotensin II-induced cardiac hypertrophy and myocardial superoxide generation.
    Experimental biology and medicine (Maywood, N.J.), 2015, Volume: 240, Issue:10

    Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Body Weight; Cardiomegaly; Cells, Cultured; Glucosides; Male; Myocardium; Myocytes, Cardiac; NADPH Oxidases; Organ Size; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Resveratrol; RNA, Messenger; Signal Transduction; Stilbenes; Superoxides; Ventricular Myosins

2015
[Inhibitory effect of polydatin on expression of toll-like receptor 4 in ischemia-reperfusion injured NRK-52E cells].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2014, Volume: 39, Issue:16

    Topics: Animals; Cell Line; Drugs, Chinese Herbal; Gene Expression; Glucosides; Humans; Rats; Reperfusion Injury; Stilbenes; Toll-Like Receptor 4

2014
Efficacy of antioxidants as a Complementary and Alternative Medicine (CAM) in combination with the chemotherapeutic agent doxorubicin.
    Integrative cancer therapies, 2015, Volume: 14, Issue:2

    Topics: 3T3 Cells; Animals; Antibiotics, Antineoplastic; Antioxidants; Antrodia; Breast Neoplasms; Complementary Therapies; Curcumin; Doxorubicin; Drug Synergism; Female; Glucosides; Humans; MCF-7 Cells; Mice; Plant Extracts; Reactive Oxygen Species; Resveratrol; Stilbenes; Superoxide Dismutase

2015
Hepatotoxic assessment of Polygoni Multiflori Radix extract and toxicokinetic study of stilbene glucoside and anthraquinones in rats.
    Journal of ethnopharmacology, 2015, Mar-13, Volume: 162

    Topics: Animals; Chemical and Drug Induced Liver Injury; Emodin; Glucosides; Liver; Male; Plant Extracts; Plant Roots; Polygonum; Rats, Sprague-Dawley; Stilbenes; Toxicokinetics

2015
Glycyrrhetinic acid and E.resveratroloside act as potential plant derived compounds against dopamine receptor D3 for Parkinson's disease: a pharmacoinformatics study.
    Drug design, development and therapy, 2015, Volume: 9

    Topics: Binding Sites; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Glucosides; Glycyrrhetinic Acid; Humans; Ligands; Models, Molecular; Molecular Docking Simulation; Parkinson Disease; Phytotherapy; Plants; Receptors, Dopamine D3; Stilbenes; Structure-Activity Relationship

2015
Inhibitory Effects of Polydatin on Lipopolysaccharide-Stimulated RAW 264.7 Cells.
    Inflammation, 2015, Volume: 38, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Cell Line; Cell Survival; Cyclooxygenase 2; Dinoprostone; Drugs, Chinese Herbal; Extracellular Signal-Regulated MAP Kinases; Glucosides; Inflammation; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Macrophages; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinases; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; Phosphorylation; RAW 264.7 Cells; RNA, Messenger; Stilbenes; Transcription, Genetic

2015
Tetrahydroxystilbene glucoside improves TNF-α-induced endothelial dysfunction: involvement of TGFβ/Smad pathway and inhibition of vimentin expression.
    The American journal of Chinese medicine, 2015, Volume: 43, Issue:1

    Topics: Active Transport, Cell Nucleus; Apoptosis; Atherosclerosis; Cells, Cultured; Cytoprotection; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Gene Expression Regulation, Developmental; Glucosides; Humans; L-Lactate Dehydrogenase; Polygonum; Signal Transduction; Smad Proteins; Stilbenes; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Umbilical Veins; Vimentin

2015
Tetrahydroxystilbene glucoside extends mouse life span via upregulating neural klotho and downregulating neural insulin or insulin-like growth factor 1.
    Neurobiology of aging, 2015, Volume: 36, Issue:3

    Topics: Aging; Animals; Cells, Cultured; Down-Regulation; Gene Expression Regulation, Developmental; Glucosides; Glucuronidase; Insulin; Insulin-Like Growth Factor I; Klotho Proteins; Longevity; Memory; Mice, Inbred Strains; Models, Animal; Polygonatum; Signal Transduction; Stilbenes; Up-Regulation

2015
Polydatin attenuates ipopolysaccharide-induced acute lung injury in rats.
    International journal of clinical and experimental pathology, 2014, Volume: 7, Issue:12

    Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Apoptosis; Blotting, Western; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Glucosides; In Situ Nick-End Labeling; Inflammation; Lipopolysaccharides; Male; Rats; Rats, Sprague-Dawley; Stilbenes

2014
Authentication of geographical origin and crop system of grape juices by phenolic compounds and antioxidant activity using chemometrics.
    Journal of food science, 2015, Volume: 80, Issue:3

    Topics: Anthocyanins; Beverages; Biphenyl Compounds; Brazil; Europe; Flavonoids; Fruit; Geography; Glucosides; Humans; Organic Agriculture; Oxidation-Reduction; Phenols; Picrates; Plant Extracts; Resveratrol; Stilbenes; Vitis

2015
Resveratrol inhibits enterovirus 71 replication and pro-inflammatory cytokine secretion in rhabdosarcoma cells through blocking IKKs/NF-κB signaling pathway.
    PloS one, 2015, Volume: 10, Issue:2

    Topics: Antiviral Agents; Cytokines; Dose-Response Relationship, Drug; Enterovirus A, Human; Glucosides; I-kappa B Kinase; Inflammation; Interleukin-6; NF-kappa B; Phosphorylation; Resveratrol; Rhabdomyosarcoma; Signal Transduction; Stilbenes; Tumor Necrosis Factor-alpha; Virus Replication

2015
Novel nanoliposomal delivery system for polydatin: preparation, characterization, and in vivo evaluation.
    Drug design, development and therapy, 2015, Volume: 9

    Topics: Administration, Oral; Animals; Drug Delivery Systems; Glucosides; Liposomes; Male; Molecular Structure; Nanoparticles; Particle Size; Rats; Rats, Sprague-Dawley; Stilbenes

2015
[Comparative study on pharmacokinetics and tissue distribution of cis- and trans-2,3,5,4'-Tetrahydroxystilbene-2-O-beta-D-glucosides in mice].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2014, Volume: 37, Issue:9

    Topics: Acetic Acid; Animals; Glucosides; Half-Life; Mice; Stilbenes

2014
Genetic diversity of stilbene metabolism in Vitis sylvestris.
    Journal of experimental botany, 2015, Volume: 66, Issue:11

    Topics: Acyltransferases; Gene Expression Regulation, Plant; Genetic Variation; Genotype; Glucosides; Oomycetes; Phytoalexins; Plant Diseases; Plant Immunity; Plant Leaves; Plant Stomata; Resveratrol; Sesquiterpenes; Stilbenes; Ultraviolet Rays; Vitis

2015
Discovery of the glycogen phosphorylase-modulating activity of a resveratrol glucoside by using a virtual screening protocol optimized for solvation effects.
    Planta medica, 2015, Volume: 81, Issue:6

    Topics: Animals; Biological Products; Glucosides; Glycogen Phosphorylase; Rabbits; Resveratrol; Solubility; Stilbenes; Water

2015
Cardioprotective effect of polydatin on ventricular remodeling after myocardial infarction in coronary artery ligation rats.
    Planta medica, 2015, Volume: 81, Issue:7

    Topics: Aldosterone; Animals; Antioxidants; Captopril; Collagen; Coronary Occlusion; Coronary Vessels; Endothelin-1; Glucosides; Heart Ventricles; Hydroxyproline; Hypertrophy; Male; Myocardial Infarction; Myocardium; Myocytes, Cardiac; Nitric Oxide; Phytotherapy; Plant Extracts; Polygonum; Rats, Sprague-Dawley; Renin-Angiotensin System; Stilbenes; Ventricular Remodeling

2015
Characterization of the Supermolecular Structure of Polydatin/6-O-α-Maltosyl-β-cyclodextrin Inclusion Complex.
    Journal of food science, 2015, Volume: 80, Issue:6

    Topics: alpha-Cyclodextrins; beta-Cyclodextrins; Calorimetry, Differential Scanning; Cyclodextrins; Food Handling; Functional Food; Glucosides; Magnetic Resonance Spectroscopy; Maltose; Molecular Docking Simulation; Molecular Structure; Plants, Medicinal; Polygonum; Solubility; Spectroscopy, Fourier Transform Infrared; Stilbenes; Water

2015
Proliferation of rat cardiac stem cells is induced by 2, 3, 5, 4'-tetrahydroxystilbene-2-O-β-D-glucoside in vitro.
    Life sciences, 2015, Jul-01, Volume: 132

    Topics: Analysis of Variance; Animals; Blotting, Western; Cell Proliferation; Cells, Cultured; DNA Primers; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Gene Expression Profiling; Glucosides; In Vitro Techniques; Myoblasts, Cardiac; Myocardium; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Stem Cell Factor; Stilbenes; Vascular Endothelial Growth Factor A

2015
[Anti-hyperuricemia effect and mechanism of polydatin in mice].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2014, Volume: 49, Issue:12

    Topics: Animals; Disease Models, Animal; Glucosides; Hyperuricemia; Kidney; Mice; Stilbenes; Uric Acid

2014
Polydatin Restores Endothelium-Dependent Relaxation in Rat Aorta Rings Impaired by High Glucose: A Novel Insight into the PPARβ-NO Signaling Pathway.
    PloS one, 2015, Volume: 10, Issue:5

    Topics: Animals; Aorta, Thoracic; Endothelial Cells; Endothelium; Enzyme Activation; Fallopia japonica; Female; Glucose; Glucosides; Hyperglycemia; Male; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Plant Preparations; PPAR-beta; Rats; Rats, Sprague-Dawley; Signal Transduction; Stilbenes; Vasodilation; Vasodilator Agents

2015
Emodin is identified as the active component of ether extracts from Rhizoma Polygoni Cuspidati, for anti-MRSA activity.
    Canadian journal of physiology and pharmacology, 2015, Volume: 93, Issue:6

    Topics: Anti-Bacterial Agents; Cell Membrane; Cell Wall; Drugs, Chinese Herbal; Emodin; Glucosides; Methicillin-Resistant Staphylococcus aureus; Resveratrol; Rhizome; Stilbenes

2015
Comparative studies of polydatin and resveratrol on mutual transformation and antioxidative effect in vivo.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2015, May-15, Volume: 22, Issue:5

    Topics: Administration, Oral; Animals; Antioxidants; Biotransformation; Catalase; Chromatography, High Pressure Liquid; Fallopia japonica; Glucosides; Glutathione; Glutathione Peroxidase; Male; Mice; Myocardium; Oxidative Stress; Rats, Sprague-Dawley; Resveratrol; Rhizome; Stilbenes; Superoxide Dismutase

2015
Anti-oxidant polydatin (piceid) protects against substantia nigral motor degeneration in multiple rodent models of Parkinson's disease.
    Molecular neurodegeneration, 2015, Mar-02, Volume: 10

    Topics: Animals; Behavior, Animal; Disease Models, Animal; Dopaminergic Neurons; Glucosides; Male; Mice, Inbred C57BL; Motor Neurons; Nerve Degeneration; Neuroprotective Agents; Oxidants; Oxidative Stress; Parkinson Disease; Rats, Sprague-Dawley; Stilbenes; Substantia Nigra

2015
Polydatin protects hepatocytes against mitochondrial injury in acute severe hemorrhagic shock via SIRT1-SOD2 pathway.
    Expert opinion on therapeutic targets, 2015, Volume: 19, Issue:7

    Topics: Animals; Cyclosporine; Disease Models, Animal; Glucosides; Hepatocytes; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Resveratrol; Shock, Hemorrhagic; Sirtuin 1; Stilbenes; Superoxide Dismutase

2015
TSG (2,3,5,4'-Tetrahydroxystilbene-2-O- β -D-glucoside) from the Chinese Herb Polygonum multiflorum Increases Life Span and Stress Resistance of Caenorhabditis elegans.
    Oxidative medicine and cellular longevity, 2015, Volume: 2015

    Topics: Animals; Antioxidants; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Drugs, Chinese Herbal; Fallopia multiflora; Free Radical Scavengers; Glucosides; Glutathione Transferase; Heat-Shock Response; Longevity; Mutation; Reactive Oxygen Species; Stilbenes; Stress, Physiological; Superoxide Dismutase

2015
Polydatin: a new therapeutic agent against multiorgan dysfunction.
    The Journal of surgical research, 2015, Volume: 198, Issue:1

    Topics: Animals; Caspase 3; Cytokines; Female; Glucosides; Multiple Organ Failure; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Stilbenes

2015
Activating mitochondrial function and haemoglobin expression with EH-201, an inducer of erythropoietin in neuronal cells, reverses memory impairment.
    British journal of pharmacology, 2015, Volume: 172, Issue:19

    Topics: Animals; Astrocytes; Cells, Cultured; Disease Models, Animal; Erythropoietin; Female; Glucosides; Hemoglobins; Hydrogen Peroxide; Kainic Acid; Male; Memory Disorders; Mice, Inbred C57BL; Mitochondria; Neuroprotective Agents; PC12 Cells; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Rats; Reactive Oxygen Species; Stilbenes; Succinate Dehydrogenase; Transcription Factors

2015
Tetrahydroxy stilbene glucoside improved the behavioral disorders of APP695V717I transgenic mice by inhibiting the expression of Beclin-1 and LC3-II.
    Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, 2015, Volume: 35, Issue:3

    Topics: Alzheimer Disease; Animals; Apoptosis Regulatory Proteins; Beclin-1; Behavior, Animal; Disease Models, Animal; Female; Glucosides; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microtubule-Associated Proteins; Stilbenes

2015
[Effects of polydatin on learning and memory and Cdk5 kinase activity in the hippocampus of rats with chronic alcoholism].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2015, Volume: 31, Issue:2

    Topics: Alcoholism; Animals; Cyclin-Dependent Kinase 5; Drugs, Chinese Herbal; Glucosides; Hippocampus; Learning; Memory; Rats; Stilbenes

2015
Small Molecule Agonists of Cell Adhesion Molecule L1 Mimic L1 Functions In Vivo.
    Molecular neurobiology, 2016, Volume: 53, Issue:7

    Topics: Animals; Astrocytes; Cell Movement; Cell Proliferation; Cell Survival; Cells, Cultured; Duloxetine Hydrochloride; Extracellular Signal-Regulated MAP Kinases; Female; Femoral Nerve; Glucosides; Male; Mice, Inbred C57BL; Microglia; Motor Neurons; Myelin Sheath; Nerve Regeneration; Neural Cell Adhesion Molecule L1; Neuronal Outgrowth; Neurons; Peptides; Phosphorylation; Proteolysis; Small Molecule Libraries; Spinal Cord Injuries; Stilbenes

2016
Multiple Comparisons of Glucokinase Activation Mechanisms of Five Mulberry Bioactive Ingredients in Hepatocyte.
    Journal of agricultural and food chemistry, 2016, Mar-30, Volume: 64, Issue:12

    Topics: 1-Deoxynojirimycin; Adaptor Proteins, Signal Transducing; Anthocyanins; Blood Glucose; Carrier Proteins; Glucokinase; Glucose; Glucosides; Hepatocytes; Liver; Morus; Plant Extracts; Resveratrol; Stilbenes; Up-Regulation

2016
Tetrahydroxystilbene Glucoside Improves Neurotrophic Factors Release in Cultured Astroglia.
    CNS & neurological disorders drug targets, 2016, Volume: 15, Issue:4

    Topics: Animals; Animals, Newborn; Astrocytes; Brain; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Fallopia multiflora; Female; Glucosides; Mitogen-Activated Protein Kinase 3; Nerve Growth Factors; Neuroprotective Agents; Rats; Rats, Wistar; Signal Transduction; Stilbenes

2016
Polydatin Alleviates Small Intestine Injury during Hemorrhagic Shock as a SIRT1 Activator.
    Oxidative medicine and cellular longevity, 2015, Volume: 2015

    Topics: Animals; Apoptosis; Disease Models, Animal; Drugs, Chinese Herbal; Female; Glucosides; Humans; Intestine, Small; Oxidative Stress; Rats; Rats, Sprague-Dawley; Shock, Hemorrhagic; Stilbenes

2015
Ameliorative effect of polydatin on oxidative stress-mediated testicular damage by chronic arsenic exposure in rats.
    Andrologia, 2016, Volume: 48, Issue:5

    Topics: Animals; Antioxidants; Arsenic; Catalase; DNA Damage; Drugs, Chinese Herbal; Glucosides; Glutathione; Lipid Peroxidation; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Sertoli Cells; Sperm Motility; Stilbenes; Superoxide Dismutase; Testis

2016
Properties of a novel polydatin-β-d-glucosidase from Aspergillus niger SK34.002 and its application in enzymatic preparation of resveratrol.
    Journal of the science of food and agriculture, 2016, Volume: 96, Issue:7

    Topics: Amino Acid Sequence; Aspergillus niger; beta-Glucosidase; Biotechnology; Biotransformation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Fungal; Glucosides; Metals; Molecular Sequence Data; Resveratrol; Stilbenes; Substrate Specificity

2016
Analysis of trans-resveratrol and trans-piceid in vegetable foods using high-performance liquid chromatography.
    International journal of food sciences and nutrition, 2015, Volume: 66, Issue:7

    Topics: China; Chromatography, High Pressure Liquid; Diet; Glucosides; Humans; Resveratrol; Stilbenes; Vegetables

2015
Tetrahydroxystilbene glucoside ameliorates memory and movement functions, protects synapses and inhibits α-synuclein aggregation in hippocampus and striatum in aged mice.
    Restorative neurology and neuroscience, 2015, Volume: 33, Issue:4

    Topics: Aging; alpha-Synuclein; Animals; Avoidance Learning; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cerebral Cortex; Corpus Striatum; Female; Glucosides; Hippocampus; Memory; Memory Disorders; Mice, Inbred C57BL; Motor Activity; Movement Disorders; Neuroprotective Agents; Nootropic Agents; Protein Aggregates; Stilbenes; Synapses; Treatment Outcome

2015
Comparison of Polyphenol Profile and Inhibitory Activities Against Oxidation and α-Glucosidase in Mulberry (Genus Morus) Cultivars from China.
    Journal of food science, 2015, Volume: 80, Issue:11

    Topics: alpha-Glucosidases; Anthocyanins; Antioxidants; China; Chlorogenic Acid; Flavonols; Fruit; Glucosides; Humans; Morus; Oxidation-Reduction; Plant Extracts; Polyphenols; Quercetin; Rutin; Species Specificity; Stilbenes; Tandem Mass Spectrometry

2015
Naturally Occurring Stilbenoid TSG Reverses Non-Alcoholic Fatty Liver Diseases via Gut-Liver Axis.
    PloS one, 2015, Volume: 10, Issue:10

    Topics: Animals; Diet, High-Fat; Flow Cytometry; Glucosides; Inflammation; Intestinal Mucosa; Liver; Male; Microbiota; Non-alcoholic Fatty Liver Disease; Rats; Rats, Sprague-Dawley; Signal Transduction; Stilbenes

2015
Protective effects of 2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside in the MPTP-induced mouse model of Parkinson's disease: Involvement of reactive oxygen species-mediated JNK, P38 and mitochondrial pathways.
    European journal of pharmacology, 2015, Nov-15, Volume: 767

    Topics: Animals; Apoptosis Regulatory Proteins; Behavior, Animal; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Glucosides; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Signaling System; Mice; Mitochondria; Neuroprotective Agents; Parkinsonian Disorders; Phosphorylation; Reactive Oxygen Species; Stilbenes; Tyrosine 3-Monooxygenase

2015
Polydatin Inhibits Mitochondrial Dysfunction in the Renal Tubular Epithelial Cells of a Rat Model of Sepsis-Induced Acute Kidney Injury.
    Anesthesia and analgesia, 2015, Volume: 121, Issue:5

    Topics: Acute Kidney Injury; Animals; Disease Models, Animal; Drugs, Chinese Herbal; Epithelial Cells; Glucosides; Kidney Tubules; Membrane Potential, Mitochondrial; Mitochondria; Rats; Rats, Sprague-Dawley; Sepsis; Stilbenes

2015
Protective effects of polydatin on lipopolysaccharide-induced acute lung injury through TLR4-MyD88-NF-κB pathway.
    International immunopharmacology, 2015, Volume: 29, Issue:2

    Topics: Acute Lung Injury; Animals; Bronchoalveolar Lavage Fluid; Cell Line; Cytokines; Glucosides; Leukocyte Count; Lipopolysaccharides; Male; Mice; Mice, Inbred BALB C; Myeloid Differentiation Factor 88; NF-kappa B; Signal Transduction; Stilbenes; Toll-Like Receptor 4

2015
[Protective effects of polydatin on HK-2 cells against oxygen-glucose deprivation/re-oxygenation-induced injury by regulating Sonic hedgehog through PI3K/Akt signaling pathway].
    Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, 2015, Volume: 31, Issue:11

    Topics: Cell Survival; Cells, Cultured; Cytoprotection; Glucosides; Hedgehog Proteins; Humans; Hypoxia; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; Stilbenes

2015
Nephroprotective Effects of Polydatin against Ischemia/Reperfusion Injury: A Role for the PI3K/Akt Signal Pathway.
    Oxidative medicine and cellular longevity, 2015, Volume: 2015

    Topics: Animals; Antioxidants; Cyclooxygenase 2; Disease Models, Animal; Glucosides; Interleukin-1beta; Kidney; Male; Mice; Mice, Inbred BALB C; Nitric Oxide Synthase Type II; Oxidative Stress; Oxidoreductases; Phosphatidylinositol 3-Kinases; Protective Agents; Proto-Oncogene Proteins c-akt; Reperfusion Injury; Signal Transduction; Stilbenes; Tumor Necrosis Factor-alpha; Up-Regulation

2015
[Pharmacokinetics of loganin, ferulic acid and stilbene glucoside in Bushen Tongluo formula in vivo].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2015, Volume: 40, Issue:12

    Topics: Administration, Oral; Animals; Biological Availability; Coumaric Acids; Drugs, Chinese Herbal; Glucosides; Iridoids; Male; Rats; Rats, Sprague-Dawley; Stilbenes

2015
Polydatin Induces Apoptosis and Inhibits Growth of Acute Monocytic Leukemia Cells.
    Journal of biochemical and molecular toxicology, 2016, Volume: 30, Issue:4

    Topics: Apoptosis; bcl-2-Associated X Protein; Cell Line, Tumor; Cell Proliferation; Cyclins; Glucosides; Humans; Leukemia, Monocytic, Acute; Proto-Oncogene Proteins c-bcl-2; S Phase; Stilbenes

2016
Beneficial effects of polydatin on learning and memory in rats with chronic ethanol exposure.
    International journal of clinical and experimental pathology, 2015, Volume: 8, Issue:9

    Topics: Alcohol Drinking; Animals; Behavior, Animal; Cell Survival; Cells, Cultured; Central Nervous System Depressants; Cognition; Cyclin-Dependent Kinase 5; Ethanol; Glucosides; Hippocampus; Male; Maze Learning; Memory; Neurons; Neuroprotective Agents; Rats, Sprague-Dawley; Stilbenes

2015
TSG attenuates LPC-induced endothelial cells inflammatory damage through notch signaling inhibition.
    IUBMB life, 2016, Volume: 68, Issue:1

    Topics: Apoptosis; Basic Helix-Loop-Helix Transcription Factors; C-Reactive Protein; Cell Adhesion; Cell Movement; Cell Survival; Chemokine CCL2; Dipeptides; Gene Knockdown Techniques; Glucosides; Homeodomain Proteins; Human Umbilical Vein Endothelial Cells; Humans; Interleukin-6; Lysophosphatidylcholines; Receptor, Notch1; Signal Transduction; Stilbenes; Transcription Factor HES-1

2016
A study of retention characteristics and quality control of nutraceuticals containing resveratrol and polydatin using fused-core column chromatography.
    Journal of pharmaceutical and biomedical analysis, 2016, Feb-20, Volume: 120

    Topics: Acetonitriles; Chromatography, High Pressure Liquid; Dietary Supplements; Glucosides; Indicators and Reagents; Nitrophenols; Quality Control; Resveratrol; Solutions; Stilbenes

2016
Resveratrol-4‑O-D‑(2'-galloyl)-glucopyranoside exerts an anticancer effect on leukemia cells via inducing apoptosis.
    Molecular medicine reports, 2016, Volume: 13, Issue:3

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspase 9; Cell Line, Tumor; Cell Proliferation; Cytochromes c; Flow Cytometry; Glucosides; Leukemia; Mice, Nude; Proto-Oncogene Proteins c-bcl-2; Resveratrol; Stilbenes; Xenograft Model Antitumor Assays

2016
Polydatin ameliorates lipid and glucose metabolism in type 2 diabetes mellitus by downregulating proprotein convertase subtilisin/kexin type 9 (PCSK9).
    Cardiovascular diabetology, 2016, Feb-01, Volume: 15

    Topics: Animals; Biomarkers; Blood Glucose; Diabetes Mellitus, Type 2; Disease Models, Animal; Down-Regulation; Drugs, Chinese Herbal; Female; Germinal Center Kinases; Glucosides; Hep G2 Cells; Hepatocytes; Humans; Hydrogen Bonding; Hypoglycemic Agents; Insulin Resistance; Lipid Metabolism; Lipids; Liver; Mice; Mice, Inbred C57BL; Molecular Docking Simulation; Palmitic Acid; Proprotein Convertase 9; Proprotein Convertases; Protein Binding; Protein Conformation; Protein Serine-Threonine Kinases; Receptors, LDL; RNA Interference; Serine Endopeptidases; Stilbenes; Time Factors; Transfection

2016
Polydatin Attenuates H2O2-Induced Oxidative Stress via PKC Pathway.
    Oxidative medicine and cellular longevity, 2016, Volume: 2016

    Topics: Apoptosis; Drugs, Chinese Herbal; Glucosides; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen Peroxide; Oxidative Stress; Protein Kinase C; Signal Transduction; Stilbenes

2016
Polydatin-induced cell apoptosis and cell cycle arrest are potentiated by Janus kinase 2 inhibition in leukemia cells.
    Molecular medicine reports, 2016, Volume: 13, Issue:4

    Topics: Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cyclin B1; Cyclin D1; Glucosides; Humans; Janus Kinase 2; Leukemia; Membrane Potential, Mitochondrial; Mitochondria; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; STAT3 Transcription Factor; Stilbenes

2016
Polydatin attenuates AGEs-induced upregulation of fibronectin and ICAM-1 in rat glomerular mesangial cells and db/db diabetic mice kidneys by inhibiting the activation of the SphK1-S1P signaling pathway.
    Molecular and cellular endocrinology, 2016, May-15, Volume: 427

    Topics: Animals; Cells, Cultured; Diabetes Mellitus, Experimental; Drugs, Chinese Herbal; Female; Fibronectins; Glomerular Mesangium; Glucosides; Glycation End Products, Advanced; Humans; Hypoglycemic Agents; Intercellular Adhesion Molecule-1; Lysophospholipids; Male; Mice; Phosphotransferases (Alcohol Group Acceptor); Rats; Rats, Sprague-Dawley; Signal Transduction; Sphingosine; Stilbenes; Up-Regulation

2016
Integrated In Silico-In Vitro Discovery of Lung Cancer-related Tumor Pyruvate Kinase M2 (PKM2) Inhibitors.
    Medicinal chemistry (Shariqah (United Arab Emirates)), 2016, Volume: 12, Issue:7

    Topics: Carrier Proteins; Catalytic Domain; Computer Simulation; Drug Discovery; Enzyme Assays; Glucosides; Hematoxylin; Humans; Indoprofen; Lung Neoplasms; Membrane Proteins; Molecular Docking Simulation; Molecular Dynamics Simulation; Nalidixic Acid; Protein Kinase Inhibitors; Pyruvate Kinase; Stilbenes; Thyroid Hormone-Binding Proteins; Thyroid Hormones

2016
Polydatin Protecting Kidneys against Hemorrhagic Shock-Induced Mitochondrial Dysfunction via SIRT1 Activation and p53 Deacetylation.
    Oxidative medicine and cellular longevity, 2016, Volume: 2016

    Topics: Animals; Blotting, Western; Carbazoles; Cell Hypoxia; Cells, Cultured; Female; Glucosides; Immunohistochemistry; Kidney; Male; Membrane Potential, Mitochondrial; Mitochondria; Oxygen; Protective Agents; Rats; Rats, Sprague-Dawley; Shock, Hemorrhagic; Sirtuin 1; Stilbenes; Tumor Suppressor Protein p53

2016
Polydatin ameliorates injury to the small intestine induced by hemorrhagic shock via SIRT3 activation-mediated mitochondrial protection.
    Expert opinion on therapeutic targets, 2016, Volume: 20, Issue:6

    Topics: Animals; Disease Models, Animal; Female; Glucosides; Hydrogen Peroxide; Intestine, Small; Male; Mitochondria; Oxidative Stress; Rats; Rats, Sprague-Dawley; Resveratrol; Shock, Hemorrhagic; Signal Transduction; Sirtuins; Stilbenes; Superoxide Dismutase

2016
[Effect and mechanism of polydatin on diabetic myocardial hypertrophy in mice].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2015, Volume: 40, Issue:21

    Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Drugs, Chinese Herbal; Glucosides; Humans; Hypertrophy; Insulin; Male; Mice; NF-kappa B; Signal Transduction; Stilbenes

2015
Polydatin inhibits the oxidative stress-induced proliferation of vascular smooth muscle cells by activating the eNOS/SIRT1 pathway.
    International journal of molecular medicine, 2016, Volume: 37, Issue:6

    Topics: Animals; Antioxidants; Aorta, Thoracic; Carbazoles; CDC2 Protein Kinase; Cell Cycle; Cell Proliferation; Cyclin B1; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation; Glucosides; Hydrogen Peroxide; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Oxidative Stress; Primary Cell Culture; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Sirtuin 1; Stilbenes

2016
A new co-micronized composite containing palmitoylethanolamide and polydatin shows superior oral efficacy compared to their association in a rat paw model of carrageenan-induced inflammation.
    European journal of pharmacology, 2016, 07-05, Volume: 782

    Topics: Active Transport, Cell Nucleus; Administration, Oral; Amides; Animals; Carrageenan; Cell Line, Tumor; Cell Nucleus; Cyclooxygenase 2; Cytokines; Disease Models, Animal; Drug Compounding; Drug Interactions; Edema; Ethanolamines; Gene Expression Regulation, Enzymologic; Glucosides; Hyperalgesia; Inflammation; Male; Neutrophil Infiltration; NF-KappaB Inhibitor alpha; Nitric Oxide Synthase Type II; Palmitic Acids; Proteolysis; Rats; Rats, Sprague-Dawley; Stilbenes; Superoxide Dismutase; Transcription Factor RelA; Tyrosine

2016
Efficient Regioselective Synthesis of the Crotonyl Polydatin Prodrug by Thermomyces lanuginosus Lipase: a Kinetics Study in Eco-friendly 2-Methyltetrahydrofuran.
    Applied biochemistry and biotechnology, 2016, Volume: 179, Issue:6

    Topics: Acylation; Catalysis; Eurotiales; Furans; Glucosides; Kinetics; Lipase; Prodrugs; Solvents; Stereoisomerism; Stilbenes; Substrate Specificity

2016
New Procedure to Obtain Polyphenol-Enriched Grapes Based on the Use of Chemical Elicitors.
    Plant foods for human nutrition (Dordrecht, Netherlands), 2016, Volume: 71, Issue:3

    Topics: Acetates; Antioxidants; Cyclopentanes; Ethanol; Flavonoids; Food Handling; Fruit; Glucosides; Oxylipins; Polyphenols; Quercetin; Resveratrol; Rutin; Stilbenes; Vitis

2016
[Polyketone Reaction in Biosynthetic Pathways of 2, 3, 5, 4'-Tetrahydroxy Stilhene-2-O-β-D-glucoside in Polygonum multiflorum by Biocatalysis].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2015, Volume: 38, Issue:10

    Topics: Acyltransferases; Biocatalysis; Biosynthetic Pathways; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Fallopia multiflora; Glucosides; Mass Spectrometry; Resveratrol; Stilbenes

2015
Chronic administration tetrahydroxystilbene glucoside promotes hippocampal memory and synaptic plasticity and activates ERKs, CaMKII and SIRT1/miR-134 in vivo.
    Journal of ethnopharmacology, 2016, Aug-22, Volume: 190

    Topics: Animals; Behavior, Animal; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Dendritic Spines; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Fear; Glucosides; Hippocampus; Memory; Mice, Inbred C57BL; MicroRNAs; Neuronal Plasticity; Nootropic Agents; Phosphorylation; Recognition, Psychology; Signal Transduction; Sirtuin 1; Stilbenes; Time Factors

2016
2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside suppresses human colorectal cancer cell metastasis through inhibiting NF-κB activation.
    International journal of oncology, 2016, Volume: 49, Issue:2

    Topics: Cell Movement; Colorectal Neoplasms; Glucosides; HT29 Cells; Humans; Neoplasm Metastasis; NF-kappa B; Signal Transduction; Stilbenes

2016
LC-MS Guided Isolation of Bioactive Principles from Iris hookeriana and Bioevaluation of Isolates for Antimicrobial and Antioxidant Activities.
    Drug research, 2016, Volume: 66, Issue:8

    Topics: Anti-Bacterial Agents; Antioxidants; Chromatography, Liquid; Flavonols; Glucosides; Iris Plant; Isoflavones; Microbial Sensitivity Tests; Plant Extracts; Resveratrol; Spectrometry, Mass, Electrospray Ionization; Stilbenes

2016
[Effect of polydatin on miR-214 expression and liver function in ApoE-/- mice].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2016, Volume: 36, Issue:6

    Topics: Animals; Apolipoproteins E; Atherosclerosis; Blood Glucose; Diet, High-Fat; Disease Models, Animal; Drugs, Chinese Herbal; Glucosides; Lipids; Liver; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Mice, Knockout; MicroRNAs; Stilbenes; Superoxide Dismutase

2016
[Effect of Polydatin on Epithelial-Mesenchymal Transition of Human Alveolar Epithelium A549 Cells Induced by TGF-β1].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2016, Volume: 36, Issue:4

    Topics: Antigens, CD; Cadherins; Cell Line; Epithelial Cells; Epithelial-Mesenchymal Transition; Glucosides; Humans; Stilbenes; Transforming Growth Factor beta1; Vimentin

2016
Polydatin post-treatment alleviates myocardial ischaemia/reperfusion injury by promoting autophagic flux.
    Clinical science (London, England : 1979), 2016, 09-01, Volume: 130, Issue:18

    Topics: Animals; Apoptosis; Autophagy; Glucosides; Humans; Male; Mice; Mice, Inbred C57BL; Myocardial Reperfusion Injury; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Stilbenes

2016
Cardiac stem cell transplantation with 2,3,5,4'-tetrahydroxystilbehe-2-O-β-d-glucoside improves cardiac function in rat myocardial infarction model.
    Life sciences, 2016, Aug-01, Volume: 158

    Topics: Animals; Disease Models, Animal; Glucosides; Heart Rate; Male; Myocardial Infarction; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; Stem Cell Transplantation; Stilbenes

2016
Polydatin possesses notable anti‑osteoporotic activity via regulation of OPG, RANKL and β‑catenin.
    Molecular medicine reports, 2016, Volume: 14, Issue:2

    Topics: Alkaline Phosphatase; Animals; beta Catenin; Biomarkers; Body Weight; Bone and Bones; Calcium; Cell Line; Disease Models, Animal; Female; Gene Expression Regulation; Glucosides; Mice; Osteoporosis; Osteoprotegerin; Ovariectomy; RANK Ligand; Stilbenes

2016
[Microdevice for the investigation of high-glucose induced lifespan and the protective effect of polydatin in C. elegans].
    Se pu = Chinese journal of chromatography, 2016, Volume: 34, Issue:2

    Topics: Animals; Caenorhabditis elegans; Glucose; Glucosides; Lab-On-A-Chip Devices; Longevity; Oxidative Stress; Stilbenes

2016
Arginase Inhibitor 2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-Glucoside Activates Endothelial Nitric Oxide Synthase and Improves Vascular Function.
    Planta medica, 2017, Volume: 83, Issue:3-04

    Topics: Acetylcholine; Animals; Aorta; Apolipoproteins E; Arginase; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Glucosides; Human Umbilical Vein Endothelial Cells; Humans; Male; Mice; Mice, Inbred C57BL; Nitric Oxide; Nitric Oxide Synthase Type III; Nitroprusside; Phenylephrine; Reactive Oxygen Species; Stilbenes; Superoxides; Vasoconstriction

2017
[Influence of metal ions on stability of 2,3,5,4'-tetrahydroxy stilbene-2-O-β-D-glucoside contained in Polygoni Multiflori Radix].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2016, Volume: 51, Issue:1

    Topics: Drugs, Chinese Herbal; Glucosides; Ions; Metals; Plant Roots; Polygonaceae; Stilbenes

2016
Polydatin induces bone marrow stromal cells migration by activation of ERK1/2.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2016, Volume: 82

    Topics: Animals; Cell Movement; Cell Shape; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Glucosides; JNK Mitogen-Activated Protein Kinases; Male; Mesenchymal Stem Cells; Phosphorylation; Rats, Sprague-Dawley; Stilbenes

2016
Polydatin ameliorates renal ischemia/reperfusion injury by decreasing apoptosis and oxidative stress through activating sonic hedgehog signaling pathway.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2016, Volume: 96

    Topics: Animals; Antioxidants; Apoptosis; Blotting, Western; Cell Proliferation; Cells, Cultured; Drugs, Chinese Herbal; Gene Expression Regulation; Glucosides; Hedgehog Proteins; Male; Mice; Mice, Inbred BALB C; Oxidative Stress; Proto-Oncogene Proteins c-akt; Real-Time Polymerase Chain Reaction; Reperfusion Injury; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes

2016
Bioconversion of piceid to resveratrol by selected probiotic cell extracts.
    Bioprocess and biosystems engineering, 2016, Volume: 39, Issue:12

    Topics: Glucosides; Gram-Positive Bacteria; Resveratrol; Stilbenes

2016
2,3,5,4'-Tetrahydroxystilbene-2-O-β-glucoside Isolated from Polygoni Multiflori Ameliorates the Development of Periodontitis.
    Mediators of inflammation, 2016, Volume: 2016

    Topics: Adult; Animals; Cells, Cultured; Drugs, Chinese Herbal; Female; Fibroblasts; Gingiva; Glucosides; Humans; Male; Periodontitis; Polygonaceae; Rats; Rats, Sprague-Dawley; Stilbenes; Young Adult

2016
In Planta Localization of Stilbenes within Picea abies Phloem.
    Plant physiology, 2016, Volume: 172, Issue:2

    Topics: Freeze Drying; Gas Chromatography-Mass Spectrometry; Glucosides; Imaging, Three-Dimensional; Microscopy, Electron, Scanning; Phloem; Picea; Spectrometry, Mass, Secondary Ion; Stilbenes; Water; X-Ray Microtomography

2016
The inhibition of macrophage foam cell formation by tetrahydroxystilbene glucoside is driven by suppressing vimentin cytoskeleton.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2016, Volume: 83

    Topics: Apoptosis; Blotting, Western; Caspase 3; Cell Differentiation; Cell Nucleus; Cytoskeleton; DNA Fragmentation; Enzyme Activation; Foam Cells; Glucosides; Humans; Intercellular Adhesion Molecule-1; Lipoproteins, LDL; Signal Transduction; Smad Proteins; Stilbenes; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta1; U937 Cells; Vimentin

2016
PPAR-γ is involved in the protective effect of 2,3,4',5-tetrahydroxystilbene-2-O-beta-D-glucoside against cardiac fibrosis in pressure-overloaded rats.
    European journal of pharmacology, 2016, Nov-15, Volume: 791

    Topics: Angiotensin II; Animals; Blood Pressure; Cardiotonic Agents; Cell Differentiation; Cell Proliferation; Collagen Type I; Collagen Type III; Fibroblasts; Fibronectins; Fibrosis; Gene Expression Regulation; Glucosides; Heart; Male; Myocardium; Plasminogen Activator Inhibitor 1; PPAR gamma; Pressure; Rats; Stilbenes

2016
Stilbene biosynthesis in the needles of spruce Picea jezoensis.
    Phytochemistry, 2016, Volume: 131

    Topics: Acyltransferases; Glucosides; Phenols; Picea; Plant Bark; Plant Roots; Resveratrol; Stilbenes

2016
Polydatin protects cardiomyocytes against myocardial infarction injury by activating Sirt3.
    Biochimica et biophysica acta. Molecular basis of disease, 2017, Volume: 1863, Issue:8

    Topics: Animals; Apoptosis; Disease Models, Animal; Glucosides; Mice; Mice, Knockout; Mitochondria, Heart; Myocardial Infarction; Myocytes, Cardiac; Organelle Biogenesis; Sirtuin 3; Stilbenes

2017
2,3,4',5-tetrahydroxystilbene-2-O-β-d-glucoside exerts anti-inflammatory effects on lipopolysaccharide-stimulated microglia by inhibiting NF-κB and activating AMPK/Nrf2 pathways.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2016, Volume: 97

    Topics: AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents; Apoptosis; Blotting, Western; Cell Proliferation; Cells, Cultured; Cytokines; Glucosides; Inflammation; Lipopolysaccharides; Mice; Mice, Inbred ICR; Microglia; NF-E2-Related Factor 2; NF-kappa B; Nitric Oxide; Phosphorylation; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Stilbenes

2016
Polydatin attenuates d-galactose-induced liver and brain damage through its anti-oxidative, anti-inflammatory and anti-apoptotic effects in mice.
    Food & function, 2016, Nov-09, Volume: 7, Issue:11

    Topics: Aging; Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Brain Diseases; Chemical and Drug Induced Liver Injury; Cytokines; Dose-Response Relationship, Drug; Galactose; Glucosides; Liver; Malondialdehyde; Mice; Molecular Structure; Oxidative Stress; Stilbenes

2016
2,3,5,4'-Tetrahydroxystilbene-2-O-β-d-glucoside exerted protective effects on diabetic nephropathy in mice with hyperglycemia induced by streptozotocin.
    Food & function, 2016, Nov-09, Volume: 7, Issue:11

    Topics: Albuminuria; Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Gene Expression Regulation; Glucosides; Kidney; Male; Mice; Mice, Inbred C57BL; RNA, Messenger; Stilbenes

2016
Tetrahydroxystilbene Glucoside Inhibits Excessive Autophagy and Improves Microvascular Endothelial Dysfunction in Prehypertensive Spontaneously Hypertensive Rats.
    The American journal of Chinese medicine, 2016, Volume: 44, Issue:7

    Topics: Animals; Autophagy; Depression, Chemical; Endothelial Cells; Endothelium, Vascular; Fallopia multiflora; Glucosides; Humans; Hypertension; In Vitro Techniques; Male; Microvessels; Phytotherapy; Proto-Oncogene Proteins c-akt; Rats, Inbred SHR; Rats, Inbred WKY; Signal Transduction; Stilbenes; TOR Serine-Threonine Kinases; Vasodilator Agents

2016
Comparison of Regulation Mechanisms of Five Mulberry Ingredients on Insulin Secretion under Oxidative Stress.
    Journal of agricultural and food chemistry, 2016, Nov-23, Volume: 64, Issue:46

    Topics: Animals; Anthocyanins; Apoptosis; Cell Line; Glucokinase; Glucosides; Homeodomain Proteins; Insulin; Insulin-Secreting Cells; Mice; Morus; Oxidative Stress; Paclitaxel; Plant Extracts; Resveratrol; Signal Transduction; Stilbenes; Trans-Activators

2016
Anti-inflammatory protection afforded by cyanidin-3-glucoside and resveratrol in human intestinal cells via Nrf2 and PPAR-γ: Comparison with 5-aminosalicylic acid.
    Chemico-biological interactions, 2016, Dec-25, Volume: 260

    Topics: Anthocyanins; Anti-Inflammatory Agents; Catalysis; Cell Nucleus; Cytokines; Cytoprotection; Gene Expression Regulation; Glucosides; Glutathione Disulfide; Heme Oxygenase-1; HT29 Cells; Humans; Intestines; Intracellular Space; Mesalamine; NF-E2-Related Factor 2; PPAR gamma; Protein Subunits; Resveratrol; RNA, Messenger; Stilbenes

2016
Effective treatment of polydatin weakens the symptoms of collagen-induced arthritis in mice through its anti-oxidative and anti-inflammatory effects and the activation of MMP-9.
    Molecular medicine reports, 2016, Volume: 14, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Arthritis, Experimental; Arthritis, Rheumatoid; bcl-2-Associated X Protein; Biomarkers; Caspase 3; Caspase 9; Disease Models, Animal; Glucosides; Glutathione; Male; Malondialdehyde; Matrix Metalloproteinase 9; Mice; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Stilbenes; Superoxide Dismutase

2016
Neuroprotective effects of polydatin against mitochondrial-dependent apoptosis in the rat cerebral cortex following ischemia/reperfusion injury.
    Molecular medicine reports, 2016, Volume: 14, Issue:6

    Topics: Adenosine Triphosphate; Animals; Apoptosis; bcl-2-Associated X Protein; Biomarkers; Brain Ischemia; Cerebral Cortex; Cytochromes c; Disease Models, Animal; Glucosides; Male; Membrane Potential, Mitochondrial; Mitochondria; Neurons; Neuroprotective Agents; Proto-Oncogene Proteins c-bcl-2; Rats; Reactive Oxygen Species; Reperfusion Injury; Signal Transduction; Stilbenes

2016
2,3,5,4'-Tetrahydroxystilbene-2-O-
    Oxidative medicine and cellular longevity, 2016, Volume: 2016

    Topics: Animals; Glucosides; Glucuronidase; Klotho Proteins; Longevity; Male; Rats; Rats, Wistar; Stilbenes

2016
a-Glucosidase inhibitors extracted from the roots of Polygonum multiflorum Thunb.
    Fitoterapia, 2017, Volume: 117

    Topics: Enzyme Inhibitors; Fallopia multiflora; Glucosidases; Glucosides; Glycosides; Molecular Structure; Plant Extracts; Plant Roots; Stilbenes

2017
Polydatin ameliorates Staphylococcus aureus-induced mastitis in mice via inhibiting TLR2-mediated activation of the p38 MAPK/NF-κB pathway.
    Acta pharmacologica Sinica, 2017, Volume: 38, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Cell Survival; Cytokines; Dexamethasone; Dose-Response Relationship, Drug; Down-Regulation; Female; Glucosides; Inflammation Mediators; MAP Kinase Signaling System; Mastitis; Mice; Neutrophil Infiltration; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Peroxidase; Staphylococcus aureus; Stilbenes; Toll-Like Receptor 2

2017
Synergistic effects of polydatin and vitamin C in inhibiting cardiotoxicity induced by doxorubicin in rats.
    Fundamental & clinical pharmacology, 2017, Volume: 31, Issue:3

    Topics: AMP-Activated Protein Kinases; Animals; Antioxidants; Arterial Pressure; Ascorbic Acid; Cardiotoxicity; Doxorubicin; Drug Synergism; Glucosides; Glutathione; Glutathione Peroxidase; Heart Rate; Male; Malondialdehyde; Myocardium; Oxidative Stress; PPAR gamma; Rats; Rats, Sprague-Dawley; Stilbenes; Superoxide Dismutase

2017
2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-Glucoside Attenuates Ischemia/Reperfusion-Induced Brain Injury in Rats by Promoting Angiogenesis.
    Planta medica, 2017, Volume: 83, Issue:8

    Topics: Angiogenesis Inducing Agents; Angiotensin I; Animals; Blotting, Western; Brain Injuries; Brain Ischemia; Fallopia multiflora; Glucosides; Infarction, Middle Cerebral Artery; Male; Neovascularization, Physiologic; Neuroprotective Agents; Platelet Endothelial Cell Adhesion Molecule-1; Rats; Rats, Sprague-Dawley; Receptor, TIE-2; Reperfusion Injury; Stilbenes; Stroke; Vascular Endothelial Growth Factor A

2017
Neuroprotective effects of 2,3,5,4'-tetrahydoxystilbene-2-O-β-D-glucoside from Polygonum multiflorum against glutamate-induced oxidative toxicity in HT22 cells.
    Journal of ethnopharmacology, 2017, Jan-04, Volume: 195

    Topics: Animals; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Fallopia multiflora; Glucosides; Glutamic Acid; Hippocampus; Membrane Potential, Mitochondrial; Mice; Mitochondria; Neurons; Neuroprotective Agents; Oxidative Stress; Phytotherapy; Plant Extracts; Plants, Medicinal; Reactive Oxygen Species; Stilbenes; Voltage-Dependent Anion Channel 1

2017
Enhanced Stilbene Production and Excretion in Vitis vinifera cv Pinot Noir Hairy Root Cultures.
    Molecules (Basel, Switzerland), 2016, Dec-10, Volume: 21, Issue:12

    Topics: Acetates; Benzofurans; beta-Cyclodextrins; Cyclopentanes; Glucosides; Oxylipins; Plant Roots; Resorcinols; Resveratrol; Stilbenes; Vitis

2016
Highly regioselective hydroxylation of polydatin, a resveratrol glucoside, for one-step synthesis of astringin, a piceatannol glucoside, by P450 BM3.
    Enzyme and microbial technology, 2017, Volume: 97

    Topics: Amino Acid Substitution; Bacillus megaterium; Bacterial Proteins; Biocatalysis; Biotechnology; Cytochrome P-450 Enzyme System; Glucosides; Hydroxylation; Kinetics; Mutagenesis, Site-Directed; NADPH-Ferrihemoprotein Reductase; Protein Engineering; Stilbenes

2017
Mechanism of 2,3,4',5-Tetrahydroxystilbene 2-O-β-D-Glucoside-Induced Upregulation of Glutamate Transporter 1 Protein Expression in Mouse Primary Astrocytes.
    Pharmacology, 2017, Volume: 99, Issue:3-4

    Topics: Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Excitatory Amino Acid Transporter 2; Gene Expression Regulation; Glucosides; Mice; Mice, Inbred C57BL; Stilbenes; Up-Regulation

2017
Anti-diabetic activities of cis- and trans-2,3,5,4'-tetrahydroxystilbene 2-O-β-glucopyranoside from Polygonum multiflorum.
    Molecular nutrition & food research, 2017, Volume: 61, Issue:8

    Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Enzyme Inhibitors; Fallopia multiflora; Glucosides; Hep G2 Cells; Humans; Hypoglycemic Agents; Insulin Resistance; Male; Phosphoenolpyruvate Carboxykinase (ATP); Stilbenes

2017
RSM and ANN modeling-based optimization approach for the development of ultrasound-assisted liposome encapsulation of piceid.
    Ultrasonics sonochemistry, 2017, Volume: 36

    Topics: Capsules; Glucosides; Liposomes; Neural Networks, Computer; Particle Size; Stilbenes; Ultrasonic Waves

2017
2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-glucoside protects murine hearts against ischemia/reperfusion injury by activating Notch1/Hes1 signaling and attenuating endoplasmic reticulum stress.
    Acta pharmacologica Sinica, 2017, Volume: 38, Issue:3

    Topics: Animals; Apoptosis; Cardiotonic Agents; Cell Line; Endoplasmic Reticulum Stress; Glucosides; Male; Mice, Inbred C57BL; Myoblasts, Cardiac; Myocardial Reperfusion Injury; Rats; Receptor, Notch1; Signal Transduction; Stilbenes; Transcription Factor HES-1

2017
Chemical Composition Analysis, Sensory, and Feasibility Study of Tree Peony Seed.
    Journal of food science, 2017, Volume: 82, Issue:2

    Topics: alpha-Linolenic Acid; Antioxidants; Chromans; Feasibility Studies; Food Analysis; gamma-Tocopherol; Glucosides; Linseed Oil; Monoterpenes; Nutritive Value; Oxidation-Reduction; Paeonia; Phenols; Resveratrol; Seeds; Species Specificity; Stilbenes; Trees; Vitamin E

2017
Polydatin improves the developmental competence of bovine embryos in vitro via induction of sirtuin 1 (Sirt1).
    Reproduction, fertility, and development, 2017, Volume: 29, Issue:10

    Topics: Animals; Apoptosis; Cattle; Embryo Culture Techniques; Embryonic Development; Glucosides; Oxidative Stress; Reactive Oxygen Species; Sirtuin 1; Stilbenes

2017
[Lipid-lowering effect of seven traditional Chinese medicine monomers in zebrafish system].
    Sheng li xue bao : [Acta physiologica Sinica], 2017, Feb-25, Volume: 69, Issue:1

    Topics: Animals; Anthraquinones; Diet, High-Fat; Fatty Alcohols; Glucosides; Hyperlipidemias; Hypolipidemic Agents; Larva; Lipids; Medicine, Chinese Traditional; Oleanolic Acid; Shikimic Acid; Stigmasterol; Stilbenes; Vanillic Acid; Zebrafish

2017
Polydatin inhibits cell proliferation and induces apoptosis in laryngeal cancer and HeLa cells via suppression of the PDGF/AKT signaling pathway.
    Journal of biochemical and molecular toxicology, 2017, Volume: 31, Issue:7

    Topics: Animals; Cell Proliferation; Fallopia japonica; Female; Glucosides; HeLa Cells; Humans; Laryngeal Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-akt; Signal Transduction; Stilbenes; Xenograft Model Antitumor Assays

2017
Polydatin promotes Nrf2-ARE anti-oxidative pathway through activating CKIP-1 to resist HG-induced up-regulation of FN and ICAM-1 in GMCs and diabetic mice kidneys.
    Free radical biology & medicine, 2017, Volume: 106

    Topics: Animals; Antioxidants; Carboxylic Ester Hydrolases; Carrier Proteins; Diabetic Nephropathies; Fibronectins; Gene Expression Regulation; Glucose; Glucosides; Humans; Hydrogen Peroxide; Intercellular Adhesion Molecule-1; Kelch-Like ECH-Associated Protein 1; Mesangial Cells; Mice; Mice, Inbred NOD; NF-E2-Related Factor 2; Signal Transduction; Stilbenes; Superoxides

2017
SIRT1 is required for mitochondrial biogenesis reprogramming in hypoxic human pulmonary arteriolar smooth muscle cells.
    International journal of molecular medicine, 2017, Volume: 39, Issue:5

    Topics: Biomarkers; DNA-Binding Proteins; Gene Expression; Gene Knockdown Techniques; Glucosides; Humans; Hypoxia; Mitochondria, Muscle; Mitochondrial Proteins; Models, Biological; Myocytes, Smooth Muscle; Organelle Biogenesis; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Pulmonary Artery; Sirtuin 1; Sirtuin 3; Stilbenes; Transcription Factors

2017
Short-step syntheses of naturally occurring polyoxygenated aromatics based on site-selective transformation.
    Bioscience, biotechnology, and biochemistry, 2017, Volume: 81, Issue:7

    Topics: Acetylation; Chemistry Techniques, Synthetic; Flavanones; Flavonoids; Glucosides; Humans; Molecular Structure; Stereoisomerism; Stilbenes

2017
Root biomass and exudates link plant diversity with soil bacterial and fungal biomass.
    Scientific reports, 2017, 04-04, Volume: 7

    Topics: Bacteria; Benzaldehydes; Biodiversity; Biomass; Carboxylic Acids; Fungi; Glucosides; Microbial Consortia; Plant Roots; Poaceae; Soil; Soil Microbiology; Stilbenes; Symbiosis

2017
Polydatin impairs mitochondria fitness and ameliorates podocyte injury by suppressing Drp1 expression.
    Journal of cellular physiology, 2017, Volume: 232, Issue:10

    Topics: Animals; Apoptosis; Blood Glucose; Cell Line; Cytoprotection; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Models, Animal; Down-Regulation; Dynamins; Glucosides; Mice, Inbred C57BL; Mitochondria; Mitochondrial Dynamics; Podocytes; Reactive Oxygen Species; RNA Interference; Signal Transduction; Stilbenes; Transfection

2017
Polydatin attenuates potassium oxonate-induced hyperuricemia and kidney inflammation by inhibiting NF-κB/NLRP3 inflammasome activation via the AMPK/SIRT1 pathway.
    Food & function, 2017, May-24, Volume: 8, Issue:5

    Topics: AMP-Activated Protein Kinases; Animals; Glucosides; Humans; Hyperuricemia; Inflammasomes; Kidney; Male; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Oxonic Acid; Rats; Rats, Sprague-Dawley; Sirtuin 1; Stilbenes

2017
Total Synthesis of Two Glycosylated Stilbenes, Oxyresveratrol 2-O-β-d-Glucopyranoside and 2,3,5,4'-Tetrahydroxystilbene 2-O-β-d-Glucopyranoside.
    Journal of natural products, 2017, 05-26, Volume: 80, Issue:5

    Topics: Chromatography, High Pressure Liquid; Glucosides; Glycosylation; Humans; Polygonum; Rhizome; Stilbenes

2017
Protective effects of polydatin on experimental testicular torsion and detorsion injury in rats.
    Reproduction, fertility, and development, 2017, Volume: 29, Issue:12

    Topics: Animals; Antioxidants; Apoptosis; Catalase; Glucosides; Glutathione Peroxidase; Male; Malondialdehyde; Orchiectomy; Oxidative Stress; Protective Agents; Rats; Rats, Sprague-Dawley; Spermatic Cord Torsion; Stilbenes; Superoxide Dismutase; Testis

2017
Polydatin down-regulates the phosphorylation level of Creb and induces apoptosis in human breast cancer cell.
    PloS one, 2017, Volume: 12, Issue:5

    Topics: Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cyclic AMP Response Element-Binding Protein; Down-Regulation; Glucosides; Humans; Phosphorylation; S Phase; Stilbenes

2017
HO-1 Is Essential for Tetrahydroxystilbene Glucoside Mediated Mitochondrial Biogenesis and Anti-Inflammation Process in LPS-Treated RAW264.7 Macrophages.
    Oxidative medicine and cellular longevity, 2017, Volume: 2017

    Topics: Animals; Anti-Inflammatory Agents; Glucosides; Heme Oxygenase-1; Interleukin-6; Lipopolysaccharides; Macrophages; Membrane Proteins; Mice; Mitochondria; RAW 264.7 Cells; Stilbenes; Tumor Necrosis Factor-alpha

2017
Polydatin reduces Staphylococcus aureus lipoteichoic acid-induced injury by attenuating reactive oxygen species generation and TLR2-NFκB signalling.
    Journal of cellular and molecular medicine, 2017, Volume: 21, Issue:11

    Topics: Animals; Antioxidants; Cell Survival; Endometriosis; Female; Gene Expression Regulation; Glucosides; I-kappa B Proteins; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Mice; Mice, Inbred BALB C; Oxidative Stress; Protective Agents; RAW 264.7 Cells; Reactive Oxygen Species; Signal Transduction; Staphylococcus aureus; Stilbenes; Teichoic Acids; Toll-Like Receptor 2; Transcription Factor RelA; Uterus

2017
Antidepressant-like effects of tetrahydroxystilbene glucoside in mice: Involvement of BDNF signaling cascade in the hippocampus.
    CNS neuroscience & therapeutics, 2017, Volume: 23, Issue:7

    Topics: Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Chronic Disease; Depressive Disorder; Disease Models, Animal; Dominance-Subordination; Glucosides; Hippocampus; Male; Mice, Inbred C57BL; Motor Activity; Neurogenesis; Receptor, trkB; Serotonin; Signal Transduction; Stilbenes; Stress, Psychological

2017
trans-Polydatin protects the mouse heart against ischemia/reperfusion injury via inhibition of the renin-angiotensin system (RAS) and Rho kinase (ROCK) activity.
    Food & function, 2017, Jun-21, Volume: 8, Issue:6

    Topics: Animals; Apoptosis; Glucosides; Heart; Humans; Ischemia; Male; Mice; Mice, Inbred C57BL; Myocardial Reperfusion Injury; Myocardium; Renin-Angiotensin System; rho-Associated Kinases; Signal Transduction; Stilbenes

2017
Pterostilbene 4'-
    Oxidative medicine and cellular longevity, 2017, Volume: 2017

    Topics: Animals; Colitis; Disease Models, Animal; Glucosides; Male; Mice; Mice, Knockout; Stilbenes; Tristetraprolin

2017
Polydatin alleviated radiation-induced lung injury through activation of Sirt3 and inhibition of epithelial-mesenchymal transition.
    Journal of cellular and molecular medicine, 2017, Volume: 21, Issue:12

    Topics: Acute Lung Injury; Animals; Cell Line; Disease Models, Animal; Epithelial Cells; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation; Glucosides; Humans; Lung; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Radiation Pneumonitis; Radiation-Protective Agents; Signal Transduction; Sirtuin 3; Smad3 Protein; Stilbenes; Th1-Th2 Balance; Transforming Growth Factor beta1

2017
Effects of a co-micronized composite containing palmitoylethanolamide and polydatin in an experimental model of benign prostatic hyperplasia.
    Toxicology and applied pharmacology, 2017, 08-15, Volume: 329

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Amides; Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; Dihydrotestosterone; Dinoprostone; Disease Models, Animal; Drug Combinations; Drug Compounding; Ethanolamines; Glucosides; Inflammation Mediators; Male; Oxidative Stress; Palmitic Acids; Prostate; Prostatic Hyperplasia; Rats, Sprague-Dawley; Signal Transduction; Stilbenes; Testosterone Propionate

2017
Enhanced absorption and inhibited metabolism of emodin by 2, 3, 5, 4'-tetrahydroxystilbene-2-O-β-D-glucopyranoside: Possible mechanisms for Polygoni Multiflori Radix-induced liver injury.
    Chinese journal of natural medicines, 2017, Volume: 15, Issue:6

    Topics: Caco-2 Cells; Chemical and Drug Induced Liver Injury; Emodin; Fallopia multiflora; Glucosides; Glucuronosyltransferase; Humans; Plant Roots; Stilbenes

2017
Cis-stilbene glucoside in Polygonum multiflorum induces immunological idiosyncratic hepatotoxicity in LPS-treated rats by suppressing PPAR-γ.
    Acta pharmacologica Sinica, 2017, Volume: 38, Issue:10

    Topics: Animals; Chemical and Drug Induced Liver Injury; Emodin; Fallopia multiflora; Glucosides; Lipopolysaccharides; Male; Microarray Analysis; NF-kappa B; Pioglitazone; Plant Roots; PPAR gamma; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Stereoisomerism; Stilbenes; Thiazolidinediones

2017
Polydatin protects against carbon tetrachloride-induced liver fibrosis in mice.
    Archives of biochemistry and biophysics, 2017, 09-01, Volume: 629

    Topics: Aldehydes; Animals; Carbon Tetrachloride; Female; Gene Expression Regulation; Glucosides; Liver; Liver Cirrhosis; Male; Mice; Mice, Inbred C57BL; NADPH Oxidase 4; NADPH Oxidases; Oxidative Stress; Stilbenes

2017
Palmitoylethanolamide and Polydatin combination reduces inflammation and oxidative stress in vascular injury.
    Pharmacological research, 2017, Volume: 123

    Topics: Amides; Animals; Anti-Inflammatory Agents; Aorta; Apoptosis; Carotid Arteries; Carotid Artery Injuries; Cytokines; Drug Therapy, Combination; Ethanolamines; Glucosides; Intercellular Adhesion Molecule-1; Mice, Inbred C57BL; NF-KappaB Inhibitor alpha; Nitric Oxide Synthase Type II; Norepinephrine; Oxidative Stress; Palmitic Acids; Stilbenes; Transcription Factor RelA; Vascular Cell Adhesion Molecule-1; Vascular System Injuries

2017
[Polydatin induces human cervical cancer cell apoptosis via PI3K/AKT/mTOR signaling pathway].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2017, Volume: 42, Issue:12

    Topics: Apoptosis; Cell Proliferation; Female; Glucosides; HeLa Cells; Humans; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; Stilbenes; TOR Serine-Threonine Kinases

2017
Tetrahydroxy stilbene glucoside ameliorates H2O2-induced human brain microvascular endothelial cell dysfunction in vitro by inhibiting oxidative stress and inflammatory responses.
    Molecular medicine reports, 2017, Volume: 16, Issue:4

    Topics: Brain; Cell Proliferation; Cell Survival; DNA Damage; Endothelial Cells; Glucosides; Humans; Hydrogen Peroxide; Inflammation; Oxidative Stress; Reactive Oxygen Species; Stilbenes

2017
2,3,4',5-tetrahydroxystilbene-2-O-β-d-glycoside attenuates atherosclerosis in apolipoprotein E-deficient mice: role of reverse cholesterol transport.
    Canadian journal of physiology and pharmacology, 2018, Volume: 96, Issue:1

    Topics: Animals; Apolipoproteins E; Atherosclerosis; Biological Transport; Cholesterol; Fatty Liver; Foam Cells; Glucosides; Hyperlipidemias; Inflammation; Lipid Metabolism; Macrophages; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; RAW 264.7 Cells; Stilbenes

2018
[Chemical constituents from Polygonum multiflorum].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2016, Volume: 41, Issue:17

    Topics: Chromatography, High Pressure Liquid; Fallopia multiflora; Glucosides; Phytochemicals; Plants, Medicinal; Stilbenes

2016
Polydatin inhibits mast cell-mediated allergic inflammation by targeting PI3K/Akt, MAPK, NF-κB and Nrf2/HO-1 pathways.
    Scientific reports, 2017, 09-19, Volume: 7, Issue:1

    Topics: Anaphylaxis; Animals; Cell Degranulation; Cytokines; Dermatitis, Atopic; Extracellular Signal-Regulated MAP Kinases; Glucosides; Heme Oxygenase-1; Inflammation; Male; MAP Kinase Signaling System; Mast Cells; Membrane Proteins; Mice; Mice, Inbred BALB C; NF-E2-Related Factor 2; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Stilbenes

2017
Polydatin ameliorates diabetic cardiomyopathy via Sirt3 activation.
    Biochemical and biophysical research communications, 2017, 11-25, Volume: 493, Issue:3

    Topics: Animals; Autophagosomes; Autophagy; Cardiotonic Agents; Diabetic Cardiomyopathies; Glucosides; Mice, Inbred C57BL; Mice, Knockout; Mitochondria, Heart; Myocytes, Cardiac; Sirtuin 3; Stilbenes; Up-Regulation

2017
Protective effects of the resveratrol analog piceid in dopaminergic SH-SY5Y cells.
    Archives of toxicology, 2018, Volume: 92, Issue:2

    Topics: Apoptosis; Caspase 3; Caspase 7; Cell Line, Tumor; Dopamine; Dopaminergic Neurons; Extracellular Signal-Regulated MAP Kinases; Glucosides; Humans; Neuroprotective Agents; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Resveratrol; Stilbenes

2018
2,3,5,4‑tetrahydroxy diphenylethylene‑2‑O‑glucoside inhibits the adhesion and invasion of A549 human lung cancer cells.
    Molecular medicine reports, 2017, Volume: 16, Issue:6

    Topics: Antineoplastic Agents; Biomarkers; Cell Adhesion; Cell Line, Tumor; Cell Movement; Gene Expression Regulation; Glucosides; Humans; Lung Neoplasms; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Stilbenes

2017
Polydatin Prevents Methylglyoxal-Induced Apoptosis through Reducing Oxidative Stress and Improving Mitochondrial Function in Human Umbilical Vein Endothelial Cells.
    Oxidative medicine and cellular longevity, 2017, Volume: 2017

    Topics: Apoptosis; Drugs, Chinese Herbal; Endothelial Cells; Glucosides; Human Umbilical Vein Endothelial Cells; Humans; Mitochondria; Oxidative Stress; Stilbenes

2017
The natural compound 2,3,5,4'-tetrahydroxystilbene-2-O-β-d glucoside protects against adriamycin-induced nephropathy through activating the Nrf2-Keap1 antioxidant pathway.
    Environmental toxicology, 2018, Volume: 33, Issue:1

    Topics: Albuminuria; Animals; Antioxidants; Cell Line; Doxorubicin; Female; Glucosides; Heme Oxygenase-1; Hypercholesterolemia; Kelch-Like ECH-Associated Protein 1; Kidney; Lipid Peroxidation; Mice; Mice, Inbred BALB C; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Polygonum; RNA Interference; RNA, Small Interfering; Stilbenes

2018
Stilbene Glucoside, a Putative Sleep Promoting Constituent from Polygonum multiflorum Affects Sleep Homeostasis by Affecting the Activities of Lactate Dehydrogenase and Salivary Alpha Amylase.
    Chemical & pharmaceutical bulletin, 2017, Volume: 65, Issue:11

    Topics: Animals; Dose-Response Relationship, Drug; Electrodes; Glucosides; Homeostasis; L-Lactate Dehydrogenase; Mice; Mice, Inbred Strains; Models, Molecular; Molecular Structure; Polygonum; Salivary alpha-Amylases; Sleep; Stilbenes; Structure-Activity Relationship

2017
Tetrahydroxystilbene glucoside modulates amyloid precursor protein processing via activation of AKT-GSK3β pathway in cells and in APP/PS1 transgenic mice.
    Biochemical and biophysical research communications, 2018, 01-01, Volume: 495, Issue:1

    Topics: Amyloid beta-Protein Precursor; Animals; Brain; Dose-Response Relationship, Drug; Enzyme Activation; Glucosides; Glycogen Synthase Kinase 3 beta; HEK293 Cells; Humans; Metabolic Networks and Pathways; Mice; Mice, Transgenic; Oncogene Protein v-akt; Stilbenes

2018
In vivo assessment of polydatin, a natural polyphenol compound, on arsenic-induced free radical overproduction, gene expression, and genotoxicity.
    Environmental science and pollution research international, 2018, Volume: 25, Issue:3

    Topics: Animals; Antioxidants; Arsenic; DNA Damage; Drugs, Chinese Herbal; Erythrocytes; Free Radicals; Gene Expression; Glucosides; Male; Oxidative Stress; Rats, Wistar; Stilbenes; Water Pollutants, Chemical

2018
Stable isotope labeling and 2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucopyranoside biosynthetic pathway characterization in Fallopia multiflora.
    Planta, 2018, Volume: 247, Issue:3

    Topics: Fallopia multiflora; Glucosides; Glycosylation; Hydroxylation; Isotope Labeling; Metabolic Networks and Pathways; Resveratrol; Stilbenes

2018
    mBio, 2017, 11-21, Volume: 8, Issue:6

    Topics: Biological Availability; Dietary Carbohydrates; Gastrointestinal Microbiome; Glucosides; Humans; Hydrolysis; Lactobacillus acidophilus; Phytochemicals; Polyphenols; Resveratrol; Stilbenes

2017
2,3,5,4'‑Tetrahydroxystilbene‑2‑O‑β‑D‑glucoside inhibits septic serum‑induced inflammatory injury via interfering with the ROS‑MAPK‑NF‑κB signaling pathway in pulmonary aortic endothelial cells.
    International journal of molecular medicine, 2018, Volume: 41, Issue:3

    Topics: Animals; Aorta; Cell Survival; Cells, Cultured; Cytokines; Endothelial Cells; Glucosides; Inflammation; Lung; Male; Mitogen-Activated Protein Kinases; NF-kappa B; Phosphorylation; Rats, Sprague-Dawley; Reactive Oxygen Species; RNA, Messenger; Sepsis; Signal Transduction; Stilbenes; Superoxides

2018
Multiflorumisides A-G, Dimeric Stilbene Glucosides with Rare Coupling Patterns from the Roots of Polygonum multiflorum.
    Journal of natural products, 2018, 02-23, Volume: 81, Issue:2

    Topics: Animals; Fallopia multiflora; Glucosides; Mice; Nitric Oxide; Plant Roots; RAW 264.7 Cells; Stilbenes

2018
Polydatin inhibits the IL-1β-induced inflammatory response in human osteoarthritic chondrocytes by activating the Nrf2 signaling pathway and ameliorates murine osteoarthritis.
    Food & function, 2018, Mar-01, Volume: 9, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Chondrocytes; Glucosides; Humans; Interleukin-1beta; Interleukin-6; Male; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Osteoarthritis; Signal Transduction; Stilbenes

2018
In Vitro and In Vivo Anti-Osteoarthritis Effects of 2,3,5,4'-Tetrahydroxystilbene-2-O-β-d-Glucoside from Polygonum Multiflorum.
    Molecules (Basel, Switzerland), 2018, Mar-03, Volume: 23, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Chondrocytes; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Edema; Gene Expression Regulation; Glucosides; Hindlimb; Iodoacetic Acid; Lipopolysaccharides; Male; Matrix Metalloproteinase 13; Mice; Nitric Oxide; Nitric Oxide Synthase Type II; Osteoarthritis; Polygonum; Primary Cell Culture; Rats; RAW 264.7 Cells; Stilbenes

2018
Polydatin inhibits cell proliferation, invasion and migration, and induces cell apoptosis in hepatocellular carcinoma.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2018, Mar-01, Volume: 51, Issue:4

    Topics: Animals; Apoptosis; Blotting, Western; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drugs, Chinese Herbal; Flow Cytometry; Glucosides; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Real-Time Polymerase Chain Reaction; Stilbenes

2018
A surface magnetic imprinted polymers as artificial receptors for selective and efficient capturing of new neuronal nitric oxide synthase-post synaptic density protein-95 uncouplers.
    Journal of pharmaceutical and biomedical analysis, 2018, May-30, Volume: 154

    Topics: Animals; Cell Line, Tumor; Disks Large Homolog 4 Protein; Emodin; Glucosides; Magnetics; Molecular Imprinting; Neuroprotective Agents; Nitric Oxide Synthase Type I; PC12 Cells; Polymers; Post-Synaptic Density; Rats; Receptors, Artificial; Solid Phase Extraction; Solvents; Stilbenes

2018
Switching glycosyltransferase UGT
    Organic & biomolecular chemistry, 2018, 04-04, Volume: 16, Issue:14

    Topics: Bacillus licheniformis; Bacterial Proteins; Glucosides; Glucosyltransferases; Glycosylation; Kinetics; Mutation; Protein Engineering; Resveratrol; Stilbenes

2018
Tetrahydroxystilbene Glucoside Produces Neuroprotection against 6-OHDA-Induced Dopamine Neurotoxicity.
    Oxidative medicine and cellular longevity, 2018, Volume: 2018

    Topics: Animals; Dopamine; Glucosides; Male; Neuroprotective Agents; Neurotoxicity Syndromes; Oxidopamine; Parkinson Disease, Secondary; Random Allocation; Rats; Stilbenes

2018
UHPLC/MS Identifying Potent α-glucosidase Inhibitors of Grape Pomace via Enzyme Immobilized Method.
    Journal of food science, 2018, Volume: 83, Issue:4

    Topics: Acetates; alpha-Glucosidases; Benzofurans; Catechin; Chitosan; Chromatography, High Pressure Liquid; Coumarins; Enzymes, Immobilized; Glucosides; Glycoside Hydrolase Inhibitors; Hypoglycemic Agents; Mass Spectrometry; Plant Extracts; Polymers; Stilbenes; Vitis

2018
2,3,5,4'-Tetrahydroxystilbene-2-O-β-glucoside potentiates self-renewal of human dental pulp stem cells via the AMPK/ERK/SIRT1 axis.
    International endodontic journal, 2018, Volume: 51, Issue:10

    Topics: Blotting, Western; Cell Proliferation; Cell Survival; Dental Pulp; Extracellular Signal-Regulated MAP Kinases; Gene Expression; Glucosides; Humans; MAP Kinase Signaling System; Real-Time Polymerase Chain Reaction; RNA, Messenger; Sirtuin 1; Stem Cells; Stilbenes

2018
Contribution to the study of rutin stability in the achenes of Tartary buckwheat (Fagopyrum tataricum).
    Food chemistry, 2018, Aug-30, Volume: 258

    Topics: Chemical Fractionation; Chromatography, High Pressure Liquid; Fagopyrum; Flavonoids; Freeze Drying; Glucosides; Glycosylation; Kaempferols; Quercetin; Rutin; Seeds; Stilbenes

2018
Tetrahydroxystilbene glycoside antagonizes β-amyloid-induced inflammatory injury in microglia cells by regulating PU.1 expression.
    Neuroreport, 2018, 07-04, Volume: 29, Issue:10

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Arginase; Brain-Derived Neurotrophic Factor; Cells, Cultured; Glucosides; Inflammation; Interleukin-1beta; Mice; Microglia; NF-kappa B; Nitric Oxide Synthase Type II; Stilbenes; Tumor Necrosis Factor-alpha

2018
A new inhibitor of glucose-6-phosphate dehydrogenase blocks pentose phosphate pathway and suppresses malignant proliferation and metastasis in vivo.
    Cell death & disease, 2018, 05-01, Volume: 9, Issue:5

    Topics: Animals; Glucosephosphate Dehydrogenase; Glucosides; Humans; Male; MCF-7 Cells; Mice, Nude; Neoplasm Metastasis; Neoplasm Proteins; Neoplasms; Pentose Phosphate Pathway; S Phase Cell Cycle Checkpoints; Stilbenes; Xenograft Model Antitumor Assays

2018
[Polydatin inhibits cell proliferation and expressions of inflammatory cytokines in THP-1 cells induced by ox-LDL via up-regulating SIRT1].
    Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, 2018, Volume: 34, Issue:3

    Topics: Cell Proliferation; Chemokine CCL2; Cytokines; Glucosides; Humans; Interleukin-6; Lipoproteins, LDL; Macrophages; Malondialdehyde; Oxidative Stress; Reactive Oxygen Species; Sirtuin 1; Stilbenes; Superoxide Dismutase; THP-1 Cells; Tumor Necrosis Factor-alpha; Up-Regulation

2018
In Vitro Estrogenic and Breast Cancer Inhibitory Activities of Chemical Constituents Isolated from Rheum undulatum L.
    Molecules (Basel, Switzerland), 2018, May-18, Volume: 23, Issue:5

    Topics: Anthraquinones; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Synergism; Emodin; Estrogen Receptor alpha; Estrogens; Female; Fulvestrant; Glucosides; Humans; Molecular Structure; Plant Extracts; Plant Roots; Rheum; Stilbenes; Structure-Activity Relationship

2018
Escherichia coli modular coculture system for resveratrol glucosides production.
    World journal of microbiology & biotechnology, 2018, May-23, Volume: 34, Issue:6

    Topics: Batch Cell Culture Techniques; Bioreactors; Biosynthetic Pathways; Biotransformation; Coculture Techniques; Coumaric Acids; DNA, Bacterial; Escherichia coli; Fermentation; Genetic Vectors; Glucosides; Glucosyltransferases; Metabolic Engineering; Resveratrol; Stilbenes; Temperature

2018
Dual modulation on glial cells by tetrahydroxystilbene glucoside protects against dopamine neuronal loss.
    Journal of neuroinflammation, 2018, May-25, Volume: 15, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Cells, Cultured; Coculture Techniques; Dopamine; Dopaminergic Neurons; Embryo, Mammalian; Gene Expression Regulation; Glucosides; Lipopolysaccharides; Male; Neuroglia; Neuroprotective Agents; Neurotransmitter Agents; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Stilbenes; Substantia Nigra; Tritium; Tyrosine 3-Monooxygenase

2018
Tetrahydroxystilbene Glucoside Delayed Senile Symptoms in Old Mice via Regulation of the AMPK/SIRT1/PGC-1α Signaling Cascade.
    Gerontology, 2018, Volume: 64, Issue:5

    Topics: Aging; AMP-Activated Protein Kinases; Animals; Bone Density; Cell Line; Drugs, Chinese Herbal; Energy Intake; Female; Glucosides; HeLa Cells; Humans; Mice; Mice, Inbred C57BL; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Signal Transduction; Sirtuin 1; Stilbenes

2018
Polydatin Improves Glucose and Lipid Metabolisms in Insulin-Resistant HepG2 Cells through the AMPK Pathway.
    Biological & pharmaceutical bulletin, 2018, Volume: 41, Issue:6

    Topics: Acetyl-CoA Carboxylase; AMP-Activated Protein Kinases; Glucose; Glucosides; Glycogen Synthase Kinase 3 beta; Hep G2 Cells; Humans; Insulin Resistance; Lipid Metabolism; Proto-Oncogene Proteins c-akt; Receptors, LDL; Signal Transduction; Sterol Regulatory Element Binding Protein 1; Stilbenes

2018
Tetrahydroxy Stilbene Glucoside Alleviates High Glucose-Induced MPC5 Podocytes Injury Through Suppression of NLRP3 Inflammasome.
    The American journal of the medical sciences, 2018, Volume: 355, Issue:6

    Topics: Animals; Antioxidants; Apoptosis; Caspase 3; Cell Survival; Glucose; Glucosides; Inflammasomes; Mice; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Podocytes; Reactive Oxygen Species; Signal Transduction; Stilbenes

2018
Novel Anti-arthritic Mechanisms of Polydatin in Complete Freund's Adjuvant-Induced Arthritis in Rats: Involvement of IL-6, STAT-3, IL-17, and NF-кB.
    Inflammation, 2018, Volume: 41, Issue:5

    Topics: Animals; Arthritis, Experimental; Freund's Adjuvant; Gene Expression Regulation; Glucosides; Interleukin-17; Interleukin-6; NF-kappa B; Rats; STAT3 Transcription Factor; Stilbenes

2018
Polydatin suppresses VEGF-induced angiogenesis through binding with VEGF and inhibiting its receptor signaling.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019, Volume: 33, Issue:1

    Topics: Angiogenesis Inhibitors; Animals; Cell Movement; Cell Proliferation; Glucosides; Human Umbilical Vein Endothelial Cells; Humans; Neovascularization, Physiologic; Phosphorylation; Signal Transduction; Stilbenes; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2; Zebrafish

2019
Polydatin, Natural Precursor of Resveratrol, Promotes Osteogenic Differentiation of Mesenchymal Stem Cells.
    International journal of medical sciences, 2018, Volume: 15, Issue:9

    Topics: Cell Differentiation; Cells, Cultured; Child; Glucosides; Humans; Male; Mesenchymal Stem Cells; Osteogenesis; Resveratrol; Stilbenes

2018
Polydatin prevents fructose-induced liver inflammation and lipid deposition through increasing miR-200a to regulate Keap1/Nrf2 pathway.
    Redox biology, 2018, Volume: 18

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Cell Line; Drugs, Chinese Herbal; Fructose; Glucosides; Inflammation; Kelch-Like ECH-Associated Protein 1; Lipids; Liver; Male; MicroRNAs; NF-E2-Related Factor 2; Oxidative Stress; Rats, Sprague-Dawley; Signal Transduction; Stilbenes

2018
Aryl hydrocarbon receptor, a tumor grade‑associated marker of oral cancer, is directly downregulated by polydatin: A pilot study.
    Oncology reports, 2018, Volume: 40, Issue:3

    Topics: Apoptosis; Basic Helix-Loop-Helix Transcription Factors; Biomarkers, Tumor; Carcinoma, Squamous Cell; Case-Control Studies; Cell Proliferation; Cytochrome P-450 CYP1A1; Female; Follow-Up Studies; Gene Expression Regulation, Neoplastic; Glucosides; HSP90 Heat-Shock Proteins; Humans; Male; Middle Aged; Mouth Neoplasms; Neoplasm Grading; Pilot Projects; Receptors, Aryl Hydrocarbon; Stilbenes; Tumor Cells, Cultured

2018
Production of Bioactive 3'-Hydroxystilbene Compounds Using the Flavin-Dependent Monooxygenase Sam5.
    Journal of microbiology and biotechnology, 2018, Jul-28, Volume: 28, Issue:7

    Topics: Dinitrocresols; Escherichia coli; Flavins; Glucosides; Hydroxylation; Mixed Function Oxygenases; Plant Extracts; Resveratrol; Stilbenes

2018
Quantification of eight active ingredients in crude and processed radix polygoni multiflori applying miniaturized matrix solid-phase dispersion microextraction followed by UHPLC.
    Journal of separation science, 2018, Volume: 41, Issue:17

    Topics: Catechin; Chromatography, High Pressure Liquid; Emodin; Fallopia multiflora; Gallic Acid; Glucosides; Particle Size; Solid Phase Microextraction; Stilbenes; Surface Properties

2018
The influence of polysaccharides from Ophiopogon japonicus on 2,3,5,4'-tetrahydroxy-stilbene-2-O-β-d-glucoside about biopharmaceutical properties in vitro and pharmacokinetics in vivo.
    International journal of biological macromolecules, 2018, Volume: 119

    Topics: Drug Interactions; Glucosides; Ophiopogon; Permeability; Polysaccharides; Solubility; Stilbenes

2018
Polydatin attenuates reactive oxygen species-induced airway remodeling by promoting Nrf2-mediated antioxidant signaling in asthma mouse model.
    Life sciences, 2019, Feb-01, Volume: 218

    Topics: Airway Remodeling; Animals; Antioxidants; Asthma; Cells, Cultured; Disease Models, Animal; Epithelial Cells; Epithelial-Mesenchymal Transition; Glucosides; Humans; Lung; Male; Mice; Mice, Inbred BALB C; Mice, Nude; NF-E2-Related Factor 2; Ovalbumin; Reactive Oxygen Species; Signal Transduction; Stilbenes; Transforming Growth Factor beta1

2019
Protective effects of 2,3,5,4-tetrahydroxystilbene-2-o-β-D-glucoside against osteoporosis: Current knowledge and proposed mechanisms.
    International journal of rheumatic diseases, 2018, Volume: 21, Issue:8

    Topics: 3T3 Cells; Animals; Apoptosis; Bone Density Conservation Agents; Bone Remodeling; Chemokines; Disease Models, Animal; Female; Forkhead Box Protein O3; Glucosides; Humans; Mice; Mice, Inbred BALB C; Osteoblasts; Osteoporosis, Postmenopausal; Ovariectomy; Oxidative Stress; Stilbenes; TCF Transcription Factors; Wnt Signaling Pathway

2018
Protective Effects of 2,3,5,4'-Tetrahydroxystilbene-2-
    International journal of molecular sciences, 2018, Aug-28, Volume: 19, Issue:9

    Topics: Animals; Biomarkers; Body Weight; Bone and Bones; Disease Models, Animal; Glucosides; Humans; Mice; Organ Size; Osteoporosis; Ovariectomy; Plant Extracts; Protective Agents; Stilbenes; X-Ray Microtomography

2018
Polydatin protects against acute myocardial infarction-induced cardiac damage by activation of Nrf2/HO-1 signaling.
    Journal of natural medicines, 2019, Volume: 73, Issue:1

    Topics: Acute Disease; Animals; Apoptosis; Drugs, Chinese Herbal; Glucosides; Humans; Male; Myocardial Infarction; Myocytes, Cardiac; NF-E2-Related Factor 2; Protective Agents; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Stilbenes

2019
Tetrahydroxystilbene Glucoside Regulates Proliferation, Differentiation, and OPG/RANKL/M-CSF Expression in MC3T3-E1 Cells via the PI3K/Akt Pathway.
    Molecules (Basel, Switzerland), 2018, Sep-10, Volume: 23, Issue:9

    Topics: Animals; Cell Cycle; Cell Differentiation; Cell Line; Cell Proliferation; Cell Survival; Chromones; DNA; Down-Regulation; Glucosides; Macrophage Colony-Stimulating Factor; Mice; Morpholines; Osteoprotegerin; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; RANK Ligand; RNA, Messenger; Signal Transduction; Stilbenes; Up-Regulation

2018
Polydatin suppresses proliferation and metastasis of non-small cell lung cancer cells by inhibiting NLRP3 inflammasome activation via NF-κB pathway.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 108

    Topics: Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Cell Proliferation; Glucosides; Humans; Inflammasomes; Neoplasm Metastasis; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Signal Transduction; Stilbenes

2018
Polydatin ameliorates dextran sulfate sodium-induced colitis by decreasing oxidative stress and apoptosis partially via Sonic hedgehog signaling pathway.
    International immunopharmacology, 2018, Volume: 64

    Topics: Animals; Apoptosis; Colitis; Dextran Sulfate; Glucosides; Hedgehog Proteins; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Signal Transduction; Stilbenes

2018
A New Strategy for Rapidly Screening Natural Inhibitors Targeting the PCSK9/LDLR Interaction In Vitro.
    Molecules (Basel, Switzerland), 2018, Sep-19, Volume: 23, Issue:9

    Topics: Biological Products; Cell Line, Tumor; Drugs, Chinese Herbal; Glucosides; Hep G2 Cells; Humans; Hypercholesterolemia; PCSK9 Inhibitors; Proprotein Convertase 9; Protein Binding; Receptors, LDL; Stilbenes

2018
Polydatin alleviated alcoholic liver injury in zebrafish larvae through ameliorating lipid metabolism and oxidative stress.
    Journal of pharmacological sciences, 2018, Volume: 138, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Aryl Hydrocarbon Hydroxylases; Cell Cycle Proteins; Cytochrome P450 Family 3; DNA Damage; Fallopia japonica; Gene Expression; Glucosides; Lipid Metabolism; Liver Diseases, Alcoholic; Nuclear Proteins; Oxidative Stress; Oxidoreductases, N-Demethylating; Phytotherapy; Stilbenes; Zebrafish; Zebrafish Proteins

2018
Protective effect of polydatin on radiation-induced injury of intestinal epithelial and endothelial cells.
    Bioscience reports, 2018, 12-21, Volume: 38, Issue:6

    Topics: Animals; Apoptosis; Endothelial Cells; Glucosides; Humans; Ileum; Intestinal Mucosa; Mice; Radiation Injuries, Experimental; Radiation-Protective Agents; Stilbenes

2018
Polydatin Regulates the Apoptosis and Autophagy of Fibroblasts Obtained from Patients with Ankylosing Spondylitis.
    Biological & pharmaceutical bulletin, 2019, Jan-01, Volume: 42, Issue:1

    Topics: Adult; Apoptosis; Autophagy; Cells, Cultured; Female; Fibroblasts; Glucosides; Humans; Male; Middle Aged; Spondylitis, Ankylosing; Stilbenes

2019
Polydatin suppresses nucleus pulposus cell senescence, promotes matrix homeostasis and attenuates intervertebral disc degeneration in rats.
    Journal of cellular and molecular medicine, 2018, Volume: 22, Issue:11

    Topics: ADAMTS4 Protein; Aggrecans; Animals; Cells, Cultured; Cellular Senescence; Collagen; Disease Models, Animal; Extracellular Matrix; Glucosides; Humans; Intervertebral Disc; Intervertebral Disc Degeneration; Low Back Pain; Matrix Metalloproteinase 13; Matrix Metalloproteinase 3; NF-E2-Related Factor 2; Nucleus Pulposus; Rats; Stilbenes; Tumor Necrosis Factor-alpha

2018
Tetrahydroxystilbene glucoside-induced relaxation of the superior mesenteric artery via both endothelium-dependent and endothelium-independent mechanisms.
    Microvascular research, 2019, Volume: 123

    Topics: Animals; Calcium Signaling; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Endothelium, Vascular; Glucosides; Male; Mesenteric Artery, Superior; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Potassium Channels, Voltage-Gated; Rats, Sprague-Dawley; Stilbenes; Thromboxane A2; Vasodilation; Vasodilator Agents

2019
Polydatin protects against acetaminophen-induced hepatotoxicity in mice via anti-oxidative and anti-apoptotic activities.
    Food & function, 2018, Nov-14, Volume: 9, Issue:11

    Topics: Acetaminophen; Alanine Transaminase; Animals; Antioxidants; Apoptosis; Apoptotic Protease-Activating Factor 1; Aspartate Aminotransferases; bcl-2-Associated X Protein; Caspase 3; Caspase 9; Chemical and Drug Induced Liver Injury; Glucosides; Glutathione; Glutathione Disulfide; Glutathione Peroxidase; Hepatocytes; Liver; Male; Malondialdehyde; Mice; Mice, Inbred ICR; NADPH Oxidase 2; Nitric Oxide Synthase Type II; Oxidative Stress; Protective Agents; Reactive Oxygen Species; Stilbenes

2018
Polydatin effectively attenuates disease activity in lupus-prone mouse models by blocking ROS-mediated NET formation.
    Arthritis research & therapy, 2018, Nov-12, Volume: 20, Issue:1

    Topics: Animals; Cells, Cultured; Disease Models, Animal; Disease Progression; Drugs, Chinese Herbal; Extracellular Traps; Female; Glucosides; Humans; Lupus Erythematosus, Systemic; Mice; Mice, Inbred BALB C; Reactive Oxygen Species; Stilbenes; Treatment Outcome

2018
Pterostilbene 4'-
    Oxidative medicine and cellular longevity, 2018, Volume: 2018

    Topics: Acute Lung Injury; Animals; Antioxidants; Disease Models, Animal; Enzyme Induction; Epithelial Cells; Glucosides; Heme Oxygenase-1; Humans; Inflammation; Lipopolysaccharides; Lung; Macrophages; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Pseudomonas aeruginosa; RAW 264.7 Cells; RNA, Messenger; Stilbenes; Up-Regulation

2018
Polydatin Prevents Lipopolysaccharide (LPS)-Induced Parkinson's Disease via Regulation of the AKT/GSK3β-Nrf2/NF-κB Signaling Axis.
    Frontiers in immunology, 2018, Volume: 9

    Topics: Animals; Cell Line; Cytokines; Dopaminergic Neurons; Glucosides; Glycogen Synthase Kinase 3 beta; Lipopolysaccharides; Mice; Microglia; Neuroprotective Agents; NF-E2-Related Factor 2; NF-kappa B; Parkinson Disease; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Stilbenes; Substantia Nigra

2018
Tetrahydroxy stilbene glucoside protected against diabetes-induced osteoporosis in mice with streptozotocin-induced hyperglycemia.
    Phytotherapy research : PTR, 2019, Volume: 33, Issue:2

    Topics: Animals; Bone and Bones; Diabetes Mellitus, Experimental; Femur; Glucosides; Hyperglycemia; Male; Mice; Mice, Inbred C57BL; Osteoblasts; Osteoclasts; Osteogenesis; Osteoporosis; Renin-Angiotensin System; Stilbenes; Streptozocin; Tartrate-Resistant Acid Phosphatase

2019
[Polydatin ameliorates myocardial fibrosis in rats by up-regulating SIRT3 and SDF-1].
    Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, 2018, Volume: 34, Issue:9

    Topics: Animals; Chemokine CXCL12; Fibrosis; Glucosides; Heart Diseases; Male; Rats; Rats, Sprague-Dawley; Sirtuin 1; Sirtuin 3; Stilbenes; Superoxide Dismutase

2018
Pharmacokinetic studies unveiled the drug-drug interaction between trans-2,3,5,4'-tetrahydroxystilbene-2-O-β-d-glucopyranoside and emodin that may contribute to the idiosyncratic hepatotoxicity of Polygoni Multiflori Radix.
    Journal of pharmaceutical and biomedical analysis, 2019, Feb-05, Volume: 164

    Topics: Administration, Oral; Animals; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2; Disease Models, Animal; Drug Interactions; Drugs, Chinese Herbal; Emodin; Glucosides; Humans; Male; Plant Roots; Polygonum; Rats; Rats, Sprague-Dawley; Stilbenes; Tandem Mass Spectrometry

2019
Polydatin attenuates spinal cord injury in rats by inhibiting oxidative stress and microglia apoptosis via Nrf2/HO-1 pathway.
    Life sciences, 2019, Jan-15, Volume: 217

    Topics: Animals; Antioxidants; Apoptosis; Glucosides; Heme Oxygenase-1; Male; Microglia; Neuroprotective Agents; NF-E2-Related Factor 2; Oxidative Stress; Rats; Rats, Sprague-Dawley; Signal Transduction; Spinal Cord Injuries; Stilbenes

2019
Polydatin Attenuates Atherosclerosis in ApoE
    The American journal of Chinese medicine, 2018, Volume: 46, Issue:8

    Topics: Animals; Atherosclerosis; Cholesterol; Cytokines; Down-Regulation; Drugs, Chinese Herbal; Glucosides; Macrophages; Mice; Mice, Knockout; Nicotinamide Phosphoribosyltransferase; Phytotherapy; RAW 264.7 Cells; RNA, Small Interfering; Stilbenes

2018
Polydatin Alleviates Radiation-Induced Testes Injury by Scavenging ROS and Inhibiting Apoptosis Pathways.
    Medical science monitor : international medical journal of experimental and clinical research, 2018, Dec-12, Volume: 24

    Topics: Animals; Antioxidants; Apoptosis; Cell Line; Glucosides; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Radiation Injuries, Experimental; Radiation-Protective Agents; Reactive Oxygen Species; Stilbenes; Testis

2018
The Protective Effects of 2,3,5,4'-Tetrahydroxystilbene-2-
    International journal of molecular sciences, 2018, Dec-12, Volume: 19, Issue:12

    Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Cell Count; Cytokines; Disease Models, Animal; Female; Glucosides; Immunoglobulin Class Switching; Inflammation; Inflammation Mediators; Lung; Mice, Inbred C57BL; Ovalbumin; Protective Agents; Respiratory Hypersensitivity; Stilbenes; Th1 Cells; Th2 Cells

2018
Polydatin suppresses the development of lung inflammation and fibrosis by inhibiting activation of the NACHT domain-, leucine-rich repeat-, and pyd-containing protein 3 inflammasome and the nuclear factor-κB pathway after Mycoplasma pneumoniae infection.
    Journal of cellular biochemistry, 2019, Volume: 120, Issue:6

    Topics: Animals; Cell Line; Drugs, Chinese Herbal; Epithelial Cells; Glucosides; Humans; Inflammasomes; Lung; Mice, Inbred BALB C; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Pneumonia; Pneumonia, Mycoplasma; Protective Agents; Pulmonary Fibrosis; Signal Transduction; Stilbenes

2019
Pterostilbene and Its Glucoside Induce Type XVII Collagen Expression.
    Natural product communications, 2017, Volume: 12, Issue:1

    Topics: Cells, Cultured; Chromatography, High Pressure Liquid; Collagen Type XII; Glucosides; Hair Follicle; Humans; Phytolacca americana; Skin; Stilbenes

2017
The synergistic effect of 2,3,5,4'-Tetrahydroxystilbene-2-O-β-d-glucoside combined with Adriamycin on MCF-7 breast cancer cells.
    Drug design, development and therapy, 2018, Volume: 12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulatory Proteins; Breast Neoplasms; Cell Survival; Dose-Response Relationship, Drug; Doxorubicin; Drug Synergism; Female; Glucosides; Humans; MCF-7 Cells; Phosphatidylinositol 3-Kinase; Proto-Oncogene Proteins c-akt; Signal Transduction; Stilbenes; Vascular Endothelial Growth Factor A

2018
Involvement of stromal cell-derived factor-1α (SDF-1α), stem cell factor (SCF), fractalkine (FKN) and VEGF in TSG protection against intimal hyperplasia in rat balloon injury.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, Volume: 110

    Topics: Angioplasty, Balloon; Animals; Carotid Artery Injuries; Carotid Artery, Common; Chemokine CX3CL1; Chemokine CXCL12; Glucosides; Hyperplasia; Male; Neointima; Random Allocation; Rats; Rats, Sprague-Dawley; Stem Cell Factor; Stilbenes; Vascular Endothelial Growth Factor A

2019
Inhibition of resveratrol glucosides (REs) on advanced glycation endproducts (AGEs) formation: inhibitory mechanism and structure-activity relationship.
    Natural product research, 2020, Volume: 34, Issue:17

    Topics: Antioxidants; Glucosides; Glycation End Products, Advanced; Plant Extracts; Pyruvaldehyde; Resveratrol; Stilbenes; Structure-Activity Relationship

2020
MALAT1 Up-Regulator Polydatin Protects Brain Microvascular Integrity and Ameliorates Stroke Through C/EBPβ/MALAT1/CREB/PGC-1α/PPARγ Pathway.
    Cellular and molecular neurobiology, 2019, Volume: 39, Issue:2

    Topics: Animals; Base Sequence; Blood-Brain Barrier; Brain; CCAAT-Enhancer-Binding Protein-beta; Cyclic AMP Response Element-Binding Protein; Glucosides; HEK293 Cells; Human Umbilical Vein Endothelial Cells; Humans; Infarction, Middle Cerebral Artery; Microvessels; Models, Biological; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; PPAR gamma; Rats, Sprague-Dawley; RNA, Long Noncoding; Stilbenes; Stroke; Time Factors

2019
Piceatannol-3-O-β-D-glucopyranoside (PG) exhibits in vitro anti-metastatic and anti-angiogenic activities in HT1080 malignant fibrosarcoma cells.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2019, Volume: 57

    Topics: Adult; Angiogenesis Inhibitors; Animals; Cell Line, Tumor; Cell Movement; Chick Embryo; Chorioallantoic Membrane; Fibrosarcoma; Glucosides; Human Umbilical Vein Endothelial Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Matrix Metalloproteinase 9; Neovascularization, Pathologic; Stilbenes; Tetradecanoylphorbol Acetate; Vascular Endothelial Growth Factor A

2019
Protective effects of polydatin against sulfur mustard-induced hepatic injury.
    Toxicology and applied pharmacology, 2019, 03-15, Volume: 367

    Topics: Animals; Antioxidants; Cell Line; Chemical and Drug Induced Liver Injury; Chemical Warfare Agents; Glucosides; Hepatocytes; Humans; Liver; Male; Mice, Inbred ICR; Mustard Gas; NF-E2-Related Factor 2; Oxidative Stress; Signal Transduction; Sirtuin 1; Stilbenes

2019
Polydatin Increases Radiosensitivity by Inducing Apoptosis of Stem Cells in Colorectal Cancer.
    International journal of biological sciences, 2019, Volume: 15, Issue:2

    Topics: Animals; Apoptosis; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Glucosides; HCT116 Cells; Humans; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Stilbenes

2019
Polydatin alleviates traumatic spinal cord injury by reducing microglial inflammation via regulation of iNOS and NLRP3 inflammasome pathway.
    International immunopharmacology, 2019, Volume: 70

    Topics: Animals; Behavior, Animal; Cell Line; Drugs, Chinese Herbal; Glucosides; Humans; Inflammasomes; Inflammation Mediators; Male; Microglia; Neuroprotection; Nitric Oxide; Nitric Oxide Synthase Type II; NLR Family, Pyrin Domain-Containing 3 Protein; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries; Stilbenes; Wounds and Injuries

2019
Resveratroloside Alleviates Postprandial Hyperglycemia in Diabetic Mice by Competitively Inhibiting α-Glucosidase.
    Journal of agricultural and food chemistry, 2019, Mar-13, Volume: 67, Issue:10

    Topics: alpha-Glucosidases; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Glucosides; Glycoside Hydrolase Inhibitors; Humans; Hyperglycemia; Male; Mice; Molecular Docking Simulation; Stilbenes

2019
Polydatin mediates Parkin-dependent mitophagy and protects against mitochondria-dependent apoptosis in acute respiratory distress syndrome.
    Laboratory investigation; a journal of technical methods and pathology, 2019, Volume: 99, Issue:6

    Topics: Animals; Apoptosis; Drug Evaluation, Preclinical; Drugs, Chinese Herbal; Fallopia japonica; Glucosides; Male; Mice, Inbred C57BL; Mitophagy; Phytotherapy; Respiratory Distress Syndrome; Stilbenes; Ubiquitin-Protein Ligases

2019
Tetrahydroxy stilbene glucoside alleviates palmitic acid-induced inflammation and apoptosis in cardiomyocytes by regulating miR-129-3p/Smad3 signaling.
    Cellular & molecular biology letters, 2019, Volume: 24

    Topics: Animals; Apoptosis; Cell Line; Glucosides; Inflammation; MicroRNAs; Myocytes, Cardiac; Palmitic Acid; Protective Agents; Rats; Signal Transduction; Smad3 Protein; Stilbenes

2019
Dental Pulp Stem Cell Transplantation with 2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-glucoside Accelerates Alveolar Bone Regeneration in Rats.
    Journal of endodontics, 2019, Volume: 45, Issue:4

    Topics: Adolescent; Adult; Alveolar Bone Loss; Alveolar Process; Animals; Bone Regeneration; Cell Differentiation; Dental Pulp; Disease Models, Animal; Female; Glucosides; Humans; Male; Osteogenesis; Rats, Sprague-Dawley; Regenerative Medicine; Stem Cell Transplantation; Stem Cells; Stilbenes; Stimulation, Chemical; Young Adult

2019
Pharmacokinetics, tissue distribution and excretion study of trans-resveratrol-3-O-glucoside and its two metabolites in rats.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2019, Volume: 58

    Topics: Administration, Oral; Animals; Bile; Biological Availability; Feces; Female; Glucosides; Glucuronides; Male; Rats, Wistar; Stilbenes; Tissue Distribution

2019
Targeting the ROS/PI3K/AKT/HIF-1α/HK2 axis of breast cancer cells: Combined administration of Polydatin and 2-Deoxy-d-glucose.
    Journal of cellular and molecular medicine, 2019, Volume: 23, Issue:5

    Topics: Animals; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Deoxyglucose; Enzymes; Female; Glucosides; Glycolysis; Hexokinase; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; MCF-7 Cells; Mice, Inbred BALB C; Molecular Structure; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Signal Transduction; Stilbenes; Xenograft Model Antitumor Assays

2019
2, 3, 4', 5-tetrahydroxystilbene-2-0-β-d Glycoside Attenuates Age- and Diet-Associated Non-Alcoholic Steatohepatitis and Atherosclerosis in LDL Receptor Knockout Mice and Its Possible Mechanisms.
    International journal of molecular sciences, 2019, Apr-01, Volume: 20, Issue:7

    Topics: Aging; Animals; Aorta; Atherosclerosis; Diet, High-Fat; Glucosides; Lipid Metabolism; Liver; Male; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Receptors, LDL; Stilbenes

2019
Polydatin promotes the osteogenic differentiation of human bone mesenchymal stem cells by activating the BMP2-Wnt/β-catenin signaling pathway.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, Volume: 112

    Topics: beta Catenin; Bone and Bones; Bone Morphogenetic Protein 2; Cell Culture Techniques; Cell Differentiation; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Glucosides; Humans; Mesenchymal Stem Cells; Osteogenesis; Stilbenes; Wnt Signaling Pathway

2019
The phytochemical polydatin ameliorates non-alcoholic steatohepatitis by restoring lysosomal function and autophagic flux.
    Journal of cellular and molecular medicine, 2019, Volume: 23, Issue:6

    Topics: Animals; Autophagy; Disease Models, Animal; Glucosides; Humans; Lysosomes; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Protective Agents; Signal Transduction; Stilbenes

2019
Polydatin inhibits proliferation and promotes apoptosis of doxorubicin-resistant osteosarcoma through LncRNA TUG1 mediated suppression of Akt signaling.
    Toxicology and applied pharmacology, 2019, 05-15, Volume: 371

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; Bone Neoplasms; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Glucosides; Humans; Male; Mice, Inbred BALB C; Mice, Nude; Osteosarcoma; Proto-Oncogene Proteins c-akt; RNA, Long Noncoding; Signal Transduction; Stilbenes; Time Factors; Tumor Burden; Xenograft Model Antitumor Assays

2019
Comprehensive metabolism study of polydatin in rat plasma and urine using ultra-high performance liquid chromatography coupled with high-resolution mass spectrometry.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2019, Jun-01, Volume: 1117

    Topics: Animals; Chromatography, High Pressure Liquid; Glucosides; Male; Mass Spectrometry; Models, Molecular; Rats; Rats, Sprague-Dawley; Stilbenes

2019
Hydroxystilbene Glucosides Are Incorporated into Norway Spruce Bark Lignin.
    Plant physiology, 2019, Volume: 180, Issue:3

    Topics: Glucosides; Lignin; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Structure; Norway; Picea; Plant Bark; Resveratrol; Stilbenes

2019
Polydatin attenuates atherosclerosis in apolipoprotein E-deficient mice: Role of reverse cholesterol transport.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2019, Volume: 62

    Topics: Animals; Aorta; Apolipoproteins E; Atherosclerosis; ATP Binding Cassette Transporter 1; ATP Binding Cassette Transporter, Subfamily G, Member 1; Biological Transport; Cholesterol; Cholesterol 7-alpha-Hydroxylase; Diet, High-Fat; Fatty Liver; Foam Cells; Glucosides; Lipid Metabolism; Macrophages, Peritoneal; Male; Mice, Inbred C57BL; Mice, Knockout, ApoE; Stilbenes

2019
    Beneficial microbes, 2019, May-28, Volume: 10, Issue:5

    Topics: Animals; Bifidobacterium breve; Biological Availability; Glucosides; Hydrolysis; Isoflavones; Rats; Stilbenes

2019
Polydatin enhances the chemosensitivity of osteosarcoma cells to paclitaxel.
    Journal of cellular biochemistry, 2019, Volume: 120, Issue:10

    Topics: Apoptosis; Caspase 3; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Glucosides; Humans; Neoplasm Proteins; Osteosarcoma; Paclitaxel; Stilbenes

2019
Polydatin and I-CBP112 protects early bovine embryo against nicotinamide-induced mitochondrial dysfunction.
    Theriogenology, 2019, Volume: 134

    Topics: Acetylation; Animals; Apoptosis; Cattle; Cyclooxygenase 2; Embryo Culture Techniques; Embryonic Development; Glucosides; Histones; Membrane Potential, Mitochondrial; NF-kappa B; Niacinamide; Oxazepines; Oxidative Stress; Piperidines; Reactive Oxygen Species; Stilbenes; Tumor Suppressor Protein p53

2019
Grape Peel Extract and Resveratrol Inhibit Wrinkle Formation in Mice Model Through Activation of Nrf2/HO-1 Signaling Pathway.
    Journal of food science, 2019, Volume: 84, Issue:6

    Topics: Animals; Antioxidants; Disease Models, Animal; Female; Flavonoids; Fruit; Glucosides; Heme Oxygenase-1; Humans; Mice; Mice, Hairless; NF-E2-Related Factor 2; Plant Extracts; Resveratrol; Signal Transduction; Skin Aging; Stilbenes; Ultraviolet Rays; Vitis

2019
Evolvement of nutraceutical onion plants engineered for resveratrol biosynthetic pathway.
    Plant cell reports, 2019, Volume: 38, Issue:9

    Topics: Acyltransferases; Biosynthetic Pathways; Dietary Supplements; Glucosides; Onions; Plant Proteins; Plants, Genetically Modified; Resveratrol; Stilbenes; Vitis

2019
Protective effects of polydatin in free and nanocapsulated form on changes caused by lipopolysaccharide in hippocampal organotypic cultures.
    Pharmacological reports : PR, 2019, Volume: 71, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Cell Death; Cell Survival; Drug Compounding; Glucosides; Hippocampus; Lipopolysaccharides; Nanocapsules; Neuroprotective Agents; Rats, Sprague-Dawley; Stilbenes; Surface Properties; Tissue Culture Techniques; Toxicity Tests

2019
Polydatin-fatty acid conjugates are effective antioxidants for stabilizing omega 3-containing bulk fish oil and fish oil emulsions.
    Food chemistry, 2019, Dec-15, Volume: 301

    Topics: alpha-Tocopherol; Antioxidants; Butylated Hydroxytoluene; Emulsions; Esterification; Esters; Fatty Acids; Fatty Acids, Omega-3; Fish Oils; Fungal Proteins; Glucosides; Lipase; Oxidation-Reduction; Solvents; Stilbenes; Temperature

2019
Polydatin prevents LPS-induced acute kidney injury through inhibiting inflammatory and oxidative responses.
    Microbial pathogenesis, 2019, Volume: 137

    Topics: Acute Kidney Injury; Animals; Anti-Inflammatory Agents; Cytokines; Disease Models, Animal; Glucosides; Heme Oxygenase-1; Interleukin-1beta; Interleukin-6; Kidney; Lipopolysaccharides; Membrane Proteins; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Peptide Fragments; Signal Transduction; Stilbenes; Tumor Necrosis Factor-alpha

2019
2,3,5,4'-Tetrahydroxystilbene-2-O-β-d-glucoside attenuates MPP+/MPTP-induced neurotoxicity in vitro and in vivo by restoring the BDNF-TrkB and FGF2-Akt signaling axis and inhibition of apoptosis.
    Food & function, 2019, Sep-01, Volume: 10, Issue:9

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Apoptosis; Brain-Derived Neurotrophic Factor; Cell Survival; Dopaminergic Neurons; Drugs, Chinese Herbal; Fallopia multiflora; Fibroblast Growth Factor 2; Glucosides; Humans; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Parkinson Disease; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; Stilbenes

2019
Protective effects of polydatin on LPS-induced endometritis in mice.
    Microbial pathogenesis, 2019, Volume: 137

    Topics: Animals; Anti-Inflammatory Agents; Cytokines; Disease Models, Animal; Endometritis; Female; Glucosides; Heme Oxygenase-1; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Membrane Proteins; Mice; Mice, Inbred BALB C; NF-E2-Related Factor 2; NF-kappa B; Peroxidase; Protective Agents; Signal Transduction; Stilbenes; Tumor Necrosis Factor-alpha; Uterus; Vagina

2019
Inflammation inhibition and gut microbiota regulation by TSG to combat atherosclerosis in ApoE
    Journal of ethnopharmacology, 2020, Jan-30, Volume: 247

    Topics: Administration, Oral; Animals; Aorta; Atherosclerosis; Chemokine CCL2; Diet, High-Fat; Disease Models, Animal; Drugs, Chinese Herbal; Gastrointestinal Microbiome; Glucosides; Humans; Inflammation; Intercellular Adhesion Molecule-1; Lipoproteins, LDL; Male; Mice; Mice, Knockout, ApoE; Polygonum; Stilbenes; Triglycerides; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1

2020
The effect of light, phenylalanine and methyl jasmonate, alone or in combination, on growth and secondary metabolism in cell suspension cultures of Vitis vinifera.
    Journal of photochemistry and photobiology. B, Biology, 2019, Volume: 199

    Topics: Acetates; Biosynthetic Pathways; Catechin; Cell Culture Techniques; Cell Line; Cyclopentanes; Electric Conductivity; Flavonoids; Glucosides; Hydrogen-Ion Concentration; Light; Oxylipins; Phenols; Phenylalanine; Resveratrol; Secondary Metabolism; Stilbenes; Suspensions; Vitis

2019
Polydatin protects against lipopolysaccharide-induced endothelial barrier disruption via SIRT3 activation.
    Laboratory investigation; a journal of technical methods and pathology, 2020, Volume: 100, Issue:4

    Topics: Animals; Capillary Permeability; Cells, Cultured; Endothelium, Vascular; Glucosides; Human Umbilical Vein Endothelial Cells; Humans; Lipopolysaccharides; Mice; Protective Agents; Signal Transduction; Sirtuin 3; Stilbenes

2020
Inhibition of NET formation by polydatin protects against collagen-induced arthritis.
    International immunopharmacology, 2019, Volume: 77

    Topics: Animals; Ankle Joint; Arthritis, Experimental; Arthritis, Rheumatoid; Autoantibodies; Extracellular Traps; Glucosides; Humans; Male; Mice, Inbred DBA; Neutrophils; Protective Agents; Stilbenes

2019
Polydatin Inhibits NLRP3 Inflammasome in Dry Eye Disease by Attenuating Oxidative Stress and Inhibiting the NF-κB Pathway.
    Nutrients, 2019, Nov-15, Volume: 11, Issue:11

    Topics: Animals; Disease Models, Animal; Dry Eye Syndromes; Fallopia japonica; Glucosides; Inflammasomes; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Plant Roots; Rats; Signal Transduction; Stilbenes

2019
Shedding light on the interaction of polydatin and resveratrol with G-quadruplex and duplex DNA: a biophysical, computational and biological approach.
    International journal of biological macromolecules, 2020, May-15, Volume: 151

    Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; DNA; G-Quadruplexes; Glucosides; Humans; Models, Molecular; Molecular Conformation; Proto-Oncogene Proteins c-myc; Resveratrol; Spectrum Analysis; Stilbenes; Structure-Activity Relationship

2020
Polydatin Exerts an Antitumor Effect Through Regulating the miR-382/PD-L1 Axis in Colorectal Cancer.
    Cancer biotherapy & radiopharmaceuticals, 2020, Volume: 35, Issue:2

    Topics: Animals; Cell Culture Techniques; Colorectal Neoplasms; Drugs, Chinese Herbal; Glucosides; Humans; Male; Mice; MicroRNAs; Stilbenes; Transfection

2020
Novel polydatin-loaded chitosan nanoparticles for safe and efficient type 2 diabetes therapy: In silico, in vitro and in vivo approaches.
    International journal of biological macromolecules, 2020, Jul-01, Volume: 154

    Topics: Animals; Biomarkers; Body Weight; Chitosan; Chlorocebus aethiops; Diabetes Mellitus, Type 2; Drug Carriers; Drug Liberation; Glucosides; Hypoglycemic Agents; Male; Molecular Conformation; Molecular Dynamics Simulation; Nanoparticles; Particle Size; Rats; Rats, Wistar; Safety; Stilbenes; Vero Cells

2020
Polydatin protects H9c2 cells from hypoxia-induced injury via up-regulating long non-coding RNA DGCR5.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2019, Volume: 52, Issue:12

    Topics: Animals; Apoptosis; Cell Hypoxia; Cell Line; Cell Proliferation; Cytoprotection; Glucosides; Myocytes, Cardiac; Rats; RNA, Long Noncoding; Signal Transduction; Stilbenes; Up-Regulation

2019
Polydatin Inhibits Adipose Tissue Inflammation and Ameliorates Lipid Metabolism in High-Fat-Fed Mice.
    BioMed research international, 2019, Volume: 2019

    Topics: Adipose Tissue; Administration, Oral; Animals; Diet, High-Fat; Energy Metabolism; Glucosides; Inflammation; Lipid Metabolism; Male; Mice; Mice, Inbred C57BL; Mice, Obese; PPAR gamma; Stilbenes

2019
Micronized Palmitoylethanolamide-Polydatin Reduces the Painful Symptomatology in Patients with Interstitial Cystitis/Bladder Pain Syndrome.
    BioMed research international, 2019, Volume: 2019

    Topics: Administration, Oral; Adult; Aged; Amides; Chronic Pain; Cystitis, Interstitial; Ethanolamines; Female; Glucosides; Humans; Male; Middle Aged; Pain Measurement; Palmitic Acids; Pelvic Pain; Pilot Projects; Stilbenes; Urination

2019
Ameliorative effect of polydatin on hyperglycemia and renal injury in streptozotocin-induced diabetic rats.
    Cellular and molecular biology (Noisy-le-Grand, France), 2019, Sep-30, Volume: 65, Issue:7

    Topics: 3T3-L1 Cells; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Glucose Transporter Type 1; Glucose Transporter Type 4; Glucosides; HEK293 Cells; Humans; Hyperglycemia; Inflammation; Mice; Sodium-Glucose Transporter 1; Sodium-Glucose Transporter 2; Stilbenes

2019
Resveratrol derivative excited postsynaptic potentiation specifically via PKCβ-NMDA receptor mediation.
    Pharmacological research, 2020, Volume: 152

    Topics: Animals; Excitatory Postsynaptic Potentials; Glucosides; Hippocampus; Long-Term Potentiation; Mice, Inbred C57BL; Mice, Transgenic; Protein Kinase C beta; Receptors, N-Methyl-D-Aspartate; Stilbenes

2020
2,3,5,4'-Tetrahydroxystilbene-2-O-β-d-glucoside alleviated the acute hepatotoxicity and DNA damage in diethylnitrosamine-contaminated mice.
    Life sciences, 2020, Feb-15, Volume: 243

    Topics: Alkylating Agents; Animals; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2E1; Cytokines; Diethylnitrosamine; DNA Damage; Dose-Response Relationship, Drug; Glucosides; Inflammation Mediators; Liver; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Stilbenes

2020
The Application of (+)-Catechin and Polydatin as Functional Additives for Biodegradable Polyesters.
    International journal of molecular sciences, 2020, Jan-09, Volume: 21, Issue:2

    Topics: Biocompatible Materials; Calorimetry, Differential Scanning; Catechin; Glucosides; Oxidation-Reduction; Polyesters; Polyhydroxyalkanoates; Polyphenols; Stilbenes; Temperature; Thermogravimetry; X-Ray Diffraction

2020
[Stilbene glucoside inhibits ultraviolet radiation B-induced photoaging in human skin fibroblasts].
    Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2019, 12-25, Volume: 48, Issue:6

    Topics: Cell Proliferation; Cellular Senescence; Fibroblasts; Glucosides; Humans; Radiation-Protective Agents; Skin; Skin Aging; Stilbenes; Ultraviolet Rays

2019
In vitro and in situ study on characterization and mechanism of the intestinal absorption of 2,3,5,4'-tetrahydroxy-stilbene-2-O-β-D-glucoside.
    BMC pharmacology & toxicology, 2020, 01-22, Volume: 21, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Cell Survival; Female; Gastric Juice; Glucosides; Humans; Intestinal Absorption; Intestinal Mucosa; Intestinal Secretions; Male; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Rats, Sprague-Dawley; Stilbenes

2020
Polydatin ameliorates chemotherapy-induced cognitive impairment (chemobrain) by inhibiting oxidative stress, inflammatory response, and apoptosis in rats.
    Bioscience, biotechnology, and biochemistry, 2020, Volume: 84, Issue:6

    Topics: Animals; Antibiotics, Antineoplastic; Antioxidants; Apoptosis; Avoidance Learning; Chemotherapy-Related Cognitive Impairment; Doxorubicin; Drugs, Chinese Herbal; Fallopia japonica; Glucosides; Hippocampus; Male; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Phytotherapy; Rats; Rats, Sprague-Dawley; Signal Transduction; Spatial Memory; Stilbenes; Up-Regulation

2020
Tetrahydroxystilbene Glucoside Ameliorates Infrasound-Induced Central Nervous System (CNS) Injury by Improving Antioxidant and Anti-Inflammatory Capacity.
    Oxidative medicine and cellular longevity, 2020, Volume: 2020

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Central Nervous System; Cytokines; Disease Models, Animal; Glucosides; Inflammation; Male; Mice; Stilbenes; Ultrasonic Waves

2020
Polydatin attenuates cadmium-induced oxidative stress via stimulating SOD activity and regulating mitochondrial function in Musca domestica larvae.
    Chemosphere, 2020, Volume: 248

    Topics: Animals; Cadmium; Glucosides; Houseflies; Humans; Larva; Malondialdehyde; Membrane Potential, Mitochondrial; Mitochondria; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Stilbenes; Superoxide Dismutase

2020
2,3,5,4'-Tetrahydroxystilbene-2-O-β-d-glucoside Restores BDNF-TrkB and FGF2-Akt Signaling Axis to Attenuate Stress-induced Depression.
    Neuroscience, 2020, 03-15, Volume: 430

    Topics: Animals; Brain-Derived Neurotrophic Factor; Depression; Fibroblast Growth Factor 2; Glucosides; Hippocampus; Mice; Proto-Oncogene Proteins c-akt; Signal Transduction; Stilbenes; Stress, Psychological

2020
P2X7 receptor-targeted regulation by tetrahydroxystilbene glucoside in alcoholic hepatosteatosis: A new strategy towards macrophage-hepatocyte crosstalk.
    British journal of pharmacology, 2020, Volume: 177, Issue:12

    Topics: Adenosine Triphosphate; Animals; Glucosides; Hepatocytes; Interleukin-1beta; Macrophages; Mice; Mice, Inbred C57BL; Receptors, Purinergic P2X7; Stilbenes

2020
Role of Parkin-mediated mitophagy in the protective effect of polydatin in sepsis-induced acute kidney injury.
    Journal of translational medicine, 2020, 03-04, Volume: 18, Issue:1

    Topics: Acute Kidney Injury; Animals; Glucosides; Mice; Mitophagy; Rats; Sepsis; Stilbenes; Ubiquitin-Protein Ligases

2020
Polydatin induces apoptosis and autophagy via STAT3 signaling in human osteosarcoma MG-63 cells.
    Journal of natural medicines, 2020, Volume: 74, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; Autophagy; Bone Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Glucosides; Humans; Osteosarcoma; Phosphorylation; Signal Transduction; STAT3 Transcription Factor; Stilbenes

2020
Polydatin promotes the neuronal differentiation of bone marrow mesenchymal stem cells in vitro and in vivo: Involvement of Nrf2 signalling pathway.
    Journal of cellular and molecular medicine, 2020, Volume: 24, Issue:9

    Topics: Animals; Axons; Cell Differentiation; Cell Shape; Cell Survival; Glucosides; Male; Mesenchymal Stem Cells; Mice, Inbred C57BL; Motor Activity; Nerve Regeneration; Neurons; NF-E2-Related Factor 2; Signal Transduction; Spinal Cord Injuries; Stilbenes

2020
PARP1 might enhance the therapeutic effect of tetrahydroxystilbene glucoside in traumatic brain injury via inhibition of Ras/JNK signalling pathway.
    Folia neuropathologica, 2020, Volume: 58, Issue:1

    Topics: Adult; Animals; Brain Injuries, Traumatic; Glucosides; Humans; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Middle Aged; Oxidative Stress; Poly (ADP-Ribose) Polymerase-1; ras Proteins; Reactive Oxygen Species; Stilbenes

2020
Tetrahydroxy stilbene glycoside alleviated inflammatory damage by mitophagy via AMPK related PINK1/Parkin signaling pathway.
    Biochemical pharmacology, 2020, Volume: 177

    Topics: Alzheimer Disease; AMP-Activated Protein Kinases; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Anti-Inflammatory Agents; Cell Line, Tumor; Cognitive Dysfunction; Disease Models, Animal; Gene Expression Regulation; Glucosides; Humans; Inflammasomes; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microglia; Mitochondria; Mitophagy; Neurons; Neuroprotective Agents; NLR Family, Pyrin Domain-Containing 3 Protein; Primary Cell Culture; Protein Kinases; RNA, Small Interfering; Signal Transduction; Stilbenes; Ubiquitin-Protein Ligases

2020
2,3,5,4'-tetrahydroxystilbence-2-O-β-D-glucoside attenuates hepatic steatosis via IKKβ/NF-κB and Keap1-Nrf2 pathways in larval zebrafish.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020, Volume: 127

    Topics: Animals; Cholesterol, Dietary; Disease Models, Animal; Glucosides; I-kappa B Kinase; Kelch-Like ECH-Associated Protein 1; Lipid Metabolism; NF-E2-Related Factor 2; NF-kappa B; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Signal Transduction; Stilbenes; Zebrafish; Zebrafish Proteins

2020
Polydatin Alleviates Septic Myocardial Injury by Promoting SIRT6-Mediated Autophagy.
    Inflammation, 2020, Volume: 43, Issue:3

    Topics: Animals; Autophagy; Cardiomyopathies; Cell Line; Glucosides; Lipopolysaccharides; Male; Myocardium; Rats; Rats, Sprague-Dawley; Sepsis; Sirtuins; Stilbenes

2020
Effect of Polydatin on Neurological Function and the Nrf2 Pathway during Intracerebral Hemorrhage.
    Journal of molecular neuroscience : MN, 2020, Volume: 70, Issue:9

    Topics: Animals; Antioxidants; Brain; Cerebral Hemorrhage; Glucosides; Heme Oxygenase (Decyclizing); Kelch-Like ECH-Associated Protein 1; Male; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Oxidative Stress; Rats; Rats, Wistar; Stilbenes

2020
Polydatin improves osteogenic differentiation of human bone mesenchymal stem cells by stimulating TAZ expression via BMP2-Wnt/β-catenin signaling pathway.
    Stem cell research & therapy, 2020, 05-27, Volume: 11, Issue:1

    Topics: Acyltransferases; beta Catenin; Bone Morphogenetic Protein 2; Cell Differentiation; Cells, Cultured; Glucosides; Humans; Mesenchymal Stem Cells; Osteogenesis; Stilbenes; Wnt Signaling Pathway

2020
Percutaneous absorption of resveratrol and its oligomers to relieve psoriasiform lesions: In silico, in vitro and in vivo evaluations.
    International journal of pharmaceutics, 2020, Jul-30, Volume: 585

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Benzofurans; Chemistry, Pharmaceutical; Chemokines; Cytokines; Flavonoids; Glucosides; Inflammation Mediators; Keratinocytes; Mice; Phenols; Plant Extracts; Psoriasis; Resveratrol; Skin Absorption; Stilbenes; Swine

2020
2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside induces autophagy of liver by activating PI3K/Akt and Erk pathway in prediabetic rats.
    BMC complementary medicine and therapies, 2020, Jun-08, Volume: 20, Issue:1

    Topics: Animals; Autophagy; Fallopia multiflora; Glucosides; Liver; Male; MAP Kinase Signaling System; Molecular Structure; Phosphatidylinositol 3-Kinases; Prediabetic State; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Stilbenes

2020
High-throughput screening suggests glutathione synthetase as an anti-tumor target of polydatin using human proteome chip.
    International journal of biological macromolecules, 2020, Oct-15, Volume: 161

    Topics: Antineoplastic Agents; Cell Line, Tumor; Drug Screening Assays, Antitumor; Drugs, Chinese Herbal; Glucosides; Glutathione Synthase; High-Throughput Screening Assays; Humans; Proteome; Proteomics; Stilbenes

2020
Localization of (+)-Catechin in
    Molecules (Basel, Switzerland), 2020, Jun-26, Volume: 25, Issue:12

    Topics: Ascomycota; Catechin; Gas Chromatography-Mass Spectrometry; Glucosides; Microscopy, Electron, Transmission; Phloem; Picea; Plant Bark; Plant Diseases; Plant Extracts; Spectrometry, Mass, Secondary Ion; Stilbenes; Tissue Distribution

2020
Otoprotective Effect of 2,3,4',5-Tetrahydroxystilbene-2-
    Molecules (Basel, Switzerland), 2020, Jul-06, Volume: 25, Issue:13

    Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Cell Line; Cell Survival; Fallopia multiflora; Gentamicins; Glucosides; L-Lactate Dehydrogenase; Membrane Potential, Mitochondrial; Mice; Mitochondria; Ototoxicity; Reactive Oxygen Species; Stilbenes; Superoxide Dismutase

2020
SIRT1 Activation by Polydatin Alleviates Oxidative Damage and Elevates Mitochondrial Biogenesis in Experimental Diabetic Neuropathy.
    Cellular and molecular neurobiology, 2021, Volume: 41, Issue:7

    Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Glucosides; Mice; Mitochondria; Organelle Biogenesis; Oxidative Stress; Sirtuin 1; Stilbenes; Streptozocin

2021
Pharmacological and metagenomics evidence of polysaccharide from Polygonum multiflorum in the alleviation of insulin resistance.
    International journal of biological macromolecules, 2020, Dec-01, Volume: 164

    Topics: AMP-Activated Protein Kinases; Animals; Fallopia multiflora; Fatty Acids, Volatile; Feces; Gastrointestinal Microbiome; Glucosides; Insulin; Insulin Resistance; Liver; Male; Metagenomics; Polysaccharides; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; RNA, Ribosomal, 16S; Signal Transduction; Stilbenes

2020
NMR-Based Metabonomic Study Reveals Intervention Effects of Polydatin on Potassium Oxonate-Induced Hyperuricemia in Rats.
    Oxidative medicine and cellular longevity, 2020, Volume: 2020

    Topics: Animals; Blood Urea Nitrogen; Creatinine; Disease Models, Animal; Drugs, Chinese Herbal; Glucosides; Humans; Hyperuricemia; Kidney; Male; Metabolomics; Oxonic Acid; Rats; Rats, Sprague-Dawley; Stilbenes; Uric Acid

2020
Polydatin attenuates renal fibrosis in diabetic mice through regulating the Cx32-Nox4 signaling pathway.
    Acta pharmacologica Sinica, 2020, Volume: 41, Issue:12

    Topics: Animals; Connexins; Diabetes Mellitus, Experimental; Fibronectins; Fibrosis; Gap Junction beta-1 Protein; Glucosides; Intercellular Adhesion Molecule-1; Kidney; Male; Mice, Inbred C57BL; NADPH Oxidase 4; Oxidative Stress; Rats, Sprague-Dawley; Signal Transduction; Stilbenes; Ubiquitination

2020
Polydatin executes anticancer effects against glioblastoma multiforme by inhibiting the EGFR-AKT/ERK1/2/STAT3-SOX2/Snail signaling pathway.
    Life sciences, 2020, Oct-01, Volume: 258

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; ErbB Receptors; Glioblastoma; Glucosides; Humans; MAP Kinase Signaling System; Mice, Inbred BALB C; Mice, Nude; Proto-Oncogene Proteins c-akt; Signal Transduction; Snail Family Transcription Factors; SOXB1 Transcription Factors; STAT3 Transcription Factor; Stilbenes

2020
Polydatin alleviates parkinsonism in MPTP-model mice by enhancing glycolysis in dopaminergic neurons.
    Neurochemistry international, 2020, Volume: 139

    Topics: Animals; Dopaminergic Neurons; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Glucosides; Glycolysis; Male; Mice; Mice, Inbred BALB C; Parkinsonian Disorders; Stilbenes

2020
2,3,5,4'-Tetrahydroxystilbene-2-O-β-d-glucoside promotes the effects of dental pulp stem cells on rebuilding periodontal tissues in experimental periodontal defects.
    Journal of periodontology, 2021, Volume: 92, Issue:2

    Topics: Animals; Dental Pulp; Glucosides; Male; Rats; Rats, Sprague-Dawley; Stem Cells; Stilbenes; Vascular Endothelial Growth Factor A; X-Ray Microtomography

2021
Establishment and validation of a drug-target microarray for SARS-CoV-2.
    Biochemical and biophysical research communications, 2020, 09-10, Volume: 530, Issue:1

    Topics: Antiviral Agents; Betacoronavirus; Biological Products; Chlorogenic Acid; Coronavirus Infections; COVID-19; Diterpenes; Drug Discovery; Drugs, Chinese Herbal; Glucosides; HEK293 Cells; Humans; Molecular Docking Simulation; Molecular Targeted Therapy; Pandemics; Pneumonia, Viral; Protein Array Analysis; Proteins; SARS-CoV-2; Stilbenes; Viral Proteins

2020
Multiflorumisides HK, stilbene glucosides isolated from Polygonum multiflorum and their in vitro PTP1B inhibitory activities.
    Fitoterapia, 2020, Volume: 146

    Topics: China; Enzyme Inhibitors; Fallopia multiflora; Glucosides; Molecular Structure; Phytochemicals; Plant Roots; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Stilbenes

2020
Selective separation and purification of polydatin by molecularly imprinted polymers from the extract of Polygoni Cuspidati Rhizoma et Radix, rats' plasma and urine.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2020, Nov-01, Volume: 1156

    Topics: Animals; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Fallopia japonica; Glucosides; Limit of Detection; Linear Models; Male; Molecular Imprinting; Molecularly Imprinted Polymers; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Solid Phase Extraction; Stilbenes

2020
Control over Polymorph Formation of Polydatin in Binary Solvent System and Structural Characterization.
    Journal of pharmaceutical and biomedical analysis, 2020, Oct-25, Volume: 190

    Topics: Calorimetry, Differential Scanning; Crystallization; Crystallography, X-Ray; Glucosides; Solvents; Spectroscopy, Fourier Transform Infrared; Stilbenes; X-Ray Diffraction

2020
2,3,5,4'-Tetrahydroxy-stilbene-2-
    Pharmaceutical biology, 2020, Volume: 58, Issue:1

    Topics: Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Cell Line; Cell Survival; Chemical and Drug Induced Liver Injury; Core Binding Factor Alpha 2 Subunit; Glucosides; Hepatocytes; Humans; MicroRNAs; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Stilbenes; TOR Serine-Threonine Kinases

2020
Tetrahydroxystilbene glucoside alleviates angiotensin II induced HUVEC senescence via SIRT1.
    Canadian journal of physiology and pharmacology, 2021, Volume: 99, Issue:4

    Topics: Angiotensin II; Cellular Senescence; Glucosides; Human Umbilical Vein Endothelial Cells; Humans; Signal Transduction; Sirtuin 1; Stilbenes

2021
2,3,5,4'-tetrahydoxystilbene-2-O-β-D-glucoside eliminates staurosporine-induced cytotoxicity by restoring BDNF-TrkB/Akt signaling axis.
    International journal of medical sciences, 2020, Volume: 17, Issue:14

    Topics: Animals; Animals, Newborn; Apoptosis; Brain-Derived Neurotrophic Factor; Carbazoles; Cell Survival; Cells, Cultured; Chromones; Fallopia multiflora; Glucosides; Hippocampus; Indole Alkaloids; Morpholines; Neurons; Neuroprotective Agents; Primary Cell Culture; Proto-Oncogene Proteins c-akt; Rats; Receptor, trkB; Signal Transduction; Staurosporine; Stilbenes

2020
Polydatin Attenuates 14.1 MeV Neutron-Induced Injuries via Regulating the Apoptosis and Antioxidative Pathways and Improving the Hematopoiesis of Mice.
    Oxidative medicine and cellular longevity, 2020, Volume: 2020

    Topics: Animals; Antioxidants; Apoptosis; Body Weight; Bone Marrow Cells; Glucosides; Hematopoiesis; Heme Oxygenase-1; Kelch-Like ECH-Associated Protein 1; Lung; Male; Mice, Inbred BALB C; Neutrons; Radiation, Ionizing; Sirtuin 1; Spleen; Stilbenes; Survival Analysis

2020
Evaluation of the potency of FDA-approved drugs on wild type and mutant SARS-CoV-2 helicase (Nsp13).
    International journal of biological macromolecules, 2020, Nov-15, Volume: 163

    Topics: Adenosine Monophosphate; Amino Acid Sequence; Betacoronavirus; Binding Sites; Computer Simulation; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Drug Approval; Drug Repositioning; Enzyme Inhibitors; Folic Acid; Genome, Viral; Glucosides; Humans; Methyltransferases; Molecular Docking Simulation; Mutation; Pandemics; Pneumonia, Viral; RNA Helicases; SARS-CoV-2; Stilbenes; Vidarabine; Viral Nonstructural Proteins

2020
Polydatin attenuates Mycoplasma gallisepticum (HS strain)-induced inflammation injury via inhibiting the TLR6/ MyD88/NF-κB pathway.
    Microbial pathogenesis, 2020, Volume: 149

    Topics: Animals; Chick Embryo; Chickens; Glucosides; Inflammation; Mycoplasma gallisepticum; Myeloid Differentiation Factor 88; NF-kappa B; Stilbenes; Toll-Like Receptor 6; Tumor Necrosis Factor-alpha

2020
Polydatin inhibits ZEB1-invoked epithelial-mesenchymal transition in fructose-induced liver fibrosis.
    Journal of cellular and molecular medicine, 2020, Volume: 24, Issue:22

    Topics: Active Transport, Cell Nucleus; Animals; Cadherins; Collagen Type I; Collagen Type I, alpha 1 Chain; Epithelial-Mesenchymal Transition; Fructose; Glucosides; Liver Cirrhosis; Male; MicroRNAs; Rats; Rats, Sprague-Dawley; Signal Transduction; Stilbenes; Transforming Growth Factor beta1; Zinc Finger E-box-Binding Homeobox 1

2020
Tetrahydroxystilbene glucoside protects against LPS-induced endothelial dysfunction via inhibiting RhoA/ROCK signaling and F-actin remodeling.
    General physiology and biophysics, 2020, Volume: 39, Issue:5

    Topics: Actins; Cells, Cultured; Glucosides; Human Umbilical Vein Endothelial Cells; Humans; Lipopolysaccharides; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Stilbenes

2020
Screening of an Endophyte Transforming Polydatin to Resveratrol from
    Molecules (Basel, Switzerland), 2020, Oct-20, Volume: 25, Issue:20

    Topics: Antioxidants; Chromatography, High Pressure Liquid; Endophytes; Glucosides; Mass Spectrometry; Polygonaceae; Resveratrol; Rhizome; RNA, Ribosomal, 16S; Stilbenes

2020
Polydatin and its potential protective effect on COVID-19.
    Clinical nutrition (Edinburgh, Scotland), 2020, Volume: 39, Issue:12

    Topics: COVID-19 Drug Treatment; Dietary Supplements; Drugs, Chinese Herbal; Glucosides; Humans; SARS-CoV-2; Stilbenes

2020
Protective Effect of Polydatin on Jejunal Mucosal Integrity, Redox Status, Inflammatory Response, and Mitochondrial Function in Intrauterine Growth-Retarded Weanling Piglets.
    Oxidative medicine and cellular longevity, 2020, Volume: 2020

    Topics: Amine Oxidase (Copper-Containing); AMP-Activated Protein Kinases; Animals; Dietary Supplements; DNA, Mitochondrial; Energy Metabolism; Fetal Growth Retardation; Glucosides; Glutathione; Intestinal Mucosa; Jejunum; Lactic Acid; Mitochondria; Protective Agents; Signal Transduction; Sirtuin 1; Stilbenes; Superoxide Dismutase; Swine; Tumor Necrosis Factor-alpha; Up-Regulation

2020
Polydatin enhances glomerular podocyte autophagy homeostasis by improving Nrf2-dependent antioxidant capacity in fructose-fed rats.
    Molecular and cellular endocrinology, 2021, 01-15, Volume: 520

    Topics: Adenosine Triphosphate; Adenylate Kinase; Animals; Antioxidants; Autophagy; Feeding Behavior; Fructose; Glucosides; Homeostasis; Humans; Male; Mechanistic Target of Rapamycin Complex 1; NF-E2-Related Factor 2; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Podocytes; Proteinuria; Rats, Sprague-Dawley; Signal Transduction; Stilbenes

2021
One-pot method based on deep eutectic solvent for extraction and conversion of polydatin to resveratrol from Polygonum cuspidatum.
    Food chemistry, 2021, May-01, Volume: 343

    Topics: Chemical Fractionation; Fallopia japonica; Glucosides; Hydrolysis; Resveratrol; Solvents; Stilbenes

2021
Polydatin alleviates high-fat diet induced atherosclerosis in apolipoprotein E-deficient mice by autophagic restoration.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2021, Volume: 81

    Topics: Animals; Aorta; Apolipoproteins E; Atherosclerosis; Autophagy; Diet, High-Fat; Glucosides; Male; Mice, Knockout, ApoE; Molecular Docking Simulation; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Plaque, Atherosclerotic; Proto-Oncogene Proteins c-akt; Stilbenes; TOR Serine-Threonine Kinases

2021
Promotive effects of tetrahydroxystilbene glucoside on the differentiation of neural stem cells from the mesencephalon into dopaminergic neurons.
    Neuroscience letters, 2021, 01-18, Volume: 742

    Topics: Animals; Cell Differentiation; Cells, Cultured; Dopaminergic Neurons; Female; Glucosides; Mesencephalon; Mice; Mice, Inbred BALB C; Neural Stem Cells; Parkinson Disease; Pregnancy; Stilbenes; Wnt Signaling Pathway

2021
Polydatin mitigates pancreatic β-cell damage through its antioxidant activity.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 133

    Topics: Animals; Antioxidants; Apoptosis; Blood Glucose; Cell Line; Cell Survival; Diabetes Mellitus, Experimental; Glucosides; Hypoglycemic Agents; Inflammation Mediators; Insulin; Insulin-Secreting Cells; Lipid Peroxidation; Lipids; Male; Oxidative Stress; Rats, Wistar; Stilbenes

2021
Cardioprotective effects of polydatin against myocardial injury in diabetic rats via inhibition of NADPH oxidase and NF-κB activities.
    BMC complementary medicine and therapies, 2020, Dec-11, Volume: 20, Issue:1

    Topics: Animals; Cardiomyopathies; Cell Line; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Drug Evaluation, Preclinical; Drugs, Chinese Herbal; Fallopia japonica; Glucosides; Heart; Male; Myocardium; NADPH Oxidases; NF-kappa B; Oxidative Stress; Rats, Sprague-Dawley; Stilbenes

2020
Polydatin and polydatin-loaded chitosan nanoparticles attenuate diabetic cardiomyopathy in rats.
    Journal of molecular histology, 2021, Volume: 52, Issue:2

    Topics: Animals; Antioxidants; Chitosan; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Glucosides; Glycated Hemoglobin; Immunohistochemistry; Male; Nanoparticles; Oxidative Stress; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Stilbenes

2021
Polydatin-Induced Direct and Bystander Effects in A549 Lung Cancer Cell Line.
    Nutrition and cancer, 2022, Volume: 74, Issue:1

    Topics: A549 Cells; Apoptosis; Bystander Effect; Cell Line, Tumor; Cell Proliferation; Glucosides; Humans; Lung Neoplasms; Stilbenes

2022
Polydatin inhibits LPS-induced inflammatory response in BV2 microglia by disrupting the formation of lipid rafts.
    Immunopharmacology and immunotoxicology, 2021, Volume: 43, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Glucosides; Inflammation Mediators; Lipopolysaccharides; Membrane Microdomains; Mice; Microglia; Stilbenes

2021
Polydatin Beneficial Effects in Zebrafish Larvae Undergoing Multiple Stress Types.
    International journal of environmental research and public health, 2021, 01-27, Volume: 18, Issue:3

    Topics: Animals; Glucosides; Larva; Oxidative Stress; Stilbenes; Zebrafish

2021
Characterization of the metabolites of
    Journal of Asian natural products research, 2022, Volume: 24, Issue:2

    Topics: Animals; Chromatography, High Pressure Liquid; Chromatography, Liquid; Dogs; Glucosides; Haplorhini; Molecular Structure; Stilbenes

2022
Polydatin Protects Bovine Mammary Epithelial Cells Against Zearalenone-Induced Apoptosis By Inhibiting Oxidative Responses and Endoplasmic Reticulum Stress.
    Toxins, 2021, 02-05, Volume: 13, Issue:2

    Topics: Animals; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; Cattle; Cell Line; Cytoprotection; Endoplasmic Reticulum Stress; Epithelial Cells; Female; Glucosides; Mammary Glands, Animal; Oxidative Stress; Reactive Oxygen Species; Stilbenes; Zearalenone

2021
SIRT1 attenuates sepsis-induced acute kidney injury via Beclin1 deacetylation-mediated autophagy activation.
    Cell death & disease, 2021, 02-26, Volume: 12, Issue:2

    Topics: Acetylation; Acute Kidney Injury; Animals; Autophagy; Beclin-1; Cell Line; Disease Models, Animal; Enzyme Activation; Enzyme Activators; Glucosides; Humans; Kidney Tubules, Proximal; Male; Mice, Inbred C57BL; Resveratrol; Sepsis; Signal Transduction; Sirtuin 1; Stilbenes; Time Factors

2021
[Heterologous expression of a novel β-glucosidase BglD2 and its application in polydatin-hydrolyzing].
    Sheng wu gong cheng xue bao = Chinese journal of biotechnology, 2021, Feb-25, Volume: 37, Issue:2

    Topics: beta-Glucosidase; Enzyme Stability; Glucose; Glucosides; Hydrogen-Ion Concentration; Stilbenes; Substrate Specificity; Temperature; Xylose

2021
Tetrahydroxystilbene glycoside improves endothelial dysfunction and hypertension in obese rats: The role of omentin-1.
    Biochemical pharmacology, 2021, Volume: 186

    Topics: Animals; Cytokines; Endothelium, Vascular; Glucosides; GPI-Linked Proteins; Humans; Hypertension; Lectins; Male; Mice; Mice, Knockout; Rats; Rats, Zucker; Stilbenes

2021
Development of an UHPLC-diode arrays detector (DAD) method for the analysis of polydatin in human plasma.
    Journal of pharmaceutical and biomedical analysis, 2021, May-10, Volume: 198

    Topics: Chromatography, High Pressure Liquid; Glucosides; Humans; Plasma; Reproducibility of Results; Stilbenes

2021
Comparison of Ferroptosis-Inhibitory Mechanisms between Ferrostatin-1 and Dietary Stilbenes (Piceatannol and Astringin).
    Molecules (Basel, Switzerland), 2021, Feb-19, Volume: 26, Issue:4

    Topics: Animals; Antioxidants; Cyclic N-Oxides; Cyclohexylamines; Diet; Ferroptosis; Glucosides; Imidazoles; Inhibitory Concentration 50; Male; Mesenchymal Stem Cells; Models, Molecular; Phenylenediamines; Piperazines; Rats, Sprague-Dawley; Static Electricity; Stilbenes

2021
First Total Synthesis of Gaylussacin and Its Stilbene Derivatives.
    Journal of natural products, 2021, 04-23, Volume: 84, Issue:4

    Topics: Glucosides; Glycosides; Glycosylation; Molecular Structure; Stilbenes

2021
2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-glucoside, a major bioactive component from Polygoni multiflori Radix (Heshouwu) suppresses DSS induced acute colitis in BALb/c mice by modulating gut microbiota.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 137

    Topics: Animals; Anti-Inflammatory Agents; Colitis, Ulcerative; Colon; Cytokines; Dextran Sulfate; DNA, Bacterial; Feces; Gastrointestinal Microbiome; Glucosides; Male; Mice; Mice, Inbred BALB C; Plant Extracts; Plants, Medicinal; RNA, Ribosomal, 16S; Stilbenes; Tight Junction Proteins

2021
Polydatin Prevents Calcium Pyrophosphate Crystal-Induced Arthritis in Mice.
    Nutrients, 2021, Mar-13, Volume: 13, Issue:3

    Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Calcium Pyrophosphate; Chemokine CXCL1; Glucosides; Interleukin-1beta; Mice; Mice, Inbred BALB C; Stilbenes; Tarsus, Animal

2021
Hepatoprotective Effects of Polydatin-Loaded Chitosan Nanoparticles in Diabetic Rats: Modulation of Glucose Metabolism, Oxidative Stress, and Inflammation Biomarkers.
    Biochemistry. Biokhimiia, 2021, Volume: 86, Issue:2

    Topics: Animals; Chitosan; Diabetes Mellitus, Experimental; Glucose; Glucosides; Inflammation; Lipid Peroxidation; Liver; Male; Metformin; Nanoparticles; Niacinamide; Oxidative Stress; Protective Agents; Rats; Rats, Wistar; Stilbenes; Streptozocin

2021
Polydatin alleviates traumatic brain injury: Role of inhibiting ferroptosis.
    Biochemical and biophysical research communications, 2021, 06-04, Volume: 556

    Topics: Animals; Brain; Brain Injuries, Traumatic; Cell Line; Cell Survival; Disease Models, Animal; Ferroptosis; Glucosides; Hemin; Iron; Male; Mice; Mice, Inbred C57BL; Neurons; Neuroprotection; Neuroprotective Agents; Phospholipid Hydroperoxide Glutathione Peroxidase; Stilbenes

2021
Tetrahydroxy Stilbene Glucoside Ameliorates Cognitive Impairments and Pathology in APP/PS1 Transgenic Mice.
    Current medical science, 2021, Volume: 41, Issue:2

    Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Cognitive Dysfunction; Glucosides; Hippocampus; Memory Disorders; Mice, Transgenic; Peptide Fragments; Presenilin-1; Stilbenes

2021
Polydatin and COVID-19.
    Clinical nutrition (Edinburgh, Scotland), 2022, Volume: 41, Issue:12

    Topics: COVID-19; Glucosides; Humans; Stilbenes

2022
Polydatin Attenuates OGD/R-Induced Neuronal Injury and Spinal Cord Ischemia/Reperfusion Injury by Protecting Mitochondrial Function via Nrf2/ARE Signaling Pathway.
    Oxidative medicine and cellular longevity, 2021, Volume: 2021

    Topics: Animals; Female; Glucosides; Humans; Male; Mice; Mitochondria; NF-E2-Related Factor 2; Reperfusion Injury; Signal Transduction; Spinal Cord; Spinal Cord Ischemia; Stilbenes

2021
Polydatin has anti-inflammatory and antioxidant effects in LPS-induced macrophages and improves DSS-induced mice colitis.
    Immunity, inflammation and disease, 2021, Volume: 9, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Colitis; Glucosides; Lipopolysaccharides; Macrophages; Mice; NF-kappa B; Stilbenes

2021
Glucose-6-phosphate dehydrogenase inhibitor for treatment of severe COVID-19: Polydatin.
    Clinical nutrition ESPEN, 2021, Volume: 43

    Topics: Anti-Inflammatory Agents; Antioxidants; COVID-19; COVID-19 Drug Treatment; Glucosephosphate Dehydrogenase; Glucosides; Humans; Inflammation; Lung; Magnoliopsida; Oxidative Stress; Pandemics; Phytotherapy; Plant Extracts; Resveratrol; SARS-CoV-2; Stilbenes

2021
Polydatin protects Schwann cells from methylglyoxal induced cytotoxicity and promotes crushed sciatic nerves regeneration of diabetic rats.
    Phytotherapy research : PTR, 2021, Volume: 35, Issue:8

    Topics: Animals; Cells, Cultured; Diabetes Mellitus, Experimental; Glucosides; Kelch-Like ECH-Associated Protein 1; Nerve Crush; NF-E2-Related Factor 2; Pyruvaldehyde; Rats; Schwann Cells; Sciatic Nerve; Stilbenes

2021
Polydatin alleviates severe traumatic brain injury induced acute lung injury by inhibiting S100B mediated NETs formation.
    International immunopharmacology, 2021, Volume: 98

    Topics: Acute Lung Injury; Animals; Brain Injuries, Traumatic; Disease Models, Animal; Extracellular Traps; Glucosides; Humans; Lung; Male; Oxidative Stress; Rats; S100 Calcium Binding Protein beta Subunit; Stilbenes

2021
The Protective Effect of Tetrahydroxystilbene Glucoside on High Glucose-Induced Injury in Human Umbilical Vein Endothelial Cells through the PI3K/Akt/eNOS Pathway and Regulation of Bcl-2/Bax.
    Journal of vascular research, 2021, Volume: 58, Issue:5

    Topics: Apoptosis; bcl-2-Associated X Protein; Cells, Cultured; Glucose; Glucosides; Human Umbilical Vein Endothelial Cells; Humans; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinase; Phosphorylation; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Signal Transduction; Stilbenes

2021
Neuroprotection against 1-Methyl-4-phenylpyridinium-induced cytotoxicity by naturally occurring polydatin through activation of transcription factor MEF2D.
    Neuroreport, 2021, 08-11, Volume: 32, Issue:12

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Animals, Newborn; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Glucosides; Herbicides; MEF2 Transcription Factors; Neuroprotective Agents; PC12 Cells; Rats; Rats, Sprague-Dawley; Stilbenes

2021
Investigation of toxicity attenuation mechanism of tetrahydroxy stilbene glucoside in Polygonum multiflorum Thunb. by Ganoderma lucidum.
    Journal of ethnopharmacology, 2021, Nov-15, Volume: 280

    Topics: Biotransformation; Cell Line; Fallopia multiflora; Fermentation; Glucosides; Hepatocytes; Humans; Peroxidases; Reishi; Stilbenes

2021
Polydatin attenuates hepatic stellate cell proliferation and liver fibrosis by suppressing sphingosine kinase 1.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020, Volume: 130

    Topics: Animals; Apoptosis; Biomarkers; Cell Line, Transformed; Cell Proliferation; Disease Models, Animal; Enzyme Inhibitors; Glucosides; Hepatic Stellate Cells; Humans; Liver Cirrhosis; Mice; Phosphotransferases (Alcohol Group Acceptor); Signal Transduction; Stilbenes

2020
Polydatin Induces Differentiation and Radiation Sensitivity in Human Osteosarcoma Cells and Parallel Secretion through Lipid Metabolite Secretion.
    Oxidative medicine and cellular longevity, 2021, Volume: 2021

    Topics: Cell Differentiation; Drugs, Chinese Herbal; Glucosides; Humans; Lipid Metabolism; Osteosarcoma; Stilbenes

2021
Polydatin gold nanoparticles potentiate antitumor effect of doxorubicin in Ehrlich ascites carcinoma-bearing mice.
    Journal of biochemical and molecular toxicology, 2021, Volume: 35, Issue:10

    Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Disease Models, Animal; Doxorubicin; Drug Synergism; Drugs, Chinese Herbal; Fallopia japonica; Female; Glucosides; Gold; Heart; Metal Nanoparticles; Mice; Nanoparticle Drug Delivery System; Phytochemicals; Phytotherapy; Protective Agents; Stilbenes; Treatment Outcome; Tumor Burden

2021
Interference of Polydatin/Resveratrol in the ACE2:Spike Recognition during COVID-19 Infection. A Focus on Their Potential Mechanism of Action through Computational and Biochemical Assays.
    Biomolecules, 2021, 07-16, Volume: 11, Issue:7

    Topics: Angiotensin-Converting Enzyme 2; COVID-19; COVID-19 Drug Treatment; Drug Discovery; Drugs, Chinese Herbal; Enzyme Inhibitors; Glucosides; Host-Pathogen Interactions; Humans; Molecular Docking Simulation; Protein Binding; Resveratrol; SARS-CoV-2; Spike Glycoprotein, Coronavirus; Stilbenes

2021
Renovation of Intestinal Barrier by Polydatin in Experimentally Induced Ulcerative Colitis: Comparative Ultrastructural Study with L-Carnosine.
    Cells, tissues, organs, 2021, Volume: 210, Issue:4

    Topics: Animals; Carnosine; Colitis, Ulcerative; Colon; Disease Models, Animal; Glucosides; Humans; Rats; Stilbenes

2021
Comparison of the Effects of Resveratrol and Its Derivatives on the Radiation Response of MCF-7 Breast Cancer Cells.
    International journal of molecular sciences, 2021, Sep-01, Volume: 22, Issue:17

    Topics: Breast Neoplasms; Female; Glucosides; Humans; MCF-7 Cells; Radiation Tolerance; Radiation, Ionizing; Resveratrol; Stilbenes

2021
Co-Crystals of Resveratrol and Polydatin with L-Proline: Crystal Structures, Dissolution Properties, and In Vitro Cytotoxicities.
    Molecules (Basel, Switzerland), 2021, Sep-21, Volume: 26, Issue:18

    Topics: A549 Cells; Cell Survival; Crystallization; Drug Compounding; Glucosides; HEK293 Cells; Humans; In Vitro Techniques; Molecular Conformation; Proline; Resveratrol; Solubility; Stilbenes

2021
Neuroprotective Effects of Tetrahydroxystilbene Glucoside against Rotenone-Induced Toxicity in PC12 Cells.
    Biological & pharmaceutical bulletin, 2022, Jan-01, Volume: 45, Issue:1

    Topics: Animals; Apoptosis; Glucosides; Neuroprotective Agents; PC12 Cells; Rats; Reactive Oxygen Species; Rotenone; Stilbenes

2022
Development of a novel UPLC-MS/MS method for the simultaneously quantification of polydatin and resveratrol in plasma: Application to a pharmacokinetic study in rats.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2021, Nov-15, Volume: 1185

    Topics: Animals; Chromatography, High Pressure Liquid; Feces; Glucosides; Male; Plasma; Rats; Resveratrol; Stilbenes; Tandem Mass Spectrometry

2021
Effective inhibition of coronavirus replication by
    Frontiers in bioscience (Landmark edition), 2021, 10-30, Volume: 26, Issue:10

    Topics: Antiviral Agents; Cell Line, Tumor; Cell Survival; COVID-19; Drugs, Chinese Herbal; Fallopia japonica; Glucosides; HEK293 Cells; Host-Pathogen Interactions; Humans; Medicine, Chinese Traditional; Pandemics; Protein Binding; Resveratrol; SARS-CoV-2; Stilbenes; Surface Plasmon Resonance; Viral Proteins; Virus Replication

2021
Polydatin protects neuronal cells from hydrogen peroxide damage by activating CREB/Ngb signaling.
    Molecular medicine reports, 2022, Volume: 25, Issue:1

    Topics: Animals; Cell Death; Cyclic AMP Response Element-Binding Protein; Female; Glucosides; Hydrogen Peroxide; Male; Mice; Mice, Inbred C57BL; Mitochondria; Nerve Tissue Proteins; Neuroglobin; Neurons; Neuroprotective Agents; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Signal Transduction; Stilbenes

2022
Inhibition of Advanced Glycation End Product Formation in Rat Tail Tendons by Polydatin and p-Coumaric acid: an In Vitro Study.
    Applied biochemistry and biotechnology, 2022, Volume: 194, Issue:1

    Topics: Animals; Coumaric Acids; Glucosides; Glycation End Products, Advanced; Glycosylation; Rats; Rats, Wistar; Stilbenes; Tail; Tendons

2022
Reduction of breast tumor drug resistance by 2,3,5,4'-tetrahydroxystilbene for exhibition synergic chemotherapeutic effect.
    PloS one, 2021, Volume: 16, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Docetaxel; Doxorubicin; Drug Resistance, Neoplasm; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; Glucosides; Humans; MCF-7 Cells; Stilbenes; Zebrafish

2021
Antioxidant Activity and Mechanism of Resveratrol and Polydatin Isolated from Mulberry (
    Molecules (Basel, Switzerland), 2021, Dec-14, Volume: 26, Issue:24

    Topics: Antioxidants; Glucosides; Hep G2 Cells; Humans; Morus; Oxidative Stress; Resveratrol; Stilbenes

2021
Conductive polymer sorbent for extraction and determination of resveratrol and polydatin in Polygonum cuspidatum root samples.
    Phytochemical analysis : PCA, 2022, Volume: 33, Issue:4

    Topics: Chromatography, High Pressure Liquid; Fallopia japonica; Glucosides; Polymers; Resveratrol; Stilbenes

2022
Tetrahydroxy stilbene glycoside attenuates endothelial cell premature senescence induced by H
    Scientific reports, 2022, 02-01, Volume: 12, Issue:1

    Topics: Carbazoles; Cells, Cultured; Cellular Senescence; Gene Knockdown Techniques; Glucosides; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen Peroxide; MicroRNAs; Signal Transduction; Sirtuin 1; Stilbenes; Transfection

2022
Two new stilbene glucosides and a new benzoic acid derivative from
    Journal of Asian natural products research, 2022, Volume: 24, Issue:8

    Topics: Benzoic Acid; Boraginaceae; Glucosides; Interleukin-6; Lipopolysaccharides; Molecular Structure; Stilbenes; Tumor Necrosis Factor-alpha

2022
Polydatin combats methotrexate-induced pulmonary fibrosis in rats: Involvement of biochemical and histopathological assessment.
    Journal of biochemical and molecular toxicology, 2022, Volume: 36, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Glucosides; Glutathione; Methotrexate; Oxidative Stress; Pulmonary Fibrosis; Rats; Stilbenes

2022
Application of β-Glucosidase in a Biphasic System for the Efficient Conversion of Polydatin to Resveratrol.
    Molecules (Basel, Switzerland), 2022, Feb-23, Volume: 27, Issue:5

    Topics: Glucosides; Stilbenes

2022
2, 3, 5, 4'-tetrahydroxystilbene-2-O-beta-D-glucoside protects against neuronal cell death and traumatic brain injury-induced pathophysiology.
    Aging, 2022, 03-21, Volume: 14, Issue:6

    Topics: Animals; Apoptosis; Brain Injuries, Traumatic; Glucosides; Hippocampus; Humans; Mice; Stilbenes

2022
2,3,4',5‑Tetrahydroxystilbene‑2‑O‑β‑D‑glucoside ameliorates gentamicin‑induced ototoxicity by modulating autophagy via Sesn2/AMPK/mTOR signaling.
    International journal of molecular medicine, 2022, Volume: 49, Issue:5

    Topics: AMP-Activated Protein Kinases; Animals; Autophagy; Gentamicins; Glucosides; Mice; Ototoxicity; Stilbenes; TOR Serine-Threonine Kinases

2022
Polydatin Improves Sepsis-Associated Encephalopathy by Activating Sirt1 and Reducing p38 Phosphorylation.
    The Journal of surgical research, 2022, Volume: 276

    Topics: Adenosine Triphosphate; Animals; Cytokines; Glucosides; Mice; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Reactive Oxygen Species; Sepsis; Sepsis-Associated Encephalopathy; Sirtuin 1; Stilbenes

2022
Exploring the Parallel G-Quadruplex Nucleic Acid World: A Spectroscopic and Computational Investigation on the Binding of the c-myc Oncogene NHE III1 Region by the Phytochemical Polydatin.
    Molecules (Basel, Switzerland), 2022, May-07, Volume: 27, Issue:9

    Topics: DNA; G-Quadruplexes; Genes, myc; Glucosides; Molecular Docking Simulation; Nucleic Acids; Phytochemicals; Proto-Oncogene Proteins c-myc; Spectrum Analysis; Stilbenes

2022
Tyrosinase inhibitory mechanism and the anti-browning properties of piceid and its ester.
    Food chemistry, 2022, Oct-01, Volume: 390

    Topics: Enzyme Inhibitors; Esters; Glucosides; Kinetics; Levodopa; Molecular Docking Simulation; Monophenol Monooxygenase; Stilbenes

2022
Protective Effects of Polydatin from Grapes and
    Nutrients, 2022, May-16, Volume: 14, Issue:10

    Topics: Acetaminophen; Chemical and Drug Induced Liver Injury; Glucosides; Macrophages; Reynoutria; Stilbenes; Vitis

2022
A Systematic Strategy for the Characterization of 2,3,5,4'-Tetrahydroxystilbene-2-
    Journal of agricultural and food chemistry, 2022, Jun-29, Volume: 70, Issue:25

    Topics: Animals; Chromatography, High Pressure Liquid; Chromatography, Liquid; Glucosides; Rats; Stilbenes

2022
Polydatin attenuates chronic alcohol consumption-induced cardiomyopathy through a SIRT6-dependent mechanism.
    Food & function, 2022, Jul-04, Volume: 13, Issue:13

    Topics: Alcohol Drinking; Alcoholism; AMP-Activated Protein Kinases; Animals; Cardiomyopathy, Alcoholic; Ethanol; Glucosides; Mice; Sirtuins; Stilbenes

2022
2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucopyranoside enhances the hepatotoxicity of emodin in vitro and in vivo.
    Toxicology letters, 2022, Jul-15, Volume: 365

    Topics: Animals; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liver Injury, Chronic; Drug-Related Side Effects and Adverse Reactions; Emodin; Glucosides; Rats; Stilbenes

2022
Polydatin alleviates DSS- and TNBS-induced colitis by suppressing Th17 cell differentiation via directly inhibiting STAT3.
    Phytotherapy research : PTR, 2022, Volume: 36, Issue:9

    Topics: Animals; Cell Differentiation; Colitis; Colon; Dextran Sulfate; Disease Models, Animal; Glucosides; Inflammatory Bowel Diseases; Mice; Mice, Inbred C57BL; STAT3 Transcription Factor; Stilbenes; T-Lymphocytes, Regulatory; Th17 Cells; Trinitrobenzenesulfonic Acid

2022
Polydatin alleviates osteoporosis by enhancing the osteogenic differentiation of osteoblasts.
    European review for medical and pharmacological sciences, 2022, Volume: 26, Issue:12

    Topics: Animals; Female; Glucosides; Humans; Mice; Osteoblasts; Osteogenesis; Osteoporosis; Ovariectomy; Stilbenes

2022
Influence of Polydatin on the Tumor Microenvironment In Vitro: Studies with a Colon Cancer Cell Model.
    International journal of molecular sciences, 2022, Jul-29, Volume: 23, Issue:15

    Topics: Colonic Neoplasms; Cytokines; Endothelial Cells; Glucosides; Humans; Lipopolysaccharides; Stilbenes; Tumor Microenvironment

2022
Bioactive functional collagen-oxidized pullulan scaffold loaded with polydatin for treating chronic wounds.
    Biomaterials advances, 2022, Volume: 140

    Topics: Antioxidants; Collagen; Glucans; Glucosides; Stilbenes; Wound Healing

2022
Tetrahydroxy stilbene glucoside alters neurogenesis and neuroinflammation to ameliorate radiation-associated cognitive disability via AMPK/Tet2.
    International immunopharmacology, 2022, Volume: 110

    Topics: AMP-Activated Protein Kinases; Cognition; Dioxygenases; DNA-Binding Proteins; Glucosides; Humans; Molecular Docking Simulation; Neurogenesis; Neuroinflammatory Diseases; Stilbenes

2022
Polydatin Prevents Neuroinflammation and Relieves Depression via Regulating Sirt1/HMGB1/NF-κB Signaling in Mice.
    Neurotoxicity research, 2022, Volume: 40, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Antidepressive Agents; Antioxidants; Depression; Glucosides; HMGB1 Protein; Humans; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Neuroinflammatory Diseases; NF-kappa B; Sirtuin 1; Stilbenes; Tumor Necrosis Factor-alpha

2022
Polydatin inhibits IL-1β-mediated chondrocyte inflammation and ameliorates cartilage degradation: Involvement of the NF-κB and Wnt/β-catenin pathways.
    Tissue & cell, 2022, Volume: 78

    Topics: Aggrecans; Animals; Anti-Inflammatory Agents; beta Catenin; Cartilage, Articular; Cells, Cultured; Chondrocytes; Cyclooxygenase 2; Dinoprostone; Disintegrins; Glucosides; Inflammation; Interleukin-6; Matrix Metalloproteinase 13; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley; Stilbenes; Thrombospondins; Tumor Necrosis Factor-alpha; Wnt Signaling Pathway

2022
New stilbenes and phenolic constituents from the rhizomes of
    Journal of Asian natural products research, 2022, Volume: 24, Issue:10

    Topics: Glucosides; Iridaceae; Iris Plant; Molecular Structure; Phenols; Rhizome; Stilbenes

2022
Polydatin prevents lipotoxicity-induced dysfunction in pancreatic β-cells by inhibiting endoplasmic reticulum stress and excessive autophagy.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2022, Volume: 106

    Topics: Animals; Apoptosis; Autophagy; Cholesterol; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Endoplasmic Reticulum Stress; Fatty Acids, Nonesterified; Glucosides; Insulin Resistance; Insulin-Secreting Cells; Mice; Palmitates; Stilbenes; Tunicamycin

2022
Polydatin reverses oxidation low lipoprotein (oxLDL)-induced apoptosis of human umbilical vein endothelial cells via regulating the miR-26a-5p/BID axis.
    European journal of histochemistry : EJH, 2022, Sep-20, Volume: 66, Issue:4

    Topics: Apoptosis; Atherosclerosis; Glucosides; Human Umbilical Vein Endothelial Cells; Humans; Lipoproteins, LDL; MicroRNAs; Stilbenes

2022
In Vitro and in Silico Investigation of DNA Interaction, Topoisomerase I and II Inhibitory Properties of Polydatin.
    Chemistry & biodiversity, 2022, Volume: 19, Issue:10

    Topics: DNA; DNA Topoisomerases, Type II; Glucosides; Molecular Docking Simulation; Resveratrol; Stilbenes

2022
Polydatin Attenuates Cisplatin-Induced Acute Kidney Injury via SIRT6-Mediated Autophagy Activation.
    Oxidative medicine and cellular longevity, 2022, Volume: 2022

    Topics: Acute Kidney Injury; Animals; Apoptosis; Autophagy; Chloroquine; Cisplatin; Glucosides; Glutathione; Interleukin-1beta; Kidney; Malondialdehyde; Mice; Microtubule-Associated Proteins; Peroxidase; Sirtuins; Stilbenes; Superoxide Dismutase; Tumor Necrosis Factor-alpha

2022
Is It Possible to Improve the Bioavailability of Resveratrol and Polydatin Derived from
    Nutrients, 2022, Sep-21, Volume: 14, Issue:19

    Topics: Antioxidants; Biological Availability; Cyclodextrins; Drugs, Chinese Herbal; Glucosides; Methanol; Nanofibers; Povidone; Resveratrol; Stilbenes

2022
2,3,5,4'-Tetrahydroxy stilbene-2-Ο-β-D-glucoside, a mechanism-based inactivator of CYP2C19 and CYP3A4, potentiates hepatic protein adduction and hepatotoxicity induced by emodin in vivo.
    Chemico-biological interactions, 2022, Dec-01, Volume: 368

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Emodin; Glucosides; Humans; Mice; Stilbenes

2022
Astringin protects LPS-induced toxicity by suppressing oxidative stress and inflammation via suppression of PI3K/AKT/NF-κB pathway for pediatric acute lung injury.
    Naunyn-Schmiedeberg's archives of pharmacology, 2023, Volume: 396, Issue:10

    Topics: Acute Lung Injury; Child; Glucosides; Humans; Inflammation; Lipopolysaccharides; Lung; NF-kappa B; Oxidative Stress; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; Stilbenes

2023
Protective effects of polydatin on ileum injury in mice exposed to aflatoxin B1.
    Toxicon : official journal of the International Society on Toxinology, 2023, Aug-15, Volume: 232

    Topics: Aflatoxin B1; Animals; Body Weight; Glucosides; Humans; Ileum; Inflammation; Liver; Male; Mice; Oxidative Stress; RNA, Messenger; Stilbenes

2023
Exosome-coated polydatin nanoparticles in the treatment of radiation-induced intestinal damage.
    Aging, 2023, 07-18, Volume: 15, Issue:14

    Topics: Animals; Exosomes; Glucosides; Humans; Mice; Phosphatidylinositol 3-Kinases; Stilbenes

2023