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glucose, (beta-d)-isomer and sergliflozin etabonate

glucose, (beta-d)-isomer has been researched along with sergliflozin etabonate in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (50.00)29.6817
2010's5 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fujikura, H; Fujimori, Y; Hiratochi, M; Isaji, M; Itoh, F; Katsuno, K; Komatsu, Y; Takemura, Y1
Isaji, M1
Goldstein, BJ; Jabbour, SA1
Fujimori, Y; Isaji, M; Ishikawa-Takemura, Y; Katsuno, K; Kusama, H; Nakano, S; Nakashima, I; Ojima, K1
Fujimori, Y; Isaji, M; Ishikawa-Takemura, Y; Katsuno, K1
Amin, DM; Clark, RV; Dobbins, RL; Hussey, EK; Kipnes, MS; Layko, D; Leong, J; Murray, SC; Nunez, DJ; O'Connor-Semmes, RL; O'Driscoll, EC1
Dobbins, RL; Hussey, EK; Kapur, A; Layko, D; Murray, SC; Nunez, DJ; O'Connor-Semmes, RL; Stockman, NL; Stoltz, RR1
Sharma, K; Vallon, V1
Chan, JY; Lau, CB; Ng, WL; Shing, TK1
Babu, RJ; Dash, RP; Srinivas, NR1

Reviews

4 review(s) available for glucose, (beta-d)-isomer and sergliflozin etabonate

ArticleYear
Sodium-glucose cotransporter inhibitors for diabetes.
    Current opinion in investigational drugs (London, England : 2000), 2007, Volume: 8, Issue:4

    Topics: Animals; Carbonates; Clinical Trials, Phase II as Topic; Diabetes Mellitus, Type 2; Glucosides; Humans; Hypoglycemic Agents; Molecular Structure; Sodium-Glucose Transport Proteins

2007
Sodium glucose co-transporter 2 inhibitors: blocking renal tubular reabsorption of glucose to improve glycaemic control in patients with diabetes.
    International journal of clinical practice, 2008, Volume: 62, Issue:8

    Topics: Adolescent; Adult; Aged; Benzhydryl Compounds; Blood Glucose; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Female; Glucosides; Humans; Hypoglycemic Agents; Male; Middle Aged; Sodium-Glucose Transporter 2 Inhibitors

2008
Sodium-glucose transport: role in diabetes mellitus and potential clinical implications.
    Current opinion in nephrology and hypertension, 2010, Volume: 19, Issue:5

    Topics: Absorption; Benzhydryl Compounds; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Glucose; Glucosides; Humans; Kidney; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors

2010
Comparative pharmacokinetics of three SGLT-2 inhibitors sergliflozin, remogliflozin and ertugliflozin: an overview.
    Xenobiotica; the fate of foreign compounds in biological systems, 2017, Volume: 47, Issue:11

    Topics: Blood Glucose; Bridged Bicyclo Compounds, Heterocyclic; Diabetes Mellitus, Type 2; Glucosides; Half-Life; Humans; Hypoglycemic Agents; Pyrazoles; Sodium-Glucose Transporter 2

2017

Trials

2 trial(s) available for glucose, (beta-d)-isomer and sergliflozin etabonate

ArticleYear
Single-dose pharmacokinetics and pharmacodynamics of sergliflozin etabonate, a novel inhibitor of glucose reabsorption, in healthy volunteers and patients with type 2 diabetes mellitus.
    Journal of clinical pharmacology, 2010, Volume: 50, Issue:6

    Topics: Administration, Oral; Adolescent; Adult; Area Under Curve; Benzhydryl Compounds; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Monitoring; Female; Glucose; Glucosides; Glycosuria; Humans; Hypoglycemic Agents; Male; Middle Aged; Prodrugs; Water-Electrolyte Balance

2010
Multiple-dose pharmacokinetics and pharmacodynamics of sergliflozin etabonate, a novel inhibitor of glucose reabsorption, in healthy overweight and obese subjects: a randomized double-blind study.
    Journal of clinical pharmacology, 2010, Volume: 50, Issue:6

    Topics: Adolescent; Adult; Benzhydryl Compounds; Blood Glucose; Body Weight; Dose-Response Relationship, Drug; Drug Monitoring; Female; Glucosides; Glycosuria; Half-Life; Humans; Insulin; Male; Middle Aged; Obesity; Overweight; Prodrugs; Water-Electrolyte Balance

2010

Other Studies

4 other study(ies) available for glucose, (beta-d)-isomer and sergliflozin etabonate

ArticleYear
Sergliflozin, a novel selective inhibitor of low-affinity sodium glucose cotransporter (SGLT2), validates the critical role of SGLT2 in renal glucose reabsorption and modulates plasma glucose level.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 320, Issue:1

    Topics: Absorption; Animals; Blood Glucose; Dogs; Electrolytes; Erythrocytes; Female; Glucose; Glucose Tolerance Test; Glucosides; Glycosuria; Hypoglycemic Agents; Kidney; Male; Mice; Mice, Inbred C57BL; Rats; Rats, Sprague-Dawley; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors

2007
Sergliflozin etabonate, a selective SGLT2 inhibitor, improves glycemic control in streptozotocin-induced diabetic rats and Zucker fatty rats.
    European journal of pharmacology, 2009, May-01, Volume: 609, Issue:1-3

    Topics: Animals; Area Under Curve; Blood Glucose; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Fasting; Glucose Tolerance Test; Glucosides; Glycated Hemoglobin; Glycosuria; Hypoglycemic Agents; Insulin; Kinetics; Male; Rats; Rats, Zucker; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Streptozocin

2009
Long-term treatment with sergliflozin etabonate improves disturbed glucose metabolism in KK-A(y) mice.
    European journal of pharmacology, 2009, Sep-15, Volume: 618, Issue:1-3

    Topics: Administration, Oral; Animals; Benzhydryl Compounds; Drug Administration Schedule; Female; Glucose; Glucosides; Hyperinsulinism; Hypoglycemic Agents; Mice; Mice, Inbred Strains; Obesity; Time Factors

2009
Design, syntheses, and SAR studies of carbocyclic analogues of sergliflozin as potent sodium-dependent glucose cotransporter 2 inhibitors.
    Angewandte Chemie (International ed. in English), 2013, Aug-05, Volume: 52, Issue:32

    Topics: Glucosides; Humans; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Structure-Activity Relationship

2013