glucose, (beta-d)-isomer has been researched along with leukotriene b4 in 183 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 66 (36.07) | 18.7374 |
| 1990's | 71 (38.80) | 18.2507 |
| 2000's | 25 (13.66) | 29.6817 |
| 2010's | 15 (8.20) | 24.3611 |
| 2020's | 6 (3.28) | 2.80 |
| Authors | Studies |
|---|---|
| Petersen, MM; Steadman, R; Williams, JD | 3 |
| Barnes, PJ; Chung, KF; Dent, G; Perkins, RS | 1 |
| Bach, MK; Brashler, JR; Petzold, EN; Sanders, ME | 1 |
| Donigi-Gale, D; Edwards, R; Norman, KE; Rossi, AG; Shoupe, TS; Williams, TJ | 1 |
| Askaa, J; Bjerrum, OW; Borregaard, N; Kjeldsen, L | 1 |
| Abe, M; Goya, T; Muranishi, H; Nagata, N; Shigematsu, N; Takahashi, H | 1 |
| Heidel, JR; Laegreid, WW; Leid, RW; Silflow, RM; Taylor, SM | 1 |
| Faccioli, LH; Kay, AB; Moqbel, R; Nourshargh, S; Sehmi, R; Williams, FM; Williams, TJ | 1 |
| Letari, O; Malgaroli, A; Morgan, DW; Nicosia, S; Welton, AF | 1 |
| Ferrándiz, ML; Foster, SJ | 1 |
| Blackham, A; Griffiths, RJ; Li, SW; Wood, BE | 1 |
| König, W; Raulf, M | 2 |
| Beavis, MJ; Coles, GA; Davies, M; Faict, D; Mackenzie, R; Peluso, F; Petersen, MM; Thomas, N; Topley, N; Williams, D | 1 |
| Balazovich, K; McNish, RW; Peters-Golden, M; Sporn, PH | 1 |
| Flower, RJ; Peers, SH | 1 |
| Elstad, MR; McIntyre, TM; Prescott, SM; Zimmerman, GA | 1 |
| Goldman, G; Hechtman, HB; Klausner, JM; Kobzik, L; Shepro, D; Valeri, CR; Welbourn, R | 1 |
| Crivellari, MT; De Rose, V; Folco, GC; Gialdroni Grassi, G; Masciarelli, M; Pozzi, E; Semenzato, G; Trentin, L; Viganò, T | 1 |
| Chi, EY; Forstrom, JW; Goodman, RB; Martin, TR; Osborn, SG | 1 |
| Habermehl, GG; Meier, B; Radeke, HH; Resch, K; Selle, S; Sies, H | 1 |
| Bloomfield, FJ; Hogan, FP; Keating, JJ; Keeling, PW; Kelleher, D; MacDonald, GS; Maxwell, WJ | 1 |
| Nourshargh, S; Williams, TJ | 1 |
| Granger, DN; Grisham, MB; Zimmerman, BJ | 1 |
| Fish, JE; Flynn, JT; Peters, SP; Spannhake, EW; Yoss, EB | 1 |
| Matthews, N; Petersen, MM; Spur, B; Steadman, R; Topley, N; Williams, D; Williams, JD | 1 |
| Allington, LA; Gossman, GL; Kendall, TJ; Rennard, SI; Robbins, RA; Stull, TW | 1 |
| Hallett, MB; Matthews, N; Petersen, M; Steadman, R; Williams, JD | 1 |
| Bruijnzeel, PL; Kok, PT; Kreukniet, J; Warringa, RA | 1 |
| Banks, KL; Englen, MD; Laegreid, WW; Silflow, RM; Taylor, SM; Wes Leid, R | 1 |
| Alouf, JE; König, W; Raulf, M | 1 |
| Brown, TT; Fleisher, LN; MacLachlan, NJ; O'Sullivan, MG; Olson, NC | 1 |
| Leonard, EJ; Rankin, JA; Smith, S; Sylvester, I; Yoshimura, T | 1 |
| Eyre, P; McEwen, BJ; Wilcock, BP | 1 |
| Bacon, KB; Camp, RD; Ross, JS | 1 |
| Goebel, W; Hacker, J; König, W; Scheffer, J | 1 |
| Aussel, C; Fehlmann, M | 1 |
| Balter, MS; Peters-Golden, M; Toews, GB | 1 |
| Danner, RL; Doerfler, ME; Parrillo, JE; Shelhamer, JH | 1 |
| Brom, J; Erbs, G; Köller, M; König, W; Müller, FE | 1 |
| Bruijnzeel, PL; Hamelink, ML; Kok, PT; Kreukniet, J | 1 |
| Chavis, C; Crastes de Paulet, A; Damon, M; Daures, JP; Godard, P; Michel, FB | 1 |
| Burgess, JR; Eskew, ML; Hildenbrandt, G; Reddy, CC; Scheuchenzuber, WJ; Scholz, RW; Zarkower, A | 1 |
| Brunden, MN; Czuk, CI; Morris, J; Sun, FF; Taylor, BM; Wishka, DG | 1 |
| Bruijnzeel, PL; Hamelink, ML; Kok, PT; Kreukniet, J; Warringa, RA | 1 |
| Alouf, JE; Hensler, T; König, W; Megret, F; Raulf, M | 1 |
| Kobayashi, K; Mizoguchi, Y; Morisawa, S; Sakagami, Y; Seki, S; Yamamoto, S | 1 |
| Borgeat, P; Bourgoin, S; Naccache, PH; Poubelle, PE | 1 |
| Adamchak, MA; Boctor, AM; Flynn, DL; Jordan, JH; Kostlan, CR; Lesch, ME; Okonkwo, GC; Schrier, DJ | 1 |
| Fradin, A; Henson, PM; Maclouf, J; Murphy, RC; Vausbinder, L; Zirrolli, JA | 1 |
| Edenius, C; Lindgren, JA; Sjöquist, B; Smedegård, G; Tornhamre, S | 1 |
| Henderson, WR; Martin, TR; Merritt, TL; Raugi, G | 1 |
| Care, SB; Merrill, WW; Naegel, GP; Reynolds, HY; Sibille, Y; Young, KR | 1 |
| Giedd, KN; Haines, KA; Korchak, HM; Reibman, J; Rich, AM; Weissmann, G | 1 |
| Coffey, JW; Fiedler-Nagy, C; Georgiadis, A; Hope, WC; Welton, AF; Wittreich, BH | 1 |
| German, JB; Kinsella, JE; Lokesh, B | 1 |
| Claesson, HE; Lindgren, JA; Odlander, B | 1 |
| Moser, U; Roth, HJ; Schmidt, KH; Steinhilber, D | 1 |
| Gonzalez-Crussi, F; Henderson, S; Hsueh, W | 1 |
| Borish, L; Rocklin, RE; Schainberg, H | 1 |
| Peters-Golden, M; Sporn, PH | 1 |
| Austen, KF; Czop, JK; Miorandi, DZ; Puglisi, AV | 1 |
| Calvano, S; Dineen, P; Duhaney, R; Fong, Y; Hesse, DG; Meyer, J; Richardson, D; Shires, GT; Tracey, KJ; Yurt, RW | 1 |
| Dineen, P; Duhaney, R; Fong, YM; Hesse, DG; Lowry, SF; Meyer, JD; Shires, GT; Tracey, KJ; Verma, M; Yurt, RW | 1 |
| Bar-Shavit, Z; Stenson, WF; Teitelbaum, SL | 1 |
| Arm, JP; Clark, TJ; Horton, CE; House, F; Lee, TH; Spur, BW | 1 |
| Berkenkopf, JW; Weichman, BM | 1 |
| Austen, F; Lee, TH; Lewis, RA; Williams, JD | 1 |
| Griffin, GL; Kreisle, RA; Parker, CW; Senior, RM; Stenson, WF | 1 |
| Austen, KF; Czop, JK | 1 |
| Moncada, S; Salmon, JA; Tilling, LC | 1 |
| Lindgren, JA; Palmblad, J; Ringertz, B | 1 |
| Bruynzeel, PL; Hamelink, ML; Kijne, AM; Kok, PT; Verhagen, J | 1 |
| Bonney, RJ; Humes, JL; Opas, EE | 1 |
| Gairola, C; Tai, HH | 1 |
| Lewis, RA | 1 |
| Beaver, TH; Borgeat, P; Doherty, NS; Poubelle, P; Schrader, NL; Westrich, GL | 1 |
| Arnout, J; Coene, MC; Deckmyn, H; Gresele, P; Vermylen, J | 1 |
| Adams, DO; Lewis, JG | 1 |
| Barker, C; Biggar, WD; Bohn, D; Crawford, L; Hamilton, G; Kent, G | 1 |
| Roth, JA; Webb, DS | 1 |
| McIver, DJ; Paterson, NA; Schurch, S | 1 |
| Giedd, KN; Haines, KA; Korchak, HM; Rich, AM; Weissmann, G | 1 |
| Mandell, BF | 1 |
| Peters-Golden, M; Thebert, P | 1 |
| Chambers, JD; Evans, AM; Hobbs, JR | 1 |
| Ishida, E; Ito, M; Kawade, Y; Shigeta, S; Tanabe, F; Watanabe, Y | 1 |
| Augustine, NH; Hill, HR; McFall, TL; Zimmerman, GA | 1 |
| Colditz, IG; Movat, HZ | 1 |
| Brunet, G; Charleson, S; Ford-Hutchinson, AW; Savard, P | 1 |
| Cole, PJ; Dollery, CT; Fuller, RW; Kelsey, CR; MacDermot, J | 1 |
| Claesson, HE; Lundberg, U; Malmsten, C | 1 |
| Hsueh, W; Sun, FF | 1 |
| Chang, J; Liu, MC; Newcombe, DS | 1 |
| Flynn, JT; Gee, MH; Havill, AM; Perkowski, SZ | 1 |
| Palmer, RM; Salmon, JA | 1 |
| Czarnetzki, BM; Pawelzik, B | 1 |
| Bonney, RJ; Humes, JL | 1 |
| Burrowes, CE; Johnston, MG; Movat, HZ; Rettl, C | 1 |
| Austen, KF; Czop, JK; Williams, JD | 1 |
| Kus, M; Tanda, K; Williams, FM; Williams, TJ | 1 |
| Clark, JD; Doerfler, ME; Elsbach, P; Weiss, J | 1 |
| Ferin, MA; Kennedy, JA; Kuipers, PJ; Wright, CD | 1 |
| Leduc, D; Pretolani, M; Vargaftig, BB; Zuany-Amorim, C | 1 |
| Kato, M; Miyamoto, M; Sugawara, T; Takayama, S | 1 |
| Nourshargh, S; Sanz, MJ; Walsh, DT; Weg, VB; Williams, TJ | 1 |
| Caniglia, M; Ciccimarra, F; Palumbo, A; Romano, G; Santoro, P; Viggiano, D | 1 |
| Currie, JL; Isakson, PC; Rao, TS; Shaffer, AF | 1 |
| Kristjansson, S; Shimizu, T; Strandvik, B; Strannegård, IL; Wennergren, G | 2 |
| Hansson, GC; Shimizu, T; Strandvik, B | 1 |
| Borgeat, P; Marleau, S; Odeimat, A; Palmantier, R; Poubelle, PE; Surette, ME | 1 |
| Fruchtmann, R; Fugmann, B; Hatzelmann, A; Horstmann, H; Junge, B; Mohrs, KH; Müller-Peddinghaus, R; Raddatz, S | 1 |
| Coles, GA; Gahl, GM; Jörres, A; Liberek, T; Petersen, MM; Topley, N; Williams, JD | 1 |
| Goracci, G; Gresele, P; Mezzasoma, AM; Nenci, GG; Prosdocimi, M; Quero, E; Ribaldi, E; Stasi, M | 1 |
| Lobb, RR; Nourshargh, S; Weg, VB; Williams, TJ | 1 |
| Cassuto, J; Eriksson, AS; Gretzer, C; Sinclair, R; Thomsen, P | 1 |
| Vardey, CJ; Wheeldon, A | 1 |
| Brain, S; Nourshargh, S; Williams, TJ; Yarwood, H | 1 |
| Azzari, C; Baldi, E; Carloni, V; Gentilini, P; Gresele, P; Laffi, G; Marra, F; Rossi, ME | 1 |
| Tool, AT; Verhoeven, AJ | 1 |
| Medvedeff, ED; Nickerson-Nutter, CL | 1 |
| Alcaraz, MJ; Ferrándiz, ML; Payá, M; Terencio, MC | 1 |
| Fóris, G; Leövey, A; Mezösi, E; Nagy, EV; Paragh, G; Szabó, J; Sztojka, I | 1 |
| Hellewell, PG; Macari, DM; Teixeira, MM | 1 |
| Kikuchi, M; Naito, K; Tsuzurahara, K | 1 |
| Alcaraz, MJ; Erazo, S; Ferrándiz, ML; Gil, B; González, E; Negrete, R; Pacheco, S; Payá, M; Sanz, MJ; Ubeda, A | 1 |
| Murphy, RC; Wheelan, P | 1 |
| Cipriani, A; Crivellari, MT; De Rose, V; Folco, G; Gialdroni Grassi, G; Pozzi, E; Semenzato, G; Trentin, L | 1 |
| Carty, TJ; Cheng, JD; Ernest, MJ; Eskra, JD; Griffiths, RJ; Joseph, PA; Kadin, SB; Loose, LD; Moore, PF; Murase, S; Nagahisa, A; Pazoles, PP; Pillar, JS; Sweeney, FJ | 1 |
| Dalsgaard, CJ; Haegerstrand, A; Martinsson, T | 1 |
| Braam, U; Brosthardt, P; Schmutzler, W; Servais, MD; Zwadlo-Klarwasser, G | 1 |
| Alpert, R; Conklyn, MJ; Cortina, SR; Griffiths, RJ; Hingorani, GP; Koch, K; Lopez-Anaya, A; Meltzer, S; Milici, AJ; Pettipher, ER; Piscopio, AD; Reiter, LA; Salter, ED; Scampoli, DN; Showell, HJ; Smith, MA; Stam, E; Wright, KF | 1 |
| Fiedler, J; Henson, PM; Murphy, RC; Wheelan, P | 1 |
| Shahan, TA; Simpson, J; Sorenson, WG | 1 |
| Alcaraz, MJ; González, LM; Guillén, I; Peinador, C; Quintela, JM; Riguera, R; Rioja, I; Terencio, MC; Ubeda, A | 1 |
| Alcaraz, MJ; Guillén, MI; Vicente, AM | 1 |
| Ikeshiro, Y; Kashiwada, Y; Miwa, Y; Taga, T; Takanaka, K; Tanaka, S; Tsukada, H | 1 |
| Blodgett, JL; Bloodworth, RC; McManus, LM; Pinckard, RN; Prihoda, TJ | 1 |
| Acero-Alarcon, A; Alcaraz, MJ; Ferrándiz, ML; Sepulveda-Arques, J; Ubeda, A; Vidal, A | 1 |
| Borgeat, P; Flamand, L; Gosselin, J; Savard, M; Tardif, M | 1 |
| Giner, RM; Góngora, L; Máñez, S; Recio, Mdel C; Ríos, JL; Schinella, G | 1 |
| Lim, BO | 1 |
| Giner, RM; Máñez, S; Recio, MC; Ríos, JL; Sala, A; Schinella, GR | 1 |
| Arita, M; Bannenberg, G; Devchand, PR; Gronert, K; Hong, S; Moussignac, RL; Serhan, CN | 1 |
| Alves, M; del Olmo, E; Lucas, R; Payá, M; San Feliciano, A | 1 |
| Bacon, KB; Gantner, F; Sakai, K; Takeshita, K | 1 |
| Alcaraz, MJ; Guillén, MI; Habib, A; Vicente, AM | 1 |
| Bezerra, MM; Cunha, Fde Q; da Rocha, FA; Girão, VC; Ribeiro, Rde A; Rocha, JC; Teixeira, MM | 1 |
| Biedroń, R; Bobek, M; Jozefowski, S; Marcinkiewicz, J | 1 |
| Bloomfield, FJ; Breathnach, R; Donahy, C; Jones, BR | 1 |
| Batzer, J; Ceilley, RI; Immeyer, J; Kolbe, L; Mundt, C; Schönrock, U; Stäb, F; tom Dieck, K; Wenck, H; Wensorra, U; Wolber, R | 1 |
| Bezerra, MM; Carvalho, AP; Cunha, FQ; Girão, VC; Rocha, FA | 1 |
| Bas, E; Escandell, JM; Giner, RM; López-Ginés, C; Máñez, S; Recio, MC; Ríos, JL | 1 |
| Kubes, P; Mullaly, SC | 1 |
| Castañeda-Hernández, G; Chávez-Piña, AE; Dicay, M; McKnight, W; Wallace, JL | 1 |
| Canetti, C; Cunha, FQ; Cunha, TM; Dal-Secco, D; Ferreira, SH; Guerrero, AT; Parada, CA; Rocha, FA; Schivo, IR; Silva, TA; Verri, WA | 1 |
| Barja-Fidalgo, C; Conte, Fde P; Cunha, FQ; Henriques, Md; Penido, C; Rae, GA; Verri, WA | 1 |
| Cunha, FQ; Dal-Secco, D; Fukada, SY; Girão, VC; Leite, AC; Rocha, FA | 1 |
| Arruda, JM; Baccei, C; Bain, G; Broadhead, AR; Chapman, C; Correa, LD; Darlington, JV; Evans, JF; Hutchinson, JH; King, C; Lee, C; Li, Y; Lorrain, DS; Prodanovich, P; Santini, AM | 1 |
| Baccei, CS; Bain, G; Broadhead, AR; Chapman, C; Correa, LD; Darlington, JV; Evans, JF; Hutchinson, JH; King, CD; Lee, C; Lorrain, DS; Prasit, P; Prodanovich, PP; Roppe, J; Santini, AM; Stearns, B; Stock, NS; Zunic, J | 1 |
| Hung, ND; Kim, MR; Sok, DE | 1 |
| Kwon, HJ; Park, MY; Sung, MK | 1 |
| Bani, S; Gupta, BD; Pandey, A; Satti, NK; Suri, KA | 1 |
| Chiang, N; Dalli, J; Fredman, G; Li, Y; Serhan, CN | 1 |
| Davis, JM; Parks, KR | 1 |
| Cunha, FQ; Cunha, TM; Ferreira, SH; Guerrero, AT; Pinto, LG; Verri, WA; Vieira, SM; Zaperlon, AC; Zarpelon, AC | 1 |
| Buret, AG; Duquette, SC; Feener, TD; Fischer, CD; Hollenberg, MD; Lucas, MJ; Morck, DW; Renaux, BS | 1 |
| Pace, S; Pergola, C; Rådmark, O; Rossi, A; Sautebin, L; Werz, O | 1 |
| Barreda, DR; Buret, AG; Duquette, SC; Feener, TD; Fischer, CD; Morck, DW; Muench, GP; Nickerson, JG | 1 |
| Allison, J; Bhargava, A; Buret, AG; Duquette, SC; Feener, TD; Fischer, CD; Lucas, MJ; Morck, DW; Muench, GP; Reti, KL; Sajedy, S; Williams, AC | 1 |
| Chang, X; Gao, J; Gong, S; He, H; Jiang, W; Luo, F; Wei, T; Yan, T; Zhu, L | 1 |
| Alcaraz, MJ; Carceller, MC; Ferrándiz, ML; Guillén, MI | 1 |
| Barreda, DR; Havixbeck, JJ; Hodgkinson, JW; Rieger, AM; Wong, ME | 1 |
| Capasso, R; Guerra, G; Izzo, AA; Pace, S; Pagano, E; Rossi, A; Roviezzo, F; Tedesco, F; Troisi, F; Werner, M; Werz, O; Zjawiony, JK | 1 |
| Bosso, MA; Ezeamuzie, CI; Phillips, OA | 1 |
| Arai, H; Hayashi, S; Hishida, A; Kawahara, N; Kirikoshi, J; Mizukami, M; Sato, D; Takasugi, M; Wu, M; Yamagishi, T; Yang, L | 1 |
| Auger, JL; Binstadt, B; Brouwers, H; Clària, J; Freysdottir, J; Garrido-Mesa, J; Giera, M; Gonzalez-Torres, M; Hardardottir, I; Huizinga, TWJ; Ioan-Facsinay, A; Jónasdóttir, HS; Kloppenburg, M; Kuipers, ME; Kwekkeboom, JC; López-Vicario, C; Norling, LV; Perretti, M; Toes, REM | 1 |
| Berretta, M; Bonelli, A; Botti, G; Caronna, A; Cocco, S; Conforti, G; De Laurentiis, M; Lombari, MC; Maurea, N; Quagliariello, V; Rea, G | 1 |
| Bachellier-Bassi, S; Bousso, P; Corre, B; d'Enfert, C; Garcia, Z; Khazen, R; Lemaître, F | 1 |
| Bagaitkar, J; Bhattacharya, S; Dinauer, MC; Greenberg, ZJ; Huang, G; Schuettpelz, LG; Song, Z; Yang, W | 1 |
2 review(s) available for glucose, (beta-d)-isomer and leukotriene b4
| Article | Year |
|---|---|
Lipoxygenase pathways of macrophages.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Leukotrienes; Lipid Peroxides; Lipoxygenase; Lymphocyte Activation; Macrophages; Mice; Prostaglandin-Endoperoxide Synthases; Rats; SRS-A; T-Lymphocytes; Zymosan | 1985 |
Epinephrine, cortisol, endotoxin, nutrition, and the neutrophil.
Topics: Animals; Endotoxins; Epinephrine; Humans; Hydrocortisone; Immunity, Humoral; Inflammation; Leukotriene B4; Models, Biological; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nutritional Support; Zymosan | 2012 |
3 trial(s) available for glucose, (beta-d)-isomer and leukotriene b4
| Article | Year |
|---|---|
Arachidonic acid metabolism in normal human alveolar macrophages: stimulus specificity for mediator release and phospholipid metabolism, and pharmacologic modulation in vitro and in vivo.
Topics: Arachidonic Acids; Calcimycin; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cyclooxygenase Inhibitors; Dexamethasone; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Macrophage Activation; Macrophages; Phosphatidylcholines; Phosphatidylinositols; Pulmonary Alveoli; Radioimmunoassay; Tetradecanoylphorbol Acetate; Thromboxane B2; Zymosan | 1990 |
Anti-inflammatory efficacy of Licochalcone A: correlation of clinical potency and in vitro effects.
Topics: Administration, Topical; Adult; Anti-Inflammatory Agents; Cells, Cultured; Chalcones; Dinoprostone; Erythema; Granulocytes; Humans; Interleukin-6; Keratinocytes; Leukotriene B4; Middle Aged; Plant Extracts; Prospective Studies; Respiratory Burst; Tumor Necrosis Factor-alpha; Ultraviolet Rays; Zymosan | 2006 |
Anti-inflammatory effects of retinoids and carotenoid derivatives on caspase-3-dependent apoptosis and efferocytosis of bovine neutrophils.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Bronchoalveolar Lavage Fluid; Carotenoids; Caspase 3; Cattle; Female; Leukocytes; Leukotriene B4; Macrophages; Male; Mannheimia haemolytica; Neutrophils; Pasteurellaceae Infections; Phagocytosis; Retinoids; Zymosan | 2014 |
178 other study(ies) available for glucose, (beta-d)-isomer and leukotriene b4
| Article | Year |
|---|---|
Protein kinase C activation modulates tumour necrosis factor-alpha priming of human neutrophils for zymosan-induced leukotriene B4 release.
Topics: Alkaloids; Dose-Response Relationship, Immunologic; Humans; Leukotriene B4; Macrophage-1 Antigen; Neutrophils; Protein Kinase C; Recombinant Proteins; Staurosporine; Tumor Necrosis Factor-alpha; Zymosan | 1992 |
The effect of anion transport inhibitors and extracellular Cl- concentration on eosinophil respiratory burst activity.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Biological Transport; Chlorides; Dose-Response Relationship, Drug; Eosinophils; Furosemide; Guinea Pigs; Hydrogen Peroxide; Leukotriene B4; Nitrobenzoates; Respiratory Burst; Zymosan | 1992 |
Superoxide production by human eosinophils can be inhibited in an agonist-selective manner.
Topics: Alkaloids; Androstadienes; Carbazoles; Eosinophils; Humans; Immunoglobulin G; Indole Alkaloids; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Protein Kinase C; Sphingosine; Staurosporine; Superoxides; Tetradecanoylphorbol Acetate; Wortmannin; Zymosan | 1992 |
The role of complement, platelet-activating factor and leukotriene B4 in a reversed passive Arthus reaction.
Topics: Animals; Arthus Reaction; Azepines; Complement System Proteins; Edema; Isoquinolines; Leukotriene B4; Platelet Activating Factor; Rabbits; Radioimmunoassay; Receptors, Complement; Tetrazoles; Triazoles; Zymosan | 1992 |
Subcellular localization and release of human neutrophil gelatinase, confirming the existence of separate gelatinase-containing granules.
Topics: Cytoplasmic Granules; Enzyme-Linked Immunosorbent Assay; Gelatinases; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Lactoferrin; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Pepsin A; Platelet Activating Factor; Protein Binding; Subcellular Fractions; Vitamin B 12; Zymosan | 1992 |
Time-dependent alterations of leukotriene production and catabolism in rat peritoneal macrophages following intraperitoneal injection of thioglycollate broth.
Topics: Animals; Arachidonic Acid; Calcimycin; Cell Count; gamma-Glutamyltransferase; Leukotriene B4; Macrophage Activation; Macrophages; Male; Membrane Lipids; Peritonitis; Rats; Rats, Inbred Strains; SRS-A; Thioglycolates; Time Factors; Zymosan | 1992 |
Characterization of arachidonic acid metabolism, superoxide production, and bacterial killing by bovine alveolar neutrophils elicited with leukotriene B4 and zymosan-activated plasma.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Bacteriolysis; Calcimycin; Cattle; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Male; Neutrophils; Pulmonary Alveoli; Superoxides; Zymosan | 1991 |
The accumulation of 111In-eosinophils induced by inflammatory mediators, in vivo.
Topics: Albumins; Animals; Cell Movement; Complement C5a; Dermatitis, Atopic; Eosinophils; Female; Guinea Pigs; Indium Radioisotopes; Leukotriene B4; Platelet Activating Factor; Recombinant Proteins; Skin; Zymosan | 1991 |
Cytosolic calcium ion and arachidonic acid release and metabolism in macrophages.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium; Cytosol; Eicosanoic Acids; Epoprostenol; Fura-2; In Vitro Techniques; L-Lactate Dehydrogenase; Leukotriene B4; Lipopolysaccharides; Macrophages; Male; Microchemistry; Phagocytosis; Phospholipases A; Rats; Rats, Inbred Strains; Spectrometry, Fluorescence; Zymosan | 1991 |
Tumour necrosis factor production in a rat airpouch model of inflammation: role of eicosanoids.
Topics: Animals; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Indomethacin; Inflammation; Kinetics; Leukotriene B4; Lipopolysaccharides; Lipoxygenase Inhibitors; Male; Rats; Rats, Inbred Strains; SRS-A; Tumor Necrosis Factor-alpha; Zymosan | 1991 |
A comparison of the anti-inflammatory activity of selective 5-lipoxygenase inhibitors with dexamethasone and colchicine in a model of zymosan induced inflammation in the rat knee joint and peritoneal cavity.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arthritis; Benzeneacetamides; Calcimycin; Colchicine; Dexamethasone; Dinoprostone; Disease Models, Animal; Hydroxamic Acids; Inflammation; Kinetics; Knee Joint; Leukocytes; Leukotriene B4; Leukotrienes; Lipoxygenase Inhibitors; Male; Peritonitis; Pyrazoles; Rats; Zymosan | 1991 |
Modulation of leukotriene generation from human polymorphonuclear granulocytes by polychlorinated biphenyls (PCB).
Topics: Calcimycin; Cells, Cultured; Humans; In Vitro Techniques; Leukotriene B4; Luminescent Measurements; Neutrophils; Polychlorinated Biphenyls; Sodium Fluoride; Zymosan | 1991 |
In vitro testing of a potentially biocompatible continuous ambulatory peritoneal dialysis fluid.
Topics: Bacteria; Cell Count; Cell Survival; Dialysis Solutions; Epithelial Cells; Epithelium; Humans; Leukotriene B4; Luminescent Measurements; Neutrophils; Peritoneal Dialysis, Continuous Ambulatory; Phagocytosis; Zymosan | 1991 |
Basal activation of protein kinase C in rat alveolar macrophages: implications for arachidonate metabolism.
Topics: Alkaloids; Animals; Arachidonic Acids; Basal Metabolism; Calcimycin; Cells, Cultured; Enzyme Activation; Female; Leukotriene B4; Macrophages, Alveolar; Peritoneum; Protein Kinase C; Rats; Rats, Inbred Strains; Staurosporine; Tetradecanoylphorbol Acetate; Zymosan | 1991 |
Site of anti-inflammatory action of dexamethasone in rabbit skin.
Topics: Animals; Bradykinin; Dactinomycin; Dermatitis, Contact; Dexamethasone; Dinoprostone; Female; Histamine; Leukotriene B4; Male; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Protein Biosynthesis; Rabbits; RNA; Skin; Zymosan | 1991 |
Protein kinase C regulates the synthesis of platelet-activating factor by human monocytes.
Topics: Binding Sites; Calcimycin; Diglycerides; Enzyme Activation; Humans; Kinetics; Leukotriene B4; Monocytes; Opsonin Proteins; Phagocytosis; Platelet Activating Factor; Protein Kinase C; Sphingosine; Tetradecanoylphorbol Acetate; Zymosan | 1991 |
Intravascular chemoattractants inhibit diapedesis by selective receptor occupancy.
Topics: Animals; Blood; Chemotactic Factors; Chemotaxis, Leukocyte; Injections, Intra-Arterial; Leukotriene B4; Male; Neutrophils; Oxidation-Reduction; Rabbits; Receptors, Cell Surface; Thromboxane B2; Zymosan | 1991 |
Metabolism of arachidonic acid in human alveolar macrophages from patients with sarcoidosis.
Topics: Adult; Arachidonic Acid; Arachidonic Acids; Bronchoalveolar Lavage Fluid; Cells, Cultured; Dinoprostone; Humans; Leukotriene B4; Macrophage Activation; Macrophages; Middle Aged; Phagocytosis; Pulmonary Alveoli; Sarcoidosis; Zymosan | 1991 |
Identification of two neutrophil chemotactic peptides produced by porcine alveolar macrophages.
Topics: Amino Acid Sequence; Animals; Base Sequence; Blotting, Northern; Chemotactic Factors; Chemotaxis, Leukocyte; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Chromatography, Liquid; DNA; Interleukin-8; Leukotriene B4; Lipopolysaccharides; Macrophages; Male; Molecular Sequence Data; Neutrophils; Pulmonary Alveoli; Swine; Zymosan | 1991 |
Human fibroblasts release low amounts of reactive oxygen species in response to the potent phagocyte stimulants, serum-treated zymosan, N-formyl-methionyl-leucyl-phenylalanine, leukotriene B4 or 12-O-tetradecanoylphorbol 13-acetate.
Topics: Electron Spin Resonance Spectroscopy; Fibroblasts; Free Radicals; Humans; Hydrogen Peroxide; Leukotriene B4; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Nitroblue Tetrazolium; Oxidation-Reduction; Oxygen; Stimulation, Chemical; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1990 |
Enhanced secretion of prostaglandin E2 by tissue-fixed macrophages in colonic carcinoma.
Topics: Calcimycin; Colon; Colonic Neoplasms; Dinoprostone; Humans; In Vitro Techniques; Leukocytes, Mononuclear; Leukotriene B4; Macrophages; Zymosan | 1990 |
Evidence that a receptor-operated event on the neutrophil mediates neutrophil accumulation in vivo. Pretreatment of 111In-neutrophils with pertussis toxin in vitro inhibits their accumulation in vivo.
Topics: Animals; CD18 Antigens; Cell Adhesion; Cell Aggregation; Cell Degranulation; Complement C5a; Inflammation; Interleukin-1; Interleukin-8; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Rabbits; Receptors, Leukocyte-Adhesion; Recombinant Proteins; Skin; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella; Zymosan | 1990 |
Role of oxidants in ischemia/reperfusion-induced granulocyte infiltration.
Topics: Animals; Catalase; Cats; Chemotaxis, Leukocyte; Deferoxamine; Dimethyl Sulfoxide; Granulocytes; Hydrogen Peroxide; Intestinal Mucosa; Intestine, Small; Ischemia; Leukotriene B4; Muscle, Smooth; Peroxidase; Reperfusion; Superoxide Dismutase; Superoxides; Thiourea; Zymosan | 1990 |
Differential augmentation by recombinant human tumor necrosis factor-alpha of neutrophil responses to particulate zymosan and glucan.
Topics: Glucans; Humans; In Vitro Techniques; Leukotriene B4; Neutrophils; Receptors, Complement; Receptors, Complement 3b; Recombinant Proteins; Signal Transduction; Superoxides; Transcobalamins; Tumor Necrosis Factor-alpha; Up-Regulation; Zymosan | 1990 |
Modulation of alveolar macrophage leukotriene B4 released by complement component C5.
Topics: Antibodies; Antigen-Antibody Complex; Bronchoalveolar Lavage Fluid; Cells, Cultured; Complement C5; Humans; Immunoglobulin Fab Fragments; Leukotriene B4; Lipopolysaccharides; Macrophage Activation; Macrophages; Opsonin Proteins; Pulmonary Alveoli; Zymosan | 1990 |
Zymosan-induced leukotriene B4 generation by human neutrophils is augmented by rhTNF-alpha but not chemotactic peptide.
Topics: Antigens, CD; Cells, Cultured; Complement C3b; Humans; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phagocytosis; Receptors, Complement; Receptors, Complement 3b; Recombinant Proteins; Tumor Necrosis Factor-alpha; Zymosan | 1990 |
Inhibition of neutrophil and eosinophil induced chemotaxis by nedocromil sodium and sodium cromoglycate.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemotaxis, Leukocyte; Cromolyn Sodium; Diterpenes; Eosinophils; Ginkgolides; Humans; In Vitro Techniques; Lactones; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Nedocromil; Neutrophils; Quinolones; Zymosan | 1990 |
Production of arachidonic acid metabolites by caprine alveolar macrophages.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Bronchoalveolar Lavage Fluid; Calcimycin; Fatty Acids, Unsaturated; Goats; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Lipid Metabolism; Macrophages; Zymosan | 1990 |
Effect of staphylococcal delta-toxin and bee venom peptide melittin on leukotriene induction and metabolism of human polymorphonuclear granulocytes.
Topics: Analysis of Variance; Bacterial Toxins; Bee Venoms; Calcimycin; Granulocytes; Humans; Leukotriene B4; Leukotrienes; Melitten; Zymosan | 1990 |
Modulation of arachidonic acid metabolism by bovine alveolar macrophages exposed to interferons and lipopolysaccharide.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Cattle; Dinoprost; Interferon Type I; Leukotriene B4; Lipopolysaccharides; Macrophages; Recombinant Proteins; Thromboxane B2; Zymosan | 1990 |
Macrophages cultured in vitro release leukotriene B4 and neutrophil attractant/activation protein (interleukin 8) sequentially in response to stimulation with lipopolysaccharide and zymosan.
Topics: Calcimycin; Cells, Cultured; Chromatography, High Pressure Liquid; Glucans; Humans; Interleukin-8; Leukotriene B4; Lipopolysaccharides; Macrophages; Masoprocol; Polysaccharides; Radioimmunoassay; Zymosan | 1990 |
The effect of leukotriene B4, leukotriene C4, zymosan activated serum, histamine, tabanid extract and N-formyl-methionyl-leucyl-phenylalanine on the in vitro migration of equine eosinophils.
Topics: Animals; Cell Movement; Cells, Cultured; Chemotactic Factors, Eosinophil; Chemotaxis, Leukocyte; Diptera; Eosinophils; Histamine; Horses; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; SRS-A; Tissue Extracts; Zymosan | 1990 |
Potent and selective inhibition of in vitro lymphocyte migration by cyclosporine and dexamethasone.
Topics: Chemotaxis, Leukocyte; Cyclosporins; Dexamethasone; Humans; In Vitro Techniques; Interleukin-1; Interleukin-2; Leukotriene B4; Lymphocyte Culture Test, Mixed; Lymphocytes; Zymosan | 1990 |
Bacterial adherence and hemolysin production from Escherichia coli induces histamine and leukotriene release from various cells.
Topics: Adhesiveness; Animals; Calcimycin; Chemotactic Factors; Chemotaxis, Leukocyte; Escherichia coli; Hemolysin Proteins; Histamine Release; Humans; Leukotriene B4; Neutrophils; Rats; Species Specificity; SRS-A; Zymosan | 1985 |
Alpha-fetoprotein stimulates leukotriene synthesis in P388D1 macrophages.
Topics: alpha-Fetoproteins; Arachidonic Acids; Calcimycin; Interferon-gamma; Leukotriene B4; Lipopolysaccharides; Macrophage Activation; Macrophages; Prostaglandins; Silicon Dioxide; SRS-A; Tetradecanoylphorbol Acetate; Zymosan | 1986 |
Different patterns of arachidonate metabolism in autologous human blood monocytes and alveolar macrophages.
Topics: Adenosine Triphosphate; Adult; Aerobiosis; Arachidonic Acid; Arachidonic Acids; Calcimycin; Cells, Cultured; Drug Combinations; Female; Humans; Leukotriene B4; Macrophages; Male; Monocytes; Pulmonary Alveoli; SRS-A; Zymosan | 1989 |
Bacterial lipopolysaccharides prime human neutrophils for enhanced production of leukotriene B4.
Topics: Calcimycin; Calcium; Cytosol; Humans; Kinetics; Leukotriene B4; Lipopolysaccharides; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Opsonin Proteins; Oxidation-Reduction; Salmonella; Tetradecanoylphorbol Acetate; Zymosan | 1989 |
Studies on the mechanisms of granulocyte dysfunctions in severely burned patients--evidence for altered leukotriene generation.
Topics: Adult; Aged; Aged, 80 and over; Arachidonic Acid; Arachidonic Acids; Burns; Calcimycin; Chromatography, High Pressure Liquid; Female; Free Radicals; Granulocytes; Humans; Leukotriene B4; Luminescent Measurements; Male; Middle Aged; Oxidation-Reduction; Zymosan | 1989 |
Nedocromil sodium inhibits the A23187- and opsonized zymosan-induced leukotriene formation by human eosinophils but not by human neutrophils.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Asthma; Calcimycin; Eosinophils; Humans; Hypersensitivity; In Vitro Techniques; Leukotriene B4; Nedocromil; Neutrophils; Quinolones; Zymosan | 1989 |
Increased generation of the arachidonic metabolites LTB4 and 5-HETE by human alveolar macrophages in patients with asthma: effect in vitro of nedocromil sodium.
Topics: Adolescent; Adult; Asthma; Bronchoalveolar Lavage Fluid; Calcimycin; Cells, Cultured; Chromatography, High Pressure Liquid; Female; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Macrophages; Male; Middle Aged; Nedocromil; Pulmonary Alveoli; Quinolones; Zymosan | 1989 |
Effects of inadequate vitamin E and/or selenium nutrition on the release of arachidonic acid metabolites in rat alveolar macrophages.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Dinoprostone; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Lipoxygenase; Macrophages; Male; Prostaglandin-Endoperoxide Synthases; Pulmonary Alveoli; Rats; Selenium; Thromboxane B2; Vitamin E; Vitamin E Deficiency; Zymosan | 1989 |
Inhibition of in vitro guinea pig eosinophil chemotaxis by leukotriene B4 antagonist U-75,302.
Topics: Animals; Chemotaxis, Leukocyte; Eosinophils; Guinea Pigs; In Vitro Techniques; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Zymosan | 1989 |
Inhibitory effects of nedocromil sodium on the in vitro induced migration and leukotriene formation of human granulocytes.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Calcimycin; Chemotaxis, Leukocyte; Cromolyn Sodium; Diterpenes; Eosinophils; Ginkgolides; Granulocytes; Humans; In Vitro Techniques; Lactones; Leukotriene B4; Leukotrienes; Nedocromil; Neutrophils; Platelet Activating Factor; Quinolones; SRS-A; Zymosan | 1989 |
Modulation of leukotriene generation by pertussis toxin.
Topics: Adjuvants, Immunologic; Calcimycin; Chromatography, High Pressure Liquid; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Leukotriene B4; Leukotrienes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Opsonin Proteins; Pertussis Toxin; Thionucleotides; Virulence Factors, Bordetella; Zymosan | 1989 |
Release of leukotriene B4 from rat Kupffer cells.
Topics: Animals; Benzoquinones; Calcimycin; Cells, Cultured; Kupffer Cells; Leukotriene B4; Lipoxygenase Inhibitors; Male; Platelet Activating Factor; Quinones; Rats; Rats, Inbred Strains; Zymosan | 1989 |
Granulocyte-macrophage colony-stimulating factor (GM-CSF) and opsonization synergistically enhance leukotriene B4 (LTB4) synthesis induced by phagocytosis in human neutrophils.
Topics: Arachidonate 5-Lipoxygenase; Chromatography, High Pressure Liquid; Colony-Stimulating Factors; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; Humans; In Vitro Techniques; Leukotriene B4; Neutrophils; Opsonin Proteins; Phagocytosis; Zymosan | 1989 |
The in vivo antiinflammatory effects of (E)-2,6-bis(1,1-dimethyl-ethyl)-4-[2-(5-methyl-1H-pyrazol-3-yl)ethenyl ] phenol (PD 127443) a novel dual inhibitor of 5-lipoxygenase and cyclooxygenase.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate Lipoxygenases; Arthritis, Experimental; Carrageenan; Cyclooxygenase Inhibitors; Dinoprost; Edema; Inflammation; Leukemia, Basophilic, Acute; Leukotriene B4; Lipoxygenase Inhibitors; Mycobacterium; Phenols; Pyrazoles; Rats; Stomach Ulcer; Tumor Cells, Cultured; Zymosan | 1989 |
Platelet-activating factor and leukotriene biosynthesis in whole blood. A model for the study of transcellular arachidonate metabolism.
Topics: Arachidonic Acids; Humans; Leukotriene B4; Leukotrienes; Models, Biological; Phagocytes; Phagocytosis; Platelet Activating Factor; Thromboxane B2; Zymosan | 1989 |
Effects of sulfasalazine and a sulfasalazine analogue on the formation of lipoxygenase and cyclooxygenase products.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Aminosalicylic Acid; Aminosalicylic Acids; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcimycin; Chromatography, High Pressure Liquid; Dinoprostone; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Leukocytes; Leukotriene B4; Lipoxygenase; Mesalamine; Prostaglandin-Endoperoxide Synthases; Sulfapyridine; Sulfasalazine; Zymosan | 1989 |
Relative contribution of leukotriene B4 to the neutrophil chemotactic activity produced by the resident human alveolar macrophage.
Topics: Calcimycin; Chemotactic Factors; Chemotaxis, Leukocyte; Humans; Leukotriene B4; Macrophages; Masoprocol; Methionine; Neutrophils; Platelet Activating Factor; Pulmonary Alveoli; Zymosan | 1987 |
Neutrophil chemotactic activity produced by normal and activated human bronchoalveolar lavage cells.
Topics: Bronchoalveolar Lavage Fluid; Cell Separation; Cells, Cultured; Centrifugation, Density Gradient; Chemotactic Factors; Chemotaxis, Leukocyte; Chromatography, High Pressure Liquid; Complement C3; Complement C3a; Complement C5; Complement C5a; Humans; Interleukin-1; Leukotriene B4; Macrophage Activation; Macrophages; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Radioimmunoassay; Sarcoidosis; Zymosan | 1987 |
Leukotriene B4 paradox: neutrophils can, but will not, respond to ligand-receptor interactions by forming leukotriene B4 or its omega-metabolites.
Topics: Adult; Arachidonic Acid; Arachidonic Acids; Humans; Immunoglobulin G; In Vitro Techniques; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase C; Receptors, Immunologic; Zymosan | 1987 |
Comparative study of natural and synthetic retinoids as inhibitors of arachidonic acid release and metabolism in rat peritoneal macrophages.
Topics: Animals; Calcimycin; Dinoprostone; Fatty Acids, Unsaturated; In Vitro Techniques; Leukotriene B4; Lipoxygenase Inhibitors; Macrophages; Male; Peritoneal Lavage; Phospholipases A; Prostaglandins E; Rats; Rats, Inbred Strains; Retinoids; Tetradecanoylphorbol Acetate; Thromboxane B2; Zymosan | 1987 |
Modulation of zymosan stimulated leukotriene release by dietary unsaturated fatty acids.
Topics: Animals; Dietary Fats; Dinoprostone; Fatty Acids, Unsaturated; Inflammation; Leukotriene B4; Macrophages; Mice; Prostaglandins E; SRS-A; Zymosan | 1987 |
Effects of immune complexes, zymosan preparations and ionophore A 23187 on leukotriene formation in human leukocytes.
Topics: Antigen-Antibody Complex; Calcimycin; Humans; In Vitro Techniques; Leukocytes; Leukotriene B4; Opsonin Proteins; SRS-A; Zymosan | 1987 |
L-ascorbic acid modulates 5-lipoxygenase activity in human polymorphonuclear leukocytes.
Topics: Arachidonate 5-Lipoxygenase; Arachidonate Lipoxygenases; Ascorbic Acid; Biological Transport; Enzyme Activation; Humans; Leukotriene B4; Neutrophils; Zymosan | 1988 |
LTB4 production and lysosomal enzyme release by rat alveolar macrophages: effects of phagocytosis, receptor binding, and ionophore stimulation.
Topics: Animals; Calcimycin; Chromatography, High Pressure Liquid; Leukotriene B4; Lysosomes; Macrophages; Masoprocol; Phagocytosis; Pulmonary Alveoli; Rabbits; Rats; Rats, Inbred Strains; Receptors, Complement; Receptors, Fc; Tetradecanoylphorbol Acetate; Zymosan | 1987 |
Modulation of leukotriene release from human polymorphonuclear leucocytes by PMA and arachidonic acid.
Topics: Arachidonic Acids; Calcimycin; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Activation; Granulocytes; Humans; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase C; SRS-A; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Zymosan | 1988 |
Potentiation of neutrophil aggregation by human leukocyte inhibitory factor.
Topics: Cell Aggregation; Cells, Cultured; Humans; Leukotriene B4; Lymphokines; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Zymosan | 1988 |
Hydrogen peroxide inhibits alveolar macrophage 5-lipoxygenase metabolism in association with depletion of ATP.
Topics: Adenosine Triphosphate; Animals; Arachidonate Lipoxygenases; Calcimycin; Cells, Cultured; Chromatography, High Pressure Liquid; Female; Hydrogen Peroxide; Kinetics; Leukotriene B4; Lipoxygenase Inhibitors; Macrophages; Rats; Rats, Inbred Strains; Thromboxane B2; Zymosan | 1988 |
Perturbation of beta-glucan receptors on human neutrophils initiates phagocytosis and leukotriene B4 production.
Topics: Cytochalasin B; Glucans; Humans; Leukotriene B4; Mannans; Neutrophils; Opsonin Proteins; Phagocytosis; Receptors, Cell Surface; Receptors, Immunologic; Trypsin; Vinblastine; Zymosan | 1988 |
Differential neutrophil activation before and after endotoxin infusion in enterally versus parenterally fed volunteers.
Topics: Chemotaxis; Complement Activation; Complement C3; Endotoxins; Enteral Nutrition; Hydrocortisone; Infusions, Intravenous; Kinetics; Lactoferrin; Leukocyte Count; Leukotriene B4; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Parenteral Nutrition; Time Factors; Tumor Necrosis Factor-alpha; Zymosan | 1988 |
Tumor necrosis factor-enhanced leukotriene B4 generation and chemotaxis in human neutrophils.
Topics: Calcimycin; Cells, Cultured; Chemotaxis, Leukocyte; Dose-Response Relationship, Drug; Endotoxins; Escherichia coli; Humans; In Vitro Techniques; Injections, Intravenous; Leukotriene B4; Lipopolysaccharides; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Stimulation, Chemical; Time Factors; Tumor Necrosis Factor-alpha; Zymosan | 1988 |
Arachidonic acid metabolism by a vitamin D3-differentiated human leukemic cell line.
Topics: Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcitriol; Cell Division; Cell Fractionation; Dimethyl Sulfoxide; Humans; Leukemia; Leukotriene B4; Lipids; N-Formylmethionine Leucyl-Phenylalanine; Radioimmunoassay; Thromboxane B2; Tumor Cells, Cultured; Zymosan | 1988 |
Enhanced generation of leukotriene B4 by neutrophils stimulated by unopsonized zymosan and by calcium ionophore after exercise-induced asthma.
Topics: Adolescent; Adult; Airway Resistance; Arachidonate 5-Lipoxygenase; Asthma; Asthma, Exercise-Induced; Bronchial Provocation Tests; Calcimycin; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Female; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; Neutrophils; Stereoisomerism; Zymosan | 1988 |
Production of prostacyclin in mice following intraperitoneal injection of acetic acid, phenylbenzoquinone and zymosan: its role in the writhing response.
Topics: Acetates; Analgesics; Animals; Benzoquinones; Dinoprostone; Epoprostenol; Leukotriene B4; Male; Mice; Pain; Quinones; Radioimmunoassay; Reference Values; Zymosan | 1988 |
Intracellular retention of the 5-lipoxygenase pathway product, leukotriene B4, by human neutrophils activated with unopsonized zymosan.
Topics: Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Calcimycin; Humans; Hydroxyeicosatetraenoic Acids; Kinetics; Leukotriene B4; Lipoxygenase; Neutrophils; Opsonin Proteins; Phagocytosis; Zymosan | 1985 |
Studies of leukotriene B4-specific binding and function in rat polymorphonuclear leukocytes: absence of a chemotactic response.
Topics: Animals; Binding Sites; Binding, Competitive; Chemotaxis, Leukocyte; Humans; Kinetics; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Rats; Rats, Inbred Strains; Time Factors; Zymosan | 1985 |
Generation of leukotrienes by human monocytes upon stimulation of their beta-glucan receptor during phagocytosis.
Topics: Complement Pathway, Alternative; Glucans; Humans; In Vitro Techniques; Leukotriene B4; Mannans; Monocytes; Phagocytosis; Receptors, Cell Surface; Receptors, Immunologic; SRS-A; Zymosan | 1985 |
Evaluation of inhibitors of eicosanoid synthesis in leukocytes: possible pitfall of using the calcium ionophore A23187 to stimulate 5' lipoxygenase.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Arachidonate Lipoxygenases; Calcimycin; Humans; Leukotriene B4; Lipoxygenase; Neutrophils; Propionates; Pyrazoles; Thromboxane B2; Zymosan | 1985 |
Stimulus-specific neutrophil aggregation: evaluation of possible mechanisms for the stimulus-response apparatus.
Topics: Calcimycin; Cell Aggregation; Cytoskeleton; Humans; Hydrogen Peroxide; In Vitro Techniques; Leukotriene B4; Microtubules; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen; Peroxidase; Prostaglandin-Endoperoxide Synthases; Time Factors; Zymosan | 1985 |
Exclusive leukotriene C4 synthesis by purified human eosinophils induced by opsonized zymosan.
Topics: Calcimycin; Eosinophils; Humans; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Opsonin Proteins; Platelet Activating Factor; SRS-A; Zymosan | 1985 |
Selective inhibition of leukotriene B4 biosynthesis in rat pulmonary alveolar macrophages by dietary selenium deficiency.
Topics: Animals; Arachidonate Lipoxygenases; Diet; Dinoprostone; Glutathione Peroxidase; Leukotriene B4; Lipoxygenase; Liver; Macrophages; Male; Opsonin Proteins; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; Pulmonary Alveoli; Rats; Rats, Inbred F344; Selenium; Thromboxane B2; Zymosan | 1985 |
Modulation of the generation and release of leukotrienes from leukocytes.
Topics: Arachidonate Lipoxygenases; Arachidonic Acids; Humans; Leukocytes; Leukotriene A4; Leukotriene B4; Lipoxygenase; Macrophages; Monocytes; Neutrophils; SRS-A; Zymosan | 1985 |
Intraperitoneal injection of zymosan in mice induces pain, inflammation and the synthesis of peptidoleukotrienes and prostaglandin E2.
Topics: Animals; Arachidonate Lipoxygenases; Cell Aggregation; Dinoprostone; In Vitro Techniques; Indomethacin; Inflammation; Injections, Intraperitoneal; Leukotriene B4; Leukotriene E4; Lipoxygenase; Male; Mice; Mice, Inbred Strains; Pain; Prostaglandins E; Proteins; SRS-A; Zymosan | 1985 |
Leukotriene B4 production by stimulated whole blood: comparative studies with isolated polymorphonuclear cells.
Topics: Calcimycin; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Leukotriene B4; Lipoxygenase Inhibitors; Neutrophils; Zymosan | 1986 |
Enhanced release of hydrogen peroxide and metabolites of arachidonic acid by macrophages from SENCAR mice following stimulation with phorbol esters.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Caseins; Hydrogen Peroxide; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Macrophages; Mice; Mice, Inbred Strains; Phorbol Esters; Prostaglandins; SRS-A; Zymosan | 1986 |
Migration in vitro by blood and exudate neutrophils assessed serially during an inflammatory response.
Topics: Animals; Cell Migration Inhibition; Cell Movement; Exudates and Transudates; Inflammation; Leukotriene B4; Neutrophils; Swine; Zymosan | 1986 |
Relationship of glucocorticoid suppression of arachidonic acid metabolism to alteration of neutrophil function.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Cattle; Dexamethasone; Diglycerides; Hydroxyeicosatetraenoic Acids; Indomethacin; Leukotriene B4; Masoprocol; Neutrophils; Phospholipids; Pyrazoles; Triglycerides; Zymosan | 1987 |
The effect of leukotrienes on porcine alveolar macrophage function.
Topics: Acetylglucosaminidase; Animals; Arylsulfatases; Leukotriene B4; Leukotriene E4; Macrophage Activation; Macrophages; Pulmonary Alveoli; SRS-A; Superoxides; Swine; Tetradecanoylphorbol Acetate; Zymosan | 1986 |
The leukotriene B4 paradox: neutrophils can, but will not, respond to ligand-receptor interactions by forming leukotriene B4 or its omega-metabolites.
Topics: Arachidonic Acid; Arachidonic Acids; Humans; Immunoglobulin G; Leukotriene B4; Ligands; Linoleic Acid; Linoleic Acids; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Receptors, Drug; Tetradecanoylphorbol Acetate; Zymosan | 1987 |
Independent regulation of leukotriene B4-elicited polymorphonuclear leukocyte exocytosis and superoxide generation by a serum factor.
Topics: Exocytosis; Glucuronidase; Humans; Ibuprofen; Leukopenia; Leukotriene B4; Lupus Erythematosus, Systemic; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Stimulation, Chemical; Superoxides; Zymosan | 1987 |
Inhibition by methylprednisolone of zymosan-induced leukotriene synthesis in alveolar macrophages.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Chromatography, High Pressure Liquid; Depression, Chemical; Female; Gonadal Steroid Hormones; Leukotriene B4; Macrophages; Methylprednisolone; Pulmonary Alveoli; Radioimmunoassay; Rats; Rats, Inbred Strains; SRS-A; Thromboxane B2; Zymosan | 1987 |
Multiwell cap assay: a simple objective method for the assessment of leukocyte locomotion in vitro.
Topics: Chemotaxis, Leukocyte; Cytological Techniques; Humans; In Vitro Techniques; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Zymosan | 1986 |
Interferon-alpha enhances the production of leukotriene B4 in murine peritoneal macrophages stimulated by opsonized zymosan.
Topics: Animals; Dinoprostone; Female; Interferon Type I; Leukotriene B4; Macrophages; Mice; Mice, Inbred C57BL; Prostaglandins E; Zymosan | 1987 |
Effect of group B streptococcal type-specific antigen on polymorphonuclear leukocyte function and polymorphonuclear leukocyte-endothelial cell interaction.
Topics: Antigens, Bacterial; Cell Adhesion; Cells, Cultured; Chemotaxis, Leukocyte; Complement System Proteins; Endothelium; Humans; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Streptococcus agalactiae; Zymosan | 1987 |
Desensitization of acute inflammatory lesions to chemotaxins and endotoxin.
Topics: Acute Disease; Animals; Caseins; Chemotactic Factors; Desensitization, Immunologic; Dose-Response Relationship, Immunologic; Endotoxins; Female; Inflammation; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Rabbits; Zymosan | 1984 |
Leukotriene B4, polymorphonuclear leukocytes and inflammatory exudates in the rat.
Topics: Animals; Antibody Specificity; Calcimycin; Carrageenan; Chromatography, High Pressure Liquid; Exudates and Transudates; Indomethacin; Inflammation; Leukocyte Count; Leukotriene B4; Neutrophils; Rats; SRS-A; Zymosan | 1984 |
Dexamethasone inhibits the production of thromboxane B2 and leukotriene B4 by human alveolar and peritoneal macrophages in culture.
Topics: Acetylglucosaminidase; Ascites; Cells, Cultured; Dexamethasone; Humans; Leukotriene B4; Macrophages; Pulmonary Alveoli; Thromboxane B2; Thromboxanes; Zymosan | 1984 |
Serum-coated zymosan stimulates the synthesis of leukotriene B4 in human polymorphonuclear leukocytes. Inhibition by cyclic AMP.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Arachidonic Acids; Chromatography, High Pressure Liquid; Cyclic AMP; Epoprostenol; Gas Chromatography-Mass Spectrometry; Humans; In Vitro Techniques; Leukotriene B4; Neutrophils; Zymosan | 1981 |
Leukotriene B4 biosynthesis by alveolar macrophages.
Topics: Animals; Antioxidants; Arachidonic Acids; Calcimycin; Calcium; Catechols; Cells, Cultured; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Leukotriene B4; Macrophages; Masoprocol; Rabbits; Tetradecanoylphorbol Acetate; Zymosan | 1982 |
Identification of two monohydroxyeicosatetraenoic acids synthesized by human pulmonary macrophages.
Topics: Adult; Arachidonic Acid; Arachidonic Acids; Calcimycin; Chromatography, High Pressure Liquid; Female; Humans; Leukotriene B4; Lipoxygenase; Lung; Macrophages; Male; Stimulation, Chemical; Zymosan | 1982 |
Role of prostaglandins and leukotrienes in complement-initiated lung vascular injury.
Topics: Animals; Catechols; Complement Activation; Epoprostenol; Hypertension, Pulmonary; Hypoxia; Leukocytes; Leukotriene B4; Masoprocol; Meclofenamic Acid; ortho-Aminobenzoates; Oxygenases; Prostaglandins; Pulmonary Circulation; Sheep; Zymosan | 1983 |
Release of leukotriene B4 from human neutrophils and its relationship to degranulation induced by N-formyl-methionyl-leucyl-phenylalanine, serum-treated zymosan and the ionophore A23187.
Topics: Anti-Bacterial Agents; Arachidonic Acids; Calcimycin; Cells, Cultured; Cytoplasmic Granules; Dose-Response Relationship, Drug; Glucuronidase; Humans; Leukotriene B4; Methionine; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Thromboxane B2; Zymosan | 1983 |
The effect of eosinophil chemotactic factors on in vitro eosinopoiesis in the guinea pig.
Topics: Animals; Cells, Cultured; Chemotactic Factors; Chemotactic Factors, Eosinophil; Dipeptides; Eosinophils; Guinea Pigs; Hematopoiesis; Hematopoietic Stem Cells; Leukotriene B4; Zymosan | 1983 |
Physiological and pharmacological regulation of prostaglandin and leukotriene production by macrophages.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Cyclooxygenase Inhibitors; Dapsone; Leukotriene B4; Macrophages; Mice; Prostaglandins; Sulindac; Zymosan | 1984 |
The in vivo effect of leukotriene B4 on polymorphonuclear leukocytes and the microcirculation. Comparison with activated complement (C5a des Arg) and enhancement by prostaglandin E2.
Topics: Animals; Capillary Permeability; Cell Movement; Chemotactic Factors; Complement C5; Complement C5a, des-Arginine; Dermatitis; Dinoprostone; Female; Hemorrhage; Leukotriene B4; Microcirculation; Neutrophils; Prostaglandins E; Rabbits; Regional Blood Flow; Scintillation Counting; Zymosan | 1984 |
Release of leukotrienes by human monocytes on stimulation of their phagocytic receptor for particulate activators.
Topics: Arachidonic Acid; Arachidonic Acids; Calcimycin; Erythrocytes; Humans; Leukotriene B4; Monocytes; Opsonin Proteins; Phagocytosis; Receptors, IgG; Receptors, Immunologic; Trypsin; Zymosan | 1984 |
Trimetazidine inhibits neutrophil accumulation after myocardial ischaemia and reperfusion in rabbits.
Topics: Animals; Blood Pressure; Capillary Permeability; Disease Models, Animal; Heart Rate; Interleukin-8; Leukotriene B4; Male; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Neutrophils; Rabbits; Trimetazidine; Zymosan | 1993 |
Bacterial lipopolysaccharide primes human neutrophils for enhanced release of arachidonic acid and causes phosphorylation of an 85-kD cytosolic phospholipase A2.
Topics: Acute-Phase Proteins; Alkaloids; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Arachidonic Acid; Carrier Proteins; CHO Cells; Cricetinae; Cricetulus; Cytosol; Humans; Leukotriene B4; Lipopolysaccharide Receptors; Lipopolysaccharides; Membrane Glycoproteins; Neutrophils; Phospholipases A; Phospholipases A2; Phospholipids; Phosphorylation; Staurosporine; Tetradecanoylphorbol Acetate; Zymosan | 1994 |
Human neutrophils are selectively activated by independent ligation of the subunits of the CD11b/CD18 integrin.
Topics: Antibodies, Monoclonal; CD18 Antigens; Epitope Mapping; Epitopes; Humans; Immunoglobulin G; Leukotriene B4; Macromolecular Substances; Macrophage-1 Antigen; Neutrophil Activation; Neutrophils; Phagocytosis; Receptors, Fc; Stimulation, Chemical; Zymosan | 1994 |
Stimulus-dependent effects of CI-986 on arachidonic acid metabolism by human neutrophils.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Calcimycin; Chromatography, High Pressure Liquid; Humans; Leukotriene B4; Linear Models; Lipoxygenase Inhibitors; Lysosomes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Respiratory Burst; Thiadiazoles; Thromboxane B2; Zymosan | 1995 |
Characterization and pharmacological modulation of antigen-induced peritonitis in actively sensitized mice.
Topics: Animals; Benzeneacetamides; Cetirizine; Cycloheximide; Dexamethasone; Eosinophils; Histamine Release; Hydroxamic Acids; Indomethacin; Kinetics; Leukocyte Count; Leukotriene B4; Leukotriene C4; Lipoxygenase Inhibitors; Male; Mice; Mice, Inbred BALB C; Ovalbumin; Peritoneal Cavity; Peritonitis; Platelet Activating Factor; T-Lymphocytes; Tacrolimus; Terfenadine; Thiazoles; Zymosan | 1993 |
Separation of neutrophils from blood in human and laboratory animals and comparison of the chemotaxis.
Topics: Animals; Ascitic Fluid; Cell Migration Inhibition; Cell Separation; Chemotactic Factors; Chemotaxis, Leukocyte; Dogs; Female; Humans; Interleukin-8; Leukotriene B4; Macaca mulatta; Male; Mice; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Rabbits; Rats; Recombinant Proteins; Species Specificity; Zymosan | 1995 |
Differential effects of the PAF receptor antagonist UK-74,505 on neutrophil and eosinophil accumulation in guinea-pig skin.
Topics: Animals; Blood Proteins; Calcium; Dihydropyridines; Edema; Eosinophils; Female; Guinea Pigs; Imidazoles; Leukotriene B4; Neutrophils; Passive Cutaneous Anaphylaxis; Peritoneal Cavity; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Skin; Zymosan | 1994 |
Impaired leukotriene B4 release by neonatal polymorphonuclear leukocytes.
Topics: Adult; Aging; Calcimycin; Fetal Blood; Humans; Infant, Newborn; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Zymosan | 1994 |
In vivo characterization of zymosan-induced mouse peritoneal inflammation.
Topics: Acetophenones; Animals; Arachidonate 5-Lipoxygenase; Benzopyrans; Complement C5a; Leukotriene B4; Male; Mast Cells; Mice; Peritonitis; Peroxidase; Tetrazoles; Zymosan | 1994 |
Leukotriene B4 and C4 generation by blood leukocytes after ex vivo stimulation by Ca-ionophore and opsonized zymosan in children with atopic dermatitis.
Topics: Adolescent; Calcimycin; Child; Child, Preschool; Dermatitis, Atopic; Eosinophils; Female; Humans; Leukocyte Count; Leukocytes; Leukotriene B4; Leukotriene C4; Male; Zymosan | 1994 |
Effects of pancreatic and snake venom phospholipase A2 on the generation of leukotriene B4 and C4 by human leukocytes in vitro.
Topics: Humans; Leukocytes; Leukotriene B4; Leukotriene C4; Opsonin Proteins; Pancreas; Phospholipases A; Phospholipases A2; Quinacrine; Snake Venoms; Zymosan | 1994 |
Reverse-phase high-performance liquid chromatography analysis of arachidonic acid metabolites in plasma after stimulation of whole blood ex vivo.
Topics: Aged; Animals; Anticoagulants; Arachidonic Acid; Calcimycin; Chromatography, High Pressure Liquid; Eosinophils; Female; Humans; Indoles; Kinetics; Leukotriene Antagonists; Leukotriene B4; Middle Aged; Quinolines; Rabbits; Spectrophotometry, Ultraviolet; Stimulation, Chemical; Synovial Fluid; Time Factors; Zymosan | 1994 |
In vitro pharmacology of BAY X1005, a new inhibitor of leukotriene synthesis.
Topics: Animals; Arachidonic Acid; Calcimycin; Cells, Cultured; Humans; Leukotriene B4; Leukotriene C4; Lipoxygenase Inhibitors; Macrophages, Peritoneal; Methemoglobin; Mice; Mice, Inbred BALB C; Neutrophils; Quinolines; Rats; Rats, Wistar; Reactive Oxygen Species; Stereoisomerism; Xanthine Oxidase; Zymosan | 1993 |
Peritoneal dialysis fluid inhibition of polymorphonuclear leukocyte respiratory burst activation is related to the lowering of intracellular pH.
Topics: Cells, Cultured; Cytoplasm; Dialysis Solutions; Electrolytes; Evaluation Studies as Topic; Humans; Hydrogen-Ion Concentration; Intracellular Fluid; Lactates; Lactic Acid; Leukotriene B4; Luminescent Measurements; Neutrophils; Peritoneal Dialysis; Phagocytosis; Respiratory Burst; Stimulation, Chemical; Zymosan | 1993 |
Cloricromene inhibits leukotriene formation by human polymorphonuclear leucocytes by suppressing arachidonate release from membrane phospholipids.
Topics: Arachidonic Acid; Calcimycin; Chromonar; Dose-Response Relationship, Drug; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Membrane Lipids; Neutrophils; Phospholipids; SRS-A; Zymosan | 1993 |
A monoclonal antibody recognizing very late activation antigen-4 inhibits eosinophil accumulation in vivo.
Topics: Animals; Antibodies, Monoclonal; Edema; Eosinophils; Guinea Pigs; Inflammation; Leukotriene B4; Passive Cutaneous Anaphylaxis; Platelet Activating Factor; Receptors, Very Late Antigen; Zymosan | 1993 |
Inhibitory effects of amide local anaesthetics on stimulus-induced human leukocyte metabolic activation, LTB4 release and IL-1 secretion in vitro.
Topics: Antigen-Antibody Complex; Bupivacaine; Cells, Cultured; Dose-Response Relationship, Drug; Granulocytes; Humans; Interleukin-1; Leukocytes, Mononuclear; Leukotriene B4; Lidocaine; Luminescent Measurements; Luminol; Zymosan | 1993 |
Characterization of the inhibitory prostanoid receptors on human neutrophils.
Topics: Humans; Hydantoins; In Vitro Techniques; Leukotriene B4; Misoprostol; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Prostaglandin Antagonists; Prostaglandins; Prostanoic Acids; Receptors, Prostaglandin; Superoxides; Xanthenes; Xanthones; Zymosan | 1993 |
Effect of dexamethasone on neutrophil accumulation and oedema formation in rabbit skin: an investigation of site of action.
Topics: Animals; Anti-Inflammatory Agents; Blood Proteins; Dexamethasone; Dinoprostone; Edema; Indium Radioisotopes; Leukotriene B4; Male; Microcirculation; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Binding; Rabbits; Regional Blood Flow; Skin; Zymosan | 1993 |
Impaired superoxide anion, platelet-activating factor, and leukotriene B4 synthesis by neutrophils in cirrhosis.
Topics: Adult; Aged; Arachidonic Acid; Calcimycin; Female; Humans; Leukotriene B4; Liver Cirrhosis; Male; Mass Spectrometry; Middle Aged; Neutrophils; Platelet Activating Factor; Superoxides; Zymosan | 1993 |
Inhibition of the production of platelet activating factor and of leukotriene B4 in activated neutrophils by nimesulide due to an elevation of intracellular cyclic adenosine monophosphate.
Topics: 1-Methyl-3-isobutylxanthine; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytochalasin B; Enzyme Inhibitors; Humans; In Vitro Techniques; Isoquinolines; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphodiesterase Inhibitors; Platelet Activating Factor; Protein Kinase Inhibitors; Sulfonamides; Zymosan | 1995 |
The effect of leukotriene synthesis inhibitors in models of acute and chronic inflammation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Chronic Disease; Disease Models, Animal; Drug Combinations; Exudates and Transudates; Female; Hydroxyurea; Inflammation; Leukotriene B4; Lipoxygenase; Lipoxygenase Inhibitors; Male; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Naproxen; Prostaglandin-Endoperoxide Synthases; Quinolines; Time Factors; Zymosan | 1996 |
Involvement of secretory phospholipase A2 activity in the zymosan rat air pouch model of inflammation.
Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents; Colchicine; Dinoprostone; Homosteroids; Inflammation; Leukotriene B4; Male; Neutrophils; Peroxidase; Phospholipases A; Phospholipases A2; Rats; Rats, Wistar; Sesterterpenes; Terpenes; Zymosan | 1996 |
Parameters of respiratory burst and arachidonic acid metabolism in polymorphonuclear granulocytes from patients with various thyroid diseases.
Topics: Adenoma; Adult; Arachidonic Acids; Calcimycin; Candida albicans; Dinoprostone; Female; Graves Disease; Humans; In Vitro Techniques; Leukotriene B4; Leukotriene C4; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Phagocytosis; Reference Values; Respiratory Burst; Superoxides; Thyroid Neoplasms; Thyroiditis, Autoimmune; Thyroxine; Zymosan | 1996 |
Leukotriene B4 and C4 generation by human leukocytes after ex vivo stimulation with Ca-ionophore and opsonized zymosan in children with atopic asthma.
Topics: Adolescent; Asthma; Calcimycin; Child; Child, Preschool; Humans; Hypersensitivity, Immediate; Immunoglobulin E; Leukocytes; Leukotriene B4; Leukotriene C4; Opsonin Proteins; Zymosan | 1995 |
Priming of eosinophil recruitment in vivo by LPS pretreatment.
Topics: Animals; Antibodies, Monoclonal; Antigens, CD; Azepines; CD18 Antigens; Chemotactic Factors, Eosinophil; Chemotaxis, Leukocyte; Complement C5a, des-Arginine; Cycloheximide; Drug Synergism; Edema; Eosinophilia; Eosinophils; Female; Guinea Pigs; Immunoglobulin G; Interleukin 1 Receptor Antagonist Protein; Leukocyte Count; Leukotriene B4; Lipopolysaccharides; Lipoxygenase Inhibitors; Neutrophils; Passive Cutaneous Anaphylaxis; Platelet Activating Factor; Protein Synthesis Inhibitors; Pyrans; Quinolones; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Recombinant Fusion Proteins; Sialoglycoproteins; Skin; Triazoles; Zymosan | 1996 |
Involvement of leukotriene B4 in zymosan-induced rat pleurisy: inhibition of leukocyte infiltration by the 5-lipoxygenase inhibitor T-0757.
Topics: Amides; Animals; Benzoquinones; Guinea Pigs; Indomethacin; Leukocytes; Leukotriene B4; Lipoxygenase Inhibitors; Male; Pleurisy; Rats; Rats, Wistar; Zymosan | 1995 |
Effect of bakuchiol on leukocyte functions and some inflammatory responses in mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Survival; Dinoprostone; Edema; Humans; In Vitro Techniques; Inflammation; Leukocyte Elastase; Leukocytes; Leukotriene B4; Male; Mice; Neutrophils; Peroxidase; Phenols; Phospholipases A; Phospholipases A2; Superoxides; Thromboxane B2; Zymosan | 1996 |
CD11b/CD18-dependent stimulation of leukotriene B4 synthesis by human neutrophils (PMN) is synergistically enhanced by tumour necrosis factor alpha and low dose diacylglycerol.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Diglycerides; Humans; Leukotriene B4; Macrophage-1 Antigen; Neutrophils; Phagocytosis; Protein Kinase C; Staurosporine; Tumor Necrosis Factor-alpha; Up-Regulation; Zymosan | 1996 |
Quantitation of 5-lipoxygenase products by electrospray mass spectrometry: effect of ethanol on zymosan-stimulated production of 5-lipoxygenase products by human neutrophils.
Topics: Arachidonate 5-Lipoxygenase; Chromatography, High Pressure Liquid; Ethanol; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Mass Spectrometry; Neutrophils; Zymosan | 1997 |
Release of prostaglandin E2 and leukotriene B4 by alveolar macrophages from patients with sarcoidosis.
Topics: Adult; Bronchoalveolar Lavage Fluid; Cell Count; Cells, Cultured; Cyclooxygenase Inhibitors; Female; Humans; Indomethacin; Leukotriene B4; Lymphocyte Count; Macrophages, Alveolar; Male; Prostaglandins E; Sarcoidosis; Zymosan | 1997 |
Tenidap inhibits 5-lipoxygenase product formation in vitro, but this activity is not observed in three animal models.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Calcimycin; Chemotactic Factors; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Erythrocytes; Humans; Hydroxyeicosatetraenoic Acids; Immunoenzyme Techniques; Indoles; Ionophores; Leukemia, Basophilic, Acute; Leukotriene B4; Leukotriene E4; Lipoxygenase Inhibitors; Neutrophil Activation; Neutrophils; Oxindoles; Rabbits; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Thromboxane B2; Zymosan | 1997 |
Effects of ropivacaine on eicosanoid release from human granulocytes and endothelial cells in vitro.
Topics: 6-Ketoprostaglandin F1 alpha; Amides; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cells, Cultured; Eicosanoids; Endothelium, Vascular; Granulocytes; Humans; Hydrocortisone; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Lidocaine; Mesalamine; Ropivacaine; Thrombin; Zymosan | 1997 |
Ambroxol inhibits histamine release from human adenoidal mast cells.
Topics: Adenoids; Ambroxol; Anti-Allergic Agents; Dose-Response Relationship, Drug; Expectorants; Granulocytes; Histamine Release; Humans; Leukotriene B4; Mast Cells; Monocytes; p-Methoxy-N-methylphenethylamine; Skin; Superoxides; Zymosan | 1998 |
The preclinical pharmacological profile of the potent and selective leukotriene B4 antagonist CP-195543.
Topics: Animals; Arthritis; Cell Adhesion Molecules; Chemotactic Factors; Chemotaxis; Chromans; Collagen; Drug Evaluation, Preclinical; Humans; Interleukin-1; Leukotriene B4; Macrophage-1 Antigen; Mice; Mice, Inbred BALB C; Monocytes; Neutrophils; Prostaglandins; Spleen; Zymosan | 1998 |
Exogenous leukotriene B4 (LTB4) inhibits human neutrophil generation of LTB4 from endogenous arachidonic acid during opsonized zymosan phagocytosis.
Topics: Arachidonic Acid; Dose-Response Relationship, Drug; Fatty Alcohols; Glycols; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Neutrophils; Phagocytosis; Zymosan | 1998 |
Cell wall preparations from environmental yeasts: effect on alveolar macrophage function in vitro.
Topics: Agricultural Workers' Diseases; Animals; Dose-Response Relationship, Drug; Dust; Leukotriene B4; Lung; Macrophages, Alveolar; Phagocytosis; Pneumonia; Rats; Rats, Sprague-Dawley; Sheep; Superoxides; Syndrome; Tumor Necrosis Factor-alpha; Yeasts; Zymosan | 1998 |
An anti-inflammatory ditriazine inhibiting leukocyte functions and expression of inducible nitric oxide synthase and cyclo-oxygenase-2.
Topics: Animals; Anti-Inflammatory Agents; Blood Platelets; Carrageenan; Cell-Free System; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Edema; Female; Hindlimb; Humans; Inflammation; Isoenzymes; Leukocytes; Leukotriene B4; Luminescent Measurements; Macrophages, Peritoneal; Membrane Proteins; Mice; Microsomes; Neutrophil Activation; Neutrophils; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Pancreatic Elastase; Phospholipases A; Prostaglandin-Endoperoxide Synthases; Thromboxane B2; Triazines; Zymosan | 2000 |
Modulation of haem oxygenase-1 expression by nitric oxide and leukotrienes in zymosan-activated macrophages.
Topics: Amidines; Animals; Benzylamines; Cell Line; Chick Embryo; Cyclooxygenase 2; Dexamethasone; Dinoprostone; Dose-Response Relationship, Drug; Eicosanoids; Enzyme Inhibitors; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Hydroxyurea; Indomethacin; Isoenzymes; Leukotriene B4; Leukotriene C4; Leukotrienes; Macrophage Activation; Macrophages; NF-kappa B; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Protein Binding; Pyrans; Quinolones; Sulfonamides; Time Factors; Transcription Factor AP-1; Zymosan | 2001 |
Sesquiterpene glucosides from anti-leukotriene B4 release fraction of Taraxacum officinale.
Topics: Anti-HIV Agents; Asteraceae; Calcimycin; Cells, Cultured; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Crystallography, X-Ray; Dose-Response Relationship, Drug; Glucosides; HeLa Cells; HIV-1; Humans; Inflammation; Japan; Leukotriene B4; Molecular Conformation; Molecular Structure; Neutrophils; Nuclear Magnetic Resonance, Biomolecular; Plant Extracts; Plant Roots; Plants, Medicinal; Sesquiterpenes; Stereoisomerism; Structure-Activity Relationship | 2001 |
Agonist-dependent failure of neutrophil function in diabetes correlates with extent of hyperglycemia.
Topics: Adult; Blood Glucose; Calcimycin; Cells, Cultured; Cross-Sectional Studies; Diabetes Mellitus; Female; Humans; Hyperglycemia; Leukotriene B4; Lysosomes; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Zymosan | 2001 |
Effect of some hexahydroimidazo[1,2-c]pyrimidines in inflammatory responses involving leucocytes and macrophages.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Dinoprostone; Edema; Female; Humans; Imidazoles; In Vitro Techniques; Inflammation; Leukocytes; Leukotriene B4; Macrophages; Macrophages, Peritoneal; Mice; Neutrophils; Nitrites; Pancreatic Elastase; Peroxidase; Pyrimidines; Superoxides; Zymosan | 2001 |
Epstein-Barr virus primes human polymorphonuclear leucocytes for the biosynthesis of leukotriene B4.
Topics: Arachidonic Acid; Calcimycin; Calcium Signaling; Enzyme Activation; Epstein-Barr Virus Infections; Herpesvirus 4, Human; Humans; In Vitro Techniques; Ionophores; Leukotriene B4; Mitogen-Activated Protein Kinases; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipases A; Phospholipases A2; Phosphorylation; Virus Replication; Zymosan | 2001 |
Effects of caffeoyl conjugates of isoprenyl-hydroquinone glucoside and quinic acid on leukocyte function.
Topics: Asteraceae; Caffeic Acids; Cells, Cultured; Enzyme Inhibitors; Glucosides; Humans; Isomerism; Leukotriene B4; Molecular Structure; Neutrophils; Pancreatic Elastase; Peroxidase; Phenols; Plant Extracts; Quinic Acid; Superoxides | 2002 |
Effects of wogonin, wogonoside, and 3,5,7,2',6'-pentahydroxyflavone on chemical mediator production in peritoneal exduate cells and immunoglobulin E of rat mesenteric lymph node lymphocytes.
Topics: Animals; Ascitic Fluid; Flavanones; Flavonoids; Glucosides; Histamine; Immunoglobulin E; Leukotriene B4; Lipid Peroxidation; Lipid Peroxides; Lymph Nodes; Lymphocytes; Mesentery; Molecular Structure; Rats; Scutellaria baicalensis | 2003 |
A new dual inhibitor of arachidonate metabolism isolated from Helichrysum italicum.
Topics: Acetophenones; Analgesics; Animals; Arachidonic Acid; Carrageenan; Dose-Response Relationship, Drug; Ear; Edema; Female; Free Radicals; Glucosides; Helichrysum; Hindlimb; Inflammation; Leukotriene B4; Lipid Peroxidation; Mice; Neutrophils; Peroxidase; Phospholipases A; Plant Extracts; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate | 2003 |
Human ALX receptor regulates neutrophil recruitment in transgenic mice: roles in inflammation and host defense.
Topics: 3T3 Cells; Animals; Cell Line; Chromatography, Liquid; Dinoprostone; Female; Humans; Hydroxyeicosatetraenoic Acids; Inflammation; Leukotriene B4; Lipoxins; Male; Mass Spectrometry; Mice; Mice, Transgenic; Neutrophil Infiltration; NF-kappa B; Peritoneum; Peritonitis; Plasmids; Receptors, Cell Surface; Receptors, Formyl Peptide; Receptors, Lipoxin; Skin; Transfection; Tumor Necrosis Factor-alpha; Zymosan | 2003 |
LAAE-14, a new in vitro inhibitor of intracellular calcium mobilization, modulates acute and chronic inflammation.
Topics: Acute Disease; Animals; Arthritis, Experimental; Calcium; Carrageenan; Cell Movement; Chronic Disease; Dinoprostone; Disease Models, Animal; Edema; Humans; Inflammation; Leukotriene B4; Luminescent Measurements; Macrophages, Peritoneal; Mice; Neutrophils; Nitrites; Pancreatic Elastase; Rats; Tumor Necrosis Factor-alpha; Zymosan | 2003 |
Critical role of histamine H4 receptor in leukotriene B4 production and mast cell-dependent neutrophil recruitment induced by zymosan in vivo.
Topics: Animals; Bone Marrow Cells; Carrageenan; Cimetidine; Cytokines; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Histamine Release; Leukotriene B4; Mast Cells; Mice; Mice, Inbred BALB C; Neutrophil Infiltration; Piperidines; Pleurisy; Pyrilamine; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H3; Receptors, Histamine H4; Zymosan | 2003 |
Beneficial effects of heme oxygenase-1 up-regulation in the development of experimental inflammation induced by zymosan.
Topics: Animals; Bilirubin; Blotting, Western; Cell Count; Cell Division; Cytokines; Dinoprostone; Eicosanoids; Exudates and Transudates; Female; Flow Cytometry; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Hemin; Inflammation; Interleukin-1; Leukotriene B4; Macrophages; Membrane Proteins; Mice; Phagocytosis; Tumor Necrosis Factor-alpha; Up-Regulation; Zymosan | 2003 |
Blockade of leukotriene B4 prevents articular incapacitation in rat zymosan-induced arthritis.
Topics: Acetates; Animals; Arthritis, Experimental; Benzeneacetamides; Cell Movement; Cyclopropanes; Exudates and Transudates; Hindlimb; Hydroxamic Acids; Indoles; Joints; Leukotriene Antagonists; Leukotriene B4; Male; Quinolines; Rats; Rats, Wistar; Sulfides; Zymosan | 2004 |
Leukotrienes modulate cytokine release from dendritic cells.
Topics: Animals; Bone Marrow Cells; Cells, Cultured; Cytokines; Dendritic Cells; Interleukin-10; Leukotriene B4; Leukotrienes; Lipopolysaccharides; Mice; Mice, Inbred CBA; Receptors, Leukotriene B4; Receptors, Purinergic P2; Transforming Growth Factor beta; Transforming Growth Factor beta1; Zymosan | 2005 |
Characterization of certain inflammatory variables in the peripheral blood of clinically healthy dogs.
Topics: Animals; Dogs; Female; Leukocytes, Mononuclear; Leukotriene B4; Luminescent Measurements; Male; Neutrophils; Reactive Oxygen Species; Time Factors; Zymosan | 2006 |
Anti-inflammatory and anti-nociceptive activity of risedronate in experimental pain models in rats and mice.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Diphosphonates; Disease Models, Animal; Dose-Response Relationship, Drug; Etidronic Acid; Inflammation; Leukotriene B4; Male; Mice; Pain; Pain Measurement; Rats; Rats, Wistar; Risedronic Acid; Tumor Necrosis Factor-alpha; Zymosan | 2006 |
New insight into the inhibition of the inflammatory response to experimental delayed-type hypersensitivity reactions in mice by scropolioside A.
Topics: Allergens; Animals; Anti-Inflammatory Agents; Apoptosis; Caspase 3; Cell Line; Cytokines; Dinoprostone; Ear; Edema; Erythrocytes; Female; Glucosides; Humans; Hypersensitivity, Delayed; Leukotriene B4; Lipopolysaccharides; Macrophages; Mice; Neutrophils; Oxazolone; Pancreatic Elastase; Pyrans; Sheep; T-Lymphocytes | 2007 |
Mast cell-expressed complement receptor, not TLR2, is the main detector of zymosan in peritonitis.
Topics: Animals; Cell Movement; Complement Activation; Injections, Intraperitoneal; Leukocytosis; Leukotriene B4; Mast Cells; Mice; Mice, Inbred C57BL; Mice, Knockout; Neutrophils; Peritonitis; Receptor, Anaphylatoxin C5a; Receptors, Complement; Toll-Like Receptor 2; Zymosan | 2007 |
Mechanisms underlying the anti-inflammatory activity and gastric safety of acemetacin.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Biotransformation; Chromatography, High Pressure Liquid; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Exudates and Transudates; Indomethacin; Inflammation; Injections, Subcutaneous; Leukotriene B4; Male; Prostaglandins; Rats; Rats, Wistar; Stomach Ulcer; Thromboxanes; Zymosan | 2007 |
Involvement of LTB4 in zymosan-induced joint nociception in mice: participation of neutrophils and PGE2.
Topics: Animals; Arachidonate 5-Lipoxygenase; Benzopyrans; Carboxylic Acids; Cell Movement; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Indoles; Leukotriene B4; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neutrophils; Temporomandibular Joint; Temporomandibular Joint Disorders; Time Factors; Zymosan | 2008 |
Endothelins modulate inflammatory reaction in zymosan-induced arthritis: participation of LTB4, TNF-alpha, and CXCL-1.
Topics: Animals; Antihypertensive Agents; Arthritis; Bosentan; Cell Movement; Chemokine CXCL1; Chemokines; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin Receptor Antagonists; Endothelin-1; Enzyme-Linked Immunosorbent Assay; Immunoblotting; Immunologic Factors; Inflammation Mediators; Knee Joint; Leukocytes; Leukotriene B4; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Neutrophil Infiltration; Neutrophils; Oligopeptides; Peptides, Cyclic; Piperidines; Receptors, Endothelin; Reverse Transcriptase Polymerase Chain Reaction; Sulfonamides; Synovial Fluid; Tumor Necrosis Factor-alpha; Vasoconstrictor Agents; Viper Venoms; Zymosan | 2008 |
Effects of nitric oxide on neutrophil influx depends on the tissue: role of leukotriene B4 and adhesion molecules.
Topics: Acute Disease; Animals; Arthritis; CD18 Antigens; Cell Movement; Intercellular Adhesion Molecule-1; Interleukin-10; Joints; Leukotriene B4; Lipopolysaccharides; Male; Mice; Mice, Knockout; Neutrophil Infiltration; Nitric Oxide; Nitric Oxide Synthase; Peritoneal Cavity; Peritonitis; Rats; Rats, Wistar; Species Specificity; Tumor Necrosis Factor-alpha; Zymosan | 2009 |
Pharmacological characterization of 3-[3-tert-butylsulfanyl-1-[4-(6-methoxy-pyridin-3-yl)-benzyl]-5-(pyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethyl-propionic acid (AM103), a novel selective 5-lipoxygenase-activating protein inhibitor that reduces acute
Topics: 5-Lipoxygenase-Activating Proteins; Acute Disease; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Carrier Proteins; Chronic Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Extravasation of Diagnostic and Therapeutic Materials; Female; Humans; Indoles; Inflammation; Leukotriene B4; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; Pneumonia; Propionates; Rats; Rats, Sprague-Dawley; Zymosan | 2009 |
Pharmacology of AM803, a novel selective five-lipoxygenase-activating protein (FLAP) inhibitor in rodent models of acute inflammation.
Topics: 5-Lipoxygenase-Activating Proteins; Animals; Carrier Proteins; Chronic Disease; Cysteine; Disease Models, Animal; Female; Humans; Indoles; Inflammation; Leukotriene B4; Leukotrienes; Lung; Male; Membrane Proteins; Mice; Pentanoic Acids; Platelet Activating Factor; Propionates; Rats; Substrate Specificity; Zymosan | 2010 |
Mechanisms for anti-inflammatory effects of 1-[15(S)-hydroxyeicosapentaenoyl] lysophosphatidylcholine, administered intraperitoneally, in zymosan A-induced peritonitis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cytokines; Eicosapentaenoic Acid; In Vitro Techniques; Inflammation Mediators; Injections, Intraperitoneal; Leukocytes; Leukotriene B4; Leukotriene C4; Lysophosphatidylcholines; Male; Mice; Mice, Inbred ICR; Oligopeptides; Oxidation-Reduction; Peritonitis; Structure-Activity Relationship; Zymosan | 2011 |
Dietary aloin, aloesin, or aloe-gel exerts anti-inflammatory activity in a rat colitis model.
Topics: Aloe; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chromones; Colitis; Colon; Diet; Dietary Supplements; Disease Models, Animal; Emodin; Gels; Glucosides; Interleukin-1beta; Leukotriene B4; Male; Peroxidase; Plant Preparations; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 2011 |
Anti-arthritic activity of agnuside mediated through the down-regulation of inflammatory mediators and cytokines.
Topics: Adrenalectomy; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Capillary Permeability; Carrageenan; Cell Movement; Cytokines; Dextrans; Edema; Female; Glucosides; Histamine; Leukotriene B4; Lymphocytes; Male; Mice; Rats; Rats, Wistar; Vitex | 2012 |
Self-limited versus delayed resolution of acute inflammation: temporal regulation of pro-resolving mediators and microRNA.
Topics: 3' Untranslated Regions; Acute Disease; Animals; Apoptosis; Arachidonate 5-Lipoxygenase; Cells, Cultured; Dinoprostone; Exudates and Transudates; Gene Expression; Humans; Inflammation; Inflammation Mediators; Leukotriene B4; Lipid Metabolism; Macrophages; Male; Mice; MicroRNAs; Neutrophils; Peritonitis; Prostaglandin D2; RNA Interference; Zymosan | 2012 |
The role of PAF/PAFR signaling in zymosan-induced articular inflammatory hyperalgesia.
Topics: Animals; Dihydropyridines; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperalgesia; Imidazoles; Immune System Diseases; Inflammation; Joint Diseases; Leukocyte Disorders; Leukotriene B4; Male; Mice; Mice, Inbred BALB C; Mice, Knockout; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Prostaglandins; Receptors, G-Protein-Coupled; Time Factors; Zymosan | 2013 |
Tulathromycin exerts proresolving effects in bovine neutrophils by inhibiting phospholipases and altering leukotriene B4, prostaglandin E2, and lipoxin A4 production.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bronchoalveolar Lavage Fluid; Calcimycin; Cattle; Dinoprostone; Disaccharides; Heterocyclic Compounds; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Lipoxins; Lung; Male; Neutrophils; Particulate Matter; Phospholipases A2; Pneumonia; Primary Cell Culture; Zymosan | 2014 |
In vivo sex differences in leukotriene biosynthesis in zymosan-induced peritonitis.
Topics: Animals; Arachidonate 5-Lipoxygenase; Ascitic Fluid; Capillary Permeability; Female; Leukotriene B4; Leukotriene C4; Macrophages, Peritoneal; Male; Mice; Orchiectomy; Peritonitis; Peroxidase; Sex Characteristics; Testosterone; Zymosan | 2014 |
Immunomodulatory effects of tulathromycin on apoptosis, efferocytosis, and proinflammatory leukotriene B4 production in leukocytes from Actinobacillus pleuropneumoniae-or zymosan-challenged pigs.
Topics: Actinobacillus Infections; Actinobacillus pleuropneumoniae; Animals; Anti-Inflammatory Agents; Apoptosis; Disaccharides; Heterocyclic Compounds; Leukocytes; Leukotriene B4; Male; Phagocytosis; Pneumonia, Bacterial; Specific Pathogen-Free Organisms; Swine; Swine Diseases; Zymosan | 2015 |
Protective activity of salidroside against ethanol-induced gastric ulcer via the MAPK/NF-κB pathway in vivo and in vitro.
Topics: Animals; Anti-Ulcer Agents; Arachidonate 5-Lipoxygenase; Cell Line; Cell Survival; Cyclooxygenase 2; Cytokines; Ethanol; Glucosides; Humans; Hydrogen Peroxide; Leukotriene B4; Male; Mice, Inbred BALB C; Mitogen-Activated Protein Kinases; NF-kappa B; Phenols; Signal Transduction; Stomach; Stomach Ulcer | 2015 |
Paracrine in vivo inhibitory effects of adipose tissue-derived mesenchymal stromal cells in the early stages of the acute inflammatory response.
Topics: Adipose Tissue; Animals; Cell Movement; Culture Media, Conditioned; Cyclooxygenase 2; Cytokines; Dinoprostone; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique; Inflammation; Interleukin-1beta; Interleukin-6; Intramolecular Oxidoreductases; Leukocytes; Leukotriene B4; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Paracrine Communication; Prostaglandin-E Synthases; Transcription Factor RelA; Tumor Necrosis Factor-alpha; Zymosan | 2015 |
Neutrophil contributions to the induction and regulation of the acute inflammatory response in teleost fish.
Topics: Acute Disease; Animals; Apoptosis; Goldfish; Immunity, Innate; Kidney; Leukotriene B4; Lipoxins; Macrophage Activation; Macrophages, Peritoneal; Neutrophils; Peritonitis; Phagocytosis; Reactive Oxygen Species; Respiratory Burst; Time Factors; Zymosan | 2016 |
The hallucinogenic diterpene salvinorin A inhibits leukotriene synthesis in experimental models of inflammation.
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Diterpenes; Diterpenes, Clerodane; Hallucinogens; Inflammation; Leukotriene Antagonists; Leukotriene B4; Macrophages, Peritoneal; Mice; Models, Theoretical; Rats; Rats, Wistar; Zymosan | 2016 |
Synthesis and structure-activity relationships of novel 5-(hydroxamic acid)methyl oxazolidinone derivatives as 5-lipoxygenase inhibitors.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Cell Line; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Humans; Hydroxamic Acids; Inflammation; Leukotriene B4; Lipoxygenase Inhibitors; Male; Mice; Mice, Inbred BALB C; Molecular Structure; Oxazolidinones; Structure-Activity Relationship; Zymosan | 2020 |
New isoflavone glucosides in yabumame (Amphicarpaea bracteata (L.) Fernald subsp. edgeworthii (Benth.) H.Ohashi var. japonica (Oliv.) H.Ohashi) and their effect on leukotriene B
Topics: Fabaceae; Glucosides; Isoflavones; Leukotriene B4; Mast Cells | 2021 |
Anti-Inflammatory and Proresolving Effects of the Omega-6 Polyunsaturated Fatty Acid Adrenic Acid.
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arthritis, Experimental; Cells, Cultured; Fatty Acids, Omega-6; Fatty Acids, Unsaturated; Humans; Leukotriene B4; Lipidomics; Macrophages; Male; Mice; Mice, Transgenic; Neutrophils; Peritoneal Lavage; Peritonitis; Primary Cell Culture; THP-1 Cells; Zymosan | 2020 |
NLRP3 as Putative Marker of Ipilimumab-Induced Cardiotoxicity in the Presence of Hyperglycemia in Estrogen-Responsive and Triple-Negative Breast Cancer Cells.
Topics: Antineoplastic Agents, Immunological; Benzhydryl Compounds; Biomarkers, Pharmacological; Cardiotoxicity; Cell Line, Tumor; CTLA-4 Antigen; Female; Glucose; Glucosides; Humans; Hyperglycemia; Ipilimumab; Leukotriene B4; Myeloid Differentiation Factor 88; Myocytes, Cardiac; NLR Family, Pyrin Domain-Containing 3 Protein; Sodium-Glucose Transporter 2 Inhibitors; Transcription Factor RelA; Triple Negative Breast Neoplasms | 2020 |
Spatiotemporal dynamics of calcium signals during neutrophil cluster formation.
Topics: Animals; Calcium; Calcium Signaling; Candida albicans; Leukotriene B4; Mice; Neutrophils; Zymosan | 2022 |
NADPH oxidase 2 limits amplification of IL-1β-G-CSF axis and an immature neutrophil subset in murine lung inflammation.
Topics: Animals; Granulocyte Colony-Stimulating Factor; Granulomatous Disease, Chronic; Inflammation; Interleukin-1beta; Leukotriene B4; Mice; NADPH Oxidase 2; NADPH Oxidases; Neutrophils; Pneumonia; Zymosan | 2023 |