glucose, (beta-d)-isomer has been researched along with arachidonic acid in 216 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 87 (40.28) | 18.7374 |
| 1990's | 82 (37.96) | 18.2507 |
| 2000's | 31 (14.35) | 29.6817 |
| 2010's | 13 (6.02) | 24.3611 |
| 2020's | 3 (1.39) | 2.80 |
| Authors | Studies |
|---|---|
| Dieter, P | 1 |
| Alava, M; Bonvini, E; Hoffman, T; Puri, J; Taplits, M | 1 |
| Daum, T; Rohrbach, MS | 1 |
| Akimaru, K; Klostergaard, J; Sato, EF; Utsumi, K; Utsumi, T; Yoshioka, T | 1 |
| Abe, M; Goya, T; Muranishi, H; Nagata, N; Shigematsu, N; Takahashi, H | 1 |
| Bossaert, L; De Backer, WA; Jorens, PG; Rampart, M; van Overveld, FJ; Vermeire, PA | 1 |
| Arai, H; Kita, T; Nagano, Y; Narumiya, S | 1 |
| Abraham, RT; Kreofsky, T; Rohrbach, MS; Schlager, JW; Vuk-Pavlović, Z | 1 |
| Marshall, TM; Peters-Golden, M; Sporn, PH | 2 |
| Hoffman, T; Pierce, JH; Puri, J | 1 |
| Balsinde, J; Diez, E; Fernández, B; Solís-Herruzo, JA | 1 |
| Bens, M; Coulaud, J; Dardenne, M; Homo-Delarche, F; Lety, MA | 1 |
| Heidel, JR; Laegreid, WW; Leid, RW; Silflow, RM; Taylor, SM | 1 |
| Letari, O; Malgaroli, A; Morgan, DW; Nicosia, S; Welton, AF | 1 |
| Edashige, K; Inoue, M; Matsuno, T; Sato, EF; Takahashi, R; Utsumi, K | 1 |
| Saeki, K; Utsumi, K; Yamamoto, M | 1 |
| Balsinde, J; Fernández, B | 1 |
| Dieter, P; Fitzke, E | 3 |
| Forn, J; García-Rafanell, J; Gómez, LA; Merlos, M; Vericat, L | 1 |
| Angenot, L; Damas, J; Quetin-Leclercq, J; Tits, M | 1 |
| Letari, O; Nicosia, S | 1 |
| Borgeat, P; Odeimat, A; Poubelle, PE | 1 |
| Crivellari, MT; De Rose, V; Folco, GC; Gialdroni Grassi, G; Masciarelli, M; Pozzi, E; Semenzato, G; Trentin, L; Viganò, T | 1 |
| Abrahamsen, TG; Carter, CS; Hoffman, T; Jessop, JJ; Lee, YL; Lizzio, EF; Puri, J; Taplits, M; Tripathi, AK | 1 |
| Mishra, BS; Sandra, A | 1 |
| Foreyt, WJ; Laegreid, WW; Leid, RW; Liggitt, HD; Silflow, RM; Taylor, SM | 1 |
| Dowling, RL; Gans, KR; Kerr, JS; Lundy, SR; Mackin, WM; Stevens, TM | 2 |
| Dieter, P; Krause, H; Schulze-Specking, A | 1 |
| Beraud, M; Combis, JM; Forgue, MF; Pipy, B; Souqual, MC | 1 |
| Balsinde, J; Diez, E; Fernández, B | 1 |
| Dani, GM; Englen, MD; Laegreid, WW; Leid, RW; Liggitt, HD; Silflow, RM; Taylor, SM | 1 |
| Fukuda, T; Masuzawa, Y; Sugiura, T; Waku, K | 1 |
| Lim, WH; Stewart, AG | 1 |
| Brieland, JK; Fantone, JC; McNish, RW; Peters-Golden, M | 1 |
| Banks, KL; Englen, MD; Laegreid, WW; Silflow, RM; Taylor, SM; Wes Leid, R | 1 |
| DuBourdieu, DJ; Morgan, DW | 1 |
| Brown, TT; Fleisher, LN; MacLachlan, NJ; O'Sullivan, MG; Olson, NC | 1 |
| Britigan, BE; Hamill, DR | 1 |
| Aderem, AA; Cohn, ZA; Scott, WA | 1 |
| Bartalini, M; Boraschi, D; Censini, S; Di Simplicio, P; Ghiara, P; Tagliabue, A | 1 |
| Gennaro, DE; Godfrey, RW; Hoffstein, ST; Manzi, RM | 1 |
| Sundler, R; Wijkander, J | 1 |
| Hellewell, PG; Williams, TJ; Yarwood, H | 1 |
| Diez, E; Fernandez, B; Martin, C; Schuller, A; Zamorano, P | 1 |
| Englen, MD; Laegreid, WW; Leid, RW; Liggitt, HD; Silflow, RM; Straub, KM; Taylor, SM | 1 |
| Dowling, RL; Gans, KR; Kerr, JS; Lundy, SR; Stevens, TM | 1 |
| Balter, MS; Peters-Golden, M; Toews, GB | 2 |
| Benveniste, J; Dulioust, A; Haye-Legrand, I; Meslier, N; Roubin, R; Vivier, E | 1 |
| Breeze, RG; Evermann, JR; Laegreid, WW; Leid, RW; Liggitt, HD; Silflow, RM; Taylor, SM | 1 |
| Brom, J; Erbs, G; Köller, M; König, W; Müller, FE | 1 |
| Burgess, JR; Eskew, ML; Hildenbrandt, G; Reddy, CC; Scheuchenzuber, WJ; Scholz, RW; Zarkower, A | 1 |
| Maki, Y; Makino, H; Saijo, T | 1 |
| Edenius, C; Lindgren, JA; Sjöquist, B; Smedegård, G; Tornhamre, S | 1 |
| Giedd, KN; Haines, KA; Korchak, HM; Reibman, J; Rich, AM; Weissmann, G | 1 |
| Decker, K; Dieter, P; Schulze-Specking, A | 1 |
| Bar-Shavit, Z; Stenson, WF; Teitelbaum, SL | 1 |
| Berton, G; Valletta, EA | 1 |
| Hollenberg, MD; Johnson, LK; Northup, JK; Severson, DL; Valentine-Braun, KA | 1 |
| Austen, F; Lee, TH; Lewis, RA; Williams, JD | 1 |
| Altom, MG; Nanda, SK; Schultz, RM | 1 |
| Bonney, RJ; Humes, JL; Opas, EE | 1 |
| Aracil, M; Balsinde, J; Diez, E; Garcia Barreno, P; Moscat, J; Municio, AM | 1 |
| Beraud, M; de Maroussem, D; Forgue, MF; Pipy, B; Souqual, MC | 1 |
| Bell, RM; Lambeth, JD; Merrill, AH; Olcott, MC; Wilson, E | 1 |
| Bell, AL; Betts, WH; Cleland, LG; French, JK; Hurst, NP; Nuki, G; O'Donnell, ML | 1 |
| Adams, DO; Lewis, JG | 1 |
| Maridonneau-Parini, I; Tauber, AI; Tringale, SM | 1 |
| Roth, JA; Webb, DS | 1 |
| Giedd, KN; Haines, KA; Korchak, HM; Rich, AM; Weissmann, G | 1 |
| Peters-Golden, M; Thebert, P | 1 |
| Czop, JK | 1 |
| Ferber, E; Mossmann, H; Phillips, WA | 1 |
| Bonney, RJ; Galavage, M; Humes, JL; Opas, EE; Soderman, D | 1 |
| Falck, P; Gruner, S; Volk, HD; Von Baehr, R | 1 |
| Ardaillou, R; Baud, L; Perez, J | 1 |
| Emilsson, A; Sundler, R | 1 |
| Kurihara, K; Nakagawa, Y; Sugiura, T; Waku, K | 1 |
| Hammer, CH; Imagawa, DK; Koga, PG; Mayer, MM; Osifchin, NE; Ramm, LE; Shin, HS | 1 |
| Cook, JA; Halushka, PV; Rogers, TS; Wise, WC | 1 |
| Arichi, S; Kimura, Y; Okuda, H; Okuda, T | 1 |
| Lands, WE; Marshall, PJ | 1 |
| Detty, DM; Leslie, CC | 1 |
| Altin, JG; Bygrave, FL; Dieter, P | 1 |
| Altin, JG; Bygrave, FL; Decker, K; Dieter, P | 1 |
| Arichi, S; Kimura, Y; Nishibe, S; Okuda, H | 1 |
| Peters-Golden, M; Shelly, C | 1 |
| Bruijnzeel, PL; Hamelink, ML; Kijne, AM; Kok, PT; Verhagen, J | 1 |
| Calhoun, W; Carlson, RP; Chang, J | 1 |
| Peters-Golden, M; Simon, RH; Sporn, PH | 1 |
| Burch, RM | 1 |
| Chapkin, RS; Erickson, KL; Somers, SD | 1 |
| Gliemann, J; Okuno, Y | 1 |
| Nakagawa, Y; Waku, K | 1 |
| Glaser, KB; Jacobs, RS; Mayer, AM | 1 |
| Beraud, M; de Maroussem, D; Derache, P; Mathieu, JR; Pipy, B | 1 |
| Kinsella, JE; Lokesh, BR | 1 |
| Chang, J; Kreft, AF; Lamb, B; Lewis, AJ; Marinari, L | 1 |
| Flynn, JT; Gee, MH; Perkowski, SZ; Tahamont, MV | 1 |
| Chensue, SW; Kunkel, SL | 1 |
| Mahoney, M; Needleman, P; Tripp, CS | 1 |
| Bartalini, M; Boraschi, D; Censini, S; Tagliabue, A | 1 |
| Leahy, KM; Needleman, P; Tripp, CS | 1 |
| Shibata, Y; Tanaka, M | 1 |
| Chensue, SW; Ellul, DA; Higashi, GI; Kunkel, SL; Spengler, M | 1 |
| Fan, TP; Lewis, GP | 1 |
| Busse, WW; Hempel, S; Yocum, DE | 1 |
| Cohn, ZA; Hamill, AL; Rouzer, CA; Scott, WA | 1 |
| Alonso, F; Alvarez Chiva, V; García Gil, M; Mato, JM; Sánchez Crespo, M | 1 |
| Chang, J; Liu, MC; Newcombe, DS | 1 |
| Bonney, RJ; Humes, JL | 1 |
| Austen, KF; Czop, JK; Williams, JD | 1 |
| Chilton, FH; Dechatelet, LR; Waite, M; Walsh, CE; Wykle, RL | 1 |
| Cohn, ZA; Hamill, AL; Kaplan, G; Pawlowski, NA; Scott, WA | 1 |
| Alemany, S; Gil, MG; Mato, JM; Municio, AM; van Lookeren Campagne, MW | 1 |
| Baud, L; Hagege, J; Perez, J; Satriano, JA; Schlondorff, D | 1 |
| Du, JT; Ramey, E; Ramwell, PW; Vennos, E | 1 |
| Chilton, FH; Ellis, JM; Olson, SC; Wykle, RL | 1 |
| Pickering, RJ; Rediske, JJ | 1 |
| Bathon, J; Flores, R; Hirata, F; Newcombe, DS; Peters-Golden, M | 1 |
| Andreach, M; Cohn, ZA; Murray, HW; Pawlowski, NA; Scott, WA; Zrike, J | 1 |
| Cohn, ZA; Griffith, OW; Hamill, AL; Rouzer, CA; Scott, WA | 1 |
| Baggiolini, M; Bretz, U; Dewald, B; Payne, TG; Schnyder, J | 1 |
| Chang, J; Grundfest, CC; Newcombe, D | 1 |
| Bonney, RJ; Dahlgren, ME; Davies, P; Humes, JL; Wightman, PD | 1 |
| Clark, JD; Doerfler, ME; Elsbach, P; Weiss, J | 1 |
| Ambs, P; Baccarini, M; Dieter, P; Fitzke, E | 1 |
| Ferin, MA; Kennedy, JA; Kuipers, PJ; Wright, CD | 1 |
| Ambs, P; Dieter, P; Fitzke, E | 1 |
| Kurata, M; Kuwae, T; Miura, Y; Nakajima, T | 1 |
| Gross, RW; Rudolph, AE; Sommers, CD; Wang, J; Wolf, MJ | 1 |
| Lloret, S; Moreno, JJ | 2 |
| Jackowski, S; Leslie, CC; Qiu, ZH; Rock, CO; Xu, XX | 1 |
| Leslie, CC; Qiu, ZH | 1 |
| Sundler, R; Wijkander, J; Winstedt, D | 1 |
| Hazeki, K; Mori, Y; Tamoto, K; Ui, M | 1 |
| Borgeat, P; Marleau, S; Odeimat, A; Palmantier, R; Poubelle, PE; Surette, ME | 1 |
| Balsinde, J; Fernández, B; Solís-Herruzo, JA | 2 |
| Fruchtmann, R; Fugmann, B; Hatzelmann, A; Horstmann, H; Junge, B; Mohrs, KH; Müller-Peddinghaus, R; Raddatz, S | 1 |
| Huwiler, A; Pfeilschifter, J | 1 |
| de Carvalho, MS; Leslie, CC; Qiu, ZH | 1 |
| Koh, CL; Nagaratnam, M; Pang, T; Puthucheary, S; Yusof, WN | 1 |
| Dana, R; Levy, R; Malech, HL | 1 |
| Goracci, G; Gresele, P; Mezzasoma, AM; Nenci, GG; Prosdocimi, M; Quero, E; Ribaldi, E; Stasi, M | 1 |
| Azzari, C; Baldi, E; Carloni, V; Gentilini, P; Gresele, P; Laffi, G; Marra, F; Rossi, ME | 1 |
| Imai, Y; Kudo, I; Nakagawa, Y; Naraba, H; Oh-ishi, S | 1 |
| Tool, AT; Verhoeven, AJ | 1 |
| Aderem, A; Rosen, A; Veis, N | 1 |
| Lloret, S; Mitjavila, MT; Moreno, JJ; Rodríguez, MC; Sáiz, MP | 1 |
| Matsumoto, H; Naraba, H; Oh-ishi, S; Ueno, A | 1 |
| Derksen, FJ; Hostetler, DE; Lu, MC; Peters-Golden, M; Robinson, NE | 1 |
| Calder, PC; Mirzoeva, OK | 1 |
| Byrum, RS; Goulet, JL; Griffiths, RJ; Koller, BH | 1 |
| Carty, TJ; Cheng, JD; Ernest, MJ; Eskra, JD; Griffiths, RJ; Joseph, PA; Kadin, SB; Loose, LD; Moore, PF; Murase, S; Nagahisa, A; Pazoles, PP; Pillar, JS; Sweeney, FJ | 1 |
| Dikshit, M; Kumari, R; Seth, P | 1 |
| Oh-ishi, S | 1 |
| Ambs, P; Baccarini, M; Dieter, P; Fitzke, E; Schwende, H | 1 |
| de Carvalho, MS; Gijón, MA; Leslie, CC; Qiu, ZH; Spencer, DM | 1 |
| Birdwell, C; Li, B; Whelan, J | 1 |
| Fiedler, J; Henson, PM; Murphy, RC; Wheelan, P | 1 |
| Akiba, S; Hayama, M; Kume, K; Mizunaga, S; Sato, T | 1 |
| Caput, D; Escoubet, L; Ferrara, P; Pipy, B; Quartulli, F; Rey, A; Sozzani, P | 1 |
| Byrum, RS; Goulet, JL; Key, ML; Koller, BH; Nguyen, M; Wagoner, VA | 1 |
| Hiller, G; Sternby, M; Sundler, R; Wijkander, J | 1 |
| Bonventre, JV; Gijón, MA; Leslie, CC; Siddiqi, AR; Spencer, DM | 1 |
| Caughey, GE; Cleland, LG; Demasi, M; James, MJ; Penglis, PS | 1 |
| Bock, CB; Haribabu, B; Sellars, DD; Snyderman, R; Steeber, DA; Verghese, MW | 1 |
| Duan, H; Yan, W; Yang, X; Ye, J; Zheng, X | 1 |
| Borgeat, P; Flamand, L; Gosselin, J; Savard, M; Tardif, M | 1 |
| Akiba, S; Chiba, M; Hayama, M; Kume, K; Ohno, S; Sato, T | 1 |
| Giner, RM; Máñez, S; Recio, MC; Ríos, JL; Sala, A; Schinella, GR | 1 |
| Han, L; Zhang, J; Zheng, Y | 1 |
| Gábor, M | 1 |
| Kimura, Y | 1 |
| Alonso, S; Crespo, MS; Fernández, N; Renedo, M | 1 |
| Jin, JL; Lee, S; Lee, YY; Yun-Choi, HS | 1 |
| Burke, D; Evans, JH; Girotti, M; Leslie, CC | 1 |
| Davletov, B; Rickman, C | 1 |
| Feng, J; Gryczynski, Z; Kobayashi, M; Lakowicz, JR; Lomasney, JW; Lukomska, J; Roberts, MF | 1 |
| Beck-Speier, I; Dayal, N; Karg, E; Koelsch, SM; Maier, KL; Schumann, G; Semmler, M | 1 |
| Darlath, W; Gillissen, A; Juergens, UR; Racké, K; Stober, M; Tasci, S; Vetter, H | 1 |
| Han, LK; Kimura, Y; Okuda, H; Sekiya, K; Zhang, J; Zheng, YN | 1 |
| Akira, S; Brown, GD; Ghosh, M; Gordon, S; Leslie, CC; Loper, R; Suram, S; Taylor, PR; Uematsu, S; Williams, DL | 1 |
| Jeong, CH; Kang, HS; Kim, CJ; Lee, JH; Lee, JY; Moon, H; Sim, SS; Whang, WK | 1 |
| Cai, X; Chen, DM; Xiao, L; Zeng, R; Zhu, XZ | 1 |
| Olsson, S; Sundler, R | 1 |
| Choi, WS; Ha, CG; Her, E; Jun, SH; Kim, BK; Kim, NW; Kim, YM; Ko, NY; Lee, JH; Lee, JM; Lee, MH; Lee, SH; Mun, SH; Park, SH | 1 |
| Cho, SW; Hahm, KB; Han, SU; Lee, KM; Park, KH; Park, S | 1 |
| Hansen, AJ; Jensen, LD; Lundbaek, JA | 1 |
| Diskin, R; Engelberg, D; Livnah, O | 1 |
| Farber, HW; Gaposchkin, DP; Zoeller, RA | 1 |
| Alonso, A; Alonso, S; Brown, GD; Crespo, MS; Fernández, N; Trinidad, AG; Valera, I | 1 |
| Gelb, MH; Gijón, MA; Leslie, CC; Qiu, ZH; Spencer, DM; Tucker, DE | 1 |
| Alonso, S; Alvarez, Y; Fernández, N; Municio, C; San Román, JA; Sánchez Crespo, M | 1 |
| Astudillo, AM; Balboa, MA; Balsinde, J; Pérez-Chacón, G; Ruipérez, V | 1 |
| Bramanti, P; Cuzzocrea, S; Dehm, F; Hoffmann, M; Koeberle, A; Pergola, C; Rossi, A; Sautebin, L; Werz, O | 1 |
| Broughton, KS; Handrich, E; Rule, DC | 1 |
| Bristot, L; Campo, G; Ferrari, R; Gambetti, S; Marchesini, J; Monti, M; Pavasini, R; Pollina, A | 1 |
| Astudillo, AM; Balboa, MA; Balsinde, J; Gil-de-Gómez, L; Guijas, C; Rubio, JM | 1 |
| Alonso, S; Alvarez, Y; Crespo, MS; Domingo, E; Fernández, N; Hugo, E; Montero, O; Municio, C; Rodríguez, M | 1 |
| Astudillo, AM; Balboa, MA; Balsinde, J; Gil-de-Gómez, L; Guijas, C; Kokotos, G; Magrioti, V | 1 |
| Jo, YS; Ko, MS; Sim, SS; Song, HS; Whang, WK | 1 |
| Brown, HA; Hermanson, DJ; Lindsley, CW; Lopez, CF; Marnett, LJ; Mitchener, MM; Reese, J; Rouzer, CA; Shockley, EM | 1 |
| Capasso, R; Guerra, G; Izzo, AA; Pace, S; Pagano, E; Rossi, A; Roviezzo, F; Tedesco, F; Troisi, F; Werner, M; Werz, O; Zjawiony, JK | 1 |
| Fu, H; Fu, J; Lu, H; Luo, Y; Ma, S; Wang, W; Xu, H; Zhang, Z; Zhu, X | 1 |
| Chen, H; Feng, N; Liu, X; Liu, Y; Qiu, M; Tang, H; Wang, C; Yang, J; Zhang, J; Zhou, X | 1 |
| Astudillo, AM; Balboa, MA; Balsinde, J; Fernández-Caballero, L; Kokotos, G; Lebrero, P; Rubio, JM | 1 |
| Auger, JL; Binstadt, B; Brouwers, H; Clària, J; Freysdottir, J; Garrido-Mesa, J; Giera, M; Gonzalez-Torres, M; Hardardottir, I; Huizinga, TWJ; Ioan-Facsinay, A; Jónasdóttir, HS; Kloppenburg, M; Kuipers, ME; Kwekkeboom, JC; López-Vicario, C; Norling, LV; Perretti, M; Toes, REM | 1 |
| Greenberg, AS; Han, X; Pan, M; Reeves, AR; Sansbury, BE; Spite, M | 1 |
| Balboa, MA; Balsinde, J; Bermúdez, MA; Rubio, JM | 1 |
4 review(s) available for glucose, (beta-d)-isomer and arachidonic acid
| Article | Year |
|---|---|
Lipoxygenase pathways of macrophages.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Leukotrienes; Lipid Peroxides; Lipoxygenase; Lymphocyte Activation; Macrophages; Mice; Prostaglandin-Endoperoxide Synthases; Rats; SRS-A; T-Lymphocytes; Zymosan | 1985 |
[Analysis of chemical mediators involved in acute inflammatory reaction with the rat pleurisy model].
Topics: Animals; Arachidonic Acid; Capillary Permeability; Carrageenan; Cell Movement; Chemokines; Complement System Proteins; Disease Models, Animal; Eicosanoids; Histamine; Inflammation; Kallikrein-Kinin System; Male; Neutrophils; Platelet Activating Factor; Pleurisy; Rats; Zymosan | 1997 |
Models of acute inflammation in the ear.
Topics: Alkynes; Animals; Anthralin; Arachidonic Acid; Cantharidin; Capsaicin; Carrageenan; Croton Oil; Dermatitis; Disease Models, Animal; Diterpenes; Edema; Foot; Inflammation; Irritants; Male; Mice; Models, Animal; Mustard Plant; Otitis Externa; Plant Extracts; Plant Oils; Rats; Reproducibility of Results; Terpenes; Tetradecanoylphorbol Acetate; Zymosan | 2003 |
Pharmacological studies on resveratrol.
Topics: Animals; Antineoplastic Agents; Apoptosis; Arachidonic Acid; Cell Degranulation; Chemical and Drug Induced Liver Injury; Glucosides; Humans; Hyperlipidemias; Hypolipidemic Agents; Lipid Peroxidation; Neoplasm Metastasis; Neutrophils; Phytotherapy; Polygonum; Resveratrol; Stilbenes | 2003 |
1 trial(s) available for glucose, (beta-d)-isomer and arachidonic acid
| Article | Year |
|---|---|
The in vitro effects of verbascoside on human platelet aggregation.
Topics: Adenosine Diphosphate; Adult; Aged; Animals; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Blood Platelets; Coronary Disease; Female; Glucosides; Humans; Male; Middle Aged; Phenols; Platelet Aggregation | 2012 |
211 other study(ies) available for glucose, (beta-d)-isomer and arachidonic acid
| Article | Year |
|---|---|
Relationship between intracellular pH changes, activation of protein kinase C and NADPH oxidase in macrophages.
Topics: Animals; Arachidonic Acid; Carrier Proteins; Cells, Cultured; Cytoplasm; Enzyme Activation; Fluorides; Hydrogen-Ion Concentration; Interphase; Ionomycin; Liver; Macrophages; NADH, NADPH Oxidoreductases; NADPH Oxidases; Phorbol Esters; Protein Kinase C; Sodium-Hydrogen Exchangers; Zymosan | 1992 |
Inhibition of release of arachidonic acid, superoxide, and IL-1 from human monocytes by monoclonal anti-HLA class II antibodies: effects at proximal and distal points of inositol phospholipid hydrolysis pathway.
Topics: Antibodies, Monoclonal; Arachidonic Acid; Calcium; Cyclic AMP; Histocompatibility Antigens Class II; Humans; Hydrolysis; In Vitro Techniques; Interleukin-1; Ionomycin; Monocytes; Phosphatidylinositols; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1992 |
Zymosan induces selective release of arachidonic acid from rabbit alveolar macrophages via stimulation of a beta-glucan receptor.
Topics: Animals; Arachidonic Acid; Calcimycin; Dose-Response Relationship, Drug; Glucans; Macrophages, Alveolar; Rabbits; Receptors, Cell Surface; Receptors, Immunologic; Zymosan | 1992 |
Effect of tumor necrosis factor-alpha on the stimulus-coupled responses of neutrophils and their modulation by various inhibitors.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Arachidonic Acid; Calcium; Dose-Response Relationship, Drug; Genistein; Humans; In Vitro Techniques; Isoflavones; Isoquinolines; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Piperazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Recombinant Proteins; Superoxides; Tetradecanoylphorbol Acetate; Time Factors; Tumor Necrosis Factor-alpha; Zymosan | 1992 |
Time-dependent alterations of leukotriene production and catabolism in rat peritoneal macrophages following intraperitoneal injection of thioglycollate broth.
Topics: Animals; Arachidonic Acid; Calcimycin; Cell Count; gamma-Glutamyltransferase; Leukotriene B4; Macrophage Activation; Macrophages; Male; Membrane Lipids; Peritonitis; Rats; Rats, Inbred Strains; SRS-A; Thioglycolates; Time Factors; Zymosan | 1992 |
Release of arachidonic acid metabolites from isolated human alveolar type II cells.
Topics: Arachidonic Acid; Calcimycin; Cell Separation; Cells, Cultured; Humans; Hydrogen Peroxide; In Vitro Techniques; Pulmonary Alveoli; Zymosan | 1992 |
Decreased arachidonate metabolism in mouse peritoneal macrophages after foam cell transformation with oxidized low-density lipoproteins.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Cells, Cultured; Chromatography, High Pressure Liquid; Dinoprostone; Fatty Acids; Female; Foam Cells; Lipid Metabolism; Lipids; Lipoproteins, LDL; Macrophage Activation; Macrophages; Mice; Mice, Inbred Strains; Oxidation-Reduction; Peritoneal Cavity; Phospholipases; Phospholipids; SRS-A; Stimulation, Chemical; Zymosan | 1992 |
Condensed tannin promotes the release of arachidonic acid from rabbit resident alveolar macrophages.
Topics: Animals; Arachidonic Acid; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Eicosanoids; Macrophages, Alveolar; Phosphatidylcholines; Phosphatidylinositols; Rabbits; Radioimmunoassay; Tannins; Zymosan | 1992 |
Hydrogen peroxide increases the availability of arachidonic acid for oxidative metabolism by inhibiting acylation into phospholipids in the alveolar macrophage.
Topics: Acylation; Adenosine Triphosphate; Animals; Arachidonic Acid; Calcimycin; Cells, Cultured; Female; Hydrogen Peroxide; Kinetics; Macrophages; Oxidation-Reduction; Phospholipases A; Phospholipases A2; Phospholipids; Pulmonary Alveoli; Rats; Rats, Inbred Strains; Zymosan | 1992 |
Transduction of a signal for arachidonic acid metabolism by untriggered CSF-1 receptor induces an opposite effect to that induced by CSF-1 receptor and its ligand: separate regulation of phospholipase A2 and cyclooxygenase by CSF-1 receptor/CSF-1.
Topics: Animals; Annexins; Arachidonic Acid; Calcium-Binding Proteins; Cinnamates; Dinoprostone; Hematopoietic Stem Cells; Ionomycin; Macrophage Colony-Stimulating Factor; Membrane Lipids; Mice; Phospholipases A; Phospholipases A2; Phosphorylation; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Receptor, Macrophage Colony-Stimulating Factor; Recombinant Proteins; Signal Transduction; Sulfides; Tetradecanoylphorbol Acetate; Zymosan | 1992 |
Pathways for arachidonic acid mobilization in zymosan-stimulated mouse peritoneal macrophages.
Topics: Acyltransferases; Animals; Arachidonic Acid; Cells, Cultured; Cyclohexanones; Dose-Response Relationship, Drug; Enzyme Activation; Lipoprotein Lipase; Macrophage Activation; Macrophages; Masoprocol; Mice; Peritoneum; Phospholipases A; Phospholipases A2; Serum Albumin, Bovine; Zymosan | 1992 |
Enhanced metabolism of arachidonic acid by macrophages from nonobese diabetic (NOD) mice.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Culture Media; Female; Leukotrienes; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Peritoneal Cavity; Zymosan | 1992 |
Characterization of arachidonic acid metabolism, superoxide production, and bacterial killing by bovine alveolar neutrophils elicited with leukotriene B4 and zymosan-activated plasma.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Bacteriolysis; Calcimycin; Cattle; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Male; Neutrophils; Pulmonary Alveoli; Superoxides; Zymosan | 1991 |
Cytosolic calcium ion and arachidonic acid release and metabolism in macrophages.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium; Cytosol; Eicosanoic Acids; Epoprostenol; Fura-2; In Vitro Techniques; L-Lactate Dehydrogenase; Leukotriene B4; Lipopolysaccharides; Macrophages; Male; Microchemistry; Phagocytosis; Phospholipases A; Rats; Rats, Inbred Strains; Spectrometry, Fluorescence; Zymosan | 1991 |
Luminol chemiluminescence and active oxygen generation by activated neutrophils.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Azides; Cytochalasin B; Ferric Compounds; Free Radical Scavengers; Guinea Pigs; Hydroxides; Hydroxyl Radical; Luminescent Measurements; Luminol; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Opsonin Proteins; Oxygen; Peroxidase; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate; Uric Acid; Zymosan | 1991 |
Isolation of human salivary polymorphonuclear leukocytes and their stimulation-coupled responses.
Topics: Annexins; Arachidonic Acid; Arachidonic Acids; Azides; Calcium; Calcium-Binding Proteins; Cell Membrane; Cell Separation; Humans; Kinetics; Luminescent Measurements; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Opsonin Proteins; Peroxidase; Saliva; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1991 |
Receptor-mediated activation of arachidonic acid release in mouse peritoneal macrophages is linked to extracellular calcium influx.
Topics: Animals; Arachidonic Acid; Calcium; Cells, Cultured; Egtazic Acid; Kinetics; Macrophages; Mice; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Receptors, Cell Surface; Verapamil; Zymosan | 1991 |
Effect of long-chain alkylamines on arachidonate metabolism in macrophages.
Topics: Amines; Amino Alcohols; Animals; Arachidonic Acid; Cells, Cultured; Dose-Response Relationship, Drug; Humans; Inositol Phosphates; Liver; Macrophages; Phospholipases A; Prostaglandins; Superoxides; Swine; Zymosan | 1991 |
Comparative study of the effect of CV-6209, a specific PAF-antagonist, on rat paw edema caused by different phlogogen agents.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arachidonic Acids; Carrageenan; Dextrans; Edema; Histamine Antagonists; Male; p-Methoxy-N-methylphenethylamine; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Inbred Strains; Serotonin Antagonists; Zymosan | 1990 |
From ethnobotanical uses of Strychnos henningsii to antiinflammatories, analgesics and antispasmodics.
Topics: Alkaloids; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Carrageenan; Edema; Female; Guinea Pigs; Indoles; Lethal Dose 50; Male; Medicine, African Traditional; Parasympatholytics; Plant Extracts; Plants, Medicinal; Rats; Rats, Inbred Strains; Zymosan | 1991 |
Arachidonic acid release in rat peritoneal macrophages: role of calcium ions.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium; Cytosol; Macrophage Activation; Macrophages; Male; Membrane Lipids; Peritoneal Cavity; Rats; Signal Transduction; Zymosan | 1991 |
Reverse phase HPLC profiling of arachidonic acid metabolites in blood stimulated ex vivo.
Topics: Anticoagulants; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Arachidonic Acids; Aspirin; Calcimycin; Chromatography, High Pressure Liquid; Eicosanoids; Enzyme Activation; Humans; Prostaglandin-Endoperoxide Synthases; Prostaglandins B; Zymosan | 1991 |
Metabolism of arachidonic acid in human alveolar macrophages from patients with sarcoidosis.
Topics: Adult; Arachidonic Acid; Arachidonic Acids; Bronchoalveolar Lavage Fluid; Cells, Cultured; Dinoprostone; Humans; Leukotriene B4; Macrophage Activation; Macrophages; Middle Aged; Phagocytosis; Pulmonary Alveoli; Sarcoidosis; Zymosan | 1991 |
Absence of modulation of monokine production via endogenous cyclooxygenase or 5-lipoxygenase metabolites: MK-886 (3-[1-(4-chlorobenzyl)-3-t-butyl-thio-5-isopropylindol-2-yl]-2,2- dimethylpropanoic acid), indomethacin, or arachidonate fail to alter immunor
Topics: Analysis of Variance; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Arachidonic Acids; Concanavalin A; Dinoprostone; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Humans; In Vitro Techniques; Indoles; Indomethacin; Interleukin-1; Leukotriene Antagonists; Lipopolysaccharides; Monocytes; Prostaglandin-Endoperoxide Synthases; Radioimmunoassay; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Zymosan | 1991 |
Ultrastructural localization of arachidonic acid in stimulated macrophages.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Autoradiography; Calcimycin; Cell Compartmentation; Immunohistochemistry; In Vitro Techniques; Macrophage Activation; Macrophages; Mice; Microscopy, Electron; Zymosan | 1991 |
Comparison of arachidonate metabolism by alveolar macrophages from bighorn and domestic sheep.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Cells, Cultured; Disease Susceptibility; Female; Genetic Predisposition to Disease; Lipoxygenase; Macrophages; Male; Prostaglandin-Endoperoxide Synthases; Pulmonary Alveoli; Respiratory Tract Infections; Sheep; Species Specificity; Tetradecanoylphorbol Acetate; Zymosan | 1991 |
Kinetics of phospholipase A2, arachidonic acid, and eicosanoid appearance in mouse zymosan peritonitis.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Ascitic Fluid; Chromatography, High Pressure Liquid; Eicosanoids; Exudates and Transudates; Gas Chromatography-Mass Spectrometry; Male; Mice; Mice, Inbred Strains; Peritonitis; Phospholipases; Phospholipases A; Phospholipases A2; Radioimmunoassay; Time Factors; Zymosan | 1990 |
Arachidonate metabolism in macrophages is affected by albumin.
Topics: Albumins; Animals; Arachidonic Acid; Arachidonic Acids; Cattle; Culture Media; Eicosanoids; Fluorides; Ionophores; Kupffer Cells; Macrophages; Male; Membrane Lipids; Phorbol Esters; Phospholipids; Rats; Rats, Inbred Strains; Tritium; Zymosan | 1990 |
1-naphthyl N-methyl carbamate effect on intra- and extracellular concentrations of arachidonic acid metabolites, and on the chemiluminescence generation by mouse peritoneal macrophages.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Carbaryl; Cell Survival; Extracellular Space; Intracellular Fluid; Luminescent Measurements; Macrophages; Male; Mice; Oxidation-Reduction; Peritoneal Cavity; Tetradecanoylphorbol Acetate; Time Factors; Tritium; Zymosan | 1990 |
Regulation of arachidonic acid release in mouse peritoneal macrophages. The role of extracellular calcium and protein kinase C.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Ascitic Fluid; Calcimycin; Calcium; Concanavalin A; Inositol Phosphates; Macrophages; Mice; Protein Kinase C; Secretory Rate; Tetradecanoylphorbol Acetate; Zymosan | 1990 |
Influence of extracellular calcium on the metabolism of arachidonic acid in alveolar macrophages.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium; Cattle; Egtazic Acid; Indomethacin; Macrophages; Phospholipases A; Phospholipases A2; Pulmonary Alveoli; Tetradecanoylphorbol Acetate; Zymosan | 1990 |
Extracellular phospholipase A2 activity in two in vivo models of inflammation.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Ascitic Fluid; Calcium; Caseins; Disease Models, Animal; Extracellular Space; Hydrogen-Ion Concentration; Kinetics; Male; Mice; Peritoneal Lavage; Peritonitis; Phospholipases A; Phospholipases A2; Rats; Rats, Inbred Lew; Zymosan | 1990 |
Differential dependence on protein kinase C of arachidonic acid metabolism stimulated by hydrogen peroxide and by zymosan in the alveolar macrophage.
Topics: Alkaloids; Animals; Arachidonic Acid; Arachidonic Acids; Eicosanoids; Female; Hydrogen Peroxide; Macrophages; Phorbol Esters; Protein Kinase C; Pulmonary Alveoli; Rats; Rats, Inbred Strains; Staurosporine; Tetradecanoylphorbol Acetate; Zymosan | 1990 |
Ether lysophospholipid-induced production of platelet-activating factor in human polymorphonuclear leukocytes.
Topics: Acetates; Acetyl Coenzyme A; Arachidonic Acid; Arachidonic Acids; Calcimycin; Humans; In Vitro Techniques; Kinetics; Neutrophils; Platelet Activating Factor; Zymosan | 1990 |
Macrophage activation reduces mobilization of arachidonic acid by guinea-pig and rat peritoneal macrophages in vitro.
Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Arachidonic Acids; Calcimycin; Epoprostenol; Guinea Pigs; Macrophage Activation; Macrophages; Male; N-Formylmethionine Leucyl-Phenylalanine; Peritoneal Cavity; Platelet Activating Factor; Rats; Rats, Inbred Strains; Zymosan | 1990 |
Diminished protein kinase C-activated arachidonate metabolism accompanies rat macrophage differentiation in the lung.
Topics: Alkaloids; Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Cell Differentiation; Dinoprostone; Eicosanoids; Enzyme Activation; Female; Macrophages; Peritoneal Cavity; Phorbol Esters; Protein Kinase C; Pulmonary Alveoli; Rats; Rats, Inbred Strains; Sphingosine; Staurosporine; Superoxides; Zymosan | 1990 |
Production of arachidonic acid metabolites by caprine alveolar macrophages.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Bronchoalveolar Lavage Fluid; Calcimycin; Fatty Acids, Unsaturated; Goats; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Lipid Metabolism; Macrophages; Zymosan | 1990 |
Multiple pathways for signal transduction in the regulation of arachidonic acid metabolism in rat peritoneal macrophages.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cholera Toxin; Colforsin; Cyclic AMP; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Immunoglobulin G; Inflammation; Macrophages; Male; Peritoneal Cavity; Pertussis Toxin; Rats; Rats, Inbred Strains; Signal Transduction; Virulence Factors, Bordetella; Zymosan | 1990 |
Modulation of arachidonic acid metabolism by bovine alveolar macrophages exposed to interferons and lipopolysaccharide.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Cattle; Dinoprost; Interferon Type I; Leukotriene B4; Lipopolysaccharides; Macrophages; Recombinant Proteins; Thromboxane B2; Zymosan | 1990 |
Effect of the spin trap 5,5 dimethyl-1-pyrroline-N-oxide (DMPO) on human neutrophil function: novel inhibition of neutrophil stimulus-response coupling?
Topics: Arachidonic Acid; Arachidonic Acids; Calcimycin; Concanavalin A; Cyclic N-Oxides; Cytochrome c Group; Cytoplasmic Granules; Humans; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Opsonin Proteins; Spin Labels; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1990 |
Evidence for sequential signals in the induction of the arachidonic acid cascade in macrophages.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium; Cells, Cultured; Choline; Enzyme Activation; Female; Macrophages; Mice; Mice, Inbred ICR; Phospholipases; Protein Biosynthesis; Receptors, Fc; RNA; Sodium; Zymosan | 1986 |
Interferons inhibit LTC4 production in murine macrophages.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Depression, Chemical; Female; Gene Expression Regulation; Interferons; Macrophages; Male; Mice; Mice, Inbred C3H; Peritoneal Cavity; Recombinant Fusion Proteins; SRS-A; Zymosan | 1987 |
Phospholipid and arachidonic acid metabolism in zymosan-stimulated human monocytes: modulation by cAMP.
Topics: 1-Methyl-3-isobutylxanthine; Arachidonic Acid; Arachidonic Acids; Bucladesine; Cyclic AMP; Humans; Lysosomes; Membrane Lipids; Monocytes; Phospholipases A; Phospholipids; Type C Phospholipases; Zymosan | 1987 |
A role for protein kinase C-mediated phosphorylation in the mobilization of arachidonic acid in mouse macrophages.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Electrophoresis, Polyacrylamide Gel; Female; Lipopolysaccharides; Macrophages; Mice; Phosphoproteins; Protein Kinase C; Tetradecanoylphorbol Acetate; Zymosan | 1989 |
Characteristics of oedema formation induced by N-formyl-methionyl-leucyl-phenylalanine in rabbit skin.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Bradykinin; Colchicine; Dinoprostone; Edema; Endotoxins; Histamine; Ibuprofen; Male; N-Formylmethionine Leucyl-Phenylalanine; Rabbits; Skin Diseases; Zymosan | 1989 |
Acetylated low density lipoproteins promote the release and metabolism of arachidonic acid by murine macrophages.
Topics: Acetylation; Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Cell Adhesion Molecules; In Vitro Techniques; Kinetics; Lipoproteins, LDL; Macrophages; Male; Mice; Receptors, LDL; Receptors, Scavenger; Structure-Activity Relationship; Zymosan | 1989 |
Stimulus-specific production of cyclooxygenase and lipoxygenase metabolites of arachidonic acid by bovine alveolar macrophages.
Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Bronchoalveolar Lavage Fluid; Calcimycin; Cattle; Cells, Cultured; Macrophages; Male; Prostaglandin-Endoperoxide Synthases; Pulmonary Alveoli; Tetradecanoylphorbol Acetate; Zymosan | 1989 |
Extracellular phospholipase A2 activity in cell free peritoneal lavage fluid from mice with zymosan peritonitis.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Male; Mice; Peritonitis; Phospholipases; Phospholipases A; Phospholipases A2; SRS-A; Therapeutic Irrigation; Time Factors; Zymosan | 1989 |
Multiple defects in arachidonate metabolism in alveolar macrophages from young asymptomatic smokers.
Topics: Adenosine Triphosphate; Antioxidants; Arachidonic Acid; Arachidonic Acids; Bronchoalveolar Lavage Fluid; Calcimycin; Cells, Cultured; Chromatography, High Pressure Liquid; Eicosanoids; Lipids; Macrophages; Monocytes; Oxygenases; Phospholipases; Radioimmunoassay; Smoking; Zymosan | 1989 |
Biosynthesis of paf-acether. Paf-acether but not leukotriene C4 production is impaired in cultured macrophages.
Topics: Acetyltransferases; Animals; Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Chromatography, High Pressure Liquid; Female; Macrophages; Mice; Mice, Inbred C57BL; Peritoneal Cavity; Platelet Activating Factor; SRS-A; Zymosan | 1989 |
Different patterns of arachidonate metabolism in autologous human blood monocytes and alveolar macrophages.
Topics: Adenosine Triphosphate; Adult; Aerobiosis; Arachidonic Acid; Arachidonic Acids; Calcimycin; Cells, Cultured; Drug Combinations; Female; Humans; Leukotriene B4; Macrophages; Male; Monocytes; Pulmonary Alveoli; SRS-A; Zymosan | 1989 |
Virus-induced enhancement of arachidonate metabolism by bovine alveolar macrophages in vitro.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Cattle; Macrophages; Male; Parainfluenza Virus 3, Human; Paramyxoviridae Infections; Phospholipids; Pulmonary Alveoli; Tetradecanoylphorbol Acetate; Tritium; Zymosan | 1989 |
Studies on the mechanisms of granulocyte dysfunctions in severely burned patients--evidence for altered leukotriene generation.
Topics: Adult; Aged; Aged, 80 and over; Arachidonic Acid; Arachidonic Acids; Burns; Calcimycin; Chromatography, High Pressure Liquid; Female; Free Radicals; Granulocytes; Humans; Leukotriene B4; Luminescent Measurements; Male; Middle Aged; Oxidation-Reduction; Zymosan | 1989 |
Effects of inadequate vitamin E and/or selenium nutrition on the release of arachidonic acid metabolites in rat alveolar macrophages.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Dinoprostone; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Lipoxygenase; Macrophages; Male; Prostaglandin-Endoperoxide Synthases; Pulmonary Alveoli; Rats; Selenium; Thromboxane B2; Vitamin E; Vitamin E Deficiency; Zymosan | 1989 |
Inhibitory effects of methyl 7-butyl-4,5,6,7-tetrahydro-3-methylamino-4,6-dioxo-5-propyl- 2H-pyrazolo[3,4-d]pyrimidine-2-carboxylate (AA-2379) on lysosomal enzyme and arachidonic acid release from rat polymorphonuclear leukocytes and its mode of action.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arachidonic Acids; Cyclic AMP; Glucuronidase; Lysosomes; Male; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pyrimidines; Rats; Rats, Inbred Strains; Zymosan | 1989 |
Effects of sulfasalazine and a sulfasalazine analogue on the formation of lipoxygenase and cyclooxygenase products.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Aminosalicylic Acid; Aminosalicylic Acids; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcimycin; Chromatography, High Pressure Liquid; Dinoprostone; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Leukocytes; Leukotriene B4; Lipoxygenase; Mesalamine; Prostaglandin-Endoperoxide Synthases; Sulfapyridine; Sulfasalazine; Zymosan | 1989 |
Leukotriene B4 paradox: neutrophils can, but will not, respond to ligand-receptor interactions by forming leukotriene B4 or its omega-metabolites.
Topics: Adult; Arachidonic Acid; Arachidonic Acids; Humans; Immunoglobulin G; In Vitro Techniques; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase C; Receptors, Immunologic; Zymosan | 1987 |
Release of lysosomal enzymes is not correlated with superoxide and prostaglandin production by stimulated rat Kupffer cells in primary culture.
Topics: Acetylglucosaminidase; Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Cells, Cultured; Dinoprostone; Glucosephosphate Dehydrogenase; Glucuronidase; Hexosaminidases; Kupffer Cells; L-Lactate Dehydrogenase; Male; Phorbol Esters; Prostaglandins E; Rats; Rats, Inbred Strains; Stimulation, Chemical; Superoxides; Zymosan | 1988 |
Arachidonic acid metabolism by a vitamin D3-differentiated human leukemic cell line.
Topics: Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcitriol; Cell Division; Cell Fractionation; Dimethyl Sulfoxide; Humans; Leukemia; Leukotriene B4; Lipids; N-Formylmethionine Leucyl-Phenylalanine; Radioimmunoassay; Thromboxane B2; Tumor Cells, Cultured; Zymosan | 1988 |
Desensitization of macrophage oxygen metabolism on immobilized ligands: different effect of immunoglobulin G and complement.
Topics: Animals; Antigen-Antibody Complex; Arachidonic Acid; Arachidonic Acids; Cell Adhesion; Cells, Cultured; Complement C3; Culture Techniques; Female; Immunoglobulin G; Macrophage Activation; Macrophages; Male; Mice; Oxygen; Phagocytosis; Receptors, Fc; Receptors, IgG; Tetradecanoylphorbol Acetate; Zymosan | 1987 |
Evaluation of the antiinflammatory and phospholipase-inhibitory activity of calpactin II/lipocortin I.
Topics: Animals; Annexins; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arachidonic Acids; Calcium-Binding Proteins; Edema; Female; Glycoproteins; Humans; Male; Phospholipases; Pregnancy; Pregnancy Proteins; Rats; Rats, Inbred Strains; Zymosan | 1988 |
Intracellular retention of the 5-lipoxygenase pathway product, leukotriene B4, by human neutrophils activated with unopsonized zymosan.
Topics: Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Calcimycin; Humans; Hydroxyeicosatetraenoic Acids; Kinetics; Leukotriene B4; Lipoxygenase; Neutrophils; Opsonin Proteins; Phagocytosis; Zymosan | 1985 |
Effects of various inhibitors of arachidonic acid oxygenation on macrophage superoxide release and tumoricidal activity.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Auranofin; Aurothioglucose; Cells, Cultured; Cyclooxygenase Inhibitors; Cytotoxicity, Immunologic; Lipoxygenase Inhibitors; Lymphokines; Macrophage Activation; Macrophage-Activating Factors; Macrophages; Male; Mice; Neoplasms, Experimental; Phagocytosis; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1985 |
Intracellular Ca2+ requirements for zymosan-stimulated phosphoinositide hydrolysis in mouse peritoneal macrophages.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium; Catechols; Enzyme Activation; Indomethacin; Macrophages; Male; Masoprocol; Mice; Phosphatidylinositols; Time Factors; Type C Phospholipases; Zymosan | 1986 |
The effect of carbaryl on the arachidonic acid metabolism and superoxide production by mouse resident peritoneal macrophages challenged by zymosan.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Carbaryl; In Vitro Techniques; Indomethacin; L-Lactate Dehydrogenase; Macrophages; Male; Membrane Lipids; Mice; Superoxides; Zymosan | 1986 |
Inhibition of the oxidative burst in human neutrophils by sphingoid long-chain bases. Role of protein kinase C in activation of the burst.
Topics: Arachidonic Acid; Arachidonic Acids; Calcium; Cell Membrane; Cell Survival; Cytochrome c Group; Dose-Response Relationship, Drug; Humans; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Oxygen Consumption; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Sphingosine; Tetradecanoylphorbol Acetate; Zymosan | 1986 |
Differential effects of mepacrine, chloroquine and hydroxychloroquine on superoxide anion generation, phospholipid methylation and arachidonic acid release by human blood monocytes.
Topics: Arachidonic Acid; Arachidonic Acids; Calcimycin; Cell Survival; Chloroquine; Fluorides; Humans; Hydroxychloroquine; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Phospholipids; Quinacrine; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1986 |
Enhanced release of hydrogen peroxide and metabolites of arachidonic acid by macrophages from SENCAR mice following stimulation with phorbol esters.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Caseins; Hydrogen Peroxide; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Macrophages; Mice; Mice, Inbred Strains; Phorbol Esters; Prostaglandins; SRS-A; Zymosan | 1986 |
Identification of distinct activation pathways of the human neutrophil NADPH-oxidase.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Arachidonic Acid; Arachidonic Acids; Aspirin; Calcium; Enzyme Activation; Humans; Indomethacin; Isoquinolines; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Phospholipases A; Phospholipases A2; Phospholipids; Piperazines; Pyrazoles; Quinacrine; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1986 |
Relationship of glucocorticoid suppression of arachidonic acid metabolism to alteration of neutrophil function.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Cattle; Dexamethasone; Diglycerides; Hydroxyeicosatetraenoic Acids; Indomethacin; Leukotriene B4; Masoprocol; Neutrophils; Phospholipids; Pyrazoles; Triglycerides; Zymosan | 1987 |
The leukotriene B4 paradox: neutrophils can, but will not, respond to ligand-receptor interactions by forming leukotriene B4 or its omega-metabolites.
Topics: Arachidonic Acid; Arachidonic Acids; Humans; Immunoglobulin G; Leukotriene B4; Ligands; Linoleic Acid; Linoleic Acids; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Receptors, Drug; Tetradecanoylphorbol Acetate; Zymosan | 1987 |
Inhibition by methylprednisolone of zymosan-induced leukotriene synthesis in alveolar macrophages.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Chromatography, High Pressure Liquid; Depression, Chemical; Female; Gonadal Steroid Hormones; Leukotriene B4; Macrophages; Methylprednisolone; Pulmonary Alveoli; Radioimmunoassay; Rats; Rats, Inbred Strains; SRS-A; Thromboxane B2; Zymosan | 1987 |
The role of beta-glucan receptors on blood and tissue leukocytes in phagocytosis and metabolic activation.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Humans; Macrophages; Mice; Monocytes; Phagocytes; Receptors, Cell Surface; Receptors, Immunologic; Zymosan | 1986 |
Changes in the incorporation of free fatty acids upon the stimulation of human polymorphonuclear leukocytes.
Topics: Acylation; Acyltransferases; Arachidonic Acid; Arachidonic Acids; Calcimycin; Carbon Radioisotopes; Catechols; Fatty Acids, Nonesterified; Glycerol; Humans; In Vitro Techniques; Luminescent Measurements; Masoprocol; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipids; Zymosan | 1986 |
Regulation of macrophage eicosanoid production by hydroperoxy-and hydroxy-eicosatetraenoic acids.
Topics: Acetylglucosaminidase; Animals; Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Dinoprostone; Female; Hydroxyeicosatetraenoic Acids; Leukotrienes; Lipid Peroxides; Macrophages; Mice; Prostaglandins E; SRS-A; Zymosan | 1986 |
The influence of phagocytic stimuli on the expression of HLA-DR antigens; role of reactive oxygen intermediates.
Topics: Adult; Antigen-Presenting Cells; Arachidonic Acid; Arachidonic Acids; beta Carotene; Carotenoids; Histocompatibility Antigens Class II; HLA Antigens; HLA-DQ Antigens; HLA-DR Antigens; Humans; Indomethacin; Luminescent Measurements; Monocytes; Oxygen; Phagocytosis; Superoxide Dismutase; Zymosan | 1986 |
Dexamethasone and hydrogen peroxide production by mesangial cells during phagocytosis.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Cycloheximide; Dactinomycin; Dexamethasone; Dinoprostone; Estrenes; Hydrogen Peroxide; Kidney Glomerulus; Mifepristone; Phagocytosis; Prostaglandins E; Rats; Zymosan | 1986 |
Evidence for a catalytic role of phospholipase A in phorbol diester- and zymosan-induced mobilization of arachidonic acid in mouse peritoneal macrophages.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Ascitic Fluid; Chlorpromazine; Macrophages; Mice; Phloretin; Phorbol Esters; Phosphatidylinositols; Phospholipases; Phospholipases A; Tetradecanoylphorbol Acetate; Type C Phospholipases; Umbelliferones; Zymosan | 1986 |
Relative degradation of different arachidonoyl molecular species of choline glycerophospholipids in opsonized zymosan-stimulated rabbit alveolar macrophages.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Chromatography, High Pressure Liquid; Macrophages; Opsonin Proteins; Phosphatidylcholines; Pulmonary Alveoli; Rabbits; Time Factors; Zymosan | 1986 |
Release of arachidonic acid and formation of oxygenated derivatives after complement attack on macrophages: role of channel formation.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Cell Survival; Chromatography, High Pressure Liquid; Complement C5; Complement C5a; Complement Membrane Attack Complex; Complement System Proteins; Dose-Response Relationship, Immunologic; Macrophages; Melitten; Mice; Mice, Inbred C3H; Oxygen; Prostaglandins F; Zymosan | 1986 |
Differential alteration of lipoxygenase and cyclooxygenase metabolism by rat peritoneal macrophages induced by endotoxin tolerance.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Dinoprostone; Drug Tolerance; Endotoxins; Glucans; Lipoxygenase; Macrophages; Phospholipases A; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; Rats; Shock, Septic; SRS-A; Thromboxane B2; Zymosan | 1986 |
Studies on the activities of tannins and related compounds; VIII. Effects of geraniin, corilagin, and ellagic acid isolated from geranii herba on arachidonate metabolism in leukocytes.
Topics: Arachidonic Acid; Arachidonic Acids; Benzopyrans; Ellagic Acid; Glucosides; Glycosides; Humans; Hydrolyzable Tannins; In Vitro Techniques; Leukocytes; Tannins | 1986 |
In vitro formation of activators for prostaglandin synthesis by neutrophils and macrophages from humans and guinea pigs.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Catalase; Enzyme Activation; Glutathione Peroxidase; Guinea Pigs; HEPES; Humans; Hydrogen Peroxide; Leukotrienes; Macrophages; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Tetradecanoylphorbol Acetate; Zymosan | 1986 |
Arachidonic acid turnover in response to lipopolysaccharide and opsonized zymosan in human monocyte-derived macrophages.
Topics: Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Fatty Acids; Humans; Lipopolysaccharides; Macrophages; Opsonin Proteins; Phosphatidylcholines; Phospholipids; Platelet Activating Factor; Zymosan | 1986 |
Possible involvement of prostaglandins in vasoconstriction induced by zymosan and arachidonic acid in the perfused rat liver.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blood Pressure; Latex; Liver; Perfusion; Phenylephrine; Portal Vein; Prostaglandins; Rats; Rats, Inbred Strains; Vasoconstriction; Zymosan | 1987 |
Possible involvement of eicosanoids in the zymosan and arachidonic-acid-induced oxygen uptake, glycogenolysis and Ca2+ mobilization in the perfused rat liver.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Glucose; Latex; Liver; Liver Glycogen; Oxygen Consumption; Perfusion; Rats; Rats, Inbred Strains; Zymosan | 1987 |
Effects of caffeoylglycosides on arachidonate metabolism in leukocytes.
Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Caffeic Acids; Glucosides; Glycosides; Humans; Neutrophils; Plant Extracts; Rats | 1987 |
Modulation of alveolar macrophage-derived 5-lipoxygenase products by the sulfhydryl reactant, N-ethylmaleimide.
Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Calcimycin; Ethylmaleimide; Female; Glutathione; Indomethacin; Macrophages; Prostaglandin-Endoperoxide Synthases; Pulmonary Alveoli; Rats; Rats, Inbred Strains; SRS-A; Thromboxanes; Zymosan | 1987 |
Platelet-activating factor induces leukotriene C4 synthesis by purified human eosinophils.
Topics: Arachidonic Acid; Arachidonic Acids; Calcimycin; Chromatography, High Pressure Liquid; Drug Synergism; Eosinophils; Humans; Platelet Activating Factor; Radioimmunoassay; SRS-A; Time Factors; Zymosan | 1987 |
Effect of selected antiinflammatory agents and other drugs on zymosan, arachidonic acid, PAF and carrageenan induced paw edema in the mouse.
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Carrageenan; Drug Evaluation, Preclinical; Edema; Female; Mice; Platelet Activating Factor; Zymosan | 1987 |
Hydrogen-peroxide-induced arachidonic acid metabolism in the rat alveolar macrophage.
Topics: Animals; Antioxidants; Arachidonic Acid; Arachidonic Acids; Calcimycin; Catalase; Dinoprostone; Female; Hydrogen Peroxide; Macrophages; Prostaglandins E; Pulmonary Alveoli; Rats; Rats, Inbred Strains; Thromboxane A2; Zymosan | 1988 |
Protein kinase C mediates endotoxin and zymosan-induced prostaglandin synthesis.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cell Wall; Dinoprostone; Endotoxins; Leukemia, Experimental; Mice; Prostaglandins; Prostaglandins E; Protein Kinase C; Tetradecanoylphorbol Acetate; Zymosan | 1987 |
Inability of murine peritoneal macrophages to convert linoleic acid into arachidonic acid. Evidence of chain elongation.
Topics: Acetyltransferases; Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Carbon Radioisotopes; Fatty Acid Elongases; Fatty Acids; Female; Linoleic Acid; Linoleic Acids; Macrophages; Mice; Mice, Inbred C57BL; Peritoneal Cavity; Phospholipids; Tetradecanoylphorbol Acetate; Zymosan | 1988 |
Effect of chemotactic factors on hexose transport in polymorphonuclear leucocytes.
Topics: 3-O-Methylglucose; Arachidonic Acid; Arachidonic Acids; Biological Transport; Blood; Calcimycin; Chemotactic Factors; Deoxyglucose; Glucose; Hexoses; Humans; Kinetics; Methylglucosides; Monosaccharide Transport Proteins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Tetradecanoylphorbol Acetate; Thrombin; Zymosan | 1988 |
Selective inhibition of free arachidonic acid production in activated alveolar macrophages by calmodulin antagonists.
Topics: Acetophenones; Animals; Arachidonic Acid; Arachidonic Acids; Calmodulin; Chlorpromazine; Chromatography, High Pressure Liquid; Cytochalasin B; Linoleic Acid; Linoleic Acids; Macrophage Activation; Macrophages; Oleic Acid; Oleic Acids; Opsonin Proteins; Phosphatidylcholines; Phosphatidylinositols; Phospholipases A; Pulmonary Alveoli; Quinacrine; Rabbits; Sulfonamides; Trifluoperazine; Zymosan | 1988 |
Regulation of eicosanoid biosynthesis in vitro and in vivo by the marine natural product manoalide: a potent inactivator of venom phospholipases.
Topics: 6-Ketoprostaglandin F1 alpha; Analgesics; Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Dinoprostone; In Vitro Techniques; Macrophages; Male; Mice; Phospholipases; Phospholipases A; Phospholipases A2; SRS-A; Terpenes; Tetradecanoylphorbol Acetate; Zymosan | 1988 |
[1-14C]Arachidonic acid incorporation into glycerolipids and prostaglandin synthesis in peritoneal macrophages: effect of chloramphenicol.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Chloramphenicol; Dose-Response Relationship, Drug; Indomethacin; Macrophages; Male; Membrane Lipids; Mice; Prostaglandins; Zymosan | 1985 |
Intracellular calcium does not appear to be essential for arachidonic acid release from stimulated macrophages as shown by studies with Quin-2.
Topics: Aminoquinolines; Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Egtazic Acid; In Vitro Techniques; Lipids; Macrophage Activation; Macrophages; Male; Mice; Tetradecanoylphorbol Acetate; Zymosan | 1985 |
Modulation by hydroxyeicosatetraenoic acids (HETEs) of arachidonic acid metabolism in mouse resident peritoneal macrophages.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Dinoprostone; Female; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Macrophages; Mice; Prostaglandins E; SRS-A; Thromboxane B2; Zymosan | 1985 |
Arachidonic acid metabolites as mediators of lung injury during intravascular complement activation.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Blood Gas Analysis; Cell Adhesion; Complement Activation; Hypertension, Pulmonary; Leukocytes; Lung; Prostaglandin-Endoperoxide Synthases; Sheep; Thromboxane B2; Zymosan | 1985 |
Arachidonic acid metabolites regulate interleukin-1 production.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Catechols; Dinoprostone; Drug Synergism; Female; Indomethacin; Interleukin-1; Lipopolysaccharides; Masoprocol; Mice; Mice, Inbred CBA; Prostaglandins E; Zymosan | 1985 |
Calcium ionophore enables soluble agonists to stimulate macrophage 5-lipoxygenase.
Topics: Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Calcimycin; Enzyme Activation; In Vitro Techniques; Latex; Lipoxygenase; Macrophages; Mice; Mice, Inbred C57BL; Prostaglandin-Endoperoxide Synthases; SRS-A; Tetradecanoylphorbol Acetate; Zymosan | 1985 |
Regulation of arachidonic acid metabolism in macrophages by immune and nonimmune interferons.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Dinoprostone; Female; Interferon Type I; Interferon-gamma; Macrophages; Male; Mice; Mice, Inbred C3H; Prostaglandins E; Prostaglandins F; Tetradecanoylphorbol Acetate; Thromboxane B2; Zymosan | 1985 |
Thromboxane synthase is preferentially conserved in activated mouse peritoneal macrophages.
Topics: Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Cytochrome P-450 Enzyme System; Epoprostenol; Indomethacin; Intramolecular Oxidoreductases; Lipoxygenase; Listeria; Macrophage Activation; Macrophages; Mice; Oxidoreductases; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandin-Endoperoxide Synthases; Prostaglandins H; SRS-A; Thromboxane-A Synthase; Zymosan | 1985 |
The different response of guinea pig peritoneal macrophages to various stimulators.
Topics: Actinomyces; Animals; Arachidonic Acid; Arachidonic Acids; Ascitic Fluid; Calcimycin; Dinoprostone; Guinea Pigs; Kinetics; Macrophages; Male; Phospholipids; Prostaglandins E; Thromboxane B2; Zymosan | 1985 |
Dynamics of arachidonic acid metabolism in macrophages from delayed-type hypersensitivity (Schistosoma mansoni egg) and foreign-body-type granulomas.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Female; Foreign-Body Reaction; Granuloma; Hypersensitivity, Delayed; Kinetics; Lung Diseases; Macrophage Activation; Macrophages; Mice; Mice, Inbred CBA; Ovum; Phospholipids; Schistosomiasis mansoni; Zymosan | 1985 |
Mechanism of cyclosporin A-induced inhibition of prostacyclin synthesis by macrophages.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Cyclosporins; Depression, Chemical; Dexamethasone; Epoprostenol; In Vitro Techniques; Indomethacin; Macrophage Activation; Macrophages; Male; Phospholipases A; Phospholipases A2; Rats; Rats, Inbred Strains; Zymosan | 1985 |
Regulation of the human polymorphonuclear leukocyte inflammatory response by inhibitors of arachidonic acid metabolism.
Topics: Anticoagulants; Antioxidants; Arachidonic Acid; Arachidonic Acids; Catechols; Cytochrome c Group; Eicosapentaenoic Acid; Fatty Acids, Unsaturated; Glucuronidase; Humans; In Vitro Techniques; Indomethacin; Inflammation; Luminescent Measurements; Lysosomes; Masoprocol; Neutrophils; Oxidation-Reduction; Oxygen Consumption; Superoxides; Xanthine Oxidase; Zymosan | 1984 |
Synthesis of leukotriene C and other arachidonic acid metabolites by mouse pulmonary macrophages.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Chromatography, High Pressure Liquid; Female; gamma-Glutamyltransferase; Lipid Metabolism; Lung; Macrophages; Male; Mice; Mice, Inbred ICR; Phagocytosis; Phospholipids; Pulmonary Alveoli; SRS-A; Zymosan | 1982 |
Phospholipid turnover during phagocytosis in human polymorphonuclear leucocytes.
Topics: 1-Methyl-3-isobutylxanthine; Arachidonic Acid; Arachidonic Acids; Diacylglycerol Cholinephosphotransferase; Humans; In Vitro Techniques; Neutrophils; Phagocytosis; Phosphatidylcholines; Phospholipids; Quinacrine; Zymosan | 1982 |
Identification of two monohydroxyeicosatetraenoic acids synthesized by human pulmonary macrophages.
Topics: Adult; Arachidonic Acid; Arachidonic Acids; Calcimycin; Chromatography, High Pressure Liquid; Female; Humans; Leukotriene B4; Lipoxygenase; Lung; Macrophages; Male; Stimulation, Chemical; Zymosan | 1982 |
Physiological and pharmacological regulation of prostaglandin and leukotriene production by macrophages.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Cyclooxygenase Inhibitors; Dapsone; Leukotriene B4; Macrophages; Mice; Prostaglandins; Sulindac; Zymosan | 1984 |
Release of leukotrienes by human monocytes on stimulation of their phagocytic receptor for particulate activators.
Topics: Arachidonic Acid; Arachidonic Acids; Calcimycin; Erythrocytes; Humans; Leukotriene B4; Monocytes; Opsonin Proteins; Phagocytosis; Receptors, IgG; Receptors, Immunologic; Trypsin; Zymosan | 1984 |
Mechanism of arachidonic acid release in human polymorphonuclear leukocytes.
Topics: Arachidonic Acid; Arachidonic Acids; Calcimycin; Carbon Radioisotopes; Humans; Kinetics; Neutrophils; Phospholipids; Stearic Acids; Tritium; Zymosan | 1983 |
Arachidonic acid metabolism by human monocytes. Studies with platelet-depleted cultures.
Topics: Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcimycin; Cell Separation; Cells, Cultured; Fatty Acids; Humans; Immunoglobulin G; Kinetics; Monocytes; Phospholipids; Prostaglandin-Endoperoxide Synthases; Rosette Formation; Time Factors; Zymosan | 1983 |
Effect of fatty acid anilides on the generation of arachidonic acid by human polymorphonuclear leukocytes.
Topics: Anilides; Arachidonic Acid; Arachidonic Acids; Calcimycin; Dose-Response Relationship, Drug; Humans; Kinetics; Linoleic Acids; Neutrophils; Oleic Acids; Triglycerides; Zymosan | 1983 |
Effect of platelet-activating factor and serum-treated zymosan on prostaglandin E2 synthesis, arachidonic acid release, and contraction of cultured rat mesangial cells.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Dinoprostone; Dose-Response Relationship, Drug; Glomerular Mesangium; Phagocytosis; Platelet Activating Factor; Prostaglandins E; Rats; Zymosan | 1984 |
Sex differences in arachidonate cyclo-oxygenase products in elicited rat peritoneal macrophages.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Dinoprostone; Female; Macrophages; Male; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; Rats; Rats, Inbred F344; Sex Characteristics; Thromboxane B2; Zymosan | 1984 |
1-O-alkyl-2-arachidonoyl-sn-glycero-3-phosphocholine. A common source of platelet-activating factor and arachidonate in human polymorphonuclear leukocytes.
Topics: Arachidonic Acid; Arachidonic Acids; Calcimycin; Chromatography, High Pressure Liquid; Humans; Models, Biological; Neutrophils; Phosphatidylcholines; Phospholipid Ethers; Platelet Activating Factor; Time Factors; Zymosan | 1984 |
Arachidonic acid-mediated and serum-opsonized-zymosan-mediated inhibition of complement production by macrophages. Lack of requirement for endogenous arachidonic acid metabolites.
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Complement C2; Complement C4; Complement System Proteins; Cyclooxygenase Inhibitors; Female; Guinea Pigs; Kinetics; Lipoxygenase Inhibitors; Macrophages; Male; Muramidase; Phagocytosis; Zymosan | 1984 |
Glucocorticoid inhibition of zymosan-induced arachidonic acid release by rat alveolar macrophages.
Topics: Animals; Annexins; Arachidonic Acid; Arachidonic Acids; Calcium-Binding Proteins; Dexamethasone; Dose-Response Relationship, Drug; Female; Fluocinolone Acetonide; Glucocorticoids; Glycoproteins; Gonadal Steroid Hormones; Hydrocortisone; Lymphokines; Macrophages; Protein Biosynthesis; Pulmonary Alveoli; Rats; Rats, Inbred Strains; Time Factors; Zymosan | 1984 |
Regulation of arachidonic acid metabolism by macrophage activation.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; BCG Vaccine; Culture Media; Female; Immunity, Cellular; Inflammation; Injections, Intraperitoneal; Injections, Intravenous; Kinetics; Lymphokines; Macrophage Activation; Mice; Mice, Inbred ICR; Phagocytosis; Propionibacterium acnes; Prostaglandins; Zymosan | 1982 |
Arachidonic acid metabolism in glutathione-deficient macrophages.
Topics: Arachidonic Acid; Arachidonic Acids; Cell Survival; Epoprostenol; Glutathione; Macrophages; Phagocytosis; Prostaglandins; Prostaglandins E; Zymosan | 1982 |
Phagocytosis-stimulated macrophages. Production of prostaglandins and SRS-A, and prostaglandin effects on macrophage activation.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Dinoprostone; Guinea Pigs; Hexosephosphates; Hydrolases; Lysosomes; Macrophage Activation; Macrophages; Mice; Phagocytosis; Prostaglandins; Prostaglandins E; SRS-A; Zymosan | 1982 |
Acrolein: a potent modulator of lung macrophage arachidonic acid metabolism.
Topics: Acrolein; Aldehydes; Animals; Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Dinoprostone; Dose-Response Relationship, Drug; Female; Macrophages; Phagocytosis; Prostaglandins E; Pulmonary Alveoli; Rats; Rats, Inbred Strains; Sulfhydryl Reagents; Thromboxane B2; Thromboxanes; Zymosan | 1982 |
The pathways of biosynthesis for prostaglandins by the stimulus triggered macrophage.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Carbon Radioisotopes; Culture Techniques; Kinetics; Macrophages; Male; Mice; Phospholipases A; Prostaglandins; Zymosan | 1981 |
Bacterial lipopolysaccharide primes human neutrophils for enhanced release of arachidonic acid and causes phosphorylation of an 85-kD cytosolic phospholipase A2.
Topics: Acute-Phase Proteins; Alkaloids; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Arachidonic Acid; Carrier Proteins; CHO Cells; Cricetinae; Cricetulus; Cytosol; Humans; Leukotriene B4; Lipopolysaccharide Receptors; Lipopolysaccharides; Membrane Glycoproteins; Neutrophils; Phospholipases A; Phospholipases A2; Phospholipids; Phosphorylation; Staurosporine; Tetradecanoylphorbol Acetate; Zymosan | 1994 |
Role of cytosolic phospholipase A2 in arachidonic acid release of rat-liver macrophages: regulation by Ca2+ and phosphorylation.
Topics: Animals; Arachidonic Acid; Calcimycin; Calcium-Calmodulin-Dependent Protein Kinases; Cytosol; Enzyme Activation; Kinetics; Lipopolysaccharides; Liver; Macrophages; Male; Phospholipases A; Phospholipases A2; Phosphorylation; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Zymosan | 1995 |
Stimulus-dependent effects of CI-986 on arachidonic acid metabolism by human neutrophils.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Calcimycin; Chromatography, High Pressure Liquid; Humans; Leukotriene B4; Linear Models; Lipoxygenase Inhibitors; Lysosomes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Respiratory Burst; Thiadiazoles; Thromboxane B2; Zymosan | 1995 |
AA-release is under control of PLA2 and DAG lipase in rat liver macrophages.
Topics: Animals; Arachidonic Acid; Calcimycin; Calcium; Cyclohexanones; Fluorides; Isoenzymes; Kinetics; Kupffer Cells; Lipoprotein Lipase; Phospholipases A; Phospholipases A2; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Zymosan | 1995 |
Effects of the release of arachidonic acid from 1-ether-linked phospholipids on opsonized-zymosan stimulated rabbit alveolar macrophages.
Topics: Animals; Arachidonic Acid; Carbon Radioisotopes; Macrophage Activation; Macrophages, Alveolar; Male; Phospholipid Ethers; Rabbits; Tritium; Zymosan | 1995 |
Nitric oxide activates the glucose-dependent mobilization of arachidonic acid in a macrophage-like cell line (RAW 264.7) that is largely mediated by calcium-independent phospholipase A2.
Topics: Animals; Arachidonic Acid; Calcium; Cell Line; Egtazic Acid; Kinetics; Lipopolysaccharides; Macrophages; Naphthalenes; Nitric Oxide; Nitroprusside; Phospholipases A; Phospholipases A2; Phospholipids; Pyrones; Second Messenger Systems; Tritium; Zymosan | 1995 |
Immunochemical relatedness between secretory phospholipase A2 and intracellular phospholipase A2 activity linked with arachidonic acid mobilization in macrophages.
Topics: Acetophenones; Animals; Arachidonic Acid; Aristolochic Acids; Blotting, Western; Cross Reactions; Crotalid Venoms; Crotalus; Elapid Venoms; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Immune Sera; Macrophages, Peritoneal; Male; Masoprocol; Mice; Molecular Weight; Pancreas; Phagocytosis; Phenanthrenes; Phospholipases A; Phospholipases A2; Rats; Rats, Sprague-Dawley; Swine; Tretinoin; Zymosan | 1994 |
Regulation of cytosolic phospholipase A2 phosphorylation and eicosanoid production by colony-stimulating factor 1.
Topics: Animals; Arachidonic Acid; Calcimycin; Calcium-Calmodulin-Dependent Protein Kinases; Cell Cycle; Cytosol; Drug Synergism; Eicosanoids; Enzyme Activation; Macrophage Colony-Stimulating Factor; Macrophages, Peritoneal; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phospholipases A; Phospholipases A2; Phosphorylation; Protein-Tyrosine Kinases; Tetradecanoylphorbol Acetate; Zymosan | 1994 |
Protein kinase C-dependent and -independent pathways of mitogen-activated protein kinase activation in macrophages by stimuli that activate phospholipase A2.
Topics: Animals; Arachidonic Acid; Calcimycin; Calcium-Calmodulin-Dependent Protein Kinases; Down-Regulation; Enzyme Activation; Ethers, Cyclic; Gene Expression Regulation, Enzymologic; Indoles; Isoenzymes; Macrophages, Peritoneal; Maleimides; Mice; Okadaic Acid; Phospholipases A; Phospholipases A2; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase C; Protein Kinase C-alpha; Signal Transduction; Tetradecanoylphorbol Acetate; Tyrosine; Zymosan | 1994 |
Acyl-chain selectivity of the 85 kDa phospholipase A2 and of the release process in intact macrophages.
Topics: Animals; Arachidonic Acid; Calcimycin; Cell Line; Cells, Cultured; Fatty Acids; Indomethacin; Liposomes; Macrophages, Peritoneal; Mice; Molecular Weight; Phosphatidylethanolamines; Phosphatidylinositols; Phospholipases A; Phospholipases A2; Phospholipids; Serum Albumin, Bovine; Substrate Specificity; Zymosan | 1994 |
Dual pertussis toxin-sensitive pathway of zymosan-induced activation in guinea pig macrophages. An anti-CR3 antibody-inhibitable stimulation of phagocytosis and -resistant stimulation of O2- production and arachidonate release.
Topics: Animals; Arachidonic Acid; Binding Sites; Cells, Cultured; GTP-Binding Proteins; Guinea Pigs; Immunoglobulin Fab Fragments; Macrophage Activation; Macrophage-1 Antigen; Macrophages; N-Formylmethionine Leucyl-Phenylalanine; Opsonin Proteins; Pertussis Toxin; Phagocytosis; Superoxides; Virulence Factors, Bordetella; Zymosan | 1994 |
Reverse-phase high-performance liquid chromatography analysis of arachidonic acid metabolites in plasma after stimulation of whole blood ex vivo.
Topics: Aged; Animals; Anticoagulants; Arachidonic Acid; Calcimycin; Chromatography, High Pressure Liquid; Eosinophils; Female; Humans; Indoles; Kinetics; Leukotriene Antagonists; Leukotriene B4; Middle Aged; Quinolines; Rabbits; Spectrophotometry, Ultraviolet; Stimulation, Chemical; Synovial Fluid; Time Factors; Zymosan | 1994 |
Increased incorporation of arachidonic acid into phospholipids in zymosan-stimulated mouse peritoneal macrophages.
Topics: Acylation; Animals; Arachidonic Acid; Calcium; Cells, Cultured; Macrophage Activation; Macrophages, Peritoneal; Mice; Pertussis Toxin; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylinositols; Virulence Factors, Bordetella; Zymosan | 1994 |
In vitro pharmacology of BAY X1005, a new inhibitor of leukotriene synthesis.
Topics: Animals; Arachidonic Acid; Calcimycin; Cells, Cultured; Humans; Leukotriene B4; Leukotriene C4; Lipoxygenase Inhibitors; Macrophages, Peritoneal; Methemoglobin; Mice; Mice, Inbred BALB C; Neutrophils; Quinolines; Rats; Rats, Wistar; Reactive Oxygen Species; Stereoisomerism; Xanthine Oxidase; Zymosan | 1993 |
A role for protein kinase C-alpha in zymosan-stimulated eicosanoid synthesis in mouse peritoneal macrophages.
Topics: Alkaloids; Animals; Arachidonic Acid; Cells, Cultured; Dinoprostone; Eicosanoids; Fatty Acids; Isoenzymes; Kinetics; Leukotriene C4; Macrophages, Peritoneal; Mice; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Zymosan | 1993 |
Regulation of phospholipase A2 activation by phosphorylation in mouse peritoneal macrophages.
Topics: Amino Acid Sequence; Animals; Arachidonic Acid; Calcimycin; Cells, Cultured; Enzyme Activation; Ethers, Cyclic; Macrophages; Mice; Molecular Sequence Data; Okadaic Acid; Peptide Mapping; Peritoneal Cavity; Phospholipases A; Phospholipases A2; Phosphorylation; Tetradecanoylphorbol Acetate; Zymosan | 1993 |
Release of prostaglandin E2 by human mononuclear cells exposed to heat-killed Salmonella typhi.
Topics: Arachidonic Acid; Dinoprostone; Hot Temperature; Humans; Models, Biological; Monocytes; Salmonella typhi; Zymosan | 1993 |
Formation of diacylglycerol, inositol phosphates, arachidonic acid and its metabolites in macrophages.
Topics: Animals; Arachidonic Acid; Calcimycin; Cells, Cultured; Cyclohexanones; Diglycerides; Fluorides; Inositol Phosphates; Macrophages; Male; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Zymosan | 1993 |
The requirement for phospholipase A2 for activation of the assembled NADPH oxidase in human neutrophils.
Topics: Acetophenones; Alkaloids; Arachidonic Acid; Biological Transport; Cell Membrane; Enzyme Activation; Humans; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Opsonin Proteins; Phospholipases A; Phospholipases A2; Phosphorylation; Protein Kinase C; Quinacrine; Staurosporine; Superoxides; Tetradecanoylphorbol Acetate; Tritium; Zymosan | 1994 |
Ethanol inhibits zymosan-stimulated eicosanoid production in mouse peritoneal macrophages.
Topics: Acyltransferases; Animals; Arachidonic Acid; Ethanol; Macrophages, Peritoneal; Mice; Pertussis Toxin; Phospholipases A; Phospholipases A2; Virulence Factors, Bordetella; Zymosan | 1994 |
Cloricromene inhibits leukotriene formation by human polymorphonuclear leucocytes by suppressing arachidonate release from membrane phospholipids.
Topics: Arachidonic Acid; Calcimycin; Chromonar; Dose-Response Relationship, Drug; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Membrane Lipids; Neutrophils; Phospholipids; SRS-A; Zymosan | 1993 |
Impaired superoxide anion, platelet-activating factor, and leukotriene B4 synthesis by neutrophils in cirrhosis.
Topics: Adult; Aged; Arachidonic Acid; Calcimycin; Female; Humans; Leukotriene B4; Liver Cirrhosis; Male; Mass Spectrometry; Middle Aged; Neutrophils; Platelet Activating Factor; Superoxides; Zymosan | 1993 |
Differential regulation of phospholipase D and phospholipase C by protein kinase C-beta and -delta in liver macrophages.
Topics: Animals; Arachidonic Acid; Calcimycin; Carcinogens; Enzyme Activation; Fluorides; Inositol Phosphates; Ionophores; Isoenzymes; Liver; Macrophages; Male; Phospholipase D; Protein Kinase C; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Type C Phospholipases; Zymosan | 1995 |
Activation of phospholipase A2 and acylation of lysophospholipids: the major regulators for platelet activating factor production in rat neutrophils.
Topics: Acylation; Animals; Antibodies, Monoclonal; Arachidonic Acid; Enzyme Activation; Lysophospholipids; Male; Neutrophils; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Thimerosal; Triazenes; Zymosan | 1995 |
Inhibition of the production of platelet activating factor and of leukotriene B4 in activated neutrophils by nimesulide due to an elevation of intracellular cyclic adenosine monophosphate.
Topics: 1-Methyl-3-isobutylxanthine; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytochalasin B; Enzyme Inhibitors; Humans; In Vitro Techniques; Isoquinolines; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphodiesterase Inhibitors; Platelet Activating Factor; Protein Kinase Inhibitors; Sulfonamides; Zymosan | 1995 |
Microtubule-active agents mimic lipopolysaccharides in priming macrophages for enhanced arachidonic acid metabolism.
Topics: Animals; Arachidonic Acid; Cells, Cultured; Colchicine; Female; Kinetics; Lipopolysaccharides; Macrophages, Peritoneal; Mice; Mice, Inbred ICR; Microtubules; Nocodazole; Paclitaxel; Tetradecanoylphorbol Acetate; Zymosan | 1996 |
Effect of degree of unsaturation in dietary fatty acids on arachidonic acid mobilization by peritoneal macrophages.
Topics: Animals; Arachidonic Acid; Calcimycin; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fatty Acids, Unsaturated; Fish Oils; Macrophage Activation; Macrophages, Peritoneal; Male; Opsonin Proteins; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Triglycerides; Zymosan | 1996 |
Inhibitory effect of arachidonic acid on platelet-activating factor production in rat neutrophils.
Topics: Acetyl-CoA C-Acetyltransferase; Animals; Arachidonic Acid; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Indomethacin; Male; Neutrophils; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Triazenes; Zymosan | 1996 |
Age-related enhancement of 5-lipoxygenase metabolic capacity in cattle alveolar macrophages.
Topics: 5-Lipoxygenase-Activating Proteins; Aging; Animals; Animals, Newborn; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Bronchoalveolar Lavage Fluid; Calcimycin; Carrier Proteins; Cattle; Female; Macrophage Activation; Macrophages, Alveolar; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Zymosan | 1996 |
The effect of propolis and its components on eicosanoid production during the inflammatory response.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Arachidonic Acid; Caffeic Acids; Cyclooxygenase Inhibitors; Diet; Eicosanoids; Flavanones; Flavonoids; Indomethacin; Inflammation; Lipoxygenase Inhibitors; Macrophages, Peritoneal; Male; Masoprocol; Mice; Mice, Inbred C57BL; Peritoneal Cavity; Phenylethyl Alcohol; Propolis; Quercetin; Urea; Zymosan | 1996 |
Role of kinases and G-proteins on arachidonate release induced by zymosan in mouse peritoneal macrophages.
Topics: Analysis of Variance; Animals; Arachidonic Acid; Aspirin; Cells, Cultured; GTP-Binding Proteins; Macrophages, Peritoneal; Male; Mice; Neomycin; Pertussis Toxin; Phagocytosis; Phosphotransferases; Virulence Factors, Bordetella; Zymosan | 1996 |
Role of the 5-lipoxygenase-activating protein (FLAP) in murine acute inflammatory responses.
Topics: 5-Lipoxygenase-Activating Proteins; Anaphylaxis; Animals; Arachidonic Acid; Carrier Proteins; DNA, Complementary; Edema; Eicosanoids; Hypersensitivity, Delayed; Immunoglobulin E; Inflammation; Macrophages, Peritoneal; Membrane Proteins; Mice; Mice, Knockout; Peritonitis; Peroxidase; Platelet Activating Factor; RNA, Messenger; Transcription, Genetic; Zymosan | 1997 |
Tenidap inhibits 5-lipoxygenase product formation in vitro, but this activity is not observed in three animal models.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Calcimycin; Chemotactic Factors; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Erythrocytes; Humans; Hydroxyeicosatetraenoic Acids; Immunoenzyme Techniques; Indoles; Ionophores; Leukemia, Basophilic, Acute; Leukotriene B4; Leukotriene E4; Lipoxygenase Inhibitors; Neutrophil Activation; Neutrophils; Oxindoles; Rabbits; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Thromboxane B2; Zymosan | 1997 |
Alterations in the free radical generation and nitric oxide release from rat peripheral polymorphonuclear leukocytes following thrombosis.
Topics: Animals; Arachidonic Acid; Cell Hypoxia; Cells, Cultured; Collagen; Epinephrine; Free Radicals; Luminescent Measurements; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Peroxidase; Rats; Rats, Sprague-Dawley; Thrombosis; Zymosan | 1997 |
Regulation of cytosolic phospholipase A2 in arachidonic acid release of rat-liver macrophages.
Topics: Animals; Arachidonic Acid; Calcimycin; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cytosol; Diglycerides; Enzyme Activation; Ionophores; Isoenzymes; Lipopolysaccharides; Lipoprotein Lipase; Liver; Macrophages; Male; Membrane Lipids; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Models, Biological; Phosphatidylinositol Diacylglycerol-Lyase; Phospholipases A; Phospholipases A2; Phosphorylation; Protein Processing, Post-Translational; Rats; Rats, Wistar; Signal Transduction; Tetradecanoylphorbol Acetate; Type C Phospholipases; Zymosan | 1997 |
The role of calcium and phosphorylation of cytosolic phospholipase A2 in regulating arachidonic acid release in macrophages.
Topics: Animals; Arachidonic Acid; Calcium; Cells, Cultured; Macrophage Activation; Macrophages, Peritoneal; Mice; Okadaic Acid; Phospholipases A; Phospholipases A2; Phosphorylation; Signal Transduction; Tetradecanoylphorbol Acetate; Zymosan | 1998 |
Dietary arachidonic acid increases eicosanoid production in the presence of equal amounts of dietary eicosapentaenoic acid.
Topics: Analysis of Variance; Animals; Arachidonic Acid; Dietary Fats, Unsaturated; Eicosanoids; Eicosapentaenoic Acid; Fatty Acids, Unsaturated; Liver; Macrophages, Peritoneal; Male; Mice; Oleic Acid; Olive Oil; Phospholipids; Plant Oils; Safflower Oil; Triglycerides; Zymosan | 1997 |
Exogenous leukotriene B4 (LTB4) inhibits human neutrophil generation of LTB4 from endogenous arachidonic acid during opsonized zymosan phagocytosis.
Topics: Arachidonic Acid; Dose-Response Relationship, Drug; Fatty Alcohols; Glycols; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Neutrophils; Phagocytosis; Zymosan | 1998 |
Involvement of group VI Ca2+-independent phospholipase A2 in protein kinase C-dependent arachidonic acid liberation in zymosan-stimulated macrophage-like P388D1 cells.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Diglycerides; Egtazic Acid; Group VI Phospholipases A2; Indoles; Leukemia P388; Maleimides; Mice; Naphthalenes; Oligonucleotides, Antisense; Organophosphonates; Phospholipases A; Phospholipases A2; Protein Kinase C; Pyrones; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Zymosan | 1999 |
IL-13 induces serine phosphorylation of cPLA2 in mouse peritoneal macrophages leading to arachidonic acid and PGE2 production and blocks the zymosan-induced serine phosphorylation of cPLA2 and eicosanoid production.
Topics: Animals; Arachidonic Acid; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cytosol; Dinoprostone; Female; Flavonoids; Interleukin-13; Lipoxygenase; Macrophages, Peritoneal; Mice; Phospholipases A; Phosphorylation; Precipitin Tests; Prostaglandin-Endoperoxide Synthases; Serine; Signal Transduction; Zymosan | 1999 |
Genetic factors determine the contribution of leukotrienes to acute inflammatory responses.
Topics: Acute Disease; Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Crosses, Genetic; Ear, External; Edema; Indomethacin; Inflammation; Leukotriene C4; Leukotrienes; Mice; Mice, Congenic; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Mutant Strains; Peritonitis; Species Specificity; Zymosan | 2000 |
Phosphatidylinositol 3-kinase in zymosan- and bacteria-induced signalling to mobilisation of arachidonic acid in macrophages.
Topics: Androstadienes; Animals; Arachidonic Acid; Cells, Cultured; Chromones; Enzyme Activation; Enzyme Inhibitors; Female; Inositol Phosphates; Macrophages, Peritoneal; Mice; Mitogen-Activated Protein Kinases; Morpholines; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phospholipases A; Prevotella intermedia; Signal Transduction; Wortmannin; Zymosan | 2000 |
Cytosolic phospholipase A2 is required for macrophage arachidonic acid release by agonists that Do and Do not mobilize calcium. Novel role of mitogen-activated protein kinase pathways in cytosolic phospholipase A2 regulation.
Topics: Animals; Anisomycin; Arachidonic Acid; Calcimycin; Calcium; Cytosol; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Ionophores; Macrophages; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Mitogen-Activated Protein Kinases; NADPH Oxidases; Okadaic Acid; Phospholipase D; Phospholipases A; Phospholipases A2; Phosphorylation; Protein Synthesis Inhibitors; Serine; Tetradecanoylphorbol Acetate; Time Factors; Zymosan | 2000 |
Differential regulation of prostaglandin E2 and thromboxane A2 production in human monocytes: implications for the use of cyclooxygenase inhibitors.
Topics: Arachidonic Acid; Aspirin; Cell Fractionation; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Eicosanoids; Enzyme Induction; Humans; Interphase; Isoenzymes; Kinetics; Lipopolysaccharides; Membrane Proteins; Monocytes; Prostaglandin H2; Prostaglandin-Endoperoxide Synthases; Prostaglandins H; Thromboxane A2; Thromboxane-A Synthase; U937 Cells; Zymosan | 2000 |
Targeted disruption of the leukotriene B(4) receptor in mice reveals its role in inflammation and platelet-activating factor-induced anaphylaxis.
Topics: Anaphylaxis; Animals; Arachidonic Acid; Ear, External; Female; Gene Targeting; Inflammation Mediators; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neutrophils; Peritoneum; Platelet Activating Factor; Receptors, Leukotriene B4; Zymosan | 2000 |
Anti-thrombosis effect of paeoniflorin: evaluated in a photochemical reaction thrombosis model in vivo.
Topics: Animals; Arachidonic Acid; Benzoates; Bridged-Ring Compounds; Cells, Cultured; Endothelium, Vascular; Fibrinolytic Agents; Free Radical Scavengers; Free Radicals; Glucosides; Humans; Monoterpenes; Paeonia; Photochemistry; Phytotherapy; Plant Preparations; Plants, Medicinal; Rats; Rats, Wistar; Thrombosis | 2001 |
Epstein-Barr virus primes human polymorphonuclear leucocytes for the biosynthesis of leukotriene B4.
Topics: Arachidonic Acid; Calcimycin; Calcium Signaling; Enzyme Activation; Epstein-Barr Virus Infections; Herpesvirus 4, Human; Humans; In Vitro Techniques; Ionophores; Leukotriene B4; Mitogen-Activated Protein Kinases; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipases A; Phospholipases A2; Phosphorylation; Virus Replication; Zymosan | 2001 |
Protein kinase Calpha-dependent increase in Ca2+-independent phospholipase A2 in membranes and arachidonic acid liberation in zymosan-stimulated macrophage-like P388D1 cells.
Topics: Animals; Arachidonic Acid; Calcium; Cell Membrane; Cytochalasin D; Isoenzymes; Macrophages; Mice; Nucleic Acid Synthesis Inhibitors; Phospholipases A; Phospholipases A2; Protein Kinase C; Protein Kinase C-alpha; Zymosan | 2002 |
A new dual inhibitor of arachidonate metabolism isolated from Helichrysum italicum.
Topics: Acetophenones; Analgesics; Animals; Arachidonic Acid; Carrageenan; Dose-Response Relationship, Drug; Ear; Edema; Female; Free Radicals; Glucosides; Helichrysum; Hindlimb; Inflammation; Leukotriene B4; Lipid Peroxidation; Mice; Neutrophils; Peroxidase; Phospholipases A; Plant Extracts; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate | 2003 |
[Isolation of resisting thrombus and arteriosclerosis compounds in leaves of Salix matsudana].
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Apigenin; Arachidonic Acid; Arteriosclerosis; Blood Platelets; Drugs, Chinese Herbal; Fibrinolytic Agents; Glucosides; Luteolin; Plant Leaves; Platelet Aggregation; Rats; Salix; Thromboxane B2 | 1999 |
Release of arachidonic acid by stimulation of opsonic receptors in human monocytes: the FcgammaR and the complement receptor 3 pathways.
Topics: Arachidonic Acid; CD11b Antigen; Cells, Cultured; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Flow Cytometry; Glucans; Humans; Immunoblotting; Lectins; Leukocytes, Mononuclear; Macrophage-1 Antigen; Macrophages; Mannans; Monocytes; Ovalbumin; Phagocytosis; Polysaccharides; Protein Binding; Protein Structure, Tertiary; Receptors, IgG; Receptors, Immunologic; Time Factors; Zymosan | 2003 |
Platelet anti-aggregatory effects of coumarins from the roots of Angelica genuflexa and A. gigas.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Angelica; Animals; Arachidonic Acid; Aspirin; Benzopyrans; Blood Platelets; Butyrates; Collagen; Coumarins; Furocoumarins; Glucosides; Herbal Medicine; Heterocyclic Compounds, 3-Ring; Korea; Male; Medicine, East Asian Traditional; Methanol; Nephelometry and Turbidimetry; Plant Extracts; Plant Roots; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley | 2003 |
Cytosolic phospholipase A2 translocates to forming phagosomes during phagocytosis of zymosan in macrophages.
Topics: Animals; Arachidonic Acid; Calcium; Cytosol; Dinoprostone; Endoplasmic Reticulum Chaperone BiP; Green Fluorescent Proteins; Humans; Luminescent Proteins; Macrophages, Peritoneal; Mice; Mice, Inbred ICR; Microscopy, Fluorescence; Phagocytosis; Phagosomes; Protein Transport; Transfection; Zymosan | 2004 |
Arachidonic acid allows SNARE complex formation in the presence of Munc18.
Topics: Animals; Antigens, Surface; Arachidonic Acid; Detergents; Glucosides; In Vitro Techniques; Munc18 Proteins; Nerve Tissue Proteins; Octoxynol; Rats; Signal Transduction; SNARE Proteins; Synaptic Membranes; Synaptosomes; Syntaxin 1; Vesicular Transport Proteins | 2005 |
Spectroscopic characterization of the EF-hand domain of phospholipase C delta1: identification of a lipid interacting domain.
Topics: Amino Acid Sequence; Arachidonic Acid; Binding Sites; Calcium; Circular Dichroism; EF Hand Motifs; Enzyme Activation; Glucosides; Hydrophobic and Hydrophilic Interactions; Isoenzymes; Ligands; Lipid Metabolism; Lipids; Molecular Conformation; Molecular Sequence Data; Phospholipase C delta; Protein Structure, Tertiary; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Tryptophan; Type C Phospholipases | 2005 |
Oxymetazoline inhibits proinflammatory reactions: effect on arachidonic acid-derived metabolites.
Topics: Animals; Arachidonic Acid; Carbon; Cells, Cultured; Dogs; Lipoxygenase Inhibitors; Macrophages, Alveolar; Nasal Decongestants; Oxidative Stress; Oxymetazoline; Particle Size; Phagocytosis; Respiratory Burst; Zymosan | 2006 |
Differential effects of fexofenadine on arachidonic acid metabolism in cultured human monocytes.
Topics: Anti-Allergic Agents; Anti-Inflammatory Agents; Arachidonic Acid; Cells, Cultured; Dinoprostone; Histamine H1 Antagonists; Humans; Leukotrienes; Lipopolysaccharides; Monocytes; Terfenadine; Zymosan | 2006 |
Effects of compounds in leaves of Salix matsudana on arachidonic acid metabolism.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Apigenin; Arachidonic Acid; Blood Platelets; Cells, Cultured; Depression, Chemical; Flavones; Flavonoids; Glucosides; Luteolin; Male; Plant Leaves; Rats; Rats, Wistar; Salix; Structure-Activity Relationship; Thromboxane B2 | 2005 |
Regulation of cytosolic phospholipase A2 activation and cyclooxygenase 2 expression in macrophages by the beta-glucan receptor.
Topics: Animals; Arachidonic Acid; Candida albicans; Cells, Cultured; Cyclooxygenase 2; Eicosanoids; Enzyme Activation; Humans; Intracellular Signaling Peptides and Proteins; Lectins, C-Type; Macrophages, Peritoneal; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Tissue Proteins; Phospholipases A; Phospholipases A2; Protein-Tyrosine Kinases; Receptors, Immunologic; src-Family Kinases; Syk Kinase; Toll-Like Receptor 2; Zymosan | 2006 |
The effect of acteoside on histamine release and arachidonic acid release in RBL-2H3 mast cells.
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Calcium; Calcium-Transporting ATPases; Cell Line, Tumor; Clerodendrum; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Activators; Enzyme Inhibitors; Glucosides; Histamine Release; Mast Cells; Melitten; Phenols; Phospholipases A; Rats; Thapsigargin | 2006 |
Involvement of multitargets in paeoniflorin-induced preconditioning.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Arachidonic Acid; Benzoates; Brain-Derived Neurotrophic Factor; Bridged-Ring Compounds; Glucosides; HSP70 Heat-Shock Proteins; Ischemic Preconditioning; Male; MAP Kinase Signaling System; Molecular Sequence Data; Monoterpenes; Naloxone; Neuroprotective Agents; NF-kappa B; Potassium Channels; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; RGS Proteins | 2006 |
The macrophage beta-glucan receptor mediates arachidonate release induced by zymosan: essential role for Src family kinases.
Topics: Animals; Arachidonic Acid; beta-Glucans; Female; Lectins, C-Type; Macrophages; Membrane Proteins; Mice; Nerve Tissue Proteins; Phospholipase C gamma; Phosphorylation; Protein Kinase Inhibitors; Receptors, Immunologic; src-Family Kinases; Zymosan | 2007 |
In-vitro and in-vivo anti-inflammatory action of the ethanol extract of Trachelospermi caulis.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Carrageenan; Cell Line; Edema; Ethanol; Furans; Glucosides; Male; Mice; Mice, Inbred ICR; Nitric Oxide; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; Pain; Plant Extracts; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2007 |
5-LOX inhibitor modulates the inflammatory responses provoked by Helicobacter pylori infection.
Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Cell Line; Down-Regulation; Epithelial Cells; Glucosides; Helicobacter Infections; Helicobacter pylori; Humans; Hydrolyzable Tannins; Interleukin-8; Lipoxygenase Inhibitors; Macrophages; Masoprocol; Mitogen-Activated Protein Kinase 3; NF-kappa B; Oxidation-Reduction; Signal Transduction; Tumor Necrosis Factor-alpha | 2007 |
Regulation of endothelial cell migration by amphiphiles - are changes in cell membrane physical properties involved?
Topics: Animals; Arachidonic Acid; Cell Culture Techniques; Cell Membrane; Cell Movement; Docosahexaenoic Acids; Endothelial Cells; Glucosides; Lipid Bilayers; Lysophospholipids; Membrane Fluidity; Membrane Lipids; Octoxynol; Surface-Active Agents; Swine | 2007 |
A novel lipid binding site formed by the MAP kinase insert in p38 alpha.
Topics: Arachidonic Acid; Binding Sites; Chromatography, Gel; Computer Simulation; Crystallography, X-Ray; Detergents; Enzyme Activation; Glucosides; Humans; Isoenzymes; Kinetics; Models, Chemical; Models, Molecular; Mutation; Oxidation-Reduction; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Binding; Protein Conformation; Protein Structure, Secondary; Spectrum Analysis, Raman; Surface Plasmon Resonance | 2008 |
On the importance of plasmalogen status in stimulated arachidonic acid release in the macrophage cell line RAW 264.7.
Topics: Animals; Arachidonic Acid; Cell Line; Macrophages; Mice; Naphthalenes; Phospholipase A2 Inhibitors; Plasmalogens; Pyrones; Zymosan | 2008 |
Costimulation of dectin-1 and DC-SIGN triggers the arachidonic acid cascade in human monocyte-derived dendritic cells.
Topics: Arachidonic Acid; Cell Adhesion Molecules; Cell Line; Cyclooxygenase 2; Dendritic Cells; Humans; Intracellular Signaling Peptides and Proteins; Lectins, C-Type; Membrane Proteins; Monocytes; Nerve Tissue Proteins; Protein-Tyrosine Kinases; Receptors, Cell Surface; Syk Kinase; Zymosan | 2008 |
Regulation of cytosolic phospholipase A2alpha by hsp90 and a p54 kinase in okadaic acid-stimulated macrophages.
Topics: Animals; Arachidonic Acid; Benzoquinones; Calcimycin; Calcium; Carcinogens; Cytosol; Enzyme Activation; Enzyme Inhibitors; Female; Golgi Apparatus; Green Fluorescent Proteins; Group IV Phospholipases A2; HSP90 Heat-Shock Proteins; Immunoblotting; Immunoprecipitation; Ionophores; Lactams, Macrocyclic; Macrophages, Peritoneal; Mice; Mice, Inbred ICR; Mitogen-Activated Protein Kinase 10; NIH 3T3 Cells; Okadaic Acid; Phosphoamino Acids; Phosphorylation; Protein Transport; Rifabutin; Signal Transduction; Tetradecanoylphorbol Acetate; Zymosan | 2008 |
Cyclooxygenase-2 induced by zymosan in human monocyte-derived dendritic cells shows high stability, and its expression is enhanced by atorvastatin.
Topics: Antigens, CD; Arachidonic Acid; Atorvastatin; Cycloheximide; Cyclooxygenase 1; Cyclooxygenase 2; Dendritic Cells; Dinoprostone; Gene Expression; Half-Life; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kinetics; Mevalonic Acid; Peptidoglycan; Phospholipases A2, Cytosolic; Pyrroles; Zymosan | 2009 |
Signaling role for lysophosphatidylcholine acyltransferase 3 in receptor-regulated arachidonic acid reacylation reactions in human monocytes.
Topics: 1-Acylglycerophosphocholine O-Acyltransferase; Acylation; Arachidonic Acid; Cells, Cultured; Humans; Monocytes; Phospholipids; Signal Transduction; Zymosan | 2010 |
The 5-lipoxygenase inhibitor, zileuton, suppresses prostaglandin biosynthesis by inhibition of arachidonic acid release in macrophages.
Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Carrageenan; Cyclooxygenase 2; Dinoprostone; Disease Models, Animal; Humans; Hydroxyurea; Interferon-gamma; Intramolecular Oxidoreductases; Lipopolysaccharides; Lipoxygenase Inhibitors; Macrophages; Mice; Mice, Inbred Strains; Pleurisy; Prostaglandin-E Synthases; Prostaglandins F; Rats; Rats, Wistar; Zymosan | 2010 |
Prostaglandin E₂ production in mice is reduced by consumption of range-fed sources of red meat.
Topics: Animal Feed; Animal Husbandry; Animals; Arachidonic Acid; Cattle; Chickens; Diet; Dinoprostone; Edible Grain; Epoprostenol; Inflammation; Macrophages; Male; Meat; Mice; Mice, Inbred Strains; Peritoneum; Poaceae; Zymosan | 2011 |
Phospholipid sources for adrenic acid mobilization in RAW 264.7 macrophages. Comparison with arachidonic acid.
Topics: Animals; Arachidonic Acid; Cells, Cultured; Erucic Acids; Fatty Acids, Unsaturated; Gas Chromatography-Mass Spectrometry; Macrophages; Mice; Phosphatidylcholines; Phosphatidylinositols; Phospholipids; Zymosan | 2012 |
The response of human macrophages to β-glucans depends on the inflammatory milieu.
Topics: Adaptor Proteins, Signal Transducing; Animals; Arachidonic Acid; beta-Glucans; Cyclooxygenase 2; Cytokines; Dendritic Cells; Dinoprostone; Enzyme Activation; Gene Deletion; Humans; Inflammation; Lectins, C-Type; Macrophages; Mice; Mice, Knockout; NF-kappa B; Phosphorylation; Zymosan | 2013 |
Cytosolic group IVA and calcium-independent group VIA phospholipase A2s act on distinct phospholipid pools in zymosan-stimulated mouse peritoneal macrophages.
Topics: Animals; Arachidonic Acid; Calcium; Cells, Cultured; Cytosol; Group IV Phospholipases A2; Group VI Phospholipases A2; Macrophages, Peritoneal; Male; Mice; Zymosan | 2014 |
Inhibitory effect of acteoside on melittin-induced catecholamine exocytosis through inhibition of Ca(2+)-dependent phospholipase A2 and extracellular Ca(2+) influx in PC12 cells.
Topics: Animals; Arachidonic Acid; Calcium; Calcium Channels; Catecholamines; Chromogranin A; Dose-Response Relationship, Drug; Exocytosis; Glucosides; Melitten; PC12 Cells; Phenols; Phospholipases A2; Rats | 2015 |
Competition and allostery govern substrate selectivity of cyclooxygenase-2.
Topics: Algorithms; Allosteric Regulation; Allosteric Site; Animals; Arachidonic Acid; Arachidonic Acids; Binding, Competitive; Catalytic Domain; Cell Line; Computer Simulation; Cyclooxygenase 2; Endocannabinoids; Glycerides; Kinetics; Macrophages; Mice; Oxidation-Reduction; Prostaglandins; Protein Binding; Protein Multimerization; Sf9 Cells; Spodoptera; Substrate Specificity; Zymosan | 2015 |
The hallucinogenic diterpene salvinorin A inhibits leukotriene synthesis in experimental models of inflammation.
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Diterpenes; Diterpenes, Clerodane; Hallucinogens; Inflammation; Leukotriene Antagonists; Leukotriene B4; Macrophages, Peritoneal; Mice; Models, Theoretical; Rats; Rats, Wistar; Zymosan | 2016 |
Inhibitory effects of luteolin‑4'‑O‑β‑D‑glucopyranoside on P2Y12 and thromboxane A2 receptor‑mediated amplification of platelet activation in vitro.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Animals; Arachidonic Acid; Bridged Bicyclo Compounds, Heterocyclic; Fatty Acids, Unsaturated; Female; Glucosides; Glycogen Synthase Kinase 3 beta; Hydrazines; Luteolin; Phosphatidylinositol 3-Kinases; Platelet Activation; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Proto-Oncogene Proteins c-akt; Rats, Sprague-Dawley; Receptors, Purinergic P2Y12; Receptors, Thromboxane A2, Prostaglandin H2; rhoA GTP-Binding Protein; Serotonin; Signal Transduction; Thromboxane A2; Tritium | 2018 |
Frontline Science: Reprogramming COX-2, 5-LOX, and CYP4A-mediated arachidonic acid metabolism in macrophages by salidroside alleviates gouty arthritis.
Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Arthritis, Gouty; Cell Movement; Cell Polarity; Chondrocytes; Crystallization; Cyclooxygenase 2; Cytochrome P-450 CYP4A; Disease Models, Animal; Down-Regulation; Glucosides; Interleukin-1beta; Macrophages; Male; Mice; Models, Biological; Neutrophils; NF-kappa B; Phenols; Phenotype; Rabbits; Rats, Wistar; RAW 264.7 Cells; Signal Transduction; STAT1 Transcription Factor; Synovial Fluid; Tumor Necrosis Factor-alpha; Uric Acid | 2019 |
Cellular Plasmalogen Content Does Not Influence Arachidonic Acid Levels or Distribution in Macrophages: A Role for Cytosolic Phospholipase A
Topics: Animals; Arachidonic Acid; Cell Line; Gene Knockdown Techniques; Group IV Phospholipases A2; Lipidomics; Macrophages; Mass Spectrometry; Mice; Phospholipids; Plasmalogens; RAW 264.7 Cells; Zymosan | 2019 |
Anti-Inflammatory and Proresolving Effects of the Omega-6 Polyunsaturated Fatty Acid Adrenic Acid.
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arthritis, Experimental; Cells, Cultured; Fatty Acids, Omega-6; Fatty Acids, Unsaturated; Humans; Leukotriene B4; Lipidomics; Macrophages; Male; Mice; Mice, Transgenic; Neutrophils; Peritoneal Lavage; Peritonitis; Primary Cell Culture; THP-1 Cells; Zymosan | 2020 |
Myeloid-Specific Deficiency of
Topics: Animals; Arachidonic Acid; Coenzyme A Ligases; Inflammation; Mice; Mice, Transgenic; Phospholipids; Zymosan | 2021 |
Differential Mobilization of the Phospholipid and Triacylglycerol Pools of Arachidonic Acid in Murine Macrophages.
Topics: Animals; Arachidonic Acid; Macrophages; Mice; Phospholipids; Triglycerides; Zymosan | 2022 |