Compounds > glucose, (beta-d)-isomer
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glucose, (beta-d)-isomer and 2,3,5,4'-tetrahydroxystilbene 2-o-glucopyranoside

glucose, (beta-d)-isomer has been researched along with 2,3,5,4'-tetrahydroxystilbene 2-o-glucopyranoside in 123 studies

Research

Studies (123)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (0.81)18.2507
2000's18 (14.63)29.6817
2010's87 (70.73)24.3611
2020's17 (13.82)2.80

Authors

AuthorsStudies
Duck, CC; Grech, JN; Li, Q; Roufogalis, BD1
Kimura, Y; Okuda, H1
Sun, YK; Zhang, XQ; Zhao, HP1
Bai, HB; Long, J; Wang, JF1
Jiang, FX; Li, XX; Liu, EB; Ren, RF; Wei, HQ; Zhao, XL1
Wang, DQ; Wang, W1
Liu, Q; Tang, L; Wang, J; Xu, J; Ye, S1
Ai, HX; Li, L; Wei, HF; Xing, Y; Ye, CF; Zhang, L1
Fang, L; Feng, B; Li, L; Tang, Y; Wang, R; Ye, C; Zhang, L1
Li, F; Wang, CH; Zhang, W; Zhu, WZ1
Guan, S; Li, P; Su, W; Wang, N; Wang, Y1
Li, F; Shen, Y; Wang, CH; Wang, YQ; Zhang, W2
Dang, Z; Liu, B; Pu, YT; Wen, Z; You, XK; Zheng, ZK1
Chen, JG; Dong, LD; Gu, J; Wang, F; Wang, T; Wu, PF; Wu, WN; Xiong, Z; Yang, YJ1
Wang, CH; Wang, YQ; Xu, XL; Zhang, W; Zhu, WZ1
He, G; Jiang, Z; Long, M; Tu, Z; Xu, J; Yang, G1
Wang, JL; Wang, WQ; Zhang, SH1
Fu, XF; Luo, HB; Shi, XQ; Yang, JS; Yang, QD1
Ho, CT; Huang, D; Lv, L; Sang, S; Shao, X; Wang, L1
Yang, J; Yang, Q; Zeng, J; Zheng, L; Zhou, Z1
Cai, L; Qu, X; Zhang, Q; Zhong, G1
Cai, F; Jia, Y; Li, C; Li, J; Liu, Q; Tang, J; Wang, C; Yang, Y; Zhao, X1
Chen, HB; Liang, ZT; Shi, YX; Zhao, ZZ1
Chen, JG; Fu, H; Hu, ZL; Long, LH; Wang, F; Wang, T; Wang, W; Wu, PF; Xie, N; Yang, YJ1
Yang, J; Yang, QD; Zeng, J; Zheng, LJ; Zhou, ZW1
Li, F; Shen, Y; Wang, CH; Xu, XL; Zhang, W1
Chen, J; Kang, X; Li, G; Li, X; Li, Y; Qin, R; Sun, J; Tao, L1
Ou-Yang, HZ; Qi, AD; Ren, XL; Wang, GF; Wang, M1
Chen, XF; Huang, YJ; Wang, YQ; Xu, XL; Zhang, W1
Li, L; Sun, FL; Zhang, L; Zhang, RY1
Chen, S; Gu, H; Lou, Z; Lv, G; Shan, L1
Chang, MJ; Wang, JL; Xiao, JH; Zeng, C1
Du, X; Hou, Y; Li, M; Li, Z; Yang, Q; Yuan, M; Zhou, L; Zhou, Z1
Chen, XF; Huang, YJ; Lin, DY; Xu, XL; Zhang, W1
Bao, YJ; Chen, QQ; Chen, XF; Huang, YJ; Zhang, W; Zhu, W1
Cui, TB; Liu, ZY; Shao, L; Zhao, SJ; Zhao, W1
Chen, JZ; Chen, S; Fan, J; Fan, JZ; He, QZ; Liu, J; Luo, ZJ; Meng, GL; Yang, L; Zhang, JK1
Duan, J; Gan, W; Han, X; Ling, S; Sun, L; Xu, JW1
Li, L; Li, Y; Xing, Y; Yu, S; Zhang, L; Zhang, R1
Fan, WJ; Ling, DY; Xu, XL; Zhang, W; Zhu, QY1
Chen, X; Fan, W; Huang, C; Yao, W; Zhang, W; Zhong, H1
Chang, MJ; Wang, JL; Wang, Y; Xiao, JH; Yan, YL; Yang, J1
Bai, X; Chen, DQ; Du, X; Feng, YL; Lin, RC; Xi, ZH; Zhang, L; Zhao, YY1
Horng, LY; Hsu, PL; Peng, KY; Sung, HC; Wu, CL; Wu, RT1
Chang, YX; Gao, XM; He, J; Li, J; Ma, WF; Zhang, BL; Zhang, L; Zhang, P; Zheng, F1
Li, BH; Song, LJ; Wu, JD; Zeng, QL; Zhao, WC1
Chen, J; Chen, L; Hao, D; Huang, L; Zhang, L1
Chen, X; Huang, C; Wang, J; Wang, Y; Yao, W; Zhang, W1
Da, XW; Hao, HZ; He, AD; Liu, G; Ming, ZY; Wang, JL; Xiang, JZ; Xiang, K; Yin, Z; Zhou, YJ1
Liu, J; Lu, YF; Shi, JS; Wang, YY; Yang, J; Zhang, F1
Hu, YE; Wang, F; Xu, XL; Zhang, W; Zhao, C; Zhou, ZY; Zhu, QY1
Gu, W; He, Y; Li, Y; Lin, P; Sun, R; Wang, W; Yu, J; Zhao, R1
Liu, TY; Qin, XY; Yang, XP; Yu, LC1
Lei, L; Li, J; Sheng, S; Xia, W; Zhao, S; Zhao, W1
Huang, YJ; Ling, DY; Xu, XL; Zhang, W1
Huang, C; Jing, X; Sun, Q; Wang, H; Yao, W; Zhang, W1
Lin, FQ; Liu, H; Shi, JS; Wang, YY; Yang, J; Zhang, F1
Nian, L; Song, F; Wang, S; Xu, S; Zhao, J; Zhou, X1
Kaji, K; Koshibe, Y; Shirataki, Y; Tamura, M; Ueda, JY1
Ho, HO; Hsieh, CM; Jhan, HJ; Sheu, MT; Wang, CJ1
Gu, C; Jing, X; Meng, G; Shao, H; Wang, H; Yao, W; Zhang, W1
Cao, W; Hu, J; Qiu, P; Sun, J; Wang, S; Xie, Y; Yang, Q; Zhou, X1
Dong, LH; Guo, PP; Wang, CY; Yan, WY; Zhang, ZJ1
Hua, F; Nian, L; Song, F; Sun, JY; Tang, HF; Wang, SW; Xie, YH; Yang, Q; Zhao, J; Zhou, XX1
Büchter, C; Fritz, G; Havermann, S; Honnen, S; Proksch, P; Wätjen, W; Zhao, L1
Chen, LW; Horng, LY; Hsu, KT; Hsu, PL; Tseng, WZ; Wu, CL; Wu, RT1
Lin, F; Shi, W; Wan, Y; Zhang, F; Zhang, Z; Zhou, Y1
Li, L; Li, YL; Shen, C; Sun, FL; Zhang, L; Zhang, RY1
Gu, W; Lin, P; Lu, J; Wang, Y; Yu, J; Zhao, R1
Chen, J; Chen, L; He, H; Tang, H; Tian, J; Wang, S; Zhang, W; Zhang, X; Zhao, J1
Liang, Y; Nian, L; Song, F; Wang, S; Xu, S; Zhao, J; Zhou, X1
Chen, JG; Chen, T; Li, YK; Liu, J; Long, LH; Wang, F; Wu, PF; Yang, YJ1
Hsieh, SL; Huang, GC; Jeng, JH; Lee, CT; Leung, W; Lin, CL; Wu, CC1
Duan, W; Hua, F; Li, H; Song, F; Sun, J; Wang, S; Xie, Y; Yan, L; Yang, Q; Zhou, X1
Kim, YM; Nguyen, MC; Ryoo, S; Won, MH; Yi, B1
Ling, S; Xu, JW1
Huang, L; Meng, G; Sun, Q; Tang, L; Xu, X; Yang, L; Yao, W; Zhang, W1
Huang, XL; Peng, Y; Xu, J; Xu, XL; Zeng, Y; Zhang, W1
Choi, YW; Jin, ML; Park, G; Park, SY; Wang, Z1
Chen, BB; Chen, GT; Song, Y; Yang, M; Zhang, W; Zhang, Y1
Duan, J; Ling, S; Ni, R; Xu, JW1
Kang, J; Li, F; Mu, Y; Wang, S; Xie, Y; Xu, Z; Yang, Q; Zhang, H; Zhang, Y; Zhou, X1
Chen, X; Hu, W; Huang, C; Jiang, B; Lu, X; Wang, J; Zhang, W1
Duan, WX; Jin, ZX; Li, BY; Song, F; Wang, SW; Yan, L; Yang, Q; Yu, LM; Zhai, ME; Zhang, B; Zhang, M; Zhao, H; Zhou, XX1
Chen, X; Chen, Z; Gong, Y; Hu, W; Huang, C; Tong, L; Wang, P; Wu, J; Xu, X; Yao, W; Zhang, W1
Fan, YX; Jiang, LL; Li, HJ; Li, P; Luo, N; Ma, J; Yu, Q1
Cheng, GY; Chin, YT; Chiu, HC; Fu, E; Lai, HY; Lee, SY; Lin, CY; Lin, HY; Lin, SJ; Liu, LF; Shih, YJ; Tang, HY; Whang-Peng, J1
Chen, X; Peng, Y; Tang, K; Xu, X1
Wang, C; Wang, X; Xu, M; Zhang, L; Zhao, J; Zhu, M1
Bayarsengee, U; Cheng, CW; Chiang, YH; Lin, EY; Wang, CC1
Chen, C; Li, L; Xu, T; Yin, X; Zhang, L1
Fang, K; Li, W; Long, H; Luo, K; Ma, J; Sun, R; Xie, Y; Xu, B; Zhou, S1
Chen, LG; Lee, CJ; Lee, YH; Tsai, PW; Wang, CC1
Chen, L; Gu, X; Huang, J; Li, F; Sun, C; Wang, CZ; Yao, D; Yuan, CS; Zhang, L; Zhang, Y1
Li, Y; Liu, D; Ning, Z; Owoicho Orgah, J; Wang, Y; Zhu, J; Zhu, Y1
Chang, Y; Chen, Y; Du, KZ; He, J; Li, J; Tang, G; Tian, F1
Deng, YR; Liu, YN; Ren, XL; Sun, LL; Wang, M; You, GJ; Zhang, HJ1
Hong, SG; Hwang, YH; Kang, KY; Kim, KJ; Kim, SJ; Mun, SK; Son, YJ; Yee, ST1
Chen, J; Zhang, L1
Hwang, YH; Kim, H; Kim, SJ; Yee, ST1
Ding, Z; Pan, H; Shen, H; Shen, J; Xu, L; Yuan, L; Zhang, Y1
Deng, J; Gao, Y; Gong, Q; Hu, A; Huang, J; Li, L; Li, S; Liu, J; Wu, L; Xu, S1
Chan, YH; Chin, YT; Hsiung, CN; Huang, HM; Kuo, PJ; Lee, HW; Lee, SY; Lin, CY; Lin, HY; Weng, IT1
Hua, YQ; Peng, Y; Xu, J; Xu, XL; Zeng, Y1
Gu, RZ; Lan, R; Lang, XY; Li, XX; Liu, QS; Qin, XY; Yu, Y1
Gu, W; He, Y; Li, F; Yang, X; Yu, J; Zhang, T; Zhao, R1
Gao, J; He, C; Li, P; Li, W; Liu, Q; Niu, M; Peng, S; Qi, Y; Tong, J; Wang, D; Wang, J; Yuan, T; Zhang, L; Zhang, Z; Zhao, X1
Hai, C; Li, W; Liu, J; Liu, R; Wang, X; Wang, Z; Yu, W; Zhao, J; Zheng, Y; Zhu, J1
Gong, X; Li, Y; Wang, C; Zheng, L; Zhou, Y1
Dai, C; Dong, L; Hou, M; Qian, J; Sun, J; Wu, X1
Jiang, CY; Lan, R; Lang, XY; Li, XX; Qin, XY; Yu, Y1
Dai, XY; Gong, LH; Hu, NH; Li, YX; Peng, C; Wang, C; Yu, LY1
Chen, J; Feng, Y; Guo, H; Li, J; Wang, N; Wang, X; Zeng, J; Zhang, M1
Hsu, CJ; Lin, JN; Tseng, GF; Wen, YH; Wu, HP; Wu, RS; Yu, SH1
Bi, Q; Gu, W; Liang, L; Meng, F; Yang, M; Yang, X; Yu, J; Zeng, L; Zhang, T1
Chin, YT; Hsiung, CN; Huang, HM; Kuo, PJ; Lee, SY; Lin, CY; Lin, HY; Tsai, MS; Weng, IT; Wu, Y1
Dai, B; Liu, MJ; Tang, L; Wang, L; Xiao, WZ; Xing, W; Yang, L1
Fan, SR; Lan, R; Lang, XY; Qin, XY; Ren, TT; Yu, Y1
He, X; Liu, J; Liu, M; Long, G; Xia, XH1
Chang, CS; Chang, YY; Hsiao, LC; Lin, HJ; Lin, YF; Liu, DZ1
Hsu, CJ; Hwang, CF; Lin, CC; Lin, HY; Lin, JN; Tseng, GF; Wen, YH; Wu, HP1
Bai, J; Gong, L; Huang, J; Huang, S; Huang, Z; Liang, Y; Qiu, X; Su, H; Xu, W; Zhang, J1

Reviews

6 review(s) available for glucose, (beta-d)-isomer and 2,3,5,4'-tetrahydroxystilbene 2-o-glucopyranoside

ArticleYear
[Progress of study on brain protective effect and mechanism of Polygonum multiflorum].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2005, Volume: 25, Issue:10

    Topics: Animals; Antioxidants; Calcium Channel Blockers; Drugs, Chinese Herbal; Glucosides; Humans; Learning Disabilities; Neuroprotective Agents; Plant Extracts; Polygonum; Stilbenes

2005
Biological Activities of 2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-Glucoside in Antiaging and Antiaging-Related Disease Treatments.
    Oxidative medicine and cellular longevity, 2016, Volume: 2016

    Topics: Aging; Animals; Cardiovascular Agents; Cellular Senescence; Disease Models, Animal; Drugs, Chinese Herbal; Fallopia multiflora; Gene Expression Regulation; Glucosides; Humans; Hypoglycemic Agents; Neuroprotective Agents; Phytotherapy; Plants, Medicinal; Signal Transduction; Stilbenes

2016
Current pharmacological developments in 2,3,4',5-tetrahydroxystilbene 2-O-β-D-glucoside (TSG).
    European journal of pharmacology, 2017, Sep-15, Volume: 811

    Topics: Aging; Animals; Cardiovascular System; Central Nervous System; Glucosides; Humans; Stilbenes

2017
Therapeutic applications of resveratrol and its derivatives on periodontitis.
    Annals of the New York Academy of Sciences, 2017, Volume: 1403, Issue:1

    Topics: Anti-Inflammatory Agents; Fibroblasts; Glucosides; Humans; Periodontitis; Porphyromonas gingivalis; Resveratrol; Stilbenes; Treatment Outcome

2017
Biological Effects of Tetrahydroxystilbene Glucoside: An Active Component of a Rhizome Extracted from
    Oxidative medicine and cellular longevity, 2018, Volume: 2018

    Topics: Animals; Antioxidants; Biological Products; Cytoprotection; Glucosides; Humans; Plant Extracts; Polygonum; Rhizome; Stilbenes

2018
A review on the extraction, purification, detection, and pharmacological effects of 2,3,5,4'-tetrahydroxystilbene-2-O-β-d-glucoside from Polygonum multiflorum.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020, Volume: 124

    Topics: Animals; Fallopia multiflora; Glucosides; Humans; Medicine, Chinese Traditional; Stilbenes

2020

Other Studies

117 other study(ies) available for glucose, (beta-d)-isomer and 2,3,5,4'-tetrahydroxystilbene 2-o-glucopyranoside

ArticleYear
Novel Ca(2+)-ATPase inhibitors from the dried root tubers of Polygonum Multiflorum.
    Journal of natural products, 1994, Volume: 57, Issue:12

    Topics: Australia; Benzofurans; Ca(2+) Mg(2+)-ATPase; Calcium-Transporting ATPases; Erythrocytes; Glucosides; Humans; In Vitro Techniques; Plant Roots; Plants, Medicinal; Stilbenes

1994
Effects of naturally occurring stilbene glucosides from medicinal plants and wine, on tumour growth and lung metastasis in Lewis lung carcinoma-bearing mice.
    The Journal of pharmacy and pharmacology, 2000, Volume: 52, Issue:10

    Topics: Animals; Antineoplastic Agents; Carcinoma, Lewis Lung; Cattle; DNA; Drug Screening Assays, Antitumor; Endothelium, Vascular; Female; Glucosides; Humans; Mice; Mice, Inbred C57BL; Organ Size; Phytotherapy; Plants, Medicinal; Resveratrol; Ribonucleotide Reductases; Spleen; Stilbenes; Swine; T-Lymphocytes; Thymus Gland; Umbilical Veins; Wine

2000
[Determination of 2,3,5,4'-tetrahydroxystilbene-2-O-beta-D-glucoside in yangan oral liquid by HPLC].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2003, Volume: 28, Issue:2

    Topics: Chromatography, High Pressure Liquid; Drug Combinations; Drugs, Chinese Herbal; Glucosides; Plants, Medicinal; Polygonum; Quality Control; Stilbenes

2003
[Study on optimizing extraction process of root of Polygonum multiflorum].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2004, Volume: 29, Issue:3

    Topics: Antioxidants; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Ethanol; Glucosides; Plant Roots; Plants, Medicinal; Polygonum; Stilbenes; Technology, Pharmaceutical; Time Factors

2004
[Determination of 2,3,5,4'-tetrahydroxystilbene-2-O-beta-D-glucoside in the traditional Chinese preparation by high performance liquid chromatography with chemiluminescence detection].
    Guang pu xue yu guang pu fen xi = Guang pu, 2005, Volume: 25, Issue:6

    Topics: Capsules; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Formaldehyde; Glucosides; Kinetics; Luminescence; Luminescent Measurements; Molecular Structure; Nitric Acid; Reproducibility of Results; Stilbenes; Tablets

2005
Postconditioning's protection of THSG on cardiac ischemia-reperfusion injury and mechanism.
    Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 2006, Volume: 26, Issue:1

    Topics: Animals; Antioxidants; Female; Glucosides; Ischemic Preconditioning, Myocardial; Male; Polygonum; Random Allocation; Rats; Rats, Wistar; Reperfusion Injury; Stilbenes

2006
Learning-memory deficit with aging in APP transgenic mice of Alzheimer's disease and intervention by using tetrahydroxystilbene glucoside.
    Behavioural brain research, 2006, Oct-16, Volume: 173, Issue:2

    Topics: Age Factors; Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Analysis of Variance; Animals; Disease Models, Animal; Glucosides; Learning Disabilities; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Pattern Recognition, Visual; Stilbenes

2006
Changes in hippocampal synapses and learning-memory abilities in age-increasing rats and effects of tetrahydroxystilbene glucoside in aged rats.
    Neuroscience, 2007, Nov-23, Volume: 149, Issue:4

    Topics: Age Factors; Aging; Analysis of Variance; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation, Developmental; Glucosides; Hippocampus; Learning; Male; Maze Learning; Microscopy, Electron, Transmission; Rats; Rats, Sprague-Dawley; Stilbenes; Synapses; Synaptophysin; Time Factors

2007
2,3,4',5-Tetrahydroxystilbene-2-O-beta-D-glucoside suppresses matrix metalloproteinase expression and inflammation in atherosclerotic rats.
    Clinical and experimental pharmacology & physiology, 2008, Volume: 35, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Atherosclerosis; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Glucosides; Inflammation; Male; Matrix Metalloproteinases; Rats; Rats, Sprague-Dawley; Simvastatin; Stilbenes

2008
A potent tyrosinase activator from Radix Polygoni multiflori and its melanogenesis stimulatory effect in B16 melanoma cells.
    Phytotherapy research : PTR, 2008, Volume: 22, Issue:5

    Topics: Animals; Anthraquinones; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Enzyme Activation; Glucosides; Melanins; Melanoma, Experimental; Mice; Monophenol Monooxygenase; Plant Extracts; Polygonum; Stilbenes

2008
[Effects of 2, 3, 4', 5-tetrahydroxystilbene -2-O-beta-D glucoside on content of nitric oxide synthase and expression of nitric oxide synthase in artery vessels of experimental atherosclerotic rats].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2008, Volume: 33, Issue:8

    Topics: Animals; Arteries; Atherosclerosis; Gene Expression Regulation, Enzymologic; Glucosides; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Rats; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes

2008
[Harmful elements removal from Polygonum multiflorum by supercritical CO2 extraction].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2008, Volume: 31, Issue:10

    Topics: Arsenic; Carbon Dioxide; Chromatography, Supercritical Fluid; Copper; Drugs, Chinese Herbal; Glucosides; Lead; Plants, Medicinal; Polygonaceae; Pressure; Stilbenes; Technology, Pharmaceutical; Temperature

2008
Protection by tetrahydroxystilbene glucoside against cerebral ischemia: involvement of JNK, SIRT1, and NF-kappaB pathways and inhibition of intracellular ROS/RNS generation.
    Free radical biology & medicine, 2009, Aug-01, Volume: 47, Issue:3

    Topics: Animals; Antioxidants; Apoptosis; Brain; Cells, Cultured; Cytoprotection; Down-Regulation; Drugs, Chinese Herbal; Glucosides; Infarction, Middle Cerebral Artery; MAP Kinase Kinase 4; Membrane Potential, Mitochondrial; Mitochondria; NF-kappa B; Nitric Oxide Synthase Type II; Polygonum; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Reactive Nitrogen Species; Reactive Oxygen Species; Rhizome; Signal Transduction; Sirtuin 1; Stilbenes

2009
Effects of 2,3,4',5-tetrahydroxystilbene 2-O-beta-D-glucoside on vascular endothelial dysfunction in atherogenic-diet rats.
    Planta medica, 2009, Volume: 75, Issue:11

    Topics: Animals; Aorta; Atherosclerosis; Disease Models, Animal; Drugs, Chinese Herbal; Endothelium, Vascular; Glucosides; Male; Microscopy, Electron, Transmission; Nitrates; Nitric Oxide Synthase; Nitrites; Polygonum; Rats; Rats, Sprague-Dawley; RNA, Messenger; Stilbenes

2009
2, 3, 5, 4'-tetrahydroxystilbene-2-O-beta-D-glucoside (THSG) induces melanogenesis in B16 cells by MAP kinase activation and tyrosinase upregulation.
    Life sciences, 2009, Aug-26, Volume: 85, Issue:9-10

    Topics: Animals; Antioxidants; Cell Line, Tumor; Enzyme Activation; Glucosides; Hair Color; Melanins; Melanoma, Experimental; Mice; Monophenol Monooxygenase; p38 Mitogen-Activated Protein Kinases; Skin Pigmentation; Stilbenes; Up-Regulation

2009
Protective effect of tetrahydroxystilbene glucoside on cardiotoxicity induced by doxorubicin in vitro and in vivo.
    Acta pharmacologica Sinica, 2009, Volume: 30, Issue:11

    Topics: Animals; Animals, Newborn; Antibiotics, Antineoplastic; Apoptosis; Calcium; Cardiotonic Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Doxorubicin; Glucosides; Heart Diseases; Male; Mice; Myocytes, Cardiac; Rats; Reactive Oxygen Species; Signal Transduction; Stilbenes

2009
Tetrahydroxy stilbene glucoside reduces the cognitive impairment and overexpression of amyloid precursor protein induced by aluminum exposure.
    Neuroscience bulletin, 2009, Volume: 25, Issue:6

    Topics: Aluminum Chloride; Aluminum Compounds; Amyloid beta-Protein Precursor; Animals; Avoidance Learning; Blotting, Western; Chlorides; Cognition Disorders; Glucosides; Hippocampus; Male; Neuroprotective Agents; Neuropsychological Tests; Random Allocation; Rats; Rats, Sprague-Dawley; Stilbenes; Time Factors; Vitamin E; Vitamins

2009
Stilbene glucoside from Polygonum multiflorum Thunb.: a novel natural inhibitor of advanced glycation end product formation by trapping of methylglyoxal.
    Journal of agricultural and food chemistry, 2010, Feb-24, Volume: 58, Issue:4

    Topics: Chromatography, Liquid; Diabetes Complications; Diabetes Mellitus; Glucosides; Glycation End Products, Advanced; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Models, Molecular; Molecular Conformation; Polygonum; Pyruvaldehyde; Resveratrol; Stilbenes

2010
[Neuroprotective mechanism of tetrahydroxystilbene glucoside on rats after cerebral ischemia-reperfusion].
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2010, Volume: 35, Issue:4

    Topics: Animals; GAP-43 Protein; Glucosides; Infarction, Middle Cerebral Artery; Male; Nerve Growth Factor; Neuroprotective Agents; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Stilbenes

2010
[Determination of 2,3,5,4'-tetrahydroxystilbene-2-O-beta-D-glucopyranoside and anthraquinon simultaneously in Polygonum multiflori of different growing stage and gathering periods by HPLC].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2010, Volume: 35, Issue:10

    Topics: Anthraquinones; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Glucosides; Polygonum; Stilbenes

2010
Tetrahydroxystilbene glucoside ameliorates diabetic nephropathy in rats: involvement of SIRT1 and TGF-β1 pathway.
    European journal of pharmacology, 2010, Dec-15, Volume: 649, Issue:1-3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Biomarkers; Cell Line; Cyclooxygenase 2; Diabetic Nephropathies; Dose-Response Relationship, Drug; Glucosides; Histone Deacetylase Inhibitors; Hyperglycemia; Kidney Cortex; Male; Mesangial Cells; Oxidative Stress; Random Allocation; Rats; Rats, Sprague-Dawley; Signal Transduction; Sirtuin 1; Stilbenes; Transforming Growth Factor beta1

2010
Histochemical analysis of the root tuber of Polygonum multiflorum Thunb. (Fam. Polygonaceae).
    Microscopy research and technique, 2011, Volume: 74, Issue:6

    Topics: Anthraquinones; Chromatography, High Pressure Liquid; Glucosides; Histocytochemistry; Mass Spectrometry; Microscopy, Fluorescence; Polygonum; Root Nodules, Plant; Stilbenes

2011
Tetrahydroxystilbene glucoside, a plant-derived cognitive enhancer, promotes hippocampal synaptic plasticity.
    European journal of pharmacology, 2011, Jan-10, Volume: 650, Issue:1

    Topics: Animals; CA1 Region, Hippocampal; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Differentiation; Cognition; Electric Stimulation; Enzyme Activation; Female; Glucosides; Hippocampus; In Vitro Techniques; Intracellular Space; Long-Term Potentiation; Male; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neuronal Plasticity; Neurons; PC12 Cells; Phosphorylation; Polygonum; Rats; Stilbenes; Synapses

2011
[Effects of tetrahydroxystilbene glucoside on nerve growth factor and growth associated protein in rats after cerebral ischemia-reperfusion].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2010, Volume: 33, Issue:7

    Topics: Animals; Brain Ischemia; Cerebral Cortex; Disease Models, Animal; GAP-43 Protein; Glucosides; Immunohistochemistry; Infarction, Middle Cerebral Artery; Male; Nerve Growth Factor; Neuroprotective Agents; Polygonaceae; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Stilbenes

2010
[The expression of matrix metalloproteinase-2,9 on atherosclerosis in experimental rats by treatment of 2,3,4',5-tetrahydroxystilbene -2-0-beta-D glucoside].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2009, Volume: 25, Issue:1

    Topics: Animals; Atherosclerosis; C-Reactive Protein; Glucosides; Interferon-alpha; Interleukin-6; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Polygonum; Rats; Rats, Sprague-Dawley; RNA, Messenger; Stilbenes

2009
Protection by tetrahydroxystilbene glucoside against neurotoxicity induced by MPP+: the involvement of PI3K/Akt pathway activation.
    Toxicology letters, 2011, Apr-10, Volume: 202, Issue:1

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Apoptosis; Glucosides; Herbicides; Nervous System; Neuroprotective Agents; PC12 Cells; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Signal Transduction; Stilbenes

2011
Kinetics and mechanism of 2,3,5,4'-tetrahydroxystilbene-2-O-β-d-glycoside (THSG) degradation in aqueous solutions.
    Journal of pharmaceutical and biomedical analysis, 2011, Apr-28, Volume: 55, Issue:1

    Topics: Chromatography, High Pressure Liquid; Drug Stability; Glucosides; Hot Temperature; Hydrogen-Ion Concentration; Hydrolysis; Hypolipidemic Agents; Isomerism; Kinetics; Light; Oxidation-Reduction; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Stilbenes

2011
2,3,4',5-Tetrahydroxystilbene-2-O-β-d-glucoside inhibits platelet-derived growth factor-induced proliferation of vascular smooth muscle cells by regulating the cell cycle.
    Clinical and experimental pharmacology & physiology, 2011, Volume: 38, Issue:5

    Topics: Animals; Becaplermin; Cardiovascular Agents; Cell Cycle; Cell Cycle Proteins; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Down-Regulation; Drug Evaluation, Preclinical; Gene Expression Regulation; Glucosides; Male; Models, Biological; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Rats; Rats, Sprague-Dawley; Stilbenes

2011
Tetrahydroxystilbene glucoside protects human neuroblastoma SH-SY5Y cells against MPP+-induced cytotoxicity.
    European journal of pharmacology, 2011, Jun-25, Volume: 660, Issue:2-3

    Topics: 1-Methyl-4-phenylpyridinium; bcl-2-Associated X Protein; Caspase 3; Cell Line, Tumor; Cell Membrane; Cell Survival; Cytoprotection; Gene Expression Regulation; Glucosides; Humans; Mitochondria; Neuroblastoma; Neuroprotective Agents; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Stilbenes

2011
Pharmacokinetic profile of 2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside in mice after oral administration of Polygonum multiflorum extract.
    Drug development and industrial pharmacy, 2012, Volume: 38, Issue:2

    Topics: Administration, Oral; Animals; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Drugs, Chinese Herbal; Glucosides; Male; Medicine, Chinese Traditional; Mice; Models, Animal; Plant Preparations; Plant Roots; Plants, Medicinal; Polygonum; Stilbenes

2012
Beneficial effects of THSG on acetic acid-induced experimental colitis: involvement of upregulation of PPAR-γ and inhibition of the Nf-Κb inflammatory pathway.
    Molecules (Basel, Switzerland), 2011, Oct-12, Volume: 16, Issue:10

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Drugs, Chinese Herbal; Glucosides; Interleukin-6; Male; Malondialdehyde; Mesalamine; Mice; NF-kappa B; PPAR gamma; Stilbenes; Tumor Necrosis Factor-alpha

2011
Tetrahydroxystilbene glucoside improves learning and (or) memory ability of aged rats and may be connected to the APP pathway.
    Canadian journal of physiology and pharmacology, 2011, Volume: 89, Issue:11

    Topics: Animals; Drug Administration Schedule; Drug Evaluation, Preclinical; Gene Expression Profiling; Glucosides; Hippocampus; Learning; Male; Maze Learning; Memory; Nootropic Agents; Rats; Rats, Sprague-Dawley; Software; Stilbenes; Time Factors

2011
2,3,4',5-tetrahydroxystilbene-2-O-β-D-glucoside inhibits proliferation of vascular smooth muscle cells: involvement of NO/cGMP/PKG pathway.
    Phytotherapy research : PTR, 2012, Volume: 26, Issue:7

    Topics: Animals; Becaplermin; Carbazoles; Cell Cycle; Cell Proliferation; Cells, Cultured; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Glucosides; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Polygonum; Proto-Oncogene Proteins c-sis; Quinoxalines; Rats; Rats, Sprague-Dawley; Signal Transduction; Stilbenes

2012
2,3,4',5-Tetrahydroxystilbene-2-O-β-D-glucoside inhibits angiotensin II-induced cardiac fibroblast proliferation via suppression of the reactive oxygen species-extracellular signal-regulated kinase 1/2 pathway.
    Clinical and experimental pharmacology & physiology, 2012, Volume: 39, Issue:5

    Topics: Angiotensin II; Animals; Animals, Newborn; Cell Proliferation; Cells, Cultured; Fibroblasts; Glucosides; Growth Inhibitors; MAP Kinase Signaling System; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Stilbenes

2012
2,3,5,4'- tetrahydroxystilbene-2-O-β-D-glycoside biosynthesis by suspension cells cultures of Polygonum multiflorum Thunb and production enhancement by methyl jasmonate and salicylic acid.
    Molecules (Basel, Switzerland), 2012, Feb-22, Volume: 17, Issue:2

    Topics: Acetates; Cell Culture Techniques; Cyclopentanes; Glucosides; Oxylipins; Plant Cells; Polygonum; Salicylic Acid; Stilbenes; Suspensions

2012
Protective effect of tetrahydroxystilbene glucoside against hydrogen peroxide-induced dysfunction and oxidative stress in osteoblastic MC3T3-E1 cells.
    European journal of pharmacology, 2012, Aug-15, Volume: 689, Issue:1-3

    Topics: 3T3 Cells; Animals; Cell Survival; Cytoprotection; Glucosides; Hydrogen Peroxide; Mice; Osteoblasts; Oxidative Stress; Stilbenes

2012
2,3,5,4'-tetrahydroxystilbene-2-O-β-d-glucoside ameliorates vascular senescence and improves blood flow involving a mechanism of p53 deacetylation.
    Atherosclerosis, 2012, Volume: 225, Issue:1

    Topics: Aging; Animals; Carotid Arteries; Cellular Senescence; Glucosides; Human Umbilical Vein Endothelial Cells; Humans; Male; Nitric Oxide Synthase Type III; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Regional Blood Flow; Sirtuin 1; Stilbenes; Tumor Suppressor Protein p53

2012
Tetrahydroxystilbene glucoside antagonizes age-related α-synuclein overexpression in the hippocampus of APP transgenic mouse model of Alzheimer's disease.
    Restorative neurology and neuroscience, 2013, Volume: 31, Issue:1

    Topics: Aging; alpha-Synuclein; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Blotting, Western; Brain Chemistry; Data Interpretation, Statistical; DNA, Complementary; Glucosides; Hippocampus; Humans; Immunohistochemistry; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microarray Analysis; Nootropic Agents; Real-Time Polymerase Chain Reaction; RNA, Messenger; Stilbenes

2013
The effect of 2,3,4',5-tetrahydroxystilbene-2-0-β-D glucoside on neointima formation in a rat artery balloon injury model and its possible mechanisms.
    European journal of pharmacology, 2013, Jan-05, Volume: 698, Issue:1-3

    Topics: Animals; Becaplermin; Carotid Arteries; Carotid Artery Injuries; Catheters; Cell Movement; Extracellular Matrix; Gene Expression Regulation; Glucosides; Hyperplasia; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Neointima; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-sis; Rats; Rats, Sprague-Dawley; Signal Transduction; Stilbenes

2013
Proteomic analysis for anti-atherosclerotic effect of tetrahydroxystilbene glucoside in rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2013, Volume: 67, Issue:2

    Topics: Animals; Annexin A1; Aorta; Apolipoprotein A-I; Apoptosis; Atherosclerosis; Calreticulin; Cell Adhesion; Cholesterol; Down-Regulation; Gene Expression Regulation; Glucosides; HSP70 Heat-Shock Proteins; Inflammation; Male; Proteome; Proteomics; Rats; Rats, Sprague-Dawley; Stilbenes; Up-Regulation; Vimentin

2013
2, 3, 5, 4'-Tetrahydroxystilbene-2-O-beta-D-glucoside improves gastrointestinal motility disorders in STZ-induced diabetic mice.
    PloS one, 2012, Volume: 7, Issue:12

    Topics: Animals; Caspase 3; Diabetes Mellitus, Experimental; Gastrointestinal Motility; Glucosides; Glutathione Peroxidase; Malondialdehyde; Mice; Nitric Oxide Synthase Type I; Oxidative Stress; Phosphorylation; Stilbenes; Streptozocin

2012
Pharmacokinetics of 2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside in rat using ultra-performance LC-quadrupole TOF-MS.
    Journal of separation science, 2013, Volume: 36, Issue:5

    Topics: Animals; Bile; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Feces; Glucosides; Male; Mass Spectrometry; Rats; Rats, Sprague-Dawley; Stilbenes; Tissue Distribution

2013
Activation of mitochondrial function and Hb expression in non-haematopoietic cells by an EPO inducer ameliorates ischaemic diseases in mice.
    British journal of pharmacology, 2013, Volume: 169, Issue:7

    Topics: Animals; Cardiovascular Diseases; Cell Line; Cells, Cultured; Cisplatin; Doxorubicin; Erythropoietin; Glucosides; HEK293 Cells; Hemoglobins; Hepatocytes; Humans; Kidney; Male; Mice; Mice, Inbred C57BL; Mitochondria; Myocytes, Cardiac; Receptors, Erythropoietin; Stilbenes

2013
2,3,4',5-tetrahydroxystilbene-2-O-β-D-glucoside suppresses expression of adhesion molecules in aortic wall of dietary atherosclerotic rats and promonocytic U937 cells.
    Cell biochemistry and biophysics, 2013, Volume: 67, Issue:3

    Topics: Animals; Aorta; Atherosclerosis; Cell Adhesion Molecules; Diet, High-Fat; Gene Expression Regulation; Glucosides; Humans; Intercellular Adhesion Molecule-1; Lipoproteins, LDL; Male; Monocyte-Macrophage Precursor Cells; Rats; Rats, Sprague-Dawley; RNA, Messenger; Simvastatin; Stilbenes; U937 Cells; Vascular Cell Adhesion Molecule-1

2013
Influence of processing on pharmacokinetic of typical constituents in radix polygoni multiflori after oral administration by LC-ESI-MS/MS.
    Journal of ethnopharmacology, 2013, Jun-21, Volume: 148, Issue:1

    Topics: Animals; Chromatography, Liquid; Drugs, Chinese Herbal; Emodin; Gallic Acid; Glucosides; Male; Medicine, Chinese Traditional; Models, Biological; Plant Roots; Polygonum; Rats; Rats, Sprague-Dawley; Resveratrol; Spectrometry, Mass, Electrospray Ionization; Stilbenes; Tandem Mass Spectrometry

2013
Simultaneous determination of 5 major bioactive components in hugu capsule by HPLC-DAD.
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2012, Volume: 35, Issue:12

    Topics: Capsules; Chlorogenic Acid; Chromatography, High Pressure Liquid; Coumaric Acids; Drug Combinations; Drugs, Chinese Herbal; Flavanones; Flavonoids; Glucosides; Quality Control; Reproducibility of Results; Stilbenes

2012
Neuroprotection by tetrahydroxystilbene glucoside in the MPTP mouse model of Parkinson's disease.
    Toxicology letters, 2013, Oct-24, Volume: 222, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apoptosis Regulatory Proteins; Ataxia; Behavior, Animal; Cell Survival; Corpus Striatum; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Dopaminergic Neurons; Glucosides; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Male; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Neuroprotective Agents; Parkinson Disease; Proto-Oncogene Proteins c-akt; Signal Transduction; Stilbenes; Substantia Nigra; Tyrosine 3-Monooxygenase

2013
TSG (2,3,4' ,5-tetrahydroxystilbene 2-O-β-D-glucoside) suppresses induction of pro-inflammatory factors by attenuating the binding activity of nuclear factor-κB in microglia.
    Journal of neuroinflammation, 2013, Oct-21, Volume: 10

    Topics: Animals; Blotting, Western; Cell Line; Chromatin Immunoprecipitation; Enzyme-Linked Immunosorbent Assay; Glucosides; Mice; Mice, Inbred C57BL; Microglia; NF-kappa B; Rats; Real-Time Polymerase Chain Reaction; Signal Transduction; Stilbenes

2013
2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside (THSG) attenuates human platelet aggregation, secretion and spreading in vitro.
    Thrombosis research, 2014, Volume: 133, Issue:2

    Topics: Adenosine Triphosphate; Blood Platelets; Fibrinogen; Glucosides; Humans; P-Selectin; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Polygonum; Stilbenes

2014
Tetrahydroxystilbene glucoside attenuates neuroinflammation through the inhibition of microglia activation.
    Oxidative medicine and cellular longevity, 2013, Volume: 2013

    Topics: Animals; Cell Line; Enzyme Activation; Glucosides; Humans; Inflammation; Lipopolysaccharides; Mice; Microglia; NADPH Oxidases; Neurons; Neuroprotective Agents; NF-kappa B; Reactive Oxygen Species; Signal Transduction; Stilbenes

2013
The effect of 2,3,4',5-tetrahydroxystilbene-2-O-β-D-glucoside on pressure overload-induced cardiac remodeling in rats and its possible mechanism.
    Planta medica, 2014, Volume: 80, Issue:2-3

    Topics: Animals; Blood Pressure; Glucosides; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Phytotherapy; Plant Extracts; Polygonum; Rats; Stilbenes; Transforming Growth Factor beta1; Ventricular Remodeling

2014
In vitro effects of active components of Polygonum Multiflorum Radix on enzymes involved in the lipid metabolism.
    Journal of ethnopharmacology, 2014, May-14, Volume: 153, Issue:3

    Topics: Cell Line; Cholesterol; Cholesterol 7-alpha-Hydroxylase; Diacylglycerol O-Acyltransferase; Emodin; Fatty Liver; Glucosides; Humans; Hydroxymethylglutaryl CoA Reductases; Plant Roots; Polygonum; Stilbenes; Triglycerides

2014
Potential protection of 2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside against staurosporine-induced toxicity on cultured rat hippocampus neurons.
    Neuroscience letters, 2014, Jul-25, Volume: 576

    Topics: Animals; Apoptosis; Caspase 3; Glucosides; Hippocampus; Neurons; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Primary Cell Culture; Protein Precursors; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Rats, Sprague-Dawley; Signal Transduction; Staurosporine; Stilbenes

2014
Transcriptome profiling and digital gene expression analysis of Fallopia multiflora to discover putative genes involved in the biosynthesis of 2,3,5,4'-tetrahydroxy stilbene-2-O-β-D-glucoside.
    Gene, 2014, Aug-15, Volume: 547, Issue:1

    Topics: Cluster Analysis; Gene Expression Profiling; Genes, Plant; Glucosides; Polygonaceae; Sequence Analysis, RNA; Stilbenes; Transcriptome

2014
Inhibitory effects of 2,3,4',5-tetrahydroxystilbene-2-O-β-D-glucoside on angiotensin II-induced proliferation of vascular smooth muscle cells.
    Chinese journal of integrative medicine, 2015, Volume: 21, Issue:3

    Topics: Angiotensin II; Animals; Cell Cycle; Cell Proliferation; Extracellular Signal-Regulated MAP Kinases; Glucosides; Intracellular Space; Male; Mitogen-Activated Protein Kinase Kinases; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphorylation; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins; Rats, Sprague-Dawley; Reactive Oxygen Species; RNA, Messenger; Stilbenes; Superoxide Dismutase

2015
Tetrahydroxystilbene glucoside protects against oxidized LDL-induced endothelial dysfunction via regulating vimentin cytoskeleton and its colocalization with ICAM-1 and VCAM-1.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2014, Volume: 34, Issue:5

    Topics: Apoptosis; Atherosclerosis; Caspase 3; Cells, Cultured; Cytoskeleton; Down-Regulation; Endothelial Cells; Glucosides; Human Umbilical Vein Endothelial Cells; Humans; Intercellular Adhesion Molecule-1; Lipoproteins, LDL; NF-kappa B; Protective Agents; Signal Transduction; Smad Proteins, Receptor-Regulated; Stilbenes; Vascular Cell Adhesion Molecule-1; Vimentin

2014
Effects of tetrahydroxystilbene glucoside on mouse liver cytochrome P450 enzyme expressions.
    Xenobiotica; the fate of foreign compounds in biological systems, 2015, Volume: 45, Issue:4

    Topics: Animals; Body Weight; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Glucosides; Liver; Male; Membrane Proteins; Mice; Organ Size; PPAR alpha; Pregnane X Receptor; Receptors, Aryl Hydrocarbon; Receptors, Steroid; Stilbenes

2015
2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside protects human umbilical vein endothelial cells against lysophosphatidylcholine-induced apoptosis by upregulating superoxide dismutase and glutathione peroxidase.
    IUBMB life, 2014, Volume: 66, Issue:10

    Topics: Apoptosis; Biomarkers; Blotting, Western; Cell Proliferation; Cells, Cultured; Glucosides; Glutathione Peroxidase; Human Umbilical Vein Endothelial Cells; Humans; Lysophosphatidylcholines; Membrane Potential, Mitochondrial; Oxidative Stress; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes; Superoxide Dismutase

2014
Attempt to synthesize 2,3,5,4'-tetrahydroxystilbene derived from 2,3,5,4'-tetrahydroxystilbene-2-O-β-glucoside (THSG).
    Chemical & pharmaceutical bulletin, 2015, Volume: 63, Issue:2

    Topics: Catalysis; Glucosides; Palladium; Stilbenes

2015
Efficacy of antioxidants as a Complementary and Alternative Medicine (CAM) in combination with the chemotherapeutic agent doxorubicin.
    Integrative cancer therapies, 2015, Volume: 14, Issue:2

    Topics: 3T3 Cells; Animals; Antibiotics, Antineoplastic; Antioxidants; Antrodia; Breast Neoplasms; Complementary Therapies; Curcumin; Doxorubicin; Drug Synergism; Female; Glucosides; Humans; MCF-7 Cells; Mice; Plant Extracts; Reactive Oxygen Species; Resveratrol; Stilbenes; Superoxide Dismutase

2015
Tetrahydroxystilbene glucoside improves TNF-α-induced endothelial dysfunction: involvement of TGFβ/Smad pathway and inhibition of vimentin expression.
    The American journal of Chinese medicine, 2015, Volume: 43, Issue:1

    Topics: Active Transport, Cell Nucleus; Apoptosis; Atherosclerosis; Cells, Cultured; Cytoprotection; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Gene Expression Regulation, Developmental; Glucosides; Humans; L-Lactate Dehydrogenase; Polygonum; Signal Transduction; Smad Proteins; Stilbenes; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Umbilical Veins; Vimentin

2015
Tetrahydroxystilbene glucoside extends mouse life span via upregulating neural klotho and downregulating neural insulin or insulin-like growth factor 1.
    Neurobiology of aging, 2015, Volume: 36, Issue:3

    Topics: Aging; Animals; Cells, Cultured; Down-Regulation; Gene Expression Regulation, Developmental; Glucosides; Glucuronidase; Insulin; Insulin-Like Growth Factor I; Klotho Proteins; Longevity; Memory; Mice, Inbred Strains; Models, Animal; Polygonatum; Signal Transduction; Stilbenes; Up-Regulation

2015
[Comparative study on pharmacokinetics and tissue distribution of cis- and trans-2,3,5,4'-Tetrahydroxystilbene-2-O-beta-D-glucosides in mice].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2014, Volume: 37, Issue:9

    Topics: Acetic Acid; Animals; Glucosides; Half-Life; Mice; Stilbenes

2014
Proliferation of rat cardiac stem cells is induced by 2, 3, 5, 4'-tetrahydroxystilbene-2-O-β-D-glucoside in vitro.
    Life sciences, 2015, Jul-01, Volume: 132

    Topics: Analysis of Variance; Animals; Blotting, Western; Cell Proliferation; Cells, Cultured; DNA Primers; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Gene Expression Profiling; Glucosides; In Vitro Techniques; Myoblasts, Cardiac; Myocardium; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Stem Cell Factor; Stilbenes; Vascular Endothelial Growth Factor A

2015
TSG (2,3,5,4'-Tetrahydroxystilbene-2-O- β -D-glucoside) from the Chinese Herb Polygonum multiflorum Increases Life Span and Stress Resistance of Caenorhabditis elegans.
    Oxidative medicine and cellular longevity, 2015, Volume: 2015

    Topics: Animals; Antioxidants; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Drugs, Chinese Herbal; Fallopia multiflora; Free Radical Scavengers; Glucosides; Glutathione Transferase; Heat-Shock Response; Longevity; Mutation; Reactive Oxygen Species; Stilbenes; Stress, Physiological; Superoxide Dismutase

2015
Activating mitochondrial function and haemoglobin expression with EH-201, an inducer of erythropoietin in neuronal cells, reverses memory impairment.
    British journal of pharmacology, 2015, Volume: 172, Issue:19

    Topics: Animals; Astrocytes; Cells, Cultured; Disease Models, Animal; Erythropoietin; Female; Glucosides; Hemoglobins; Hydrogen Peroxide; Kainic Acid; Male; Memory Disorders; Mice, Inbred C57BL; Mitochondria; Neuroprotective Agents; PC12 Cells; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Rats; Reactive Oxygen Species; Stilbenes; Succinate Dehydrogenase; Transcription Factors

2015
Tetrahydroxystilbene Glucoside Improves Neurotrophic Factors Release in Cultured Astroglia.
    CNS & neurological disorders drug targets, 2016, Volume: 15, Issue:4

    Topics: Animals; Animals, Newborn; Astrocytes; Brain; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Fallopia multiflora; Female; Glucosides; Mitogen-Activated Protein Kinase 3; Nerve Growth Factors; Neuroprotective Agents; Rats; Rats, Wistar; Signal Transduction; Stilbenes

2016
Tetrahydroxystilbene glucoside ameliorates memory and movement functions, protects synapses and inhibits α-synuclein aggregation in hippocampus and striatum in aged mice.
    Restorative neurology and neuroscience, 2015, Volume: 33, Issue:4

    Topics: Aging; alpha-Synuclein; Animals; Avoidance Learning; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cerebral Cortex; Corpus Striatum; Female; Glucosides; Hippocampus; Memory; Memory Disorders; Mice, Inbred C57BL; Motor Activity; Movement Disorders; Neuroprotective Agents; Nootropic Agents; Protein Aggregates; Stilbenes; Synapses; Treatment Outcome

2015
Naturally Occurring Stilbenoid TSG Reverses Non-Alcoholic Fatty Liver Diseases via Gut-Liver Axis.
    PloS one, 2015, Volume: 10, Issue:10

    Topics: Animals; Diet, High-Fat; Flow Cytometry; Glucosides; Inflammation; Intestinal Mucosa; Liver; Male; Microbiota; Non-alcoholic Fatty Liver Disease; Rats; Rats, Sprague-Dawley; Signal Transduction; Stilbenes

2015
Protective effects of 2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside in the MPTP-induced mouse model of Parkinson's disease: Involvement of reactive oxygen species-mediated JNK, P38 and mitochondrial pathways.
    European journal of pharmacology, 2015, Nov-15, Volume: 767

    Topics: Animals; Apoptosis Regulatory Proteins; Behavior, Animal; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Glucosides; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Signaling System; Mice; Mitochondria; Neuroprotective Agents; Parkinsonian Disorders; Phosphorylation; Reactive Oxygen Species; Stilbenes; Tyrosine 3-Monooxygenase

2015
TSG attenuates LPC-induced endothelial cells inflammatory damage through notch signaling inhibition.
    IUBMB life, 2016, Volume: 68, Issue:1

    Topics: Apoptosis; Basic Helix-Loop-Helix Transcription Factors; C-Reactive Protein; Cell Adhesion; Cell Movement; Cell Survival; Chemokine CCL2; Dipeptides; Gene Knockdown Techniques; Glucosides; Homeodomain Proteins; Human Umbilical Vein Endothelial Cells; Humans; Interleukin-6; Lysophosphatidylcholines; Receptor, Notch1; Signal Transduction; Stilbenes; Transcription Factor HES-1

2016
Chronic administration tetrahydroxystilbene glucoside promotes hippocampal memory and synaptic plasticity and activates ERKs, CaMKII and SIRT1/miR-134 in vivo.
    Journal of ethnopharmacology, 2016, Aug-22, Volume: 190

    Topics: Animals; Behavior, Animal; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Dendritic Spines; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Fear; Glucosides; Hippocampus; Memory; Mice, Inbred C57BL; MicroRNAs; Neuronal Plasticity; Nootropic Agents; Phosphorylation; Recognition, Psychology; Signal Transduction; Sirtuin 1; Stilbenes; Time Factors

2016
2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside suppresses human colorectal cancer cell metastasis through inhibiting NF-κB activation.
    International journal of oncology, 2016, Volume: 49, Issue:2

    Topics: Cell Movement; Colorectal Neoplasms; Glucosides; HT29 Cells; Humans; Neoplasm Metastasis; NF-kappa B; Signal Transduction; Stilbenes

2016
Cardiac stem cell transplantation with 2,3,5,4'-tetrahydroxystilbehe-2-O-β-d-glucoside improves cardiac function in rat myocardial infarction model.
    Life sciences, 2016, Aug-01, Volume: 158

    Topics: Animals; Disease Models, Animal; Glucosides; Heart Rate; Male; Myocardial Infarction; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; Stem Cell Transplantation; Stilbenes

2016
Arginase Inhibitor 2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-Glucoside Activates Endothelial Nitric Oxide Synthase and Improves Vascular Function.
    Planta medica, 2017, Volume: 83, Issue:3-04

    Topics: Acetylcholine; Animals; Aorta; Apolipoproteins E; Arginase; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Glucosides; Human Umbilical Vein Endothelial Cells; Humans; Male; Mice; Mice, Inbred C57BL; Nitric Oxide; Nitric Oxide Synthase Type III; Nitroprusside; Phenylephrine; Reactive Oxygen Species; Stilbenes; Superoxides; Vasoconstriction

2017
The inhibition of macrophage foam cell formation by tetrahydroxystilbene glucoside is driven by suppressing vimentin cytoskeleton.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2016, Volume: 83

    Topics: Apoptosis; Blotting, Western; Caspase 3; Cell Differentiation; Cell Nucleus; Cytoskeleton; DNA Fragmentation; Enzyme Activation; Foam Cells; Glucosides; Humans; Intercellular Adhesion Molecule-1; Lipoproteins, LDL; Signal Transduction; Smad Proteins; Stilbenes; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta1; U937 Cells; Vimentin

2016
PPAR-γ is involved in the protective effect of 2,3,4',5-tetrahydroxystilbene-2-O-beta-D-glucoside against cardiac fibrosis in pressure-overloaded rats.
    European journal of pharmacology, 2016, Nov-15, Volume: 791

    Topics: Angiotensin II; Animals; Blood Pressure; Cardiotonic Agents; Cell Differentiation; Cell Proliferation; Collagen Type I; Collagen Type III; Fibroblasts; Fibronectins; Fibrosis; Gene Expression Regulation; Glucosides; Heart; Male; Myocardium; Plasminogen Activator Inhibitor 1; PPAR gamma; Pressure; Rats; Stilbenes

2016
2,3,4',5-tetrahydroxystilbene-2-O-β-d-glucoside exerts anti-inflammatory effects on lipopolysaccharide-stimulated microglia by inhibiting NF-κB and activating AMPK/Nrf2 pathways.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2016, Volume: 97

    Topics: AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents; Apoptosis; Blotting, Western; Cell Proliferation; Cells, Cultured; Cytokines; Glucosides; Inflammation; Lipopolysaccharides; Mice; Mice, Inbred ICR; Microglia; NF-E2-Related Factor 2; NF-kappa B; Nitric Oxide; Phosphorylation; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Stilbenes

2016
2,3,5,4'-Tetrahydroxystilbene-2-O-β-d-glucoside exerted protective effects on diabetic nephropathy in mice with hyperglycemia induced by streptozotocin.
    Food & function, 2016, Nov-09, Volume: 7, Issue:11

    Topics: Albuminuria; Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Gene Expression Regulation; Glucosides; Kidney; Male; Mice; Mice, Inbred C57BL; RNA, Messenger; Stilbenes

2016
2,3,5,4'-Tetrahydroxystilbene-2-O-
    Oxidative medicine and cellular longevity, 2016, Volume: 2016

    Topics: Animals; Glucosides; Glucuronidase; Klotho Proteins; Longevity; Male; Rats; Rats, Wistar; Stilbenes

2016
2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-Glucoside Attenuates Ischemia/Reperfusion-Induced Brain Injury in Rats by Promoting Angiogenesis.
    Planta medica, 2017, Volume: 83, Issue:8

    Topics: Angiogenesis Inducing Agents; Angiotensin I; Animals; Blotting, Western; Brain Injuries; Brain Ischemia; Fallopia multiflora; Glucosides; Infarction, Middle Cerebral Artery; Male; Neovascularization, Physiologic; Neuroprotective Agents; Platelet Endothelial Cell Adhesion Molecule-1; Rats; Rats, Sprague-Dawley; Receptor, TIE-2; Reperfusion Injury; Stilbenes; Stroke; Vascular Endothelial Growth Factor A

2017
Mechanism of 2,3,4',5-Tetrahydroxystilbene 2-O-β-D-Glucoside-Induced Upregulation of Glutamate Transporter 1 Protein Expression in Mouse Primary Astrocytes.
    Pharmacology, 2017, Volume: 99, Issue:3-4

    Topics: Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Excitatory Amino Acid Transporter 2; Gene Expression Regulation; Glucosides; Mice; Mice, Inbred C57BL; Stilbenes; Up-Regulation

2017
2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-glucoside protects murine hearts against ischemia/reperfusion injury by activating Notch1/Hes1 signaling and attenuating endoplasmic reticulum stress.
    Acta pharmacologica Sinica, 2017, Volume: 38, Issue:3

    Topics: Animals; Apoptosis; Cardiotonic Agents; Cell Line; Endoplasmic Reticulum Stress; Glucosides; Male; Mice, Inbred C57BL; Myoblasts, Cardiac; Myocardial Reperfusion Injury; Rats; Receptor, Notch1; Signal Transduction; Stilbenes; Transcription Factor HES-1

2017
Enhanced absorption and inhibited metabolism of emodin by 2, 3, 5, 4'-tetrahydroxystilbene-2-O-β-D-glucopyranoside: Possible mechanisms for Polygoni Multiflori Radix-induced liver injury.
    Chinese journal of natural medicines, 2017, Volume: 15, Issue:6

    Topics: Caco-2 Cells; Chemical and Drug Induced Liver Injury; Emodin; Fallopia multiflora; Glucosides; Glucuronosyltransferase; Humans; Plant Roots; Stilbenes

2017
2,3,4',5-tetrahydroxystilbene-2-O-β-d-glycoside attenuates atherosclerosis in apolipoprotein E-deficient mice: role of reverse cholesterol transport.
    Canadian journal of physiology and pharmacology, 2018, Volume: 96, Issue:1

    Topics: Animals; Apolipoproteins E; Atherosclerosis; Biological Transport; Cholesterol; Fatty Liver; Foam Cells; Glucosides; Hyperlipidemias; Inflammation; Lipid Metabolism; Macrophages; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; RAW 264.7 Cells; Stilbenes

2018
2,3,5,4‑tetrahydroxy diphenylethylene‑2‑O‑glucoside inhibits the adhesion and invasion of A549 human lung cancer cells.
    Molecular medicine reports, 2017, Volume: 16, Issue:6

    Topics: Antineoplastic Agents; Biomarkers; Cell Adhesion; Cell Line, Tumor; Cell Movement; Gene Expression Regulation; Glucosides; Humans; Lung Neoplasms; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Stilbenes

2017
The natural compound 2,3,5,4'-tetrahydroxystilbene-2-O-β-d glucoside protects against adriamycin-induced nephropathy through activating the Nrf2-Keap1 antioxidant pathway.
    Environmental toxicology, 2018, Volume: 33, Issue:1

    Topics: Albuminuria; Animals; Antioxidants; Cell Line; Doxorubicin; Female; Glucosides; Heme Oxygenase-1; Hypercholesterolemia; Kelch-Like ECH-Associated Protein 1; Kidney; Lipid Peroxidation; Mice; Mice, Inbred BALB C; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Polygonum; RNA Interference; RNA, Small Interfering; Stilbenes

2018
Tetrahydroxystilbene glucoside modulates amyloid precursor protein processing via activation of AKT-GSK3β pathway in cells and in APP/PS1 transgenic mice.
    Biochemical and biophysical research communications, 2018, 01-01, Volume: 495, Issue:1

    Topics: Amyloid beta-Protein Precursor; Animals; Brain; Dose-Response Relationship, Drug; Enzyme Activation; Glucosides; Glycogen Synthase Kinase 3 beta; HEK293 Cells; Humans; Metabolic Networks and Pathways; Mice; Mice, Transgenic; Oncogene Protein v-akt; Stilbenes

2018
2,3,5,4'‑Tetrahydroxystilbene‑2‑O‑β‑D‑glucoside inhibits septic serum‑induced inflammatory injury via interfering with the ROS‑MAPK‑NF‑κB signaling pathway in pulmonary aortic endothelial cells.
    International journal of molecular medicine, 2018, Volume: 41, Issue:3

    Topics: Animals; Aorta; Cell Survival; Cells, Cultured; Cytokines; Endothelial Cells; Glucosides; Inflammation; Lung; Male; Mitogen-Activated Protein Kinases; NF-kappa B; Phosphorylation; Rats, Sprague-Dawley; Reactive Oxygen Species; RNA, Messenger; Sepsis; Signal Transduction; Stilbenes; Superoxides

2018
In Vitro and In Vivo Anti-Osteoarthritis Effects of 2,3,5,4'-Tetrahydroxystilbene-2-O-β-d-Glucoside from Polygonum Multiflorum.
    Molecules (Basel, Switzerland), 2018, Mar-03, Volume: 23, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Chondrocytes; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Edema; Gene Expression Regulation; Glucosides; Hindlimb; Iodoacetic Acid; Lipopolysaccharides; Male; Matrix Metalloproteinase 13; Mice; Nitric Oxide; Nitric Oxide Synthase Type II; Osteoarthritis; Polygonum; Primary Cell Culture; Rats; RAW 264.7 Cells; Stilbenes

2018
A surface magnetic imprinted polymers as artificial receptors for selective and efficient capturing of new neuronal nitric oxide synthase-post synaptic density protein-95 uncouplers.
    Journal of pharmaceutical and biomedical analysis, 2018, May-30, Volume: 154

    Topics: Animals; Cell Line, Tumor; Disks Large Homolog 4 Protein; Emodin; Glucosides; Magnetics; Molecular Imprinting; Neuroprotective Agents; Nitric Oxide Synthase Type I; PC12 Cells; Polymers; Post-Synaptic Density; Rats; Receptors, Artificial; Solid Phase Extraction; Solvents; Stilbenes

2018
Tetrahydroxystilbene Glucoside Delayed Senile Symptoms in Old Mice via Regulation of the AMPK/SIRT1/PGC-1α Signaling Cascade.
    Gerontology, 2018, Volume: 64, Issue:5

    Topics: Aging; AMP-Activated Protein Kinases; Animals; Bone Density; Cell Line; Drugs, Chinese Herbal; Energy Intake; Female; Glucosides; HeLa Cells; Humans; Mice; Mice, Inbred C57BL; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Signal Transduction; Sirtuin 1; Stilbenes

2018
Quantification of eight active ingredients in crude and processed radix polygoni multiflori applying miniaturized matrix solid-phase dispersion microextraction followed by UHPLC.
    Journal of separation science, 2018, Volume: 41, Issue:17

    Topics: Catechin; Chromatography, High Pressure Liquid; Emodin; Fallopia multiflora; Gallic Acid; Glucosides; Particle Size; Solid Phase Microextraction; Stilbenes; Surface Properties

2018
The influence of polysaccharides from Ophiopogon japonicus on 2,3,5,4'-tetrahydroxy-stilbene-2-O-β-d-glucoside about biopharmaceutical properties in vitro and pharmacokinetics in vivo.
    International journal of biological macromolecules, 2018, Volume: 119

    Topics: Drug Interactions; Glucosides; Ophiopogon; Permeability; Polysaccharides; Solubility; Stilbenes

2018
Protective Effects of 2,3,5,4'-Tetrahydroxystilbene-2-
    International journal of molecular sciences, 2018, Aug-28, Volume: 19, Issue:9

    Topics: Animals; Biomarkers; Body Weight; Bone and Bones; Disease Models, Animal; Glucosides; Humans; Mice; Organ Size; Osteoporosis; Ovariectomy; Plant Extracts; Protective Agents; Stilbenes; X-Ray Microtomography

2018
The Protective Effects of 2,3,5,4'-Tetrahydroxystilbene-2-
    International journal of molecular sciences, 2018, Dec-12, Volume: 19, Issue:12

    Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Cell Count; Cytokines; Disease Models, Animal; Female; Glucosides; Immunoglobulin Class Switching; Inflammation; Inflammation Mediators; Lung; Mice, Inbred C57BL; Ovalbumin; Protective Agents; Respiratory Hypersensitivity; Stilbenes; Th1 Cells; Th2 Cells

2018
The synergistic effect of 2,3,5,4'-Tetrahydroxystilbene-2-O-β-d-glucoside combined with Adriamycin on MCF-7 breast cancer cells.
    Drug design, development and therapy, 2018, Volume: 12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulatory Proteins; Breast Neoplasms; Cell Survival; Dose-Response Relationship, Drug; Doxorubicin; Drug Synergism; Female; Glucosides; Humans; MCF-7 Cells; Phosphatidylinositol 3-Kinase; Proto-Oncogene Proteins c-akt; Signal Transduction; Stilbenes; Vascular Endothelial Growth Factor A

2018
Involvement of stromal cell-derived factor-1α (SDF-1α), stem cell factor (SCF), fractalkine (FKN) and VEGF in TSG protection against intimal hyperplasia in rat balloon injury.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, Volume: 110

    Topics: Angioplasty, Balloon; Animals; Carotid Artery Injuries; Carotid Artery, Common; Chemokine CX3CL1; Chemokine CXCL12; Glucosides; Hyperplasia; Male; Neointima; Random Allocation; Rats; Rats, Sprague-Dawley; Stem Cell Factor; Stilbenes; Vascular Endothelial Growth Factor A

2019
Dental Pulp Stem Cell Transplantation with 2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-glucoside Accelerates Alveolar Bone Regeneration in Rats.
    Journal of endodontics, 2019, Volume: 45, Issue:4

    Topics: Adolescent; Adult; Alveolar Bone Loss; Alveolar Process; Animals; Bone Regeneration; Cell Differentiation; Dental Pulp; Disease Models, Animal; Female; Glucosides; Humans; Male; Osteogenesis; Rats, Sprague-Dawley; Regenerative Medicine; Stem Cell Transplantation; Stem Cells; Stilbenes; Stimulation, Chemical; Young Adult

2019
2, 3, 4', 5-tetrahydroxystilbene-2-0-β-d Glycoside Attenuates Age- and Diet-Associated Non-Alcoholic Steatohepatitis and Atherosclerosis in LDL Receptor Knockout Mice and Its Possible Mechanisms.
    International journal of molecular sciences, 2019, Apr-01, Volume: 20, Issue:7

    Topics: Aging; Animals; Aorta; Atherosclerosis; Diet, High-Fat; Glucosides; Lipid Metabolism; Liver; Male; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Receptors, LDL; Stilbenes

2019
2,3,5,4'-Tetrahydroxystilbene-2-O-β-d-glucoside attenuates MPP+/MPTP-induced neurotoxicity in vitro and in vivo by restoring the BDNF-TrkB and FGF2-Akt signaling axis and inhibition of apoptosis.
    Food & function, 2019, Sep-01, Volume: 10, Issue:9

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Apoptosis; Brain-Derived Neurotrophic Factor; Cell Survival; Dopaminergic Neurons; Drugs, Chinese Herbal; Fallopia multiflora; Fibroblast Growth Factor 2; Glucosides; Humans; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Parkinson Disease; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; Stilbenes

2019
Inflammation inhibition and gut microbiota regulation by TSG to combat atherosclerosis in ApoE
    Journal of ethnopharmacology, 2020, Jan-30, Volume: 247

    Topics: Administration, Oral; Animals; Aorta; Atherosclerosis; Chemokine CCL2; Diet, High-Fat; Disease Models, Animal; Drugs, Chinese Herbal; Gastrointestinal Microbiome; Glucosides; Humans; Inflammation; Intercellular Adhesion Molecule-1; Lipoproteins, LDL; Male; Mice; Mice, Knockout, ApoE; Polygonum; Stilbenes; Triglycerides; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1

2020
Resveratrol derivative excited postsynaptic potentiation specifically via PKCβ-NMDA receptor mediation.
    Pharmacological research, 2020, Volume: 152

    Topics: Animals; Excitatory Postsynaptic Potentials; Glucosides; Hippocampus; Long-Term Potentiation; Mice, Inbred C57BL; Mice, Transgenic; Protein Kinase C beta; Receptors, N-Methyl-D-Aspartate; Stilbenes

2020
2,3,5,4'-Tetrahydroxystilbene-2-O-β-d-glucoside alleviated the acute hepatotoxicity and DNA damage in diethylnitrosamine-contaminated mice.
    Life sciences, 2020, Feb-15, Volume: 243

    Topics: Alkylating Agents; Animals; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2E1; Cytokines; Diethylnitrosamine; DNA Damage; Dose-Response Relationship, Drug; Glucosides; Inflammation Mediators; Liver; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Stilbenes

2020
In vitro and in situ study on characterization and mechanism of the intestinal absorption of 2,3,5,4'-tetrahydroxy-stilbene-2-O-β-D-glucoside.
    BMC pharmacology & toxicology, 2020, 01-22, Volume: 21, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Cell Survival; Female; Gastric Juice; Glucosides; Humans; Intestinal Absorption; Intestinal Mucosa; Intestinal Secretions; Male; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Rats, Sprague-Dawley; Stilbenes

2020
2,3,5,4'-Tetrahydroxystilbene-2-O-β-d-glucoside Restores BDNF-TrkB and FGF2-Akt Signaling Axis to Attenuate Stress-induced Depression.
    Neuroscience, 2020, 03-15, Volume: 430

    Topics: Animals; Brain-Derived Neurotrophic Factor; Depression; Fibroblast Growth Factor 2; Glucosides; Hippocampus; Mice; Proto-Oncogene Proteins c-akt; Signal Transduction; Stilbenes; Stress, Psychological

2020
2,3,5,4'-tetrahydroxystilbence-2-O-β-D-glucoside attenuates hepatic steatosis via IKKβ/NF-κB and Keap1-Nrf2 pathways in larval zebrafish.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020, Volume: 127

    Topics: Animals; Cholesterol, Dietary; Disease Models, Animal; Glucosides; I-kappa B Kinase; Kelch-Like ECH-Associated Protein 1; Lipid Metabolism; NF-E2-Related Factor 2; NF-kappa B; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Signal Transduction; Stilbenes; Zebrafish; Zebrafish Proteins

2020
2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside induces autophagy of liver by activating PI3K/Akt and Erk pathway in prediabetic rats.
    BMC complementary medicine and therapies, 2020, Jun-08, Volume: 20, Issue:1

    Topics: Animals; Autophagy; Fallopia multiflora; Glucosides; Liver; Male; MAP Kinase Signaling System; Molecular Structure; Phosphatidylinositol 3-Kinases; Prediabetic State; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Stilbenes

2020
Otoprotective Effect of 2,3,4',5-Tetrahydroxystilbene-2-
    Molecules (Basel, Switzerland), 2020, Jul-06, Volume: 25, Issue:13

    Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Cell Line; Cell Survival; Fallopia multiflora; Gentamicins; Glucosides; L-Lactate Dehydrogenase; Membrane Potential, Mitochondrial; Mice; Mitochondria; Ototoxicity; Reactive Oxygen Species; Stilbenes; Superoxide Dismutase

2020
Pharmacological and metagenomics evidence of polysaccharide from Polygonum multiflorum in the alleviation of insulin resistance.
    International journal of biological macromolecules, 2020, Dec-01, Volume: 164

    Topics: AMP-Activated Protein Kinases; Animals; Fallopia multiflora; Fatty Acids, Volatile; Feces; Gastrointestinal Microbiome; Glucosides; Insulin; Insulin Resistance; Liver; Male; Metagenomics; Polysaccharides; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; RNA, Ribosomal, 16S; Signal Transduction; Stilbenes

2020
2,3,5,4'-Tetrahydroxystilbene-2-O-β-d-glucoside promotes the effects of dental pulp stem cells on rebuilding periodontal tissues in experimental periodontal defects.
    Journal of periodontology, 2021, Volume: 92, Issue:2

    Topics: Animals; Dental Pulp; Glucosides; Male; Rats; Rats, Sprague-Dawley; Stem Cells; Stilbenes; Vascular Endothelial Growth Factor A; X-Ray Microtomography

2021
2,3,5,4'-Tetrahydroxy-stilbene-2-
    Pharmaceutical biology, 2020, Volume: 58, Issue:1

    Topics: Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Cell Line; Cell Survival; Chemical and Drug Induced Liver Injury; Core Binding Factor Alpha 2 Subunit; Glucosides; Hepatocytes; Humans; MicroRNAs; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Stilbenes; TOR Serine-Threonine Kinases

2020
2,3,5,4'-tetrahydoxystilbene-2-O-β-D-glucoside eliminates staurosporine-induced cytotoxicity by restoring BDNF-TrkB/Akt signaling axis.
    International journal of medical sciences, 2020, Volume: 17, Issue:14

    Topics: Animals; Animals, Newborn; Apoptosis; Brain-Derived Neurotrophic Factor; Carbazoles; Cell Survival; Cells, Cultured; Chromones; Fallopia multiflora; Glucosides; Hippocampus; Indole Alkaloids; Morpholines; Neurons; Neuroprotective Agents; Primary Cell Culture; Proto-Oncogene Proteins c-akt; Rats; Receptor, trkB; Signal Transduction; Staurosporine; Stilbenes

2020
2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-glucoside, a major bioactive component from Polygoni multiflori Radix (Heshouwu) suppresses DSS induced acute colitis in BALb/c mice by modulating gut microbiota.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 137

    Topics: Animals; Anti-Inflammatory Agents; Colitis, Ulcerative; Colon; Cytokines; Dextran Sulfate; DNA, Bacterial; Feces; Gastrointestinal Microbiome; Glucosides; Male; Mice; Mice, Inbred BALB C; Plant Extracts; Plants, Medicinal; RNA, Ribosomal, 16S; Stilbenes; Tight Junction Proteins

2021
Reduction of breast tumor drug resistance by 2,3,5,4'-tetrahydroxystilbene for exhibition synergic chemotherapeutic effect.
    PloS one, 2021, Volume: 16, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Docetaxel; Doxorubicin; Drug Resistance, Neoplasm; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; Glucosides; Humans; MCF-7 Cells; Stilbenes; Zebrafish

2021
2,3,4',5‑Tetrahydroxystilbene‑2‑O‑β‑D‑glucoside ameliorates gentamicin‑induced ototoxicity by modulating autophagy via Sesn2/AMPK/mTOR signaling.
    International journal of molecular medicine, 2022, Volume: 49, Issue:5

    Topics: AMP-Activated Protein Kinases; Animals; Autophagy; Gentamicins; Glucosides; Mice; Ototoxicity; Stilbenes; TOR Serine-Threonine Kinases

2022
A Systematic Strategy for the Characterization of 2,3,5,4'-Tetrahydroxystilbene-2-
    Journal of agricultural and food chemistry, 2022, Jun-29, Volume: 70, Issue:25

    Topics: Animals; Chromatography, High Pressure Liquid; Chromatography, Liquid; Glucosides; Rats; Stilbenes

2022