Page last updated: 2024-08-22

glucosamine and lipid a

glucosamine has been researched along with lipid a in 92 studies

Research

Studies (92)

TimeframeStudies, this research(%)All Research%
pre-199031 (33.70)18.7374
1990's21 (22.83)18.2507
2000's21 (22.83)29.6817
2010's18 (19.57)24.3611
2020's1 (1.09)2.80

Authors

AuthorsStudies
Caroff, M; Chaby, R; Le Dur, A; Szabó, L1
Egan, A; Lehmann, V; Minner, I; Redmond, J1
Caird, JD; Wiseman, GM1
Raziuddin, S1
Hase, S; Reitschel, ET1
Kanamori, M1
Julák, J; Levin, J; Michalec, C; Sourek, J; Stránský, K; Trnka, T1
Diedrich, DL; McAllister, SA; Stein, MA; Torian, BE1
Moran, AP; Scholz, D; Zähringer, U1
Bhat, UR; Carlson, RW1
Hasegawa, A; Homma, JY; Ikeda, S; Kiso, M; Matsuura, M; Nakatsuka, M; Nishimura, C1
Moran, AP; Rietschel, ET; Scholz, D; Seydel, U; Stütz, P; Zähringer, U1
Moll, H; Rietschel, ET; Zähringer, U1
Auling, G; Krauss, JH; Mayer, H; Puvanesarajah, V; Stacey, G; Urbanik-Sypniewska, T1
Hasegawa, A; Homma, JY; Kiso, M; Kumazawa, Y; Matsuura, M; Nakatsuka, M1
Harada, K; Ikeda, T; Kotani, S; Ogawa, T; Okamura, H; Takada, H; Takahashi, I; Tamura, T; Tanaka, S; Tsujimoto, M1
Munford, RS; Peterson, AA1
Bertók, L; Elekes, E; Galanos, C; Lüderitz, O1
Hasegawa, A; Homma, JY; Kiso, M; Kumazawa, Y; Ogawa, Y; Takimoto, H; Yamamoto, A1
Achiwa, K; Ikeda, K; Masuzawa, T; Shimizu, C; Shimizu, T; Yanagihara, Y1
Achiwa, K; Ikeda, K; Nakamoto, S; Takahashi, T1
Hasegawa, A; Homma, JY; Kiso, M; Kumazawa, Y; Maruyama, T; Matsuura, M1
Fujishima, Y; Fujita, M; Hasegawa, A; Ishida, H; Kiso, M; Ogawa, Y; Tanaka, S1
Achiwa, K; Akiyama, S; Masuzawa, T; Nakamoto, S; Shimizu, T; Yanagihara, Y2
Azuma, I; Fujishima, Y; Hasegawa, A; Ishida, H; Kigawa, K; Kiso, M; Ogawa, Y1
Achiwa, K; Nakamoto, S1
Akiyama, Y; Arata, S; Egawa, K; Kasai, N; Mashimo, J; Tanaka, C; Tanaka, S1
Gorbach, VI; Luk'ianov, PA; Ovodov, IuS; Solov'eva, TF1
Lorkiewicz, Z; Russa, R; Urbanik, T1
Anderson, L; Mascagni, P; Nashed, MA; Qureshi, N; Raetz, CR; Takayama, K1
Rietschel, ET; Sidorczyk, Z; Zähringer, U1
Lingens, F; Weisshaar, R1
Borowiak, D; Holst, O; Mayer, H; Weckesser, J1
Hasegawa, A; Homma, JY; Kiso, M; Kojima, Y; Kubota, Y; Matsuura, M; Yamamoto, A1
Blache, D; Bruneteau, M; Michel, G1
Nelson, DR; Rittenberg, SC1
Humphrey, DR; Rosenberry, TL; Sevlever, D1
Achiwa, K; Arakawa, M; Ikeda, K; Suhara, Y1
Caroff, M; Deprun, C; Karibian, D; Richards, JC1
Bryn, K; Eng, J; Jantzen, E; Sonesson, A; Tangen, T; Zähringer, U1
Tanamoto, K1
Eustache, J; Grob, A; Retscher, H1
Bhat, UR; Carlson, RW; Forsberg, LS1
Achiwa, K; Asahara, T; Ikeda, K1
Arata, S; Friedman, H; Kasai, N; Klein, TW1
Brade, H; Brade, L; Holst, O1
Lindner, B; Moran, AP; Walsh, EJ1
Knirel, YA; Moll, H; Moriyón, I; Sinnwell, V; Velasco, J; Zähringer, U1
Kiang, J; Lee, YC; Szu, SC; Tang, M; Wang, LX1
Aussel, L; Brunelle, A; Caroff, M; Karibian, D1
Aussel, L; Brisson, JR; Caroff, M; Perry, MB1
Que, NL; Raetz, CR; Ribeiro, AA1
Caroff, M; Monteiro, MA; Perry, MB; Thérisod, H1
Kurakata, S; Shiozaki, M; Wakabayashi, T1
Brandenburg, K; Heine, H; Ishida, H; Kiso, M; Koch, MH; Matsuura, M; Müller, M; Seydel, U1
Corsaro, MM; Lanzetta, R; Parrilli, M; Piaz, FD1
Cotter, RJ; Lin, S; Que-Gewirth, NL; Raetz, CR1
Cotter, RJ; Kalb, SR; Karbarz, MJ; Que-Gewirth, NL; Raetz, CR1
BURTON, AJ; CARTER, HE1
Andrä, J; Brandenburg, K; Garidel, P; Hussein, A; Koch, MH; Slaba, K; Toman, R1
Choma, A; Sowinski, P1
Gorshkova, NM; Isakov, VV; Kapustina, NV; Krasikova, IN; Solov'eva, TF1
Bielefeldt-Ohmann, H; Correia, Jda S; Crane, RT; Fling, SP; Fort, MM; Hershberg, RM; Jeffery, E; Johnson, DA; Mozaffarian, A; Persing, DH; Probst, P; Stöver, AG; Ulevitch, RJ1
Casabuono, AC; Couto, AS; D'Antuono, A; Erra-Balsells, R; Lepek, V; Nonami, H; Sato, Y; Ugalde, R1
Fodorová, M; Toman, R; Vadovic, P1
Blanot, D; Caroff, M; Fernandez, R; Marr, N; Tirsoaga, A1
Airhart, CL; Bohach, GA; Deobald, CF; Hovde, CJ; Lee, SS; Minnich, SA; Rohde, HN2
Arnold, JS; Bazin, HG; Bess, LS; Bowen, WS; Cluff, CW; Evans, JT; Fling, SP; Johnson, CL; Johnson, DA; Livesay, MT; Mozaffarian, A; Murray, TJ; Ryter, KT1
Caroff, M; El Hamidi, A; Karibian, D; Novikov, A; Perry, MB1
Cohen, IE; Ernst, RK; Kalhorn, TF; Kiavand, A; Nelson, AK1
Brandenburg, K; Fujimoto, Y; Fukase, K; Garidel, P; Gutsmann, T; Howe, J; Koch, MH; Martínez-de-Tejada, G; Moriyon, I; Schromm, AB; Zähringer, U1
Azadi, P; Brahamsha, B; Palenik, B; Snyder, DS1
De Wit, D; Goldman, M; Hermand, P; Legat, A; Thomas, S; Van Mechelen, M1
Caroff, M; Fernandez, RC; Hajjar, AM; Marr, N; Novikov, A; Shah, NR; Yam, CS1
Moran, AP1
Basheer, SM; Caroff, M; Guiso, N; Novikov, A; Tirsoaga, A1
Bowen, WS; Evans, JT; Hutton, MM; Johnson, DA; Minns, LA; Mitchell, TC1
AlBitar-Nehme, S; Basheer, SM; Caroff, M; Fernandez, RC; Hamidi, AE; Hirst, M; Moksa, M; Novikov, A; Perry, MB; Shah, NR; Tirsoaga, A; Trento, I1
Elahi, S; Ernst, RK; Gerdts, V; Harvill, ET; Hittle, LE; Muse, SJ; Preston, A; Rolin, O; Safi, C1
Balamurugan, K; Radhakrishnan, S; Vigneshkumar, B1
Fernandez, RC; Hancock, RE; Shah, NR1
Artner, D; Beyaert, R; Fernández-Alonso, Mdel C; Garate, JA; Haegman, M; Heine, H; Jiménez-Barbero, J; Kosma, P; Oostenbrink, C; Stöckl, J; Zamyatina, A1
Bazin, HG; Bowen, WS; Evans, JT; Johnson, DA; Khalaf, JK; Livesay, MT; Ryter, KT; Ward, JR1
Beyaert, R; Haegman, M; Hofinger, A; Hollaus, R; Ittig, S; Kosma, P; Zamyatina, A1
Evans-Atkinson, T; Fernandez, RC; Hajjar, AM; Maeshima, N1
Gao, N; Miller, MD; Olivier, NB; Ross, PL1
Choma, A; Komaniecka, I; Mazur, A; Sroka-Bartnicka, A; Zamlynska, K; Zebracki, K1
Akinbobuyi, B; Chang, CA; Kane, RR; Naziruddin, B; Quintana, JM; Yoshimatsu, G1
Casabuono, AC; Couto, AS; Fernández, J; Hozbor, D; Sisti, F1
Chiodo, F; Codée, JDC; de Jong, AR; Filippov, DV; Meeuwenoord, NJ; Ossendorp, F; Overkleeft, HS; Peterse, E; Reintjens, NRM; Tondini, E; van der Marel, GA1

Other Studies

92 other study(ies) available for glucosamine and lipid a

ArticleYear
A novel type of endotoxin structure present in Bordetella pertussis. Isolation of two different polysaccharides bound to lipid A.
    European journal of biochemistry, 1978, Mar-15, Volume: 84, Issue:2

    Topics: Bordetella pertussis; Endotoxins; Fatty Acids; Glucosamine; Glycolipids; Lipid A; Lipopolysaccharides; Methods; Polysaccharides, Bacterial; Sugar Phosphates

1978
The acceptor for polar head groups of the lipid A component of Salmonella lipopolysaccharides.
    European journal of biochemistry, 1978, May-16, Volume: 86, Issue:2

    Topics: Acetylglucosamine; Amino Sugars; Arabinose; Ethanolamines; Glucosamine; Ketoses; Lipid A; Lipopolysaccharides; Models, Biological; Molecular Weight; Mutation; Organophosphorus Compounds; Phosphates; Salmonella typhimurium; Sugar Acids

1978
Composition of the lipopolysaccharide of Neisseria gonorrhoeae.
    Infection and immunity, 1977, Volume: 16, Issue:2

    Topics: Fatty Acids; Glucosamine; Hexoses; Lipid A; Lipopolysaccharides; Neisseria gonorrhoeae; Spectrophotometry, Infrared

1977
Characterization of lipid A and polysaccharide moieties of the lipopolysaccharides from Vibrio cholerae.
    The Biochemical journal, 1977, Oct-01, Volume: 167, Issue:1

    Topics: Chromatography, Gel; Fatty Acids; Glucosamine; Lipid A; Lipopolysaccharides; Polysaccharides, Bacterial; Vibrio cholerae

1977
The chemical structure of the lipid A component of lipopolysaccharides from Chromobacterium violaceum NCTC 9694.
    European journal of biochemistry, 1977, May-02, Volume: 75, Issue:1

    Topics: Acetylglucosamine; Acetylglucosaminidase; Chromatography, Gas; Chromobacterium; Fatty Acids, Unsaturated; Glucosamine; Lipid A; Lipopolysaccharides; Mass Spectrometry

1977
Biological activities of endotoxins from Yersinia enterocolitica.
    Japanese journal of microbiology, 1976, Volume: 20, Issue:4

    Topics: Adjuvants, Immunologic; Animals; Bacterial Proteins; Carbohydrates; Endotoxins; Fever; Glucosamine; Lipid A; Lipopolysaccharides; Mice; Polysaccharides, Bacterial; Pyrogens; Rabbits; Shwartzman Phenomenon; Yersinia

1976
Composition of lipid A in the S and R forms of Shigella dysenteriae serovar 1.
    Zentralblatt fur Bakteriologie : international journal of medical microbiology, 1992, Volume: 277, Issue:4

    Topics: Animals; Carbohydrates; Fatty Acids; Glucosamine; Lethal Dose 50; Limulus Test; Lipid A; Mice; Mice, Inbred ICR; Serotyping; Shigella dysenteriae

1992
Acquisition of apparently intact and unmodified lipopolysaccharides from Escherichia coli by Bdellovibrio bacteriovorus.
    Journal of bacteriology, 1992, Volume: 174, Issue:9

    Topics: Bacterial Outer Membrane Proteins; Bdellovibrio; Enzyme-Linked Immunosorbent Assay; Epitopes; Escherichia coli; Galactose; Genetic Variation; Glucosamine; Host-Parasite Interactions; Lipid A; Lipopolysaccharides; Microscopy, Immunoelectron; O Antigens; Polysaccharides, Bacterial

1992
Application of methylation analysis in the determination of the structure of disaccharides containing 2,3-diamino-2,3-dideoxy-D-glucose (GlcN3N) associated with the backbone of lipid A.
    Carbohydrate research, 1992, Jul-02, Volume: 231

    Topics: Campylobacter jejuni; Carbohydrate Conformation; Carbohydrate Sequence; Disaccharides; Gas Chromatography-Mass Spectrometry; Glucosamine; Indicators and Reagents; Lipid A; Lipopolysaccharides; Methylation; Molecular Sequence Data; Molecular Structure; Structure-Activity Relationship

1992
A new method for the analysis of amide-linked hydroxy fatty acids in lipid-As from gram-negative bacteria.
    Glycobiology, 1992, Volume: 2, Issue:6

    Topics: Amides; Enterobacteriaceae; Fatty Acids; Gas Chromatography-Mass Spectrometry; Glucosamine; Glycosides; Gram-Negative Bacteria; Hexuronic Acids; Hydroxylation; Kinetics; Lipid A; Methane; Molecular Structure; Rhizobium; Spectrometry, Mass, Fast Atom Bombardment; Trimethylsilyl Compounds

1992
Non-specific protective activity of synthetic lipid A-subunit analogs against microbial infections is influenced by their 2-N- and 3-O-linked acyl substituents in the D-glucosamine backbone.
    Journal of clinical & laboratory immunology, 1990, Volume: 32, Issue:4

    Topics: Adjuvants, Immunologic; Animals; Drug Resistance; Glucosamine; Lipid A; Mice; Mice, Inbred ICR; Pseudomonas Infections; Structure-Activity Relationship; Vaccinia

1990
Structural analysis of the lipid A component of Campylobacter jejuni CCUG 10936 (serotype O:2) lipopolysaccharide. Description of a lipid A containing a hybrid backbone of 2-amino-2-deoxy-D-glucose and 2,3-diamino-2,3-dideoxy-D-glucose.
    European journal of biochemistry, 1991, Jun-01, Volume: 198, Issue:2

    Topics: Campylobacter jejuni; Carbohydrate Conformation; Carbohydrate Sequence; Fatty Acids; Glucosamine; Lipid A; Lipopolysaccharides; Magnetic Resonance Spectroscopy; Mass Spectrometry; Methylation; Molecular Sequence Data

1991
G.l.c.-m.s. analysis of methylated 2-acetamido-2-deoxy-D-glucitol phosphates.
    Carbohydrate research, 1990, Feb-25, Volume: 196

    Topics: Acetylglucosamine; Carbohydrate Sequence; Gas Chromatography-Mass Spectrometry; Glucosamine; Hexosephosphates; Lipid A; Methylation; Molecular Sequence Data; Sugar Phosphates

1990
Lipid A with 2,3-diamino-2,3-dideoxy-glucose in lipopolysaccharides from slow-growing members of Rhizobiaceae and from "Pseudomonas carboxydovorans".
    Archives of microbiology, 1989, Volume: 151, Issue:2

    Topics: Electrophoresis, Polyacrylamide Gel; Glucosamine; Lipid A; Lipopolysaccharides; Phylogeny; Pseudomonas; Rhizobiaceae; Rhizobium

1989
Enhancement of nonspecific resistance to bacterial infections and tumor regressions by treatment with synthetic lipid A-subunit analogs. Critical role of N- and 3-O-linked acyl groups in 4-O-phosphono-D-glucosamine derivatives.
    International journal of immunopharmacology, 1989, Volume: 11, Issue:4

    Topics: Adjuvants, Immunologic; Animals; Bacterial Infections; Female; Fibrosarcoma; Glucosamine; Immunity, Innate; Lipid A; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Neoplasm Transplantation; Pseudomonas Infections

1989
Low endotoxic activities of synthetic Salmonella-type lipid A with an additional acyloxyacyl group on the 2-amino group of beta (1-6) glucosamine disaccharide 1,4'-bisphosphate.
    Infection and immunity, 1986, Volume: 52, Issue:3

    Topics: Adjuvants, Immunologic; Animals; Chick Embryo; Complement Activation; Cytotoxins; Dinoprostone; Endotoxins; Glucosamine; Interferon Type I; Interleukin-1; Leukocyte Count; Limulus Test; Lipid A; Lymphocyte Activation; Macrophage Activation; Macrophages; Mice; Mice, Inbred Strains; Prostaglandins E; Pyrogens; Salmonella; Shwartzman Phenomenon; Structure-Activity Relationship; Superoxides

1986
Dephosphorylation of the lipid A moiety of Escherichia coli lipopolysaccharide by mouse macrophages.
    Infection and immunity, 1987, Volume: 55, Issue:4

    Topics: Animals; Escherichia coli; Glucosamine; Hydrogen-Ion Concentration; Kinetics; Lipid A; Lipopolysaccharides; Macrophages; Mice; Phagocytosis; Phosphoric Monoester Hydrolases

1987
Alterations in the chemical composition and antigenicity of Escherichia coli O89 lipopolysaccharide and lipid A after 60Co gamma irradiation.
    Acta microbiologica Hungarica, 1988, Volume: 35, Issue:3

    Topics: Antigens, Bacterial; Escherichia coli; Fatty Acids; Gamma Rays; Glucosamine; Lipid A; Lipopolysaccharides; Phosphates

1988
Effect of chemical modification at C1 of the glucosamine backbone of lipid A-subunit analog GLA-27 on manifestation of immunopharmacological activity.
    FEBS letters, 1988, Oct-24, Volume: 239, Issue:1

    Topics: Animals; Cell Division; Cells, Cultured; DNA Replication; Glucosamine; Lipid A; Mice; Mice, Inbred C3H; Mitogens; Structure-Activity Relationship; Thymidine; Tumor Necrosis Factor-alpha

1988
Biological activities of chemically synthesized N-acetylneuraminic acid-(alpha 2----6)-monosaccharide analogs of lipid A.
    FEBS letters, 1988, Feb-08, Volume: 228, Issue:1

    Topics: Animals; Cells, Cultured; Glucosamine; Lethal Dose 50; Lipid A; Mice; Mice, Inbred BALB C; Mitogens; N-Acetylneuraminic Acid; Salmonella typhimurium; Sialic Acids; Thymus Gland

1988
Lipid A and related compounds. XV. Efficient synthesis of novel analogs of glucosamine-4-phosphate, the nonreducing sugar moiety of lipid A.
    Chemical & pharmaceutical bulletin, 1987, Volume: 35, Issue:11

    Topics: Antineoplastic Agents; Chemical Phenomena; Chemistry; Glucosamine; Glucosephosphates; Lipid A; Mitogens

1987
Structural requirements for inducing in vitro B lymphocyte activation by chemically synthesized derivatives related to the nonreducing D-glucosamine subunit of lipid A.
    European journal of immunology, 1986, Volume: 16, Issue:9

    Topics: Animals; B-Lymphocytes; Binding Sites; Fatty Acids; Female; Glucosamine; Lipid A; Lymphocyte Activation; Mice; Mice, Inbred C3H; Mitogens; Phosphorylation; Structure-Activity Relationship

1986
Synthesis of the optically active 4-O-phosphono-D-glucosamine derivatives related to the nonreducing-sugar subunit of bacterial lipid A.
    Carbohydrate research, 1987, Apr-15, Volume: 162, Issue:1

    Topics: Glucosamine; Indicators and Reagents; Lipid A; Magnetic Resonance Spectroscopy; Optical Rotation; Spectrophotometry, Infrared; Structure-Activity Relationship; Sugar Phosphates

1987
Biological activities of chemically synthesized 2-keto-3-deoxyoctonic acid-(alpha 2----6)-D-glucosamine analogs of lipid A.
    Infection and immunity, 1987, Volume: 55, Issue:9

    Topics: Animals; Glucosamine; Glucosephosphates; Lipid A; Lymphocyte Activation; Male; Mice; Rabbits; Shwartzman Phenomenon; Structure-Activity Relationship; Sugar Acids

1987
New synthetic immunomodulators combining a 4-O-phosphono-D-glucosamine derivative related to bacterial lipid A with 1-deoxy-N-acetylmuramoyl dipeptide analogs.
    Carbohydrate research, 1987, Sep-15, Volume: 167

    Topics: Adjuvants, Immunologic; Animals; Carbohydrate Conformation; Dipeptides; Glucosamine; Guinea Pigs; Hypersensitivity, Delayed; Indicators and Reagents; Lipid A; Magnetic Resonance Spectroscopy; Optical Rotation; Structure-Activity Relationship

1987
Synthesis of biologically active tetraacetyl-3-deoxy-D-manno-2-octulosonic acid(KDO)-(alpha 2----6)-D-glucosamine analogs of lipid A.
    Chemical & pharmaceutical bulletin, 1986, Volume: 34, Issue:5

    Topics: Glucosamine; Lipid A; Mitogens; Sugar Acids

1986
Mitogenic activity of chemically synthesized tetraacetyl-2-keto-3-deoxyoctonic acid-(alpha 2----6)-D-glucosamine analogues of lipid A.
    Chemical & pharmaceutical bulletin, 1986, Volume: 34, Issue:5

    Topics: Animals; Cells, Cultured; Glucosamine; Lipid A; Mice; Mice, Inbred C57BL; Mitogens; Sugar Acids

1986
Pseudomonas diminuta LPS with a new endotoxic lipid A structure.
    Biochemical and biophysical research communications, 1987, Feb-13, Volume: 142, Issue:3

    Topics: Animals; Chromatography, Thin Layer; Fatty Acids; Glucosamine; Glucose; Heptoses; Lipid A; Lipopolysaccharides; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Mice; Pseudomonas; Sugar Acids

1987
[Synthesis of lipid A analogs. Obtaining conjugates of 6-phosphate 2-desoxy-2-(3-hydroxymyristoyl)amino-D-glucose with polymer carriers and their immunological properties].
    Bioorganicheskaia khimiia, 1985, Volume: 11, Issue:5

    Topics: Animals; Chemical Phenomena; Chemistry; Enzyme-Linked Immunosorbent Assay; Glucosamine; Haptens; Immunization; Lipid A; Myristic Acids; Polymers; Rabbits; Yersinia; Yersinia pseudotuberculosis Infections

1985
Characterization of the lipopolysaccharide from the nod mutant of Rhizobium trifolii.
    Acta microbiologica Polonica, 1983, Volume: 32, Issue:1

    Topics: Amino Acids; Genes, Bacterial; Glucosamine; Lipid A; Lipopolysaccharides; Mutation; Rhizobium; Sugar Acids

1983
Fatty acyl derivatives of glucosamine 1-phosphate in Escherichia coli and their relation to lipid A. Complete structure of A diacyl GlcN-1-P found in a phosphatidylglycerol-deficient mutant.
    The Journal of biological chemistry, 1983, Jun-25, Volume: 258, Issue:12

    Topics: Escherichia coli; Fatty Acids; Glucosamine; Glucosephosphates; Lipid A; Lipopolysaccharides; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mutation; Phosphatidylglycerols

1983
Chemical structure of the lipid A component of the lipopolysaccharide from a Proteus mirabilis Re-mutant.
    European journal of biochemistry, 1983, Dec-01, Volume: 137, Issue:1-2

    Topics: Amino Sugars; Chemical Phenomena; Chemistry; Fatty Acids; Glucosamine; Lipid A; Methylation; Mutation; Proteus mirabilis

1983
The lipopolysaccharide of a chloridazon-degrading bacterium.
    European journal of biochemistry, 1983, Dec-01, Volume: 137, Issue:1-2

    Topics: Bacteria; Chemical Phenomena; Chemistry; Chromatography, Gas; Colorimetry; Electrophoresis, Paper; Fatty Acids; Glucosamine; Herbicides; Hydroxy Acids; Lipid A; Lipopolysaccharides; Methylation; Pyridazines; Soil Microbiology

1983
Structural studies on the phosphate-free lipid A of Rhodomicrobium vannielii ATCC 17100.
    European journal of biochemistry, 1983, Dec-01, Volume: 137, Issue:1-2

    Topics: Amides; Chemical Phenomena; Chemistry; Concanavalin A; Dansyl Compounds; Fatty Acids; Gas Chromatography-Mass Spectrometry; Glucosamine; Lipid A; Magnetic Resonance Spectroscopy; Methylation; Oxidation-Reduction; Rhodospirillaceae

1983
Biological activities of chemically synthesized analogues of the nonreducing sugar moiety of lipid A.
    FEBS letters, 1984, Feb-27, Volume: 167, Issue:2

    Topics: Animals; Female; Glucosamine; Glycoproteins; Interferon Inducers; Limulus Test; Lipid A; Mice; Pyrogens; Rabbits; Structure-Activity Relationship; Tumor Necrosis Factor-alpha

1984
Lipid A of lipopolysaccharide from Escherichia coli K12 CR34.
    Biochimie, 1980, Volume: 62, Issue:2-3

    Topics: Chemical Phenomena; Chemistry; Escherichia coli; Glucosamine; Lipid A; Lipopolysaccharides; Magnetic Resonance Spectroscopy

1980
Incorporation of substrate cell lipid A components into the lipopolysaccharide of intraperiplasmically grown Bdellovibrio bacteriovorus.
    Journal of bacteriology, 1981, Volume: 147, Issue:3

    Topics: Bdellovibrio; Escherichia coli; Fatty Acids; Galactose; Glucosamine; Glucose; Lipid A; Lipopolysaccharides; Pseudomonas

1981
Compositional analysis of glucosaminyl(acyl)phosphatidylinositol accumulated in HeLa S3 cells.
    European journal of biochemistry, 1995, Oct-01, Volume: 233, Issue:1

    Topics: Chromatography, Agarose; Glucosamine; Glycosylphosphatidylinositols; HeLa Cells; Humans; Lipid A; Mass Spectrometry; Molecular Structure

1995
Lipid A and related compounds. XXIX. Synthesis of biologically active N-acylated L-asparagine-containing D-glucosamine derivatives structurally related to lipid A.
    Chemical & pharmaceutical bulletin, 1994, Volume: 42, Issue:12

    Topics: Animals; Cell Division; Glucosamine; In Vitro Techniques; Lipid A; Macrophages, Peritoneal; Magnetic Resonance Spectroscopy; Mice; Mitogens; Nitric Oxide; Spectrometry, Mass, Fast Atom Bombardment; Spectrophotometry, Infrared

1994
Structural characterization of the lipid A of Bordetella pertussis 1414 endotoxin.
    Journal of bacteriology, 1994, Volume: 176, Issue:16

    Topics: Bordetella pertussis; Chromatography, Thin Layer; Endotoxins; Fatty Acids; Glucosamine; Lipid A; Magnetic Resonance Spectroscopy; Mass Spectrometry; Spectrum Analysis

1994
Composition of 2,3-dihydroxy fatty acid-containing lipopolysaccharides from Legionella israelensis, Legionella maceachernii and Legionella micdadei.
    Microbiology (Reading, England), 1994, Volume: 140 ( Pt 6)

    Topics: Carbohydrate Conformation; Carbohydrate Sequence; Carbohydrates; Chemical Fractionation; Disaccharides; Electrophoresis, Polyacrylamide Gel; Fatty Acids; Glucosamine; Hydrolysis; Legionella; Lipid A; Lipopolysaccharides; Molecular Sequence Data; Species Specificity

1994
Predominant role of the substituents on the hydroxyl groups of 3-hydroxy fatty acids of non-reducing glucosamine in lipid A for the endotoxic and antagonistic activity.
    FEBS letters, 1994, Sep-12, Volume: 351, Issue:3

    Topics: Acetylation; Animals; Endotoxins; Fatty Acids; Female; Glucosamine; Hydroxyl Radical; Lipid A; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mitosis; Structure-Activity Relationship; Succinates; Succinic Acid

1994
New acyclic analogues of lipid A: synthesis of 4-phosphonoxybutyl and 3-phosphonoxypropyl glycosides of 2-amino-2-deoxy-D-glucose.
    Carbohydrate research, 1994, Jan-03, Volume: 251

    Topics: Glucosamine; Glycosides; Lipid A; Organophosphates

1994
Structure of lipid A component of Rhizobium leguminosarum bv. phaseoli lipopolysaccharide. Unique nonphosphorylated lipid A containing 2-amino-2-deoxygluconate, galacturonate, and glucosamine.
    The Journal of biological chemistry, 1994, May-20, Volume: 269, Issue:20

    Topics: Carbohydrate Conformation; Carbohydrate Sequence; Escherichia coli; Fatty Acids; Glucosamine; Hexuronic Acids; Lipid A; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Rhizobium leguminosarum; Spectrometry, Mass, Fast Atom Bombardment

1994
Synthesis of biologically active N-acylated L-serine-containing D-glucosamine-4-phosphate derivatives of lipid A.
    Chemical & pharmaceutical bulletin, 1993, Volume: 41, Issue:10

    Topics: Animals; Carbohydrate Sequence; Cell Division; Glucosamine; Glucosephosphates; Lipid A; Mice; Mice, Inbred C3H; Molecular Sequence Data; Phosphorylation; Serine; Spleen

1993
Legionella pneumophila growth restriction and cytokine production by murine macrophages activated by a novel Pseudomonas lipid A.
    Infection and immunity, 1994, Volume: 62, Issue:2

    Topics: Animals; Cytokines; Endotoxins; Glucosamine; In Vitro Techniques; Interleukin-1; Legionella pneumophila; Lipid A; Macrophage Activation; Macrophages, Peritoneal; Mice; Mice, Inbred A; Molecular Structure; Pseudomonas; Tumor Necrosis Factor-alpha

1994
An artificial glycoconjugate containing the bisphosphorylated glucosamine disaccharide backbone of lipid A binds lipid A monoclonal antibodies.
    Infection and immunity, 1993, Volume: 61, Issue:10

    Topics: Antibodies, Monoclonal; Disaccharides; Escherichia coli; Glucosamine; Glycoconjugates; In Vitro Techniques; Lipid A

1993
Structural characterization of the lipid A component of Helicobacter pylori rough- and smooth-form lipopolysaccharides.
    Journal of bacteriology, 1997, Volume: 179, Issue:20

    Topics: Ethanolamine; Fatty Acids; Glucosamine; Helicobacter pylori; Lipid A; Magnetic Resonance Spectroscopy; Mass Spectrometry; Methylation; Oligosaccharides; Phosphates

1997
Structural studies on the lipopolysaccharide from a rough strain of Ochrobactrum anthropi containing a 2,3-diamino-2,3-dideoxy-D-glucose disaccharide lipid A backbone.
    Carbohydrate research, 1998, Volume: 306, Issue:1-2

    Topics: Carbohydrate Sequence; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Glucosamine; Gram-Negative Aerobic Rods and Cocci; Hydrogen-Ion Concentration; Lipid A; Lipopolysaccharides; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Oligosaccharides

1998
Simultaneous determination of glucosamine and glucosamine 4-phosphate in Lipid A with high-performance anion-exchange chromatography (HPAEC).
    Carbohydrate research, 1998, Volume: 312, Issue:1-2

    Topics: Chromatography, High Pressure Liquid; Glucosamine; Glucosephosphates; Lipid A

1998
252Cf-plasma desorption mass spectrometry of unmodified lipid A: fragmentation patterns and localization of fatty acids.
    Rapid communications in mass spectrometry : RCM, 1999, Volume: 13, Issue:22

    Topics: Escherichia coli; Fatty Acids; Glucosamine; Hydrogen-Ion Concentration; Hydrolysis; Lipid A; Lipopolysaccharides; Mass Spectrometry; Molecular Structure; Neisseria meningitidis; Salmonella; Static Electricity; Yersinia enterocolitica

1999
Structure of the lipid A of Bordetella hinzii ATCC 51730.
    Rapid communications in mass spectrometry : RCM, 2000, Volume: 14, Issue:7

    Topics: Acylation; Bordetella; Bordetella bronchiseptica; Bordetella pertussis; Carbohydrate Conformation; Chromatography, Gel; Chromatography, Thin Layer; Electrophoresis, Polyacrylamide Gel; Esters; Fatty Acids; Gas Chromatography-Mass Spectrometry; Glucosamine; Lipid A; Magnetic Resonance Spectroscopy; Mass Spectrometry; Models, Molecular; Silicon Dioxide; Species Specificity; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2000
Two-dimensional NMR spectroscopy and structures of six lipid A species from Rhizobium etli CE3. Detection of an acyloxyacyl residue in each component and origin of the aminogluconate moiety.
    The Journal of biological chemistry, 2000, Sep-08, Volume: 275, Issue:36

    Topics: Carbohydrate Conformation; Carbohydrate Sequence; Chromatography, Thin Layer; Gluconates; Glucosamine; Gram-Negative Bacteria; Hydroxybutyrates; Lipid A; Molecular Conformation; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Rhizobium

2000
Helicobacter mustelae lipid A structure differs from that of Helicobacter pylori.
    FEBS letters, 2001, Jun-15, Volume: 499, Issue:1-2

    Topics: Animals; Carbohydrate Conformation; Fatty Acids; Ferrets; Glucosamine; Helicobacter; Helicobacter pylori; Lipid A; Lipopolysaccharides; Magnetic Resonance Spectroscopy; Myristates; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2001
Practical stereoselective synthesis of alpha-linked C-glucosamine propionic acid esters: conversion to GLA-60 derivatives.
    Carbohydrate research, 2002, Feb-05, Volume: 337, Issue:2

    Topics: Esters; Glucosamine; Glycosylation; Humans; Lipid A; Lipopolysaccharides; Propionates; Stereoisomerism; Tumor Necrosis Factor-alpha; U937 Cells

2002
Biophysical characterization of triacyl monosaccharide lipid a partial structures in relation to bioactivity.
    Biophysical journal, 2002, Volume: 83, Issue:1

    Topics: Animals; Biophysical Phenomena; Biophysics; CHO Cells; Cricetinae; Cytokines; Dose-Response Relationship, Drug; Drosophila Proteins; Glucosamine; Glycolipids; Horseshoe Crabs; Humans; Leukocytes, Mononuclear; Light; Lipid A; Lipopolysaccharide Receptors; Membrane Glycoproteins; Models, Biological; Models, Chemical; Monosaccharides; Protein Conformation; Receptors, Cell Surface; Scattering, Radiation; Spectroscopy, Fourier Transform Infrared; Temperature; Toll-Like Receptors; Tumor Necrosis Factor-alpha; X-Ray Diffraction

2002
Lipid A structure of Pseudoalteromonas haloplanktis TAC 125: use of electrospray ionization tandem mass spectrometry for the determination of fatty acid distribution.
    Journal of mass spectrometry : JMS, 2002, Volume: 37, Issue:5

    Topics: Fatty Acids; Glucosamine; Gram-Negative Bacteria; Lipid A; Lipopolysaccharides; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2002
An outer membrane enzyme that generates the 2-amino-2-deoxy-gluconate moiety of Rhizobium leguminosarum lipid A.
    The Journal of biological chemistry, 2003, Apr-04, Volume: 278, Issue:14

    Topics: Carbon Radioisotopes; Escherichia coli; Glucosamine; Glycolipids; In Vitro Techniques; Lipid A; Membrane Proteins; Oxidation-Reduction; Rhizobium leguminosarum; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substrate Specificity

2003
Origin of the 2-amino-2-deoxy-gluconate unit in Rhizobium leguminosarum lipid A. Expression cloning of the outer membrane oxidase LpxQ.
    The Journal of biological chemistry, 2003, Apr-04, Volume: 278, Issue:14

    Topics: Amino Acid Sequence; Anaerobiosis; Bacterial Outer Membrane Proteins; Cloning, Molecular; Deoxyribonuclease HindIII; Escherichia coli; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Glucosamine; In Vitro Techniques; Lipid A; Mass Spectrometry; Molecular Sequence Data; Oxidoreductases; Phosphotransferases (Alcohol Group Acceptor); Recombinant Proteins; Rhizobium leguminosarum

2003
PURIFICATION AND CHARACTERIZATION OF THE LIPID A COMPONENT OF THE LIPOPOLYSACCHARIDES FROM ESCHERICHIA COLI.
    Biochemistry, 1964, Volume: 3

    Topics: Borates; Chromatography; Escherichia coli; Fatty Acids; Glucosamine; Lipid A; Lipids; Lipopolysaccharides; Polysaccharides; Polysaccharides, Bacterial; Research

1964
Physicochemical characterization of the endotoxins from Coxiella burnetii strain Priscilla in relation to their bioactivities.
    BMC biochemistry, 2004, Jan-12, Volume: 5

    Topics: Chromatography, Gas; Coxiella; Disaccharides; Dose-Response Relationship, Drug; Endotoxins; Fatty Acids; Gas Chromatography-Mass Spectrometry; Glucosamine; Humans; Leukocytes, Mononuclear; Lipid A; Lipopolysaccharides; Liposomes; Molecular Conformation; Phase Transition; Salmonella; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Structure-Activity Relationship; Tumor Necrosis Factor-alpha; X-Ray Diffraction

2004
Characterization of Mesorhizobium huakuii lipid A containing both D-galacturonic acid and phosphate residues.
    European journal of biochemistry, 2004, Volume: 271, Issue:7

    Topics: Alphaproteobacteria; Gas Chromatography-Mass Spectrometry; Glucosamine; Hexuronic Acids; Hydrocarbons; Lipid A; Lipids; Magnetic Resonance Spectroscopy; Models, Chemical; Phosphates; Phosphorylation; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2004
Structure of lipid A from the marine gamma-proteobacterium Marinomonas vaga ATCC 27119T lipopolysaccharide.
    Biochemistry. Biokhimiia, 2004, Volume: 69, Issue:4

    Topics: Animals; Glucosamine; Hydrolysis; Lipid A; Lipopolysaccharides; Oceanospirillaceae; Seawater

2004
A synthetic TLR4 antagonist has anti-inflammatory effects in two murine models of inflammatory bowel disease.
    Journal of immunology (Baltimore, Md. : 1950), 2005, May-15, Volume: 174, Issue:10

    Topics: Adjuvants, Immunologic; Animals; Anti-Inflammatory Agents, Non-Steroidal; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caproates; Cells, Cultured; Colitis; Dextran Sulfate; Disease Models, Animal; Female; Glucosamine; HeLa Cells; Humans; Inflammatory Bowel Diseases; Lipid A; Lipopolysaccharides; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Knockout; Monocytes; Receptors, Immunologic; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha

2005
A matrix-assisted laser desorption/ionization mass spectrometry approach to the lipid A from Mesorhizobium loti.
    Rapid communications in mass spectrometry : RCM, 2006, Volume: 20, Issue:14

    Topics: Chromatography, Thin Layer; Fatty Acids; Gas Chromatography-Mass Spectrometry; Glucosamine; Hexuronic Acids; Lipid A; Proteobacteria; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2006
Structural features of lipid A of Piscirickettsia salmonis, the etiological agent of the salmonid rickettsial septicemia.
    Acta virologica, 2007, Volume: 51, Issue:4

    Topics: Acylation; Amino Sugars; Animals; Gas Chromatography-Mass Spectrometry; Glucosamine; Lipid A; Molecular Structure; Myristic Acids; Phosphates; Piscirickettsia; Salmonidae; Tandem Mass Spectrometry

2007
Glucosamine found as a substituent of both phosphate groups in Bordetella lipid A backbones: role of a BvgAS-activated ArnT ortholog.
    Journal of bacteriology, 2008, Volume: 190, Issue:12

    Topics: Amino Acids; Bordetella bronchiseptica; Chromatography, Gas; Chromatography, Thin Layer; Fatty Acids; Glucosamine; Lipid A; Lipopolysaccharides; Models, Molecular; Molecular Structure; Phosphorylation; Reverse Transcriptase Polymerase Chain Reaction; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2008
Induction of innate immunity by lipid A mimetics increases survival from pneumonic plague.
    Microbiology (Reading, England), 2008, Volume: 154, Issue:Pt 7

    Topics: Animals; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Glucosamine; Humans; Immunity, Innate; Lipid A; Lung; Mice; Mice, Inbred BALB C; Mice, Knockout; Organophosphorus Compounds; Plague; Specific Pathogen-Free Organisms; Time Factors; Toll-Like Receptor 4; Yersinia pestis

2008
Lipid A mimetics are potent adjuvants for an intranasal pneumonic plague vaccine.
    Vaccine, 2008, Oct-16, Volume: 26, Issue:44

    Topics: Adjuvants, Immunologic; Administration, Intranasal; Animals; Antibodies, Bacterial; Disease Models, Animal; Female; Glucosamine; Humans; Lipid A; Male; Mice; Mice, Inbred BALB C; Molecular Mimicry; Plague; Plague Vaccine; Rats; Rats, Sprague-Dawley; Toll-Like Receptor 4; Yersinia pestis

2008
The 'Ethereal' nature of TLR4 agonism and antagonism in the AGP class of lipid A mimetics.
    Bioorganic & medicinal chemistry letters, 2008, Oct-15, Volume: 18, Issue:20

    Topics: Animals; Chemistry, Pharmaceutical; Drug Design; Glucosamine; Glycolipids; Humans; Inhibitory Concentration 50; Lipid A; Lipids; Mice; Models, Biological; Models, Chemical; Monocytes; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha

2008
Structural characterization of Bordetella parapertussis lipid A.
    Journal of lipid research, 2009, Volume: 50, Issue:5

    Topics: Bordetella parapertussis; Esters; Fatty Acids; Glucosamine; Humans; Lipid A; Molecular Structure; Protein Conformation

2009
A sensitive liquid chromatography/mass spectrometry-based assay for quantitation of amino-containing moieties in lipid A.
    Rapid communications in mass spectrometry : RCM, 2009, Volume: 23, Issue:3

    Topics: Amino Sugars; Arabinose; Chromatography, Liquid; Ethanolamine; Francisella tularensis; Galactosamine; Glucosamine; Linear Models; Lipid A; Mass Spectrometry; Models, Chemical; Mutation; Reproducibility of Results; Salmonella typhi; Sensitivity and Specificity

2009
Structural prerequisites for endotoxic activity in the Limulus test as compared to cytokine production in mononuclear cells.
    Innate immunity, 2010, Volume: 16, Issue:1

    Topics: Animals; Bacterial Infections; Cells, Cultured; Cytokines; Endotoxins; Glucosamine; Horseshoe Crabs; Humans; Leukocytes, Mononuclear; Limulus Test; Lipid A; Lymphocyte Activation; Predictive Value of Tests; Protein Multimerization; Research Design

2010
Structure of compositionally simple lipopolysaccharide from marine synechococcus.
    Journal of bacteriology, 2009, Volume: 191, Issue:17

    Topics: Fatty Acids; Glucosamine; Glucose; Hexuronic Acids; Lipid A; Lipopolysaccharides; Molecular Structure; Phosphates; Rhamnose; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Synechococcus

2009
CD14-independent responses induced by a synthetic lipid A mimetic.
    European journal of immunology, 2010, Volume: 40, Issue:3

    Topics: Adjuvants, Immunologic; Animals; Biomimetics; Cell Line; Cytokines; Dendritic Cells; Glucosamine; Humans; Lipid A; Lipopolysaccharide Receptors; Lymphocyte Antigen 96; Mice; Mice, Inbred C57BL; Organophosphorus Compounds; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Toll-Like Receptor 4; Transfection

2010
Substitution of the Bordetella pertussis lipid A phosphate groups with glucosamine is required for robust NF-kappaB activation and release of proinflammatory cytokines in cells expressing human but not murine Toll-like receptor 4-MD-2-CD14.
    Infection and immunity, 2010, Volume: 78, Issue:5

    Topics: Animals; Bordetella pertussis; Cell Line; Cytokines; Glucosamine; Humans; Lipid A; Lipopolysaccharide Receptors; Lymphocyte Antigen 96; Macrophages; Mice; NF-kappa B; Phosphates; Toll-Like Receptor 4

2010
Altered linkage of hydroxyacyl chains in bacterial lipid A.
    The Journal of biological chemistry, 2010, Jul-09, Volume: 285, Issue:28

    Topics: Anti-Infective Agents; Campylobacter jejuni; Fatty Acids; Glucosamine; Humans; Lipid A; Lipopolysaccharides; Peptides; Temperature

2010
Structural modifications occurring in lipid A of Bordetella bronchiseptica clinical isolates as demonstrated by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
    Rapid communications in mass spectrometry : RCM, 2011, Apr-30, Volume: 25, Issue:8

    Topics: Animals; Bordetella bronchiseptica; Bordetella Infections; Glucosamine; Humans; Lipid A; Molecular Structure; Palmitic Acid; Rabbits; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2011
Selective TRIF-dependent signaling by a synthetic toll-like receptor 4 agonist.
    Science signaling, 2012, Feb-14, Volume: 5, Issue:211

    Topics: Active Transport, Cell Nucleus; Adaptor Proteins, Vesicular Transport; Blotting, Western; Cell Line; Cell Line, Tumor; Cell Nucleus; Cells, Cultured; Chemokine CCL5; Chemokine CXCL10; Dose-Response Relationship, Drug; Endocytosis; Glucosamine; HEK293 Cells; Humans; Hydrazones; Lipid A; Molecular Structure; Mutation; Myeloid Differentiation Factor 88; NF-kappa B; Organophosphorus Compounds; Signal Transduction; Stereoisomerism; Toll-Like Receptor 4; Transfection; Tumor Necrosis Factor-alpha

2012
Complete Bordetella avium, Bordetella hinzii and Bordetella trematum lipid A structures and genomic sequence analyses of the loci involved in their modifications.
    Innate immunity, 2014, Volume: 20, Issue:6

    Topics: Amino Acid Sequence; Bordetella; Bordetella avium; Endotoxins; Fatty Acids; Genome, Bacterial; Glucosamine; Humans; Hydrolysis; Lipid A; Lipopolysaccharides; Molecular Sequence Data; Phosphates

2014
Enzymatic modification of lipid A by ArnT protects Bordetella bronchiseptica against cationic peptides and is required for transmission.
    Infection and immunity, 2014, Volume: 82, Issue:2

    Topics: Animals; Antimicrobial Cationic Peptides; Bordetella bronchiseptica; Bordetella Infections; Disease Models, Animal; Glucosamine; Hexosyltransferases; Lipid A; Mice; Mice, Inbred C57BL; Microbial Viability

2014
Analysis of Pseudomonas aeruginosa PAO1 lipid A changes during the interaction with model organism, Caenorhabditis elegans.
    Lipids, 2014, Volume: 49, Issue:6

    Topics: Animals; Biofilms; Caenorhabditis elegans; Cells, Cultured; Epithelium, Corneal; Glucosamine; Host-Pathogen Interactions; Humans; Immunity, Innate; Lipid A; Lipid Metabolism; Magnetic Resonance Spectroscopy; O Antigens; Pseudomonas aeruginosa; Spectroscopy, Fourier Transform Infrared; Transcriptome

2014
Bordetella pertussis lipid A glucosamine modification confers resistance to cationic antimicrobial peptides and increases resistance to outer membrane perturbation.
    Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:8

    Topics: Amino Acid Sequence; Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Bordetella pertussis; Cell Membrane; Drug Resistance, Bacterial; Glucosamine; Lipid A; Microbial Sensitivity Tests; Molecular Sequence Data; Polymyxins

2014
Anti-endotoxic activity and structural basis for human MD-2·TLR4 antagonism of tetraacylated lipid A mimetics based on βGlcN(1↔1)αGlcN scaffold.
    Innate immunity, 2015, Volume: 21, Issue:5

    Topics: Binding Sites; Cell Line; Cytokines; Dendritic Cells; Endotoxins; Epithelial Cells; Escherichia coli; Glucosamine; Humans; Immunity, Innate; Lipid A; Lipopolysaccharides; Lymphocyte Antigen 96; Molecular Conformation; Signal Transduction; Toll-Like Receptor 4

2015
Characterization of TRIF selectivity in the AGP class of lipid A mimetics: role of secondary lipid chains.
    Bioorganic & medicinal chemistry letters, 2015, Feb-01, Volume: 25, Issue:3

    Topics: Adaptor Proteins, Vesicular Transport; Binding Sites; Biocompatible Materials; Cytokines; Glucosamine; HEK293 Cells; Humans; Lipid A; Molecular Docking Simulation; Myeloid Differentiation Factor 88; NF-kappa B; Organophosphorus Compounds; Protein Binding; Protein Structure, Tertiary; Signal Transduction; Toll-Like Receptor 4

2015
Chemical synthesis of Burkholderia Lipid A modified with glycosyl phosphodiester-linked 4-amino-4-deoxy-β-L-arabinose and its immunomodulatory potential.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2015, Mar-02, Volume: 21, Issue:10

    Topics: Amino Sugars; Anti-Bacterial Agents; Arabinose; Bacterial Proteins; Burkholderia; Escherichia coli; Glucosamine; Glycolipids; Humans; Lipid A; Lipopolysaccharides; Protein Conformation; Structure-Activity Relationship

2015
Bordetella pertussis Lipid A Recognition by Toll-like Receptor 4 and MD-2 Is Dependent on Distinct Charged and Uncharged Interfaces.
    The Journal of biological chemistry, 2015, May-22, Volume: 290, Issue:21

    Topics: Amino Acids; Animals; Blotting, Western; Bordetella pertussis; Cells, Cultured; Glucosamine; HEK293 Cells; Host Specificity; Humans; Immunity, Innate; Lipid A; Lymphocyte Antigen 96; Mice; Mutagenesis, Site-Directed; Mutation; Protein Conformation; Signal Transduction; Toll-Like Receptor 4

2015
Crystal structure of A. aeolicus LpxC with bound product suggests alternate deacetylation mechanism.
    Proteins, 2015, Volume: 83, Issue:9

    Topics: Acetylation; Amidohydrolases; Bacteria; Bacterial Proteins; Biocatalysis; Catalytic Domain; Crystallography, X-Ray; Enzyme Inhibitors; Glucosamine; Lipid A; Models, Molecular; Molecular Structure; Protein Binding; Protein Structure, Tertiary; Quantum Theory; Substrate Specificity; Zinc

2015
Studies on lipid A isolated from Phyllobacterium trifolii PETP02
    Antonie van Leeuwenhoek, 2017, Volume: 110, Issue:11

    Topics: Fatty Acids; Glucosamine; Hexuronic Acids; Lipid A; Lipopolysaccharides; Magnetic Resonance Spectroscopy; Mesorhizobium; Metabolic Networks and Pathways; Phyllobacteriaceae; Sequence Homology, Amino Acid; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2017
Ex-vivo generation of drug-eluting islets improves transplant outcomes by inhibiting TLR4-Mediated NFkB upregulation.
    Biomaterials, 2018, Volume: 159

    Topics: Animals; Cell Line, Tumor; Cell Survival; Diabetes Mellitus; Glucosamine; Inflammation; Islets of Langerhans; Islets of Langerhans Transplantation; Lipid A; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Sulfonamides; Toll-Like Receptor 4

2018
Bordetella bronchiseptica Glycosyltransferase Core Mutants Trigger Changes in Lipid A Structure.
    Journal of the American Society for Mass Spectrometry, 2019, Volume: 30, Issue:9

    Topics: Bacterial Proteins; Bordetella bronchiseptica; Diphosphates; Glucosamine; Glycosyltransferases; Lipid A; Mutation; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tandem Mass Spectrometry

2019
Self-Adjuvanting Cancer Vaccines from Conjugation-Ready Lipid A Analogues and Synthetic Long Peptides.
    Journal of medicinal chemistry, 2020, 10-22, Volume: 63, Issue:20

    Topics: Adjuvants, Immunologic; Animals; Cancer Vaccines; Cytokines; Dendritic Cells; Glucosamine; Immunoglobulin G; Ligands; Lipid A; Lymphocyte Activation; Mice; Organophosphorus Compounds; Ovalbumin; Peptide Fragments; T-Lymphocytes; Toll-Like Receptor 4; Vaccines, Conjugate

2020