glucaric acid has been researched along with saccharolactone in 56 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (26.79) | 18.7374 |
| 1990's | 11 (19.64) | 18.2507 |
| 2000's | 6 (10.71) | 29.6817 |
| 2010's | 24 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bickel, MH; Gigon, PL | 1 |
| Martin, L; Parke, DV; Symons, AM; Wade, A | 1 |
| Ball, LM; Gustafsson, BE; Gustafsson, JA; Kohan, MJ; Lewtas, J; Rafter, JJ | 1 |
| Arend, R; Gourley, GR; Gourley, MF; Palta, M | 1 |
| Ho, KJ; Macfadyen, A | 1 |
| Downie, AA; Dwivedi, C; Webb, TE | 1 |
| Brambilla, P; Colombo, L; Crespi, C; Marocchi, A; Mocarelli, P; Mondonico, A; Tramacere, P | 1 |
| Hanausek-Walaszek, M; Walaszek, Z; Webb, TE | 1 |
| Nakayama, F; Oyabu, H; Tabata, M | 1 |
| Ho, KJ; Ho, LH; Ho, YC | 1 |
| Malejka-Giganti, D; Ryzewski, CN | 1 |
| Fujita, M; Makita, A; Oikawa, K; Taniguchi, N | 1 |
| Herd, JK; Mayberry, WR; Snell, RL | 1 |
| Ho, KJ; Ho, LH | 1 |
| Jung, K; Scholz, D; Schreiber, G | 1 |
| Endo, M; Izumi, J; Kato, I; Kojima, K; Nakamura, T; Shibata, S; Takagaki, K | 1 |
| Calabrese, EJ; Sacco, C | 1 |
| Calabrese, EJ; McEwen, WE; Sacco, C | 1 |
| Brunelle, FM; Verbeeck, RK | 3 |
| Diwu, Z; Herzenberg, LA; Lorincz, M; Nolan, GP; Roederer, M | 1 |
| Adams, AK; Hanausek, M; Kilgore, J; Narog, M; Sherman, U; Szemraj, J; Walaszek, Z | 1 |
| Hong, SK; Rankin, GO | 1 |
| Bánhegyi, G; Braun, L; Csala, M; El Koulali, K; Kardon, T; Mandl, J | 1 |
| BOYLAND, E; WALLACE, DM | 1 |
| Bhalla-Sarin, N; Bhomkar, P; Jain, S; Prakash, S; Sudan, C | 1 |
| Bald, E; Glowacki, R; Nowak, P; Olas, B; Saluk-Juszczak, J; Wachowicz, B | 1 |
| Olas, B; Saluk-Juszczak, J; Wachowicz, B | 1 |
| Nowak, P; Olas, B; Saluk-Juszczak, J; Staroń, A; Wachowicz, B | 1 |
| Court, MH; Oleson, L | 1 |
| Hanausek, M; Kiliańska, ZM; Walaszek, Z; Zółtaszek, R | 1 |
| Hanausek, M; Kowalczyk, MC; Kowalczyk, P; Narog, M; Slaga, TJ; Spears, E; Walaszek, Z; Yoshimi, N; Zoltaszek, R | 1 |
| Bhattacharya, S; Gachhui, R; Manna, P; Sil, PC | 2 |
| Duarte, J; Dueñas, M; Galindo, P; González-Manzano, S; Jimenez, R; Menendez, C; Moreno, L; Perez-Vizcaino, F; Rodríguez-Gómez, I; Santos-Buelga, C; Zarzuelo, MJ | 1 |
| Bhattacharya, S; Rashid, K; Sil, PC | 1 |
| Duarte, J; Dueñas, M; Galindo, P; González-Manzano, S; Jiménez, R; Menéndez, C; Pérez-Vizcaíno, F; Rodriguez-Gómez, I; Santos-Buelga, C; Tamargo, J; Vargas, F | 1 |
| Hu, M; Liu, Z; Xia, B; Ye, L; Zheng, Z; Zhou, Q | 1 |
| Bhattacharya, S; Gachhui, R; Sil, PC | 1 |
| Almilaji, A; Elvira, B; Föller, M; Lang, F; Munoz, C; Pakladok, T; Seebohm, G; Shumilina, E; Voelkl, J | 1 |
| Ji, B; Tian, W; Wang, R; Wang, Y; Wu, W; Yang, Z; Zhang, D | 1 |
| Eibl, G; Go, VL; Lu, QY; Zhang, L | 1 |
| Ali, M; Ambreen, N; Choudhary, MI; Karim, A; Khan, KM; Mansoor, S; Morales, GA; Naureen, S; Perveen, S; Rustamova, X; Saied, S | 1 |
| Choudhary, MI; Fakhri, MI; Hussain, S; Khan, KM; Perveen, S; Saad, SM; Shaikh, NN | 1 |
| Liu, A; Wei, J; Xie, B; Ye, X; Zhan, X | 1 |
| Gong, T; Wang, H; Xie, B; Zhang, N; Zhang, Z; Zou, H | 1 |
| Ahmed, M; Ajay, SS; Almilaji, A; Elvira, B; Honisch, S; Hosseinzadeh, Z; Lang, F; Liu, G; Munoz, C; Sopjani, M | 1 |
| Dai, P; Hu, M; Li, Q; Liu, Z; Lu, L; Luo, F; Wang, L; Wang, X; Wang, Y; Zhu, L | 1 |
| Bhattacharya, D; Bhattacharya, S; Chakraborty, W; Chakravorty, S; Chatzinotas, A; Gachhui, R | 1 |
| Liu, Y; Shao, J; Son, Y; Wang, H; Xie, B; Zou, H | 1 |
| Amiot, MJ; Dangles, O; Meyer, G; Obert, P; Pechère, L; Peyrol, J; Riva, C | 1 |
| Argikar, UA | 1 |
| Biernat, KA; Creekmore, BC; Liu, J; Pellock, SJ; Redinbo, MR; Stewart, LJ; Torres-Rivera, D; Tripathy, A; Walton, WG; Xu, Y | 1 |
| Liu, A; Sun, S; Xie, B; Yang, W; Zhou, G; Zou, S | 1 |
| Abrams, G; Adolfsson, E; Agarwal, PK; Akkan, AG; Al Alhareth, NS; Alves, VGL; Armentano, R; Bahroos, E; Baig, M; Baldridge, KK; Barman, S; Bartolucci, C; Basit, A; Bertoli, SV; Bian, L; Bigatti, G; Bobenko, AI; Boix, PP; Bokulic, T; Bolink, HJ; Borowiec, J; Bulski, W; Burciaga, J; Butt, NS; Cai, AL; Campos, AM; Cao, G; Cao, Y; Čapo, I; Caruso, ML; Chao, CT; Cheatum, CM; Chelminski, K; Chen, AJW; Chen, C; Chen, CH; Chen, D; Chen, G; Chen, H; Chen, LH; Chen, R; Chen, RX; Chen, X; Cherdtrakulkiat, R; Chirvony, VS; Cho, JG; Chu, K; Ciurlino, D; Coletta, S; Contaldo, G; Crispi, F; Cui, JF; D'Esposito, M; de Biase, S; Demir, B; Deng, W; Deng, Z; Di Pinto, F; Domenech-Ximenos, B; Dong, G; Drácz, L; Du, XJ; Duan, LJ; Duan, Y; Ekendahl, D; Fan, W; Fang, L; Feng, C; Followill, DS; Foreman, SC; Fortunato, G; Frew, R; Fu, M; Gaál, V; Ganzevoort, W; Gao, DM; Gao, X; Gao, ZW; Garcia-Alvarez, A; Garza, MS; Gauthier, L; Gazzaz, ZJ; Ge, RS; Geng, Y; Genovesi, S; Geoffroy, V; Georg, D; Gigli, GL; Gong, J; Gong, Q; Groeneveld, J; Guerra, V; Guo, Q; Guo, X; Güttinger, R; Guyo, U; Haldar, J; Han, DS; Han, S; Hao, W; Hayman, A; He, D; Heidari, A; Heller, S; Ho, CT; Ho, SL; Hong, SN; Hou, YJ; Hu, D; Hu, X; Hu, ZY; Huang, JW; Huang, KC; Huang, Q; Huang, T; Hwang, JK; Izewska, J; Jablonski, CL; Jameel, T; Jeong, HK; Ji, J; Jia, Z; Jiang, W; Jiang, Y; Kalumpha, M; Kang, JH; Kazantsev, P; Kazemier, BM; Kebede, B; Khan, SA; Kiss, J; Kohen, A; Kolbenheyer, E; Konai, MM; Koniarova, I; Kornblith, E; Krawetz, RJ; Kreouzis, T; Kry, SF; Laepple, T; Lalošević, D; Lan, Y; Lawung, R; Lechner, W; Lee, KH; Lee, YH; Leonard, C; Li, C; Li, CF; Li, CM; Li, F; Li, J; Li, L; Li, S; Li, X; Li, Y; Li, YB; Li, Z; Liang, C; Lin, J; Lin, XH; Ling, M; Link, TM; Liu, HH; Liu, J; Liu, M; Liu, W; Liu, YP; Lou, H; Lu, G; Lu, M; Lun, SM; Ma, Z; Mackensen, A; Majumdar, S; Martineau, C; Martínez-Pastor, JP; McQuaid, JR; Mehrabian, H; Meng, Y; Miao, T; Miljković, D; Mo, J; Mohamed, HSH; Mohtadi, M; Mol, BWJ; Moosavi, L; Mosdósi, B; Nabu, S; Nava, E; Ni, L; Novakovic-Agopian, T; Nyamunda, BC; Nyul, Z; Önal, B; Özen, D; Özyazgan, S; Pajkrt, E; Palazon, F; Park, HW; Patai, Á; Patai, ÁV; Patzke, GR; Payette, G; Pedoia, V; Peelen, MJCS; Pellitteri, G; Peng, J; Perea, RJ; Pérez-Del-Rey, D; Popović, DJ; Popović, JK; Popović, KJ; Posecion, L; Povall, J; Prachayasittikul, S; Prachayasittikul, V; Prat-González, S; Qi, B; Qu, B; Rakshit, S; Ravelli, ACJ; Ren, ZG; Rivera, SM; Salo, P; Samaddar, S; Samper, JLA; Samy El Gendy, NM; Schmitt, N; Sekerbayev, KS; Sepúlveda-Martínez, Á; Sessolo, M; Severi, S; Sha, Y; Shen, FF; Shen, X; Shen, Y; Singh, P; Sinthupoom, N; Siri, S; Sitges, M; Slovak, JE; Solymosi, N; Song, H; Song, J; Song, M; Spingler, B; Stewart, I; Su, BL; Su, JF; Suming, L; Sun, JX; Tantimavanich, S; Tashkandi, JM; Taurbayev, TI; Tedgren, AC; Tenhunen, M; Thwaites, DI; Tibrewala, R; Tomsejm, M; Triana, CA; Vakira, FM; Valdez, M; Valente, M; Valentini, AM; Van de Winckel, A; van der Lee, R; Varga, F; Varga, M; Villarino, NF; Villemur, R; Vinatha, SP; Vincenti, A; Voskamp, BJ; Wang, B; Wang, C; Wang, H; Wang, HT; Wang, J; Wang, M; Wang, N; Wang, NC; Wang, Q; Wang, S; Wang, X; Wang, Y; Wang, Z; Wen, N; Wesolowska, P; Willis, M; Wu, C; Wu, D; Wu, L; Wu, X; Wu, Z; Xia, JM; Xia, X; Xia, Y; Xiao, J; Xiao, Y; Xie, CL; Xie, LM; Xie, S; Xing, Z; Xu, C; Xu, J; Yan, D; Yan, K; Yang, S; Yang, X; Yang, XW; Ye, M; Yin, Z; Yoon, N; Yoon, Y; Yu, H; Yu, K; Yu, ZY; Zhang, B; Zhang, GY; Zhang, H; Zhang, J; Zhang, M; Zhang, Q; Zhang, S; Zhang, W; Zhang, X; Zhang, Y; Zhang, YW; Zhang, Z; Zhao, D; Zhao, F; Zhao, P; Zhao, W; Zhao, Z; Zheng, C; Zhi, D; Zhou, C; Zhou, FY; Zhu, D; Zhu, J; Zhu, Q; Zinyama, NP; Zou, M; Zou, Z | 1 |
3 review(s) available for glucaric acid and saccharolactone
| Article | Year |
|---|---|
[The biological role of D-glucaric acid and its derivatives: potential use in medicine].
Topics: Animals; Apoptosis; Glucaric Acid; Glucuronidase; Humans; Neoplasms; Oxidative Stress; Risk Factors | 2008 |
Saccharolactone: The History, the Myth, and the Practice.
Topics: Glucaric Acid; Glucuronosyltransferase; Humans; Microsomes | 2018 |
Topics: Acetylcholine; Acinetobacter baumannii; Actinobacteria; Action Potentials; Adalimumab; Adaptation, Physiological; Adipates; Administration, Oral; Adolescent; Adrenal Glands; Adsorption; Adult; Aged; Aged, 80 and over; Aging; AIDS-Related Opportunistic Infections; Aldosterone; Amino Acids; Ammonia; Amoxicillin; AMP-Activated Protein Kinases; Animals; Antacids; Anti-Bacterial Agents; Antineoplastic Agents; Antirheumatic Agents; Apgar Score; Area Under Curve; ARNTL Transcription Factors; Arterial Pressure; Arthritis, Juvenile; Athletes; Attention; Biodegradation, Environmental; Biofilms; Biofuels; Biological Therapy; Biomass; Biomimetic Materials; Bioreactors; Birth Weight; Bismuth; Blood Flow Velocity; Bone and Bones; Brain Injuries, Traumatic; Calcium; Calcium Channels; Capsaicin; Carbon; Carcinoma, Hepatocellular; Cardiomegaly, Exercise-Induced; Cartilage; Cartilage, Articular; Case-Control Studies; Catalysis; Cats; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Death; Cell Differentiation; Cell Line, Tumor; Cell Membrane; Charcoal; Chemokine CCL2; Child; Child, Preschool; Chondrogenesis; Chronic Disease; Circadian Clocks; Circadian Rhythm Signaling Peptides and Proteins; Clarithromycin; Coccidioides; Coccidioidomycosis; Cognitive Behavioral Therapy; Coinfection; Color; Coloring Agents; Computer Simulation; Computers, Molecular; Consensus; Corticosterone; Cyclic AMP Response Element-Binding Protein; Cytochrome P-450 Enzyme System; Death, Sudden, Cardiac; Density Functional Theory; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Dialysis Solutions; Disease Models, Animal; Dogs; Dopamine Agonists; Dose-Response Relationship, Drug; Doxorubicin; Drug Administration Schedule; Drug Resistance, Bacterial; Drug Therapy, Combination; Electrocardiography; Electrocardiography, Ambulatory; Electrolytes; Endocardium; Endocrine Disruptors; Endocytosis; Endoscopy, Gastrointestinal; Escherichia coli Proteins; Esters; Evolution, Molecular; Executive Function; Feasibility Studies; Female; Ferric Compounds; Fluorescence; Fluorescent Dyes; Fluorine Radioisotopes; Frailty; Free Radical Scavengers; Gabapentin; Geriatric Assessment; Glucaric Acid; Glucocorticoids; Glucose; Glucose Metabolism Disorders; Halogenated Diphenyl Ethers; Heart Rate; Heart Ventricles; HEK293 Cells; Helicobacter Infections; Helicobacter pylori; Hep G2 Cells; Hepatocytes; Humans; Hungary; Hydrogen Sulfide; Hydrogen-Ion Concentration; Immunologic Factors; Immunomodulation; Immunosuppressive Agents; Independent Living; Indocyanine Green; Infant; Infant Formula; Infant Mortality; Infant, Newborn; Infant, Newborn, Diseases; Inflorescence; Insulin Resistance; Insulins; International Agencies; Iron; Isotonic Solutions; Kidney Failure, Chronic; Kinetics; Lactones; Leukocytes, Mononuclear; Liver Neoplasms; Macular Edema; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Magnetosomes; Male; Medical Audit; Mesenchymal Stem Cells; Metabolic Syndrome; Metformin; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Nude; Middle Aged; Molecular Conformation; Molecular Targeted Therapy; Motor Activity; Multiple Sclerosis; Mycophenolic Acid; Netherlands; Neuropsychological Tests; Nuclear Energy; Organs at Risk; Osteoarthritis; Osteoarthritis, Hip; Oxidation-Reduction; Palladium; Pericardium; Perinatal Death; Peritoneal Dialysis; Phantoms, Imaging; Pharmaceutical Preparations; Phospholipids; Phosphorylation; Physical Conditioning, Human; Physical Endurance; Pilot Projects; Polyketides; Polymers; Positron-Emission Tomography; Postoperative Period; Potassium; Powders; Pramipexole; Predictive Value of Tests; Pregabalin; Pregnancy; Pregnancy Outcome; Protein Structure, Secondary; Proton Pump Inhibitors; Puberty; Pulmonary Circulation; Quality Assurance, Health Care; Quantum Dots; Radiometry; Radiotherapy Dosage; Radiotherapy Planning, Computer-Assisted; Radiotherapy, Intensity-Modulated; Rats, Sprague-Dawley; Receptors, CCR2; Receptors, Transferrin; Regeneration; Registries; Renal Insufficiency, Chronic; Reproducibility of Results; Research Design; Restless Legs Syndrome; Retina; Retinoid X Receptor alpha; Retrospective Studies; Rhenium; Risk Factors; RNA, Messenger; Severity of Illness Index; Sex Factors; Sodium; Sodium Fluoride; Solvents; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared; Stereoisomerism; Stroke; Structure-Activity Relationship; Tachycardia, Ventricular; Tetracycline; Tetrahydrofolate Dehydrogenase; Tetrahydronaphthalenes; Thermodynamics; Thiophenes; Time Factors; Tinidazole; Tomography, Optical Coherence; Tomography, X-Ray Computed; Topiramate; Toxoplasma; Toxoplasmosis, Cerebral; Transferrin; Treatment Outcome; Up-Regulation; Upper Extremity; Uremia; Uveitis; Vascular Remodeling; Ventricular Fibrillation; Ventricular Function, Left; Ventricular Function, Right; Ventricular Remodeling; Verapamil; Veterans; Visual Acuity; Vitrectomy; Water Pollutants, Chemical; Zea mays; Zirconium | 2019 |
53 other study(ies) available for glucaric acid and saccharolactone
| Article | Year |
|---|---|
Interference of UDP-glucuronyltransferase and beta-glucuronidase activity in rat liver microsomes at pH 7.5 with p-nitrophenol and p-nitrophenylglucuronide as substrates.
Topics: Animals; Glucaric Acid; Glucuronidase; Glucuronosyltransferase; Hydrogen-Ion Concentration; Kinetics; Lactones; Male; Microsomes, Liver; Nitrophenols; Rats | 1979 |
Metabolic oxidation of the ethynyl group in 4-ethynylbiphenyl.
Topics: Acetylene; Animals; Bile; Biphenyl Compounds; Chemical Phenomena; Chemistry; Feces; Female; Glucaric Acid; Lactones; Male; Mass Spectrometry; Neomycin; Oxidation-Reduction; Rabbits; Rats; Tetracycline | 1979 |
Formation of mutagenic urinary metabolites from 1-nitropyrene in germ-free and conventional rats: role of the gut flora.
Topics: Animals; Bacteria; Chromatography, High Pressure Liquid; Female; Germ-Free Life; Glucaric Acid; Glucuronidase; Intestines; Male; Mutagens; Pyrenes; Rats | 1991 |
The effect of saccharolactone on rat intestinal absorption of bilirubin in the presence of human breast milk.
Topics: Animals; Bilirubin; Glucaric Acid; Glucuronidase; Intestinal Absorption; Male; Milk, Human; Rats; Rats, Inbred Strains; Sugar Acids | 1989 |
D-glucaro-1,4-lactone: its excretion in the bile and urine and effect on the biliary secretion of beta-glucuronidase after oral administration in rats.
Topics: Administration, Oral; Animals; Bile; Glucaric Acid; Glucuronidase; Liver; Rats; Rats, Inbred Strains; Sugar Acids | 1989 |
Net glucuronidation in different rat strains: importance of microsomal beta-glucuronidase.
Topics: Animals; Bilirubin; Glucaric Acid; Glucuronidase; Glucuronosyltransferase; Male; Microsomes, Liver; Rats; Rats, Inbred F344; Rats, Inbred Strains; Rats, Inbred WF; Species Specificity; Time Factors | 1987 |
A new method for D-glucaric acid excretion measurement that is suitable for automated instruments.
Topics: Adolescent; Adult; Autoanalysis; Child; Child, Preschool; Female; Glucaric Acid; Glucuronidase; Humans; Male; Microchemistry; Microsomes, Liver; Reference Values; Software; Sugar Acids | 1988 |
Repression by sustained-release beta-glucuronidase inhibitors of chemical carcinogen-mediated induction of a marker oncofetal protein in rodents.
Topics: Administration, Oral; Animals; Antigens, Neoplasm; Calcium; Carcinogens; Delayed-Action Preparations; Female; Glucaric Acid; Glucuronidase; Potassium; Rats; Sugar Acids | 1988 |
Nonbacterial transformation of bilirubin in bile.
Topics: Bacteria; Bile; Bilirubin; Cholelithiasis; Gallbladder; Glucaric Acid; Glucuronidase; Humans; Hydrolysis; Liver; Neutrophils | 1987 |
Human hepatic beta-glucuronidase: an enzyme kinetic study.
Topics: Bilirubin; Glucaric Acid; Glucuronidase; Humans; Kinetics; Liver; Mathematics; Phenolphthaleins | 1985 |
A novel assay of glucuronidation of C- and N-hydroxylated metabolites of the carcinogen N-2-fluorenylacetamide.
Topics: 2-Acetylaminofluorene; Animals; Detergents; Female; Glucaric Acid; Glucuronates; Glucuronidase; Glucuronosyltransferase; Hydrolysis; Hydroxylation; In Vitro Techniques; Lactones; Microsomes, Liver; Rats | 1983 |
Cancer-associated alteration of beta-glucuronidase in human lung cancer: elevated activity and increased phosphorylation.
Topics: Adenocarcinoma; Alkaline Phosphatase; Carcinoma, Squamous Cell; Electrophoresis, Polyacrylamide Gel; Glucaric Acid; Glucuronidase; Glycoside Hydrolases; Hot Temperature; Humans; Isoelectric Focusing; Lung Neoplasms; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Phosphorylation | 1984 |
Synthesis of L-idaro-1,4-lactone, an inhibitor of alpha-L-idosiduronase.
Topics: Glucaric Acid; Glycoside Hydrolases; Humans; Iduronidase; Indicators and Reagents; Kinetics; Lactones; Male; Semen; Substrate Specificity; Sugar Acids | 1982 |
Determination of urinary beta-glucuronidase activity. Single-point versus enzyme kinetic measuring system.
Topics: Glucaric Acid; Glucuronidase; Humans; Hydrogen-Ion Concentration; Kinetics; Lactones | 1980 |
Improved determination of D-glucaric acid in urine.
Topics: Female; Glucaric Acid; Glucuronidase; Hot Temperature; Humans; Hydrogen-Ion Concentration; Lactones; Male; Sex Factors; Sugar Acids | 1981 |
A novel oligosaccharide, GlcA beta 1-4Xyl beta 1-(4-methylumbelliferone), synthesized by human cultured skin fibroblasts.
Topics: Benzoates; Benzoic Acid; Carbohydrate Sequence; Cells, Cultured; Fibroblasts; Glucaric Acid; Glucuronidase; Humans; Hymecromone; Mass Spectrometry; Molecular Sequence Data; Oligosaccharides; Skin | 1994 |
Selective inhibition of gastrointestinal beta-glucuronidase by poly(vinylbenzyl D-glucaro(1,4)lactonate). Part 2. Poly(vinylbenzyl D-glucaro(1,4) lactonate) in vitro inhibition studies.
Topics: Animals; Drug Stability; Escherichia coli; Glucaric Acid; Glucuronidase; In Vitro Techniques; Intestine, Small; Male; Mice; Polyvinyls; Structure-Activity Relationship | 1994 |
Selective inhibition of gastrointestinal beta-glucuronidase by polyvinylbenzyl D-glucaro(1,4)lactonate: attachment of D-glucaro(1,4)lactone to polyvinylbenzyl chloride.
Topics: Cesium; Digestive System; Glucaric Acid; Glucuronidase; Magnetic Resonance Spectroscopy; Polyvinyls; Spectrophotometry, Infrared | 1993 |
Glucuronidation of diflunisal by rat liver microsomes. Effect of microsomal beta-glucuronidase activity.
Topics: Animals; Detergents; Diflunisal; Glucaric Acid; Glucuronidase; Glucuronosyltransferase; Hydrogen-Ion Concentration; Kinetics; Male; Microsomes, Liver; Rats; Rats, Wistar | 1993 |
Enzyme-generated intracellular fluorescence for single-cell reporter gene analysis utilizing Escherichia coli beta-glucuronidase.
Topics: Animals; Base Sequence; beta-Galactosidase; Cells, Cultured; DNA Primers; Escherichia coli; Flow Cytometry; Fluoresceins; Genes, Reporter; Glucaric Acid; Glucuronidase; Hydrolysis; Indicators and Reagents; Mice; Microscopy, Fluorescence; Polymerase Chain Reaction; RNA, Messenger; Substrate Specificity; Temperature | 1996 |
Glucuronidation of diflunisal in liver and kidney microsomes of rat and man.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biotransformation; Chromatography, High Pressure Liquid; Diflunisal; Glucaric Acid; Glucuronates; Glucuronidase; Humans; In Vitro Techniques; Kidney; Kinetics; Male; Microsomes; Microsomes, Liver; Organ Specificity; Rats; Rats, Wistar; Species Specificity | 1996 |
Metabolism, uptake, and excretion of a D-glucaric acid salt and its potential use in cancer prevention.
Topics: Animals; Anticarcinogenic Agents; Bile; Biotransformation; Female; Gastric Mucosa; Glucaric Acid; Glucuronidase; Intestinal Absorption; Male; Rats; Rats, Sprague-Dawley; Tissue Distribution; Urine | 1997 |
Conjugation-deconjugation cycling of diflunisal via beta-glucuronidase catalyzed hydrolysis of its acyl glucuronide in the rat.
Topics: Animals; Bile; Catalysis; Diflunisal; Enzyme Inhibitors; Glucaric Acid; Glucuronates; Glucuronidase; Hydrolysis; Male; Microsomes, Liver; Rats; Rats, Wistar | 1997 |
Biotransformation of 2-chloroaniline in the Fischer 344 rat: identification of urinary metabolites.
Topics: Acetylation; Aniline Compounds; Animals; Arylsulfatases; Biotransformation; Chromatography, High Pressure Liquid; Feces; Glucaric Acid; Glucuronidase; Hydroxylation; Injections, Intraperitoneal; Male; Rats; Rats, Inbred F344 | 1998 |
Different induction of gulonolactone oxidase in aromatic hydrocarbon-responsive or -unresponsive mouse strains.
Topics: Animals; Ascorbic Acid; Cytochrome P-450 CYP1A1; Glucaric Acid; Glucuronates; Glucuronic Acid; Glucuronides; Glucuronosyltransferase; L-Gulonolactone Oxidase; Male; Methylcholanthrene; Mice; Mice, Inbred Strains; Microsomes, Liver; Receptors, Aryl Hydrocarbon; RNA, Messenger; Signal Transduction; Sugar Alcohol Dehydrogenases; Time Factors | 1999 |
Enzyme activity in relation to cancer: inhibition of urinary beta-glucuronidase of patients with cancer of the bladder by oral administration of 1:4-saccharolactone and related compounds.
Topics: Administration, Oral; Glucaric Acid; Glucose; Glucuronidase; Humans; Neoplasms; Urinary Bladder Neoplasms | 1957 |
Ubiquitous presence of beta-glucuronidase (GUS) in plants and its regulation in some model plants.
Topics: Benzyl Compounds; Cajanus; Cell Growth Processes; Gene Expression Regulation, Developmental; Gene Expression Regulation, Plant; Gibberellins; Glucaric Acid; Glucuronidase; Hydrogen-Ion Concentration; Kinetin; Plant Development; Plant Growth Regulators; Plants; Purines; Seedlings | 2006 |
Protective effects of D-glucaro 1,4-lactone against oxidative/nitrative modifications of plasma proteins.
Topics: Blood Proteins; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Glucaric Acid; Glutathione; Homocysteine; Humans; Hydrogen Peroxide; Molecular Weight; Nitrites; Oxidation-Reduction; Sulfhydryl Compounds; Tyrosine | 2007 |
D-glucaro 1,4-lactone and resveratrol as antioxidants in blood platelets.
Topics: Animals; Antioxidants; Arachidonic Acid; Biomarkers; Blood Platelets; Glucaric Acid; Humans; Lipid Peroxidation; Oxidative Stress; Platelet Aggregation; Protein Carbonylation; Rabbits; Resveratrol; Stilbenes; Superoxides; Thrombin | 2008 |
Protective effects of D-glucaro-1,4-lactone against oxidative modifications in blood platelets.
Topics: Analysis of Variance; Area Under Curve; Blood Platelets; Cardiovascular Diseases; Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Glucaric Acid; Humans; Hydrogen Peroxide; Lipid Peroxidation; Oxidation-Reduction; Oxidative Stress; Peroxynitrous Acid; Platelet Activation; Thiobarbituric Acid Reactive Substances | 2008 |
Effect of the beta-glucuronidase inhibitor saccharolactone on glucuronidation by human tissue microsomes and recombinant UDP-glucuronosyltransferases.
Topics: Animals; Cell Line; Dose-Response Relationship, Drug; Glucaric Acid; Glucuronidase; Glucuronides; Glucuronosyltransferase; Humans; Hydrogen-Ion Concentration; Hydrolysis; Insecta; Intestinal Mucosa; Kidney; Lung; Microsomes; Microsomes, Liver | 2008 |
Modulation of biomarkers related to tumor initiation and promotion in mouse skin by a natural β-glucuronidase inhibitor and its precursors.
Topics: 8-Hydroxy-2'-Deoxyguanosine; 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Administration, Topical; Animals; Anticarcinogenic Agents; Biomarkers; Carcinogens; Deoxyguanosine; Dermatitis, Contact; Female; Glucaric Acid; Glucuronates; Glucuronidase; HSP90 Heat-Shock Proteins; Hyperplasia; Inflammation Mediators; Interleukin-1alpha; Leukocyte Count; Mice; Mice, Inbred SENCAR; Neoplasms; Skin | 2011 |
D-saccharic acid-1,4-lactone ameliorates alloxan-induced diabetes mellitus and oxidative stress in rats through inhibiting pancreatic β-cells from apoptosis via mitochondrial dependent pathway.
Topics: Animals; Apoptosis; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Glucaric Acid; Insulin-Secreting Cells; Male; Membrane Potential, Mitochondrial; Mitochondria; Oxidative Stress; Random Allocation; Rats; Signal Transduction | 2011 |
Vascular deconjugation of quercetin glucuronide: the flavonoid paradox revealed?
Topics: Administration, Oral; Animals; Blood Pressure; Cardiovascular Agents; Glucaric Acid; Glucuronidase; Glycoproteins; In Vitro Techniques; Injections, Intravenous; Male; Mesenteric Arteries; Myocardial Contraction; Quercetin; Rats | 2011 |
Protective role of D-saccharic acid-1,4-lactone in alloxan induced oxidative stress in the spleen tissue of diabetic rats is mediated by suppressing mitochondria dependent apoptotic pathway.
Topics: Alloxan; Animals; Antioxidants; Apoptosis; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Drug Evaluation, Preclinical; Glucaric Acid; Glycated Hemoglobin; Hypoglycemic Agents; Insulin; Lactones; Lipid Peroxidation; Male; Membrane Potential, Mitochondrial; Mitochondria; Oxidative Stress; Protein Carbonylation; Rats; Reactive Oxygen Species; Spleen; Tumor Necrosis Factor-alpha | 2012 |
Glucuronidated quercetin lowers blood pressure in spontaneously hypertensive rats via deconjugation.
Topics: Administration, Oral; Animals; Blood Pressure; Glucaric Acid; Glucuronidase; In Vitro Techniques; Lactones; Male; Metabolic Detoxication, Phase II; Molecular Structure; Quercetin; Rats; Rats, Inbred SHR; Vasodilation | 2012 |
A novel local recycling mechanism that enhances enteric bioavailability of flavonoids and prolongs their residence time in the gut.
Topics: Animals; Anti-Bacterial Agents; Biological Availability; Caco-2 Cells; Flavanones; Gastrointestinal Tract; Glucaric Acid; Gluconates; Glucuronidase; Glucuronides; Humans; Intestinal Absorption; Jejunum; Kinetics; Lactase-Phlorizin Hydrolase; Lactones; Male; Rats; Rats, Sprague-Dawley; Recycling; Tandem Mass Spectrometry; Tissue Distribution | 2012 |
The prophylactic role of D-saccharic acid-1,4-lactone against hyperglycemia-induced hepatic apoptosis via inhibition of both extrinsic and intrinsic pathways in diabetic rats.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Down-Regulation; Glucaric Acid; Humans; Hyperglycemia; Lactones; Liver; Male; Oxidative Stress; Protective Agents; Rats; Reactive Oxygen Species; Signal Transduction | 2013 |
D-saccharic acid 1,4-lactone protects diabetic rat kidney by ameliorating hyperglycemia-mediated oxidative stress and renal inflammatory cytokines via NF-κB and PKC signaling.
Topics: Animals; Cytokines; Diabetes Mellitus, Experimental; Glucaric Acid; Hyperglycemia; Inflammation Mediators; Kidney; Lactones; Male; NF-kappa B; Oxidative Stress; Protective Agents; Protein Kinase C; Random Allocation; Rats; Signal Transduction | 2013 |
Klotho sensitivity of the hERG channel.
Topics: Animals; Cells, Cultured; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Glucaric Acid; Glucuronidase; Ion Channel Gating; Klotho Proteins; Lactones; Membrane Potentials; Oocytes; Patch-Clamp Techniques; RNA, Complementary; Xenopus | 2013 |
Hepatoprotective effects of kombucha tea: identification of functional strains and quantification of functional components.
Topics: Acetaminophen; Alanine Transaminase; Alkaline Phosphatase; Animals; Antioxidants; Beverages; Camellia sinensis; Chemical and Drug Induced Liver Injury; Fermentation; Glucaric Acid; Gluconacetobacter; Lactones; Liver; Male; Malondialdehyde; Mice; Mice, Inbred ICR; Plant Extracts; Tea; Triglycerides; Yeasts | 2014 |
Overestimation of flavonoid aglycones as a result of the ex vivo deconjugation of glucuronides by the tissue β-glucuronidase.
Topics: Animals; Chromatography, High Pressure Liquid; Dietary Supplements; Dose-Response Relationship, Drug; Flavanones; Flavonoids; Glucaric Acid; Glucuronidase; Glucuronides; Glycoproteins; Humans; Lactones; Liver; Liver Neoplasms; Methylation; Mice; Pancreas; Quercetin; Xenograft Model Antitumor Assays | 2014 |
Evaluation of the thiazole Schiff bases as β-glucuronidase inhibitors and their in silico studies.
Topics: Computer Simulation; Enzyme Inhibitors; Glucaric Acid; Glucuronidase; Inhibitory Concentration 50; Lactones; Models, Molecular; Molecular Conformation; Schiff Bases; Thiazoles | 2014 |
β-glucuronidase inhibitory studies on coumarin derivatives.
Topics: Bacterial Proteins; Coumarins; Dose-Response Relationship, Drug; Enzyme Assays; Enzyme Inhibitors; Escherichia coli; Glucaric Acid; Glucuronidase; Kinetics; Lactones; Molecular Structure; Structure-Activity Relationship | 2014 |
Alteration of gut bacteria and metabolomes after glucaro-1,4-lactone treatment contributes to the prevention of hypercholesterolemia.
Topics: Animals; Bifidobacterium; Cholesterol, Dietary; Creatinine; Diet, High-Fat; Female; Gastrointestinal Tract; Glucaric Acid; Hypercholesterolemia; Lactobacillus; Liver; Metabolome; Methylamines; Probiotics; Rats; Rats, Sprague-Dawley; Triglycerides | 2014 |
Application of metabonomic strategy to discover an unreported active ingredient in LiuWeiDiHuang pills suppressing beta-glucuronidase.
Topics: Animals; Biomarkers; Chromatography, High Pressure Liquid; Discriminant Analysis; Drugs, Chinese Herbal; Enzyme Inhibitors; Glucaric Acid; Glucuronidase; Least-Squares Analysis; Magnetic Resonance Spectroscopy; Male; Metabolomics; Rats, Sprague-Dawley; Urinalysis | 2015 |
Regulation of the voltage gated K channel Kv1.3 by recombinant human klotho protein.
Topics: Animals; Cell Line, Tumor; Glucaric Acid; Glucuronidase; Humans; Klotho Proteins; Kv1.3 Potassium Channel; Lactones; Oocytes; Patch-Clamp Techniques; Recombinant Proteins; Xenopus | 2014 |
Triple Recycling Processes Impact Systemic and Local Bioavailability of Orally Administered Flavonoids.
Topics: Administration, Oral; Animals; Bile; Biological Availability; Flavones; Flavonoids; Glucaric Acid; Gluconates; Glucuronidase; Glucuronides; Glycosides; Half-Life; Intestinal Mucosa; Lactase-Phlorizin Hydrolase; Lactones; Male; Rats; Rats, Sprague-Dawley | 2015 |
Kombucha tea fermentation: Microbial and biochemical dynamics.
Topics: Bacteria; Biodiversity; Biofilms; Candida; Fermentation; Glucaric Acid; Kombucha Tea; Lactones; Microbiota; Saccharomycetales | 2016 |
Determination of D-glucaric acid and/or D-glucaro-1,4-lacton in different apple varieties through hydrophilic interaction chromatography.
Topics: Animals; Biotransformation; Calibration; Chromatography, High Pressure Liquid; Fruit; Gastric Mucosa; Glucaric Acid; Hydrophobic and Hydrophilic Interactions; Limit of Detection; Male; Malus; Plant Extracts; Rats, Sprague-Dawley; Species Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2016 |
Involvement of bilitranslocase and beta-glucuronidase in the vascular protection by hydroxytyrosol and its glucuronide metabolites in oxidative stress conditions.
Topics: Animals; Antioxidants; Aorta, Thoracic; Biological Transport, Active; Ceruloplasmin; Dietary Supplements; Endothelium, Vascular; Enzyme Inhibitors; Glucaric Acid; Glucuronidase; Glucuronides; In Vitro Techniques; Male; Membrane Transport Modulators; Oxidants; Oxidative Stress; Phenylethyl Alcohol; Phenylmethylsulfonyl Fluoride; Rats, Wistar; tert-Butylhydroperoxide; Vascular Diseases; Vasodilation | 2018 |
Three structurally and functionally distinct β-glucuronidases from the human gut microbe
Topics: Amino Acid Sequence; Bacteroides; Catalytic Domain; Enzyme Inhibitors; Gastrointestinal Microbiome; Glucaric Acid; Glucuronidase; Humans; Isoenzymes; Protein Conformation | 2018 |
Metabonomics of d-glucaro-1,4-lactone in preventing diethylnitrosamine-induced liver cancer in rats.
Topics: Alkylating Agents; Animals; Diethylnitrosamine; Glucaric Acid; Liver Neoplasms, Experimental; Metabolomics; Rats; Rats, Sprague-Dawley | 2018 |