glucaric acid has been researched along with phenobarbital in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 26 (89.66) | 18.7374 |
| 1990's | 2 (6.90) | 18.2507 |
| 2000's | 1 (3.45) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hildebrandt, AG; Kewitz, H; Roots, I; Saalfrank, K; Speck, M | 1 |
| Hosková, A; Pojerová, A; Talafant, E | 2 |
| Kirchhof, B; Ohnhaus, EE; Peheim, E | 1 |
| Ohnhaus, EE; Park, BK | 1 |
| Nambara, K | 1 |
| Foglietti, MJ; Micheletti, C; Percheron, F | 1 |
| Carrella, M; D'Arienzo, A; De Ritis, F; Manzillo, G | 1 |
| Latham, AN | 1 |
| Eriksson, K; Hänninen, O; Marselos, M | 1 |
| Laitinen, M; Marselos, M | 1 |
| Marselos, M | 1 |
| Gladtke, E; Heimann, G; Roth, B | 1 |
| Barak, AJ; Burnett, DA; Sorrell, MF; Tuma, DJ | 1 |
| Franklin, C; Latham, AN; Maclay, W; Turner, P | 1 |
| Latham, AN; Sweeney, GD | 1 |
| Dutton, G; Hänninen, O; Marselos, M | 1 |
| Lecamwasam, DS | 1 |
| Franklin, C; Lecamwasam, DS; Turner, P | 1 |
| Gilbert, PJ; Hoyle, VR; Nicholson, JK; Troke, JA; Vose, CW | 1 |
| Feely, MP; Hay, A; Mehta, A; Park, BK; Price, DE | 1 |
| Pelkonen, RO; Puukka, M; Sotaniemi, EA | 1 |
| Hirayama, C; Kawasaki, H; Kimura, N; Murawaki, Y | 1 |
| Hedges, A; Makki, KA; Perucca, E; Richens, A; Ruprah, M; Wilson, JF | 1 |
| Kinoshita, H; Kuroiwa, Y; Tanaka, E; Yoshida, T | 1 |
| Levy, RH; Patel, IH; Wedlund, P | 1 |
| Hildebrandt, AG; Kampf, D; Roots, I | 1 |
| Banfield, CR; Colucci, RD; Glue, P; Guillaume, M; Lin, CC; Meehan, JW; Mojavarian, P; Nezamis, J; Radwanski, E; Reidenberg, P | 1 |
| Fernández, MP; Hermida, J; Tutor, JC | 1 |
2 trial(s) available for glucaric acid and phenobarbital
| Article | Year |
|---|---|
Evaluation of in vivo parameters of drug metabolizing enzyme activity in man after administration of clemastine, phenobarbital or placebo.
Topics: 17-Hydroxycorticosteroids; Adult; Aminopyrine; Clinical Trials as Topic; Drug Evaluation; Enzyme Induction; gamma-Glutamyltransferase; Glucaric Acid; Half-Life; Humans; Hydrocortisone; Kinetics; Male; Phenobarbital; Placebos | 1975 |
Effects of felbamate on the pharmacokinetics of phenobarbital.
Topics: Adult; Anticonvulsants; Double-Blind Method; Drug Administration Schedule; Drug Interactions; Felbamate; Glucaric Acid; Humans; Male; Phenobarbital; Phenylcarbamates; Placebos; Propylene Glycols | 1995 |
27 other study(ies) available for glucaric acid and phenobarbital
| Article | Year |
|---|---|
Serum gamma-glutamyl transpeptidase activity and urinary D-glucaric acid excretion in newborns in the first week of life. Effects of phenobarbital and nicethamide combination.
Topics: Bilirubin; gamma-Glutamyltransferase; Glucaric Acid; Humans; Infant, Newborn; Male; Nikethamide; Phenobarbital; Stimulation, Chemical; Sugar Acids; Time Factors | 1976 |
Effect of enzyme induction on plasma lipids using antipyrine, phenobarbital, and rifampicin.
Topics: 17-Hydroxycorticosteroids; Adult; Antipyrine; Cholesterol; Enzyme Induction; Female; gamma-Glutamyltransferase; Glucaric Acid; Humans; Hydrocortisone; Hydroxylation; Lipids; Lipoproteins; Male; Microsomes, Liver; Phenobarbital; Phospholipids; Rifampin; Triglycerides | 1979 |
Measurement of urinary 6-beta-hydroxycortisol excretion as an in vivo parameter in the clinical assessment of the microsomal enzyme-inducing capacity of antipyrine, phenobarbitone and rifampicin.
Topics: 17-Hydroxycorticosteroids; Adult; Antipyrine; Enzyme Induction; Female; gamma-Glutamyltransferase; Glucaric Acid; Humans; Hydrocortisone; Hydroxylation; Kinetics; Male; Microsomes, Liver; Phenobarbital; Rifampin | 1979 |
[Clinical and experimental studies on the enzymes of liver, small intestinal mucosa and pancreas after chronic ethanol ingestion and anti-epileptic drugs (author's transl)].
Topics: Alcoholism; Animals; Glucaric Acid; Humans; Intestinal Mucosa; Intestine, Small; Liver; Male; NADPH-Ferrihemoprotein Reductase; Pancreas; Phenobarbital; Phenytoin; Rats; Succinate Cytochrome c Oxidoreductase | 1979 |
[Enzymatic induction during isoniazid therapy (author's transl)].
Topics: Acetylation; Enzyme Induction; Glucaric Acid; Humans; Isoniazid; Oxidoreductases; Phenobarbital; Phenotype | 1979 |
An evaluation of urinary D-glucaric acid excretion during acute hepatitis in man.
Topics: Acute Disease; Adult; Bilirubin; Child; Glucaric Acid; Glucuronates; Hepatitis, Viral, Human; Humans; Male; Phenobarbital; Sugar Acids; Transaminases | 1978 |
Effect of data transformation on t-test sensitivity.
Topics: Adult; Animals; Anticonvulsants; Epilepsy; Glucaric Acid; Guinea Pigs; Humans; Mathematics; Phenobarbital; Statistics as Topic; Time Factors | 1978 |
Aldehyde dehydrogenase inducibility and ethanol preference in rats.
Topics: Acetaldehyde; Alcohol Drinking; Alcohol Oxidoreductases; Animals; Ascorbic Acid; Cytosol; Drinking Behavior; Ethanol; Female; Glucaric Acid; Glucuronates; Glucuronosyltransferase; Lactones; Liver; Male; Phenobarbital; Rats; Rats, Inbred Strains; Stimulation, Chemical | 1975 |
Starvation and phenobarbital treatment effects on drug hydroxylation and glucuronidation in the rat liver and small intestinal mucosa.
Topics: Animals; Ascorbic Acid; Cholesterol; Cytochrome P-450 Enzyme System; Glucaric Acid; Glucuronates; Glucuronidase; Glucuronosyltransferase; Hydroxylation; Intestinal Mucosa; Liver; Male; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Nitroanisole O-Demethylase; Phenobarbital; Phospholipids; Proteins; Rats; Rats, Inbred Strains; Starvation; Uridine Diphosphate Glucose Dehydrogenase | 1975 |
Genetic variation of drug-metabolizing enzymes in the wistar rat.
Topics: Alcohol Oxidoreductases; Aldehyde Oxidoreductases; Animals; Cytochrome Reductases; Female; Genetic Variation; Glucaric Acid; Liver; Male; NADPH-Ferrihemoprotein Reductase; Phenobarbital; Rats; Rats, Inbred WF | 1976 |
Negative feedback control of neonatal serum creatine and increased urinary creatinine excretion after enzyme-inducing drugs.
Topics: Bilirubin; Creatine; Creatinine; Feedback; Glucaric Acid; Humans; Infant, Newborn; Male; Nikethamide; Phenobarbital | 1977 |
[Excretion of D-glucaric-acid in newborns with non-hemolytic hyperbilirubinemia after phenobarbital treatment (author's transl)].
Topics: Bilirubin; Female; Glucaric Acid; Humans; Hyperbilirubinemia; Infant, Newborn; Male; Phenobarbital; Sugar Acids; Time Factors | 1977 |
Paradoxical urinary excretion of D-glucaric acid in acute viral hepatitis.
Topics: Acute Disease; Antipyrine; Female; Glucaric Acid; Hepatitis A; Humans; Male; Phenobarbital; Sugar Acids | 1976 |
Phenobarbitone-induced urinary excretions of D-glucaric acid and 6beta-hydroxycortisol in man.
Topics: Adult; Glucaric Acid; Humans; Hydrocortisone; Male; Middle Aged; Phenobarbital; Placebos; Sugar Acids; Time Factors | 1976 |
Binding of anticonvulsant drugs to cytochrome P-450: correlation with evidence of induction of hepatic microsomal enzymes.
Topics: Animals; Anticonvulsants; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Induction; Glucaric Acid; Hexobarbital; In Vitro Techniques; Kinetics; Male; Mephenytoin; Microsomes, Liver; Phenobarbital; Phenylbutyrates; Phenytoin; Rats; Receptors, Drug; Urea | 1976 |
Evidence that D-glucaro-1,4-lactone shortens the pharmacological action of drugs being disposed via the bile as glucuronides.
Topics: Animals; Bile; Depression, Chemical; Drug Interactions; Glucaric Acid; Glucuronates; Glucuronidase; In Vitro Techniques; Intestines; Lactones; Male; Mice; Motor Activity; Pharmaceutical Preparations; Phenobarbital; Progesterone; Rats; Rats, Inbred Strains; Sugar Acids; Zoxazolamine | 1975 |
Hepatic enzyme induction and its relationship to urinary D-glucaric acid excretion in man.
Topics: Adult; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Glucaric Acid; Humans; Liver; Male; Microsomes, Liver; Phenobarbital; Sugar Acids | 1975 |
Effect of phenobarbitone on hepatic drug-metabolizing enzymes and urinary D-glucaric acid excretion in man.
Topics: Adolescent; Adult; Aged; Biotransformation; Enzyme Induction; Female; Glucaric Acid; Hodgkin Disease; Humans; Liver; Male; Middle Aged; Mixed Function Oxygenases; Oxidoreductases; Phenobarbital; Sugar Acids | 1975 |
Studies on the biochemical effects of the aldose reductase inhibitor 2,7-difluorospirofluorene-9,5'-imidazolidine-2',4'-dione (Al 1576, HOE 843). Detection of D-glucaric and D-glucuronic acid excretion by high resolution 1H and 13C NMR spectroscopy.
Topics: Aldehyde Reductase; Animals; Carbohydrate Dehydrogenases; Enzyme Induction; Female; Fluorenes; Glucaric Acid; Glucuronates; Glucuronic Acid; Hydantoins; Liver; Magnetic Resonance Spectroscopy; Phenobarbital; Rats; Rats, Inbred Strains | 1992 |
The effect of low-dose phenobarbitone on three indices of hepatic microsomal enzyme induction.
Topics: Adult; Antipyrine; Dose-Response Relationship, Drug; Enzyme Induction; Female; Glucaric Acid; Humans; Hydrocortisone; Male; Metabolic Clearance Rate; Microsomes, Liver; Phenobarbital | 1986 |
Measurement of hepatic drug-metabolizing enxyme activity in man. Comparison of three different assays.
Topics: Adult; Aged; Antipyrine; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Glucaric Acid; Hepatitis; Histamine H1 Antagonists; Humans; Liver; Liver Cirrhosis; Male; Medroxyprogesterone; Middle Aged; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Prednisolone; Rifampin | 1980 |
Effects of phenobarbital on unconjugated bilirubin clearance, gamma-glutamyltranspeptidase and urinary d-glucaric acid in patients with Gilbert's syndrome.
Topics: Adult; Bilirubin; Female; gamma-Glutamyltransferase; Gilbert Disease; Glucaric Acid; Humans; Hyperbilirubinemia, Hereditary; Kinetics; Male; Phenobarbital; Sugar Acids | 1982 |
A comparative study of the relative enzyme inducing properties of anticonvulsant drugs in epileptic patients.
Topics: Anticonvulsants; Antipyrine; Carbamazepine; Enzyme Induction; Epilepsy; Female; Glucaric Acid; Half-Life; Humans; Immunoenzyme Techniques; Male; Microsomes, Liver; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1984 |
Studies on the trimethadione metabolism as a tool for the assessment of drug-metabolizing capacity using plasma and urine of rats pretreated with phenobarbital and 3-methylcholanthrene.
Topics: Animals; Biotransformation; Creatinine; Glucaric Acid; Hydrogen-Ion Concentration; Liver; Male; Methylcholanthrene; Oxazoles; Pharmaceutical Preparations; Phenobarbital; Rats; Rats, Inbred Strains; Time Factors; Trimethadione | 1982 |
Induction effect of phenobarbital on the carbamazepine to carbamazepine-10, 11-epoxide pathway in rhesus monkeys.
Topics: Animals; Carbamazepine; Drug Interactions; Enzyme Induction; Glucaric Acid; Kinetics; Macaca mulatta; Models, Biological; Phenobarbital; Time Factors | 1981 |
Urinary excretion of D-glucaric acid, an indicator of drug metabolizing enzyme activity, in patients with impaired renal function.
Topics: Adult; Aged; Female; Glomerular Filtration Rate; Glucaric Acid; Humans; Kidney Diseases; Male; Middle Aged; Phenobarbital; Sugar Acids | 1980 |
Relationship between changes in drug score, D-glucaric acid excretion, and gamma-glutamyltransferase and beta-glucuronidase serum activities during anticonvulsant treatment.
Topics: Adult; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Enzyme Induction; Epilepsy; Female; Follow-Up Studies; gamma-Glutamyltransferase; Glucaric Acid; Glucuronidase; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Sex Factors | 2002 |