Page last updated: 2024-09-04

glucagon and u-50488

glucagon has been researched along with u-50488 in 2 studies

Compound Research Comparison

Studies (glucagon)	Trials (glucagon)	Recent Studies (post-2010) (glucagon)	Studies (u-50488)	Trials (u-50488)	Recent Studies (post-2010) (u-50488)
26,039	1,498	3,054	1,664	3	209

Protein Interaction Comparison

Protein	Taxonomy	u-50488 (IC50)
Delta-type opioid receptor	Rattus norvegicus (Norway rat)	2.15
Kappa-type opioid receptor	Mus musculus (house mouse)	0.0027
Mu-type opioid receptor	Rattus norvegicus (Norway rat)	2.15
Kappa-type opioid receptor	Rattus norvegicus (Norway rat)	0.7171
Kappa-type opioid receptor	Cavia porcellus (domestic guinea pig)	0.0958
Kappa-type opioid receptor	Homo sapiens (human)	0.0537

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (50.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bailey, CJ; Green, IC; Khawaja, XZ; Thorpe, JR	1
Buxbaum, JD; Cho, J; Jacobson, DA; Landa, LR; Philipson, LH; Roe, MW; Tamarina, NA	1

Other Studies

2 other study(ies) available for glucagon and u-50488

Article	Year
Increased sensitivity to insulin-releasing and glucoregulatory effects of dynorphin A1-13 and U 50488h in ob/ob versus lean mice. Diabetes, 1990, Volume: 39, Issue:10 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Antihypertensive Agents; Blood Glucose; Dynorphins; Glucagon; Glucose Tolerance Test; Immunoenzyme Techniques; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Mice; Mice, Obese; Peptide Fragments; Pyrrolidines; Reference Values	1990
Downstream regulatory element antagonistic modulator regulates islet prodynorphin expression. American journal of physiology. Endocrinology and metabolism, 2006, Volume: 291, Issue:3 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Calcium; Cell Line; Cell Nucleus; DNA; Dynorphins; Electrophoretic Mobility Shift Assay; Enkephalins; Gene Expression Regulation; Glucagon; Glucagon-Secreting Cells; Glucose; Humans; Insulin-Secreting Cells; Islets of Langerhans; Kv Channel-Interacting Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Naltrexone; Protein Binding; Protein Precursors; Receptors, Opioid, kappa; Repressor Proteins	2006

Article

Year

Increased sensitivity to insulin-releasing and glucoregulatory effects of dynorphin A1-13 and U 50488h in ob/ob versus lean mice.

Diabetes, 1990, Volume: 39, Issue:10

Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Antihypertensive Agents; Blood Glucose; Dynorphins; Glucagon; Glucose Tolerance Test; Immunoenzyme Techniques; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Mice; Mice, Obese; Peptide Fragments; Pyrrolidines; Reference Values

1990

Downstream regulatory element antagonistic modulator regulates islet prodynorphin expression.

American journal of physiology. Endocrinology and metabolism, 2006, Volume: 291, Issue:3

Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Calcium; Cell Line; Cell Nucleus; DNA; Dynorphins; Electrophoretic Mobility Shift Assay; Enkephalins; Gene Expression Regulation; Glucagon; Glucagon-Secreting Cells; Glucose; Humans; Insulin-Secreting Cells; Islets of Langerhans; Kv Channel-Interacting Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Naltrexone; Protein Binding; Protein Precursors; Receptors, Opioid, kappa; Repressor Proteins

2006