Page last updated: 2024-09-04

glucagon and tak-875

glucagon has been researched along with tak-875 in 2 studies

Compound Research Comparison

Studies (glucagon)	Trials (glucagon)	Recent Studies (post-2010) (glucagon)	Studies (tak-875)	Trials (tak-875)	Recent Studies (post-2010) (tak-875)
26,039	1,498	3,054	121	15	116

Protein Interaction Comparison

Protein	Taxonomy	tak-875 (IC50)
Sodium/bile acid cotransporter	Homo sapiens (human)	2
Canalicular multispecific organic anion transporter 1	Homo sapiens (human)	2.41
Solute carrier organic anion transporter family member 1B1	Homo sapiens (human)	2.28

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Hazama, M; Johnson, PR; Rorsman, P; Takeuchi, K; Tsujihata, Y; Yashiro, H	1
Ito, R; Matsuda-Nagasumi, K; Mori, I; Negoro, N; Takeuchi, K; Tsujihata, Y	1

Other Studies

2 other study(ies) available for glucagon and tak-875

Article	Year
The effects of TAK-875, a selective G protein-coupled receptor 40/free fatty acid 1 agonist, on insulin and glucagon secretion in isolated rat and human islets. The Journal of pharmacology and experimental therapeutics, 2012, Volume: 340, Issue:2 Topics: Animals; ATP-Binding Cassette Transporters; Benzofurans; Calcium Signaling; Drug Synergism; Gene Expression; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Secreting Cells; Glucose; Humans; In Vitro Techniques; Insulin; Insulin Secretion; Insulin-Secreting Cells; Islets of Langerhans; Potassium Channels, Inwardly Rectifying; Rats; Rats, Sprague-Dawley; Receptors, Drug; Receptors, G-Protein-Coupled; Receptors, Glucagon; Sulfones; Sulfonylurea Receptors	2012
TAK-875, a GPR40/FFAR1 agonist, in combination with metformin prevents progression of diabetes and β-cell dysfunction in Zucker diabetic fatty rats. British journal of pharmacology, 2013, Volume: 170, Issue:3 Topics: Animals; Benzofurans; Biomarkers; Blood Glucose; Diabetes Mellitus, Type 2; Disease Models, Animal; Disease Progression; Drug Therapy, Combination; Glucagon; Glycated Hemoglobin; Homeodomain Proteins; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin-Secreting Cells; Male; Metformin; Proliferating Cell Nuclear Antigen; Rats; Rats, Zucker; Receptors, G-Protein-Coupled; Sulfones; Time Factors; Trans-Activators	2013

Article

Year

The effects of TAK-875, a selective G protein-coupled receptor 40/free fatty acid 1 agonist, on insulin and glucagon secretion in isolated rat and human islets.

The Journal of pharmacology and experimental therapeutics, 2012, Volume: 340, Issue:2

Topics: Animals; ATP-Binding Cassette Transporters; Benzofurans; Calcium Signaling; Drug Synergism; Gene Expression; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Secreting Cells; Glucose; Humans; In Vitro Techniques; Insulin; Insulin Secretion; Insulin-Secreting Cells; Islets of Langerhans; Potassium Channels, Inwardly Rectifying; Rats; Rats, Sprague-Dawley; Receptors, Drug; Receptors, G-Protein-Coupled; Receptors, Glucagon; Sulfones; Sulfonylurea Receptors

2012

TAK-875, a GPR40/FFAR1 agonist, in combination with metformin prevents progression of diabetes and β-cell dysfunction in Zucker diabetic fatty rats.

British journal of pharmacology, 2013, Volume: 170, Issue:3

Topics: Animals; Benzofurans; Biomarkers; Blood Glucose; Diabetes Mellitus, Type 2; Disease Models, Animal; Disease Progression; Drug Therapy, Combination; Glucagon; Glycated Hemoglobin; Homeodomain Proteins; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin-Secreting Cells; Male; Metformin; Proliferating Cell Nuclear Antigen; Rats; Rats, Zucker; Receptors, G-Protein-Coupled; Sulfones; Time Factors; Trans-Activators

2013