Compounds > glucagon
Page last updated: 2024-09-04

glucagon and tacrolimus

glucagon has been researched along with tacrolimus in 6 studies

Compound Research Comparison

Studies
(glucagon)		Trials
(glucagon)		Recent Studies (post-2010)
(glucagon)		Studies
(tacrolimus)		Trials
(tacrolimus)		Recent Studies (post-2010) (tacrolimus)
26,0391,4983,05417,7572,3196,661

Protein Interaction Comparison

ProteinTaxonomyglucagon (IC50)tacrolimus (IC50)
Bile salt export pumpHomo sapiens (human)7.18
Cytochrome P450 3A4Homo sapiens (human)0.58
Cytochrome P450 3A5Homo sapiens (human)0.385
Serine/threonine-protein kinase mTORHomo sapiens (human)0.0021
Peptidyl-prolyl cis-trans isomerase FKBP1AHomo sapiens (human)0.2547
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoformHomo sapiens (human)0.0148
Splicing factor 3B subunit 3Homo sapiens (human)0.0123
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)3.3
Solute carrier organic anion transporter family member 1B1Homo sapiens (human)3.7

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (50.00)18.2507
2000's1 (16.67)29.6817
2010's1 (16.67)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Alejandro, R; Mintz, DH; Ricordi, C; Strasser, S; Todo, S1
Bechstein, WO; Dette, K; Gräf, KJ; Leder, K; Mueller, AR; Neuhaus, P; Schleicher, J; Schulz, E; Steinmüller, TM1
Blume, R; Knepel, W; Lux, G; Oetjen, E; Schwaninger, M1
Bhatt, HS; Easom, RA; Lawrence, MC1
Mueller, R; Naji, A; Rickels, MR; Teff, KL1
Han, DJ; Jung, CH; Jung, JH; Kim, DH; Kim, YH; Ko, Y; Kwon, H; Lim, SJ; Mun, S; Shin, S1

Trials

1 trial(s) available for glucagon and tacrolimus

ArticleYear
The effect of FK506 versus cyclosporine on glucose and lipid metabolism--a randomized trial.
    Transplantation, 1994, Sep-27, Volume: 58, Issue:6

    Topics: Adolescent; Adult; Aged; Blood Glucose; Cholesterol; Cyclosporine; Female; Glucagon; Glucose Tolerance Test; Humans; Insulin; Lipids; Liver Transplantation; Male; Middle Aged; Prospective Studies; Tacrolimus; Triglycerides

1994

Other Studies

5 other study(ies) available for glucagon and tacrolimus

ArticleYear
The effect of FK 506 on canine pancreatic islet cell function in beagle dogs.
    Transplantation proceedings, 1991, Volume: 23, Issue:1 Pt 1

    Topics: Animals; Anti-Bacterial Agents; Blood Glucose; Dogs; Glucagon; Glucose Tolerance Test; Immunosuppressive Agents; Insulin; Insulin Secretion; Islets of Langerhans; Tacrolimus

1991
Inhibition of cAMP-responsive element-mediated gene transcription by cyclosporin A and FK506 after membrane depolarization.
    The Journal of biological chemistry, 1993, Nov-05, Volume: 268, Issue:31

    Topics: Activating Transcription Factor 2; Animals; Calcineurin; Calcium; Calmodulin-Binding Proteins; Cell Line; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclosporine; Gene Expression; Glucagon; Islets of Langerhans; Membrane Potentials; Phosphoprotein Phosphatases; Polyenes; Rats; Regulatory Sequences, Nucleic Acid; Sirolimus; Tacrolimus; Transcription Factors

1993
NFAT regulates insulin gene promoter activity in response to synergistic pathways induced by glucose and glucagon-like peptide-1.
    Diabetes, 2002, Volume: 51, Issue:3

    Topics: Animals; Calcineurin; Calcineurin Inhibitors; Calcium; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DNA-Binding Proteins; Drug Synergism; Enzyme Inhibitors; Gene Expression Regulation; Glucagon; Glucagon-Like Peptide 1; Glucose; Insulin; Islets of Langerhans; Isoquinolines; NFATC Transcription Factors; Nuclear Proteins; Peptide Fragments; Promoter Regions, Genetic; Protein Precursors; Rats; Sulfonamides; Tacrolimus; Transcription Factors; Transcription, Genetic

2002
{beta}-Cell secretory capacity and demand in recipients of islet, pancreas, and kidney transplants.
    The Journal of clinical endocrinology and metabolism, 2010, Volume: 95, Issue:3

    Topics: Adult; Analysis of Variance; Arginine; Blood Glucose; Female; Glucagon; Humans; Immunosuppressive Agents; Insulin; Insulin-Secreting Cells; Islets of Langerhans Transplantation; Kidney Function Tests; Kidney Transplantation; Male; Middle Aged; Pancreas Transplantation; Tacrolimus

2010
Lack of Improvement in Insulin Sensitivity After Pancreas Transplantation in Recipients With a High Level of Calcineurin Inhibitors.
    Pancreas, 2021, 04-01, Volume: 50, Issue:4

    Topics: Adult; Blood Glucose; Calcineurin Inhibitors; Cyclosporine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Glucagon; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Insulin-Secreting Cells; Kaplan-Meier Estimate; Male; Middle Aged; Pancreas Transplantation; Tacrolimus

2021