Page last updated: 2024-09-04

glucagon and staurosporine

glucagon has been researched along with staurosporine in 11 studies

Compound Research Comparison

Studies
(glucagon)
Trials
(glucagon)
Recent Studies (post-2010)
(glucagon)
Studies
(staurosporine)
Trials
(staurosporine)
Recent Studies (post-2010) (staurosporine)
26,0391,4983,0546,27258976

Protein Interaction Comparison

ProteinTaxonomyglucagon (IC50)staurosporine (IC50)
Chain A, Ribosomal protein S6 kinase alpha-1Homo sapiens (human)0.0003
Chain X, Tyrosine-protein kinase LynHomo sapiens (human)0.0013

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's10 (90.91)18.2507
2000's1 (9.09)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jansen, PL; Ottenhoff, R; Oude Elferink, RP; Roelofsen, H1
Gustafsson, JA; Legraverend, C; Mode, A; Tollet, P1
Ahrén, B; Fridolf, T1
Kachra, Z; Posner, BI; Yang, CR1
Houslay, MD; Savage, A; Zeng, L1
Kolehmainen, E1
Bode, HP; Fehmann, HC; Göke, B; Williams, JA; Yule, DI1
Meijer, DK; Merema, M; Nijholt, A; Smit, H; Steen, H1
Gespach, CP; Hanson, PJ; McKenna, P; Williams, JM1
Bode, HP; Dabew, R; Göke, B; Moormann, B1
Brubaker, PL; Li, L; Rhodes, C; Wang, Q; Wong, V; Xu, E1

Other Studies

11 other study(ies) available for glucagon and staurosporine

ArticleYear
Hepatocanalicular organic-anion transport is regulated by protein kinase C.
    The Biochemical journal, 1991, Sep-15, Volume: 278 ( Pt 3)

    Topics: 1-Methyl-3-isobutylxanthine; Alkaloids; Animals; Anion Transport Proteins; Anions; Bile Canaliculi; Biological Transport; Bucladesine; Carrier Proteins; Colforsin; Cyclic AMP; Glucagon; Glutathione; Male; Protein Kinase C; Rats; Rats, Inbred Strains; Second Messenger Systems; Staurosporine; Tetradecanoylphorbol Acetate; Vasopressins

1991
A role for protein kinases in the growth hormone regulation of cytochrome P4502C12 and insulin-like growth factor-I messenger RNA expression in primary adult rat hepatocytes.
    Molecular endocrinology (Baltimore, Md.), 1991, Volume: 5, Issue:9

    Topics: Alkaloids; Animals; Cells, Cultured; Cytochrome P-450 Enzyme System; Diglycerides; Down-Regulation; Enzyme Activation; Gene Expression Regulation; Glucagon; Growth Hormone; Insulin-Like Growth Factor I; Liver; Male; Protein Kinase C; Rats; Rats, Inbred Strains; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Transcription, Genetic

1991
GLP-1(7-36) amide stimulates insulin secretion in rat islets: studies on the mode of action.
    Diabetes research (Edinburgh, Scotland), 1991, Volume: 16, Issue:4

    Topics: Alkaloids; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Peptide Fragments; Peptides; Protein Kinase C; Rats; Rats, Inbred Strains; Staurosporine

1991
The augmentation of insulin-like growth factor-I messenger ribonucleic acid in cultured rat hepatocytes: activation of protein kinase-A and -C is necessary, but not sufficient.
    Endocrinology, 1994, Volume: 134, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Alkaloids; Animals; Blotting, Northern; Bucladesine; Cattle; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Drug Synergism; Enzyme Activation; Glucagon; Growth Hormone; Insulin-Like Growth Factor I; Isoquinolines; Kinetics; Liver; Male; Piperazines; Protein Kinase C; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate

1994
A role for protein kinase C-mediated phosphorylation in eliciting glucagon desensitization in rat hepatocytes.
    The Biochemical journal, 1995, Apr-01, Volume: 307 ( Pt 1)

    Topics: Adenylyl Cyclases; Alkaline Phosphatase; Alkaloids; Animals; Arginine Vasopressin; Benzophenanthridines; Cell Adhesion; Cells, Cultured; Collagen; Cyclic AMP; Drug Tolerance; Ethers, Cyclic; Glucagon; Liver; Male; Naphthalenes; Okadaic Acid; Phenanthridines; Phosphorylation; Polycyclic Compounds; Protein Kinase C; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Signal Transduction; Staurosporine

1995
Mechanism of the myelin basic protein-induced insulin and glucagon release from isolated rat pancreatic islets.
    Neurochemistry international, 1995, Volume: 26, Issue:4

    Topics: Alkaloids; Animals; Calcium; Ethanol; Female; Glucagon; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Maleates; Methylation; Myelin Basic Protein; Protein Kinase C; Rats; Rats, Sprague-Dawley; Staurosporine; Stimulation, Chemical; Temperature

1995
Spontaneous calcium oscillations in clonal endocrine pancreatic glucagon-secreting cells.
    Biochemical and biophysical research communications, 1994, Nov-30, Volume: 205, Issue:1

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Alkaloids; Calcium; Cell Line; Cyclic GMP; Estrenes; Glucagon; Pancreas; Protein Kinase C; Pyrrolidinones; Staurosporine; Terpenes; Thapsigargin; Type C Phospholipases

1994
Modulators of the protein kinase C system influence biliary excretion of cationic drugs.
    Hepatology (Baltimore, Md.), 1993, Volume: 18, Issue:5

    Topics: Alkaloids; Animals; Bile; Biological Transport, Active; Carrier Proteins; Cations; Cell Membrane; Cells, Cultured; Colforsin; Cyclic AMP; Glucagon; In Vitro Techniques; Liver; Male; Perfusion; Protein Kinase C; Quaternary Ammonium Compounds; Rats; Rats, Wistar; Second Messenger Systems; Staurosporine; Tetradecanoylphorbol Acetate; Vasopressins

1993
Protein kinase C inhibits cyclic adenosine monophosphate generation by histamine and truncated glucagon like peptide 1 in the human gastric cancer cell line HGT-1.
    Gut, 1993, Volume: 34, Issue:7

    Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Alkaloids; Cyclic AMP; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Histamine; Humans; Peptide Fragments; Pertussis Toxin; Protein Kinase C; Protein Precursors; Receptors, Gastrointestinal Hormone; Receptors, Histamine H2; Staurosporine; Stimulation, Chemical; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Virulence Factors, Bordetella

1993
Glucagon-like peptide 1 elevates cytosolic calcium in pancreatic beta-cells independently of protein kinase A.
    Endocrinology, 1999, Volume: 140, Issue:9

    Topics: Animals; Calcium; Cell Line; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytosol; Enzyme Inhibitors; Glucagon; Glucagon-Like Peptide 1; Islets of Langerhans; Male; Mice; Mice, Inbred DBA; Osmolar Concentration; Peptide Fragments; Protein Kinase Inhibitors; Protein Precursors; Staurosporine

1999
Glucagon-like peptide-1 regulates proliferation and apoptosis via activation of protein kinase B in pancreatic INS-1 beta cells.
    Diabetologia, 2004, Volume: 47, Issue:3

    Topics: Animals; Apoptosis; Cell Division; Cell Line; Glucagon; Glucagon-Like Peptide 1; Insulin; Insulin Secretion; Islets of Langerhans; Peptide Fragments; Protein Precursors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Reverse Transcriptase Polymerase Chain Reaction; Staurosporine

2004