glucagon has been researched along with oxyntomodulin in 802 studies
| Studies (glucagon) | Trials (glucagon) | Recent Studies (post-2010) (glucagon) | Studies (oxyntomodulin) | Trials (oxyntomodulin) | Recent Studies (post-2010) (oxyntomodulin) |
|---|---|---|---|---|---|
| 26,039 | 1,498 | 3,054 | 2,150 | 268 | 916 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 201 (25.06) | 18.7374 |
| 1990's | 365 (45.51) | 18.2507 |
| 2000's | 182 (22.69) | 29.6817 |
| 2010's | 37 (4.61) | 24.3611 |
| 2020's | 17 (2.12) | 2.80 |
| Authors | Studies |
|---|---|
| Alumets, J; Håkanson, R; O'Dorisio, T; Sjölund, K; Sundler, F | 1 |
| Bech, A; Christiansen, J; Fahrenkrug, J; Holst, JJ; Lauritsen, K; Moody, AJ; Schaffalitzky de Muckadell, O | 1 |
| Bloom, SR; Bryant, MG | 1 |
| Jones, RS; Meyers, WC | 1 |
| Rehfeld, JF | 1 |
| Diez-Jarilla, JL; Gonzalez-Macias, J; Laso-Guzman, FJ; Sanchez-Rodriguez, A | 1 |
| Moody, AJ | 2 |
| Bloom, SR; Christofides, ND; Fitzpatrick, ML; Modlin, IM | 1 |
| Jacobsen, H; Moody, AJ; Orci, L; Ravazzola, M; Siperstein, A; Sundby, F | 1 |
| Cotton, PB; Kannan, V; Nabarro, JD | 1 |
| Becker, HD; Börger, HW; Schafmayer, A | 1 |
| Marks, V | 1 |
| Aynsley-Green, A; Bloom, SR; Lucas, A | 2 |
| Kumahara, Y; Matsuyama, T; Sawazaki, N; Shima, K; Tanaka, R; Tarui, S | 1 |
| Berzins, R; Manns, JG | 1 |
| Biedziński, TM | 1 |
| Matsuyama, T; Nonaka, K; Shima, K; Tanaka, R; Tarui, S | 1 |
| Lechago, J | 1 |
| Fehmann, HC; Habener, JF | 3 |
| Göke, B; Göke, R; Oltmer, B; Sheikh, SP | 1 |
| Habener, JF; Holz, GH; Kuhtreiber, WM | 1 |
| Ahrén, B; Efendic, S; Gutniak, M; Holst, JJ; Orskov, C | 1 |
| Matsuno, S; Naito, H; Rahman, MM; Sasaki, I; Takahashi, M | 1 |
| Blázquez, E; Toledano, A; Uttenthal, LO | 1 |
| Bataille, D; Demirpence, E; Gros, L; Jarrousse, C; Kervran, A | 1 |
| Itoh, H; Komatsu, R; Kono, N; Matsumura, T; Matsuyama, T; Matsuzawa, Y; Namba, M; Oda, Y; Tanaka, M; Watanabe, N | 1 |
| Fabrizio, T | 1 |
| Holst, JJ; Orskov, C | 2 |
| Bartels, E; Creutzfeldt, W; Ebert, R; Nauck, MA; Orskov, C | 2 |
| Kawai, K; Ohashi, S; Suzuki, S; Watanabe, Y; Yamashita, K | 2 |
| Creutzfeldt, W | 4 |
| Fogel, H; Habener, JF; Mojsov, S; Nathan, DM; Schreiber, E | 1 |
| D'Alessio, DA; Ensinck, JW | 1 |
| Aynsley-Green, A; Bloom, SR; Ghatei, MA; Laker, MF; Lawson, GR; Nelson, R | 1 |
| Creutzfeldt, W; Schmidt, WE; Schulze, A; Siegel, EG | 1 |
| Fukuda, M; Hotta, M; Ikegami, H; Morimoto, S; Ogihara, T; Shima, K | 1 |
| Barthel, M; Ebert, R; Köhler, H; Nustede, R; Schafmayer, A; Schröter-Printzen, I | 1 |
| Bloom, SR; Fuller, CR; Ghatei, MA; Lund, PK; Rountree, DB; Selub, S; Ulshen, MH | 1 |
| Blackmore, PF; Exton, JH; Habener, JF; Mojsov, S | 1 |
| Fehmann, HC; Göke, B; Göke, R | 1 |
| Orskov, C; Poulsen, SS | 1 |
| Deelder, AM; Li, Z; Qi, Z; Su, X | 1 |
| Bloom, SR; Domin, J; Ghatei, MA; Kanse, S; Kreymann, B | 1 |
| Bataille, D; Estival, A; Jarrousse, C; Le Quellec, A; Martinez, J; Pradayrol, L; Sladeczek, F; Tani, T | 1 |
| Arnold, R; Fehmann, HC; Göke, B; Göke, R; Richter, G; Trautmann, ME; Weber, V | 1 |
| Hayashi, H; Nakanishi, I; Ooi, A | 1 |
| Arnold, R; Bächle, R; Fehmann, HC; Göke, B; Göke, R; Wagner, B | 1 |
| Classen, M; Fürlinger, C; Janczewska, I; Schepp, W; Schmidtler, J; Schusdziarra, V; Weigert, N | 1 |
| Hisatomi, A; Inoue, K; Nawata, H; Umeda, F | 1 |
| Eguchi, H; Fukase, N; Manaka, H; Sasaki, H; Sekikawa, A; Suda, K; Takahashi, H; Tominaga, M | 1 |
| Bloom, SR; Ghatei, MA; Goodlad, RA; Wright, NA | 1 |
| Fält, K; Hahn, HJ; Madsen, O; Reiher, H; von Dorsche, HH | 1 |
| Ahrén, B; Fridolf, T | 3 |
| Kawai, K; Koizumi, F; Ohashi, S; Ohneda, A; Ohneda, K; Ohneda, M; Suzuki, S | 1 |
| Elliott, R; Marks, V; Morgan, L; Oben, J | 1 |
| Arnold, R; Göke, B; Göke, R; Richter, G; Schmidt, H | 1 |
| Brighenti, L; Fabbri, E; Gavioli, ME; Ottolenghi, C; Puviani, AC | 1 |
| Andrews, PC; Conlon, JM; Moon, TW; Thim, L | 1 |
| Ahrén, B; Böttcher, G; Fridolf, T; Sundler, F | 1 |
| Holst, JJ; Kotzerke, J; Meyer, HJ; Miholic, J; Orskov, C | 1 |
| Fletcher, J; Marks, V; Morgan, L; Oben, J | 1 |
| Christiansen, J; Hint, K; Holst Pedersen, J; Holst, JJ; Krarup, T; Palmgren, N | 1 |
| Asa, SL; Brubaker, PL; Drucker, DJ; Silverberg, J | 1 |
| Greco, AV; Mancinelli, R; Mingrone, G; Racanicchi, C | 1 |
| Ito, H; Nakayama, H; Tahara, E; Yasui, W; Yoshida, K | 1 |
| Andrews, PC; Cheung, R; Plisetskaya, EM; Youson, JH | 1 |
| Mommsen, TP; Sheridan, MA | 1 |
| Faulkner, A | 1 |
| Ebert, R | 1 |
| Kawai, K; Mukai, H; Murayama, Y; Ohashi, S; Suzuki, S; Yamashita, K | 1 |
| Gefel, D; Habener, J; Hendrick, GK; Mojsov, S; Weir, GC | 1 |
| Arnold, R; Göke, B; Göke, R; Richter, G | 3 |
| Conlon, JM; Creutzfeldt, W; Gallwitz, B; Schmidt, WE | 1 |
| Kawai, K; Murayama, Y; Ohashi, S; Suzuki, S; Yamashita, K | 1 |
| Cha, T; Hirota, M; Ikegami, H; Noma, Y; Ogihara, T; Ohboshi, C; Tahara, Y; Yamamoto, Y; Yamato, E; Yoneda, H | 1 |
| Drucker, DJ | 4 |
| Borrebaek, B; Ceh, L; Dahle, HK; Halse, K; Tveit, B | 1 |
| Aulehner, R; Classen, M; Schmid, R; Schusdziarra, V; Weigert, N | 1 |
| Arnold, R; Fehmann, HC; Göke, B; Göke, R | 2 |
| Bataille, D; Blache, P; Dubrasquet, M; Kervran, A; Martinez, J | 1 |
| Kawai, K; Mukai, H; Murayma, Y; Ohashi, S; Suzuki, S; Yamashita, K | 1 |
| Tarui, S | 1 |
| Shima, K | 2 |
| Bloom, SR; Ghatei, MA; Kreymann, B; Nikou, GC; O'Halloran, DJ | 1 |
| Eckhauser, FE; Strodel, WE; Thompson, NW; Vinik, AI | 1 |
| Han, VK; Hynes, MA; Jin, C; Lauder, JM; Lund, PK; Towle, AC | 1 |
| Bataille, D | 1 |
| Brubaker, PL | 2 |
| Adrian, TE; Bloom, SR; Domschke, S; Domschke, W; Lux, G | 1 |
| Hoshino, M; Iguchi, K; Mochizuki, T; Yanaihara, C; Yanaihara, N; Zhang, T | 1 |
| Cole, T; Conlon, JM; Göke, R | 1 |
| Arnold, R; Fehmann, HC; Göke, B; Göke, R; Haus, E; Richter, G; Trautmann, ME | 1 |
| Arnold, R; Göke, B; Göke, R; Richter, G; Trautmann, M | 1 |
| Kawai, K; Mukai, H; Murayama, Y; Ohashi, S; Ohmori, H; Suzuki, S; Yamashita, K | 1 |
| Mommsen, TP; Plisetskaya, EM; Sheridan, MA | 1 |
| Gilon, P; Remacle, C | 1 |
| Horita, M; Ishimatsu, T; Iwashita, K; Kodama, M; Ono, J; Oribe, Y; Sato, Y; Shigematsu, S; Shimoyama, N; Takaki, R | 1 |
| Gespach, C; Hansen, A; Holst, J | 1 |
| Corigliano-Murphy, AC; Ip, NY; Pisano, JJ; Schwarzschild, MA; Vale, W; Zigmond, RE | 1 |
| Fehmann, HC; Göke, B; Göke, R; Richter, G; Trautmann, M | 1 |
| D'Alessio, DA; Ensinck, JW; Fujimoto, WY | 1 |
| Itoh, H; Komatsu, R; Kono, N; Matsuyama, T; Namba, M; Ohara, T; Shinomura, Y; Tarui, S; Watanabe, N | 1 |
| Habener, JF; Hendrick, GK; Mojsov, S; Weir, GC | 1 |
| Gorbman, A; Mommsen, TP; Ottolenghi, C; Plisetskaya, EM; Sheridan, MA | 1 |
| Hayakawa, T; Kitagawa, M; Kondo, T; Nagai, K; Okumura, N; Shibata, T | 1 |
| Itoh, H; Komatsu, R; Kono, N; Matsuyama, T; Namba, M; Tarui, S; Watanabe, N | 1 |
| Arnold, R; Fehmann, HC; Göke, B; Göke, R; Trautmann, ME | 1 |
| Kawai, K; Mukai, H; Ohashi, S; Suzuki, S; Yamashita, K | 1 |
| Hirota, M; Ohboshi, C; Shima, K; Yoshimoto, S | 1 |
| Bloom, SR; Ghatei, MA; Hubalek, K; Polak, JM; Seitz, HK; Simanowski, UA | 1 |
| Bloom, SR; Burnet, P; Diani, AR; Ghatei, MA; Kanse, S; Kreymann, B; Williams, G | 1 |
| Conlon, JM; Göke, R | 1 |
| Brown, JC; Gee, JM; Johnson, IT | 1 |
| Baldissera, FG; Hilsted, L; Holst, JJ; Knuhtsen, S; Nielsen, OV | 1 |
| Bloom, SR; Ghatei, MA; Kanse, SM; Kreymann, B | 1 |
| Calvo, G; Ghiglione, M; Pascual, JM; Rovira, A; Valverde, I | 1 |
| Bataille, D; Bodéré, H; Chastre, E; Emami, S; Gespach, C; Rosselin, G | 1 |
| Bataille, D; Mercier, F; Nezelof, C; Rousseau-Merck, MF | 1 |
| Rosselin, G | 1 |
| Andrews, PC; Gurd, RS; Hoosein, NM; Mahrenholz, AM | 1 |
| Chick, WL; Drucker, DJ; Habener, JF; Mojsov, S; Philippe, J | 1 |
| Gorbman, A; Miyata, K; Nozaki, M; Oota, Y; Plisetskaya, EM | 1 |
| Andrews, PC; Lee, TD; Nichols, R | 1 |
| Ohneda, A; Ohneda, M | 1 |
| Ginier, P; Levin, SR; Soon-Shiong, P; Swafford, G | 1 |
| Kobayashi, T; Nihei, J; Ohneda, A; Takahashi, H | 1 |
| Itoh, H; Komatsu, R; Matsuyama, T; Namba, M; Tarui, S; Watanabe, N | 1 |
| Matsui, T | 1 |
| Baldissera, FG; Christiansen, J; Holst, JJ; Mortensen, PE; Schjoldager, BT | 1 |
| Bataille, D; Blache, P; Kervran, A; Martinez, J | 1 |
| Bataille, D; Blache, P; Kervran, A | 2 |
| Bloom, SR; Ghatei, MA; Kanse, S; Kreymann, B; Williams, G; Yiangou, Y | 1 |
| Gehl, J; Holst, JJ; Jeppesen, JL; Poulsen, SS | 1 |
| Ebner, KE; Hamilton, JW; Pollock, HG; Rawitch, AB; Rouse, JB | 1 |
| Imamura, M; Sasaki, I; Sato, T; Takahashi, M; Yamauchi, H | 1 |
| Ebner, KE; Hamilton, JW; Kimmel, JR; Lance, V; Pollock, HG; Rawitch, AB; Rouse, JB | 1 |
| Chiba, Y; Kawai, K; Mukai, H; Munekata, E; Yamashita, K | 1 |
| Honda, M; Ikeda, T; Ito, Y; Mashiba, H; Mokuda, O; Tominaga, M; Yoshida, T | 1 |
| Conlon, JM; Dafgård, E; Falkmer, S; Thim, L | 1 |
| Eriksson, M; Lindén, A; Uvnäs-Moberg, K | 1 |
| Brubaker, PL; Vranic, M | 1 |
| Itoh, H; Komatsu, R; Kono, N; Matsuyama, T; Miyagawa, J; Namba, M; Tarui, S; Watanabe, N | 1 |
| Han, VK; Jin, SL; Lauder, JM; Lund, PK; Simmons, JG; Towle, AC | 1 |
| Hornnes, PJ; Kühl, C | 1 |
| Fujiwara, M; Hashimoto, M; Higashi, T; Kobayashi, M; Nagashima, H; Nakatsukasa, H; Watanabe, A; Watanabe, M; Yamauchi, Y | 1 |
| Beylot, M; Chayvialle, JA; Cohen, R; Mornex, R; Rebattu, B; Riou, JP; Sautot, G | 1 |
| Gorbman, A; Hamilton, JW; Kimmel, JR; Plisetskaya, E; Pollock, HG; Rouse, JB | 1 |
| Hinshaw, LB; Ishida, K | 1 |
| Fujiwara, M; Nagashima, H; Watanabe, A | 1 |
| Kobayashi, T; Nihei, J; Ohneda, A | 2 |
| Bataille, D; Depigny, C; Dubrasquet, M; Jarrousse, C; Kervran, A | 1 |
| Drucker, DJ; Habener, JF; Mojsov, S; Philippe, J | 1 |
| Habener, JF; Mojsov, S; Weir, GC | 1 |
| Creutzfeldt, W; Ebert, R | 2 |
| Conlon, JM; O'Toole, L; Thim, L | 1 |
| Funayama, Y; Naito, H; Ohneda, A; Sasaki, I; Sato, T; Suzuki, Y; Toda, M; Tuchiya, T | 1 |
| Oka, H | 1 |
| Gregor, M; Menge, H; Riecken, EO; Stössel, R | 1 |
| Meryn, S; Stein, D; Straus, EW | 1 |
| Lund, PK; Vaillant, CR | 1 |
| Hase, T; Inokuchi, A; Kimura, H; Matsumoto, T; Oomura, Y; Tomida, Y; Yanaihara, C; Yanaihara, N; Yui, R | 1 |
| Horie, H; Imai, Y; Itoh, H; Matsuyama, T; Namba, M; Tarui, S | 1 |
| Garrote, FJ; Herrera Pombo, JL; Pascual, JM; Rovira, A; Salvador, MG; Valverde, I | 1 |
| Andrews, PC; Ronner, P | 1 |
| Fussgänger, R; Maier, V; Pfeiffer, EF; Wójcikowski, C | 1 |
| Baldissera, FG; Holst, JJ; Poulsen, K | 1 |
| Gregor, M; Riecken, EO | 1 |
| Peeze Binkhorst, FM; Rombout, JH; Taverne-Thiele, JJ | 1 |
| Capella, C; Fiocca, R; Rindi, G; Schwartz, TW; Sessa, F; Solcia, E; Usellini, L; Yanaihara, N | 1 |
| Bacarese-Hamilton, AJ; Bloom, SR; Ghiglione, M; Rolston, R; Uttenthal, LO | 1 |
| Sasaki, H | 1 |
| Aynsley-Green, A | 1 |
| Christiansen, J; Holst, JJ; Petersen, B | 1 |
| Bacarese-Hamilton, AJ; Bloom, SR; Ovington, KS | 1 |
| Adrian, TE; Baron, JH; Bloom, SR; El-Sabbagh, HN; Prinz, RA; Welbourn, RB | 1 |
| Neumayr, A | 1 |
| Bataille, D; Dubrasquet, M; Gespach, C | 1 |
| Jablonská, M | 1 |
| Cohen, L; Foltzer, C; Mialhe, P; Strosser, MT | 1 |
| Matsuyama, T | 2 |
| Germaniuk, IaL | 1 |
| Ince, BW; So, ST | 1 |
| Lickley, HL; Vranic, M; Wasserman, DH | 1 |
| Groza, P | 1 |
| Matsumoto, T; Mochizuki, T; Yamamoto, E; Yanaihara, C; Yanaihara, N | 1 |
| Holst, JJ | 6 |
| Adrian, TE; Blank, MA; Bloom, SR; Ghatei, MA; Langevin, H; Lee, YC; McGregor, GP; O'Shaughnessy, DJ; Uttenthal, LO | 1 |
| Brown, JC | 1 |
| Charles, MA; Waldeck, N | 1 |
| Bataille, D; Coudray, AM; Gespach, C; Rosselin, G | 1 |
| Björntorp, P | 1 |
| Bataille, D; Coudray, AM; Gespach, C; Marie, JC; Mutt, V; Rosselin, G; Tatemoto, K | 1 |
| Fukushima, H; Uzawa, H; Yamaguchi, K | 1 |
| Burger, Z; Guoth, J; Guoth, M; Korányi, L; Péterfy, F; Tamás, G | 1 |
| Bloom, SR; Cassar, J; Ghatei, MA; Joplin, GF; Mashiter, K; Sarson, DL | 1 |
| Andersen, B; Holst, JJ; Lauritsen, KB; Stadil, F; Sørensen, TI | 1 |
| Bassett, JM; Bell, AW; Boston, RC; Chandler, KD | 1 |
| Lauritsen, KB | 1 |
| Nagulesparan, M; Unger, RH; Vasquez, B | 1 |
| Creutzfeldt, W; Ebert, R; Unger, H | 1 |
| Akerblom, HK; Knip, M; Kouvalainen, K; Lautala, P; Leppäluoto, J | 1 |
| Hyakkoku, B; Kihara, A | 1 |
| Ansorge, S; Bernstein, HG; Dorn, A; Hahn, HJ; Rinne, A; Ziegler, M | 1 |
| Akerblom, HK; Knip, M; Kouvalainen, K; Lautala, P; Martin, JM | 1 |
| Beck-Nielsen, H; Holst, JJ; Lovgreen, NA; Pedersen, O; Schwartz, TW | 1 |
| Bataille, D; Jarrousse, C; Jeanrenaud, B | 1 |
| Marks, V; Tsiolakis, D | 1 |
| Akiyama, H; Iwasaki, M; Izima, N; Kameya, S; Ohdate, K; Yoshioka, S | 1 |
| Allen, PC; McMurtry, JP | 1 |
| Märki, F | 1 |
| Levy, N; Stermer, E | 1 |
| Daikuhara, Y; Fujisaki, K; Gohda, E; Hashimoto, S; Hirono, S; Kamibeppu, A; Miyazaki, H; Nagahama, J; Oka, H; Tsubouchi, H | 1 |
| Tsubouchi, H | 1 |
| Baile, CA; Gingerich, RL; McLaughlin, CL | 1 |
| Baldissera, FG; Holst, JJ | 1 |
| Kamimura, T; Kaneda, H; Katagiri, T; Marubashi, S; Sasaki, H; Tominaga, M | 1 |
| Bernstein, HG | 1 |
| Akai, H; Goto, Y; Imai, N; Nagasaki, A; Nakanome, C; Toyota, T | 1 |
| Frazier, ML; Li, WH; Lopez, LC; Luo, CC; Saunders, GF | 1 |
| Aggestrup, S; Holst, JJ; Loud, FB; Olesen, M | 1 |
| Alam, MJ; Buchanan, KD; McConnell, JG; O'Hare, MM; Stout, RW | 1 |
| Bailey, CJ; Flatt, PR; Swanston-Flatt, SK | 1 |
| Ishikawa, Z; Kihara, A; Momoishi, B; Nojiri, Y; Tada, N | 1 |
| Kondo, M | 1 |
| Badía, A; Herrera Pombo, JL; Rovira, A; Valverde, I; Vázquez, C; Vázquez, J | 1 |
| Tsutsumi, Y; Watanabe, K | 1 |
| Christensen, KC; Lauritsen, KB; Lauritzen, JB | 1 |
| Adrian, TE; Besterman, HS; Bloom, SR; Christofides, ND; Guerin, S; Lombardo, L; Mallinson, CN; Modigliani, R; Ponti, V; South, M | 1 |
| Knip, M; Mäkäräinen, L; Pakarinen, A; Viinikka, L; Ylikorkala, O | 1 |
| Bataille, D; Coudray, AM; Mutt, V; Rosselin, G; Tatemoto, K | 1 |
| Bloom, SR; Bryant, MG; Christofides, ND; Ghatei, MA; Uttenthal, LO | 1 |
| Conlon, JM | 1 |
| Moody, AJ; Thim, L | 3 |
| Khemiss, F; Sitbon, G | 1 |
| Ghiglione, M; López-Novoa, JM; Matesanz, R; Pascual, JM; Rovira, A; Valverde, I; Zubiaur, M | 1 |
| Dutczak, M; Hatton, TW; Kovacevic, N; Vranic, M | 1 |
| Cockburn, E; Siu, KP; Tung, AK | 1 |
| Fukuda, M; Ishimoto, I; Kuwayama, Y; Shimizu, Y; Tohyama, M | 1 |
| Franchimont, C; Gerard, J; Lapiere, CM; Luyckx, AS; Pierard, GE | 1 |
| Imagawa, K; Kodaira, T; Kumahara, Y; Nishino, T; Shima, K; Shin, S; Yanaihara, N | 1 |
| Bansal, DD; Buchanan, KD; Carlin, AJ; Elmore, DT; Ewing, AS; Irvine, GB; McKibben, B; Murphy, RF | 1 |
| Orci, L; Ravazzola, M | 1 |
| Holst, JJ; Hornnes, PJ; Kühl, C; Lauritsen, KB; Rehfeld, JF; Schwartz, TW | 1 |
| Aune, S; Kåresen, R; Tronier, B | 1 |
| Larsson, LI; Moody, AJ | 1 |
| Becker, HD | 1 |
| Levin, SR | 1 |
| Eloy, R; Garaud, JC; Grenier, JF; Moody, AJ; Stock, C | 1 |
| Ahrén, B; Lundquist, I | 1 |
| Hornnes, PJ; Kühl, C; Lauritsen, KB | 1 |
| Buchanan, KD; Carson, DJ; Glasgow, JF; Sloan, JM | 1 |
| Bloom, SR; Dupre, J; Ghatei, MA; McDonald, TJ; Mutt, V; Radziuk, J; Track, NS | 1 |
| Bloom, SR; Demling, L; Domschke, S; Domschke, W | 1 |
| Besterman, HS; Bloom, SR; Dammann, HG; Schreiber, HW | 1 |
| Kodaira, T; Kumahara, Y; Nishino, T; Shima, K; Tabata, M; Tanaka, A | 1 |
| Bode, HP; Göke, B; Göke, R; Lankat-Buttgereit, B; van Eyll, B | 1 |
| Koivisto, V | 1 |
| Ebner, K; Fürnsinn, C; Waldhäusl, W | 1 |
| Alcántara, A; Clemente, F; Delgado, E; Luque, MA; Perea, A; Trapote, MA; Valverde, I; Villanueva-Peñacarrillo, ML | 1 |
| Chayvialle, JA; Cuber, JC; Dakka, T; Dumoulin, V; Plaisancie, P | 1 |
| Dissing, S; Gromada, J; Rorsman, P; Wulff, BS | 1 |
| Martin, S; Rouillé, Y; Steiner, DF | 1 |
| Creutzfeldt, W; Holst, JJ; Nauck, MA; Orskov, C; Qualmann, C | 1 |
| Hasumi, S; Kawai, K; Kuroki, H; Maruyama, A; Miyazono, Y; Omori, Y; Owada, K; Wasada, T; Yano, K; Yoshino, H | 1 |
| Kieffer, TJ; McIntosh, CH; Pederson, RA | 1 |
| Chayvialle, JA; Cuber, JC; Dumoulin, V; Plaisancié, P | 1 |
| Deacon, CF; Holst, JJ; Nauck, MA; Pridal, L; Toft-Nielsen, M; Willms, B | 1 |
| Hargrove, DM; Nardone, NA; Parker, JC; Persson, LM; Stevenson, RW | 1 |
| Holst, JJ; Nauck, MA; Orskov, C; Ritzel, R | 1 |
| Harling, H; Holst, JJ; Rasmussen, TN; Schmidt, P | 1 |
| Göke, B; Göke, R; McGregor, GP | 2 |
| el-Salhy, M; Grimelius, L; Stenling, R | 1 |
| Bloom, SR; Ghatei, MA; Kruszynska, YT; McIntyre, N | 1 |
| Okuda, Y; Yamashita, K | 1 |
| Elliott, R; Jia, X; Kwok, YN; McIntosh, CH; Pederson, RA | 1 |
| Brown, JC; Jia, X; Ma, P; McIntosh, CH; Pederson, RA | 1 |
| Arnold, R; Fehmann, HC; Göke, B; Göke, R; Herrmann, C; Richter, G | 1 |
| Bridenbaugh, S; Fieseler, P; Holst, JJ; Martell, J; Nauck, MA; Nustede, R; Orskov, C | 1 |
| Amano, N; Koyama, N; Kuriyama, M; Nishimura, O | 1 |
| Bataille, D; Gros, L; Hollande, F; Kervran, A; Thorens, B | 1 |
| Alcántara, A; Clemente, F; Delgado, E; Galera, C; Luque, MA; Trapote, MA; Valverde, I; Villanueva-Peñacarrillo, ML | 1 |
| Bokvist, K; Dissing, S; Frøkjaer-Jensen, J; Gromada, J; Renström, E; Rorsman, P; Wulff, BS | 1 |
| Blázquez, E; Calvo, JC; Mora, F; Yusta, B | 1 |
| Fehmann, HC; Göke, B; Göke, R; Kolligs, F | 1 |
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| Bloom, SR; Ghatei, MA; Owji, AA; Smith, DM; Wang, RM; Wang, Z | 1 |
| Classen, M; Dehne, K; Eng, J; Holst, JJ; Raufman, JP; Riedel, T; Schepp, W; Schmidtler, J; Schusdziarra, V | 1 |
| Deacon, S; Elliott, RM; Marks, V; Morgan, LM; Tredger, JA; Wright, J | 1 |
| Nagasaki, T; Ohneda, A; Ohneda, K; Sasaki, K | 1 |
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| Fletcher, JM; Knapper, JM; Morgan, LM; Puddicombe, SM | 1 |
| Kuwajima, M; Matsumura, T; Matsuzawa, Y; Mineo, I; Namba, M; Shingu, R | 1 |
| Alcántara, AI; Clemente, F; Delgado, E; Valverde, I; Villanueva-Peñacarrillo, ML | 1 |
| Brown, JC; Jia, X; Kwok, YN; McIntosh, CH; Pederson, RA | 1 |
| Potter, IC; Youson, JH | 1 |
| Fehmann, HC; Göke, B; Strowski, M | 1 |
| Arnold, R; Bothe-Sandfort, E; Eissele, R; Eng, J; Göke, B; Koop, H | 1 |
| Christiansen, J; Holst, JJ; Orskov, C; Petersen, H; Sheikh, SP; Wettergren, A | 1 |
| Boyd, AE; Fehmann, HC; Göke, B; Jiang, J; Schweinfurth, J; Wheeler, MB | 1 |
| Göke, B; Göke, R; Just, R; Lankat-Buttgereit, B | 1 |
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| Allescher, HD; Classen, M; Dehne, K; Holst, JJ; Polack, A; Schepp, W; Schmidtler, J; Schusdziarra, V | 1 |
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| Clemente, F; Delgado, E; López-Delgado, MI; Morales, M; Perea, A; Valverde, I; Villanueva-Peñacarrillo, ML | 1 |
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| Bataille, D; Gros, L; Kervran, A; Thorens, B | 1 |
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| Bataille, D; Blache, P; Boegner-Lemoine, C; Cohen-Solal, A; Kervran, A; Le-Nguyen, D | 1 |
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| Classen, M; Dehne, K; Offermanns, S; Rosenthal, W; Schepp, W; Schmidtler, J | 1 |
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| Delgado, E; Mérida, E; Molina, LM; Valverde, I; Villanueva-Peñacarrillo, ML | 1 |
| Bonet, H; Codoceo, R; de Miguel, E; Gómez de Segura, IA; Mata, A; Rodríguez Montes, JA | 1 |
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| Thorens, B; Waeber, G | 1 |
| Fletcher, JM; Knapper, JM; Marks, V; Morgan, LM; Puddicombe, SM | 1 |
| Delgado, E; Mérida, E; Trapote, MA; Valverde, I; Villanueva-Peñacarrillo, ML | 1 |
| Boyd, AE; Leng, XH; Lu, M; Wheeler, MB | 1 |
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| Boyd, AE; Chen, C; Dillon, JS; Leng, XH; Lu, M; Wheeler, MB | 1 |
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| Eng, J; Fehmann, HC; Göke, B; Göke, R; Krause, M; Linn, T; Schmidt, H | 1 |
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| Chen, C; Hosokawa, H; Hosokawa, YA; Leahy, JL | 1 |
| Arnold, R; Göke, B; Katschinski, M; Schäfer, T; Schirra, J; Wank, U; Weidmann, C | 1 |
| Adelhorst, K; Holst, JJ; Ingwersen, SH; Kirk, O; Larsen, FS; Pridal, L | 1 |
| Göke, R; Larsen, PJ; Mikkelsen, JD; Sheikh, SP | 1 |
| Fletcher, JM; Heath, A; Knapper, JM; Marks, V; Morgan, LM | 1 |
| Kim, Y; Rose, CA | 1 |
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| Bridenbaugh, R; Göke, B; Göke, R; Hupe-Sodmann, K; McGregor, GP; Thole, H; Voigt, K; Zimmermann, B | 1 |
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| Haren, AM; Kim, Y | 1 |
| Brasseur, R | 1 |
| Andrews, KM; Hargrove, DM; Nardone, NA; Parker, JC; Persson, LM; Shepherd, KL; Stevenson, RW | 1 |
| Gyomorey, S; Li, X; Mathi, SK; Su, RC; Takhar, S; Wheeler, MB | 1 |
| Holst, JJ; Møller, M; Orskov, C; Poulsen, SS | 1 |
| Brubaker, PL; Gronau, KA; Roberge, JN | 1 |
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| Bloom, SR; Fuller, CR; Ghatei, MA; Hoyt, EC; Lund, PK; Ulshen, MH | 1 |
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| Brubaker, PL; Dhanvantari, S; Seidah, NG | 1 |
| Creutzfeldt, WO; Holst, JJ; Kleine, N; Nauck, MA; Orskov, C; Willms, B | 1 |
| Beak, SA; Bloom, SR; Gunn, I; O'Shea, D; Turton, MD | 1 |
| Brubaker, PL; Dhanvantari, S; Tucker, JD | 1 |
| Frölich, M; Gooszen, HG; Guicherit, OR; van der Burg, MP | 1 |
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| Fletcher, JM; Knapper, JM; Marks, V; Morgan, LM | 1 |
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| Gama, R; Hampton, S; Marks, V; Morgan, L; Norris, F; Watkins, S; Wright, J | 1 |
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| Kawai, K; Nakagawa, Y; Ohashi, S; Suzuki, H; Yamashita, K | 1 |
| Fink-Jensen, A; Göke, R; Jessop, DS; Larsen, PJ; Møller, M; Sheikh, SP; Tang-Christensen, M | 1 |
| Bernstein, IL; Burn, P; Campfield, LA; Donahey, JC; Seeley, RJ; Smith, FJ; Thiele, TE; Van Dijk, G; Woods, SC | 1 |
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| Beety, JM; Howland, R; Marks, V; Morgan, LM; Ranganath, LR; Wright, JW | 1 |
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| Bataille, D; Bergeron, F; Blache, P | 1 |
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| Bernstein, IL; Seeley, RJ; Thiele, TE; van Dijk, G; Woods, SC | 1 |
| Deeg, MA; Verchere, CB | 1 |
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| Holst, JJ; Keller, U; Shalev, A | 1 |
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| Berghöfer, P; Fehmann, HC; Göke, B; Peterson, RG; Schneider, K | 1 |
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| Buschard, K; Ding, WG; Gromada, J; Renström, E; Rorsman, P | 1 |
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| Göke, B; Göke, R; Hupe-Sodmann, K; McGregor, GP; Thole, HH; Voigt, K; Zimmermann, B | 1 |
| Brubaker, PL; Cooper, S; Crivici, A; DeForest, L; Drucker, DJ; Hill, M; Shi, Q; Sumner-Smith, M; Tavares, W | 1 |
| Alcántara, A; Clemente, F; López-Delgado, MI; Luque, MA; Malaisse, WJ; Márquez, L; Morales, M; Puente, J; Valverde, I; Villanueva-Peñacarrillo, ML; Viñambres, C | 1 |
| Barg, S; Ding, WG; Gromada, J; Renström, E; Rorsman, P | 1 |
| Andersen, K; Astrup, A; Holst, JJ; Karberg, MA; Raben, A | 1 |
| Bloom, SR; Edwards, AV; Edwards, CM | 1 |
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| Dobashi, Y; Kanno, T; Suga, S; Wakui, M | 1 |
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| Adams, LG; Montrose, MH; Montrose-Rafizadeh, C; Roth, J; Wang, Y; Yang, H | 1 |
| Bianchi, M; Halban, PA; Irminger, JC; Rouillé, Y | 1 |
| Bali, JP; Bataille, D; Jarrousse, C; Magous, R; Martinez, J; Mochizuki, T; Nguyen, DL; Rodier, G | 1 |
| Jessop, DS; Larsen, PJ; Tang-Christensen, M | 1 |
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| Dobashi, Y; Kanno, T; Nakano, K; Suga, S; Takeo, T; Wakui, M | 1 |
| Brubaker, PL; Dhanvantari, S; Drucker, DJ; Fischer, KD | 1 |
| Brosnan, JT; Mabrouk, GM | 1 |
| Clemente, F; Perea, A; Valverde, I; Villanueva-Peñacarrillo, ML; Viñambres, C | 1 |
| Bergman, T; Chen, ZW; Efendic, S; Jörnvall, H; Mutt, V; Ostenson, CG | 1 |
| Ettler, R; Holst, JJ; Nauck, MA; Niedereichholz, U; Orskov, C; Ritzel, R; Schmiegel, WH | 1 |
| Lucius, R; Mentlein, R | 1 |
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| Kuwajima, M; Matsuyama, T | 1 |
| Abdel-Wahab, YH; Flatt, PR; Gray, AM; O'Harte, FP | 1 |
| Gama, R; Hampton, S; Marks, V; Morgan, L; Norris, F; Wright, J | 1 |
| Halban, PA; Irminger, JC; Kantengwa, S; Rouillé, Y | 1 |
| Bloom, SR; Gunn, I; O'Shea, D | 1 |
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| Bokvist, K; Ding, WG; Gromada, J; Holst, JJ; Nielsen, JH; Rorsman, P | 1 |
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| Gromada, J; Holst, JJ; Rorsman, P | 1 |
| Arnold, R; Beglinger, C; Göke, B; Hildebrand, P; Katschinski, M; Leicht, P; Schirra, J | 1 |
| Brubaker, PL; Dhanvantari, S | 1 |
| Deacon, CF; Holst, JJ; Jacobsen, O; Knudsen, LB; Madsen, K; Wiberg, FC | 1 |
| Boyd, AE; Dillon, JS; Leng, XH; Ligon, BB; Wheeler, MB | 1 |
| Nakata, M; Tanaka, H; Yada, T; Yaekura, K | 1 |
| Compton, DS; Davis, HR; France, CF; Graziano, MP; Hoos, LM; Mullins, DE; Pines, JM; Strader, CD; Sybertz, EJ; Van Heek, M | 1 |
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| Matsuno, S; Naito, H; Sasaki, I | 1 |
| Benito, E; Blazquez, E; Bosch, MA | 1 |
| Larsen, PJ; Tang-Christensen, M; Vrang, N | 3 |
| Keller, U; Ninnis, R; Shalev, A | 1 |
| Luque, MA; Márquez, L; Trapote, MA; Valverde, I; Villanueva-Peñacarrillo, ML | 1 |
| Bloom, SR; Brynes, AE; Edwards, CM; Frost, GS; Ghatei, MA | 2 |
| Bergmann, J; Holst, JJ; Nauck, MA; Ritzel, R; Schmiegel, W; Seifarth, C | 1 |
| Egan, JM; Elahi, D; Habener, JF; Ryan, AS | 1 |
| Holst, JJ; Wettergren, A; Wøjdemann, M | 2 |
| McBurney, MI; Tappenden, KA | 1 |
| Bataille, D; Beauclair, F; Eto, B; Jarrousse, C; Martinez, J; Mochizuki, T; Pansu, D; Rodier, G | 1 |
| Bernstein, IL; D'Alessio, D; Eng, J; Seeley, RJ; Thiele, TE; van Dijk, G; Woods, SC | 1 |
| Boissart, C; Leclercq-Meyer, V; Malaisse, WJ; Pessah, M; Rosselin, G | 1 |
| Hansen, BF; Jensen, P; Nepper-Christensen, E; Skjølstrup, B | 1 |
| Asarian, L; Corp, ES; Geary, N; Hrupka, B | 1 |
| Agulleiro, B; García-Hernández, MP; Gómez-visus, I; Lozano, MT | 1 |
| Bungo, T; Furuse, M; Hasegawa, S; Masuda, Y; Saito, N; Shimojo, M; Sugahara, K | 2 |
| Gutniak, M | 1 |
| Flier, ES; Gillette, J; Ludwig, DS; Maratos-Flier, E; Tritos, NA; Vicent, D | 1 |
| Abdel-Wahab, YH; Conlon, JM; Flatt, PR; O'Harte, FP | 1 |
| Eckart, K; Leonhardt, U; Ottleben, M; Ramadori, G; Ritzel, U; Rühmann, A; Spiess, J | 1 |
| Hunger, A; Jungermann, K; Scholtka, B; Stümpel, F | 1 |
| Holst, JJ; Pridal, L; Wettergren, A; Wøjdemann, M | 1 |
| Bach, I; Holst, JJ; Nauck, MA; Orskov, C; Richter, S; Schmiegel, W; Weber, I | 1 |
| Bloom, SR; Edwards, CM; Ghatei, MA; Todd, JF | 1 |
| Marks, V; Morgan, L; Ranganath, L; Sedgwick, I; Wright, J | 1 |
| Alvarez, E; Blázquez, E; Castrillón, PO; Chowen, JA; Esquifino, AI; Zueco, JA | 1 |
| Bali, JP; Bataille, D; Geneviève, R; Jarrousse, C; Le Nguyen, D; Magous, R; Martinez, J; Mochizuki, T; Rodier, G | 1 |
| Abusnana, S; Bloom, SR; Choi, SJ; Edwards, CM; Ghatei, MA; Goldstone, AP; Gunn, I; Heath, MM; Meeran, K; O'Shea, D; Rossi, M; Small, CJ; Steere, J; Sunter, D; Taylor, GM; Turton, MD | 1 |
| Green, J; Leigh, IM; Poulsom, R; Quinn, AG | 1 |
| Andrews, GC; Andrews, KM; Contillo, LG; Massefski, W; Parker, JC; Rescek, DM; Singleton, DH; Stevenson, RW; Suleske, RT | 1 |
| Fukuda, H; Ikeda, H; Iritani, N; Komiya, M; Sugimoto, T | 1 |
| Astesano, A; Boissard, C; Emami, S; Ferrand, N; Garel, JM; Pessah, M; Phan, H; Regnauld, K; Rosselin, G | 1 |
| Bataille, D; Blache, P; Dalle, S; Le Brigand, L; Le-Nguyen, D | 1 |
| Bali, JP; Bataille, D; Jarrousse, C; Magous, R; Mochizuki, T; Rodier, G | 1 |
| Hirotani, Y; Kataoka, K; Kurokawa, N; Luo, WQ; Sasaki, K; Satoh, T; Taki, M; Yanaihara, C; Yanaihara, N | 1 |
| Fukushima, K; Funayama, Y; Kojima, R; Matsuno, S; Naito, H; Ohneda, A; Sasaki, I; Sasaki, K; Sato, T; Shibata, C | 1 |
| Alvarez, E; Blázquez, E; Chowen, JA; Navarro, M; Rodríguez-Fonseca, F; Roncero, I; Zueco, JA | 1 |
| Ber, E; Cascieri, MA; Chicchi, GG; de Laszlo, SE; Hacker, C; Hagmann, WK; Koch, GE; Louizides, D; MacCoss, M; Sadowski, SJ; Vicario, PP | 1 |
| Marks, V; Morgan, L; Norris, F; Ranganath, L; Wright, J | 1 |
| Nauck, MA | 1 |
| Fernandez, J; Valdeolmillos, M | 1 |
| Hampton, SM; Livesey, G; Mathers, JC; Morgan, LM; Robertson, MD | 1 |
| Ashcroft, FM; Bataille, D; Bergeron, F; Blache, P; Dalle, S; Le Brigand, L; Le-Nguyen, D; Smith, P | 1 |
| Brynes, A; Frost, G; Leeds, A | 1 |
| Bardocz, S; Bliss, P; Bloom, SR; Brynes, A; Calam, J; Fitzgerald, A; Ghatei, MA; Goodlad, RA; Grant, G; Jordinson, M; Pignatelli, M; Pusztai, A | 1 |
| Fenselau, S; Hermansen, K; Holst, JJ; Lousen, T; Rasmussen, O; Schrezenmeir, J; Thomsen, C | 1 |
| Tseng, CC; Wolfe, MM; Zhang, XY | 1 |
| Holst, JJ; Hopfenmüller, W; Messerschmidt, D; Plöckinger, U; Quabbe, HJ | 1 |
| Efendic, S; Eskilsson, A; Hassan, M; Jacobsson, H; Jonsson, C; Larsson, S; Nilsson, C; Refai, E | 1 |
| Holst, JJ; Madsbad, S; Toft-Nielsen, MB | 1 |
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| Anini, Y; Chariot, J; Cuber, JC; Fu-Cheng, X; Kervran, A; Roz, C | 1 |
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| Nightingale, J | 1 |
| Gallwitz, B; Schmidt, WE | 1 |
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97 review(s) available for glucagon and oxyntomodulin
| Article | Year |
|---|---|
[Glucagon: modern aspects of clinical interest (author's transl)].
Topics: Acromegaly; Adenoma, Islet Cell; Cholestasis; Diverticulitis; Esophageal Achalasia; Esophageal Perforation; Glucagon; Glucagon-Like Peptides; Glycogen Storage Disease; Hepatitis; Humans; Hypoglycemia; Molecular Weight; Osteitis Deformans; Pancreas; Pheochromocytoma; Thyroid Neoplasms | 1979 |
Effect of vagotomy on gastrointestinal hormones.
Topics: Animals; Cholecystokinin; Dogs; Gastric Inhibitory Polypeptide; Gastrins; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Humans; Insulin; Insulin Secretion; Pancreas; Pancreatic Polypeptide; Peptic Ulcer; Secretin; Somatostatin; Vagotomy | 1979 |
Entero-insular axis and diabetes mellitus.
Topics: Animals; Cholecystokinin; Diabetes Mellitus, Type 2; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Insulin Secretion; Intestines; Islets of Langerhans; Peptide Fragments | 1992 |
Glucagon-like peptide-1(7-36) amide is a new incretin/enterogastrone candidate.
Topics: Animals; Brain; Digestive System; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Humans; Peptide Fragments; Peptides; Proglucagon; Protein Precursors; Protein Processing, Post-Translational; Receptors, Cell Surface; Receptors, Glucagon | 1991 |
Gut hormones in glucose homeostasis.
Topics: Blood Glucose; Gastric Inhibitory Polypeptide; Gastrointestinal Hormones; Glucagon-Like Peptides; Homeostasis; Humans; Insulin; Intestinal Absorption; Peptides | 1991 |
Glucagon and the glucagon-like peptides.
Topics: Animals; Brain; Gene Expression; Glucagon; Glucagon-Like Peptides; Humans; Intestinal Mucosa; Pancreas; Peptides; Proglucagon; Protein Precursors; Protein Processing, Post-Translational | 1990 |
[Enteroglucagons: current status].
Topics: Animals; Base Sequence; Epitopes; Gastrointestinal Hormones; Genes; Glucagon; Glucagon-Like Peptides; Humans; Proglucagon; Protein Precursors; Structure-Activity Relationship | 1987 |
Recent advances in brain-gut hormones.
Topics: Animals; Galanin; Glucagon; Glucagon-Like Peptides; Gonadotropin-Releasing Hormone; Humans; Immunohistochemistry; Peptides; Proglucagon; Protein Precursors; Recombinant Proteins; Recombination, Genetic | 1989 |
[The entero-insular axis: the new incretin candidate glucagon-like peptide-1(7-36)amide (GLP-1(7-36))amide].
Topics: Animals; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Peptide Fragments; Peptides; Rats; Receptors, Cell Surface; Receptors, Glucagon; Structure-Activity Relationship; Swine | 1988 |
Functional receptors for VIP, GIP, glucagon-29 and -37 in the HGT-1 human gastric cancer cell line.
Topics: Adenylyl Cyclases; Cell Line; Cyclic AMP; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptides; Humans; Receptors, Cell Surface; Receptors, Gastrointestinal Hormone; Receptors, Glucagon; Receptors, Vasoactive Intestinal Peptide; Stomach Neoplasms; Vasoactive Intestinal Peptide | 1986 |
The receptors of the VIP family peptides (VIP, secretin, GRF, PHI, PHM, GIP, glucagon and oxyntomodulin). Specificities and identity.
Topics: Animals; Binding Sites; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptides; Growth Hormone-Releasing Hormone; Humans; Models, Biological; Oxyntomodulin; Peptide PHI; Peptides; Protein Precursors; Receptors, Cell Surface; Receptors, Vasoactive Intestinal Peptide; Secretin; Vasoactive Intestinal Peptide | 1986 |
The biological significance of "enteroglucagon." Present status.
Topics: Animals; Digestive System; Gastric Acid; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Organ Specificity; Oxyntomodulin; Proglucagon; Protein Precursors | 1986 |
New developments in the incretin concept.
Topics: Animals; Feedback; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Humans; Insulin; Insulin Secretion; Liver; Peptide Fragments | 1985 |
[Glucagon-related polypeptides in health and disease].
Topics: Diabetes Mellitus; Glucagon; Glucagon-Like Peptides; Humans; Peptides; Radioimmunoassay | 1985 |
Metabolic and endocrine interrelations in the human fetus and neonate.
Topics: Adaptation, Physiological; Amino Acids; Amniotic Fluid; Blood Glucose; Digestive System; Enteral Nutrition; Female; Fetal Blood; Fetus; Gastric Inhibitory Polypeptide; Gastrins; Glucagon; Glucagon-Like Peptides; Hormones; Humans; Infant; Infant Food; Infant, Newborn; Infant, Premature; Maternal-Fetal Exchange; Pancreatic Polypeptide; Pregnancy | 1985 |
[Gastrointestinal glucagons. -- their secretions and roles].
Topics: Animals; Arginine; Bile; Dogs; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Glucose; Half-Life; Humans; Hypotonic Solutions; In Vitro Techniques; Insulin; Pancreatectomy; Radioimmunoassay; Rats; Somatostatin; Tissue Distribution | 1983 |
[Peptide hormones of the digestive organs (review of the literature)].
Topics: Cholecystokinin; Diabetes Mellitus, Type 2; Digestive System Physiological Phenomena; Gastric Inhibitory Polypeptide; Gastrins; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Humans; Insulin; Motilin; Neurotensin; Obesity; Pancreatic Polypeptide; Pentagastrin; Secretin; Somatostatin; Vasoactive Intestinal Peptide | 1983 |
[Digestive hormones. Gastroinhibitory hormones. 2].
Topics: Amino Acid Sequence; Animals; Cholecystokinin; Duodenum; Enkephalins; Epidermal Growth Factor; Gastric Inhibitory Polypeptide; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Humans; Intercellular Signaling Peptides and Proteins; Intestinal Mucosa; Motilin; Neurotensin; Pancreas; Pancreatic Polypeptide; Pepsin A; Peptides; Secretin; Somatostatin; Substance P; Vasoactive Intestinal Peptide | 1981 |
Gut glucagon, enteroglucagon, gut glucagonlike immunoreactivity, glicentin--current status.
Topics: Amino Acid Sequence; DNA; Epitopes; Glucagon; Glucagon-Like Peptides; Intestinal Mucosa; Pancreatic Polypeptide; Peptides; Proglucagon; Protein Precursors; Radioimmunoassay; RNA, Messenger | 1983 |
Gastric inhibitory polypeptide.
Topics: Adipose Tissue; Amino Acid Sequence; Animals; Diabetes Mellitus; Gastric Acid; Gastric Inhibitory Polypeptide; Gastrins; Gastrointestinal Diseases; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Humans; Insulin; Pancreatitis; Pepsin A; Peptide Fragments; Peptides; Proinsulin; Radioimmunoassay; Salivation; Splanchnic Circulation | 1982 |
GIP, incretin and gastrointestinal disease.
Topics: Animals; Blood Glucose; Celiac Disease; Digestive System; Duodenal Ulcer; Gastric Inhibitory Polypeptide; Gastrointestinal Diseases; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Tolerance Test; Humans; Ileum; Insulin; Intestine, Small; Islets of Langerhans; Jejunum; Peptide Fragments; Peptides; Vagotomy | 1983 |
Gastrointestinal peptides--rôle in pathophysiology and disease.
Topics: Autonomic Nervous System; Duodenal Ulcer; Endocrine Glands; Gastric Inhibitory Polypeptide; Gastrins; Gastrointestinal Diseases; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Insulin Secretion; Intestinal Absorption; Peptide Fragments; Peptides | 1982 |
Gut glucagon-like immunoreactants.
Topics: Antigens; Chemical Phenomena; Chemistry; Diabetes Mellitus; Dumping Syndrome; Gastrectomy; Gastrointestinal Hormones; Glucagon-Like Peptides; Humans; Intestine, Small; Obesity; Pancreatitis; Peptides; Radioimmunoassay; Vagotomy | 1980 |
[Diet therapy: role of incretin and dietary fibers].
Topics: Diabetes Mellitus; Diet Therapy; Dietary Fiber; Dietetics; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Peptide Fragments | 1995 |
[Incretin research in the development of new strategies of diabetes therapy].
Topics: Amino Acid Sequence; Blood Glucose; Diabetes Mellitus; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Molecular Sequence Data; Peptide Fragments; Peptides; Protein Precursors; Receptors, Glucagon | 1995 |
Glucagon-like peptide-I and the control of insulin secretion in the normal state and in NIDDM.
Topics: Animals; Cloning, Molecular; Diabetes Mellitus, Type 2; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Peptide Fragments; Peptides; Protein Precursors; Signal Transduction | 1993 |
Glucagon and its family revisited.
Topics: Amino Acid Sequence; Animals; Diabetes Mellitus; Gene Expression Regulation; Glicentin; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Homeostasis; Humans; Hypoglycemia; Islets of Langerhans; Molecular Sequence Data; Peptide Fragments; Protein Precursors | 1995 |
Central glucagon-like peptide-I in the control of feeding.
Topics: Animals; Brain; Feeding Behavior; Genes, fos; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Humans; Hyperglycemia; Hyperinsulinism; Neurons; Peptide Fragments; Protein Precursors; Rats; Rats, Zucker; Receptors, Glucagon; Venoms | 1996 |
Nutrient-induced secretion and metabolic effects of glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1.
Topics: Adaptation, Physiological; Adipose Tissue; Animals; Coronary Disease; Diabetes Mellitus, Type 2; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Obesity; Peptide Fragments | 1996 |
Therapeutic potential of glucagon-like peptide 1 in type 2 diabetes.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 2; Gastric Emptying; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Hypoglycemic Agents; Infusions, Intravenous; Injections, Subcutaneous; Peptide Fragments; Postprandial Period; Protein Precursors | 1996 |
Endoprotease regulation of miniglucagon production.
Topics: Amino Acid Sequence; Animals; Endopeptidases; Female; Gastric Mucosa; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Intestine, Small; Islets of Langerhans; Male; Molecular Sequence Data; Muscle, Smooth; Organ Specificity; Peptide Biosynthesis; Peptide Fragments; Peptides; Protein Precursors; Protein Processing, Post-Translational | 1996 |
Synthesis and biochemical characterization of proglucagon-related peptides.
Topics: Amino Acid Sequence; Animals; Glicentin; Glucagon; Glucagon-Like Peptides; Glucose; Humans; Immunoradiometric Assay; Insulin; Insulin Secretion; Islets of Langerhans; Molecular Sequence Data; Peptide Fragments; Proglucagon; Protein Precursors; Radioimmunoassay; Rats; Recombinant Fusion Proteins; Recombinant Proteins | 1996 |
Enteroglucagon.
Topics: Animals; Glicentin; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Humans; Intestinal Mucosa; Oxyntomodulin; Peptide Fragments; Peptides; Proglucagon; Protein Precursors | 1997 |
Epithelial cell growth and differentiation. I. Intestinal growth factors.
Topics: Animals; Cell Differentiation; Cell Division; Gastrointestinal Hormones; Glucagon-Like Peptides; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Intestinal Mucosa; Intestine, Large; Intestine, Small; Peptides | 1997 |
[Glucagon, GLP].
Topics: Animals; Base Sequence; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Humans; Molecular Sequence Data; Peptides; Protein Precursors; Receptors, Glucagon; Sequence Homology, Nucleic Acid | 1997 |
Control of appetite--the role of glucagon-like peptide-1 (7-36) amide.
Topics: Adipocytes; Animals; Appetite Regulation; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Neurotransmitter Agents; Obesity; Peptide Fragments | 1997 |
Cellular regulation of islet hormone secretion by the incretin hormone glucagon-like peptide 1.
Topics: Animals; Calcium; Diabetes Mellitus, Type 2; Exocytosis; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Humans; Ion Channels; Islets of Langerhans; Pancreatic Hormones; Peptide Fragments; Protein Precursors; Receptors, Glucagon | 1998 |
Biological actions of glucagon-like peptide(GLP)-2 revealed--how pluripotential is the glucagon gene?
Topics: Cell Division; Glucagon; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Humans; Peptides | 1998 |
Surgical aspect of enteroinsular axis after gastrointestinal surgery with reference to incretin secretion.
Topics: Digestive System Surgical Procedures; Dumping Syndrome; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Neurotransmitter Agents; Pancreas; Peptide Fragments; Postoperative Complications | 1998 |
[GLP-1 (7-36) amide [GLIP-glucagon like insulinotropic peptide] as a potential treatment for NIDDM].
Topics: Animals; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Peptide Fragments | 1998 |
Stimulatory transducing systems in pancreatic islet cells.
Topics: Animals; Cytoplasmic Granules; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; GTP-Binding Proteins; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Peptide Fragments; Peptides; Receptors, Glucagon; Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide; Receptors, Pituitary Hormone; Receptors, Vasoactive Intestinal Peptide; Rodentia; Signal Transduction | 1998 |
Glucagon-like peptide-1 (7-36) amide as a novel neuropeptide.
Topics: Animals; Brain; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Neuropeptides; Neurotransmitter Agents; Peptide Fragments; Rats; Receptors, Glucagon | 1998 |
Is glucagon-like peptide 1 an incretin hormone?
Topics: Animals; Diabetes Mellitus, Type 2; Digestion; Gastric Emptying; Gastrointestinal Hormones; Gastrointestinal Motility; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Insulin Secretion; Peptide Fragments; Protein Precursors | 1999 |
Ileal [correction of ilial] transposition and enteroglucagon/GLP-1 in obesity (and diabetic?) surgery.
Topics: Animals; Biliopancreatic Diversion; Diabetes Mellitus, Type 2; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Ileum; Obesity, Morbid; Peptide Fragments; Protein Precursors; Rats | 1999 |
The glucagon-like peptides.
Topics: Amino Acid Sequence; Animals; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Molecular Sequence Data; Peptide Fragments; Peptides; Protein Precursors | 1999 |
[Hepatogenic diabetes--the current concepts of its pathophysiology and therapy].
Topics: Diabetes Mellitus; Diabetes Mellitus, Type 2; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Humans; Hypoglycemic Agents; Insulin Resistance; Liver; Liver Diseases; Peptide Fragments; Receptor, Insulin | 1999 |
Glucagon-like peptide-1 (7-36) amide: a central regulator of satiety and interoceptive stress.
Topics: Animals; Eating; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Neurotransmitter Agents; Peptide Fragments; Satiety Response; Stress, Psychological | 1999 |
Stem cells: the intestinal stem cell as a paradigm.
Topics: Adenomatous Polyposis Coli; Animals; Cell Differentiation; Cell Division; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cyclooxygenase 2; Glucagon-Like Peptides; Humans; Intestinal Mucosa; Intestines; Isoenzymes; Membrane Proteins; Neoplasms; Peptides; Prostaglandin-Endoperoxide Synthases; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Stem Cells; Transforming Growth Factor beta; Tumor Suppressor Protein p53 | 2000 |
Kinetic analysis of enzymatic and nonenzymatic degradation of peptides by MALDI-TOFMS.
Topics: Animals; Dipeptidyl Peptidase 4; Flavobacterium; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Kinetics; Peptide Fragments; Peptides; Prolyl Oligopeptidases; Serine Endopeptidases; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2000 |
Effects of fructans-type prebiotics on lipid metabolism.
Topics: Animals; Blood Glucose; Fatty Acids; Fructans; Gene Expression Regulation, Enzymologic; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Hypolipidemic Agents; Insulin; Lipid Metabolism; Lipoproteins; Liver; Neurotransmitter Agents; Oligosaccharides; Peptide Fragments; Rats; Triglycerides | 2001 |
The entero-insular axis in type 2 diabetes--incretins as therapeutic agents.
Topics: Animals; Diabetes Mellitus, Type 2; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Intestines; Islets of Langerhans; Peptide Fragments; Protein Precursors | 2001 |
Control of glucose homeostasis by incretin hormones.
Topics: Animals; Blood Glucose; Energy Metabolism; Gastrointestinal Hormones; Gastrointestinal Motility; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Gluconeogenesis; Glucose; Homeostasis; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Liver; Peptide Fragments | 1999 |
A meta-analysis of the effect of glucagon-like peptide-1 (7-36) amide on ad libitum energy intake in humans.
Topics: Adult; Appetite; Cross-Over Studies; Dose-Response Relationship, Drug; Eating; Energy Metabolism; Gastric Emptying; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Hunger; Infusions, Intravenous; Injections, Intravenous; Male; Obesity; Peptide Fragments; Randomized Controlled Trials as Topic; Satiety Response | 2001 |
Incretin hormones--an update.
Topics: Animals; Diabetes Mellitus, Type 2; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Humans; Insulin; Insulin Secretion; Intestinal Mucosa; Peptide Fragments; Protein Precursors | 2001 |
Endocrine and neuroendocrine signals of energy stores: view from the chair.
Topics: Brain; Cytokines; Eating; Endocrine Glands; Energy Metabolism; Feedback; Glucagon-Like Peptides; Humans; Insulin; Intestines; Leptin; Neurosecretory Systems; Peptides; Signal Transduction | 2001 |
Glucose tolerance, glucose utilization and insulin secretion in ageing.
Topics: Aging; Diabetes Mellitus, Type 2; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glucose Tolerance Test; Humans; Insulin; Islets of Langerhans; Liver; Peptide Fragments | 2002 |
New therapeutic developments in the regulation of food intake by neuropeptides.
Topics: Animals; Energy Intake; Glucagon-Like Peptides; Humans; Nerve Tissue Proteins; Peptides | 2002 |
Gastric inhibitory polypeptide analogues: do they have a therapeutic role in diabetes mellitus similar to that of glucagon-like Peptide-1?
Topics: Animals; Diabetes Mellitus, Type 2; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Insulin Secretion; Peptide Fragments; Protein Precursors | 2002 |
[Review: regulation of glucose metabolism].
Topics: Animals; Blood Glucose; Diabetes Mellitus; Fasting; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucokinase; Glucose; Glucose Transporter Type 2; Glycogen; Humans; Insulin; Insulin Secretion; Intestinal Absorption; Liver; Monosaccharide Transport Proteins; Peptide Fragments; Protein Precursors | 2002 |
[Glucagon and GLP (glucagon-like peptide)].
Topics: Animals; Diabetes Mellitus; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Hyperglycemia; Peptide Fragments; Peptides; Protein Precursors | 2002 |
[Glucagon-like peptide-1 (GLP-1) receptor].
Topics: Animals; Diabetes Mellitus, Type 2; Exenatide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Humans; Insulin; Insulin Secretion; Peptide Fragments; Peptides; Polymorphism, Genetic; Protein Precursors; Receptors, Glucagon; Venoms | 2002 |
[Regulation of insulin secretion by incretins].
Topics: Animals; Carrier Proteins; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Guanine Nucleotide Exchange Factors; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Nuclear Proteins; Peptide Fragments | 2002 |
Aging and insulin secretion.
Topics: Adult; Aged; Aged, 80 and over; Aging; Diabetes Mellitus, Type 2; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Intolerance; Humans; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Middle Aged; Nutrition Surveys; Peptide Fragments | 2003 |
Anorectic brainstem peptides: more pieces to the puzzle.
Topics: Animals; Anorexia; Brain Stem; Eating; Glucagon-Like Peptides; Homeostasis; Hypothalamic Hormones; Neuropeptides; Peptides; Prolactin-Releasing Hormone; Solitary Nucleus | 2003 |
Glucagon-like peptide 1 and gastric inhibitory polypeptide: potential applications in type 2 diabetes mellitus.
Topics: Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Exenatide; Gastric Inhibitory Polypeptide; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Hypoglycemic Agents; Peptide Fragments; Peptides; Protease Inhibitors; Protein Precursors; Venoms | 2003 |
Neutral endopeptidase 24.11 and dipeptidyl peptidase IV are both involved in regulating the metabolic stability of glucagon-like peptide-1 in vivo.
Topics: Amino Acid Sequence; Animals; Dipeptidyl Peptidase 4; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Insulin Secretion; Kinetics; Mice; Molecular Sequence Data; Neprilysin; Peptide Fragments; Protease Inhibitors; Protein Precursors | 2003 |
[Current topics in endocrinology: incretin].
Topics: Animals; Cytokines; Diabetes Mellitus; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Peptide Fragments | 2003 |
Central pre-proglucagon derived peptides: opportunities for treatment of obesity.
Topics: Animals; Behavior, Animal; Central Nervous System; Eating; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Humans; Obesity; Oxyntomodulin; Peptide Fragments; Peptides; Proglucagon; Protein Precursors; Receptors, Glucagon | 2003 |
Adaptation following intestinal resection: mechanisms and signals.
Topics: Animals; Biomarkers; Disease Models, Animal; Epidermal Growth Factor; Glucagon-Like Peptides; Glucocorticoids; Glutamine; Growth Hormone; Humans; Insulin-Like Growth Factor I; Intestinal Absorption; Intestinal Mucosa; Intestines; Peptides; Short Bowel Syndrome | 2003 |
Glucagon-like peptide 2 (GLP-2), an intestinotrophic mediator.
Topics: Amino Acid Sequence; Animals; Gastrointestinal Hormones; Glicentin; Glucagon; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Humans; Intestines; Molecular Sequence Data; Peptide Fragments; Peptides; Protein Precursors; Rats; Receptors, Glucagon | 2004 |
Gastrointestinal satiety signals III. Glucagon-like peptide 1, oxyntomodulin, peptide YY, and pancreatic polypeptide.
Topics: Digestive System; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Oxyntomodulin; Pancreatic Polypeptide; Peptide Fragments; Peptide YY; Protein Precursors; Satiety Response; Signal Transduction | 2004 |
[Glucagon 2004: homage to Roger Assan].
Topics: Glicentin; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; History, 20th Century; Humans; Peptide Fragments; Peptides; Protein Precursors | 2004 |
Gut hormones and the control of appetite.
Topics: Animals; Appetite Regulation; Cholecystokinin; Gastrointestinal Hormones; Ghrelin; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Leptin; Obesity; Oxyntomodulin; Pancreatic Polypeptide; Peptide Fragments; Peptide Hormones; Peptide YY; Protein Precursors | 2004 |
[Oral diabetes treatment. Which substance is indicated at which time?].
Topics: Administration, Oral; Diabetes Mellitus, Type 2; Germany; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Hypoglycemic Agents; Metformin; Obesity; Peptide Fragments; Peptides; Practice Guidelines as Topic; Practice Patterns, Physicians'; Treatment Outcome | 2004 |
Gut hormones as peripheral anti obesity targets.
Topics: Animals; Anti-Obesity Agents; Appetite Regulation; Drug Design; Gastrointestinal Hormones; Ghrelin; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Mice; Obesity; Oxyntomodulin; Pancreatic Polypeptide; Peptide Fragments; Peptide Hormones; Peptide YY; Protein Precursors; Rats; Receptors, G-Protein-Coupled | 2004 |
[Pancreatic glucagon (IRG), enteroglucagon (EG)].
Topics: Biomarkers; Diabetes Mellitus; Diagnostic Techniques, Endocrine; Dumping Syndrome; Glucagon; Glucagon-Like Peptides; Glucagonoma; Humans; Liver Diseases; Pancreatic Diseases; Pancreatic Neoplasms; Radioimmunoassay; Reference Values; Specimen Handling | 2005 |
Proglucagon-derived peptides: mechanisms of action and therapeutic potential.
Topics: Animals; Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Disease; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Humans; Intestinal Diseases; Peptide Fragments; Peptides; Proglucagon; Protease Inhibitors; Protein Precursors; Receptors, Glucagon | 2005 |
Applications of dipeptidyl peptidase IV inhibitors in diabetes mellitus.
Topics: Amino Acid Sequence; Animals; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glucose Tolerance Test; Humans; Molecular Sequence Data; Peptide Fragments; Protease Inhibitors | 2006 |
Glucagon and glucagon-like peptide receptors as drug targets.
Topics: Amino Acid Sequence; Animals; Diabetes Mellitus; Glucagon; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Humans; Hypoglycemic Agents; Molecular Sequence Data; Oxyntomodulin; Receptors, Glucagon | 2006 |
Major contributions of comparative endocrinology to the development and exploitation of the incretin concept.
Topics: Amino Acid Sequence; Animals; Anura; Exenatide; Fishes; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Humans; Hypoglycemic Agents; Intestinal Mucosa; Molecular Sequence Data; Peptide Fragments; Peptides; Sequence Alignment; Venoms | 2006 |
Biologic actions and therapeutic potential of the proglucagon-derived peptides.
Topics: Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Humans; Intestinal Mucosa; Proglucagon | 2005 |
Glucagon and glucagon-like peptides 1 and 2.
Topics: Animals; Brain Stem; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Humans; Models, Biological; Neurons; Peptide Fragments; Peptides; Proprotein Convertase 1; Proprotein Convertase 2; Protein Processing, Post-Translational | 2010 |
The mechanism of action for oxyntomodulin in the regulation of obesity.
Topics: Animals; Appetite Depressants; Appetite Regulation; Clinical Trials as Topic; Drug Evaluation, Preclinical; Eating; Energy Metabolism; Enteroendocrine Cells; Gastrointestinal Tract; Glucagon; Glucagon-Like Peptides; Humans; Obesity; Oxyntomodulin | 2010 |
Incretin hormones and the expanding families of glucagon-like sequences and their receptors.
Topics: Animals; Base Sequence; Chickens; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptides; Humans; Incretins; Mammals; Phylogeny; Protein Precursors; Receptors, Glucagon; Xenopus | 2011 |
The forgotten members of the glucagon family.
Topics: Animals; Energy Metabolism; Glicentin; Glucagon; Humans; Multigene Family; Oxyntomodulin; Peptide Fragments | 2014 |
Therapeutic potential of coagonists of glucagon and GLP-1.
Topics: Animals; Cardiovascular Diseases; Glucagon; Glucagon-Like Peptide 1; Humans; Oxyntomodulin | 2014 |
Do glucagonomas always produce glucagon?
Topics: Animals; Gastrointestinal Diseases; Gene Expression Regulation; Glicentin; Glucagon; Glucagon-Like Peptide 1; Glucagon-Secreting Cells; Glucagonoma; Humans; Hypoglycemia; Islets of Langerhans; Oxyntomodulin; Pancreas; Pancreatic Neoplasms; Peptide Fragments; Peptides; Phenotype; Proglucagon; Protein Domains | 2016 |
Glucagon-related peptides and the regulation of food intake in chickens.
Topics: Animals; Brain; Chickens; Eating; Energy Metabolism; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucose; Homeostasis; Intestinal Mucosa; Neurotransmitter Agents; Organ Specificity; Oxyntomodulin; Pancreas | 2016 |
The biology of glucagon and the consequences of hyperglucagonemia.
Topics: Diabetes Mellitus; Glucagon; Glucagon-Like Peptide 1; Glucagonoma; Humans; Liver; Neoplasms; Non-alcoholic Fatty Liver Disease; Oxyntomodulin; Pancreas; Receptors, Glucagon | 2016 |
Physiological and pathophysiological aspects of incretin hormones and glucagon.
Topics: Animals; Appetite; Diabetes Mellitus, Type 2; Enteroendocrine Cells; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Humans; Incretins; Insulin; Oxyntomodulin; Peptide Fragments | 2017 |
On the role of the gut in diabetic hyperglucagonaemia.
Topics: Blood Glucose; Diabetes Mellitus, Type 2; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptides; Glucagon-Secreting Cells; Humans; Hyperglycemia; Insulin | 2017 |
Oxyntomodulin: Actions and role in diabetes.
Topics: Amino Acids; Diabetes Mellitus; Glucagon; Humans; Obesity; Oxyntomodulin; Proglucagon; Proprotein Convertases | 2018 |
Clinical implications of current cardiovascular outcome trials with sodium glucose cotransporter-2 (SGLT2) inhibitors.
Topics: Albuminuria; Atherosclerosis; Benzhydryl Compounds; Body Weight; Canagliflozin; Cardiovascular Diseases; Cardiovascular System; Glucagon; Glucagon-Like Peptides; Glucosides; Heart Failure; Hemodynamics; Humans; Hypoglycemic Agents; Ketones; Lipids; Liraglutide; Metabolic Syndrome; Metformin; Non-alcoholic Fatty Liver Disease; Osmosis; Risk Factors; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Treatment Outcome | 2018 |
[Technological Innovations in Diabetes Therapy].
Topics: Administration, Oral; Blood Glucose Self-Monitoring; Clinical Trials, Phase III as Topic; Diabetes Mellitus; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Insulin Infusion Systems; Inventions; Pancreas, Artificial | 2018 |
Peptides in the regulation of glucagon secretion.
Topics: Animals; Blood Glucose; Calcitonin; Gastric Inhibitory Polypeptide; Ghrelin; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Humans; Insulin; Islet Amyloid Polypeptide; Neurotensin; Oxyntomodulin; Oxytocin; Pancreas; Pancreatic Polypeptide; Somatostatin; Urocortins; Vasopressins | 2022 |
The Molecular Determinants of Glucagon-like Peptide Secretion by the Intestinal L cell.
Topics: Diabetes Mellitus, Type 2; Enteroendocrine Cells; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Humans; Peptide Fragments; Peptides; Secretagogues | 2022 |
Emerging roles of oxyntomodulin-based glucagon-like peptide-1/glucagon co-agonist analogs in diabetes and obesity.
Topics: Diabetes Mellitus, Type 2; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Humans; Obesity; Oxyntomodulin | 2023 |
62 trial(s) available for glucagon and oxyntomodulin
| Article | Year |
|---|---|
Effect of motilin on the rate of gastric emptying and gut hormone release during breakfast.
Topics: Adult; Blood Glucose; Clinical Trials as Topic; Double-Blind Method; Eating; Gastric Emptying; Gastric Inhibitory Polypeptide; Gastrins; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Humans; Insulin; Insulin Secretion; Male; Motilin; Pancreatic Polypeptide; Sodium Chloride; Vasoactive Intestinal Peptide | 1979 |
Lack of effect of synthetic human gastric inhibitory polypeptide and glucagon-like peptide 1 [7-36 amide] infused at near-physiological concentrations on pentagastrin-stimulated gastric acid secretion in normal human subjects.
Topics: Adult; Blood Glucose; Gastric Acid; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Hormones; Humans; Infusions, Intravenous; Male; Pentagastrin; Peptide Fragments; Stimulation, Chemical | 1992 |
Insulinotropic action of glucagonlike peptide-I-(7-37) in diabetic and nondiabetic subjects.
Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 2; Eating; Fasting; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Kinetics; Male; Middle Aged; Peptide Fragments; Peptides; Reference Values; Time Factors | 1992 |
Enteroglucagon release in disaccharide malabsorption induced by intestinal alpha-glucosidase inhibition.
Topics: Acarbose; Adult; Blood Glucose; Disaccharides; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Glucose; Glycoside Hydrolase Inhibitors; Humans; Insulin; Intestinal Absorption; Intestines; Male; Maltose; Motilin; Sucrose; Trisaccharides | 1989 |
Oxyntomodulin: a potential hormone from the distal gut. Pharmacokinetics and effects on gastric acid and insulin secretion in man.
Topics: Gastric Acid; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Humans; Insulin; Insulin Secretion; Oxyntomodulin; Pentagastrin; Radioimmunoassay | 1988 |
The effect of pirenzepine on meal-stimulated gastrointestinal hormones.
Topics: Adult; Benzodiazepinones; Eating; Gastric Inhibitory Polypeptide; Gastrins; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Humans; Insulin; Neurotensin; Pancreatic Polypeptide; Piperazines; Pirenzepine; Somatostatin; Vasoactive Intestinal Peptide | 1980 |
Gut and pancreatic hormones after jejunoileal bypass with 3:1 or 1:3 jejunoileal ratio.
Topics: Adult; Female; Gastric Inhibitory Polypeptide; Gastrins; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Humans; Ileum; Insulin; Jejunum; Male; Middle Aged; Obesity; Pancreatic Hormones; Pancreatic Polypeptide | 1983 |
Pharmacokinetic, insulinotropic, and glucagonostatic properties of GLP-1 [7-36 amide] after subcutaneous injection in healthy volunteers. Dose-response-relationships.
Topics: Adult; Analysis of Variance; Blood Glucose; Body Mass Index; C-Peptide; Dose-Response Relationship, Drug; Fasting; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Injections, Subcutaneous; Insulin; Kinetics; Male; Peptide Fragments; Random Allocation; Reference Values; Time Factors | 1995 |
Physiological augmentation of amino acid-induced insulin secretion by GIP and GLP-I but not by CCK-8.
Topics: Adult; Amino Acids; Dietary Proteins; Eating; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Insulin Secretion; Male; Pancreas; Peptide Fragments; Peptides; Sincalide | 1995 |
Glucagon-like peptide-1 7-36 amide and peptide YY from the L-cell of the ileal mucosa are potent inhibitors of vagally induced gastric acid secretion in man.
Topics: Adult; Animals; Depression, Chemical; Female; Gastric Acid; Gastrins; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Ileum; Intestinal Mucosa; L Cells; Male; Mice; Middle Aged; Peptide Fragments; Peptide YY; Peptides; Somatostatin; Vagus Nerve | 1994 |
Endocrine cells in colorectal adenocarcinomas: incidence, hormone profile and prognostic relevance.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Chromogranin A; Chromogranins; Colonic Neoplasms; Cytoplasm; Endocrine Glands; Female; Follow-Up Studies; Glicentin; Glucagon; Glucagon-Like Peptides; Humans; Male; Middle Aged; Neoplasm Staging; Peptide Fragments; Prognosis; Prospective Studies; Protein Precursors; Rectal Neoplasms; Serotonin; Somatostatin; Survival Analysis | 1993 |
Normalization of fasting hyperglycaemia by exogenous glucagon-like peptide 1 (7-36 amide) in type 2 (non-insulin-dependent) diabetic patients.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 2; Fasting; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glycated Hemoglobin; Humans; Hyperglycemia; Hypoglycemic Agents; Infusions, Intravenous; Kinetics; Male; Middle Aged; Peptide Fragments; Time Factors | 1993 |
Preserved incretin activity of glucagon-like peptide 1 [7-36 amide] but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus.
Topics: Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Clamp Technique; Glycated Hemoglobin; Humans; Insulin; Insulin Secretion; Kinetics; Male; Middle Aged; Peptide Fragments; Protein Precursors; Reference Values; Time Factors | 1993 |
Additive insulinotropic effects of exogenous synthetic human gastric inhibitory polypeptide and glucagon-like peptide-1-(7-36) amide infused at near-physiological insulinotropic hormone and glucose concentrations.
Topics: Administration, Oral; Adult; Blood Glucose; Drug Combinations; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Humans; Infusions, Intravenous; Insulin; Male; Osmolar Concentration; Pancreas; Peptide Fragments | 1993 |
Glucagonostatic actions and reduction of fasting hyperglycemia by exogenous glucagon-like peptide I(7-36) amide in type I diabetic patients.
Topics: Adult; Analysis of Variance; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Fasting; Fatty Acids, Nonesterified; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Male; Peptide Fragments; Protein Precursors; Time Factors | 1996 |
Potential therapeutic levels of glucagon-like peptide I achieved in humans by a buccal tablet.
Topics: Absorption; Adult; Blood Glucose; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Half-Life; Humans; Insulin; Middle Aged; Peptide Fragments; Radioimmunoassay; Tablets | 1996 |
Glucagon-like peptide I enhances the insulinotropic effect of glibenclamide in NIDDM patients and in the perfused rat pancreas.
Topics: Analysis of Variance; Animals; Diabetes Mellitus, Type 2; Drug Synergism; Drug Therapy, Combination; Gastric Emptying; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glyburide; Humans; In Vitro Techniques; Infusions, Intravenous; Insulin; Insulin Secretion; Islets of Langerhans; Middle Aged; Peptide Fragments; Perfusion; Protein Precursors; Rats; Rats, Sprague-Dawley; Treatment Failure | 1996 |
GLP-1 does not not acutely affect insulin sensitivity in healthy man.
Topics: 3-Hydroxybutyric Acid; Adult; Alanine; Analysis of Variance; Blood Glucose; C-Peptide; Calorimetry, Indirect; Fatty Acids, Nonesterified; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Clamp Technique; Humans; Hydroxybutyrates; Infusions, Intravenous; Insulin; Insulin Secretion; Lactates; Male; Neurotransmitter Agents; Peptide Fragments; Reference Values; Somatostatin; Time Factors | 1996 |
Effects of subcutaneous glucagon-like peptide 1 (GLP-1 [7-36 amide]) in patients with NIDDM.
Topics: Adult; Aged; Blood Glucose; C-Peptide; Cohort Studies; Diabetes Mellitus, Type 2; Fasting; Female; Gastric Emptying; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Injections, Subcutaneous; Insulin; Male; Middle Aged; Peptide Fragments; Peptides | 1996 |
Effects of glucagon-like peptide 1 (7-36 amide) on whole-body protein metabolism in healthy man.
Topics: Adult; Blood Glucose; C-Peptide; Calorimetry, Indirect; Energy Metabolism; Fatty Acids, Nonesterified; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Clamp Technique; Glycerol; Humans; Insulin; Leucine; Male; Pancreas; Peptide Fragments; Peptides; Proteins | 1997 |
Subcutaneous glucagon-like peptide I combined with insulin normalizes postcibal glycemic excursions in IDDM.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Drug Therapy, Combination; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Hypoglycemic Agents; Injections, Subcutaneous; Insulin; Male; Middle Aged; Pancreatic Polypeptide; Peptide Fragments; Time Factors | 1997 |
Acute incretin response to oral glucose is associated with stimulation of gastric inhibitory polypeptide, not glucagon-like peptide in young subjects.
Topics: Administration, Oral; Adolescent; Adult; C-Peptide; Gastric Inhibitory Polypeptide; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glucose Clamp Technique; Humans; Hyperglycemia; Peptide Fragments; Peptides; Secretory Rate; Stimulation, Chemical | 1997 |
Glucagon-like peptide-1 7-36 amide and peptide YY have additive inhibitory effect on gastric acid secretion in man.
Topics: Adult; Drug Interactions; Female; Gastric Acid; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Infusions, Intravenous; Male; Middle Aged; Neurotransmitter Agents; Pentagastrin; Peptide Fragments; Peptide YY; Peptides | 1997 |
Acetylation of or beta-cyclodextrin addition to potato beneficial effect on glucose metabolism and appetite sensations.
Topics: Acetylation; Adult; Anthropometry; Appetite Depressants; beta-Cyclodextrins; Blood Glucose; Cyclodextrins; Dietary Carbohydrates; Energy Metabolism; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptides; Heart Rate; Humans; Insulin; Lactates; Male; Oxidation-Reduction; Peptides; Solanum tuberosum; Triglycerides | 1997 |
Glucagon-like peptide 1 inhibition of gastric emptying outweighs its insulinotropic effects in healthy humans.
Topics: Adult; Blood Glucose; C-Peptide; Eating; Fasting; Gastric Emptying; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Infusions, Intravenous; Insulin; Insulin Secretion; Peptide Fragments; Peptides; Postprandial Period; Protein Precursors; Reference Values; Time Factors | 1997 |
Mechanisms of the antidiabetic action of subcutaneous glucagon-like peptide-1(7-36)amide in non-insulin dependent diabetes mellitus.
Topics: Aged; Blood Glucose; Breath Tests; Diabetes Mellitus, Type 2; Female; Gastric Emptying; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Tolerance Test; Humans; Injections, Subcutaneous; Insulin; Male; Middle Aged; Neurotransmitter Agents; Pancreatic Polypeptide; Peptide Fragments; Postprandial Period; Regression Analysis | 1998 |
Prolonged and enhanced secretion of glucagon-like peptide 1 (7-36 amide) after oral sucrose due to alpha-glucosidase inhibition (acarbose) in Type 2 diabetic patients.
Topics: Acarbose; Administration, Oral; Aged; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Female; Gastric Inhibitory Polypeptide; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Insulin; Male; Middle Aged; Peptide Fragments; Sucrose; Time Factors; Trisaccharides | 1998 |
Normalization of fasting glycaemia by intravenous GLP-1 ([7-36 amide] or [7-37]) in type 2 diabetic patients.
Topics: Age of Onset; Aged; Blood Glucose; C-Peptide; Calorimetry, Indirect; Cholesterol; Diabetes Mellitus, Type 2; Fasting; Fatty Acids, Nonesterified; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Infusions, Intravenous; Insulin; Insulin Secretion; Male; Middle Aged; Peptide Fragments; Peptides; Triglycerides | 1998 |
Subcutaneous glucagon-like peptide-1 (7-36) amide is insulinotropic and can cause hypoglycaemia in fasted healthy subjects.
Topics: Adult; Blood Glucose; Blood Pressure; Cross-Over Studies; Double-Blind Method; Fasting; Female; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Male; Peptide Fragments; Pulse | 1998 |
Differential effects of saturated and monounsaturated fatty acids on postprandial lipemia and incretin responses in healthy subjects.
Topics: Adult; Blood Glucose; Butter; Cholesterol, HDL; Diet; Dietary Fats; Fatty Acids; Fatty Acids, Monounsaturated; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Male; Neurotransmitter Agents; Olive Oil; Peptide Fragments; Peptides; Plant Oils; Postprandial Period; Triglycerides | 1999 |
Octreotide suppresses the incretin glucagon-like peptide (7-36) amide in patients with acromegaly or clinically nonfunctioning pituitary tumors and in healthy subjects.
Topics: Acromegaly; Adenoma; Adult; Antineoplastic Agents, Hormonal; Blood Glucose; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Tolerance Test; Hormones; Human Growth Hormone; Humans; Insulin; Male; Middle Aged; Octreotide; Peptide Fragments; Pituitary Neoplasms; Prospective Studies; Protein Precursors | 1999 |
Continuous subcutaneous infusion of glucagon-like peptide 1 lowers plasma glucose and reduces appetite in type 2 diabetic patients.
Topics: Adult; Aged; Appetite; Appetite Depressants; Blood Glucose; Blood Pressure; C-Peptide; Diabetes Mellitus, Type 2; Drug Delivery Systems; Energy Intake; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Hypoglycemic Agents; Infusion Pumps; Insulin; Lipids; Middle Aged; Peptide Fragments; Peptides; Pilot Projects; Postprandial Period; Protein Precursors | 1999 |
Effect of glucagon-like peptide 1(7-36)amide in insulin-treated patients with diabetes mellitus secondary to chronic pancreatitis.
Topics: Aged; Blood Glucose; C-Peptide; Chronic Disease; Diabetes Mellitus; Drug Therapy, Combination; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glycated Hemoglobin; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Middle Aged; Pancreatitis; Peptide Fragments | 2000 |
A novel hyperglycaemic clamp for characterization of islet function in humans: assessment of three different secretagogues, maximal insulin response and reproducibility.
Topics: Adult; Arginine; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glucose Clamp Technique; Humans; Hyperglycemia; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Male; Peptide Fragments; Protein Precursors; Reproducibility of Results | 2000 |
Effect of glucagon-like peptide 1(7-36) amide on glucose effectiveness and insulin action in people with type 2 diabetes.
Topics: Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Food; Gastric Emptying; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Human Growth Hormone; Humans; Hydrocortisone; Insulin; Kinetics; Peptide Fragments; Somatostatin | 2000 |
Effect of nutrient ingestion on glucagon-like peptide 1 (7-36 amide) secretion in human type 1 and type 2 diabetes.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Eating; Female; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Male; Middle Aged; Peptide Fragments; Radioimmunoassay | 2000 |
Circulating levels of incretin hormones and amylin in the fasting state and after oral glucose in GH-deficient patients before and after GH replacement: a placebo-controlled study.
Topics: Adult; Amyloid; Fasting; Female; Gastric Inhibitory Polypeptide; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glucose Tolerance Test; Growth Hormone; Hormone Replacement Therapy; Human Growth Hormone; Humans; Islet Amyloid Polypeptide; Male; Peptide Fragments; Protein Precursors | 2000 |
Effect of metformin on glucagon-like peptide 1 (GLP-1) and leptin levels in obese nondiabetic subjects.
Topics: Adolescent; Adult; Blood Glucose; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Clamp Technique; Humans; Hypoglycemic Agents; Leptin; Male; Metformin; Middle Aged; Obesity; Peptide Fragments; Peptides | 2001 |
Additive glucose-lowering effects of glucagon-like peptide-1 and metformin in type 2 diabetes.
Topics: Blood Glucose; C-Peptide; Cross-Over Studies; Diabetes Mellitus, Type 2; Drug Administration Schedule; Drug Therapy, Combination; Female; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glycated Hemoglobin; Humans; Infusions, Parenteral; Insulin; Insulin Secretion; Kinetics; Male; Metformin; Middle Aged; Peptide Fragments; Placebos; Research Design | 2001 |
Impaired incretin response after a mixed meal is associated with insulin resistance in nondiabetic men.
Topics: Adult; Biomarkers; Blood Glucose; Blood Pressure; Body Weight; Eating; Gastric Inhibitory Polypeptide; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Clamp Technique; Humans; Insulin; Insulin Resistance; Male; Middle Aged; Peptide Fragments; Postprandial Period; Protein Precursors; Regression Analysis | 2001 |
Effect of glucagon-like peptide 1 on non-insulin-mediated glucose uptake in the elderly patient with diabetes.
Topics: Administration, Oral; Aged; Analysis of Variance; Blood Glucose; Diabetes Mellitus; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Clamp Technique; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Patient Selection; Peptide Fragments; Peptides | 2001 |
Glucagon-like peptide-1 (7-37) augments insulin-mediated glucose uptake in elderly patients with diabetes.
Topics: Aged; Biological Transport, Active; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glucose Clamp Technique; Humans; Insulin; Peptide Fragments; Peptides | 2001 |
Postprandial glucose, insulin, and incretin responses to grain products in healthy subjects.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Blood Glucose; Bread; Dietary Fiber; Fasting; Female; Gastric Emptying; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Male; Neurotransmitter Agents; Peptide Fragments; Postprandial Period; Secale; Triticum | 2002 |
Men at increased risk of coronary heart disease are not different from age- and weight-matched healthy controls in their postprandial triglyceride, nonesterified fatty acid, or incretin responses to sucrose.
Topics: Blood Glucose; Case-Control Studies; Coronary Disease; Fatty Acids, Nonesterified; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Male; Peptide Fragments; Postprandial Period; Risk Factors; Sucrose; Triglycerides | 2002 |
Effects of glucagon-like peptide-1(7-36)amide on motility and sensation of the proximal stomach in humans.
Topics: Adult; Blood Glucose; Gastric Emptying; Gastric Fundus; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Male; Muscle Relaxation; Peptide Fragments; Pressure; Satiety Response | 2002 |
Impaired beta-cell function, incretin effect, and glucagon suppression in patients with type 1 diabetes who have normal fasting glucose.
Topics: Arginine; Autoantibodies; Blood Glucose; Diabetes Mellitus, Type 1; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Clamp Technique; Glucose Tolerance Test; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Peptide Fragments; Reference Values | 2002 |
Effect of glucagon-like peptide 1 (7-36 amide) on insulin-mediated glucose uptake in patients with type 1 diabetes.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Clamp Technique; Humans; Hyperinsulinism; Insulin; Liver; Male; Neurotransmitter Agents; Peptide Fragments; Peptides | 2003 |
Effect of lipase inhibition on gastric emptying of, and the glycemic and incretin responses to, an oil/aqueous drink in type 2 diabetes mellitus.
Topics: Autonomic Nervous System; Blood Glucose; Diabetes Mellitus, Type 2; Dietary Fats; Enzyme Inhibitors; Female; Gastric Emptying; Gastric Inhibitory Polypeptide; Gastric Mucosa; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Hemodynamics; Humans; Insulin; Lactones; Lipase; Male; Middle Aged; Orlistat; Peptide Fragments; Peptides | 2003 |
The pathophysiology of diabetes involves a defective amplification of the late-phase insulin response to glucose by glucose-dependent insulinotropic polypeptide-regardless of etiology and phenotype.
Topics: Adult; Aged; Blood Glucose; C-Peptide; Chronic Disease; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; DNA-Binding Proteins; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Hepatocyte Nuclear Factor 1; Hepatocyte Nuclear Factor 1-alpha; Hepatocyte Nuclear Factor 1-beta; Humans; Hyperglycemia; Insulin; Islets of Langerhans; Male; Middle Aged; Neurotransmitter Agents; Nuclear Proteins; Pancreatitis; Peptide Fragments; Phenotype; Protein Precursors; Transcription Factors | 2003 |
Recombinant glucagon-like peptide-1 (7-36 amide) lowers fasting serum glucose in a broad spectrum of patients with type 2 diabetes.
Topics: Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Fasting; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Hypoglycemic Agents; Insulin; Metformin; Peptide Fragments; Placebos; Recombinant Proteins; Sulfonylurea Compounds | 2003 |
Ethanol with a mixed meal decreases the incretin levels early postprandially and increases postprandial lipemia in type 2 diabetic patients.
Topics: Aged; Alcohol Drinking; Butter; Cholesterol; Cholesterol, HDL; Chylomicrons; Diabetes Mellitus, Type 2; Dietary Carbohydrates; Dietary Fats; Energy Intake; Ethanol; Fatty Acids; Fatty Acids, Nonesterified; Food; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Lipids; Middle Aged; Peptide Fragments; Protein Precursors; Triglycerides | 2004 |
Blood glucose control in healthy subject and patients receiving intravenous glucose infusion or total parenteral nutrition using glucagon-like peptide 1.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Fatty Acids; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Humans; Hyperglycemia; Infusions, Intravenous; Insulin; Male; Middle Aged; Parenteral Nutrition, Total; Peptide Fragments; Placebos | 2004 |
Effects of glucagon-like peptide-1 in patients with acute myocardial infarction and left ventricular dysfunction after successful reperfusion.
Topics: Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Blood Glucose; Combined Modality Therapy; Diabetes Complications; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Male; Middle Aged; Myocardial Infarction; Peptide Fragments; Pilot Projects; Safety; Stroke Volume; Treatment Outcome; Ventricular Function, Left | 2004 |
[Glucagon 2004: homage to Roger Assan].
Topics: Glicentin; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; History, 20th Century; Humans; Peptide Fragments; Peptides; Protein Precursors | 2004 |
Peptide YY3-36 and glucagon-like peptide-17-36 inhibit food intake additively.
Topics: Animals; Behavior, Animal; Diabetes Mellitus; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Drug Synergism; Eating; Energy Intake; Feeding Behavior; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Immunohistochemistry; Injections, Intraperitoneal; Male; Mice; Mice, Inbred C57BL; Motor Activity; Obesity; Peptide Fragments; Peptide YY; Rats | 2005 |
Oxyntomodulin attenuates exendin-4-induced hypoglycemia in cattle.
Topics: Animals; Blood Glucose; Cattle; Cattle Diseases; Dose-Response Relationship, Drug; Exenatide; Glucagon; Glucagon-Like Peptide 1; Hypoglycemia; Insulin; Male; Oxyntomodulin; Peptides; Radioimmunoassay; Venoms | 2013 |
Effects of glucose-dependent insulinotropic polypeptide on gastric emptying, glycaemia and insulinaemia during critical illness: a prospective, double blind, randomised, crossover study.
Topics: Adult; Aged; Critical Illness; Cross-Over Studies; Double-Blind Method; Female; Gastric Emptying; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptides; Glucose; Humans; Hyperglycemia; Hypoglycemia; Infusions, Intravenous; Insulin; Male; Middle Aged; Prospective Studies | 2015 |
Effect of Oxyntomodulin, Glucagon, GLP-1, and Combined Glucagon +GLP-1 Infusion on Food Intake, Appetite, and Resting Energy Expenditure.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Appetite; Cross-Over Studies; Double-Blind Method; Drug Interactions; Eating; Energy Metabolism; Gastric Emptying; Glucagon; Glucagon-Like Peptide 1; Humans; Infusions, Intravenous; Male; Oxygen Consumption; Oxyntomodulin; Rest; Young Adult | 2015 |
Once-weekly dulaglutide 1.5 mg restores insulin secretion in response to intravenous glucose infusion.
Topics: Adult; Area Under Curve; Blood Glucose; C-Peptide; Cross-Over Studies; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Administration Schedule; Female; Glucagon; Glucagon-Like Peptides; Glucose; Humans; Hyperglycemia; Hypoglycemic Agents; Immunoglobulin Fc Fragments; Infusions, Intravenous; Injections, Subcutaneous; Insulin; Insulin-Secreting Cells; Male; Middle Aged; Recombinant Fusion Proteins; Treatment Outcome | 2017 |
Methods paper: Performance characteristics of novel assays for circulating levels of proglucagon-derived peptides and validation in a placebo controlled cross-over randomized clinical trial.
Topics: C-Peptide; Caffeine; Coffee; Glicentin; Glucagon; Glucagon-Like Peptide 1; Humans; Oxyntomodulin; Peptides; Proglucagon; Water | 2022 |
Effects of subcutaneous tirzepatide versus placebo or semaglutide on pancreatic islet function and insulin sensitivity in adults with type 2 diabetes: a multicentre, randomised, double-blind, parallel-arm, phase 1 clinical trial.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 2; Double-Blind Method; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin Resistance; Insulins; Islets of Langerhans; Treatment Outcome | 2022 |
Circulating levels of five proglucagon-derived peptides in response to intravenous or oral glucose or lipids and to a mixed-meal in subjects with normal weight, overweight, and obesity.
Topics: Glicentin; Glucagon; Glucagon-Like Peptide 1; Glucose; Humans; Lipids; Obesity; Overweight; Oxyntomodulin; Peptides; Proglucagon | 2022 |
644 other study(ies) available for glucagon and oxyntomodulin
| Article | Year |
|---|---|
Is GIP a glucagon cell constituent?
Topics: Animals; Cats; Dogs; Fluorescent Antibody Technique; Gastric Inhibitory Polypeptide; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Guinea Pigs; Haplorhini; Humans; Intestines; Pancreas; Pancreatic Neoplasms; Rats; Species Specificity; Swine | 1978 |
Fat-induced jejunal inhibition of gastric acid secretion and release of pancreatic glucagon, enteroglucagon, gastric inhibitory polypeptide, and vasoactive intestinal polypeptide in man.
Topics: Adult; Dietary Fats; Enteral Nutrition; Gastric Inhibitory Polypeptide; Gastric Juice; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Humans; Jejunum; Male; Secretory Rate; Vasoactive Intestinal Peptide | 1979 |
Distribution of the gut hormones in the primate intestinal tract.
Topics: Animals; Cholecystokinin; Digestive System; Gastric Inhibitory Polypeptide; Gastrins; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Haplorhini; Macaca; Motilin; Pancreatic Polypeptide; Papio; Secretin; Tissue Distribution; Vasoactive Intestinal Peptide | 1979 |
Hyperacidity and hypergastrinemia following extensive intestinal resection.
Topics: Animals; Dogs; Gastric Inhibitory Polypeptide; Gastric Juice; Gastrins; Glucagon; Glucagon-Like Peptides; Haplorhini; Humans; Insulin; Intestine, Small; Rats | 1979 |
Radioimmunoassay in diagnosis, localization and treatment of endocrine tumours in gut and pancreas.
Topics: Adenoma, Islet Cell; Carcinoid Tumor; Cholecystokinin; Gastric Inhibitory Polypeptide; Gastrins; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Humans; Insulin; Intestinal Neoplasms; Motilin; Pancreatic Hormones; Pancreatic Neoplasms; Pancreatic Polypeptide; Radioimmunoassay; Secretin; Somatostatin; Substance P; Vasoactive Intestinal Peptide; Zollinger-Ellison Syndrome | 1979 |
Gut glucagon-like immunoreactants (GLIs) and other enteric glucagon-like peptides.
Topics: Animals; Glucagon-Like Peptides; Humans; Peptides | 1978 |
Glicentin immunoreactive cells: their relationship to glucagon-producing cells.
Topics: Animals; Dogs; Fluorescent Antibody Technique; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Guinea Pigs; Intestinal Mucosa; Islets of Langerhans; Pancreas; Peptides; Rabbits; Rats; Species Specificity; Swine | 1979 |
Glucagon secretion in chronic pancreatitis.
Topics: Adult; Arginine; Chronic Disease; Female; Glucagon; Glucagon-Like Peptides; Glucose Tolerance Test; Humans; Infusions, Parenteral; Insulin; Islets of Langerhans; Male; Middle Aged; Pancreatitis | 1979 |
The enteroinsular axis.
Topics: Animals; Digestive System Physiological Phenomena; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Islets of Langerhans; Peptide Fragments; Peptides; Rats | 1978 |
The effect of feeds of differing composition on entero-insular hormone secretion in the first hours of life in human neonates.
Topics: Blood Glucose; Breast Feeding; Gastric Inhibitory Polypeptide; Gastrins; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Glucose; Humans; Infant Nutritional Physiological Phenomena; Infant, Newborn; Insulin; Milk, Human | 1979 |
Half life of gastrointestinal glucagon-like immunoreactive materials.
Topics: Animals; Antigens; Blood Glucose; Dogs; Gastric Mucosa; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Half-Life; Intestine, Small; Pancreas; Swine | 1979 |
How concentrate feeding affects glucoregulatory hormones in ruminants: implications in bovine ketosis.
Topics: Amino Acids; Animal Feed; Animals; Cattle; Fatty Acids, Volatile; Female; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Glucose; Ketosis; Lactation; Male; Pregnancy; Sheep | 1979 |
[Glucagon and lipid metabolism (author's transl)].
Topics: Animals; Carbohydrate Metabolism; Fatty Acids; Glucagon; Glucagon-Like Peptides; Humans; Insulin; Lipid Metabolism; Liver; Models, Biological | 1978 |
Metabolic and endocrine events at the time of the first feed of human milk in preterm and term infants.
Topics: Blood Glucose; Glucagon; Glucagon-Like Peptides; Growth Hormone; Hormones; Humans; Infant, Newborn; Infant, Premature; Insulin; Lactates; Milk, Human; Pyruvates | 1978 |
Lack of gastrointestinal glucagon response to hypoglycaemia in depancreatized dogs.
Topics: Animals; Arginine; Dogs; Glucagon; Glucagon-Like Peptides; Hypoglycemia; Pancreatectomy | 1978 |
Endocrine cells of the gastrointestinal tract and their pathology.
Topics: Animals; Carcinoid Tumor; Cholecystokinin; Dogs; Enterochromaffin Cells; Gastric Inhibitory Polypeptide; Gastric Mucosa; Gastrins; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Humans; Intestinal Mucosa; Intestinal Neoplasms; Pancreatic Polypeptide; Rats; Secretin; Somatostatin; Stomach Neoplasms; Vasoactive Intestinal Peptide | 1978 |
Insulinotropic hormone glucagon-like peptide-I(7-37) stimulation of proinsulin gene expression and proinsulin biosynthesis in insulinoma beta TC-1 cells.
Topics: Animals; Chloramphenicol O-Acetyltransferase; Cyclic AMP; Diabetes Mellitus, Type 2; Gene Expression; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Insulin; Insulin Secretion; Insulinoma; Mice; Pancreatic Neoplasms; Peptide Fragments; Peptides; Proinsulin; Promoter Regions, Genetic; RNA, Messenger; Tumor Cells, Cultured | 1992 |
Solubilization of active GLP-1 (7-36)amide receptors from RINm5F plasma membranes.
Topics: Animals; Cations; Detergents; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Insulinoma; Pancreatic Neoplasms; Peptide Fragments; Peptides; Protein Binding; Rats; Receptors, Cell Surface; Receptors, Glucagon; Solubility; Thionucleotides; Tumor Cells, Cultured | 1992 |
Induction of glucose competence in pancreatic beta cells by glucagon-like peptide-1(7-37).
Topics: Animals; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Membrane Potentials; Models, Biological; Peptide Fragments; Peptides; Potassium Channels; Rats; Receptors, Cell Surface; Receptors, Glucagon | 1992 |
Antidiabetogenic effect of glucagon-like peptide-1 (7-36)amide in normal subjects and patients with diabetes mellitus.
Topics: Adult; Aged; Blood Glucose; C-Peptide; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Eating; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Insulin Infusion Systems; Insulin Secretion; Male; Middle Aged; Obesity; Peptide Fragments; Peptides; Somatostatin | 1992 |
An experimental study on the gastric acid and gut hormone secretion after pylorus preserving duodenectomy in dogs.
Topics: Animals; Blood Glucose; Digestive System; Dogs; Gastric Acid; Gastric Inhibitory Polypeptide; Gastrins; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Glucose Tolerance Test; Insulin; Pancreas; Pancreaticoduodenectomy | 1992 |
Autoradiographic localization of receptors for glucagon-like peptide-1 (7-36) amide in rat brain.
Topics: Animals; Brain Chemistry; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Male; Neurotransmitter Agents; Peptide Fragments; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Glucagon | 1992 |
Characterization of binding sites for oxyntomodulin on a somatostatin-secreting cell line (RIN T3).
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Animals; Binding Sites; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Glucagon; Glucagon-Like Peptides; Insulinoma; Iodine Radioisotopes; Oxyntomodulin; Rats; Somatostatin; Tumor Cells, Cultured | 1992 |
Galanin inhibits proinsulin gene expression stimulated by the insulinotropic hormone glucagon-like peptide-I(7-37) in mouse insulinoma beta TC-1 cells.
Topics: Adenylate Cyclase Toxin; Animals; Blotting, Northern; Cell Line; Chloramphenicol O-Acetyltransferase; Colforsin; Galanin; Gene Expression; Gene Expression Regulation, Neoplastic; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Insulinoma; Kinetics; Mice; Models, Biological; Pancreatic Neoplasms; Peptide Fragments; Peptides; Pertussis Toxin; Proinsulin; RNA, Neoplasm; Transfection; Virulence Factors, Bordetella | 1992 |
Glucagonlike peptide-1(7-36)amide suppresses glucagon secretion and decreases cyclic AMP concentration in cultured In-R1-G9 cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Clone Cells; Cricetinae; Cyclic AMP; Dose-Response Relationship, Drug; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Insulinoma; Kinetics; Pancreatic Neoplasms; Peptide Fragments; Peptides | 1992 |
Advances in diabetes research.
Topics: Antidepressive Agents; Demyelinating Diseases; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Humans; Nerve Degeneration; Neuralgia; Peptides; Research | 1992 |
Discussing the role of glucagonlike peptide-I.
Topics: Diabetes Mellitus, Type 2; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Peptide Fragments; Protein Precursors | 1992 |
Comparison of the insulinotropic activity of glucagon-superfamily peptides in rat pancreas perfusion.
Topics: Amino Acid Sequence; Animals; Dose-Response Relationship, Drug; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Growth Hormone-Releasing Hormone; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Molecular Sequence Data; Peptide Fragments; Rats; Rats, Wistar; Sequence Homology, Amino Acid; Vasoactive Intestinal Peptide | 1992 |
Interaction of glucagon-like peptide-1(7-36) amide and gastric inhibitory polypeptide or cholecystokinin on insulin and glucagon secretion from the isolated perfused rat pancreas.
Topics: Animals; Drug Interactions; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Peptide Fragments; Peptides; Perfusion; Rats; Rats, Inbred Strains; Sincalide; Time Factors | 1992 |
The enteroinsular axis revisited. A novel role for an incretin.
Topics: Blood Glucose; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Insulin Secretion; Peptide Fragments; Peptides | 1992 |
Gut regulatory peptides and intestinal permeability in acute infantile gastroenteritis.
Topics: Acute Disease; Gastroenteritis; Glucagon; Glucagon-Like Peptides; Humans; Infant; Intestinal Absorption; Tyrosine | 1992 |
Comparison of the effect of GIP and GLP-1 (7-36amide) on insulin release from rat pancreatic islets.
Topics: Animals; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Peptide Fragments; Peptides; Rats; Rats, Inbred Strains | 1992 |
[A case of hyperinsulinemia due to hypersecretion of incretin].
Topics: Aged; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Tolerance Test; Humans; Hyperinsulinism; Insulin; Insulin Secretion; Male; Peptide Fragments; Protein Precursors | 1992 |
Endocrine response to intragastric and intravenous glucose challenge in the denervated dog pancreas.
Topics: Animals; Blood Glucose; Denervation; Dogs; Gastric Inhibitory Polypeptide; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glucose Tolerance Test; Injections, Intravenous; Insulin; Insulin Secretion; Islets of Langerhans; Pancreas; Pancreas Transplantation; Pancreatic Polypeptide; Peptide Fragments; Transplantation, Autologous | 1992 |
Nutrient-independent increases in proglucagon and ornithine decarboxylase messenger RNAs after jejunoileal resection.
Topics: Adaptation, Physiological; Animals; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Ileum; Jejunum; Male; Ornithine Decarboxylase; Peptide Fragments; Proglucagon; Protein Precursors; Rats; Rats, Inbred Strains; RNA, Messenger | 1992 |
Absence of insulinotropic glucagon-like peptide-I(7-37) receptors on isolated rat liver hepatocytes.
Topics: Animals; Calcium; Cyclic AMP; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Gluconeogenesis; In Vitro Techniques; Liver; Male; Peptide Fragments; Peptides; Phosphorylase a; Rats; Rats, Inbred Strains; Tumor Cells, Cultured | 1991 |
Glucagonlike peptide-I-(7-36)-amide receptors only in islets of Langerhans. Autoradiographic survey of extracerebral tissues in rats.
Topics: Animals; Autoradiography; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Iodine Radioisotopes; Islets of Langerhans; Male; Peptide Fragments; Peptides; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Glucagon; Stomach | 1991 |
[Quantification of gut-associated schistosome circulating proteoglycan and its specific immune complexes in patients with schistosomiasis japonicum].
Topics: Animals; Antibodies, Monoclonal; Antigen-Antibody Complex; Antigens, Helminth; Enzyme-Linked Immunosorbent Assay; Glucagon-Like Peptides; Humans; Peptides; Proteoglycans; Schistosoma japonicum; Schistosomiasis japonica | 1991 |
Functional receptors for the insulinotropic hormone glucagon-like peptide-I(7-37) on a somatostatin secreting cell line.
Topics: Animals; Binding, Competitive; Cell Line; Cyclic AMP; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Glucose; Hormones; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Peptide Fragments; Peptides; Proglucagon; Protein Precursors; Rats; Receptors, Cell Surface; Receptors, Glucagon; Secretory Rate; Somatostatin | 1991 |
Developmental patterns of glucagon-like peptide-1-(7-36) amide and peptide-YY in rat pancreas and gut.
Topics: Aging; Animals; Animals, Newborn; Chromatography, Gel; Fetus; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Insulin; Intestinal Mucosa; Intestines; Pancreas; Peptide Fragments; Peptide YY; Peptides; Radioimmunoassay; Rats; Rats, Inbred Strains; Somatostatin | 1991 |
Oxyntomodulin and related peptides control somatostatin secretion in RIN T3 cells.
Topics: Animals; Calcium; Carbachol; Cyclic AMP; Dose-Response Relationship, Drug; Glucagon; Glucagon-Like Peptides; In Vitro Techniques; Inositol Phosphates; Insulinoma; Oxyntomodulin; Peptide Fragments; Rats; Secretory Rate; Somatostatin; Time Factors; Tumor Cells, Cultured | 1991 |
Interaction of glucagon-like peptide-1 (7-36)amide and cholecystokinin-8 in the endocrine and exocrine rat pancreas.
Topics: Amylases; Animals; Drug Synergism; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; In Vitro Techniques; Islets of Langerhans; Male; Pancreas; Peptide Fragments; Peptides; Rats; Rats, Inbred Strains; Sincalide | 1990 |
Biological and clinicopathological significance of endocrine differentiation of gastric adenocarcinoma evaluated by double immunohistochemical labeling for chromogranin A and bromodeoxyuridine.
Topics: Adenocarcinoma; Bromodeoxyuridine; Cell Differentiation; Cell Division; Chromogranin A; Chromogranins; Gastrins; Glicentin; Glucagon; Glucagon-Like Peptides; Glycoprotein Hormones, alpha Subunit; Hormones; Humans; Immunohistochemistry; Lymph Nodes; Lymphatic Metastasis; Peptide Fragments; Protein Precursors; Serotonin; Somatostatin; Stomach Neoplasms | 1990 |
Priming effect of glucagon-like peptide-1 (7-36) amide, glucose-dependent insulinotropic polypeptide and cholecystokinin-8 at the isolated perfused rat pancreas.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Line; Colforsin; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; In Vitro Techniques; Islets of Langerhans; Kinetics; Male; Peptide Fragments; Peptides; Perfusion; Rats; Rats, Inbred Strains; Sincalide | 1991 |
GLP-1-(7-36) amide, -(1-37), and -(1-36) amide: potent cAMP-dependent stimuli of rat parietal cell function.
Topics: 1-Methyl-3-isobutylxanthine; Aminopyrine; Animals; Biological Transport; Bucladesine; Carbachol; Colforsin; Cyclic AMP; Female; Gastric Acid; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Histamine; In Vitro Techniques; Inositol Phosphates; Kinetics; Parietal Cells, Gastric; Peptide Fragments; Peptides; Pertussis Toxin; Rats; Rats, Inbred Strains; Virulence Factors, Bordetella | 1991 |
Effects of glucagon-like peptide 1 (7-36) amide and glucagon on amylin release from perfused rat pancreas.
Topics: Amyloid; Animals; Dose-Response Relationship, Drug; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Homeostasis; Insulin; Islet Amyloid Polypeptide; Male; Pancreas; Peptide Fragments; Peptides; Perfusion; Radioimmunoassay; Rats; Rats, Inbred Strains | 1991 |
Hyperglycaemia but not hyperinsulinaemia prevents the secretion of glucagon-like peptide-1 (7-36 amide) stimulated by fat ingestion.
Topics: Adult; Analysis of Variance; Blood Glucose; Chromatography, Gel; Dietary Fats; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Hyperglycemia; Injections, Intravenous; Insulin; Peptide Fragments; Peptides | 1991 |
Glucagon 1-21 reduces intestinal epithelial cell proliferation in parenterally fed rats.
Topics: Animals; Cell Division; Digestive System; Epithelium; Gastrins; Glucagon; Glucagon-Like Peptides; Insulin; Intestinal Mucosa; Intestine, Small; Male; Organ Size; Peptide Fragments; Peptide YY; Peptides; Rats; Rats, Inbred Strains | 1991 |
Detection of proinsulin, C-peptide, insulin-A-chain, and glicentin in pancreatic islet cells of early human fetogenesis.
Topics: Antibodies; C-Peptide; Gestational Age; Glicentin; Glucagon; Glucagon-Like Peptides; Humans; Immunoenzyme Techniques; Insulin; Islets of Langerhans; Peptide Fragments; Proinsulin; Protein Precursors | 1991 |
GLP-1(7-36) amide stimulates insulin secretion in rat islets: studies on the mode of action.
Topics: Alkaloids; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Peptide Fragments; Peptides; Protein Kinase C; Rats; Rats, Inbred Strains; Staurosporine | 1991 |
The structure-function relationship of GLP-1 related peptides in the endocrine function of the canine pancreas.
Topics: Animals; Atropine; Dogs; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Peptide Fragments; Peptides; Protein Precursors; Structure-Activity Relationship | 1991 |
Characterization of glucagon-like peptide-I(7-36)amide receptors of rat lung membranes by covalent cross-linking.
Topics: Animals; Cell Membrane; Cells, Cultured; Cross-Linking Reagents; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Ligands; Lung; Molecular Weight; Peptide Fragments; Peptides; Rats; Receptors, Cell Surface; Receptors, Glucagon; Succinimides | 1991 |
Interaction of salmon glucagon, glucagon-like peptide, and epinephrine in the stimulation of phosphorylase a activity in fish isolated hepatocytes.
Topics: Animals; Catfishes; Epinephrine; Fishes; Glucagon; Glucagon-Like Peptides; Glucose; Liver; Peptides; Phosphorylase a; Propranolol; Salmon; Trout | 1991 |
The primary structure of glucagon-like peptide but not insulin has been conserved between the American eel, Anguilla rostrata and the European eel, Anguilla anguilla.
Topics: Amino Acid Sequence; Anguilla; Animals; Chromatography, High Pressure Liquid; Glucagon-Like Peptides; Insulin; Mass Spectrometry; Molecular Sequence Data; Pancreas; Peptide Fragments; Peptides; Species Specificity; Trypsin | 1991 |
GLP-1(7-36)amide-stimulated insulin secretion in rat islets is sodium-dependent.
Topics: Animals; Calcium; Cells, Cultured; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Peptide Fragments; Peptides; Rats; Rats, Inbred Strains; Rubidium; Sodium | 1991 |
GLP-1 and GLP-1(7-36) amide: influences on basal and stimulated insulin and glucagon secretion in the mouse.
Topics: Animals; Blood Glucose; Carbachol; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Immunohistochemistry; Insulin; Insulin Secretion; Intestines; Mice; Mice, Inbred Strains; Pancreas; Peptide Fragments; Peptides; Protein Precursors; Reference Values; Sincalide | 1991 |
Emptying of the gastric substitute, glucagon-like peptide-1 (GLP-1), and reactive hypoglycemia after total gastrectomy.
Topics: Blood Glucose; Dumping Syndrome; Eating; Gastrectomy; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Hypoglycemia; Insulin; Peptide Fragments; Protein Precursors | 1991 |
Effect of the entero-pancreatic hormones, gastric inhibitory polypeptide and glucagon-like polypeptide-1(7-36) amide, on fatty acid synthesis in explants of rat adipose tissue.
Topics: Adipose Tissue; Animals; Culture Techniques; Fatty Acids; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Insulin; Male; Neuropeptides; Peptide Fragments; Peptides; Rats | 1991 |
Inhibition of gastric acid secretion by jejunal glucose and its relation to osmolality and glucose load.
Topics: Adult; Female; Gastric Acid; Glucagon; Glucagon-Like Peptides; Glucose; Humans; Jejunum; Male; Middle Aged; Neurotensin; Osmolar Concentration; Pentagastrin; Saline Solution, Hypertonic; Somatostatin | 1990 |
Molecular and cellular analysis of a neoplastic pancreatic A cell tumor.
Topics: Adenoma, Islet Cell; Blotting, Northern; Chromatography, High Pressure Liquid; Culture Techniques; Cytoplasm; Glicentin; Glucagon; Glucagon-Like Peptides; Glucagonoma; Humans; Immunohistochemistry; Insulin; Microscopy, Electron; Oxyntomodulin; Pancreatic Neoplasms; Peptide Fragments; Proglucagon; Protein Precursors; RNA, Neoplasm; Somatostatin | 1990 |
A glucagon-secretin-like peptide stimulates the intrinsic nervous plexus of guinea pig gallbladder.
Topics: Animals; Female; Gallbladder; Glucagon; Glucagon-Like Peptides; Growth Hormone-Releasing Hormone; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neural Inhibition; Neurotransmitter Agents; Peptides; Receptors, Gastrointestinal Hormone; Receptors, Vasoactive Intestinal Peptide; Secretin; Sermorelin; Vasoactive Intestinal Peptide | 1990 |
Depressed tubular adenoma of the stomach: pathological and immunohistochemical features.
Topics: Adenoma; Antigens, Tumor-Associated, Carbohydrate; Carcinoembryonic Antigen; Glicentin; Glucagon; Glucagon-Like Peptides; Humans; Immunohistochemistry; Muramidase; Peptide Fragments; Protein Precursors; Serotonin; Somatostatin; Stomach Neoplasms | 1990 |
Immunoreactivity to peptides belonging to the pancreatic polypeptide family (NPY, aPY, PP, PYY) and to glucagon-like peptide in the endocrine pancreas and anterior intestine of adult lampreys, Petromyzon marinus: an immunohistochemical study.
Topics: Amino Acid Sequence; Animals; Gastrointestinal Hormones; Glucagon-Like Peptides; Immunohistochemistry; Intestinal Mucosa; Islets of Langerhans; Lampreys; Molecular Sequence Data; Pancreatic Polypeptide; Peptide Biosynthesis; Peptides | 1991 |
Effects of nutritional state on in vivo lipid and carbohydrate metabolism of coho salmon, Oncorhynchus kisutch.
Topics: Animals; Blood Glucose; Carbohydrate Metabolism; Fasting; Fatty Acids; Food; Glucagon; Glucagon-Like Peptides; Gluconeogenesis; Glucosephosphate Dehydrogenase; Glycogen; Insulin; Lipase; Lipid Metabolism; Liver; NADP; Peptides; Pyruvate Kinase; Salmon | 1991 |
Effects of gastrointestinally derived peptides on concentrations of plasma insulin in sheep.
Topics: Animals; Gastric Inhibitory Polypeptide; Gastrointestinal Hormones; Glucagon-Like Peptides; Glucose; Insulin; Insulin Secretion; Peptides; Sheep | 1990 |
Gut signals for islet hormone release.
Topics: Animals; Cholecystokinin; Digestive System Physiological Phenomena; Gastric Emptying; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Islets of Langerhans; Peptide Fragments; Peptides; Protein Precursors; Rats | 1990 |
Reduced insulinotropic effects of glucagonlike peptide I-(7-36)-amide and gastric inhibitory polypeptide in isolated perfused diabetic rat pancreas.
Topics: Animals; Animals, Newborn; Blood Glucose; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Insulin; Pancreas; Peptide Fragments; Peptides; Perfusion; Rats; Rats, Inbred Strains; Streptozocin | 1990 |
Glucagon-like peptide-I analogs: effects on insulin secretion and adenosine 3',5'-monophosphate formation.
Topics: Animals; Cell Line; Cyclic AMP; Dose-Response Relationship, Drug; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Insulin; Insulin Secretion; Insulinoma; Male; Pancreas; Peptide Fragments; Peptides; Rats; Rats, Inbred Strains | 1990 |
Characterization of receptors for glucagon-like peptide-1(7-36)amide on rat lung membranes.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Kinetics; Lung; Male; Peptide Fragments; Peptides; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Glucagon | 1990 |
Glucagon-like peptide-1(7-36)amide: characterization of the domain responsible for binding to its receptor on rat insulinoma RINm5F cells.
Topics: Animals; Binding Sites; Cyclic AMP; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Peptide Fragments; Peptides; Rats; Receptors, Cell Surface; Receptors, Glucagon; Tumor Cells, Cultured | 1990 |
Dexamethasone pretreatment of rat insulinoma cells decreases binding of glucagon-like peptide-1(7-36)amide.
Topics: Animals; Cyclic AMP; Dexamethasone; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucocorticoids; Insulinoma; Mifepristone; Pancreatic Neoplasms; Peptide Fragments; Peptides; Protein Binding; Rats; Time Factors; Tumor Cells, Cultured | 1990 |
Glucagon-like peptide-1(7-37) does not stimulate either hepatic glycogenolysis or ketogenesis.
Topics: Animals; Cyclic AMP; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glycogen; Ketones; Liver; Male; Peptide Fragments; Peptides; Rats; Rats, Inbred Strains | 1990 |
Suppression of synthesis and release of glucagon by glucagon-like peptide-1 (7-36 amide) without affect on mRNA level in isolated rat islets.
Topics: Animals; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; In Vitro Techniques; Islets of Langerhans; Kinetics; Male; Peptide Fragments; Peptides; Proglucagon; Protein Precursors; Rats; Rats, Inbred Strains; RNA, Messenger | 1990 |
Plasma glucose, ketone bodies, insulin, glucagon and enteroglucagon in cows: diurnal variations related to ketone levels before feeding and to the ketogenic effects of feeds.
Topics: Animal Feed; Animals; Blood Glucose; Cattle; Glucagon; Glucagon-Like Peptides; Insulin; Ketone Bodies | 1990 |
Comparison of GLP-1 (7-36amide) and GIP on release of somatostatin-like immunoreactivity and insulin from the isolated rat pancreas.
Topics: Animals; Blood Glucose; Dose-Response Relationship, Drug; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Insulin; Pancreas; Peptide Fragments; Peptides; Perfusion; Rats | 1990 |
Carbachol priming increases glucose- and glucagon-like peptide-1 (7-36)amide-, but not arginine-induced insulin secretion from the isolated perfused rat pancreas.
Topics: Animals; Arginine; Blood Glucose; Carbachol; Dose-Response Relationship, Drug; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Insulin; Male; Pancreas; Peptide Fragments; Peptides; Perfusion; Rats; Stimulation, Chemical | 1990 |
Metabolic clearance rates of oxyntomodulin and glucagon in the rat: contribution of the kidney.
Topics: Animals; Blood Glucose; Chromatography, High Pressure Liquid; Glucagon; Glucagon-Like Peptides; Kidney; Male; Metabolic Clearance Rate; Oxyntomodulin; Radioimmunoassay; Rats; Rats, Inbred Strains; Swine | 1990 |
Effects of truncated glucagon-like peptide-1 on pancreatic hormone release in normal conscious dogs.
Topics: Animals; Blood Glucose; Dogs; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Insulin; Kinetics; Pancreatic Hormones; Peptide Fragments; Peptides | 1990 |
[Progress of gastrin research--from gene to big gastrin N-terminal fragment].
Topics: Amino Acid Sequence; Chromatography; Gastric Mucosa; Gastrins; Glicentin; Glucagon; Glucagon-Like Peptides; Histamine; Humans; Molecular Sequence Data; Omeprazole; Peptide Fragments; Protein Conformation; Protein Precursors; Stomach Ulcer | 1990 |
[Digestive tract hormones and pancreatic secretion].
Topics: Animals; Arginine; Blood Glucose; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Insulin Secretion; Intestines; Mice; Pancreatic Hormones; Peptide Fragments; Peptides; Protein Precursors; Rats; Sincalide | 1990 |
Glucagon-like peptide-1 (7-36)-NH2: a physiological inhibitor of gastric acid secretion in man.
Topics: Adult; Depression, Chemical; Female; Gastric Acid; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Male; Pentagastrin; Peptide Fragments; Peptides; Secretory Rate; Time Factors | 1990 |
Hyperparathyroidism and gastroenteropancreatic hormone levels.
Topics: Adult; Aged; Female; Gastrins; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Humans; Hyperparathyroidism; Male; Middle Aged; Motilin; Multiple Endocrine Neoplasia; Pancreatic Hormones; Pancreatic Polypeptide; Parathyroid Glands; Somatostatin; Substance P; Vasoactive Intestinal Peptide | 1985 |
Cellular localization of proglucagon/glucagon-like peptide I messenger RNAs in rat brain.
Topics: Animals; Brain Chemistry; DNA; DNA, Single-Stranded; Glucagon; Glucagon-Like Peptides; Nucleic Acid Hybridization; Pancreas; Peptides; Proglucagon; Protein Precursors; Rats; RNA, Messenger; Staining and Labeling | 1986 |
Control of glucagon-like immunoreactive peptide secretion from fetal rat intestinal cultures.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Calcimycin; Cells, Cultured; Cobalt; Ethers; Fetus; Gastrointestinal Hormones; Glucagon-Like Peptides; Intestinal Mucosa; Intestines; Ionomycin; Kinetics; Magnesium; Magnesium Chloride; Peptides; Phorbol Esters; Rats; Rats, Inbred Strains | 1988 |
Chronic pancreatitis and diabetes mellitus: plasma and gastroduodenal mucosal profiles of regulatory peptides (gastrin, motilin, secretin, cholecystokinin, gastric inhibitory polypeptide, somatostatin, VIP, substance P, pancreatic polypeptide, glucagon, e
Topics: Adult; Chronic Disease; Diabetes Mellitus; Female; Gastric Inhibitory Polypeptide; Gastric Mucosa; Gastrins; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Humans; Intestinal Mucosa; Male; Middle Aged; Motilin; Neurotensin; Pancreatic Polypeptide; Pancreatitis; Secretin; Somatostatin; Substance P; Vasoactive Intestinal Peptide | 1988 |
Characterization of the receptor for glucagon-like peptide-1(7-36)amide on plasma membranes from rat insulinoma-derived cells by covalent cross-linking.
Topics: Adenoma, Islet Cell; Animals; Cell Line; Cell Membrane; Cross-Linking Reagents; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Insulinoma; Peptides; Rats; Receptors, Cell Surface; Receptors, Glucagon | 1989 |
Signal transmission after GLP-1(7-36)amide binding in RINm5F cells.
Topics: Adenoma, Islet Cell; Animals; Calcium; Cell Line; Cell Membrane; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Insulinoma; Membrane Potentials; Peptide Fragments; Peptides; Rats; Signal Transduction; Tumor Cells, Cultured | 1989 |
Internalization of glucagon-like peptide-1(7-36)amide in rat insulinoma cells.
Topics: Adenoma, Islet Cell; Animals; Chloroquine; Chromatography, High Pressure Liquid; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Insulinoma; Kinetics; Pancreatic Neoplasms; Peptides; Rats; Receptors, Cell Surface; Receptors, Glucagon; Temperature; Tumor Cells, Cultured | 1989 |
Comparison of the effects of glucagon-like peptide-1-(1-37) and -(7-37) and glucagon on islet hormone release from isolated perfused canine and rat pancreases.
Topics: Animals; Cell Separation; Dogs; Dose-Response Relationship, Drug; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Insulin; Islets of Langerhans; Male; Pancreas; Peptide Fragments; Peptides; Perfusion; Rats; Rats, Inbred Strains; Somatostatin | 1989 |
Metabolic changes in coho and chinook salmon resulting from acute insufficiency in pancreatic hormones.
Topics: Animals; Blood Glucose; Carbohydrate Metabolism; Glucagon; Glucagon-Like Peptides; Immune Sera; Insulin; Lipase; Lipid Metabolism; Liver; Liver Glycogen; Pancreatic Hormones; Peptides; Pyruvate Kinase; Salmon; Somatostatin; Triiodothyronine | 1989 |
High-affinity GABA uptake in a subpopulation of somatostatin cells in rat pancreas.
Topics: Animals; Autoradiography; Cholecystokinin; Cytoplasmic Granules; gamma-Aminobutyric Acid; Glicentin; Glucagon; Glucagon-Like Peptides; Immunohistochemistry; Islets of Langerhans; Microscopy, Electron; Pancreatic Polypeptide; Peptide Fragments; Protein Precursors; Rats; Rats, Inbred Strains; Somatostatin | 1989 |
[A case of multiple endocrine neoplasia, type 1, with parathyroid adenoma, multinodular adrenal cortical hyperplasia, islet cell tumor and hyperplasia of thyroid with concomitant hypersecretion of gastrin and total glucagon-like immunoreactivity].
Topics: Adenoma; Adenoma, Islet Cell; Adrenal Cortex; Female; Gastrins; Glucagon-Like Peptides; Humans; Hydrocortisone; Hyperplasia; Middle Aged; Multiple Endocrine Neoplasia; Pancreatic Neoplasms; Parathyroid Neoplasms; Peptides; Thyroid Gland; Thyroid Hormones | 1989 |
Differential regulation of membrane receptors sensitive to histamine (H2-type), isoproterenol (beta 2-type) and glucagon-like peptides by the somatostatin analogue Sandostatin in rat gastric glands.
Topics: Animals; Cyclic AMP; Gastric Mucosa; Glucagon-Like Peptides; In Vitro Techniques; Isoproterenol; Octreotide; Peptides; Rats; Receptors, Adrenergic, beta; Receptors, Gastrointestinal Hormone; Receptors, Glucagon; Receptors, Histamine H2; Somatostatin | 1989 |
Activation of ganglionic tyrosine hydroxylase by peptides of the secretin-glucagon family: structure-function studies.
Topics: Amino Acid Sequence; Animals; Ganglia, Sympathetic; Glucagon-Like Peptides; Growth Hormone-Releasing Hormone; In Vitro Techniques; Intercellular Signaling Peptides and Proteins; Male; Peptides; Rats; Rats, Inbred Strains; Tyrosine 3-Monooxygenase | 1989 |
Interaction of glucagon-like peptide-1(7-36)amide and somatostatin-14 in RINm5F cells and in the perfused rat pancreas.
Topics: Adenoma, Islet Cell; Animals; Cell Line; Cyclic AMP; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Insulin; Insulinoma; Male; Pancreas; Peptide Fragments; Peptides; Rats; Somatostatin; Tumor Cells, Cultured | 1989 |
Effects of glucagonlike peptide I-(7-36) on release of insulin, glucagon, and somatostatin by rat pancreatic islet cell monolayer cultures.
Topics: Animals; Cells, Cultured; Dose-Response Relationship, Drug; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Peptide Fragments; Peptides; Rats; Rats, Inbred Strains; Somatostatin | 1989 |
Presence of glucagon-(1-21)-Like immunoreactive substance in the dog small intestinal mucosa.
Topics: Amino Acid Sequence; Animals; Chromatography, Gel; Chromatography, High Pressure Liquid; Dogs; Glucagon; Glucagon-Like Peptides; Intestinal Mucosa; Intestine, Small; Molecular Sequence Data; Peptide Fragments; Peptides; Radioimmunoassay; Tissue Distribution | 1989 |
Glucagonlike peptide I (7-37) actions on endocrine pancreas.
Topics: Animals; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Peptide Fragments; Peptides; Rats | 1989 |
Metabolic effects of salmon glucagon and glucagon-like peptide in coho and chinook salmon.
Topics: Animals; Carbohydrate Metabolism; Female; Glucagon; Glucagon-Like Peptides; Insulin; Lipid Metabolism; Male; Peptides; Salmon | 1989 |
Glucagonostatic and insulinotropic action of glucagonlike peptide I-(7-36)-amide.
Topics: Animals; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Insulin; Male; Pancreas; Peptide Fragments; Peptides; Rats; Rats, Inbred Strains | 1989 |
Synergistic stimulatory effect of glucagon-like peptide-1 (7-36) amide and glucose-dependent insulin-releasing polypeptide on the endocrine rat pancreas.
Topics: Animals; Drug Synergism; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Peptide Fragments; Peptides; Rats; Rats, Inbred Strains; Stimulation, Chemical | 1989 |
Comparison of the effects of various C-terminal and N-terminal fragment peptides of glucagon-like peptide-1 on insulin and glucagon release from the isolated perfused rat pancreas.
Topics: Animals; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Histidine; Insulin; Insulin Secretion; Male; Pancreas; Peptide Fragments; Peptides; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1989 |
Identification of glucagon-like peptide-1(7-36) amide in rat brain.
Topics: Animals; Brain Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Male; Peptide Fragments; Peptides; Radioimmunoassay; Rats; Rats, Inbred Strains | 1989 |
Effects of acute and chronic ethanol administration on the gastrointestinal hormones gastrin, enteroglucagon, pancreatic glucagon and peptide YY in the rat.
Topics: Animals; Digestive System; Ethanol; Gastrins; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Male; Pancreas; Peptide YY; Peptides; Rats; Rats, Inbred Strains; Time Factors | 1989 |
Characterization of glucagon-like peptide-1-(7-36)amide in the hypothalamus.
Topics: Animals; Diabetes Mellitus, Experimental; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Hypothalamus; Immunohistochemistry; Peptide Fragments; Peptides; Rats; Rats, Inbred Strains | 1989 |
Receptors for glucagon-like peptide-1(7-36) amide on rat insulinoma-derived cells.
Topics: Adenoma, Islet Cell; Animals; Binding, Competitive; Cell Line; Cyclic AMP; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Insulinoma; Intestinal Mucosa; Jejunum; Pancreatic Neoplasms; Peptide Fragments; Peptides; Rats; Receptors, Cell Surface; Receptors, Glucagon | 1988 |
Plasma enteroglucagon and small bowel cytokinetics in rats fed soluble nonstarch polysaccharides.
Topics: Animals; Carboxymethylcellulose Sodium; Cell Division; Dietary Fiber; Galactans; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Intestine, Small; Male; Mannans; Plant Gums; Polysaccharides; Rats; Rats, Inbred Strains | 1988 |
Oxyntomodulin (glicentin-(33-69)): pharmacokinetics, binding to liver cell membranes, effects on isolated perfused pig pancreas, and secretion from isolated perfused lower small intestine of pigs.
Topics: Animals; Cell Membrane; Chromatography, Gel; Chromatography, High Pressure Liquid; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Guinea Pigs; Ileum; In Vitro Techniques; Islets of Langerhans; Liver; Oxyntomodulin; Perfusion; Radioimmunoassay; Receptors, Gastrointestinal Hormone; Receptors, Glucagon | 1988 |
Identification and characterization of glucagon-like peptide-1 7-36 amide-binding sites in the rat brain and lung.
Topics: Animals; Binding, Competitive; Brain; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Kinetics; Lung; Organ Specificity; Peptide Fragments; Peptides; Rats; Rats, Inbred Strains; Receptors, Gastrointestinal Hormone; Receptors, Glucagon | 1988 |
Plasma glucagon-immunoreactive components in early life in dogs.
Topics: Aging; Animals; Animals, Newborn; Arginine; Dogs; Glucagon; Glucagon-Like Peptides; Insulin; Peptides; Radioimmunoassay; Somatostatin | 1985 |
Ectopic G-29 and G-37 glucagon secretion by hypercalcemic infantile renal tumors.
Topics: Animals; Female; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Hormones, Ectopic; Humans; Hypercalcemia; Infant; Kidney Neoplasms; Male; Mice; Mice, Nude; Neoplasm Transplantation; Transplantation, Heterologous; Wilms Tumor | 1986 |
Biological activities of catfish glucagon and glucagon-like peptide.
Topics: Adenylyl Cyclases; Animals; Binding, Competitive; Catfishes; Cell Membrane; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Kinetics; Liver; Male; Peptides; Rats; Rats, Inbred Strains; Receptors, Gastrointestinal Hormone; Receptors, Glucagon | 1987 |
Glucagon-like peptide I stimulates insulin gene expression and increases cyclic AMP levels in a rat islet cell line.
Topics: Actins; Animals; Cell Line; Cyclic AMP; Gastrointestinal Hormones; Gene Expression Regulation; Genes; Glucagon; Glucagon-Like Peptides; Insulin; Islets of Langerhans; Peptides; Rats; RNA, Messenger | 1987 |
Colocalization of glucagon-like peptide and glucagon immunoreactivities in pancreatic islets and intestine of salmonids.
Topics: Animals; Digestive System; Female; Glucagon; Glucagon-Like Peptides; Immunohistochemistry; Islets of Langerhans; Peptides; Salmonidae; Trout | 1988 |
Pancreatic proglucagon processing: isolation and structures of glucagon and glucagon-like peptide from gene I.
Topics: Amino Acid Sequence; Animals; Base Sequence; Chromatography, Gel; Chromatography, High Pressure Liquid; DNA; Fishes; Glucagon; Glucagon-Like Peptides; Islets of Langerhans; Molecular Sequence Data; Peptide Fragments; Peptides; Proglucagon; Protein Precursors; Protein Processing, Post-Translational; Trypsin | 1988 |
Effect of glicentin-related peptides upon the secretion of insulin and glucagon in the canine pancreas.
Topics: Animals; Arginine; Blood Glucose; Dogs; Glicentin; Glucagon; Glucagon-Like Peptides; Insulin; Insulin Secretion; Islets of Langerhans; Peptide Fragments; Protein Precursors; Swine | 1988 |
Absence of the "incretin" phenomenon in the autotransplanted human pancreas.
Topics: Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Insulin Secretion; Middle Aged; Pancreas; Pancreas Transplantation; Peptide Fragments; Transplantation, Autologous | 1988 |
Effect of intraluminal administration of amino acids upon plasma glicentin.
Topics: Amino Acids; Animals; Blood Glucose; Duodenum; Glicentin; Glucagon; Glucagon-Like Peptides; Insulin; Intestinal Secretions; Peptide Fragments; Protein Precursors; Reference Values; Swine | 1988 |
Glucagon-like peptide-1 (7-36 amide): a potent glucagonostatic and insulinotropic hormone.
Topics: Animals; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Insulin; Insulin Secretion; Islets of Langerhans; Male; Peptide Fragments; Peptides; Perfusion; Rats; Rats, Inbred Strains; Reference Values | 1988 |
[Studies on the relation between late dumping syndrome and glucagon responses to glucose].
Topics: Aged; Animals; Blood Glucose; Dogs; Dumping Syndrome; Female; Gastrectomy; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Glucose Tolerance Test; Humans; Hypoglycemia; Insulin; Insulin Secretion; Male; Middle Aged | 1988 |
Development of an oxyntomodulin/glicentin C-terminal radioimmunoassay using a "thiol-maleoyl" coupling method for preparing the immunogen.
Topics: Animals; Antibody Affinity; Chromatography, High Pressure Liquid; Cross Reactions; Gastrointestinal Hormones; Glicentin; Glucagon; Glucagon-Like Peptides; Intestines; Male; Oxyntomodulin; Pancreas; Peptide Fragments; Protein Precursors; Radioimmunoassay; Rats; Rats, Inbred Strains | 1988 |
Oxyntomodulin and glicentin: brain-gut peptides in the rat.
Topics: Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Gastrointestinal Hormones; Glicentin; Glucagon; Glucagon-Like Peptides; Hypothalamus; Intestine, Small; Male; Olfactory Bulb; Oxyntomodulin; Pancreas; Peptide Fragments; Protein Precursors; Radioimmunoassay; Rats; Rats, Inbred Strains; Tissue Distribution | 1988 |
Isolation and characterisation of GLP-1 7-36 amide from rat intestine. Elevated levels in diabetic rats.
Topics: Animals; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Colon; Diabetes Mellitus, Experimental; Eating; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Ileum; Intestinal Mucosa; Intestines; Mass Spectrometry; Molecular Weight; Peptide Fragments; Peptides; Rats; Rats, Inbred Strains; Tissue Distribution | 1988 |
The gastric acid secretagogue gastrin-releasing peptide and the inhibitor oxyntomodulin do not exert their effect directly on the parietal cell in the rat.
Topics: Aminopyrine; Animals; Gastric Acid; Gastrin-Releasing Peptide; Gastrins; Gastrointestinal Hormones; Glicentin; Glucagon; Glucagon-Like Peptides; Histamine; Microscopy, Electron; Oxyntomodulin; Parietal Cells, Gastric; Peptide Fragments; Peptides; Protein Precursors; Rats | 1988 |
Isolation of peptide hormones from the pancreas of the bullfrog (Rana catesbeiana). Amino acid sequences of pancreatic polypeptide, oxyntomodulin, and two glucagon-like peptides.
Topics: Amino Acid Sequence; Amino Acids; Animals; Chromatography, Gel; Chromatography, High Pressure Liquid; Female; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Male; Molecular Sequence Data; Oxyntomodulin; Pancreas; Pancreatic Polypeptide; Rana catesbeiana | 1988 |
Effects of the pathway of bile flow on the digestion of fat and the release of gastrointestinal hormones.
Topics: Adolescent; Adult; Bile; Digestion; Female; Gastric Inhibitory Polypeptide; Gastrins; Gastrointestinal Hormones; Glucagon-Like Peptides; Humans; Insulin; Lipids; Male; Middle Aged; Peptides; Triglycerides | 1988 |
Isolation of alligator gar (Lepisosteus spatula) glucagon, oxyntomodulin, and glucagon-like peptide: amino acid sequences of oxyntomodulin and glucagon-like peptide.
Topics: Amino Acid Sequence; Amino Acids; Animals; Chromatography, Gel; Chromatography, High Pressure Liquid; Female; Fishes; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Islets of Langerhans; Male; Molecular Sequence Data; Oxyntomodulin; Peptides; Radioimmunoassay | 1988 |
Effects of neuromedin B, gastrin-releasing peptide-10 and their fragment peptides on secretion of gastrointestinal and pancreatic hormones in dogs.
Topics: Amino Acid Sequence; Animals; Blood Glucose; Bombesin; Dogs; Gastrins; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Insulin; Insulin Secretion; Neurokinin B; Neuropeptides; Peptide Fragments; Structure-Activity Relationship | 1988 |
Effects of intraduodenal nutrient infusion on insulin response to subsequent intravenous glucose in rats.
Topics: Administration, Oral; Animals; Blood Glucose; Duodenum; Femoral Vein; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Infusions, Intravenous; Injections; Insulin; Insulin Secretion; Male; Peptide Fragments; Portal Vein; Rats; Rats, Inbred Strains | 1987 |
A glucagon-like peptide, structurally related to mammalian oxyntomodulin, from the pancreas of a holocephalan fish, Hydrolagus colliei.
Topics: Amino Acids; Animals; Chromatography, Gel; Chromatography, High Pressure Liquid; Fishes; Glucagon; Glucagon-Like Peptides; Islets of Langerhans; Peptides | 1987 |
Suckling increases insulin and glucagon levels in peripheral venous blood of lactating dogs.
Topics: Animals; Blood Glucose; Dogs; Female; Glucagon; Glucagon-Like Peptides; Insulin; Lactation; Peptides; Pregnancy; Sucking Behavior | 1987 |
Glucagon-like immunoreactive peptides in a rat ileal epithelial cell line (IEC-18).
Topics: Animals; Cell Line; Electrophoresis, Polyacrylamide Gel; Fluorescent Antibody Technique; Gastrointestinal Hormones; Glucagon-Like Peptides; Ileum; Molecular Weight; Peptides; Rats | 1987 |
Trophic effect of glucagon-(1-21)-peptide on the isolated rat ileal mucosal cells.
Topics: Amino Acid Sequence; Animals; Cell Division; Dose-Response Relationship, Drug; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Ileum; Intestinal Mucosa; Male; Peptide Fragments; Peptides; Rats; Rats, Inbred Strains; Thymidine | 1988 |
Distribution of glucagonlike peptide I (GLP-I), glucagon, and glicentin in the rat brain: an immunocytochemical study.
Topics: Animals; Brain; Brain Mapping; Female; Glucagon; Glucagon-Like Peptides; Hypothalamus; Immunohistochemistry; Medulla Oblongata; Peptides; Proglucagon; Protein Precursors; Rats; Rats, Inbred Strains | 1988 |
[Present and future in research of laboratory medicine, metabolism].
Topics: Animals; Glucagon-Like Peptides; Glycoproteins; Glycosuria; Humans; Monitoring, Physiologic; Peptides; Preventive Medicine; Rats | 1988 |
Gastrointestinal hormones and cortisol in normal pregnant women and women with gestational diabetes.
Topics: Female; Gastric Inhibitory Polypeptide; Gastrins; Gastrointestinal Hormones; Glucagon-Like Peptides; Humans; Hydrocortisone; Pancreatic Polypeptide; Peptides; Pregnancy; Pregnancy in Diabetics | 1986 |
Elevation of plasma glucagon-like immunoreactivity (GLI) in patients with liver cirrhosis.
Topics: Adult; Aged; Female; Glucagon; Glucagon-Like Peptides; Glucose Tolerance Test; Humans; Liver Cirrhosis; Male; Middle Aged; Peptides | 1986 |
Regulation of peripheral plasma somatostatin like immunoreactivity in type I diabetes: role of the degree of metabolic control.
Topics: Adolescent; Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 1; Drug Administration Schedule; Fatty Acids, Nonesterified; Female; Glucagon-Like Peptides; Humans; Insulin; Insulin, Regular, Pork; Ketone Bodies; Male; Middle Aged; Peptides | 1986 |
Isolation and structures of coho salmon (Oncorhynchus kisutch) glucagon and glucagon-like peptide.
Topics: Amino Acid Sequence; Animals; Chromatography, Gel; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Islets of Langerhans; Peptides; Salmon | 1986 |
Changes of plasma gastrointestinal glucagon concentrations following lethal infusions of E. coli.
Topics: Animals; Blood Glucose; Blood Pressure; Dogs; Escherichia coli Infections; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Heart Rate; Methylprednisolone Hemisuccinate; Shock, Septic; Tobramycin | 1986 |
Glucagon-like polypeptide and insulin contents in the brain from acute hepatic failure dogs.
Topics: Animals; Blood-Brain Barrier; Brain; Dogs; Glucagon; Glucagon-Like Peptides; Hepatic Encephalopathy; Hypothalamus; Insulin; Male; Peptides; Thalamus; Tissue Distribution | 1986 |
Effect of glicentin-related peptides on glucagon secretion in anaesthetized dogs.
Topics: Animals; Blood Glucose; Dogs; Glicentin; Glucagon; Glucagon-Like Peptides; Insulin; Pancreas; Peptide Fragments; Proglucagon; Protein Precursors | 1986 |
Proglucagon processing in a rat islet cell line resembles phenotype of intestine rather than pancreas.
Topics: Animals; Cell Line; Chromatography, High Pressure Liquid; Gene Expression Regulation; Glucagon; Glucagon-Like Peptides; Intestinal Mucosa; Intestines; Islets of Langerhans; Peptides; Proglucagon; Protein Precursors; Protein Processing, Post-Translational; Rats | 1986 |
Insulinotropin: glucagon-like peptide I (7-37) co-encoded in the glucagon gene is a potent stimulator of insulin release in the perfused rat pancreas.
Topics: Animals; Genes; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Peptide Fragments; Peptides; Rats | 1987 |
Gastrointestinal peptides and insulin secretion.
Topics: Animals; Gastric Inhibitory Polypeptide; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Insulin Secretion; Liver; Neuropeptides; Obesity; Peptide Fragments | 1987 |
Primary structure of glucagon from the gut of the common dogfish (Scyliorhinus canicula).
Topics: Amino Acid Sequence; Animals; Biological Evolution; Dogfish; Glucagon; Glucagon-Like Peptides; Humans; Intestines; Peptides; Sharks; Species Specificity | 1987 |
Distribution of oxyntomodulin and glucagon in the gastrointestinal tract and the plasma of the rat.
Topics: Animals; Chromatography, High Pressure Liquid; Digestive System; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Intestines; Male; Oxyntomodulin; Pancreas; Proglucagon; Protein Precursors; Radioimmunoassay; Radioligand Assay; Rats; Rats, Inbred Strains; Stomach; Tissue Distribution | 1987 |
Effect of ileo-jejunal transposition on intestinal adaptation after total colectomy in dogs.
Topics: Adaptation, Physiological; Animals; Body Weight; Colectomy; Dogs; Gastrins; Glucagon; Glucagon-Like Peptides; Hypertrophy; Ileum; Intestinal Mucosa; Intestines; Jejunum; Peptides | 1987 |
[Studies on hyperglucagonemia in renal failure].
Topics: Animals; Glucagon; Glucagon-Like Peptides; Humans; Kidney Failure, Chronic; Male; Nephrectomy; Peptides; Radioimmunoassay; Rats; Rats, Inbred Strains; Renal Dialysis | 1987 |
Effect of monoclonal antibodies to enteroglucagon on ileal adaptation after proximal small bowel resection.
Topics: Adaptation, Physiological; Animals; Antibodies, Monoclonal; Female; Gastrointestinal Hormones; Glucagon-Like Peptides; Ileum; Intestinal Mucosa; Peptides; Protein Precursors; Rats; Rats, Inbred Strains | 1987 |
Pancreatic polypeptide, pancreatic glucagon and enteroglucagon in morbid obesity and following gastric bypass operation.
Topics: Adult; Female; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Humans; Jejunoileal Bypass; Male; Obesity; Pancreatic Polypeptide | 1986 |
Distribution of glucagon-like peptide I in canine and feline pancreas and gastrointestinal tract.
Topics: Animals; Cats; Digestive System; Dogs; Gastric Mucosa; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Histocytochemistry; Immune Sera; Intestinal Mucosa; Pancreas; Pancreatic Hormones; Peptides; Protein Precursors | 1986 |
Glucagon-related peptides in the rat hypothalamus.
Topics: Animals; Fasting; Glucagon; Glucagon-Like Peptides; Hypothalamus; Immune Sera; Immunoassay; Peptides; Radioimmunoassay; Rats | 1986 |
Inhibition of pentagastrin-stimulated gastric acid secretion by intraileal administration of bile and elevation of plasma concentrations of gut glucagon-like immunoreactivity in anesthetized dogs.
Topics: Animals; Bile; Bile Acids and Salts; Dogs; Female; Gastric Acid; Glucagon-Like Peptides; Ileum; Male; Pentagastrin; Peptides | 1986 |
Plasma glucagon and glucagon-like immunoreactive components in Type 1 (insulin-dependent) diabetic patients and normal subjects before and after an oral glucose load.
Topics: Adult; Amino Acid Sequence; Chromatography, Gel; Diabetes Mellitus, Type 1; Female; Glucagon; Glucagon-Like Peptides; Glucose Tolerance Test; Humans; Male; Peptides | 1985 |
Isolation and structures of glucagon and glucagon-like peptide from catfish pancreas.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Chromatography, High Pressure Liquid; Cross Reactions; Fishes; Glucagon; Glucagon-Like Peptides; Mass Spectrometry; Pancreas; Peptides | 1985 |
Release of glucagon-like immunoreactive material (GLI) from the isolated perfused jejunum of normal and diabetic rats.
Topics: Animals; Diabetes Mellitus, Experimental; Glucagon; Glucagon-Like Peptides; Glucose; In Vitro Techniques; Jejunum; Male; Peptides; Perfusion; Rats; Rats, Inbred Strains | 1985 |
Mouse salivary glands secrete a glucagon-degrading enzyme, not glucagon.
Topics: Animals; Chromatography, Gel; Enzymes; Ethylmaleimide; Glucagon-Like Peptides; Isoproterenol; Male; Mice; Molecular Weight; Peptides; Phenylephrine; Pilocarpine; Saliva; Salivary Glands | 1985 |
Production and characterization of N-terminally and C-terminally directed monoclonal antibodies against pancreatic glucagon.
Topics: Animals; Antibodies, Monoclonal; Antibody Specificity; Chromatography, Gel; Cross Reactions; Digestive System; Female; Glucagon; Glucagon-Like Peptides; Hybridomas; Immunization; Immunoglobulin Idiotypes; Mice; Mice, Inbred BALB C; Peptides; Radioimmunoassay; Rats; Rats, Inbred Strains; Swine | 1985 |
Coexistence of PP- and glucagon-like-immunoreactivity in endocrine cells of gut and pancreas of mouse and a stomachless fish Barbus conchonius.
Topics: Animals; Fishes; Gastrointestinal Hormones; Glucagon-Like Peptides; Mice; Pancreas; Pancreatic Polypeptide; Peptides | 1985 |
Glucagon- and PP-related peptides of intestinal L cells and pancreatic/gastric A or PP cells. Possible interrelationships of peptides and cells during evolution, fetal development and tumor growth.
Topics: Animals; Biological Evolution; Dogs; Gastric Mucosa; Glucagon; Glucagon-Like Peptides; Humans; Intestinal Mucosa; Intestines; Pancreas; Pancreatic Polypeptide; Peptide YY; Peptides; Proglucagon; Protein Precursors; Stomach | 1985 |
Pentagastrin-stimulated gastric acid output and plasma enteroglucagon in acarbose-treated rats.
Topics: Acarbose; Animals; Gastric Acid; Gastrins; Gastrointestinal Hormones; Glucagon-Like Peptides; Glucosidases; Glycoside Hydrolase Inhibitors; Male; Oxyntomodulin; Pentagastrin; Peptides; Rats; Rats, Inbred Strains; Trisaccharides | 1985 |
A glucose-dependent mechanism in jejunum inhibits gastric acid secretion: a response mediated through enteroglucagon?
Topics: Adult; Aged; Dose-Response Relationship, Drug; Female; Gastric Acid; Gastrins; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Glucose; Glucose Solution, Hypertonic; Humans; Injections; Jejunum; Male; Middle Aged; Saline Solution, Hypertonic; Sodium Chloride | 1985 |
Nippostrongylus brasiliensis: changes in plasma levels of gastrointestinal hormones in the infected rat.
Topics: Animals; Body Weight; Cholecystokinin; Energy Intake; Gastrins; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Male; Nematode Infections; Nippostrongylus; Pancreatic Polypeptide; Rats; Secretin | 1985 |
[The APUD concept and its clinical significance. 1].
Topics: APUD Cells; Apudoma; Gastric Inhibitory Polypeptide; Gastrins; Glucagon; Glucagon-Like Peptides; Humans; Insulin; Insulinoma; Motilin; Pancreatic Neoplasms; Secretin | 1982 |
Oxyntomodulin (glucagon-37 or bioactive enteroglucagon): a potent inhibitor of pentagastrin-stimulated acid secretion in rats.
Topics: Animals; Gastric Acid; Gastric Mucosa; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Histamine; Male; Oxyntomodulin; Pentagastrin; Perfusion; Rats; Rats, Inbred Strains; Somatostatin | 1982 |
[The endocrine function of the digestive tract (review). I].
Topics: Animals; APUD Cells; Cholecystokinin; Gastric Inhibitory Polypeptide; Gastrins; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Humans; Motilin; Pancreatic Polypeptide; Peptides; Secretin | 1982 |
Evidence for an indirect effect of somatostatin on glucagon secretion via inhibition of free fatty acids release in the duck.
Topics: Animals; Blood Glucose; Ducks; Fatty Acids, Nonesterified; Glucagon; Glucagon-Like Peptides; Hypophysectomy; Male; Oleic Acid; Oleic Acids; Peptides; Somatostatin | 1983 |
Differential secretion of glucagon-like and somatostatin-like immunoreactivity from the perfused eel pancreas in response to D-glucose.
Topics: Anguilla; Animals; Gastrointestinal Hormones; Glucagon-Like Peptides; Glucose; Islets of Langerhans; Kinetics; Peptides; Perfusion; Somatostatin | 1984 |
Interactions between glucagon and other counterregulatory hormones during normoglycemic and hypoglycemic exercise in dogs.
Topics: Animals; Blood Glucose; Catecholamines; Dogs; Drug Interactions; Fatty Acids, Nonesterified; Female; Glucagon; Glucagon-Like Peptides; Hydrocortisone; Hypoglycemia; Kinetics; Lactates; Lactic Acid; Male; Peptide Biosynthesis; Peptides; Physical Exertion; Somatostatin | 1984 |
[Glicentin carboxyl-terminal specific antiserum].
Topics: Animals; Epitopes; Glicentin; Glucagon; Glucagon-Like Peptides; Peptide Fragments; Proglucagon; Protein Precursors; Rabbits | 1982 |
Regional distribution of bombesin and seven other regulatory peptides in the human brain.
Topics: Adult; Aged; Bombesin; Brain Chemistry; Cholecystokinin; Female; Glucagon; Glucagon-Like Peptides; Humans; Male; Middle Aged; Neurotensin; Neurotransmitter Agents; Peptides; Somatostatin; Substance P; Vasoactive Intestinal Peptide | 1984 |
Excessive circulating large molecular weight immunoreactive glucagon components in subjects with the idiopathic postprandial syndrome.
Topics: Adenoma, Islet Cell; Chromatography, Gel; Food; Glucagon; Glucagon-Like Peptides; Glucose Tolerance Test; Humans; Hypoglycemia; Molecular Weight; Peptides; Syndrome | 1981 |
"Enterolglucagon': a specific effect on gastric glands isolated from the rat fundus. Evidence for an "oxyntomodulin' action.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Cyclic AMP; Exocrine Glands; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Liver; Oxyntomodulin; Rats; Rats, Inbred Strains; Stomach; Terminology as Topic | 1981 |
The effects of exercise on plasma insulin.
Topics: Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Liver; Muscles; Peptide Fragments; Peptides; Physical Education and Training; Physical Exertion; Receptors, Adrenergic, alpha | 1981 |
Bioactive enteroglucagon (oxyntomodulin): present knowledge on its chemical structure and its biological activities.
Topics: Amino Acid Sequence; Animals; Cyclic AMP; Gastric Fundus; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Ileum; Jejunum; Oxyntomodulin; Peptide Fragments; Rats; Swine | 1981 |
A case with glucagonoma syndrome--heterogeneity of glucagon and insulin.
Topics: Adenoma, Islet Cell; Female; Glucagon; Glucagon-Like Peptides; Humans; Insulin; Liver Neoplasms; Middle Aged; Peptides; Radioligand Assay | 1981 |
[Receptor-binding and lipolytic effect of glucagon of the human fetal brain].
Topics: Brain; Brain Chemistry; Glucagon; Glucagon-Like Peptides; Humans; Receptors, Cell Surface; Receptors, Glucagon | 1984 |
Enteroglucagon and GIP after oral glucose in patients with prolactinoma and acromegaly.
Topics: Acromegaly; Adolescent; Adult; Blood Glucose; Female; Gastric Inhibitory Polypeptide; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Glucose Tolerance Test; Humans; Insulin; Male; Middle Aged; Pituitary Neoplasms; Prolactin | 1983 |
Fetal and maternal endocrine responses to exercise in the pregnant ewe.
Topics: Adrenal Cortex Hormones; Animals; Blood Glucose; Female; Fetal Blood; Glucagon; Glucagon-Like Peptides; Growth Hormone; Hormones; Insulin; Kinetics; Lactates; Lactic Acid; Physical Exertion; Pregnancy; Pregnancy, Animal; Sheep | 1983 |
Fasting and postprandial plasma glucagon and glucagon-like immunoreactivity are normal in obese Pima Indians.
Topics: Adult; Blood Glucose; Fasting; Food; Glucagon; Glucagon-Like Peptides; Humans; Indians, North American; Insulin; Middle Aged; Obesity; Peptides | 1983 |
Preservation of incretin activity after removal of gastric inhibitory polypeptide (GIP) from rat gut extracts by immunoadsorption.
Topics: Animals; Antibodies; Gastric Inhibitory Polypeptide; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Immunosorbent Techniques; Infusions, Parenteral; Insulin; Insulin Secretion; Intestinal Mucosa; Male; Peptide Fragments; Peptides; Rats; Rats, Inbred Strains; Time Factors; Tissue Extracts | 1983 |
Relation of enteroinsular hormones at birth to macrosomia and neonatal hypoglycemia in infants of diabetic mothers.
Topics: Adult; Birth Weight; Blood Glucose; Female; Gastric Inhibitory Polypeptide; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Humans; Hypoglycemia; Infant, Newborn; Insulin; Insulin Antibodies; Male; Pancreatic Hormones; Pregnancy; Pregnancy in Diabetics | 1983 |
[Effects of ethanol on secretion of glucagon, especially on gut glucagon-like immunoreactivity].
Topics: Animals; Blood Glucose; Ethanol; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Insulin; Male; Peptides; Rats; Rats, Inbred Strains | 1983 |
Insulin- and glucagonlike peptides in the brain.
Topics: Animals; Anura; Brain Chemistry; C-Peptide; Glucagon; Glucagon-Like Peptides; Humans; Immunologic Techniques; Insulin; Mice; Peptides; Radioimmunoassay; Rats; Somatomedins; Spinal Cord; Turtles | 1983 |
Partial purification of an insulin-releasing activity in human serum.
Topics: Animals; Biological Assay; Child; Chromatography, High Pressure Liquid; Fasting; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Tolerance Test; Humans; In Vitro Techniques; Intercellular Signaling Peptides and Proteins; Islets of Langerhans; Obesity; Peptide Fragments; Peptides; Rats; Rats, Inbred Strains | 1983 |
Diurnal profile of pancreatic polypeptide, pancreatic glucagon, gut glucagon and insulin in human morbid obesity.
Topics: Adult; Animals; Circadian Rhythm; Female; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Humans; Hyperinsulinism; Insulin; Insulin Secretion; Male; Mice; Obesity; Pancreatic Polypeptide | 1983 |
A pure enteroglucagon, oxyntomodulin (glucagon 37), stimulates insulin release in perfused rat pancreas.
Topics: Animals; Dose-Response Relationship, Drug; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; In Vitro Techniques; Insulin; Insulin Secretion; Kinetics; Male; Oxyntomodulin; Pancreas; Perfusion; Rats; Rats, Inbred Strains | 1984 |
The differential effect of intragastric and intravenous tryptophan on plasma glucose, insulin, glucagon, GLI and GIP in the fasted rat.
Topics: Administration, Oral; Animals; Blood Glucose; Fasting; Gastric Inhibitory Polypeptide; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Injections, Intravenous; Insulin; Islets of Langerhans; Male; Peptides; Rats; Rats, Inbred Strains; Tryptophan | 1984 |
Effects of selective vagotomy with or without drainage on glucose tolerance test.
Topics: Adult; Blood Glucose; Drainage; Female; Gastrectomy; Glucagon; Glucagon-Like Peptides; Glucose Tolerance Test; Humans; Insulin; Male; Middle Aged; Peptides; Vagotomy; Vagotomy, Proximal Gastric | 1984 |
Changes in pancreatic hormones associated with coccidiosis.
Topics: Animals; Blood Glucose; Body Weight; Chickens; Coccidiosis; Eimeria; Glucagon; Glucagon-Like Peptides; Insulin; Liver Glycogen; Organ Size; Pancreatic Hormones; Peptides; Pigments, Biological; Poultry Diseases; Species Specificity | 1984 |
Characterization of response of gut GLI to fat ingestion in dogs.
Topics: Animals; Butter; Caprylates; Dietary Fats; Dogs; Glucagon; Glucagon-Like Peptides; Glycerol; Insulin; Palmitic Acid; Palmitic Acids; Pancreas; Pancreatectomy; Peptides; Triglycerides | 1984 |
Stability of endogenous immunoreactive glucagon (IRG) in animal blood.
Topics: Animals; Benzamidines; Dogs; Edetic Acid; Glucagon-Like Peptides; Peptides; Rabbits; Rats; Species Specificity; Time Factors | 1983 |
[Gastric inhibitory polypeptide (GIP), incretin and gastrointestinal diseases].
Topics: Gastric Inhibitory Polypeptide; Gastrointestinal Diseases; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Peptide Fragments; Peptides; Radioimmunoassay | 1984 |
[Big plasma glucagon in patients with liver cirrhosis. The discrepancy in values of immunoreactive glucagon measured by use of two different antisera against pancreatic glucagon, 30K and OAL-123].
Topics: Chromatography, Gel; Glucagon; Glucagon-Like Peptides; Humans; Immune Sera; Liver Cirrhosis; Peptides; Radioimmunoassay | 1984 |
[Nature of "big plasma glucagon" in plasma of human and rats].
Topics: Animals; Chromatography; Glucagon; Glucagon-Like Peptides; Humans; Liver Cirrhosis; Male; Molecular Weight; Peptides; Protease Inhibitors; Radioimmunoassay; Rats; Rats, Inbred Strains | 1984 |
Decreased food intakes and body weights in rats immunized against pancreatic glucagon.
Topics: Animals; Body Weight; Feeding Behavior; Female; Glucagon; Glucagon-Like Peptides; Immunization; Obesity; Rats; Rats, Zucker | 1984 |
Glucagon-related peptides in the human gastrointestinal mucosa.
Topics: Gastric Mucosa; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Humans; Intestinal Mucosa; Peptides; Proglucagon; Protein Precursors; Radioimmunoassay; Radioligand Assay | 1984 |
Synaptosomal localization and release of glucagon-like materials in the rat brain.
Topics: Animals; Brain Chemistry; Brain Stem; Glucagon; Glucagon-Like Peptides; Hypothalamus; Male; Microsomes; Peptides; Rats; Rats, Inbred Strains; Subcellular Fractions; Synaptosomes; Thalamus | 1984 |
Glucagon-like peptides in the CNS of man: localization and possible functional importance.
Topics: Brain; Glucagon-Like Peptides; Histocytochemistry; Humans; Immunochemistry; Peptides; Tissue Distribution | 1984 |
[Effect of prostaglandin F2 alpha (PGF2 alpha) on gastric emptying, small bowel transit time, gut hormone release and blood glucose].
Topics: Adult; Blood Glucose; Dinoprost; Gastric Emptying; Glucagon-Like Peptides; Humans; Intestine, Small; Male; Peptides; Prostaglandins F; Time Factors | 1983 |
Evolution of glucagon genes.
Topics: Animals; Biological Evolution; DNA; Glicentin; Glucagon; Glucagon-Like Peptides; Humans; Multigene Family; Peptide Fragments; Peptides; Protein Precursors | 1984 |
Content and gel filtration profiles of glucagon-like and somatostatin-like immunoreactivity in human fundic mucosa.
Topics: Adult; Aged; Chromatography, Gel; Female; Gastric Fundus; Gastric Mucosa; Glucagon-Like Peptides; Humans; Male; Middle Aged; Peptides | 1983 |
The effect of age and sex on the response of enteropancreatic polypeptides to oral glucose.
Topics: Adult; Aged; Aging; Female; Gastric Inhibitory Polypeptide; Gastrointestinal Hormones; Glucagon-Like Peptides; Glucose Tolerance Test; Humans; Male; Pancreatic Polypeptide; Peptides; Radioimmunoassay; Sex Factors | 1983 |
Heterogeneity of glucagon-like immunoreactive peptides (GLi) in the intestine of obese hyperglycaemic (ob/ob) mice.
Topics: Animals; Chromatography, Gel; Glucagon-Like Peptides; Hyperglycemia; Intestines; Mice; Mice, Obese; Obesity; Peptides | 1983 |
[The effects of oral ethanol administration on plasma gut GLI in rats].
Topics: Administration, Oral; Animals; Blood Glucose; Ethanol; Glucagon-Like Peptides; Peptides; Rats; Rats, Inbred Strains | 1983 |
Immunological specificity and biological action of biliary glucagon-like substance in the rabbit.
Topics: Animals; Bile; Blood Glucose; Cholestasis; Glucagon; Glucagon-Like Peptides; Male; Mice; Mice, Inbred Strains; Peptides; Rabbits; Rats; Rats, Inbred Strains | 1983 |
[Behavior of total plasma immunoreactive glucagon in 2 total pancreatectomy patients].
Topics: Arginine; Diabetes Mellitus; Glucagon; Glucagon-Like Peptides; Glucose Tolerance Test; Humans; Male; Middle Aged; Pancreatectomy; Peptides | 1983 |
[Glucagon-like-immunoreactivity and enteroglucagon, with special reference to immunohistochemical observation].
Topics: Animals; Dogs; Female; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Humans; Islets of Langerhans; Male; Middle Aged; Peptides; Protein Precursors | 1982 |
Gastric inhibitory polypeptide and insulin release in response to oral and intravenous glucose in coeliac disease.
Topics: Adult; Blood Glucose; Celiac Disease; Female; Gastric Inhibitory Polypeptide; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Tolerance Test; Humans; Insulin; Insulin Secretion; Male; Middle Aged; Peptide Fragments; Peptides | 1982 |
Pancreatic and gastrointestinal hormones in chronic pancreatitis.
Topics: Adult; Blood Glucose; Chronic Disease; Female; Gastric Inhibitory Polypeptide; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Humans; Insulin; Male; Middle Aged; Motilin; Pancreatic Hormones; Pancreatic Polypeptide; Pancreatitis | 1982 |
Hormonal and metabolic effects of intravenous infusion of prostacyclin in healthy women.
Topics: Adolescent; Adult; Epoprostenol; Female; Glucagon; Glucagon-Like Peptides; Gonadal Steroid Hormones; Humans; Infusions, Parenteral; Insulin; Pituitary Hormones; Prostaglandins; Renin; Thyroid Hormones | 1982 |
[Bioactive "enteroglucagon" (oxyntomodulin): evidence for a C-terminal extension of the glucagon molecule].
Topics: Amino Acid Sequence; Amino Acids; Animals; Chromatography, High Pressure Liquid; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Histidine; Ileum; Jejunum; Oxyntomodulin; Peptide Fragments; Swine | 1981 |
Molecular forms of human enteroglucagon in tissue and plasma: plasma responses to nutrient stimuli in health and in disorders of the upper gastrointestinal tract.
Topics: Adult; Celiac Disease; Chromatography, Gel; Digestive System; Dumping Syndrome; Female; Food; Gastrointestinal Diseases; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Humans; Immune Sera; Male; Middle Aged; Pancreas; Radioimmunoassay; Sprue, Tropical; Tissue Distribution | 1983 |
The glucagon-like polypeptides - order out of chaos?
Topics: Glucagon; Glucagon-Like Peptides; Humans; Molecular Weight; Peptides; Radioimmunoassay; Terminology as Topic | 1980 |
Evidence that glicentin contains the entire sequence of glucagon.
Topics: Amino Acid Sequence; Animals; Chromatography, Gel; Glucagon; Glucagon-Like Peptides; Immune Sera; Peptides; Swine; Trypsin | 1980 |
The primary structure of porcine glicentin (proglucagon).
Topics: Amino Acid Sequence; Animals; Chemical Phenomena; Chemistry; Glicentin; Glucagon; Glucagon-Like Peptides; Models, Chemical; Molecular Weight; Pancreas; Peptide Fragments; Peptides; Proglucagon; Protein Precursors; Swine | 1981 |
Effects of amino-acids on pancreatic hormones and gut glucagon-like immunoreactivity in the goose.
Topics: Alanine; Animals; Arginine; Female; Geese; Glucagon-Like Peptides; Injections, Intravenous; Male; Pancreas; Pancreatic Hormones; Peptides | 1982 |
Renal metabolism of gut glucagon-like immunoreactivity.
Topics: Animals; Chromatography, Gel; Dogs; Duodenum; Glucagon-Like Peptides; Glucose; Kidney; Male; Nephrectomy; Peptides; Perfusion; Rats | 1982 |
Glucagon-like immunoreactants in extracts of the rat hypothalamus.
Topics: Animals; Body Weight; Chromatography, Gel; Diabetes Mellitus, Experimental; Fasting; Glucagon-Like Peptides; Hypothalamus; Male; Molecular Weight; Peptides; Rats; Rats, Inbred Strains | 1982 |
Glycoprotein-like large glucagon immunoreactive species in extracts of the fetal bovine pancreas.
Topics: Animals; Cattle; Chromatography, Affinity; Chromatography, Gel; Fetus; Glucagon; Glucagon-Like Peptides; Glycoproteins; Pancreas; Peptides; Radioimmunoassay | 1982 |
[Peptidergic system in the vertebrate retina. III. Glucagonergic neuron system in the chicken retina].
Topics: Animals; Chickens; Glucagon-Like Peptides; Peptides; Retina | 1982 |
Angioplastic necrolytic migratory erythema. Unique association of necrolytic migratory erythema, extensive angioplasia, and high molecular weight glucagon-like polypeptide.
Topics: Adult; Autoradiography; Biopsy; Diabetes Complications; Erythema; Glucagon-Like Peptides; Glucagonoma; Humans; Male; Pancreatic Neoplasms; Peptides; Skin; Thymidine; Tritium | 1982 |
Production of antisera to des Asn28 Thr29 Homoser27-glucagon; the development of radioimmunoassay for total glucagon-like immunoreactivity in human plasma.
Topics: Animals; Cross Reactions; Dogs; Gastrectomy; Glucagon; Glucagon-Like Peptides; Humans; Immune Sera; Immunization; Intestines; Peptides; Rabbits; Radioimmunoassay; Tissue Extracts | 1981 |
Effect of porcine ileal glucagon-like immunoreactivity & glucagon on glucose output by liver.
Topics: Animals; Female; Glucagon; Glucagon-Like Peptides; Glucose; Liver; Peptides; Perfusion; Rats; Swine | 1982 |
A pancreatic polypeptide (PP)-like immunoreactant is present in the glicentin-containing cell of the cat intestine.
Topics: Animals; Cats; Cytoplasmic Granules; Fluorescent Antibody Technique; Glucagon-Like Peptides; Histocytochemistry; Intestinal Mucosa; Microscopy, Electron; Pancreas; Pancreatic Polypeptide; Peptides | 1980 |
Simultaneous recording of the gastro-entero-pancreatic hormonal peptide response to food in man.
Topics: Adult; Food; Gastric Inhibitory Polypeptide; Gastrins; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Humans; Insulin; Kinetics; Male; Pancreatic Hormones; Pancreatic Polypeptide; Secretin; Vasoactive Intestinal Peptide | 1980 |
Immunoreactive glucagon and insulin C-peptide in man after resection of the pancreas and total pancreatectomy.
Topics: Adult; Aged; Arginine; C-Peptide; Chronic Disease; Female; Glucagon; Glucagon-Like Peptides; Humans; Insulin; Male; Middle Aged; Pancreas; Pancreatectomy; Pancreatitis; Peptides; Radioimmunoassay | 1980 |
Glicentin and gastric inhibitory polypeptide immunoreactivity in endocrine cells of the gut and pancreas.
Topics: Aging; Animals; Cats; Dogs; Duodenum; Female; Gastric Inhibitory Polypeptide; Gastric Mucosa; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Histocytochemistry; Immune Sera; Immunoassay; Insulin; Intestinal Mucosa; Intestine, Small; Male; Pancreas; Peptides; Rats | 1980 |
Hormonal changes after gastric surgery.
Topics: Bradykinin; Cholecystokinin; Gastrectomy; Gastric Inhibitory Polypeptide; Gastrins; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Humans; Insulin; Insulin Secretion; Neurotensin; Secretin; Serotonin; Vagotomy | 1980 |
The broadening incretin concept.
Topics: Blood Glucose; Food; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Insulin Secretion; Peptide Fragments; Peptides | 1980 |
Glucagon- and glicentin-immunoreactive cells in the human digestive tract.
Topics: Cytoplasmic Granules; Glucagon; Glucagon-Like Peptides; Humans; Intestinal Mucosa; Intestine, Small; Islets of Langerhans; Peptides | 1980 |
Effects of glicentine on insulin secretion.
Topics: Animals; Carbachol; Dose-Response Relationship, Drug; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptides; Glucose; Insulin; Insulin Secretion; Mice; Peptides | 1980 |
Gastrointestinal insulinotropic hormones in normal and gestational-diabetic pregnancy: response to oral glucose.
Topics: Blood Glucose; Body Weight; Female; Gastric Inhibitory Polypeptide; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Glucose; Humans; Insulin; Peptides; Pregnancy; Pregnancy in Diabetics; Reference Values | 1981 |
Changes in N-terminal glucagon-like immunoreactivity and insulin during short-term gluten challenge in childhood coeliac disease.
Topics: Adolescent; Blood Glucose; Celiac Disease; Child; Child, Preschool; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Glutens; Humans; Insulin; Peptides | 1981 |
A qualitative comparison of canine plasma gastroenteropancreatic hormone response to bombesin and the porcine gastrin-releasing peptide (GRP).
Topics: Animals; Blood Glucose; Bombesin; Dogs; Gastric Inhibitory Polypeptide; Gastrin-Releasing Peptide; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Insulin; Motilin; Pancreatic Polypeptide; Peptides; Swine | 1981 |
[Coeliac sprue and gut hormones: pathophysiological and clinical aspects (author's transl)].
Topics: Adult; Blood Glucose; Celiac Disease; Female; Gastric Inhibitory Polypeptide; Gastrins; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Humans; Insulin; Insulin Secretion; Male; Middle Aged; Motilin; Neurotensin; Pancreatic Polypeptide; Secretin; Vasoactive Intestinal Peptide | 1981 |
The amino acid sequence of porcine glicentin.
Topics: Amino Acid Sequence; Cysteine Endopeptidases; Endopeptidases; Glicentin; Glucagon; Glucagon-Like Peptides; Peptide Fragments; Proglucagon; Protein Precursors | 1981 |
Purification and chemical characterization of a glicentin-related pancreatic peptide (proglucagon fragment) from porcine pancreas.
Topics: Amino Acid Sequence; Amino Acids; Animals; Chromatography, High Pressure Liquid; Glicentin; Glucagon; Glucagon-Like Peptides; Molecular Weight; Pancreas; Peptide Fragments; Protein Precursors; Swine | 1982 |
Evidence that enteroglucagon (II) is identical with the C-terminal sequence (residues 33-69) of glicentin.
Topics: Amino Acid Sequence; Animals; Chromatography, Gel; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Peptide Fragments; Proglucagon; Protein Precursors; Swine | 1982 |
Gut-hormone profile in totally pancreatectomised patients.
Topics: Adult; Blood Glucose; Female; Gastric Inhibitory Polypeptide; Gastrins; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Humans; Male; Middle Aged; Motilin; Neurotensin; Pancreatectomy; Pancreatic Polypeptide | 1981 |
Exaggerated response of plasma glucagon-like immunoreactivity (GLI) to oral glucose in patients with reactive hypoglycemia.
Topics: Glucagon; Glucagon-Like Peptides; Glucose; Glucose Tolerance Test; Humans; Hypoglycemia; Peptic Ulcer | 1981 |
Signal transduction of the GLP-1-receptor cloned from a human insulinoma.
Topics: Amino Acid Sequence; Animals; Blotting, Northern; Calcium; Cell Line; Cloning, Molecular; Cyclic AMP; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulinoma; Molecular Sequence Data; Peptide Fragments; Rats; Receptors, Glucagon; Recombinant Proteins; RNA; Sequence Homology, Amino Acid; Signal Transduction; Transfection | 1994 |
[Glucagon peptide--new treatment for late-onset diabetes?].
Topics: C-Peptide; Diabetes Mellitus, Type 2; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Humans; Hypoglycemic Agents; Insulin; Insulin Secretion; Pancreatic Hormones; Peptides; Protein Precursors | 1994 |
Failure of GLP-1(7-36)amide to affect glycogenesis in rat skeletal muscle.
Topics: Animals; Biological Transport; Carbon Dioxide; Deoxyglucose; Dose-Response Relationship, Drug; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glycogen; In Vitro Techniques; Insulin; Lactates; Male; Muscle, Skeletal; Peptide Fragments; Rats; Rats, Sprague-Dawley | 1995 |
Glucagon-like peptide-1 binding to rat hepatic membranes.
Topics: Animals; Autoradiography; Binding, Competitive; Cell Membrane; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Insulin; Liver; Peptide Fragments; Peptides; Protein Binding; Rats; Rats, Wistar | 1995 |
Regulation of glucagon-like peptide-1-(7-36) amide, peptide YY, and neurotensin secretion by neurotransmitters and gut hormones in the isolated vascularly perfused rat ileum.
Topics: Animals; Bethanechol; Bombesin; Calcitonin Gene-Related Peptide; Gastric Inhibitory Polypeptide; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Ileum; Isoproterenol; Male; Neurotensin; Neurotransmitter Agents; Parasympathomimetics; Peptide Fragments; Peptide YY; Peptides; Perfusion; Rats; Rats, Wistar; Tetrodotoxin | 1995 |
Stimulation of cloned human glucagon-like peptide 1 receptor expressed in HEK 293 cells induces cAMP-dependent activation of calcium-induced calcium release.
Topics: Acetylcholine; Calcium; Calcium Channel Blockers; Cell Line; Cloning, Molecular; Cyclic AMP; Embryo, Mammalian; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Humans; Ionomycin; Kidney; Peptide Fragments; Receptors, Glucagon; Recombinant Proteins; Ryanodine; Thionucleotides | 1995 |
Differential processing of proglucagon by the subtilisin-like prohormone convertases PC2 and PC3 to generate either glucagon or glucagon-like peptide.
Topics: Amino Acid Sequence; Animals; Aspartic Acid Endopeptidases; Cell Line; Chlorocebus aethiops; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Kinetics; L Cells; Mice; Molecular Sequence Data; Peptide Biosynthesis; Peptide Fragments; Peptides; Proglucagon; Proprotein Convertase 2; Proprotein Convertases; Protein Precursors; Protein Processing, Post-Translational; Recombinant Proteins; Substrate Specificity; Subtilisins; Transfection | 1995 |
Insulinotropic actions of intravenous glucagon-like peptide-1 (GLP-1) [7-36 amide] in the fasting state in healthy subjects.
Topics: Adult; Analysis of Variance; C-Peptide; Dose-Response Relationship, Drug; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Infusions, Intravenous; Insulin; Insulin Secretion; Kinetics; Male; Peptide Fragments; Reference Values; Time Factors | 1995 |
Highly increased insulin secretion in a patient with postprandial hypoglycemia: role of glucagon-like peptide-1 (7-36) amide.
Topics: Adult; C-Peptide; Fasting; Food; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Tolerance Test; Humans; Hypoglycemia; Insulin; Insulin Secretion; Male; Peptide Fragments; Proinsulin | 1995 |
Degradation of glucose-dependent insulinotropic polypeptide and truncated glucagon-like peptide 1 in vitro and in vivo by dipeptidyl peptidase IV.
Topics: Animals; Blood Physiological Phenomena; Dipeptidyl Peptidase 4; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Peptide Fragments; Peptides; Protein Precursors; Rats; Rats, Inbred F344; Rats, Wistar | 1995 |
Luminal glucagon-like peptide-1(7-36) amide-releasing factors in the isolated vascularly perfused rat colon.
Topics: Animals; Bile Acids and Salts; Colon; Deoxycholic Acid; Dose-Response Relationship, Drug; Fatty Acids, Volatile; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; In Vitro Techniques; Male; Pectins; Peptide Fragments; Rats; Rats, Wistar | 1995 |
Both subcutaneously and intravenously administered glucagon-like peptide I are rapidly degraded from the NH2-terminus in type II diabetic patients and in healthy subjects.
Topics: Adult; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Enzyme-Linked Immunosorbent Assay; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Infusions, Intravenous; Injections, Subcutaneous; Male; Middle Aged; Peptide Fragments; Radioimmunoassay; Reference Values; Sensitivity and Specificity; Time Factors | 1995 |
Glucose-dependent action of glucagon-like peptide-1 (7-37) in vivo during short- or long-term administration.
Topics: Animals; Blood Glucose; Dose-Response Relationship, Drug; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Clamp Technique; Infusion Pumps; Insulin; Kinetics; Male; Peptide Fragments; Peptides; Rats; Rats, Sprague-Dawley | 1995 |
Effect of intestinal inhibitory peptides on vagally induced secretion from isolated perfused porcine pancreas.
Topics: Animals; Calcitonin Gene-Related Peptide; Electric Stimulation; Galanin; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; In Vitro Techniques; Neuropeptide Y; Oxyntomodulin; Pancreas; Peptide Fragments; Peptide YY; Peptides; Perfusion; Protein Precursors; Somatostatin; Swine; Vagus Nerve; Vasoactive Intestinal Peptide | 1993 |
Amylin alters the biological action of the incretin hormone GLP-1(7-36)amide.
Topics: Adenylyl Cyclases; Amyloid; Animals; Cell Line; Colforsin; Cyclic AMP; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Intolerance; Insulinoma; Islet Amyloid Polypeptide; Islets of Langerhans; Models, Biological; Peptide Fragments; Peptides; Rats; Substance P | 1993 |
Peptidergic innervation and endocrine cells in the human liver.
Topics: Adult; Aged; Female; Galanin; Gastrins; Glucagon; Glucagon-Like Peptides; Hodgkin Disease; Humans; Immunohistochemistry; Liver; Male; Middle Aged; Nerve Fibers; Neurofilament Proteins; Neuropeptide Y; Neuropeptides; Neurotensin; Peptides; Phosphopyruvate Hydratase; S100 Proteins; Serotonin; Somatostatin; Substance P; Vasoactive Intestinal Peptide | 1993 |
Insulin secretion and plasma levels of glucose-dependent insulinotropic peptide and glucagon-like peptide 1 [7-36 amide] after oral glucose in cirrhosis.
Topics: Adult; Blood Glucose; C-Peptide; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Humans; Insulin; Insulin Secretion; Liver Cirrhosis; Male; Middle Aged; Peptide Fragments | 1995 |
Altered glucose dependence of glucagon-like peptide I(7-36)-induced insulin secretion from the Zucker (fa/fa) rat pancreas.
Topics: Animals; Diabetes Mellitus, Experimental; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glucose Tolerance Test; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Obesity; Peptide Fragments; Perfusion; Rats; Rats, Zucker | 1995 |
Effects of glucose-dependent insulinotropic polypeptide and glucagon-like peptide-I-(7-36) on insulin secretion.
Topics: Animals; Chromatography, High Pressure Liquid; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Male; Pancreas; Peptide Fragments; Rats; Rats, Wistar; Swine | 1995 |
Glucagon-like peptide-1 and glucose-dependent insulin-releasing polypeptide plasma levels in response to nutrients.
Topics: Adult; Amino Acids; Animals; Diet; Fats; Food; Galactose; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Humans; Insulin; Insulin Secretion; Male; Peptide Fragments; Peptides; Protein Precursors; Rats; Rats, Wistar | 1995 |
A novel procedure for the preparation of biologically active recombinant peptides using a cyanylation reaction.
Topics: Amino Acid Sequence; Base Sequence; Escherichia coli; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Molecular Sequence Data; Peptide Biosynthesis; Peptide Fragments; Peptides; Plasmids; Recombinant Fusion Proteins | 1994 |
Comparative effects of GLP-1-(7-36) amide, oxyntomodulin and glucagon on rabbit gastric parietal cell function.
Topics: Aminopyrine; Animals; Blotting, Northern; Cyclic AMP; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Histamine; Oxyntomodulin; Parietal Cells, Gastric; Peptide Fragments; Rabbits; RNA, Messenger; Somatostatin | 1995 |
Glucagon-like peptide-1 binding to rat skeletal muscle.
Topics: Adenylyl Cyclases; Animals; Binding, Competitive; Cell Membrane; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Insulin; Muscle, Skeletal; Peptide Fragments; Protein Precursors; Rats; Rats, Wistar; Receptor, Insulin; Receptors, Glucagon | 1995 |
Glucagon-like peptide I increases cytoplasmic calcium in insulin-secreting beta TC3-cells by enhancement of intracellular calcium mobilization.
Topics: Animals; Calcium; Calcium Channels; Cell Line; Colforsin; Cyclic AMP; Cytoplasm; Dose-Response Relationship, Drug; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Inositol Phosphates; Insulin; Insulin Secretion; Insulinoma; Islets of Langerhans; Kinetics; Mice; Mice, Transgenic; Pancreatic Neoplasms; Peptide Fragments; Ryanodine; Time Factors; Tumor Cells, Cultured | 1995 |
Structural characterization by affinity cross-linking of glucagon-like peptide-1(7-36)amide receptor in rat brain.
Topics: Animals; Brain Chemistry; Brain Stem; Cell Membrane; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Hypothalamus; Lung; Male; Peptide Fragments; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, Glucagon | 1995 |
Reduction of the incretin effect in rats by the glucagon-like peptide 1 receptor antagonist exendin (9-39) amide.
Topics: Animals; Drug Interactions; Exenatide; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Glucose; Insulin; Male; Peptide Fragments; Peptides; Protein Precursors; Radioimmunoassay; Rats; Rats, Wistar; Receptors, Glucagon; Venoms | 1995 |
Glucagon-like peptide-1 (GLP-1): a piece of the incretin puzzle.
Topics: Animals; Diabetes Mellitus, Type 2; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Peptide Fragments; Peptides; Protein Precursors; Rodentia | 1995 |
Glucagon-like peptide-1 is a physiological incretin in rat.
Topics: Anesthesia; Animals; Arginine; Cells, Cultured; Consciousness; Eating; Fasting; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Glucose; Infusions, Intravenous; Insulin; Insulin Secretion; Male; Pancreas; Peptide Fragments; Peptides; Protein Precursors; Radioligand Assay; Rats; Rats, Wistar; Receptors, Glucagon; Vasoactive Intestinal Peptide | 1995 |
Exendin-4 and exendin-(9-39)NH2: agonist and antagonist, respectively, at the rat parietal cell receptor for glucagon-like peptide-1-(7-36)NH2.
Topics: Aminopyrine; Animals; Binding, Competitive; Cell Membrane; Cross-Linking Reagents; Cyclic AMP; Exenatide; Female; Gastric Acid; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Histamine; In Vitro Techniques; Lizards; Parietal Cells, Gastric; Peptide Fragments; Peptides; Rats; Rats, Wistar; Receptors, Glucagon; Venoms | 1994 |
Glucagon-like peptide-1 (7-36)amide and glucose-dependent insulinotropic polypeptide secretion in response to nutrient ingestion in man: acute post-prandial and 24-h secretion patterns.
Topics: Adult; Blood Glucose; Circadian Rhythm; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; Eating; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Humans; Insulin; Lipid Metabolism; Nutritional Physiological Phenomena; Peptide Fragments; Radioimmunoassay; Time Factors | 1993 |
Insulinotropic action of human glicentin in dogs.
Topics: Animals; Arginine; Dogs; Dose-Response Relationship, Drug; Glicentin; Glucagon; Glucagon-Like Peptides; Glucose; Insulin; Peptide Fragments; Protein Precursors; Recombinant Proteins | 1995 |
Glucagon-like peptide-1 modulates Ca2+ current but not K+ATP current in intact mouse pancreatic B-cells.
Topics: Adenosine Triphosphate; Animals; Calcium Channels; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; In Vitro Techniques; Islets of Langerhans; Kinetics; Membrane Potentials; Mice; Mice, Inbred Strains; Peptide Fragments; Peptides; Potassium Channels; Protein Precursors | 1995 |
Investigations into the actions of glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1(7-36)amide on lipoprotein lipase activity in explants of rat adipose tissue.
Topics: Adipose Tissue; Animals; Culture Techniques; Dactinomycin; Enzyme Activation; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Insulin; Lipoprotein Lipase; Male; Peptide Fragments; Rats; Rats, Wistar | 1995 |
The role of prohormone convertases PC1 (PC3) and PC2 in the cell-specific processing of proglucagon.
Topics: Animals; Aspartic Acid Endopeptidases; Base Sequence; Blotting, Northern; Cell Line; Chromatography, High Pressure Liquid; DNA Primers; Glucagon; Glucagon-Like Peptides; Insulinoma; Molecular Sequence Data; Oxyntomodulin; Pancreatic Neoplasms; Peptide Fragments; Pituitary Neoplasms; Polymerase Chain Reaction; Proglucagon; Proprotein Convertase 2; Proprotein Convertases; Protein Precursors; Protein Processing, Post-Translational; Rats; RNA, Messenger; Subtilisins; Transfection | 1995 |
Potent glycogenic effect of GLP-1(7-36)amide in rat skeletal muscle.
Topics: Animals; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glycogen; Glycogen Synthase; Insulin; Lactates; Lactic Acid; Muscle, Skeletal; Neurotransmitter Agents; Peptide Fragments; Phosphorylase a; Rats; Rats, Wistar | 1994 |
Gastric inhibitory polypeptide and glucagon-like peptide-1(7-36) amide exert similar effects on somatostatin secretion but opposite effects on gastrin secretion from the rat stomach.
Topics: Animals; Gastric Inhibitory Polypeptide; Gastric Mucosa; Gastrins; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; In Vitro Techniques; Male; Peptide Fragments; Peptides; Rats; Rats, Wistar; Swine | 1994 |
An immunohistochemical study of enteropancreatic endocrine cells in larvae and juveniles of the southern-hemisphere lampreys Geotria australis and Mordacia mordax.
Topics: Animals; Endocrine Glands; Glucagon; Glucagon-Like Peptides; Immune Sera; Immunohistochemistry; Insulin; Islets of Langerhans; Lampreys; Larva; Neuropeptide Y; Pancreatic Polypeptide; Peptides; Somatostatin | 1993 |
Interaction of glucagon-like peptide-I (7-37) and somatostatin-14 on signal transduction and proinsulin gene expression in beta TC-1 cells.
Topics: Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Drug Interactions; Gene Expression; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Insulinoma; Mice; Pancreatic Neoplasms; Peptides; Proinsulin; Receptors, Cell Surface; Receptors, Glucagon; Signal Transduction; Somatostatin; Tumor Cells, Cultured | 1994 |
Rat gastric somatostatin and gastrin release: interactions of exendin-4 and truncated glucagon-like peptide-1 (GLP-1) amide.
Topics: Animals; Exenatide; Gastric Juice; Gastrins; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; In Vitro Techniques; Male; Peptide Fragments; Peptides; Rats; Rats, Sprague-Dawley; Somatostatin; Venoms | 1994 |
Stable expression of the rat GLP-I receptor in CHO cells: activation and binding characteristics utilizing GLP-I(7-36)-amide, oxyntomodulin, exendin-4, and exendin(9-39).
Topics: Animals; CHO Cells; Cricetinae; Evaluation Studies as Topic; Exenatide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Lizards; Neurotransmitter Agents; Oxyntomodulin; Peptide Fragments; Peptides; Rats; Receptors, Cell Surface; Receptors, Glucagon; Venoms | 1994 |
Glycosylation of the GLP-1 receptor is a prerequisite for regular receptor function.
Topics: Amidohydrolases; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Glycosylation; Insulin; Insulin Secretion; Islets of Langerhans; Molecular Weight; Peptide Fragments; Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase; Receptors, Cell Surface; Receptors, Glucagon; Tumor Cells, Cultured; Tunicamycin | 1994 |
Purification and sequence of rat oxyntomodulin.
Topics: Amino Acid Sequence; Animals; Chromatography, High Pressure Liquid; Glucagon; Glucagon-Like Peptides; Humans; Ileum; Intestine, Small; Jejunum; Male; Mass Spectrometry; Molecular Sequence Data; Oligopeptides; Oxyntomodulin; Proglucagon; Protein Precursors; Rats; Rats, Sprague-Dawley; Swine | 1994 |
Rat parietal cell receptors for GLP-1-(7-36) amide: northern blot, cross-linking, and radioligand binding.
Topics: Aminopyrine; Animals; Blotting, Northern; Cell Separation; Cross-Linking Reagents; Exenatide; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Kinetics; Parietal Cells, Gastric; Peptide Fragments; Peptides; Radioligand Assay; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, Glucagon; RNA, Messenger; Venoms | 1994 |
Glucagon-like peptide-1(7-36) amide (GLP-1) enhances insulin-stimulated glucose metabolism in 3T3-L1 adipocytes: one of several potential extrapancreatic sites of GLP-1 action.
Topics: 3T3 Cells; Adipocytes; Animals; Base Sequence; Blotting, Southern; DNA, Complementary; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Insulin; Kidney; Mice; Molecular Sequence Data; Muscle, Skeletal; Peptide Fragments; Polymerase Chain Reaction; RNA, Messenger | 1994 |
FT-IR and near-infrared FT-Raman studies of the secondary structure of insulinotropin in the solid state: alpha-helix to beta-sheet conversion induced by phenol and/or by high shear force.
Topics: Amino Acid Sequence; Chemical Phenomena; Chemistry, Physical; Chromatography, High Pressure Liquid; Circular Dichroism; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humidity; Molecular Sequence Data; Peptide Fragments; Peptides; Phenols; Protein Structure, Secondary; Solubility; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman | 1994 |
Regulation of glucagon-like peptide-1-(7-36) amide secretion by intestinal neurotransmitters and hormones in the isolated vascularly perfused rat colon.
Topics: Animals; Colon; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; In Vitro Techniques; Intestinal Mucosa; Male; Neuropeptides; Neurotransmitter Agents; Peptide Fragments; Perfusion; Rats; Rats, Wistar | 1994 |
Glucose-dependent alterations of intracellular free calcium by glucagon-like peptide-1(7-36amide) in individual ob/ob mouse beta-cells.
Topics: Animals; Calcium; Cyclic AMP; Diabetes Mellitus, Type 2; Felodipine; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; In Vitro Techniques; Islets of Langerhans; Mice; Mice, Inbred C57BL; Peptide Fragments | 1994 |
Proglucagon processing in porcine and human pancreas.
Topics: Amino Acid Sequence; Animals; Glicentin; Glucagon; Glucagon-Like Peptides; Humans; Molecular Sequence Data; Pancreas; Peptide Fragments; Proglucagon; Protein Precursors; Protein Processing, Post-Translational; Swine | 1994 |
The insulinotropic actions of glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (7-37) in normal and diabetic subjects.
Topics: Administration, Oral; Adult; Blood Glucose; Diabetes Mellitus, Type 2; Drug Synergism; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Injections, Intravenous; Insulin; Male; Peptide Fragments; Peptides | 1994 |
Spermine-induced precocious intestinal maturation in suckling rats: possible involvement of glucocorticoids.
Topics: Administration, Oral; Adrenocorticotropic Hormone; Animals; Animals, Suckling; Cholecystokinin; Corticosterone; Disaccharidases; Gastrins; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Intestines; Peptides; Rats; Rats, Wistar; Secretin; Spermine; Stimulation, Chemical | 1994 |
Glucagon-like peptide 1: a potent glycogenic hormone.
Topics: Animals; Cells, Cultured; Cyclic AMP; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glycogen; Glycogen Synthase; Liver; Peptides; Phosphorylases; Rats; Rats, Wistar | 1994 |
Hormonal enteroinsular axis in newborn infants of insulin-treated diabetic mothers.
Topics: Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Digestive System; Enteral Nutrition; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptides; Humans; Infant, Newborn; Insulin; Islets of Langerhans; Male; Milk, Human; Pancreas; Pregnancy; Pregnancy in Diabetics | 1993 |
Dipeptidyl-peptidase IV hydrolyses gastric inhibitory polypeptide, glucagon-like peptide-1(7-36)amide, peptide histidine methionine and is responsible for their degradation in human serum.
Topics: Amino Acid Sequence; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Male; Models, Biological; Molecular Sequence Data; Peptide Fragments; Peptide PHI; Substrate Specificity | 1993 |
Glucagon-like peptide-1-(7-36) amide, oxyntomodulin, and glucagon interact with a common receptor in a somatostatin-secreting cell line.
Topics: Animals; Binding, Competitive; Blotting, Northern; Cell Line; Cell Membrane; Cricetinae; Cross-Linking Reagents; Cyclic AMP; Fibroblasts; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Oxyntomodulin; Peptide Fragments; Receptors, Cell Surface; Receptors, Glucagon; Somatostatin; Transfection | 1993 |
Effects of glucagon-like peptide-1(7-36)amide on the concentrations of insulin and glucose in sheep.
Topics: Animals; Blood Glucose; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Insulin; Male; Peptides; Sheep | 1993 |
Detection of the human glucagon-like peptide 1(7-36) amide receptor on insulinoma-derived cell membranes.
Topics: Animals; Cell Membrane; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Humans; Insulinoma; Islets of Langerhans; Pancreatic Neoplasms; Peptide Fragments; Rats; Receptors, Cell Surface; Receptors, Glucagon; Tumor Cells, Cultured | 1994 |
Structure-activity relationships of glucagon-like peptide-1(7-36)amide: insulinotropic activities in perfused rat pancreases, and receptor binding and cyclic AMP production in RINm5F cells.
Topics: Animals; Cell Line; Cyclic AMP; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Insulin; Insulinoma; Male; Pancreas; Peptide Fragments; Perfusion; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, Glucagon; Stimulation, Chemical; Structure-Activity Relationship | 1994 |
Structure of glucagon-like peptide (7-36) amide in a dodecylphosphocholine micelle as determined by 2D NMR.
Topics: Amides; Amino Acid Sequence; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Kinetics; Magnetic Resonance Spectroscopy; Micelles; Models, Molecular; Molecular Sequence Data; Peptide Fragments; Phosphorylcholine; Protein Structure, Secondary | 1994 |
Proglucagon is processed to glucagon by prohormone convertase PC2 in alpha TC1-6 cells.
Topics: Animals; Cell Line; Glicentin; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; In Vitro Techniques; Islets of Langerhans; Peptide Fragments; Peptides; Proglucagon; Proprotein Convertase 2; Protein Precursors; Protein Processing, Post-Translational; Rats; Subtilisins | 1994 |
Changes in arterial blood pressure and heart rate induced by glucagon-like peptide-1-(7-36) amide in rats.
Topics: Animals; Blood Pressure; Catecholamines; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Heart Rate; Male; Peptide Fragments; Peptides; Rats; Rats, Sprague-Dawley; Reserpine | 1994 |
Immunological detection of prohormone convertases in two different proglucagon processing cell lines.
Topics: Animals; Aspartic Acid Endopeptidases; Cell Line; Chromatography, High Pressure Liquid; Glicentin; Glucagon; Glucagon-Like Peptides; Immunoblotting; Intestines; Islets of Langerhans; Mice; Mice, Transgenic; Peptide Fragments; Proglucagon; Proprotein Convertase 1; Proprotein Convertase 2; Proprotein Convertases; Protein Precursors; Radioimmunoassay; Subtilisins; Tumor Cells, Cultured | 1994 |
Glucagon-like peptide 1 enhances glucose tolerance both by stimulation of insulin release and by increasing insulin-independent glucose disposal.
Topics: Adult; Blood Glucose; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Tolerance Test; Humans; Infusions, Intravenous; Insulin; Male; Middle Aged; Peptide Fragments | 1994 |
Adaptation of enteroendocrine cells in response to jejunal-ileal transposition in the rat.
Topics: Adaptation, Physiological; Animals; Biomarkers; Carrier Proteins; Endocrine Glands; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; Gastrins; Glucagon-Like Peptides; Ileum; Immunohistochemistry; Intestinal Mucosa; Intestines; Jejunum; Liver; Male; Neoplasm Proteins; Nerve Tissue Proteins; Peptides; Rats; Rats, Sprague-Dawley; Transplantation, Heterotopic | 1994 |
Stimulation of rat parietal cell function by histamine and GLP-1-(7-36) amide is mediated by Gs alpha.
Topics: Adenosine Diphosphate; Adenylyl Cyclases; Aminopyrine; Animals; Cell Membrane; Cell Separation; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; GTP-Binding Proteins; Histamine; Kinetics; Molecular Weight; Parietal Cells, Gastric; Peptide Fragments; Rats; Rats, Wistar | 1994 |
Structure and biological activity of glucagon and glucagon-like peptide from a primitive bony fish, the bowfin (Amia calva).
Topics: Amino Acid Sequence; Animals; Fishes; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glycogen; Humans; Liver; Molecular Sequence Data; Pancreas; Peptide Fragments; Peptides; Sequence Homology, Amino Acid | 1993 |
Presence of glucagon and glucagon-like peptide-1-(7-36)amide receptors in solubilized membranes of human adipose tissue.
Topics: Adipose Tissue; Aged; Cell Membrane; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Humans; Male; Middle Aged; Peptide Fragments; Receptors, Cell Surface; Receptors, Glucagon | 1993 |
Effects of glucagon like peptide-1(7-36) amide on the cytoplasmic Ca(2+)-concentration in rat islet cells.
Topics: Animals; Calcium; Cytoplasm; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Islets of Langerhans; Male; Peptide Fragments; Rats; Rats, Sprague-Dawley; Spectrometry, Fluorescence | 1993 |
Plasma enteroglucagon levels in different models of intestinal resection in the rat.
Topics: Adaptation, Physiological; Animals; Glucagon; Glucagon-Like Peptides; Glucose; Ileum; Intestinal Mucosa; Jejunum; Male; Rats; Rats, Wistar | 1994 |
Regulation of intestinal proglucagon-derived peptide secretion by glucose-dependent insulinotropic peptide in a novel enteroendocrine loop.
Topics: Animals; Corn Oil; Duodenum; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Ileum; Infusions, Intravenous; Intestinal Secretions; Kinetics; Male; Peptide Fragments; Peptides; Rats; Rats, Wistar | 1993 |
Glucose dependent insulinotropic polypeptide and glucagon-like peptide-1(7-36)amide: effects on lipoprotein lipase activity.
Topics: Adipose Tissue; Animals; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Insulin; Lipoprotein Lipase; Peptide Fragments; Rats | 1993 |
Presence and characterization of glucagon-like peptide-1(7-36) amide receptors in solubilized membranes of rat adipose tissue.
Topics: Adipose Tissue; Animals; Binding, Competitive; Cell Membrane; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Kinetics; Male; Peptide Fragments; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, Glucagon; Solubility; Temperature | 1993 |
The role of the free cytosolic calcium level in beta-cell signal transduction by gastric inhibitory polypeptide and glucagon-like peptide I(7-37).
Topics: Animals; Calcium; Cricetinae; Cyclic AMP; Cytosol; Egtazic Acid; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Insulin; Insulin Secretion; Islets of Langerhans; Nimodipine; Peptide Fragments; Peptides; Phosphatidylinositols; Signal Transduction; Tumor Cells, Cultured | 1993 |
Pancreatic beta-cells are rendered glucose-competent by the insulinotropic hormone glucagon-like peptide-1(7-37).
Topics: Animals; Cells, Cultured; Cyclic AMP; Drug Synergism; Electric Conductivity; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glyburide; Islets of Langerhans; Male; Membrane Potentials; Peptide Fragments; Peptides; Rats; Thionucleotides | 1993 |
Amino-terminal parathyroid hormone-related protein: specific binding and cytosolic calcium responses in rat insulinoma cells.
Topics: Animals; Binding Sites; Calcium; Cell Membrane; Cyclic AMP; Cytosol; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glyburide; Insulinoma; Kinetics; Pancreatic Neoplasms; Parathyroid Hormone; Parathyroid Hormone-Related Protein; Peptide Fragments; Peptides; Proteins; Rats; Rats, Inbred WF; Tumor Cells, Cultured | 1993 |
Solubilization of active receptors for glucagon-like peptide-1(7-36)amide from rat lung membranes.
Topics: Animals; Cations; Cell Membrane; Cross-Linking Reagents; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Guanine Nucleotides; Hydrogen-Ion Concentration; Lung; Male; Peptide Fragments; Rats; Receptors, Cell Surface; Receptors, Glucagon; Solubility | 1993 |
Possible role of the adrenergic mechanism in gastric inhibitory polypeptide- and glucagon-like peptide-1 (7-36) amide-induced insulin release in the rat.
Topics: Animals; Blood Glucose; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Insulin; Insulin Secretion; Male; Peptide Fragments; Propranolol; Rats; Rats, Wistar; Receptors, Adrenergic, beta | 1993 |
Functional expression of the rat glucagon-like peptide-I receptor, evidence for coupling to both adenylyl cyclase and phospholipase-C.
Topics: Adenylyl Cyclases; Animals; Calcium; Cell Line; Chlorocebus aethiops; Cyclic AMP; Gene Expression; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Kidney; Peptide Fragments; Peptides; Phosphatidylinositols; Rats; Receptors, Cell Surface; Receptors, Glucagon; RNA, Messenger; Type C Phospholipases | 1993 |
Neuropeptide Y expression and regulation in a differentiated rat insulin-secreting cell line.
Topics: Adenylyl Cyclases; Animals; Cell Differentiation; Clonidine; Colforsin; Cyclic AMP; Enzyme Activation; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation, Neoplastic; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Insulin; Insulin Secretion; Insulinoma; Neuropeptide Y; Pancreatic Neoplasms; Peptide Fragments; Protein Kinase C; Rats; Receptors, Neuropeptide Y; Tumor Cells, Cultured | 1993 |
Exendin-4 is a high potency agonist and truncated exendin-(9-39)-amide an antagonist at the glucagon-like peptide 1-(7-36)-amide receptor of insulin-secreting beta-cells.
Topics: Animals; Binding, Competitive; Cell Line; Cell Membrane; Cyclic AMP; Exenatide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Insulin; Insulin Secretion; Insulinoma; Kinetics; Lizards; Lung; Pancreatic Neoplasms; Peptide Fragments; Peptides; Rats; Receptors, Cell Surface; Receptors, Glucagon; Tumor Cells, Cultured; Venoms | 1993 |
Binding specificity and signal transduction of receptors for glucagon-like peptide-1(7-36)amide and gastric inhibitory polypeptide on RINm5F insulinoma cells.
Topics: Animals; Binding Sites; Binding, Competitive; Cell Line; Cyclic AMP; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Islets of Langerhans; Peptide Fragments; Rats; Receptors, Cell Surface; Receptors, Gastrointestinal Hormone; Receptors, Glucagon; Signal Transduction | 1993 |
Glucagon-like peptide-1-(7-36)amide and a rise in cyclic adenosine 3',5'-monophosphate increase cytosolic free Ca2+ in rat pancreatic beta-cells by enhancing Ca2+ channel activity.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Cyclic AMP; Cytosol; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Islets of Langerhans; Nitrendipine; Osmolar Concentration; Peptide Fragments; Rats | 1993 |
Pancreas and gut hormone responses to oral glucose and intravenous glucagon in cystic fibrosis patients with normal, impaired, and diabetic glucose tolerance.
Topics: Administration, Oral; Adult; C-Peptide; Cystic Fibrosis; Diabetes Complications; Diabetes Mellitus; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glucose Tolerance Test; Hormones; Humans; Injections, Intravenous; Insulin; Intestinal Mucosa; Intestines; Male; Middle Aged; Pancreas; Pancreatic Polypeptide; Peptide Fragments; Proinsulin; Protein Precursors; Time Factors | 1993 |
Biological effects and metabolic rates of glucagonlike peptide-1 7-36 amide and glucagonlike peptide-1 7-37 in healthy subjects are indistinguishable.
Topics: Adult; Blood Glucose; C-Peptide; Fatty Acids, Nonesterified; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Insulin Secretion; Male; Peptide Fragments; Structure-Activity Relationship; Time Factors | 1993 |
Glucose-dependency of the insulin stimulatory effect of glucagon-like peptide-1 (7-36) amide on the rat pancreas.
Topics: Amides; Animals; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Male; Pancreas; Peptide Fragments; Perfusion; Radioimmunoassay; Rats; Rats, Wistar | 1993 |
A role for glucagon-like peptide-1 in the central regulation of feeding.
Topics: Animals; Cerebral Ventricles; Eating; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Injections, Intraventricular; Male; Neuropeptide Y; Peptide Fragments; Proto-Oncogene Proteins c-fos; Rats; Satiation | 1996 |
Glycemic control mechanisms after canine islet autografting.
Topics: Animals; Blood Glucose; Dogs; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Tolerance Test; Insulin; Insulin Secretion; Islets of Langerhans Transplantation; Pancreatectomy; Peptide Fragments; Transplantation, Autologous | 1995 |
Dose-responses for the slowing of gastric emptying in a rodent model by glucagon-like peptide (7-36) NH2, amylin, cholecystokinin, and other possible regulators of nutrient uptake.
Topics: Amino Acids; Amyloid; Animals; Cholecystokinin; Dose-Response Relationship, Drug; Gastric Emptying; Gastric Inhibitory Polypeptide; Gastrointestinal Hormones; Gels; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Islet Amyloid Polypeptide; Male; Pancreatic Polypeptide; Peptide Fragments; Phenolsulfonphthalein; Rats; Rats, Sprague-Dawley | 1996 |
Influence of non-starch polysaccharides on gastrointestinal endocrine mechanisms.
Topics: Animals; Cellulose; Dietary Fiber; Evaluation Studies as Topic; Galactans; Gastrins; Gastrointestinal Hormones; Glucagon-Like Peptides; Gum Arabic; Male; Mannans; Peptides; Plant Gums; Rats; Rats, Wistar | 1995 |
Elimination of the action of glucagon-like peptide 1 causes an impairment of glucose tolerance after nutrient ingestion by healthy baboons.
Topics: Animals; Antibodies, Monoclonal; Blood Glucose; Fasting; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Glucose; Glucose Tolerance Test; Insulin; Male; Papio; Peptide Fragments; Receptors, Glucagon; Xylose | 1996 |
Mechanism of impaired glucose-potentiated insulin secretion in diabetic 90% pancreatectomy rats. Study using glucagonlike peptide-1 (7-37).
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Drug Synergism; Fasting; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Hyperglycemia; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Organ Size; Pancreas; Pancreatectomy; Peptide Fragments; Peptides; Proinsulin; Rats; Rats, Sprague-Dawley; RNA, Messenger; Time Factors | 1996 |
Gastric emptying and release of incretin hormones after glucose ingestion in humans.
Topics: Adult; Blood Glucose; C-Peptide; Duodenum; Gastric Emptying; Gastric Inhibitory Polypeptide; Gastric Mucosa; Gastrointestinal Hormones; Gastrointestinal Motility; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Humans; Insulin; Insulin Secretion; Male; Peptide Fragments | 1996 |
Comparison of sandwich enzyme-linked immunoadsorbent assay and radioimmunoassay for determination of exogenous glucagon-like peptide-1(7-36)amide in plasma.
Topics: Amino Acid Sequence; Animals; Antibodies; Cats; Chromatography, High Pressure Liquid; Dogs; Enzyme-Linked Immunosorbent Assay; Epitopes; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Molecular Sequence Data; Neurotransmitter Agents; Peptide Fragments; Rabbits; Radioimmunoassay; Rats; Reference Values; Sensitivity and Specificity; Sequence Homology, Amino Acid; Swine; Swine, Miniature | 1995 |
Distribution of GLP-1 binding sites in the rat brain: evidence that exendin-4 is a ligand of brain GLP-1 binding sites.
Topics: Animals; Autoradiography; Binding Sites; Brain; Exenatide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Kinetics; Male; Peptide Fragments; Peptides; Radioligand Assay; Rats; Rats, Wistar; Venoms | 1995 |
GIP and GLP-1(7-36)amide secretion in response to intraduodenal infusions of nutrients in pigs.
Topics: Analysis of Variance; Animals; Blood Glucose; Dietary Fats; Duodenum; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Insulin; Insulin Secretion; Peptide Fragments; Radioimmunoassay; Sodium Chloride; Swine; Triglycerides | 1995 |
Precipitation of insulinotropin in the presence of protamine: effect of phenol and zinc on the isophane ratio and the insulinotropin concentration in the supernatant.
Topics: Animals; Chemical Precipitation; Chromatography, High Pressure Liquid; Circular Dichroism; Drug Compounding; Evaluation Studies as Topic; Excipients; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Hydrogen-Ion Concentration; Peptide Fragments; Peptides; Phenol; Phenols; Protamines; Technology, Pharmaceutical; Zinc | 1995 |
Intra-islet regulation of hormone secretion by glucagon-like peptide-1-(7--36) amide.
Topics: Animals; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Glucose; Hormones; Insulin; Insulin Secretion; Islets of Langerhans; Male; Peptide Fragments; Peptides; Rats; Rats, Sprague-Dawley; Receptors, Glucagon; Somatostatin | 1995 |
Characterisation of the processing by human neutral endopeptidase 24.11 of GLP-1(7-36) amide and comparison of the substrate specificity of the enzyme for other glucagon-like peptides.
Topics: Amino Acid Sequence; Chromatography, High Pressure Liquid; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Kinetics; Molecular Sequence Data; Neprilysin; Peptide Fragments; Protein Processing, Post-Translational; Recombinant Proteins; Sequence Homology, Amino Acid; Substrate Specificity | 1995 |
The application of crystal soaking technique to study the effect of zinc and cresol on insulinotropin crystals grown from a saline solution.
Topics: Amino Acid Sequence; Calorimetry, Differential Scanning; Chemical Phenomena; Chemistry, Physical; Cresols; Crystallization; Crystallography, X-Ray; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Hydrogen-Ion Concentration; Injections, Subcutaneous; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Peptide Fragments; Peptides; Photomicrography; Sodium Chloride; Solubility; Zinc | 1995 |
Simulating the folding of small proteins by use of the local minimum energy and the free solvation energy yields native-like structures.
Topics: Animals; Calcium-Binding Proteins; Cattle; Computer Graphics; Computer Simulation; Crystallography, X-Ray; Glicentin; Glucagon; Glucagon-Like Peptides; Peptide Fragments; Protein Conformation; Protein Folding; Protein Precursors; Protein Structure, Secondary; Solubility; Solvents; Thermodynamics; Uteroglobin | 1995 |
Comparison of the glucose dependency of glucagon-like peptide-1 (7-37) and glyburide in vitro and in vivo.
Topics: Animals; Fasting; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glyburide; Hypoglycemic Agents; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Peptide Fragments; Peptides; Rats; Rats, Sprague-Dawley | 1996 |
The third cytoplasmic domain of the GLP-1[7-36 amide] receptor is required for coupling to the adenylyl cyclase system.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Cell Line; Cyclic AMP; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Protein Conformation; Rats; Receptors, Glucagon; Structure-Activity Relationship | 1996 |
Glucagon-like peptide I receptors in the subfornical organ and the area postrema are accessible to circulating glucagon-like peptide I.
Topics: Animals; Autoradiography; Cerebral Ventricles; Female; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Hypothalamus; Iodine Radioisotopes; Peptides; Protein Precursors; Rats; Rats, Wistar; Receptors, Glucagon; Subfornical Organ | 1996 |
Gastrin-releasing peptide is a novel mediator of proximal nutrient-induced proglucagon-derived peptide secretion from the distal gut.
Topics: Animals; Corn Oil; Dietary Fats; Duodenum; Gastrin-Releasing Peptide; Gastrins; Glucagon; Glucagon-Like Peptides; Intestines; Kinetics; Male; Oligopeptides; Peptide Fragments; Peptides; Proglucagon; Protein Precursors; Rats; Rats, Wistar | 1996 |
Release of glucagon-like peptide 1 (GLP-1 [7-36 amide]), gastric inhibitory polypeptide (GIP) and insulin in response to oral glucose after upper and lower intestinal resections.
Topics: Adult; Aged; C-Peptide; Colectomy; Crohn Disease; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Tolerance Test; Humans; Insulin; Intestine, Large; Intestine, Small; Male; Middle Aged; Peptide Fragments; Postoperative Complications | 1996 |
Effects of somatostatin-28 on plasma glucose-dependent insulinotropic polypeptide and serum insulin concentrations.
Topics: Animals; Blood Glucose; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Infusions, Intravenous; Insulin; Insulin Secretion; Peptide Fragments; Sheep; Somatostatin; Somatostatin-28 | 1995 |
Glucagon-like peptide-1(7-36)amide induces the release of aspartic acid and glutamine by the ventromedial hypothalamus of the conscious rat.
Topics: Animals; Aspartic Acid; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glutamine; Hypothalamus, Middle; Male; Microdialysis; Neurotransmitter Agents; Peptide Fragments; Rats; Rats, Wistar | 1995 |
Glucagon-like peptide-1(7-36)amide enhances insulin-stimulated glucose uptake and decreases intracellular cAMP content in isolated rat adipocytes.
Topics: 1-Methyl-3-isobutylxanthine; Adipocytes; Animals; Colforsin; Cyclic AMP; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Glucose; Insulin; Male; Peptide Fragments; Peptides; Phosphodiesterase Inhibitors; Rats | 1996 |
Increased ileal proglucagon expression after jejunectomy is not suppressed by inhibition of bowel growth.
Topics: Adaptation, Physiological; Animals; Blotting, Northern; Eflornithine; Enzyme Inhibitors; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Hyperplasia; Ileum; Intestinal Mucosa; Jejunum; Male; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Peptide Fragments; Proglucagon; Protein Precursors; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1996 |
The effect of some gastrointestinal peptides on pentagastrin-stimulated acid secretion and oxyntic mucosal histamine in rats.
Topics: Animals; Gastric Acid; Gastric Inhibitory Polypeptide; Gastric Mucosa; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Histamine; Histidine Decarboxylase; Male; Neurotransmitter Agents; Pentagastrin; Peptide Fragments; Rats; Rats, Wistar; Somatostatin; Vasoactive Intestinal Peptide | 1996 |
Glucagon-like peptide-1(7-36)amide increases cyclic AMP accumulation in normal islets.
Topics: Animals; Cyclic AMP; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Islets of Langerhans; Peptide Fragments; Rats; Rats, Sprague-Dawley | 1996 |
Role of prohormone convertases in the tissue-specific processing of proglucagon.
Topics: Animals; Cell Line; Chromatography, High Pressure Liquid; Cricetinae; Furin; Glicentin; Glucagon; Glucagon-Like Peptides; Kidney; Metallothionein; Mice; Peptide Fragments; Proglucagon; Promoter Regions, Genetic; Protein Precursors; Rats; Recombinant Proteins; RNA Processing, Post-Transcriptional; Subtilisins; Transfection; Tumor Cells, Cultured | 1996 |
Proglucagon processing in islet and intestinal cell lines.
Topics: Animals; Blotting, Northern; Cell Line; Cricetinae; Furin; Glicentin; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Intestinal Mucosa; Intestines; Islets of Langerhans; Mice; Oxyntomodulin; Peptide Fragments; Proglucagon; Protein Precursors; Protein Processing, Post-Translational; RNA, Messenger; Subtilisins; Transcription, Genetic | 1996 |
Insulinotropic effects of cholecystokinin, gastric inhibitory polypeptide and glucagon-like peptide-1 during perifusion of short-term cultured canine isolated islets.
Topics: Animals; Cells, Cultured; Cholecystokinin; Dogs; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Insulin; Islets of Langerhans; Peptide Fragments; Peptides; Protein Precursors | 1995 |
Induction of intestinal epithelial proliferation by glucagon-like peptide 2.
Topics: Animals; Cell Division; Glicentin; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Glucagonoma; Ileum; Immunohistochemistry; Intestinal Mucosa; Jejunum; Kinetics; Mice; Mice, Nude; Organ Size; Pancreatic Hormones; Pancreatic Neoplasms; Peptide Fragments; Peptides; Proglucagon; Proliferating Cell Nuclear Antigen; Protein Precursors; Rats; Transplantation, Heterologous | 1996 |
Effects of glucagon and glucagon-like peptide-1-(7-36) amide on C cells from rat thyroid and medullary thyroid carcinoma CA-77 cell line.
Topics: Animals; Binding, Competitive; Calcitonin; Carcinoma, Medullary; Cyclic AMP; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Peptide Fragments; Perfusion; Rats; Rats, Wistar; Thyroid Gland; Thyroid Neoplasms; Tumor Cells, Cultured | 1996 |
Effects of glucagon-like peptide-I on glucose turnover in rats.
Topics: Animals; Blood Glucose; Eating; Fasting; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Insulin; Male; Metabolic Clearance Rate; Peptide Fragments; Rats; Rats, Wistar | 1996 |
Plasma and intestinal concentrations of GIP and GLP-1 (7-36) amide during suckling and after weaning in pigs.
Topics: Animals; Animals, Suckling; Blood Glucose; Food; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Insulin; Intestinal Mucosa; Milk; Peptide Fragments; Swine; Weaning | 1995 |
Glucagon-like-peptide-1 (7-36) amide improves glucose sensitivity in beta-cells of NOD mice.
Topics: Animals; Cells, Cultured; Diabetes Mellitus, Type 2; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Mice; Mice, Inbred NOD; Mice, Mutant Strains; Pancreas; Peptide Fragments; Time Factors | 1996 |
Inositolphosphoglycans are possible mediators of the glucagon-like peptide 1 (7-36)amide action in the liver.
Topics: Animals; Cell Line, Transformed; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glycogen; Glycogen Synthase; Glycosylphosphatidylinositols; Humans; Liver; Neurotransmitter Agents; Peptide Fragments; Rats | 1996 |
The entero-insular axis in polycystic ovarian syndrome.
Topics: Adult; Blood Glucose; C-Peptide; Case-Control Studies; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Tolerance Test; Humans; Hyperinsulinism; Insulin; Neurotransmitter Agents; Peptide Fragments; Polycystic Ovary Syndrome; Proinsulin | 1996 |
Investigation of glucose-dependent insulinotropic polypeptide-(1-42) and glucagon-like peptide-1-(7-36) degradation in vitro by dipeptidyl peptidase IV using matrix-assisted laser desorption/ionization-time of flight mass spectrometry. A novel kinetic app
Topics: Animals; Dipeptidyl Peptidase 4; Enzymes; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Hydrolysis; Kinetics; Peptide Fragments; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine | 1996 |
Expression of glucagon-like peptide 1 receptor in a murine C cell line: regulation of calcitonin gene by glucagon-like peptide 1.
Topics: Animals; Base Sequence; Calcitonin; Calcitonin Gene-Related Peptide; Cell Line; DNA Primers; Gene Expression Regulation, Neoplastic; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Kinetics; Molecular Sequence Data; Oligonucleotide Probes; Peptide Fragments; Peptides; Polymerase Chain Reaction; Rats; Receptors, Glucagon; RNA, Messenger; Thyroid Neoplasms; Transcription, Genetic; Tumor Cells, Cultured | 1996 |
Secretion of the incretin hormones glucagon-like peptide-1 and gastric inhibitory polypeptide correlates with insulin secretion in normal man throughout the day.
Topics: Adult; Circadian Rhythm; Female; Gastric Inhibitory Polypeptide; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Insulin Secretion; Intestine, Small; Male; Peptide Fragments | 1996 |
Glucagon acts through its own receptors in the presence of functional glucagon-like peptide-1 receptors on hamster insulinoma.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Cell Line; Cell Membrane; Cricetinae; Cross-Linking Reagents; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Insulinoma; Islets of Langerhans; Mice; Pancreatic Neoplasms; Peptide Fragments; Peptides; Receptors, Glucagon; RNA, Messenger | 1996 |
Glucagon-like peptide-1(7-36)amide and cytoplasmic calcium in insulin producing cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Cytoplasm; Fura-2; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Insulin; Insulinoma; Islets of Langerhans; Male; Neurotransmitter Agents; Peptide Fragments; Phosphodiesterase Inhibitors; Protein Precursors; Rats; Rats, Sprague-Dawley; Sincalide; Tumor Cells, Cultured | 1996 |
Colocalization of glucagon-like peptide-1 (GLP-1) receptors, glucose transporter GLUT-2, and glucokinase mRNAs in rat hypothalamic cells: evidence for a role of GLP-1 receptor agonists as an inhibitory signal for food and water intake.
Topics: Animals; Cerebral Ventricles; Drinking Behavior; Feeding Behavior; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Glucokinase; Glucose Transporter Type 2; Hypothalamus; In Situ Hybridization; Injections, Intraventricular; Male; Monosaccharide Transport Proteins; Neurotransmitter Agents; Peptide Fragments; Peptides; Rats; Rats, Wistar; Receptors, Glucagon; RNA, Messenger; Signal Transduction; Transcription, Genetic | 1996 |
Normalization of insulin responses to glucose by overnight infusion of glucagon-like peptide 1 (7-36) amide in patients with NIDDM.
Topics: Blood Glucose; Diabetes Mellitus, Type 2; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Homeostasis; Humans; Infusions, Intravenous; Insulin; Insulin Secretion; Islets of Langerhans; Male; Middle Aged; Models, Biological; Neurotransmitter Agents; Peptide Fragments; Reference Values; Time Factors | 1996 |
Glucagon-like peptide-1(7-36) amide and glycogen synthesis in the liver.
Topics: Animals; Cells, Cultured; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Insulin; Kinetics; Liver; Liver Glycogen; Peptide Fragments; Rats | 1996 |
Central administration of GLP-1-(7-36) amide inhibits food and water intake in rats.
Topics: Animals; Behavior, Animal; Brain; Drinking; Eating; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Injections, Intraventricular; Male; Natriuresis; Peptide Fragments; Rats; Rats, Wistar | 1996 |
Central infusions of leptin and GLP-1-(7-36) amide differentially stimulate c-FLI in the rat brain.
Topics: Animals; Brain; Eating; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Immunohistochemistry; Injections, Intraventricular; Leptin; Male; Peptide Fragments; Proteins; Proto-Oncogene Proteins c-fos; Rats; Rats, Inbred Strains; Tissue Distribution | 1996 |
Gut incretin hormones in identical twins discordant for non-insulin-dependent diabetes mellitus (NIDDM)--evidence for decreased glucagon-like peptide 1 secretion during oral glucose ingestion in NIDDM twins.
Topics: Administration, Oral; Area Under Curve; Body Mass Index; Diabetes Mellitus, Type 2; Fasting; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glucose Tolerance Test; Humans; Insulin; Insulin Secretion; Intestinal Mucosa; Male; Middle Aged; Neurotransmitter Agents; Peptide Fragments; Protein Precursors; Sex Characteristics | 1996 |
The betaHC-9 pancreatic beta-cell line preserves the characteristics of progenitor mouse islets.
Topics: Animals; Arginine; Calcium; Carbachol; Cell Division; Cell Line; Glucagon-Like Peptides; Glucose; Glyburide; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; Mice; Neuropeptides; Peptides; Pituitary Adenylate Cyclase-Activating Polypeptide; Rats; Rats, Sprague-Dawley | 1996 |
The enteroinsular axis in dipeptidyl peptidase IV-negative rats.
Topics: Animals; Dipeptidyl Peptidase 4; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glucose Tolerance Test; Insulin; Insulin Secretion; Peptide Fragments; Perfusion; Rats; Rats, Inbred F344 | 1996 |
Effects of somatostatin-28 on circulating concentrations of insulin and gut hormones in sheep.
Topics: Animals; Depression, Chemical; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Insulin; Peptide Fragments; Protein Precursors; Sheep; Somatostatin; Somatostatin-28 | 1996 |
Vagal hepatopancreatic reflex effect evoked by intraportal appearance of tGLP-1.
Topics: Afferent Pathways; Animals; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Injections, Intravenous; Liver; Male; Pancreas; Peptide Fragments; Portal Vein; Protein Precursors; Rats; Rats, Wistar; Reflex; Time Factors; Vagus Nerve | 1996 |
The hepatic vagal nerve is receptive to incretin hormone glucagon-like peptide-1, but not to glucose-dependent insulinotropic polypeptide, in the portal vein.
Topics: Afferent Pathways; Animals; Electrophysiology; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Injections, Intravenous; Liver; Male; Neurotransmitter Agents; Peptide Fragments; Portal Vein; Rats; Rats, Wistar; Vagus Nerve | 1996 |
Interactions of exendin-(9-39) with the effects of glucagon-like peptide-1-(7-36) amide and of exendin-4 on arterial blood pressure and heart rate in rats.
Topics: Animals; Blood Pressure; Exenatide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Heart Rate; Male; Peptide Fragments; Peptides; Rats; Rats, Sprague-Dawley; Venoms | 1996 |
Truncated glucagon-like peptide-1 and oxyntomodulin stimulate somatostatin release from rabbit fundic D-cells in primary culture.
Topics: Animals; Cells, Cultured; Gastric Acid; Gastric Fundus; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Oxyntomodulin; Peptide Fragments; Rabbits; Somatostatin | 1996 |
Attenuated GLP-1 secretion in obesity: cause or consequence?
Topics: Adult; Case-Control Studies; Dietary Carbohydrates; Dietary Fats; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Heparin; Humans; Obesity; Peptide Fragments; Radioimmunoassay | 1996 |
Postprandial glucose-dependent insulinotropic polypeptide and insulin responses in patients with chronic pancreatitis with and without secondary diabetes.
Topics: Adult; Age Factors; Diabetes Mellitus; Digestion; Exocrine Pancreatic Insufficiency; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Male; Middle Aged; Pancreatitis; Peptide Fragments; Postprandial Period; Sex Factors | 1996 |
Glucagon-like peptide-1 and satiety.
Topics: Animals; Avoidance Learning; Eating; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Neuropeptides; Peptide Fragments; Proto-Oncogene Proteins c-fos; Rats; Saccharin; Satiety Response; Taste | 1997 |
Regulation of glycosylphosphatidylinositol-specific phospholipase D secretion from beta TC3 cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Carbachol; Cycloheximide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Immunohistochemistry; Insulin; Insulin Secretion; Insulinoma; Islets of Langerhans; Kinetics; Mice; Pancreatic Neoplasms; Peptide Fragments; Phospholipase D; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1997 |
Glucagon-like peptide-1-(9-36) amide is a major metabolite of glucagon-like peptide-1-(7-36) amide after in vivo administration to dogs, and it acts as an antagonist on the pancreatic receptor.
Topics: Animals; Chromatography, High Pressure Liquid; Cricetinae; Dogs; Enzyme-Linked Immunosorbent Assay; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Humans; Pancreas; Peptide Fragments; Radioimmunoassay; Receptors, Glucagon | 1996 |
Incretin hormone expression in the gut of diabetic mice and rats.
Topics: Animals; Blotting, Northern; Colon; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Disease Models, Animal; Gastric Inhibitory Polypeptide; Gene Expression; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Intestinal Mucosa; Intestine, Small; Intestines; Mice; Mice, Inbred NOD; Peptide Fragments; Proglucagon; Protein Precursors; Rats; Rats, Zucker; Rectum; RNA, Messenger; Tissue Distribution | 1997 |
Protein kinase A-dependent stimulation of exocytosis in mouse pancreatic beta-cells by glucose-dependent insulinotropic polypeptide.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Cell Membrane; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Electric Conductivity; Enzyme Inhibitors; Exocytosis; Gastric Inhibitory Polypeptide; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Islets of Langerhans; Membrane Potentials; Mice; Mice, Inbred Strains; Peptide Fragments; Phosphodiesterase Inhibitors; Tetradecanoylphorbol Acetate; Thionucleotides | 1997 |
Glucagon-like peptide I and glucose-dependent insulinotropic polypeptide stimulate Ca2+-induced secretion in rat alpha-cells by a protein kinase A-mediated mechanism.
Topics: Animals; Calcium; Calcium Channels; Cyclic AMP-Dependent Protein Kinases; Exocytosis; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Islets of Langerhans; Peptide Fragments; Rats; Somatostatin | 1997 |
Exendin-4 agonist and exendin(9-39)amide antagonist of the GLP-1(7-36)amide effects in liver and muscle.
Topics: Animals; Cyclic AMP; Energy Metabolism; Enzyme Activation; Exenatide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glycogen; Glycogen Synthase; Insulin; Liver; Muscle, Skeletal; Peptide Fragments; Peptides; Phosphorylase a; Rats; Rats, Wistar; Venoms | 1997 |
Helicobacter pylori infection accelerates gene expression of glicentin in the gastric mucosa. Its association with intestinal metaplasia of the stomach.
Topics: Adult; Aged; DNA Primers; Duodenum; Endoscopy, Digestive System; Esophagus; Female; Gastric Mucosa; Gene Expression; Glicentin; Glucagon; Glucagon-Like Peptides; Helicobacter Infections; Helicobacter pylori; Humans; Male; Metaplasia; Middle Aged; Peptide Fragments; Polymerase Chain Reaction; Protein Precursors; Retrospective Studies; RNA, Messenger | 1997 |
The inhibitory effect of glucagon-like peptide-1 (GLP-1) 7-36 amide on gastric acid secretion in humans depends on an intact vagal innervation.
Topics: Adult; Aged; Blood Glucose; Duodenal Ulcer; Female; Gastric Acid; Gastric Mucosa; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Male; Middle Aged; Pentagastrin; Peptide Fragments; Vagotomy | 1997 |
Trophic effects of glicentin on rat small-intestinal mucosa in vivo and in vitro.
Topics: Alkaline Phosphatase; Animals; Binding Sites; Body Weight; Cell Count; Cell Line; DNA; Glicentin; Glucagon; Glucagon-Like Peptides; Intestinal Mucosa; Intestine, Small; Male; Peptide Fragments; Protein Precursors; Rats; Rats, Wistar | 1997 |
Cloning and characterization of the 5' flanking sequences (promoter region) of the human GLP-1 receptor gene.
Topics: Base Sequence; Cloning, Molecular; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Humans; Insulinoma; Molecular Sequence Data; Peptide Fragments; Promoter Regions, Genetic; Receptors, Glucagon; Sequence Analysis, DNA; Transcription, Genetic; Tumor Cells, Cultured | 1997 |
Endoproteolysis of glucagon-like peptide (GLP)-1 (7-36) amide by ectopeptidases in RINm5F cells.
Topics: Amino Acid Sequence; Animals; Cell Membrane; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Hydrolysis; Insulinoma; Peptide Fragments; Peptide Hydrolases; Rats; Tumor Cells, Cultured | 1997 |
Regulation of the biological activity of glucagon-like peptide 2 in vivo by dipeptidyl peptidase IV.
Topics: Animals; Biotechnology; Dipeptidyl Peptidase 4; Glucagon; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Humans; In Vitro Techniques; Intestine, Small; Mice; Peptides; Protein Engineering; Rats; Rats, Inbred F344; Recombinant Proteins | 1997 |
Preserved GLP-I effects on glycogen synthase a activity and glucose metabolism in isolated hepatocytes and skeletal muscle from diabetic rats.
Topics: Animals; Animals, Newborn; Carbon Radioisotopes; Cells, Cultured; Cohort Studies; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucagon-Like Peptides; Glucose; Glycogen Synthase; Insulin; Liver; Muscle, Skeletal; Pancreatic Hormones; Peptides; Phosphorylases; Rats; Rats, Wistar | 1997 |
Multisite regulation of insulin secretion by cAMP-increasing agonists: evidence that glucagon-like peptide 1 and glucagon act via distinct receptors.
Topics: Animals; Calcium; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Electrophysiology; Enzyme Activation; Exocytosis; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Mice; Mice, Inbred Strains; Neurotransmitter Agents; Peptide Fragments; Peptides; Receptors, Cell Surface | 1997 |
Cardiovascular and pancreatic endocrine responses to glucagon-like peptide-1(7-36) amide in the conscious calf.
Topics: Amino Acids; Animals; Blood Glucose; Blood Pressure; Cattle; Enzyme Inhibitors; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Heart Rate; Insulin; Insulin Secretion; Islets of Langerhans; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroprusside; Pancreatic Polypeptide; Peptide Fragments | 1997 |
High potency antagonists of the pancreatic glucagon-like peptide-1 receptor.
Topics: Amino Acid Sequence; Animals; Binding, Competitive; CHO Cells; Cricetinae; Cyclic AMP; Exenatide; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Molecular Sequence Data; Peptide Fragments; Peptides; Rats; Receptors, Glucagon; Recombinant Fusion Proteins; Sequence Deletion; Structure-Activity Relationship; Transfection; Venoms | 1997 |
GLP-1 (7-36) amide activates L-type Ca2+ channels of pancreatic B-cells through c-AMP signaling.
Topics: Action Potentials; Animals; Barium; Calcium Channels; Cyclic AMP; Electric Conductivity; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Islets of Langerhans; Male; Peptide Fragments; Rats; Signal Transduction | 1997 |
Identification of amidated forms of GLP-1 in rat tissues using a highly sensitive radioimmunoassay.
Topics: Animals; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Hypothalamus; Ileum; Immune Sera; Intubation, Gastrointestinal; Male; Organ Specificity; Pancreas; Peptide Fragments; Peptides; Rabbits; Radioimmunoassay; Rats; Rats, Wistar | 1997 |
Novel signal transduction and peptide specificity of glucagon-like peptide receptor in 3T3-L1 adipocytes.
Topics: 3T3 Cells; Adipocytes; Animals; Binding, Competitive; Calcium; CHO Cells; Cricetinae; Cyclic AMP; Exenatide; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Lipolysis; Mice; Peptide Fragments; Peptides; Receptors, Gastrointestinal Hormone; Receptors, Glucagon; Signal Transduction; Venoms | 1997 |
Role of the prohormone convertase PC2 in the processing of proglucagon to glucagon.
Topics: Animals; Carboxypeptidase H; Carboxypeptidases; Cells, Cultured; Glucagon; Glucagon-Like Peptides; Immunoblotting; Oxyntomodulin; Pituitary Gland; Proglucagon; Proprotein Convertase 2; Protein Precursors; Rats; Subtilisins; Transfection | 1997 |
Effect of glicentin, oxyntomodulin and related peptides on isolated gastric smooth muscle cells.
Topics: Animals; Cell Separation; Cell Size; Dose-Response Relationship, Drug; Glicentin; Glucagon; Glucagon-Like Peptides; Humans; Male; Muscle Contraction; Muscle, Smooth; Oxyntomodulin; Peptide Fragments; Protein Precursors; Rabbits; Stomach; Time Factors | 1997 |
Central administration of glucagon-like peptide-1 activates hypothalamic neuroendocrine neurons in the rat.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Blood Glucose; Corticosterone; Corticotropin-Releasing Hormone; Gene Expression Regulation; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Hypothalamo-Hypophyseal System; Hypothalamus; Immunohistochemistry; Injections, Intraventricular; Male; Neurons; Oxytocin; Paraventricular Hypothalamic Nucleus; Peptide Fragments; Phenotype; Pituitary-Adrenal System; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Supraoptic Nucleus; Time Factors; Vasopressins | 1997 |
Decreased intake of a liquid diet in nonfood-deprived rats following intra-PVN injections of GLP-1 (7-36) amide.
Topics: Adrenergic alpha-Agonists; Animals; Depression, Chemical; Diet; Eating; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Male; Microinjections; Neurotransmitter Agents; Norepinephrine; Paraventricular Hypothalamic Nucleus; Peptide Fragments; Rats; Rats, Sprague-Dawley | 1997 |
GLP-I(7-36) amide augments Ba2+ current through L-type Ca2+ channel of rat pancreatic beta-cell in a cAMP-dependent manner.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Barium; Bucladesine; Calcium Channels; Calcium Channels, L-Type; Cells, Cultured; Cyclic AMP; Electric Stimulation; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Islets of Langerhans; Kinetics; Membrane Potentials; Peptide Fragments; Rats; Thionucleotides; Tolbutamide | 1997 |
Intestinal growth is associated with elevated levels of glucagon-like peptide 2 in diabetic rats.
Topics: Animals; Diabetes Mellitus, Experimental; Gastrointestinal Hormones; Glicentin; Glucagon; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Insulin; Intestine, Small; Male; Organ Size; Organ Specificity; Oxyntomodulin; Peptide Fragments; Peptides; Proglucagon; Protein Precursors; Rats; Rats, Wistar; Time Factors | 1997 |
Activation of the hepatic glycine cleavage enzyme system by glucagon and glucagon-related peptides.
Topics: Animals; Glicentin; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glycine; In Vitro Techniques; Liver; Male; Oxyntomodulin; Peptide Fragments; Peptides; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptors, Glucagon | 1997 |
GLP-1 (7-36) amide: effects on glucose transport and metabolism in rat adipose tissue.
Topics: Adipose Tissue; Animals; Biological Transport; Deoxyglucose; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glycogen; Insulin; Lipids; Male; Oxidation-Reduction; Peptide Fragments; Rats; Rats, Wistar | 1997 |
Characterization of dopuin, a polypeptide with special residue distributions.
Topics: Amino Acid Sequence; Animals; Chromatography, High Pressure Liquid; Disulfides; Gastrointestinal Hormones; Glucagon-Like Peptides; Humans; Insulin; Insulin Secretion; Intestine, Small; Islets of Langerhans; Liver; Male; Molecular Sequence Data; Molecular Weight; Peptide Fragments; Peptides; Rats; Rats, Wistar; Spleen; Swine; Vimentin | 1997 |
Methods for the investigation of neuropeptide catabolism and stability in vitro.
Topics: Animals; Blood Physiological Phenomena; Brain; Cell Line; Cells, Cultured; Chromatography, High Pressure Liquid; Drug Stability; Enkephalin, Leucine; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Microglia; Neuropeptides; Peptide Fragments; Rats; Rats, Wistar; Somatostatin | 1997 |
Regulation of growth hormone secretion in lactating sheep.
Topics: Animals; Eating; Fasting; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Growth Hormone; Homeostasis; Lactation; Peptide Fragments; Sheep | 1997 |
Melanocortin receptors in leptin effects.
Topics: Animals; Anorexia; Body Weight; Eating; Glucagon-Like Peptides; Leptin; Male; Melanocyte-Stimulating Hormones; Paraventricular Hypothalamic Nucleus; Peptides; Proteins; Proto-Oncogene Proteins c-fos; Rats; Receptors, Corticotropin; Receptors, Melanocortin; Signal Transduction | 1997 |
Effects of non-glycated and glycated glucagon-like peptide-1(7-36) amide on glucose metabolism in isolated mouse abdominal muscle.
Topics: Abdominal Muscles; Animals; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glycosylation; In Vitro Techniques; Insulin; Male; Mice; Oxidation-Reduction; Peptide Fragments; Peptides | 1997 |
Elevated post-prandial gastric inhibitory polypeptide concentrations in hypertriglyceridaemic subjects.
Topics: Adult; Blood Glucose; Cholesterol; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Hyperinsulinism; Hypertriglyceridemia; Male; Middle Aged; Peptide Fragments; Postprandial Period; Statistics, Nonparametric | 1997 |
Role of the prohormone convertase PC3 in the processing of proglucagon to glucagon-like peptide 1.
Topics: Animals; Aspartic Acid Endopeptidases; Cells, Cultured; Glicentin; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Kinetics; Mice; Oxyntomodulin; Peptide Fragments; Proglucagon; Proprotein Convertases; Protein Precursors; Rats; Recombinant Proteins; Tumor Cells, Cultured | 1997 |
Glucagon-like peptide-1(7-36)-amide confers glucose sensitivity to previously glucose-incompetent beta-cells in diabetic rats: in vivo and in vitro studies.
Topics: Animals; Culture Techniques; Cyclic AMP; Diabetes Mellitus, Experimental; DNA; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glucose Tolerance Test; Insulin; Insulin Secretion; Islets of Langerhans; Male; Neurotransmitter Agents; Peptide Fragments; Perfusion; Rats; Rats, Wistar | 1997 |
Glucagon-like peptide 1 (7-36) amide stimulates exocytosis in human pancreatic beta-cells by both proximal and distal regulatory steps in stimulus-secretion coupling.
Topics: Adult; Calcium; Calcium Channels; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Exocytosis; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Islets of Langerhans; Male; Membrane Potentials; Middle Aged; Neurotransmitter Agents; Peptide Fragments; Potassium Channels; Somatostatin | 1998 |
Dual glucagon recognition by pancreatic beta-cells via glucagon and glucagon-like peptide 1 receptors.
Topics: Animals; Cells, Cultured; Cyclic AMP; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Insulin; Iodine Radioisotopes; Islets of Langerhans; Liver; Male; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptors, Glucagon | 1998 |
Glucagon-like peptide-1-(7-36) amide and peptide YY mediate intraduodenal fat-induced inhibition of acid secretion in dogs.
Topics: Animals; Benzodiazepinones; Devazepide; Dogs; Duodenum; Fats; Gastric Acid; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Peptide Fragments; Peptide YY; Protein Precursors | 1998 |
PVN infusion of GLP-1-(7-36) amide suppresses feeding but does not induce aversion or alter locomotion in rats.
Topics: Animals; Avoidance Learning; Cerebral Ventricles; Drinking Behavior; Feeding Behavior; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Infusions, Parenteral; Male; Motor Activity; Paraventricular Hypothalamic Nucleus; Peptide Fragments; Rats; Rats, Sprague-Dawley; Stereotaxic Techniques; Stereotyped Behavior; Time Factors | 1998 |
Proglucagon processing in an islet cell line: effects of PC1 overexpression and PC2 depletion.
Topics: Animals; Aspartic Acid Endopeptidases; Cell Line; DNA, Antisense; Gene Expression; Glicentin; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Islets of Langerhans; Mice; Oxyntomodulin; Peptide Fragments; Peptides; Proglucagon; Proprotein Convertase 1; Proprotein Convertase 2; Proprotein Convertases; Protein Precursors; RNA, Messenger; Subtilisins; Transfection | 1998 |
Dipeptidyl peptidase IV resistant analogues of glucagon-like peptide-1 which have extended metabolic stability and improved biological activity.
Topics: Animals; Cross Reactions; Dipeptidyl Peptidase 4; Drug Stability; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; In Vitro Techniques; Insulin; Insulin Secretion; Pancreas; Peptide Fragments; Perfusion; Protein Binding; Protein Precursors; Receptors, Glucagon; Swine | 1998 |
The human glucagon-like peptide-1 (GLP-1) receptor. Cloning and functional expression.
Topics: Amino Acid Sequence; Animals; Binding, Competitive; Calcium; Cloning, Molecular; COS Cells; Cyclic AMP; Diabetes Mellitus, Type 2; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Humans; Kinetics; Molecular Sequence Data; Peptide Fragments; Peptides; Polymerase Chain Reaction; Protein Precursors; Rats; Receptors, Glucagon; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Transfection | 1997 |
Cyclic AMP, a mediator of GLP-1, acts in concert with glucose and tolbutamide to increase cytosolic Ca2+ in pancreatic B-cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Cytosol; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Islets of Langerhans; Peptide Fragments; Potassium Chloride; Rats; Rats, Wistar; Tolbutamide | 1997 |
Effect of chronic central administration of glucagon-like peptide-1 (7-36) amide on food consumption and body weight in normal and obese rats.
Topics: Animals; Body Weight; Eating; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Injections, Intraventricular; Insulinoma; Male; Neurotransmitter Agents; Obesity; Pancreatic Neoplasms; Peptide Fragments; Rats; Rats, Sprague-Dawley; Rats, Zucker; Receptors, Glucagon; Tumor Cells, Cultured | 1998 |
Molecular cloning of the helodermin and exendin-4 cDNAs in the lizard. Relationship to vasoactive intestinal polypeptide/pituitary adenylate cyclase activating polypeptide and glucagon-like peptide 1 and evidence against the existence of mammalian homolog
Topics: Amino Acid Sequence; Animals; Base Sequence; Chickens; Cloning, Molecular; DNA Primers; DNA, Complementary; Exenatide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Intercellular Signaling Peptides and Proteins; Lizards; Mammals; Molecular Sequence Data; Neuropeptides; Peptide Fragments; Peptides; Pituitary Adenylate Cyclase-Activating Polypeptide; Polymerase Chain Reaction; Protein Precursors; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Trout; Vasoactive Intestinal Peptide; Venoms | 1998 |
Glucagon-like peptide-1-(7-36)amide increases pulmonary surfactant secretion through a cyclic adenosine 3',5'-monophosphate-dependent protein kinase mechanism in rat type II pneumocytes.
Topics: Adrenergic beta-Agonists; Animals; Calcimycin; Calcium-Transporting ATPases; Cells, Cultured; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Kinetics; Lung; Male; Peptide Fragments; Phosphatidylcholines; Pulmonary Surfactants; Rats; Rats, Wistar; Terbutaline; Tetradecanoylphorbol Acetate; Thapsigargin | 1998 |
Glucagon-like peptide 1(7-36) amide's central inhibition of feeding and peripheral inhibition of drinking are abolished by neonatal monosodium glutamate treatment.
Topics: Angiotensin II; Animals; Animals, Newborn; Arcuate Nucleus of Hypothalamus; Avoidance Learning; Blood Glucose; Blood-Brain Barrier; Brain; Cerebral Ventricles; Drinking; Eating; Food Additives; Food Deprivation; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Male; Neuropeptide Y; Peptide Fragments; Rats; Rats, Wistar; Sodium Glutamate; Subfornical Organ; Taste | 1998 |
Effects of glucagon-like peptide 1 (7-36 amide) on glucose kinetics during somatostatin-induced suppression of insulin secretion in healthy men.
Topics: Adult; Blood Glucose; C-Peptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Clamp Technique; Humans; Hyperglycemia; Infusions, Intravenous; Insulin; Insulin Secretion; Kinetics; Male; Peptide Fragments; Proinsulin; Somatostatin | 1998 |
Inositolphosphoglycans possibly mediate the effects of glucagon-like peptide-1(7-36)amide on rat liver and adipose tissue.
Topics: Adipocytes; Adipose Tissue; Animals; Cells, Cultured; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glycosylphosphatidylinositols; Liver; Male; Peptide Fragments; Rats; Rats, Wistar | 1998 |
Plasma glucagon-like peptide-1 (7-36) amide (GLP-1) response to liquid phase, solid phase, and meals of differing lipid composition.
Topics: Adult; Beverages; Blood Glucose; Dietary Fats; Dietary Fats, Unsaturated; Energy Intake; Female; Food; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Kinetics; Male; Peptide Fragments | 1998 |
Insulinotropic hormone glucagon-like peptide-1-(7-37) appears not to augment insulin-mediated glucose uptake in young men during euglycemia.
Topics: Adrenocorticotropic Hormone; Adult; Blood Glucose; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Clamp Technique; Humans; Hydrocortisone; Hypoglycemic Agents; Insulin; Insulin Secretion; Male; Peptide Fragments; Peptides; Reference Values; Secretory Rate; Somatostatin | 1998 |
The inhibitory effect of glucagon-like peptide-1 (7-36)amide on antral motility is antagonized by its N-terminally truncated primary metabolite GLP-1 (9-36)amide.
Topics: Animals; Dose-Response Relationship, Drug; Gastrointestinal Hormones; Gastrointestinal Motility; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Hypoglycemia; Peptide Fragments; Peptides; Pyloric Antrum; Swine | 1998 |
Systemic short-chain fatty acids rapidly alter gastrointestinal structure, function, and expression of early response genes.
Topics: Animals; Blotting, Northern; Blotting, Western; Digestive System; Fatty Acids, Volatile; Gastrointestinal Hormones; Gene Expression; Glucagon; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Intestinal Mucosa; Male; Parenteral Nutrition, Total; Peptides; Proglucagon; Protein Precursors; Proto-Oncogenes; Random Allocation; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1998 |
Changes in the concentrations of glucagon-like peptide-1(7-36)amide and gastric inhibitory polypeptide during the lactation cycle in goats.
Topics: Animals; Blood Glucose; Fatty Acids, Nonesterified; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Goats; Insulin; Lactation; Peptide Fragments; Pregnancy; Time Factors | 1998 |
Oxyntomodulin reduces hydromineral transport through rat small intestine.
Topics: Animals; Biological Transport; Body Water; Chlorides; Glicentin; Glucagon; Glucagon-Like Peptides; In Vitro Techniques; Intestinal Absorption; Intestinal Secretions; Intestine, Small; Male; Osmolar Concentration; Oxyntomodulin; Peptide Fragments; Protein Precursors; Rats; Rats, Wistar; Sodium | 1998 |
Central infusion of glucagon-like peptide-1-(7-36) amide (GLP-1) receptor antagonist attenuates lithium chloride-induced c-Fos induction in rat brainstem.
Topics: Animals; Brain Stem; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Guinea Pigs; Infusions, Parenteral; Injections, Intraperitoneal; Injections, Intraventricular; Insulin; Insulin Secretion; Insulinoma; Lithium Chloride; Male; Neurons; Peptide Fragments; Proto-Oncogene Proteins c-fos; Rats; Rats, Long-Evans; Receptors, Glucagon; Signal Transduction; Tumor Cells, Cultured | 1998 |
GLP-1 receptors in golden Syrian hamster islets: identification and functional characterization.
Topics: Animals; Blotting, Northern; Blotting, Western; Cricetinae; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Humans; Insulin; Islets of Langerhans; Mesocricetus; Peptide Fragments; Peptides; Rats; Receptors, Glucagon | 1998 |
Effects of glucagon-like peptide-1 (7-36)amide on insulin stimulated rat skeletal muscle glucose transport.
Topics: Animals; Biological Transport; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Hypoglycemic Agents; In Vitro Techniques; Insulin; Male; Muscle, Skeletal; Peptide Fragments; Rats; Rats, Wistar | 1998 |
Intracerebroventricular glucagon-like peptide-1 (7-36) amide inhibits sham feeding in rats without eliciting satiety.
Topics: Animals; Dietary Sucrose; Feeding Behavior; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Injections, Intraventricular; Male; Peptide Fragments; Rats; Rats, Sprague-Dawley; Satiety Response | 1998 |
Glucagon- and NPY-related peptide-immunoreactive cells in the gut of sea bass (Dicentrarchus labrax L.): a light and electron microscopic study.
Topics: Animals; Bass; Fluorescent Antibody Technique; Glicentin; Glucagon; Glucagon-Like Peptides; Immunoenzyme Techniques; Intestines; Microscopy, Electron; Microscopy, Immunoelectron; Neuropeptide Y; Peptide Fragments; Protein Precursors; Stomach | 1998 |
Effects of various N-terminal fragments of glucagon-like peptide-1(7-36) on food intake in the neonatal chick.
Topics: Amino Acid Sequence; Analysis of Variance; Animals; Animals, Newborn; Chickens; Feeding Behavior; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Injections, Intraventricular; Male; Molecular Sequence Data; Peptide Fragments; Sequence Homology, Amino Acid | 1998 |
Functional interactions between melanin-concentrating hormone, neuropeptide Y, and anorectic neuropeptides in the rat hypothalamus.
Topics: alpha-MSH; Animals; Appetite Depressants; Appetite Stimulants; Drug Interactions; Eating; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Hypothalamic Hormones; Hypothalamus; Injections, Intraventricular; Kinetics; Male; Melanins; Neuropeptide Y; Neurotensin; Peptide Fragments; Pituitary Hormones; Rats; Rats, Sprague-Dawley | 1998 |
Glycation of glucagon-like peptide-1(7-36)amide: characterization and impaired action on rat insulin secreting cells.
Topics: Amino Acid Sequence; Animals; Antibody Specificity; Cell Line; Chromatography, High Pressure Liquid; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glycosylation; Insulin; Insulin Secretion; Intestine, Small; Islets of Langerhans; Mice; Molecular Sequence Data; Peptide Fragments; Radioimmunoassay; Rats; Sequence Analysis; Structure-Activity Relationship | 1998 |
A synthetic glucagon-like peptide-1 analog with improved plasma stability.
Topics: Animals; Chromatography, High Pressure Liquid; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Glucose; Humans; Insulin; Insulin Secretion; Male; Peptide Fragments; Protein Precursors; Rats; Rats, Wistar; Receptors, Glucagon; Time Factors; Tumor Cells, Cultured | 1998 |
Enteric glucagon 37 rather than pancreatic glucagon 29 stimulates glucose absorption in rat intestine.
Topics: Absorption; Animals; Bucladesine; Cyclic AMP; Dose-Response Relationship, Drug; Glucagon; Glucagon-Like Peptides; Glucose; In Vitro Techniques; Intestine, Small; Liver; Male; Membrane Glycoproteins; Monosaccharide Transport Proteins; Pancreas; Peptides; Rats; Rats, Wistar; Sodium-Glucose Transporter 1 | 1998 |
Amidated and non-amidated glucagon-like peptide-1 (GLP-1): non-pancreatic effects (cephalic phase acid secretion) and stability in plasma in humans.
Topics: Adult; Bacitracin; Female; Gastric Acid; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Male; Middle Aged; Oligopeptides; Peptide Fragments; Protein Precursors; Stomach | 1998 |
Glucagon-like peptide-1 inhibits gastropancreatic function by inhibiting central parasympathetic outflow.
Topics: Animals; Bicarbonates; Blood Glucose; Gastric Acid; Gastrins; Gastrointestinal Motility; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Islets of Langerhans; Muscle Contraction; Muscle, Smooth; Neurotransmitter Agents; Pancreas; Pancreatic Juice; Pancreatic Polypeptide; Parasympathetic Nervous System; Peptide Fragments; Protein Precursors; Stomach; Swine; Vagotomy; Vagus Nerve | 1998 |
The ageing entero-insular axis.
Topics: Acetaminophen; Adult; Aged; Aging; Blood Glucose; Body Mass Index; Body Weight; Diabetes Mellitus, Type 2; Dietary Carbohydrates; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Intolerance; Humans; Insulin; Insulin Secretion; Peptide Fragments; Postmenopause; Premenopause; Risk Factors | 1998 |
Coexpression of glucagon-like peptide-1 (GLP-1) receptor, vasopressin, and oxytocin mRNAs in neurons of the rat hypothalamic supraoptic and paraventricular nuclei: effect of GLP-1(7-36)amide on vasopressin and oxytocin release.
Topics: Animals; Brain Chemistry; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; In Situ Hybridization; Male; Neurons; Oxytocin; Paraventricular Hypothalamic Nucleus; Peptide Fragments; Pituitary Gland; Protein Precursors; Rats; Rats, Wistar; RNA, Messenger; Supraoptic Nucleus; Vasopressins | 1999 |
Glicentin and oxyntomodulin modulate both the phosphoinositide and cyclic adenosine monophosphate signaling pathways in gastric myocytes.
Topics: Animals; Calcium; Carbachol; Colforsin; Cyclic AMP; Glicentin; Glucagon; Glucagon-Like Peptides; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Muscle Contraction; Muscle, Smooth; Oxyntomodulin; Peptide Fragments; Pertussis Toxin; Phosphatidylinositols; Protein Precursors; Pyloric Antrum; Rabbits; Signal Transduction; Type C Phospholipases; Virulence Factors, Bordetella | 1999 |
Repeated intracerebroventricular administration of glucagon-like peptide-1-(7-36) amide or exendin-(9-39) alters body weight in the rat.
Topics: Animals; Body Weight; Energy Intake; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Injections, Intraventricular; Male; Neurotransmitter Agents; Peptide Fragments; Rats; Rats, Wistar | 1999 |
Basal cell carcinoma development is associated with induction of the expression of the transcription factor Gli-1.
Topics: Carcinoma, Basal Cell; Cell Transformation, Neoplastic; Gene Expression; Glucagon-Like Peptides; Humans; In Situ Hybridization; Neoplasm Proteins; Peptides; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Skin Neoplasms | 1998 |
Structure-function analysis of a series of glucagon-like peptide-1 analogs.
Topics: Amino Acid Sequence; Cell Line; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Peptide Fragments; Peptides; Protein Conformation; Protein Precursors; Structure-Activity Relationship | 1998 |
Oral triacylglycerols regulate plasma glucagon-like peptide-1(7-36) and insulin levels in normal and especially in obese rats.
Topics: Administration, Oral; Animals; Blood Glucose; Corn Oil; Fatty Acids; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Tolerance Test; Glycerol; Insulin; Intubation, Gastrointestinal; Obesity; Peptide Fragments; Rats; Rats, Wistar; Reference Values; Triglycerides; Veins | 1999 |
Miniglucagon: a local regulator of islet physiology.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channels; Calcium Channels, L-Type; Cell Line; Cell Membrane; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glyburide; Homeostasis; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Membrane Potentials; Peptide Fragments; Peptides | 1998 |
A target cell to oxyntomodulin and glicentin: the antral smooth muscle cell.
Topics: Animals; Cell Membrane Permeability; Cyclic AMP; Glicentin; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Muscle Contraction; Muscle, Smooth; Oxyntomodulin; Peptide Fragments; Peptides; Protein Precursors; Pyloric Antrum; Rabbits; Stomach; Thionucleotides; Vasoactive Intestinal Peptide | 1998 |
Effect of rat glicentin on intestinal adaptation in small intestine-resected rats.
Topics: Acclimatization; Amine Oxidase (Copper-Containing); Anastomosis, Surgical; Animals; DNA; Duodenum; Glicentin; Glucagon; Glucagon-Like Peptides; Ileum; Intestinal Mucosa; Intestine, Small; Male; Peptide Fragments; Peptide YY; Protein Precursors; Proteins; Rats; Rats, Wistar; Recombinant Proteins | 1998 |
Plasma glicentin in diabetic and gastrectomized patients.
Topics: Blood Glucose; Diabetes Mellitus; Gastrectomy; Glicentin; Glucagon; Glucagon-Like Peptides; Humans; Insulin; Peptide Fragments; Protein Precursors | 1999 |
The relative contribution of insulin secretory capacity, insulin action, and incretins to metabolic control after islet transplantation in dogs.
Topics: Animals; Dogs; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glucose Tolerance Test; Insulin; Insulin Secretion; Islets of Langerhans; Islets of Langerhans Transplantation; Peptide Fragments | 1999 |
Characterization of a novel, non-peptidyl antagonist of the human glucagon receptor.
Topics: Adenylyl Cyclases; Animals; Cations, Divalent; CHO Cells; Cricetinae; Enzyme Activation; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Hormone Antagonists; Humans; Molecular Structure; Mutation; Peptides; Protein Binding; Pyridines; Pyrroles; Receptors, Glucagon | 1999 |
Inhibition of carbohydrate-mediated glucagon-like peptide-1 (7-36)amide secretion by circulating non-esterified fatty acids.
Topics: Adult; Analysis of Variance; Area Under Curve; Case-Control Studies; Dietary Carbohydrates; Fatty Acids, Nonesterified; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Tolerance Test; Heparin; Humans; Insulin; Models, Biological; Neurotransmitter Agents; Obesity; Peptide Fragments; Postprandial Period; Pyrazines; Triglycerides | 1999 |
Glucose-dependent stimulatory effect of glucagon-like peptide 1(7-36) amide on the electrical activity of pancreatic beta-cells recorded in vivo.
Topics: Animals; Blood Glucose; Electrophysiology; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Hypoglycemic Agents; Insulin; Insulin Secretion; Islets of Langerhans; Mice; Osmolar Concentration; Peptide Fragments; Tolbutamide | 1999 |
Insulin secretion and intestinal peptides during lactation in sheep.
Topics: Animals; Blood Glucose; Female; Gastric Inhibitory Polypeptide; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Insulin; Insulin Secretion; Lactation; Peptide Fragments; Sheep; Somatostatin; Somatostatin-28 | 1999 |
The influence of the colon on postprandial glucagon-like peptide 1 (7-36) amide concentration in man.
Topics: Analysis of Variance; Blood Glucose; Case-Control Studies; Colitis, Ulcerative; Colon; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Ileostomy; Insulin; Male; Middle Aged; Neurotransmitter Agents; Peptide Fragments; Postprandial Period | 1999 |
Miniglucagon (glucagon 19-29), a potent and efficient inhibitor of secretagogue-induced insulin release through a Ca2+ pathway.
Topics: Calcium; Calcium Channels; Cell Line; Cholinergic Agonists; Cyclic AMP; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Insulin; Insulin Antagonists; Insulin Secretion; Ion Transport; Islets of Langerhans; Membrane Potentials; Peptide Fragments; Peptides; Pertussis Toxin; Virulence Factors, Bordetella | 1999 |
Effect of large bowel fermentation on insulin, glucose, free fatty acids, and glucagon-like peptide 1 (7-36) amide in patients with coronary heart disease.
Topics: Aged; Blood Glucose; Coronary Disease; Fatty Acids, Nonesterified; Fermentation; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Intestinal Absorption; Intestine, Large; Lactulose; Male; Middle Aged; Peptide Fragments; Risk Factors | 1999 |
Gastrointestinal responses to a panel of lectins in rats maintained on total parenteral nutrition.
Topics: Animals; Cell Division; Cholecystokinin; Colon; Digestive System; Digestive System Physiological Phenomena; Gastrins; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Insulin; Intestine, Small; Lectins; Male; Organ Size; Pancreas; Parenteral Nutrition, Total; Peanut Agglutinin; Peptide Fragments; Phytohemagglutinins; Protein Precursors; Rats; Rats, Sprague-Dawley; Stomach | 1999 |
Effect of GIP and GLP-1 antagonists on insulin release in the rat.
Topics: Absorption; Animals; Blood Glucose; Dose-Response Relationship, Drug; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Insulin; Peptide Fragments; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptors, Gastrointestinal Hormone | 1999 |
In vivo dynamic distribution of 131I-glucagon-like peptide-1 (7-36) amide in the rat studied by gamma camera.
Topics: Animals; Brain; Gamma Cameras; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Iodine Radioisotopes; Male; Metabolic Clearance Rate; Peptide Fragments; Rats; Rats, Sprague-Dawley; Tissue Distribution | 1999 |
Biochemical basis of oligofructose-induced hypolipidemia in animal models.
Topics: Animals; Blood Glucose; Dietary Fiber; Fatty Acids; Gene Expression Regulation, Enzymologic; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Insulin; Lipoproteins; Liver; Male; Neurotransmitter Agents; Oligosaccharides; Peptide Fragments; Rats; Rats, Wistar; Triglycerides | 1999 |
Comparison of the postprandial release of peptide YY and proglucagon-derived peptides in the rat.
Topics: Animals; Fatty Acids; Food; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Hexamethonium; Kinetics; Male; Oleic Acid; Oxyntomodulin; Peptide Fragments; Peptide YY; Proglucagon; Protein Precursors; Rats; Rats, Wistar | 1999 |
Short bowel, short answer?
Topics: Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Humans; Peptides; Short Bowel Syndrome | 1999 |
[Inhibition of incretin degradation--a new therapy principle for treatment of type 2 diabetes?].
Topics: Administration, Oral; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Enzyme Inhibitors; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Hypoglycemic Agents; Isoleucine; Peptide Fragments; Rats; Rats, Zucker; Thiazoles | 1999 |
Glucagon-like peptide-1 modulates neuronal activity in the rat's hippocampus.
Topics: Animals; Aspartic Acid; Cerebral Cortex; Electroencephalography; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Glutamic Acid; Glutamine; Hippocampus; Injections, Intraventricular; Male; Neurons; Peptide Fragments; Peptides; Protein Precursors; Rats; Rats, Wistar; Receptors, Glucagon; Stimulation, Chemical; Ventromedial Hypothalamic Nucleus | 1999 |
mRNA levels of dipeptidyl peptidase IV decrease during intestinal adaptation.
Topics: Adaptation, Physiological; Animals; Dipeptidyl Peptidase 4; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Intestines; Peptide Fragments; Peptides; Protein Precursors; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1999 |
Glucagon-like peptide-1-(7-36)amide is transformed to glucagon-like peptide-1-(9-36)amide by dipeptidyl peptidase IV in the capillaries supplying the L cells of the porcine intestine.
Topics: Animals; Capillaries; Chromatography, High Pressure Liquid; Dipeptidyl Peptidase 4; Endothelium, Vascular; Epithelium; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Histocytochemistry; Immunohistochemistry; Intestinal Mucosa; Microvilli; Peptide Fragments; Peptides; Swine | 1999 |
Twenty-four-hour insulin secretion rates, circulating concentrations of fuel substrates and gut incretin hormones in healthy offspring of Type II (non-insulin-dependent) diabetic parents: evidence of several aberrations.
Topics: Adult; Blood; Blood Glucose; C-Peptide; Circadian Rhythm; Diabetes Mellitus, Type 2; Eating; Energy Metabolism; Fatty Acids, Nonesterified; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Tolerance Test; Humans; Insulin; Insulin Secretion; Intestinal Mucosa; Male; Middle Aged; Peptide Fragments; Proinsulin; Reference Values | 1999 |
Inhibition of dipeptidyl peptidase IV with NVP-DPP728 increases plasma GLP-1 (7-36 amide) concentrations and improves oral glucose tolerance in obese Zucker rats.
Topics: Animals; Dipeptidyl Peptidase 4; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glucose Tolerance Test; Male; Nitriles; Obesity; Osmolar Concentration; Peptide Fragments; Pyrrolidines; Rats; Rats, Zucker; Reference Values | 1999 |
A functional role for central glucagon-like peptide-1 receptors in lithium chloride-induced anorexia.
Topics: Animals; Anorexia; Brain; Dose-Response Relationship, Drug; Eating; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Injections, Intraventricular; Lithium Chloride; Male; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptors, Glucagon | 1999 |
Neural contribution to the effect of glucagon-like peptide-1-(7-36) amide on arterial blood pressure in rats.
Topics: Animals; Blood Pressure; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Heart Rate; Humans; Injections, Intravenous; Injections, Intraventricular; Male; Neurotransmitter Agents; Peptide Fragments; Peptides; Rats; Rats, Sprague-Dawley; Vagotomy; Vagus Nerve | 1999 |
Glucose intolerance caused by a defect in the entero-insular axis: a study in gastric inhibitory polypeptide receptor knockout mice.
Topics: Administration, Oral; Animals; Diabetes Mellitus, Type 2; Dietary Fats; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glucose Intolerance; Glucose Tolerance Test; Homeostasis; Injections, Intraperitoneal; Insulin; Insulin Resistance; Insulin Secretion; Intestines; Islets of Langerhans; Mice; Mice, Knockout; Models, Biological; Peptide Fragments; Protein Precursors; Receptors, Gastrointestinal Hormone | 1999 |
Effects of substitution of N-terminal amino acid of glucagon-like peptide-1 (7-36) amide on food intake of the neonatal chick.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Animals, Newborn; Chickens; Eating; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Histidine; Injections, Intraventricular; Male; Molecular Sequence Data; Peptide Fragments; Protein Precursors; Structure-Activity Relationship; Tyrosine | 1999 |
Increased glucagon-like peptide-1 receptor expression in glia after mechanical lesion of the rat brain.
Topics: Animals; Brain Injuries; Gene Expression; Glial Fibrillary Acidic Protein; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; In Situ Hybridization; Male; Neuroglia; Peptide Fragments; Rats; Rats, Wistar; Receptors, Glucagon; RNA, Messenger; Wounds, Stab | 1999 |
The role of CNS glucagon-like peptide-1 (7-36) amide receptors in mediating the visceral illness effects of lithium chloride.
Topics: Angiotensins; Animals; Avoidance Learning; Cerebral Ventricles; Drinking Behavior; Energy Intake; Feeding Behavior; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Injections, Intraventricular; Kaolin; Lithium Chloride; Male; Peptide Fragments; Rats; Rats, Long-Evans; Receptors, Glucagon; Sodium, Dietary; Taste; Time Factors | 2000 |
An osmotic stimulus-mediating glucagon-like peptide-1 (7-36 amide) (GLP-1) secretion in acarbose-induced sucrose malabsorption?
Topics: Acarbose; Adult; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Intestinal Absorption; Male; Middle Aged; Osmolar Concentration; Peptide Fragments; Sucrose | 2000 |
N-terminally modified glucagon-like peptide-1(7-36) amide exhibits resistance to enzymatic degradation while maintaining its antihyperglycaemic activity in vivo.
Topics: Animals; Blood Glucose; Chromatography, High Pressure Liquid; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Homeostasis; Humans; Hypoglycemic Agents; Insulin; Male; Peptide Fragments; Peptides; Rats; Rats, Wistar; Sorbitol | 2000 |
Structure, measurement, and secretion of human glucagon-like peptide-2.
Topics: Chromatography, High Pressure Liquid; Glucagon; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Humans; Ileum; Mass Spectrometry; Pancreas; Peptide Fragments; Peptides; Proglucagon; Protein Precursors; Radioimmunoassay | 2000 |
Does the response of the intestinal epithelium to keratinocyte growth factor vary according to the method of administration?
Topics: Animals; Body Weight; Fibroblast Growth Factor 10; Fibroblast Growth Factor 7; Fibroblast Growth Factors; Gastrins; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Growth Substances; Intestinal Mucosa; Male; Metaphase; Organ Size; Peptide Fragments; Peptide YY; Protein Precursors; Rats; Rats, Wistar | 2000 |
The hepatic vagal reception of intraportal GLP-1 is via receptor different from the pancreatic GLP-1 receptor.
Topics: Animals; Electrophysiology; Exenatide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Injections, Intravenous; Liver; Male; Neurons, Afferent; Pancreas; Peptide Fragments; Peptides; Portal Vein; Rats; Rats, Wistar; Receptors, Glucagon; Vagus Nerve; Venoms | 2000 |
Oxyntomodulin inhibits pancreatic secretion through the nervous system in rats.
Topics: Animals; Deoxyglucose; Drug Interactions; Glicentin; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Kinetics; Male; Oxyntomodulin; Pancreas; Peptide Fragments; Peptide YY; Protein Precursors; Rats; Rats, Wistar; Sincalide; Vagus Nerve | 2000 |
Deficiency of the intestinal growth factor, glucagon-like peptide 2, in the colon of SCID mice with inflammatory bowel disease induced by transplantation of CD4+ T cells.
Topics: Animals; CD4-Positive T-Lymphocytes; Colon; Disease Models, Animal; Glucagon; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Growth Substances; Inflammatory Bowel Diseases; Mice; Mice, SCID; Peptide Fragments | 2000 |
Peripheral versus central effects of glucagon-like peptide-1 receptor agonists on satiety and body weight loss in Zucker obese rats.
Topics: Amines; Animals; Appetite; Body Weight; Brain; Diabetes Mellitus; Drinking; Eating; Exenatide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; In Situ Hybridization; Injections, Intraventricular; Injections, Subcutaneous; Male; Obesity; Peptide Fragments; Peptides; Rats; Rats, Wistar; Rats, Zucker; Receptors, Glucagon; RNA, Messenger; Venoms | 2000 |
Glucagon-like peptide-1 improves insulin and proinsulin binding on RINm5F cells and human monocytes.
Topics: Adult; Animals; Exenatide; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Humans; Insulin; Insulinoma; Male; Monocytes; Pancreatic Neoplasms; Peptide Fragments; Peptides; Proinsulin; Protein Precursors; Rats; Receptors, Glucagon; Tumor Cells, Cultured; Venoms | 2000 |
Characterisation of beta-cell dysfunction of impaired glucose tolerance: evidence for impairment of incretin-induced insulin secretion.
Topics: Adult; Arginine; Blood Glucose; C-Peptide; Fasting; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Clamp Technique; Glucose Intolerance; Glycated Hemoglobin; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Peptide Fragments; Reference Values | 2000 |
Effects of centrally or systemically injected glucagon-like peptide-1 (7-36) amide on release of neurohypophysial hormones and blood pressure in the rat.
Topics: Animals; Blood Pressure; Dose-Response Relationship, Drug; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Hypertension; Injections, Intravenous; Male; Neurotransmitter Agents; Oxytocin; Peptide Fragments; Radioimmunoassay; Rats; Rats, Wistar; Sex Factors; Time Factors; Vasopressins | 2000 |
Portal GLP-1 administration in rats augments the insulin response to glucose via neuronal mechanisms.
Topics: Animals; Atropine Derivatives; Blood Glucose; Chlorisondamine; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Injections, Intravenous; Insulin; Insulin Secretion; Jugular Veins; Kinetics; Male; Parasympatholytics; Peptide Fragments; Portal Vein; Rats; Rats, Sprague-Dawley; Time Factors | 2000 |
Effects of glucagon-like peptide-1 (GLP-1) on glucose homeostasis and food intake.
Topics: Animals; Dipeptidyl Peptidase 4; Eating; Feeding Behavior; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Homeostasis; Insulin; Intestinal Mucosa; Neurotransmitter Agents; Nitriles; Peptide Fragments; Protease Inhibitors; Pyrrolidines; Rats | 2000 |
Glucagonlike peptide-2 analogue enhances intestinal mucosal mass and absorptive function after ischemia-reperfusion injury.
Topics: Animals; Disease Models, Animal; DNA; Galactose; Glucagon-Like Peptides; Glycine; Infusions, Intravenous; Intestinal Absorption; Intestinal Mucosa; Male; Peptides; Probability; Rats; Rats, Sprague-Dawley; Reference Values; Reperfusion Injury | 2000 |
Ontogeny of the glucagon-like peptide-2 receptor axis in the developing rat intestine.
Topics: Animals; Animals, Newborn; Colon; Gene Expression; Glucagon; Glucagon-Like Peptide 2; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Intestinal Mucosa; Intestine, Small; Intestines; Organ Size; Peptides; Proglucagon; Protein Precursors; Rats; Rats, Wistar; Receptors, Glucagon; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stomach | 2000 |
Degradation and glycemic effects of His(7)-glucitol glucagon-like peptide-1(7-36)amide in obese diabetic ob/ob mice.
Topics: Animals; Blood Glucose; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Eating; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Mice; Mice, Obese; Oligopeptides; Peptide Fragments; Protease Inhibitors; Protein Precursors; Spectrometry, Mass, Electrospray Ionization; Time Factors | 2001 |
Lack of effect of incretin hormones on insulin release from pancreatic islets in the bile duct-ligated rats.
Topics: Animals; Bile Ducts; Bilirubin; Bucladesine; Cholestasis, Extrahepatic; Colforsin; Cyclic AMP; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glucose Tolerance Test; Heterotrimeric GTP-Binding Proteins; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Ligation; Male; Peptide Fragments; Rats; Rats, Wistar | 2001 |
A new hypoglycemic agent, JTT-608, evokes protein kinase A-mediated Ca(2+) signaling in rat islet beta-cells: strict regulation by glucose, link to insulin release, and cooperation with glucagon-like peptide-1(7-36)amide and pituitary adenylate cyclase-ac
Topics: Acetylcholine; Animals; Butyrates; Calcium Channel Blockers; Calcium Signaling; Cell Separation; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Cyclohexanes; Enzyme Activation; Enzyme Inhibitors; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Hypoglycemic Agents; Insulin; Islets of Langerhans; Neuropeptides; Peptide Fragments; Pituitary Adenylate Cyclase-Activating Polypeptide; Rats; Rats, Wistar | 2001 |
Differential effects of glucagon-like peptide-1 (7-36)amide versus cholecystokinin on arginine-induced islet hormone release in vivo and in vitro.
Topics: Animals; Arginine; Cholecystokinin; Drug Combinations; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Insulin; Insulin Secretion; Male; Mice; Pancreas; Peptide Fragments; Perfusion; Rats; Somatostatin | 2001 |
Glucagon-like peptide 1 stimulates lipolysis in clonal pancreatic beta-cells (HIT).
Topics: Calcium; Cell Line; Enzyme Inhibitors; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Hydrogen-Ion Concentration; Intracellular Membranes; Islets of Langerhans; Lactones; Lipase; Lipolysis; Orlistat; Peptide Fragments; Protein Precursors; Sterol Esterase | 2001 |
Autotransplantation modulates ileal enteroendocrine cell expression in the pig.
Topics: Anastomosis, Surgical; Animals; Enterochromaffin Cells; Female; Glicentin; Glucagon; Glucagon-Like Peptides; Ileum; Intestinal Mucosa; Intestine, Small; Jejunum; Neurotensin; Peptide Fragments; Protein Precursors; Somatostatin; Swine; Transplantation, Autologous | 2001 |
Synergistic interaction between VIP-related peptides and bombesin on ion transport in guinea pig distal colonic mucosa.
Topics: Animals; Bombesin; Colon; Dose-Response Relationship, Drug; Drug Synergism; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Guinea Pigs; In Vitro Techniques; Intestinal Mucosa; Ion Transport; Male; Neuropeptides; Peptide Fragments; Peptides; Pituitary Adenylate Cyclase-Activating Polypeptide; Vasoactive Intestinal Peptide | 2000 |
Distinctive effects of glicentin, GLP-1 and GLP-2 on adaptive response to massive distal small intestine resection in rats.
Topics: Adaptation, Physiological; alpha-Glucosidases; Animals; DNA; Glicentin; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Growth Substances; Intestine, Small; Male; Organ Size; Peptide Fragments; Peptides; Protein Precursors; Proteins; Rats; Rats, Wistar; Sucrase; Time Factors | 2000 |
Cytosolic calcium handling in islets of normal Wistar and diabetic Goto Kakizaki rats in the presence of glucose and truncated glucagon-like peptide 1 (7-36) amide.
Topics: Animals; Calcium; Cytosol; Diabetes Mellitus, Type 2; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Peptide Fragments; Rats; Rats, Wistar | 2000 |
Regulatory peptides: what do they regulate?
Topics: Carrier Proteins; Conotoxins; Cytokines; DNA-Binding Proteins; Endopeptidases; Glucagon-Like Peptides; Homeostasis; Humans; Inflammatory Bowel Diseases; Mathematics; Models, Biological; Neoplasms; Neuropeptides; Peptides; Transcription Factors | 2001 |
Action of glucagon and glucagon-like peptide-1-(7-36) amide on lipolysis in human subcutaneous adipose tissue and skeletal muscle in vivo.
Topics: Adipose Tissue; Adult; Blood Flow Velocity; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glycerol; Humans; Isoproterenol; Lipolysis; Male; Microdialysis; Muscle, Skeletal; Peptide Fragments | 2001 |
Effect of glucagon-like peptide-1(7-36)-amide on initial splanchnic glucose uptake and insulin action in humans with type 1 diabetes.
Topics: Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Duodenum; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Human Growth Hormone; Hydrocortisone; Hypoglycemic Agents; Insulin; Intubation; Osmolar Concentration; Peptide Fragments; Viscera | 2001 |
Glucagon-like peptide-1(7-36) amide stimulates surfactant secretion in human type II pneumocytes.
Topics: Adult; Cells, Cultured; Dose-Response Relationship, Drug; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Lung; Male; Middle Aged; Peptide Fragments; Phosphatidylcholines; Pulmonary Surfactants; Reference Values; Sensitivity and Specificity | 2001 |
GLP-2alpha accelerates recovery of mucosal absorptive function after intestinal ischemia/reperfusion.
Topics: Analysis of Variance; Animals; Disease Models, Animal; Galactose; Glucagon-Like Peptides; Glycine; Infusions, Intravenous; Intestinal Absorption; Intestinal Mucosa; Ischemia; Male; Peptides; Probability; Rats; Rats, Sprague-Dawley; Reference Values; Reperfusion; Treatment Outcome | 2001 |
Glucagon-like peptide-1 (7-37) augments insulin release in elderly patients with diabetes.
Topics: Aged; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Clamp Technique; Humans; Infusions, Intravenous; Insulin; Insulin Secretion; Peptide Fragments; Peptides | 2001 |
Involvement of calmodulin in glucagon-like peptide 1(7-36) amide-induced inhibition of the ATP-sensitive K+ channel in mouse pancreatic beta-cells.
Topics: Adenosine Triphosphate; Animals; Calcium; Calmodulin; Electrophysiology; Enzyme Inhibitors; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Hypoglycemic Agents; Imidazoles; Islets of Langerhans; Male; Membrane Potentials; Mice; Mice, Inbred ICR; Peptide Fragments; Potassium Channels; Sulfonamides; Tolbutamide | 2001 |
Glucose competence of the hepatoportal vein sensor requires the presence of an activated glucagon-like peptide-1 receptor.
Topics: Animals; Blood Glucose; Catheters, Indwelling; Enzyme-Linked Immunosorbent Assay; Fasting; Femoral Vein; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Hepatic Veins; Homeostasis; Infusions, Intravenous; Metabolic Clearance Rate; Mice; Mice, Inbred C57BL; Peptide Fragments; Portal System; Portal Vein; Protein Precursors; Tritium; Venoms | 2001 |
The role of postprandial releases of insulin and incretin hormones in meal-induced satiety--effect of obesity and weight reduction.
Topics: Absorptiometry, Photon; Adult; Appetite; Area Under Curve; Energy Intake; Gastric Emptying; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Insulin Resistance; Insulin Secretion; Male; Middle Aged; Obesity; Peptide Fragments; Postprandial Period; Satiation; Weight Loss | 2001 |
The effect of glucagon-like peptide 2 on intestinal permeability and bacterial translocation in acute necrotizing pancreatitis.
Topics: Analysis of Variance; Animals; Bacterial Translocation; Glucagon; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Ileum; Intestinal Mucosa; Jejunum; Male; Pancreatitis, Acute Necrotizing; Peptides; Permeability; Rats; Rats, Sprague-Dawley; Weight Loss | 2001 |
Reduction of incretin-like salivatin in saliva from patients with type 2 diabetes and in parotid glands of streptozotocin-diabetic BALB/c mice.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Eating; Enzyme-Linked Immunosorbent Assay; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Hypoglycemic Agents; Male; Mice; Mice, Inbred BALB C; Microscopy, Immunoelectron; Parotid Gland; Peptide Fragments; Peptides; Postprandial Period; Proline-Rich Protein Domains; Saliva; Salivary Proline-Rich Proteins | 2001 |
Urinary excretion of glucagon-like peptide 1 (GLP-1) 7-36 amide in human type 2 (non-insulin-dependent) diabetes mellitus.
Topics: Aged; Albuminuria; Body Mass Index; C-Peptide; Creatinine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glycated Hemoglobin; Humans; Male; Metabolic Clearance Rate; Middle Aged; Peptide Fragments | 2001 |
Glicentin, an active enteroglucagon, has a significant trophic role on the small intestine but not on the colon in the rat.
Topics: Animals; Cell Division; Colon; Duodenum; Glicentin; Glucagon; Glucagon-Like Peptides; Ileum; Intestine, Small; Jejunum; Male; Metaphase; Parenteral Nutrition, Total; Peptide Fragments; Protein Precursors; Rats; Rats, Wistar; Recombinant Proteins | 2001 |
Effect of glucagon, glicentin, glucagon-like peptide-1 and -2 on interdigestive gastroduodenal motility in dogs with a vagally denervated gastric pouch.
Topics: Animals; Dogs; Female; Gastrointestinal Motility; Glicentin; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Male; Peptide Fragments; Peptides; Protein Precursors; Stomach; Vagotomy | 2001 |
Critical role of cAMP-GEFII--Rim2 complex in incretin-potentiated insulin secretion.
Topics: Animals; Base Sequence; Carrier Proteins; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DNA Primers; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; GTP-Binding Proteins; Guanine Nucleotide Exchange Factors; Imines; Insulin; Insulin Secretion; Islets of Langerhans; Mice; Nerve Tissue Proteins; Nuclear Proteins; Peptide Fragments; Protein Precursors | 2001 |
The intestinal stem cell niche: there grows the neighborhood.
Topics: Animals; Cell Division; Ethylnitrosourea; Glucagon-Like Peptides; Intestinal Mucosa; Mice; Neurons; Peptides; Stem Cells | 2001 |
GLP-2 has differential effects on small intestine growth and function in fetal and neonatal pigs.
Topics: Animals; Animals, Newborn; Embryonic and Fetal Development; Female; Fetus; Gene Expression Regulation, Developmental; Glucagon; Glucagon-Like Peptide 2; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Humans; Intestine, Small; Peptides; Pregnancy; Rats; Receptors, Glucagon; Swine; Transcription, Genetic | 2001 |
Vasorelaxant effect of glucagon-like peptide-(7-36)amide and amylin on the pulmonary circulation of the rat.
Topics: Acetylcholine; Amyloid; Animals; Anti-Ulcer Agents; Calcitonin Gene-Related Peptide; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; In Vitro Techniques; Islet Amyloid Polypeptide; Male; Neurotransmitter Agents; NG-Nitroarginine Methyl Ester; Norepinephrine; Peptide Fragments; Perfusion; Pulmonary Artery; Pulmonary Circulation; Pulmonary Ventilation; Rats; Rats, Sprague-Dawley; Trachea; Vasoactive Intestinal Peptide; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2001 |
Increased expression of ileal apical sodium-dependent bile acid transporter in postpartum rats.
Topics: Alkaline Phosphatase; Animals; Bile Acids and Salts; Carrier Proteins; Dietary Fats; Enterohepatic Circulation; Female; Gene Expression; Glucagon-Like Peptides; Ileum; Intestinal Absorption; Lactation; Liver; Organic Anion Transporters, Sodium-Dependent; Ovariectomy; Peptides; Postpartum Period; Pregnancy; Prolactin; Rats; RNA, Messenger; Symporters; Taurocholic Acid | 2002 |
Large lymph node metastasis gives hint to a glicentin positive small endocrine rectal carcinoma.
Topics: Aged; Biopsy, Needle; Colectomy; Female; Follow-Up Studies; Glicentin; Glucagon; Glucagon-Like Peptides; Humans; Immunohistochemistry; Lymph Node Excision; Lymph Nodes; Lymphatic Metastasis; Neuroendocrine Tumors; Peptide Fragments; Protein Precursors; Rectal Neoplasms; Tomography, X-Ray Computed; Treatment Outcome | 2001 |
Renal effects of glucagon-like peptide in rats.
Topics: Animals; Dose-Response Relationship, Drug; Glomerular Filtration Rate; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Kidney; Male; Neurotransmitter Agents; Peptide Fragments; Rats; Rats, Sprague-Dawley | 2002 |
tGLP-1 and release of vasopressin and oxytocin from the isolated rat hypothalamo-neurohypophysial system: effects of a tGLP-1 receptor agonist and antagonist.
Topics: Animals; Cyclic AMP; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Hypothalamo-Hypophyseal System; Hypothalamus, Middle; In Vitro Techniques; Male; Oxytocin; Peptide Fragments; Peptides; Rats; Rats, Wistar; Vasopressins | 2001 |
Effects of glucagon-like peptide-1(7-36) amide on neurohypophysial and cardiovascular functions under hypo- or normotensive hypovolaemia in the rat.
Topics: Analysis of Variance; Animals; Arginine Vasopressin; Blood Pressure; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Hypovolemia; Male; Oxytocin; Peptide Fragments; Pituitary Gland, Posterior; Rats; Rats, Wistar | 2002 |
Anxiogenic-like action of centrally administered glucagon-like peptide-1 in a punished drinking test.
Topics: Amygdala; Animals; Anxiety; Cerebral Ventricles; Conflict, Psychological; Drinking Behavior; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Infusions, Parenteral; Male; Maze Learning; Motor Activity; Peptide Fragments; Protein Precursors; Punishment; Rats; Rats, Sprague-Dawley | 2002 |
Evaluation of glycated glucagon-like peptide-1(7-36)amide in intestinal tissue of normal and diabetic animal models.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Disease Models, Animal; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glycosylation; Hydrocortisone; Intestine, Small; Mice; Mice, Obese; Organ Size; Peptide Fragments; Rats | 2002 |
GLP-1-(9-36) amide reduces blood glucose in anesthetized pigs by a mechanism that does not involve insulin secretion.
Topics: Anesthesia; Animals; Blood Glucose; Chloralose; Dipeptidyl Peptidase 4; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Infusions, Intravenous; Insulin; Insulin Secretion; Kinetics; Metabolic Clearance Rate; Peptide Fragments; Peptides; Protease Inhibitors; Protein Precursors; Pyrroles; Swine; Valine | 2002 |
Abnormal release of incretins and cortisol after oral glucose in subjects with insulin-resistant myotonic dystrophy.
Topics: Adult; Body Composition; DNA; Dose-Response Relationship, Drug; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Humans; Hydrocortisone; Insulin Resistance; Male; Middle Aged; Myotonic Dystrophy; Peptide Fragments; Regression Analysis; Repetitive Sequences, Nucleic Acid | 2002 |
Immunocytochemical and ultrastructural characterization of endocrine cells in the larval stomach of the frog Rana temporaria tadpoles: a comparison with adult specimens.
Topics: Animals; Bombesin; Digestive System; Glicentin; Glucagon; Glucagon-Like Peptides; Immunohistochemistry; Microscopy, Electron; Peptide Fragments; Protein Precursors; Rana temporaria; Serotonin; Silver Staining; Sincalide; Somatostatin; Stomach | 2001 |
Short-term administration of glucagon-like peptide-2. Effects on bone mineral density and markers of bone turnover in short-bowel patients with no colon.
Topics: Absorptiometry, Photon; Adult; Alkaline Phosphatase; Amino Acids; Bone Density; Bone Diseases, Metabolic; Bone Remodeling; Calcium; Female; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Hormones; Humans; Intestinal Absorption; Male; Middle Aged; Osteocalcin; Osteoporosis; Parathyroid Hormone; Peptides; Pilot Projects; Short Bowel Syndrome; Vitamin D | 2002 |
Hypocretin is an early member of the incretin gene family.
Topics: Animals; Anura; Carrier Proteins; Evolution, Molecular; Exons; Gene Expression Regulation; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Hypothalamus; Intracellular Signaling Peptides and Proteins; Neuropeptides; Orexins; Peptide Fragments; Phylogeny; Protein Structure, Secondary; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid; Sleep; Tetraodontiformes; Urochordata | 2002 |
Identification and functional characterization of melatonin Mel 1a receptors in pancreatic beta cells: potential role in incretin-mediated cell function by sensitization of cAMP signaling.
Topics: Animals; Cell Line; Circadian Rhythm; Cyclic AMP; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Islets of Langerhans; Melatonin; Peptide Fragments; Protein Precursors; Rats; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Second Messenger Systems | 2002 |
GLP-1 receptor signaling contributes to anorexigenic effect of centrally administered oxytocin in rats.
Topics: Animals; Anorexia; Eating; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Injections, Intraventricular; Male; Neurons; Neurotransmitter Agents; Oxytocin; Peptide Fragments; Protein Precursors; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Glucagon; Receptors, Oxytocin; Signal Transduction | 2002 |
Somatostatin-28 regulates GLP-1 secretion via somatostatin receptor subtype 5 in rat intestinal cultures.
Topics: Animals; Cells, Cultured; Fetus; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Intestinal Mucosa; Intestines; Peptide Fragments; Protein Precursors; Rats; Receptors, Somatostatin; Somatostatin; Somatostatin-28 | 2002 |
Glycemic, hormone, and appetite responses to monosaccharide ingestion in patients with type 2 diabetes.
Topics: Adult; Aged; Appetite; Blood Glucose; Diabetes Mellitus, Type 2; Female; Fructose; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Humans; Insulin; Male; Middle Aged; Peptide Fragments | 2002 |
tGLP-1 action on the isolated hypothalamo-neurohypophysial system under glutamate receptor blockade.
Topics: Animals; Arginine Vasopressin; Excitatory Amino Acid Antagonists; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Hypothalamo-Hypophyseal System; In Vitro Techniques; Male; Oxytocin; Peptide Fragments; Peptides; Pituitary-Adrenal System; Rats; Rats, Wistar; Receptors, Glutamate | 2002 |
Lack of effect of exendin-4 and glucagon-like peptide-1-(7,36)-amide on insulin action in non-diabetic humans.
Topics: Adult; Animals; Biotransformation; Blood Glucose; Body Mass Index; C-Peptide; Dipeptidyl Peptidase 4; Exenatide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Human Growth Hormone; Humans; Hydrocortisone; Infusions, Intravenous; Insulin; Kinetics; Lizards; Peptide Fragments; Peptides; Reference Values; Venoms | 2002 |
Elevated glucagon-like peptide-1-(7-36)-amide, but not glucose, associated with hyperinsulinemic compensation for fat feeding.
Topics: Animals; Blood Glucose; Blotting, Northern; Dietary Fats; Dogs; Fasting; Fatty Acids, Nonesterified; Gene Expression; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Glucose; Glucose Tolerance Test; Hyperinsulinism; Insulin; Insulin Resistance; Islets of Langerhans; Kinetics; Magnetic Resonance Imaging; Male; Obesity; Peptide Fragments; Receptors, Glucagon; Reverse Transcriptase Polymerase Chain Reaction | 2002 |
The diverse roles of specific GLP-1 receptors in the control of food intake and the response to visceral illness.
Topics: Amygdala; Animals; Anorexia; Appetite Regulation; Behavior, Animal; Catheterization; Conditioning, Psychological; Dose-Response Relationship, Drug; Eating; Fourth Ventricle; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Injections, Intraperitoneal; Injections, Intraventricular; Lateral Ventricles; Lithium Chloride; Male; Paraventricular Hypothalamic Nucleus; Peptide Fragments; Rats; Rats, Long-Evans; Receptors, Glucagon; Signal Transduction; Taste; Visceral Afferents | 2002 |
cAMP-activated protein kinase-independent potentiation of insulin secretion by cAMP is impaired in SUR1 null islets.
Topics: Animals; ATP-Binding Cassette Transporters; Carbazoles; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Indoles; Insulin; Insulin Secretion; Islets of Langerhans; Isoquinolines; Mice; Mice, Knockout; Peptide Fragments; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Kinase C; Pyrroles; Receptors, Drug; Reference Values; Sulfonamides; Sulfonylurea Receptors | 2002 |
The vagus is inhibitory of the late postprandial insulin secretion in conscious pigs.
Topics: Analysis of Variance; Animals; Area Under Curve; Blood Glucose; Consciousness; Female; Food; Gastric Emptying; Gastric Inhibitory Polypeptide; Gastric Mucosa; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Insulin; Insulin Secretion; Peptide Fragments; Postprandial Period; Protein Precursors; Radioimmunoassay; Stomach; Swine; Time Factors; Vagotomy; Vagus Nerve | 2002 |
Role of luminal nutrients and endogenous GLP-2 in intestinal adaptation to mid-small bowel resection.
Topics: Adaptation, Physiological; Animals; Apoptosis; Body Weight; Cell Division; Eating; Enterocytes; Glucagon; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Ileum; Jejunum; Male; Parenteral Nutrition; Peptides; Proglucagon; Protein Precursors; Rats; Rats, Sprague-Dawley; Sucrase | 2003 |
Comparisons of leptin, incretins and body composition in obese and lean patients with hypopituitarism and healthy individuals.
Topics: Adult; Anthropometry; Body Composition; Case-Control Studies; Cross-Sectional Studies; Fasting; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Human Growth Hormone; Humans; Hypopituitarism; Leptin; Lipids; Male; Middle Aged; Obesity; Peptide Fragments; Peptides; Thinness | 2003 |
Dipeptidyl peptidase IV inhibitor treatment stimulates beta-cell survival and islet neogenesis in streptozotocin-induced diabetic rats.
Topics: Animals; Blood Glucose; Cell Count; Cell Differentiation; Cell Division; Cell Survival; Diabetes Mellitus, Experimental; Dipeptidyl Peptidase 4; Eating; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Tolerance Test; Immunohistochemistry; Insulin; Insulin Secretion; Islets of Langerhans; Lipids; Liver; Male; Peptide Fragments; Phosphoenolpyruvate Carboxykinase (GTP); Protease Inhibitors; Protein Precursors; Rats; Rats, Wistar; Weight Gain | 2003 |
Mechanisms involved in glucagon-like peptide-1 (7-36) amide action on the rat hypothalamo-neurohypophysial system.
Topics: Analysis of Variance; Angiotensin II; Animals; Calcium; Colforsin; Cyclic AMP; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Hypothalamo-Hypophyseal System; Male; Neurotransmitter Agents; Organ Culture Techniques; Oxytocin; Peptide Fragments; Rats; Rats, Wistar; Second Messenger Systems; Vasopressins; Water-Electrolyte Balance | 2003 |
Effects of the novel (Pro3)GIP antagonist and exendin(9-39)amide on GIP- and GLP-1-induced cyclic AMP generation, insulin secretion and postprandial insulin release in obese diabetic (ob/ob) mice: evidence that GIP is the major physiological incretin.
Topics: Animals; Cells, Cultured; Cricetinae; Cricetulus; Cyclic AMP; Diabetes Mellitus; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Hyperinsulinism; Insulin; Insulin Secretion; Mice; Obesity; Peptide Fragments; Postprandial Period; Protein Precursors; Spectrometry, Mass, Electrospray Ionization | 2003 |
The intriguing diversity of the glucagon gene products.
Topics: Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Multigene Family; Peptide Fragments; Peptides; Protein Precursors | 2002 |
Expression, purification, and PC1-mediated processing of human proglucagon, glicentin, and major proglucagon fragment.
Topics: Electrophoresis, Polyacrylamide Gel; Furin; Glicentin; Glucagon; Glucagon-Like Peptides; Humans; Peptide Fragments; Proglucagon; Protein Precursors; Protein Processing, Post-Translational; Spectrometry, Mass, Electrospray Ionization | 2003 |
Differential activation mechanisms of Erk-1/2 and p70(S6K) by glucose in pancreatic beta-cells.
Topics: Animals; Calcium; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glyburide; Humans; Islets of Langerhans; Isoquinolines; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Peptide Fragments; Phosphorylation; Proto-Oncogene Proteins c-raf; Rats; Rats, Sprague-Dawley; Ribosomal Protein S6 Kinases, 70-kDa; Sulfonamides; Verapamil | 2003 |
Effect of glicentin on gut mucosal growth in rats with jejunal and ileal Thiry-Vella fistulas.
Topics: Anastomosis, Surgical; Animals; Glicentin; Glucagon; Glucagon-Like Peptides; Ileostomy; Ileum; Injections, Subcutaneous; Intestinal Mucosa; Jejunostomy; Jejunum; Male; Organ Size; Organ Specificity; Peptide Fragments; Protein Precursors; Rats; Rats, Wistar | 2003 |
Effects of GLP-1-(7-36)NH2, GLP-1-(7-37), and GLP-1- (9-36)NH2 on intravenous glucose tolerance and glucose-induced insulin secretion in healthy humans.
Topics: Adult; Blood Glucose; Fasting; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Tolerance Test; Humans; Insulin; Insulin Secretion; Kinetics; Male; Middle Aged; Peptide Fragments; Peptides; Protein Precursors | 2003 |
Glucagon-like peptide 1 (1-37) converts intestinal epithelial cells into insulin-producing cells.
Topics: Animals; Base Sequence; Cells, Cultured; DNA Primers; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Insulin; Intestinal Mucosa; Mice; Mice, Inbred C57BL; Peptides; Pregnancy; Reverse Transcriptase Polymerase Chain Reaction | 2003 |
Peptides that regulate food intake: glucagon-like peptide 1-(7-36) amide acts at lateral and medial hypothalamic sites to suppress feeding in rats.
Topics: Animals; Dose-Response Relationship, Drug; Feeding Behavior; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Hypothalamic Area, Lateral; Hypothalamus, Middle; Male; Peptide Fragments; Rats; Rats, Wistar; Time Factors | 2003 |
Incretin secretion in relation to meal size and body weight in healthy subjects and people with type 1 and type 2 diabetes mellitus.
Topics: Adult; Aged; Blood Glucose; Body Weight; C-Peptide; Case-Control Studies; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Feeding Behavior; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Male; Middle Aged; Obesity; Peptide Fragments; Protein Precursors; Random Allocation | 2003 |
Glucagon-like peptide-1 (7-36) amide prevents the accumulation of pyruvate and lactate in the ischemic and non-ischemic porcine myocardium.
Topics: Animals; Area Under Curve; Blood Glucose; Cardiovascular System; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Ischemia; Lactic Acid; Microdialysis; Myocardial Infarction; Myocardium; Peptide Fragments; Protein Precursors; Pyruvic Acid; Reperfusion Injury; Swine; Time Factors | 2003 |
Glucose-dependent insulinotropic peptide stimulates proliferation and TGF-beta release from MG-63 cells.
Topics: Alkaline Phosphatase; Blotting, Northern; Cell Differentiation; Cell Division; Cell Line, Tumor; Collagen; Dose-Response Relationship, Drug; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Humans; Insulin; Osteoblasts; Peptide Fragments; Peptides; RNA; Thymidine; Transforming Growth Factor beta | 2003 |
CNS glucagon-like peptide-1 receptors mediate endocrine and anxiety responses to interoceptive and psychogenic stressors.
Topics: Adrenocorticotropic Hormone; Amygdala; Animals; Anxiety; Brain; Catheterization; Central Nervous System; Corticosterone; Corticotropin-Releasing Hormone; Dose-Response Relationship, Drug; Drug Administration Routes; Endocrine System; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Hypothalamo-Hypophyseal System; Male; Neuroprotective Agents; Paraventricular Hypothalamic Nucleus; Peptide Fragments; Pituitary-Adrenal System; Rats; Rats, Long-Evans; Receptors, Corticotropin-Releasing Hormone; Receptors, Glucagon; Stress, Psychological | 2003 |
Postnatal and postprandial changes in plasma concentrations of glicentin in term and preterm infants.
Topics: Breast Feeding; Fasting; Female; Glicentin; Glucagon; Glucagon-Like Peptides; Humans; Infant; Infant Food; Infant, Newborn; Infant, Premature; Male; Peptide Fragments; Postprandial Period; Protein Precursors | 2003 |
Novel dipeptidyl peptidase IV resistant analogues of glucagon-like peptide-1(7-36)amide have preserved biological activities in vitro conferring improved glucose-lowering action in vivo.
Topics: Amino Acid Substitution; Animals; Cells, Cultured; Cricetinae; Cyclic AMP; Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Enzymes; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Insulin; Insulin Secretion; Mice; Mice, Obese; Peptide Fragments; Receptors, Glucagon; Spectrometry, Mass, Electrospray Ionization | 2003 |
Characterisation of human dipeptidyl peptidase IV expressed in Pichia pastoris. A structural and mechanistic comparison between the recombinant human and the purified porcine enzyme.
Topics: Adenosine Deaminase; Amino Acid Sequence; Animals; Base Sequence; Catalytic Domain; Cloning, Molecular; Dipeptides; Dipeptidyl Peptidase 4; Enzyme Inhibitors; Fluorescent Dyes; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glycoproteins; Humans; Isoelectric Point; Kidney; Kinetics; Molecular Sequence Data; Molecular Weight; Peptide Fragments; Peptides; Pichia; Protein Binding; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Swine | 2003 |
N-acetyl-GLP-1: a DPP IV-resistant analogue of glucagon-like peptide-1 (GLP-1) with improved effects on pancreatic beta-cell-associated gene expression.
Topics: Animals; Base Sequence; Cell Differentiation; Cell Line, Tumor; Gene Expression; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Islets of Langerhans; Molecular Sequence Data; Pancreatic Ducts; Peptide Fragments; Rats | 2004 |
Lys9 for Glu9 substitution in glucagon-like peptide-1(7-36)amide confers dipeptidylpeptidase IV resistance with cellular and metabolic actions similar to those of established antagonists glucagon-like peptide-1(9-36)amide and exendin (9-39).
Topics: Adenylyl Cyclases; Amino Acid Substitution; Animals; Blood Glucose; Cells, Cultured; Cricetinae; Cyclic AMP; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Fibroblasts; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Glutamic Acid; Humans; Hypoglycemic Agents; Insulin; Islets of Langerhans; Lung; Lysine; Mice; Mice, Obese; Peptide Fragments; Peptides; Receptors, Glucagon; Spectrometry, Mass, Electrospray Ionization | 2004 |
Peripheral oxyntomodulin reduces food intake and body weight gain in rats.
Topics: Animals; Appetite Depressants; Arcuate Nucleus of Hypothalamus; Darkness; Dose-Response Relationship, Drug; Drug Administration Schedule; Eating; Fasting; Gastric Emptying; Ghrelin; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Humans; Immunohistochemistry; Injections; Injections, Intraperitoneal; Male; Oxyntomodulin; Peptide Fragments; Peptide Hormones; Photoperiod; Protein Precursors; Rats; Rats, Wistar; Receptors, Glucagon; Weight Gain | 2004 |
Cultured gastrointestinal smooth muscle cells: cell response to contractile agonists depends on their phenotypic state.
Topics: Animals; Carbachol; Cell Differentiation; Cell Proliferation; Cells, Cultured; Extracellular Signal-Regulated MAP Kinases; Gastrins; Glicentin; Glucagon; Glucagon-Like Peptides; Inositol Phosphates; Muscle Contraction; Muscle, Smooth; Myosin Heavy Chains; Peptide Fragments; Protein Precursors; Pyloric Antrum; Rabbits; Receptors, Muscarinic; Signal Transduction | 2004 |
N-terminal His(7)-modification of glucagon-like peptide-1(7-36) amide generates dipeptidyl peptidase IV-stable analogues with potent antihyperglycaemic activity.
Topics: Animals; Cell Line, Transformed; Cricetinae; Cyclic AMP; Diabetes Mellitus; Dipeptidyl Peptidase 4; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Hypoglycemic Agents; Insulin; Mesocricetus; Mice; Mice, Obese; Peptide Fragments; Protein Precursors; Pyrrolidonecarboxylic Acid | 2004 |
Glucagonlike peptide-2 analogue: a possible new approach in the management of inflammatory bowel disease.
Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents; Defecation; Diarrhea; Disease Models, Animal; Female; Glucagon-Like Peptides; HLA-B27 Antigen; Ileum; Inflammatory Bowel Diseases; Injections, Intravenous; Intestinal Mucosa; Peptides; Rats; Rats, Inbred F344; Rats, Mutant Strains | 2004 |
Simultaneous determination of incretin hormones and their truncated forms from human plasma by immunoprecipitation and liquid chromatography-mass spectrometry.
Topics: Chromatography, High Pressure Liquid; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Mass Spectrometry; Peptide Fragments; Precipitin Tests; Sensitivity and Specificity | 2004 |
Effect of GLP-1 (glucagon-like peptide 1:7-36 amide) on porcine pancreatic endocrine cell proliferation and insulin secretion.
Topics: Animals; Cell Proliferation; Cells, Cultured; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Peptide Fragments; Potassium; RNA, Messenger; Swine | 2004 |
RyR2 and calpain-10 delineate a novel apoptosis pathway in pancreatic islets.
Topics: Animals; Apoptosis; Calcium; Calpain; Caspase 3; Caspases; Cell Survival; Dantrolene; Enzyme Activation; Gene Expression Regulation; Glucagon-Like Peptides; Glucose; Humans; Islets of Langerhans; Mice; Mice, Knockout; Mice, Transgenic; Microscopy, Confocal; Microscopy, Fluorescence; Models, Biological; Palmitic Acids; Peptides; Protein Isoforms; RNA, Messenger; Ryanodine; Ryanodine Receptor Calcium Release Channel; Time Factors | 2004 |
Effect of GIP, GLP-1, insulin and gastrin on ghrelin release in the isolated rat stomach.
Topics: Animals; Dose-Response Relationship, Drug; Gastric Inhibitory Polypeptide; Gastric Mucosa; Gastrins; Ghrelin; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Insulin; Male; Peptide Fragments; Peptide Hormones; Protein Precursors; Radioimmunoassay; Rats; Rats, Wistar; Somatostatin; Time Factors | 2004 |
Glucagon-like peptide-1 prevents beta cell glucolipotoxicity.
Topics: Apoptosis; Cell Line; Cells, Cultured; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Humans; Islets of Langerhans; NF-kappa B; Nitriles; Palmitic Acid; Peptide Fragments; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Sulfones | 2004 |
A gut response. The next generation of type 2 drugs.
Topics: Diabetes Mellitus, Type 2; Exenatide; Ghrelin; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Hypoglycemic Agents; Peptide Fragments; Peptide Hormones; Peptide YY; Peptides; Protein Precursors; United States; Venoms | 2004 |
Onset of small intestinal atrophy is associated with reduced intestinal blood flow in TPN-fed neonatal piglets.
Topics: Animals; Animals, Newborn; Apoptosis; Atrophy; Cell Division; DNA; Enteral Nutrition; Female; Food Deprivation; Glucagon-Like Peptides; Intestinal Mucosa; Intestine, Small; Nitric Oxide Synthase; Organ Size; Parenteral Nutrition, Total; Peptides; Portal System; Protein Biosynthesis; Regional Blood Flow; Survival Rate; Swine; Time Factors | 2004 |
Prior in vitro exposure to GLP-1 with or without GIP can influence the subsequent beta cell responsiveness.
Topics: Animals; Drug Combinations; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Insulin; Islets of Langerhans; Male; Peptide Fragments; Protein Precursors; Rats; Rats, Wistar; Receptors, G-Protein-Coupled | 2004 |
Glucagon-like peptide 2 improves intestinal wound healing through induction of epithelial cell migration in vitro-evidence for a TGF--beta-mediated effect.
Topics: Animals; Antibodies, Monoclonal; Apoptosis; Cell Line; Cell Line, Tumor; Cell Movement; Cell Proliferation; Epithelial Cells; Flow Cytometry; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Humans; Intestines; Peptide Fragments; Peptides; Protein Precursors; Rats; Transforming Growth Factor beta; Transforming Growth Factor beta1; Wound Healing | 2004 |
Oxyntomodulin and glucagon-like peptide-1 differentially regulate murine food intake and energy expenditure.
Topics: Amino Acid Sequence; Animals; Binding, Competitive; Brain; Cells, Cultured; Cricetinae; Dose-Response Relationship, Drug; Eating; Energy Metabolism; Exenatide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Injections, Intraperitoneal; Injections, Intraventricular; Iodine Radioisotopes; Mice; Mice, Inbred C57BL; Mice, Knockout; Molecular Sequence Data; Oxyntomodulin; Peptide Fragments; Peptides; Proglucagon; Protein Precursors; Proto-Oncogene Proteins c-fos; Rats; Receptors, G-Protein-Coupled; Receptors, Glucagon; Venoms | 2004 |
Oxyntomodulin and glicentin are potent inhibitors of the fed motility pattern in small intestine.
Topics: Animals; Eating; Gastrointestinal Motility; Glicentin; Glucagon; Glucagon-Like Peptides; Intestine, Small; Male; Oxyntomodulin; Peptide Fragments; Protein Precursors; Rats; Rats, Wistar | 2004 |
Identification of CJC-1131-albumin bioconjugate as a stable and bioactive GLP-1(7-36) analog.
Topics: Amino Acid Sequence; Animals; CHO Cells; Cricetinae; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Maleimides; Molecular Sequence Data; Peptide Fragments; Peptides; Protein Binding; Serum Albumin | 2004 |
Inulin-type fructans modulate gastrointestinal peptides involved in appetite regulation (glucagon-like peptide-1 and ghrelin) in rats.
Topics: Animals; Appetite Regulation; Cecum; Colon; Diet; Eating; Energy Intake; Ghrelin; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Inulin; Male; Organ Size; Peptide Fragments; Peptide Hormones; Proglucagon; Protein Precursors; Rats; Rats, Wistar; RNA, Messenger; Weight Gain | 2004 |
S 23521 decreases food intake and body weight gain in diet-induced obese rats.
Topics: Adipose Tissue; Animals; Anti-Obesity Agents; Dose-Response Relationship, Drug; Eating; Energy Metabolism; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Obesity; Peptide Fragments; Random Allocation; Rats; Rats, Wistar; Time Factors; Weight Gain | 2004 |
Treatment of suckling rats with GLP-2 plus dexamethasone increases the ileal uptake of fatty acids in later life.
Topics: Absorption; Animals; Animals, Newborn; Dexamethasone; Dietary Fats; Fatty Acids; Female; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Glucocorticoids; Ileum; Pancreatic Hormones; Peptides; Protein Precursors; Random Allocation; Rats; Rats, Sprague-Dawley; Weaning | 2005 |
Synthesis, bioactivity and specificity of glucagon-like peptide-1 (7-37)/polymer conjugate to isolated rat islets.
Topics: Animals; Cell Culture Techniques; Cells, Cultured; Coated Materials, Biocompatible; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Insulin; Insulin Secretion; Islets of Langerhans; Islets of Langerhans Transplantation; Male; Materials Testing; Pancreas, Artificial; Peptide Fragments; Peptides; Polymers; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Tissue Engineering | 2005 |
GLP-1 reduces intestinal lymph flow, triglyceride absorption, and apolipoprotein production in rats.
Topics: Animals; Apolipoproteins A; Apolipoproteins B; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Lymph; Male; Peptide Fragments; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Time Factors; Triglycerides | 2005 |
Effect of glucagon-like peptide-1(7-36) and exendin-4 on the vascular reactivity in streptozotocin/nicotinamide-induced diabetic rats.
Topics: Animals; Aorta, Thoracic; Blood Glucose; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Exenatide; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Oxidative Stress; Peptide Fragments; Peptides; Rats; Rats, Wistar; Streptozocin; Vasodilator Agents; Venoms | 2005 |
Proceedings from the GLP1 Meeting on the Occasion of the 80th Birthday of Prof. Dr. med. Dr. hc (em.) Werner Creutzfeldt.
Topics: Animals; Diabetes Mellitus, Type 2; Gastroenterology; Gastrointestinal Diseases; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; History, 20th Century; History, 21st Century; Humans; Liver Diseases; Pancreatic Diseases; Peptide Fragments; Peptides; Protein Precursors | 2005 |
The [pre-] history of the incretin concept.
Topics: Animals; Diabetes Mellitus; Gastric Inhibitory Polypeptide; Gastrin-Releasing Peptide; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; History, 20th Century; History, 21st Century; Humans; Hypoglycemic Agents; Insulin; Insulin Secretion; Peptide Fragments; Peptides; Protein Precursors; Secretin | 2005 |
Contraction induced by glicentin on smooth muscle cells from the human colon is abolished by exendin (9-39).
Topics: Adult; Aged; Aged, 80 and over; Amino Acid Sequence; Animals; Cells, Cultured; Colon; Dose-Response Relationship, Drug; Female; Glicentin; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Male; Middle Aged; Molecular Sequence Data; Muscle Contraction; Muscle, Smooth; Peptide Fragments; Protein Precursors; Sequence Homology, Amino Acid | 2005 |
Coexistence of gastric- and intestinal-type endocrine cells in gastric and intestinal mixed intestinal metaplasia of the human stomach.
Topics: Aged; Chromogranin A; Chromogranins; Endocrine Glands; Female; Gastric Fundus; Gastric Inhibitory Polypeptide; Gastric Mucosa; Gastrins; Glicentin; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Immunohistochemistry; Intestines; Male; Metaplasia; Middle Aged; Peptide Fragments; Protein Precursors; Pyloric Antrum; Somatostatin; Stomach Neoplasms | 2005 |
Mucosal adaptation to enteral nutrients is dependent on the physiologic actions of glucagon-like peptide-2 in mice.
Topics: Adaptation, Physiological; Amino Acid Sequence; Animals; Apoptosis; Body Weight; Cell Division; Cloning, Molecular; Drinking; Eating; Female; Gene Expression; Glucagon; Glucagon-Like Peptide 2; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Intestinal Mucosa; Intestine, Small; Male; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Organ Size; Peptide Fragments; Proglucagon; Protein Precursors; Rats; Rats, Wistar; Receptors, Glucagon | 2005 |
Involvement of endogenous glucagon-like peptide-1(7-36) amide on glycaemia-lowering effect of oligofructose in streptozotocin-treated rats.
Topics: Actins; Animals; Blood Glucose; Colon; Diabetes Mellitus, Experimental; Eating; Fermentation; Food Deprivation; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Tolerance Test; Insulin; Islets of Langerhans; Male; Oligosaccharides; Peptide Fragments; Proglucagon; Proprotein Convertase 1; Protein Precursors; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2005 |
Active metabolite of GLP-1 mediates myocardial glucose uptake and improves left ventricular performance in conscious dogs with dilated cardiomyopathy.
Topics: Animals; Blood Pressure; Cardiomyopathy, Dilated; Consciousness; Coronary Circulation; Dogs; Dose-Response Relationship, Drug; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Heart; Heart Ventricles; Male; Myocardium; Peptide Fragments; Peptides; Stroke Volume; Treatment Outcome; Ventricular Dysfunction, Left | 2005 |
Mitogenic influence of human R-spondin1 on the intestinal epithelium.
Topics: Animals; Antineoplastic Agents; beta Catenin; Cell Line; Cell Line, Tumor; Cell Proliferation; Chimera; Colon; Cytoskeletal Proteins; Dose-Response Relationship, Drug; Enteroendocrine Cells; Epithelial Cells; Fibroblast Growth Factor 7; Fibroblast Growth Factors; Fluorouracil; Glucagon-Like Peptides; Humans; Intestinal Mucosa; Intestine, Small; Mice; Mice, Transgenic; Mitogens; Neoplasm Transplantation; Neoplasms, Experimental; Peptides; Proteins; Recombinant Proteins; Thrombospondins; Tongue; Trans-Activators; Wnt Proteins; Wnt3 Protein | 2005 |
Glucagon-like peptide-1 reduces the pulsatile component of testosterone secretion in healthy males.
Topics: Administration, Oral; Adult; Blood Glucose; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glucose Clamp Technique; Glucose Tolerance Test; Humans; Infusions, Intravenous; Insulin; Leptin; Luteinizing Hormone; Male; Peptide Fragments; Testosterone | 2005 |
Hormonal regulation of leptin receptor expression in primary cultures of porcine hepatocytes.
Topics: Animals; Cyclic AMP; Ghrelin; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Hepatocytes; Insulin; Liver Glycogen; Male; Peptide Fragments; Peptide Hormones; Protein Isoforms; Receptors, Cell Surface; Receptors, Leptin; Reverse Transcriptase Polymerase Chain Reaction; RNA; Triiodothyronine; Up-Regulation | 2005 |
Human duodenal enteroendocrine cells: source of both incretin peptides, GLP-1 and GIP.
Topics: Adult; Aged; Aged, 80 and over; Area Under Curve; Biopsy; Diabetes Mellitus, Type 2; Duodenum; Enteroendocrine Cells; Enzyme-Linked Immunosorbent Assay; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glucose Tolerance Test; Humans; Immunohistochemistry; Insulin; Insulin Resistance; Male; Middle Aged; Peptide Fragments; Reverse Transcriptase Polymerase Chain Reaction | 2006 |
Plasma concentrations of glucagon-like peptide-2 in adult patients with treated and untreated coeliac disease.
Topics: Adult; Celiac Disease; Female; Follow-Up Studies; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Glutens; Humans; Male; Middle Aged; Radioimmunoassay; Treatment Outcome | 2006 |
Glucagon-like peptide 2 stimulates glucagon secretion, enhances lipid absorption, and inhibits gastric acid secretion in humans.
Topics: Adult; Fasting; Fatty Acids; Gastric Acid; Gastric Emptying; Glucagon; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Humans; Hypoglycemic Agents; Infusions, Intravenous; Insulin; Lipid Metabolism; Male; Placebos; Postprandial Period | 2006 |
Direct effects of glucagon-like peptide-1 on myocardial contractility and glucose uptake in normal and postischemic isolated rat hearts.
Topics: Animals; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glucose Transporter Type 1; Heart; In Vitro Techniques; Male; Myocardial Contraction; Myocardial Ischemia; Myocardium; Nitric Oxide; Peptide Fragments; Protein Transport; Rats; Rats, Wistar; Ventricular Function, Left | 2006 |
Transcription factor FoxO1 mediates glucagon-like peptide-1 effects on pancreatic beta-cell mass.
Topics: Animals; Cell Division; Cell Line; Cell Survival; Forkhead Box Protein O1; Forkhead Transcription Factors; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Green Fluorescent Proteins; Insulin; Islets of Langerhans; Mice; Mice, Transgenic; Peptide Fragments | 2006 |
Glucagon-related peptides in the mouse retina and the effects of deprivation of form vision.
Topics: Animals; Disease Models, Animal; Early Growth Response Protein 1; Fluorescent Antibody Technique, Indirect; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptides; Growth Hormone-Releasing Hormone; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence; Myopia; Peptide PHI; Pituitary Adenylate Cyclase-Activating Polypeptide; Retina; Sensory Deprivation; Vasoactive Intestinal Peptide | 2007 |
Oxyntomodulin increases intrinsic heart rate in mice independent of the glucagon-like peptide-1 receptor.
Topics: Animals; Autonomic Nervous System; Blood Pressure; Body Temperature; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Dopamine beta-Hydroxylase; Dose-Response Relationship, Drug; Eating; Electrocardiography; Epinephrine; Exenatide; Female; Glucagon; Glucagon-Like Peptide-1 Receptor; Heart; Heart Rate; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Norepinephrine; Oxyntomodulin; Peptides; Rats; Rats, Sprague-Dawley; Receptors, Glucagon; Telemetry; Venoms | 2007 |
Oxyntomodulin differentially affects glucagon-like peptide-1 receptor beta-arrestin recruitment and signaling through Galpha(s).
Topics: Animals; Arrestins; beta-Adrenergic Receptor Kinases; beta-Arrestins; Chlorocebus aethiops; COS Cells; Cyclic AMP; G-Protein-Coupled Receptor Kinase 2; G-Protein-Coupled Receptor Kinase 5; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; GTP-Binding Protein alpha Subunits, Gs; Humans; Luminescent Measurements; Oxyntomodulin; Protein Serine-Threonine Kinases; Receptors, Glucagon; Signal Transduction | 2007 |
Direct visualisation of peptide hormones in cultured pancreatic islet alpha- and beta-cells by intact-cell mass spectrometry.
Topics: Animals; Cell Line; Coumaric Acids; Glucagon; Glucagon-Secreting Cells; Insulin; Insulin-Secreting Cells; Microscopy, Electron, Scanning; Oxyntomodulin; Peptide Mapping; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2007 |
Inappropriate glucagon response after oral compared with isoglycemic intravenous glucose administration in patients with type 1 diabetes.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptides; Glucose; Glucose Tolerance Test; Humans; Infusions, Intravenous; Male; Young Adult | 2010 |
Oxyntomodulin increases the concentrations of insulin and glucose in plasma but does not affect ghrelin secretion in Holstein cattle under normal physiological conditions.
Topics: Amino Acid Sequence; Animals; Blood Glucose; Cattle; Fatty Acids, Nonesterified; Ghrelin; Glucagon; Insulin; Male; Molecular Sequence Data; Oxyntomodulin; Secretin | 2010 |
[Pancreatic glucagon (IRG), enteroglucagon (EG)].
Topics: Diabetes Mellitus; Glucagon; Glucagon-Like Peptides; Humans; Pancreas; Pancreatitis, Chronic | 2010 |
Glucagon-like peptide-1 inhibits insulinotropic effects of oxyntomodulin and glucagon in cattle.
Topics: Animals; Blood Glucose; Cattle; Glucagon; Glucagon-Like Peptide 1; Insulin; Intercellular Signaling Peptides and Proteins; Male; Oxyntomodulin; Peptides | 2012 |
The glucagon receptor is involved in mediating the body weight-lowering effects of oxyntomodulin.
Topics: Animals; Anti-Obesity Agents; Energy Intake; Glucagon; Glucagon-Like Peptide-1 Receptor; Glycogenolysis; Humans; Hypoglycemic Agents; Hypolipidemic Agents; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Obese; Obesity; Oxyntomodulin; Receptors, Glucagon; Weight Loss | 2012 |
Direct control of brown adipose tissue thermogenesis by central nervous system glucagon-like peptide-1 receptor signaling.
Topics: Adipose Tissue, Brown; Animals; Central Nervous System; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Insulin Resistance; Ion Channels; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondrial Proteins; Nerve Tissue Proteins; Neurons; Oxyntomodulin; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Receptors, Glucagon; Scapula; Signal Transduction; Sympathetic Nervous System; Thermogenesis; Trans-Activators; Transcription Factors; Uncoupling Protein 1; Up-Regulation | 2012 |
Intracerebroventricular administration of novel glucagon-like peptide suppresses food intake in chicks.
Topics: Animals; Appetite Depressants; Blood Glucose; Brain; Chickens; Corticosterone; Eating; Glucagon; Glucagon-Like Peptide 1; Incretins; Male; Oxyntomodulin; Receptors, Corticotropin-Releasing Hormone | 2014 |
Specificity and sensitivity of commercially available assays for glucagon and oxyntomodulin measurement in humans.
Topics: Diabetes Mellitus, Type 2; Enzyme-Linked Immunosorbent Assay; Glucagon; Humans; Oxyntomodulin; Radioimmunoassay; Sensitivity and Specificity | 2014 |
Comparison of stability, cellular, glucose-lowering and appetite supressing effects of oxyntomodulin analogues modified at the N-terminus.
Topics: Animals; Appetite; Blood Glucose; Cyclic AMP; Dipeptidyl Peptidase 4; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucose; Half-Life; Hypoglycemic Agents; Insulin; Male; Mice; Mice, Inbred C57BL; Oxyntomodulin; Peptides; Receptors, Glucagon | 2014 |
Deciphering metabolic messages from the gut drives therapeutic innovation: the 2014 Banting Lecture.
Topics: Animals; Awards and Prizes; Canada; Diabetes Mellitus; Gastrointestinal Tract; Glucagon; Glucagon-Like Peptides; History, 21st Century; Hormones; Humans; Insulin; Mice; Societies, Medical; United States | 2015 |
Sustained treatment with a stable long-acting oxyntomodulin analogue improves metabolic control and islet morphology in an experimental model of type 1 diabetes.
Topics: Animals; Apoptosis; Blood Glucose; Cell Proliferation; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Eating; Gastrointestinal Hormones; Glucagon; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Islets of Langerhans; Mice; Oxyntomodulin; Pancreas | 2015 |
Degradation and Stabilization of Peptide Hormones in Human Blood Specimens.
Topics: Amino Acid Sequence; Dipeptidyl Peptidase 4; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Humans; Incretins; Molecular Sequence Data; Oxyntomodulin; Peptide Fragments; Peptide Hormones; Protein Stability; Proteolysis; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2015 |
Multiplexed Quantification of Proglucagon-Derived Peptides by Immunoaffinity Enrichment and Tandem Mass Spectrometry after a Meal Tolerance Test.
Topics: Animals; Chromatography, High Pressure Liquid; Fasting; Glucagon; Glucagon-Like Peptide 1; Humans; Immunoassay; Mice; Mice, Inbred BALB C; Oxyntomodulin; Tandem Mass Spectrometry | 2016 |
Proglucagon-Derived Peptides Do Not Significantly Affect Acute Exocrine Pancreas in Rats.
Topics: Actins; Amylases; Animals; Cell Line, Tumor; Cells, Cultured; Exenatide; Gene Expression; Glucagon; Glucagon-Like Peptide 1; Injections, Intravenous; Ki-67 Antigen; Male; Oxyntomodulin; Pancreas, Exocrine; Peptides; Proglucagon; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Venoms | 2016 |
Dulaglutide (LY-2189265) for the treatment of type 2 diabetes.
Topics: Adult; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Glucagon; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Humans; Hyperglycemia; Hypoglycemic Agents; Immunoglobulin Fc Fragments; Insulin; Insulin Secretion; Recombinant Fusion Proteins | 2016 |
Differential effects of once-weekly glucagon-like peptide-1 receptor agonist dulaglutide and metformin on pancreatic β-cell and insulin sensitivity during a standardized test meal in patients with type 2 diabetes.
Topics: Adult; Aged; Area Under Curve; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Fasting; Female; Glucagon; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Immunoglobulin Fc Fragments; Insulin; Insulin Resistance; Insulin-Secreting Cells; Male; Metformin; Middle Aged; Postprandial Period; Recombinant Fusion Proteins; Treatment Outcome | 2016 |
Measurement of Gastrointestinal Hormones.
Topics: Bariatric Surgery; Diabetes Mellitus, Type 2; Glucagon; Glucagon-Like Peptide 1; Humans; Mass Spectrometry; Neuropeptides; Obesity; Oxyntomodulin; Specimen Handling | 2017 |
Oxyntomodulin analogue increases energy expenditure via the glucagon receptor.
Topics: Animals; Calorimetry, Indirect; Energy Metabolism; Glucagon; Male; Oxyntomodulin; Peptide Fragments; Rats; Rats, Wistar; Receptors, Glucagon | 2018 |
Cellular and sub-cellular localisation of oxyntomodulin-like immunoreactivity in enteroendocrine cells of human, mouse, pig and rat.
Topics: Amino Acid Sequence; Animals; Antibodies; Colon; Enteroendocrine Cells; Female; Glucagon; Humans; Jejunum; Male; Mice, Inbred C57BL; Organ Specificity; Oxyntomodulin; Peptides; Protein Transport; Rats; Species Specificity; Subcellular Fractions; Swine | 2019 |
Gut Hormone Responses to Mixed Meal Test in New-Onset Prediabetes/Diabetes After Acute Pancreatitis.
Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Female; Gastric Inhibitory Polypeptide; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Humans; Insulin; Magnetic Resonance Imaging; Male; Meals; Middle Aged; Oxyntomodulin; Pancreatitis; Peptide YY; Postprandial Period; Prediabetic State; Subcutaneous Fat | 2019 |
Novel glucagon- and OXM-based peptides acting through glucagon and GLP-1 receptors with body weight reduction and anti-diabetic properties.
Topics: Amino Acid Sequence; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Energy Intake; Glucagon; Glucagon-Like Peptide-1 Receptor; Glucose Tolerance Test; Hypoglycemic Agents; Mice; Obesity; Oxyntomodulin; Peptides; Sequence Homology, Amino Acid; Streptozocin; Structure-Activity Relationship; Weight Loss | 2020 |
Comparison of the glucagon-like-peptide-1 receptor agonists dulaglutide and liraglutide for the management of diabetes in solid organ transplant: A retrospective study.
Topics: Adult; Diabetes Mellitus, Type 2; Glucagon; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Immunoglobulin Fc Fragments; Liraglutide; Organ Transplantation; Recombinant Fusion Proteins; Retrospective Studies | 2020 |
Design and characterization of novel oxyntomodulin derivatives with potent dual GLP-1/glucagon receptor activation and prolonged antidiabetic effects.
Topics: Animals; Blood Glucose; Diabetes Mellitus; Dimerization; Glucagon; Glucagon-Like Peptide-1 Receptor; Glucose Tolerance Test; Hypoglycemic Agents; Macaca fascicularis; Male; Mice; Mice, Knockout; Mice, Obese; Obesity; Oxyntomodulin; Polyethylene Glycols; Rats, Sprague-Dawley; Receptors, Glucagon; Solid-Phase Synthesis Techniques; Weight Loss | 2020 |
Deficiency of glucagon gene-derived peptides induces peripheral polyneuropathy in mice.
Topics: Animals; Diabetic Neuropathies; Disease Models, Animal; Ganglia, Spinal; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Hyperalgesia; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Fibers, Myelinated; Neural Conduction; Neuronal Outgrowth; Receptors, Glucagon; RNA, Messenger | 2020 |
S3-2, a novel long-lasting oxyntomodulin derivative, exerts improvement on diabesity and renal injury through activating GLP-1 and glucagon receptors.
Topics: Albumins; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucose; Hypoglycemic Agents; Insulin; Kidney; Male; Mice; Mice, Inbred C57BL; Obesity; Oxyntomodulin; Peptides; Receptors, Glucagon | 2021 |
Thermo-Responsive self-assembly of a dual glucagon-like peptide and glucagon receptor agonist.
Topics: Diabetes Mellitus, Type 2; Glucagon; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Humans; Pharmaceutical Preparations; Receptors, Glucagon | 2021 |
Effects of glucagon-like peptide-1 receptor agonists on secretions of insulin and glucagon and gastric emptying in Japanese individuals with type 2 diabetes: A prospective, observational study.
Topics: Adult; Apolipoprotein B-48; Blood Glucose; Diabetes Mellitus, Type 2; Female; Gastric Emptying; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Humans; Hypoglycemic Agents; Immunoglobulin Fc Fragments; Insulin; Japan; Liraglutide; Male; Middle Aged; Peptides; Postprandial Period; Prospective Studies; Recombinant Fusion Proteins | 2021 |
Mutational Landscape of the Proglucagon-Derived Peptides.
Topics: Amino Acid Sequence; Datasets as Topic; DNA Mutational Analysis; Gene Frequency; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Humans; Models, Molecular; Mutation, Missense; Pharmacogenomic Testing; Proglucagon; Protein Precursors; Protein Structure, Secondary | 2021 |
Development of a selective, sensitive and robust oxyntomodulin dual monoclonal antibody immunoassay.
Topics: Antibodies, Monoclonal; Glucagon; Glucagon-Like Peptide 1; Humans; Immunoassay; Oxyntomodulin; Proglucagon; Protein Precursors | 2022 |
Circulating levels of proglucagon-derived peptides are differentially regulated by the glucagon-like peptide-1 agonist liraglutide and the centrally acting naltrexone/bupropion and can predict future weight loss and metabolic improvements: A 6-month long
Topics: Bupropion; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Humans; Liraglutide; Naltrexone; Obesity; Overweight; Peptides; Proglucagon; Weight Loss | 2023 |
Self-assembled GLP-1/glucagon peptide nanofibrils prolong inhibition of food intake.
Topics: Animals; Eating; Glucagon; Glucagon-Like Peptide 1; Oxyntomodulin; Peptide Hydrolases; Peptides; Receptors, Glucagon | 2023 |