Page last updated: 2024-09-04

glucagon and orlistat

glucagon has been researched along with orlistat in 6 studies

Compound Research Comparison

Studies
(glucagon)
Trials
(glucagon)
Recent Studies (post-2010)
(glucagon)
Studies
(orlistat)
Trials
(orlistat)
Recent Studies (post-2010) (orlistat)
26,0391,4983,0541,432274539

Protein Interaction Comparison

ProteinTaxonomyglucagon (IC50)orlistat (IC50)
Phosphatidylserine lipase ABHD16AHomo sapiens (human)0.1
Pancreatic triacylglycerol lipaseSus scrofa (pig)0.4214
Lipoprotein lipaseHomo sapiens (human)0.066
Cytochrome P450 3A4Homo sapiens (human)0.42
Hepatic triacylglycerol lipaseHomo sapiens (human)0.003
Pancreatic triacylglycerol lipaseHomo sapiens (human)0.3253
Translocator proteinRattus norvegicus (Norway rat)1
Cytochrome P450 2C19Homo sapiens (human)0.42
Kappa-type opioid receptorMus musculus (house mouse)0.1903
Fatty acid synthaseHomo sapiens (human)2.99
Fatty-acid amide hydrolase 1Rattus norvegicus (Norway rat)0.01
Platelet-activating factor acetylhydrolaseHomo sapiens (human)0.05
Diacylglycerol lipase-alphaMus musculus (house mouse)0.02
Lysophosphatidylserine lipase ABHD12Homo sapiens (human)0.1682
Diacylglycerol lipase-betaHomo sapiens (human)0.24
Monoacylglycerol lipase ABHD6Homo sapiens (human)0.03
Acyl-protein thioesterase 2Rattus norvegicus (Norway rat)0.17
Diacylglycerol lipase-alphaHomo sapiens (human)0.2677
Endothelial lipaseHomo sapiens (human)0.006

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Boyd, AE; Civelek, VN; Corkey, BE; Deeney, JT; Dillon, JS; Hamilton, JA; Korchak, HM; Richard, AM; Tornheim, K; Yaney, GC1
Bryant, L; Feinle, C; Horowitz, M; Jones, KL; Lei, Y; Meyer, JH; O'Donovan, D; Pilichiewicz, A; Wishart, JM1
Balci, H; Damci, T; Ilkova, H; Korugan, U; Osar, Z; Ozyazar, M; Yalin, S1
Feinle-Bisset, C; Horowitz, M; Jones, K; Nauck, M1
Ballaux, D; Mertens, I; Van Gaal, L; Verkade, HJ1
Feinle-Bisset, C; Gentilcore, D; Horowitz, M; Jones, KL; Morris, HA; Murolo, N; O'Donovan, D; Russo, A; Wishart, JM1

Reviews

1 review(s) available for glucagon and orlistat

ArticleYear
Modern, new pharmacotherapy for obesity. A gastrointestinal approach.
    Best practice & research. Clinical gastroenterology, 2004, Volume: 18, Issue:6

    Topics: Amylases; Androgens; Anti-Obesity Agents; Citrates; Cyclobutanes; Dietary Fats; Fat Substitutes; Fatty Acids; Glucagon; Glucagon-Like Peptide 1; Glucosidases; Human Growth Hormone; Humans; Intestinal Absorption; Lactones; Lipase; Obesity; Orlistat; Peptide Fragments; Protein Precursors; Sucrose

2004

Trials

2 trial(s) available for glucagon and orlistat

ArticleYear
Effect of lipase inhibition on gastric emptying of, and the glycemic and incretin responses to, an oil/aqueous drink in type 2 diabetes mellitus.
    The Journal of clinical endocrinology and metabolism, 2003, Volume: 88, Issue:8

    Topics: Autonomic Nervous System; Blood Glucose; Diabetes Mellitus, Type 2; Dietary Fats; Enzyme Inhibitors; Female; Gastric Emptying; Gastric Inhibitory Polypeptide; Gastric Mucosa; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Hemodynamics; Humans; Insulin; Lactones; Lipase; Male; Middle Aged; Orlistat; Peptide Fragments; Peptides

2003
Orlistat augments postprandial increases in glucagon-like peptide 1 in obese type 2 diabetic patients.
    Diabetes care, 2004, Volume: 27, Issue:5

    Topics: Adult; Aged; Anti-Obesity Agents; Cross-Over Studies; Diabetes Mellitus; Diabetes Mellitus, Type 2; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Humans; Insulin; Lactones; Male; Middle Aged; Obesity; Orlistat; Peptide Fragments; Protein Precursors; Single-Blind Method; Weight Loss

2004

Other Studies

3 other study(ies) available for glucagon and orlistat

ArticleYear
Glucagon-like peptide 1 stimulates lipolysis in clonal pancreatic beta-cells (HIT).
    Diabetes, 2001, Volume: 50, Issue:1

    Topics: Calcium; Cell Line; Enzyme Inhibitors; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Hydrogen-Ion Concentration; Intracellular Membranes; Islets of Langerhans; Lactones; Lipase; Lipolysis; Orlistat; Peptide Fragments; Protein Precursors; Sterol Esterase

2001
Orlistat augments postprandial increases in glucagon-like peptide-1 in obese type 2 diabetic patients: response to Damci et al.
    Diabetes care, 2004, Volume: 27, Issue:11

    Topics: Anti-Obesity Agents; Diabetes Mellitus, Type 2; Glucagon; Glucagon-Like Peptide 1; Humans; Lactones; Obesity; Orlistat; Peptide Fragments; Postprandial Period; Protein Precursors

2004
Effects of lipase inhibition on gastric emptying of, and on the glycaemic, insulin and cardiovascular responses to, a high-fat/carbohydrate meal in type 2 diabetes.
    Diabetologia, 2004, Volume: 47, Issue:12

    Topics: Aged; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 2; Dietary Carbohydrates; Dietary Fats; Enzyme Inhibitors; Female; Gastric Emptying; Glucagon; Glucagon-Like Peptide 1; Heart Rate; Humans; Insulin; Insulin Secretion; Lactones; Lipase; Male; Middle Aged; Orlistat; Peptide Fragments; Protein Precursors

2004