Page last updated: 2024-09-04

glucagon and olanzapine

glucagon has been researched along with olanzapine in 7 studies

Compound Research Comparison

Studies
(glucagon)
Trials
(glucagon)
Recent Studies (post-2010)
(glucagon)
Studies
(olanzapine)
Trials
(olanzapine)
Recent Studies (post-2010) (olanzapine)
26,0391,4983,0546,3391,3402,383

Protein Interaction Comparison

ProteinTaxonomyglucagon (IC50)olanzapine (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.097
Muscarinic acetylcholine receptor M4Homo sapiens (human)0.155
5-hydroxytryptamine receptor 2CRattus norvegicus (Norway rat)0.047
Muscarinic acetylcholine receptor M5Homo sapiens (human)0.04
Alpha-2A adrenergic receptorHomo sapiens (human)0.541
Polyunsaturated fatty acid lipoxygenase ALOX15Oryctolagus cuniculus (rabbit)2.768
D(2) dopamine receptorHomo sapiens (human)0.118
5-hydroxytryptamine receptor 2ARattus norvegicus (Norway rat)0.047
Alpha-2B adrenergic receptorHomo sapiens (human)0.421
Alpha-2C adrenergic receptorHomo sapiens (human)0.531
Muscarinic acetylcholine receptor M3Homo sapiens (human)0.392
D(1A) dopamine receptorHomo sapiens (human)0.072
D(4) dopamine receptorHomo sapiens (human)0.173
Alpha-1D adrenergic receptorHomo sapiens (human)0.092
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.038
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.021
5-hydroxytryptamine receptor 2BRattus norvegicus (Norway rat)0.047
Sodium-dependent serotonin transporterHomo sapiens (human)1.033
Histamine H1 receptorHomo sapiens (human)0.013
D(3) dopamine receptorHomo sapiens (human)0.078
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.057
5-hydroxytryptamine receptor 6Homo sapiens (human)0.013
D(2) dopamine receptorRattus norvegicus (Norway rat)0.158
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)0.2028

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (14.29)18.2507
2000's1 (14.29)29.6817
2010's4 (57.14)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Joye, F; Marion, F; Michoux, I; Orrillard, M; Parisot, R1
Baptista, T; Beaulieu, S; Contreras, Q; de Mendoza, S; Galeazzi, T; Lacruz, A; Rangel, N; Sandia, I; Vargas, D1
Shepherd, PR; Smith, GC; Vickers, MH1
Ikeda, H; Ikegami, M; Ishikawa, Y; Kai, M; Kamei, A; Kamei, J; Ohashi, T; Ohsawa, M1
Ishiwata, Y; Nagata, M; Nakajima, M; Negishi, K; Takahashi, H; Takahashi, Y; Yasuhara, M1
Castellani, LN; Charron, MJ; Peppler, WT; Sutton, CD; Whitfield, J; Wright, DC1
Hahn, MK; McKie, GL; Medak, KD; Shamshoum, H; Wright, DC1

Trials

1 trial(s) available for glucagon and olanzapine

ArticleYear
Insulin counter-regulatory factors, fibrinogen and C-reactive protein during olanzapine administration: effects of the antidiabetic metformin.
    International clinical psychopharmacology, 2007, Volume: 22, Issue:2

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Blood Glucose; C-Reactive Protein; Double-Blind Method; Female; Fibrinogen; Glucagon; Human Growth Hormone; Humans; Hydrocortisone; Hypoglycemic Agents; Insulin; Insulin Resistance; Leptin; Male; Metabolic Syndrome; Metformin; Middle Aged; Olanzapine; Schizophrenia; Sex Factors; Treatment Outcome; Tumor Necrosis Factor-alpha

2007

Other Studies

6 other study(ies) available for glucagon and olanzapine

ArticleYear
[Severe intoxication probably from olanzapine (Zyprexa). Beneficial effect of glucagon].
    Annales francaises d'anesthesie et de reanimation, 1999, Volume: 18, Issue:6

    Topics: Adult; Alprazolam; Antipsychotic Agents; Benzodiazepines; Bradycardia; Carbamazepine; Disseminated Intravascular Coagulation; Drug Therapy, Combination; Gastrointestinal Agents; Glucagon; Humans; Hypothermia; Infusions, Intravenous; Male; Methotrimeprazine; Olanzapine; Pirenzepine; Schizophrenia; Shock

1999
Olanzapine effects on body composition, food preference, glucose metabolism and insulin sensitivity in the rat.
    Archives of physiology and biochemistry, 2011, Volume: 117, Issue:4

    Topics: Animals; Antipsychotic Agents; Benzodiazepines; Body Composition; Body Weight; Diet, High-Fat; Food Preferences; Glucagon; Glucagon-Like Peptide 1; Glucose; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Liver; Male; Obesity; Olanzapine; Rats; Schizophrenia; Weight Gain

2011
Olanzapine induces glucose intolerance through the activation of AMPK in the mouse hypothalamus.
    European journal of pharmacology, 2013, Oct-15, Volume: 718, Issue:1-3

    Topics: AMP-Activated Protein Kinases; Animals; Benzodiazepines; Enzyme Activation; Glucagon; Glucose; Glucose Tolerance Test; Homeostasis; Hypothalamus; Insulin; Male; Mice; Mice, Inbred ICR; Olanzapine; Phosphorylation; Protein Kinase Inhibitors

2013
Mechanism Underlying Induction of Hyperglycemia in Rats by Single Administration of Olanzapine.
    Biological & pharmaceutical bulletin, 2016, Volume: 39, Issue:5

    Topics: Animals; Antipsychotic Agents; Benzodiazepines; Blood Glucose; Corticosterone; Epinephrine; Glucagon; Histamine; Hyperglycemia; Injections, Intravenous; Insulin; Male; Models, Biological; Olanzapine; Propranolol; Rats, Wistar

2016
Glucagon receptor knockout mice are protected against acute olanzapine-induced hyperglycemia.
    Psychoneuroendocrinology, 2017, Volume: 82

    Topics: Animals; Benzodiazepines; Blood Glucose; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucose; Glucose Tolerance Test; Homeostasis; Hyperglycemia; Insulin; Liver; Mice; Mice, Inbred C57BL; Mice, Knockout; Olanzapine; Receptors, Glucagon

2017
Fasting or the short-term consumption of a ketogenic diet protects against antipsychotic-induced hyperglycaemia in mice.
    The Journal of physiology, 2022, Volume: 600, Issue:11

    Topics: 3-Hydroxybutyric Acid; Animals; Antipsychotic Agents; Blood Glucose; Diet, Ketogenic; Esters; Fasting; Glucagon; Hyperglycemia; Insulin; Ketone Bodies; Ketones; Mice; Olanzapine

2022