Page last updated: 2024-09-04

glucagon and ng-nitroarginine methyl ester

glucagon has been researched along with ng-nitroarginine methyl ester in 27 studies

Compound Research Comparison

Studies
(glucagon)
Trials
(glucagon)
Recent Studies (post-2010)
(glucagon)
Studies
(ng-nitroarginine methyl ester)
Trials
(ng-nitroarginine methyl ester)
Recent Studies (post-2010) (ng-nitroarginine methyl ester)
26,0391,4983,05412,6401172,342

Protein Interaction Comparison

ProteinTaxonomyglucagon (IC50)ng-nitroarginine methyl ester (IC50)
Neutrophil elastaseHomo sapiens (human)2.7
Nitric oxide synthase, endothelialHomo sapiens (human)2.1
Nitric oxide synthase, brainHomo sapiens (human)1.1167
Nitric oxide synthase, inducibleMus musculus (house mouse)2.6
Nitric oxide synthase, inducibleHomo sapiens (human)8
Collagenase 3Homo sapiens (human)2.7

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's16 (59.26)18.2507
2000's10 (37.04)29.6817
2010's1 (3.70)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tolins, JP1
Bjerre, U; Mandrup-Poulsen, T; Nerup, J; Reimers, JI1
Bernadich, C; Bosch, J; Fernández, M; García-Pagán, JC; Piqué, JM; Pizcueta, P; Rodés, J1
Carlberg, M; Henningson, R; Lundquist, I; Salehi, A1
Akesson, B; Lundquist, I; Mosén, H; Panagiotidis, G1
Caffarri, G; Capretti, L; Chiodera, P; Coiro, V; Speroni, G; Volpi, R1
Bloom, SR; Edwards, AV; Edwards, CM1
Lundquist, I; Parandeh, F; Salehi, A2
Henningsson, R; Lundquist, I1
Akesson, B; Lundquist, I2
Aring;kesson, B; Lundquist, I1
Akesson, B; Henningsson, R; Lundquist, I; Salehi, A1
Bandi, JC; Bernadich, C; Bosch, J; De Lacy, AM; Fernández, M; García-Pagán, JC; Rodés, J1
Bloom, SR; Edwards, AV; Edwards, CM; Ghatei, MA1
Alm, P; Henningsson, R; Lindström, E; Lundquist, I1
Alm, P; Henningsson, R; Lundquist, I1
Hamaguchi, K; Kato, Y; Koshimura, K; Mori, T; Murakami, Y1
Chang, FY; Hou, MC; Huang, YT; Lee, FY; Lee, SD; Lee, TY; Lee, WC; Lin, HC; Yang, YY1
Russell, WE; Scheving, LA1
Feddersen, CO; Golpon, HA; Puechner, A; Welte, T; Wichert, PV1
Jimenez-Feltstrom, J; Lundquist, I; Obermuller, S; Salehi, A1
Jimenez-Feltstrom, J; Lundquist, I; Salehi, A1
Ekelund, M; Håkanson, R; Lundquist, I; Qader, SS; Salehi, A1
Efendic, S; Jimenez-Feltstrom, J; Lundquist, I; Meidute Abaraviciene, S; Ostenson, CG; Salehi, A1
Charron, MJ; Dean, ED; Vuguin, PM1

Trials

1 trial(s) available for glucagon and ng-nitroarginine methyl ester

ArticleYear
Involvement of nitric oxide in arginine, but not glucose, induced insulin secretion in normal men.
    Clinical endocrinology, 1997, Volume: 46, Issue:1

    Topics: Adult; Arginine; Glucagon; Glucose; Humans; Insulin; Insulin Secretion; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase

1997

Other Studies

26 other study(ies) available for glucagon and ng-nitroarginine methyl ester

ArticleYear
Mechanisms of glucagon-induced renal vasodilation: role of prostaglandins and endothelium-derived relaxing factor.
    The Journal of laboratory and clinical medicine, 1992, Volume: 120, Issue:6

    Topics: Animals; Arginine; Glomerular Filtration Rate; Glucagon; Indomethacin; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Prostaglandins; Rats; Rats, Sprague-Dawley; Renal Circulation; Vasodilation

1992
Interleukin 1 beta induces diabetes and fever in normal rats by nitric oxide via induction of different nitric oxide synthases.
    Cytokine, 1994, Volume: 6, Issue:5

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Glucose; Body Temperature; Body Weight; Corticosterone; Diabetes Mellitus, Experimental; Glucagon; Guanidines; Humans; Insulin; Interleukin-1; Isoenzymes; Leukocyte Count; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Inbred WKY; Recombinant Proteins; Weight Gain

1994
Effects of continued NO inhibition on portal hypertensive syndrome after portal vein stenosis in rat.
    The American journal of physiology, 1994, Volume: 267, Issue:6 Pt 1

    Topics: Animals; Arginine; Glucagon; Hematocrit; Hemodynamics; Hypertension, Portal; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Portal Vein; Rats; Rats, Sprague-Dawley; Splanchnic Circulation

1994
Islet constitutive nitric oxide synthase: biochemical determination and regulatory function.
    The American journal of physiology, 1996, Volume: 270, Issue:6 Pt 1

    Topics: Animals; Arginine; Enzyme Inhibitors; Female; Glucagon; Glucose; Hydroxylamine; Hydroxylamines; In Vitro Techniques; Insulin; Islets of Langerhans; Mice; Mice, Inbred Strains; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Osmolar Concentration

1996
Interaction of the islet nitric oxide system with L-arginine-induced secretion of insulin and glucagon in mice.
    British journal of pharmacology, 1996, Volume: 119, Issue:4

    Topics: Animals; Arginine; Enzyme Inhibitors; Glucagon; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase

1996
Cardiovascular and pancreatic endocrine responses to glucagon-like peptide-1(7-36) amide in the conscious calf.
    Experimental physiology, 1997, Volume: 82, Issue:4

    Topics: Amino Acids; Animals; Blood Glucose; Blood Pressure; Cattle; Enzyme Inhibitors; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Heart Rate; Insulin; Insulin Secretion; Islets of Langerhans; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroprusside; Pancreatic Polypeptide; Peptide Fragments

1997
The nitric oxide synthase inhibitor NG-nitro-L-arginine methyl ester potentiates insulin secretion stimulated by glucose and L-arginine independently of its action on ATP-sensitive K+ channels.
    Bioscience reports, 1998, Volume: 18, Issue:1

    Topics: Adenosine Triphosphate; Animals; Arginine; Diazoxide; Enzyme Inhibitors; Female; Glucagon; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Potassium Channels

1998
Arginine-induced insulin release is decreased and glucagon increased in parallel with islet NO production.
    The American journal of physiology, 1998, Volume: 275, Issue:3

    Topics: Animals; Arginine; Diazoxide; Dose-Response Relationship, Drug; Female; Glucagon; Homoarginine; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Mice; Mice, Inbred Strains; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; omega-N-Methylarginine

1998
Signal transduction in islet hormone release: interaction of nitric oxide with basal and nutrient-induced hormone responses.
    Cellular signalling, 1998, Volume: 10, Issue:9

    Topics: Animals; Caproates; Diazoxide; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Glucagon; Glucose; Hydroxylamine; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Potassium; Signal Transduction

1998
Evidence for nitric oxide mediated effects on islet hormone secretory phospholipase C signal transduction mechanisms.
    Bioscience reports, 1998, Volume: 18, Issue:4

    Topics: Animals; Calcium; Carbachol; Cell Membrane; Cholinergic Agonists; Diazoxide; Enzyme Inhibitors; Female; Glucagon; Hydroxylamine; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Potassium Channels; Receptors, Muscarinic; Signal Transduction; Tetradecanoylphorbol Acetate; Type C Phospholipases

1998
Influence of nitric oxide modulators on cholinergically stimulated hormone release from mouse islets.
    The Journal of physiology, 1999, Mar-01, Volume: 515 ( Pt 2)

    Topics: Animals; Carbachol; Cholinergic Agonists; Dose-Response Relationship, Drug; Electrophysiology; Enzyme Inhibitors; Female; Glucagon; Hydroxylamine; Indazoles; Insulin; Insulin Secretion; Islets of Langerhans; Mice; Mice, Inbred Strains; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; omega-N-Methylarginine; Potassium

1999
Islet constitutive nitric oxide synthase and glucose regulation of insulin release in mice.
    The Journal of endocrinology, 1999, Volume: 163, Issue:1

    Topics: Analysis of Variance; Animals; Calcium; Culture Techniques; Diazoxide; Enzyme Inhibitors; Female; Glucagon; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Mice; Mice, Inbred Strains; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Potassium Channels

1999
Hyperkinetic circulation and decreased sensitivity to vasoconstrictors following portacaval shunt in the rat. Effects of chronic nitric oxide inhibition.
    Journal of hepatology, 1999, Volume: 31, Issue:4

    Topics: Animals; Blood Circulation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glucagon; Hemodynamics; Male; Methoxamine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Portacaval Shunt, Surgical; Postoperative Period; Rats; Rats, Sprague-Dawley; Splanchnic Circulation; Stereoisomerism; Time Factors; Vasoconstrictor Agents

1999
The role of nitric oxide in mediating pancreatic endocrine responses to insulin-induced hypoglycaemia in the conscious calf.
    Experimental physiology, 1999, Volume: 84, Issue:6

    Topics: Animals; Blood Glucose; Blood Pressure; Cattle; Glucagon; Heart Rate; Hypoglycemia; Insulin; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Pancreas; Pancreatic Polypeptide

1999
Nitric oxide and hydroperoxide affect islet hormone release and Ca(2+) efflux.
    Endocrine, 1999, Volume: 11, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Animals; ATP-Binding Cassette Transporters; Calcium; Catalase; Cyclic AMP; Enzyme Inhibitors; Free Radicals; Glucagon; Glucose; Glutathione Peroxidase; Hydrogen Peroxide; Insulin; Insulin Secretion; Islets of Langerhans; KATP Channels; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Oxidants; Potassium Channels; Potassium Channels, Inwardly Rectifying

1999
Chronic blockade of NO synthase paradoxically increases islet NO production and modulates islet hormone release.
    American journal of physiology. Endocrinology and metabolism, 2000, Volume: 279, Issue:1

    Topics: Animals; Blood Glucose; Calcium; Calmodulin; Carbon Monoxide; Cerebellum; Enzyme Inhibitors; Fasting; Female; Glucagon; Glucose; Indazoles; Insulin; Insulin Secretion; Islets of Langerhans; Mice; Mice, Inbred Strains; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nucleotides, Cyclic; Reference Values; Time Factors

2000
Evaluation of islet heme oxygenase-CO and nitric oxide synthase-NO pathways during acute endotoxemia.
    American journal of physiology. Cell physiology, 2001, Volume: 280, Issue:5

    Topics: Animals; Blood Glucose; Carbon Monoxide; Colforsin; Cyclic AMP; Cyclic GMP; Endotoxemia; Female; Glucagon; Glucose; Heme Oxygenase (Decyclizing); In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Lipopolysaccharides; Mice; Mice, Inbred Strains; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Salmonella typhimurium; Time Factors

2001
Involvement of cyclic guanosine 3',5'-monophosphate in nitric oxide-induced glucagon secretion from pancreatic alpha cells.
    Metabolism: clinical and experimental, 2001, Volume: 50, Issue:6

    Topics: Animals; Arginine; Cell Line; Cyclic GMP; Glucagon; Islets of Langerhans; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Triazenes

2001
Adaptive vasodilatory response after octreotide treatment.
    American journal of physiology. Gastrointestinal and liver physiology, 2001, Volume: 281, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aorta; Blotting, Western; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glucagon; Hypertension, Portal; Indomethacin; Liver Cirrhosis; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrites; Octreotide; Rats; Rats, Sprague-Dawley; Somatostatin; Splanchnic Circulation; Vasoconstrictor Agents; Vasodilation

2001
Insulin and heregulin-beta1 upregulate guanylyl cyclase C expression in rat hepatocytes: reversal by phosphodiesterase-3 inhibition.
    Cellular signalling, 2001, Volume: 13, Issue:9

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Cells, Cultured; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 3; Dexamethasone; Drug Antagonism; Drug Synergism; Enzyme Inhibitors; Glucagon; Guanylate Cyclase; Hepatocytes; Insulin; Male; Neuregulin-1; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Phosphatidylinositol 3-Kinases; Rats; Rats, Sprague-Dawley; Receptors, Enterotoxin; Receptors, Guanylate Cyclase-Coupled; Receptors, Peptide; Up-Regulation

2001
Vasorelaxant effect of glucagon-like peptide-(7-36)amide and amylin on the pulmonary circulation of the rat.
    Regulatory peptides, 2001, Dec-15, Volume: 102, Issue:2-3

    Topics: Acetylcholine; Amyloid; Animals; Anti-Ulcer Agents; Calcitonin Gene-Related Peptide; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; In Vitro Techniques; Islet Amyloid Polypeptide; Male; Neurotransmitter Agents; NG-Nitroarginine Methyl Ester; Norepinephrine; Peptide Fragments; Perfusion; Pulmonary Artery; Pulmonary Circulation; Pulmonary Ventilation; Rats; Rats, Sprague-Dawley; Trachea; Vasoactive Intestinal Peptide; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents

2001
Insulin feedback actions: complex effects involving isoforms of islet nitric oxide synthase.
    Regulatory peptides, 2004, Oct-15, Volume: 122, Issue:2

    Topics: Androstadienes; Animals; C-Peptide; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Feedback, Physiological; Female; Gene Expression Regulation; Glucagon; Glucagon-Like Peptide 1; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Isoenzymes; Mice; Microscopy, Confocal; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peptide Fragments; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Precursors; Wortmannin

2004
Glucose stimulates the expression and activities of nitric oxide synthases in incubated rat islets: an effect counteracted by GLP-1 through the cyclic AMP/PKA pathway.
    Cell and tissue research, 2005, Volume: 319, Issue:2

    Topics: Animals; Bucladesine; Cyclic AMP; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Cyclic N-Oxides; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Free Radical Scavengers; Glucagon; Glucagon-Like Peptide 1; Glucose; Imidazoles; Insulin; Insulin Secretion; Islets of Langerhans; Isoquinolines; Male; Microdissection; Microscopy, Confocal; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peptide Fragments; Protein Kinase Inhibitors; Protein Precursors; Rats; Rats, Sprague-Dawley; Sulfonamides

2005
Ghrelin activates neuronal constitutive nitric oxide synthase in pancreatic islet cells while inhibiting insulin release and stimulating glucagon release.
    Regulatory peptides, 2005, May-15, Volume: 128, Issue:1

    Topics: Animals; Enzyme Activation; Enzyme Inhibitors; Female; Ghrelin; Glucagon; Insulin; Insulin Secretion; Islets of Langerhans; Nerve Tissue Proteins; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Peptide Hormones; Rats; Rats, Sprague-Dawley

2005
Excessive islet NO generation in type 2 diabetic GK rats coincides with abnormal hormone secretion and is counteracted by GLP-1.
    PloS one, 2008, May-14, Volume: 3, Issue:5

    Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Glucagon; Glucagon-Like Peptide 1; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Male; Microscopy, Confocal; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley; Rats, Wistar

2008
Glucagon: The Name Says It All, or Not!
    Endocrinology, 2019, 05-01, Volume: 160, Issue:5

    Topics: Amino Acid Transport Systems; Glucagon; Glucagon-Secreting Cells; Humans; NG-Nitroarginine Methyl Ester; Receptors, Glucagon

2019