Page last updated: 2024-09-04

glucagon and morphine

glucagon has been researched along with morphine in 31 studies

Compound Research Comparison

Studies
(glucagon)
Trials
(glucagon)
Recent Studies (post-2010)
(glucagon)
Studies
(morphine)
Trials
(morphine)
Recent Studies (post-2010) (morphine)
26,0391,4983,05444,2705,2008,695

Protein Interaction Comparison

ProteinTaxonomyglucagon (IC50)morphine (IC50)
Delta-type opioid receptorMus musculus (house mouse)0.2939
Delta-type opioid receptorRattus norvegicus (Norway rat)0.2278
Kappa-type opioid receptorMus musculus (house mouse)0.0828
Mu-type opioid receptorRattus norvegicus (Norway rat)0.0385
Kappa-type opioid receptorRattus norvegicus (Norway rat)0.0545
Mu-type opioid receptorHomo sapiens (human)0.122
Delta-type opioid receptorHomo sapiens (human)0.1199
Kappa-type opioid receptorCavia porcellus (domestic guinea pig)0.9308
Kappa-type opioid receptorHomo sapiens (human)0.655
Mu-type opioid receptorMus musculus (house mouse)0.3305
Mu-type opioid receptorCavia porcellus (domestic guinea pig)0.202
Beta-2 adrenergic receptorCavia porcellus (domestic guinea pig)0.25

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-199022 (70.97)18.7374
1990's6 (19.35)18.2507
2000's3 (9.68)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gourley, DR1
Dobbs, R; Ipp, E; Unger, RH1
Benoit, R; Brazeau, P; Guillemin, R; Harris, D; Lavielle, S; Ling, N; Unger, R; Wasada, T1
Basilico, L; Bonomo, L; Lupini, A; Renda, F1
Fuchs, HF; Maeder, HU1
Chowdhury, AR; Lorber, SH1
Burhol, PG; Jensen, T; Johansen, O; Jorde, R; Reikerås, O; Tønnesen, T2
Brase, DA; Dewey, WL; Tripathi, HL; Ward, CR1
Klaff, LJ; Taborsky, GJ1
Cai, RZ; Karashima, T; Schally, AV1
Amir, S; Holaday, JW; Malcolm, DS1
Asoh, T; Shirasaka, C; Tsuji, H; Uchida, I1
Chernow, B; Holaday, J; Malcolm, D; Zaloga, G1
Hadházy, P1
De Wulf, H; Hers, HG; Hue, L; Stalmans, W1
Parker, CW1
Azimi, F; Dalinka, MK; Gohel, VK; Mandell, GA1
Foley, RE1
Gold, M; Issekutz, B; Miller, HI; Spitzer, JJ1
Baldini, U; Gattoni, F; Mazzoni, R; Raiteri, R; Spagnoli, I; Uslenghi, C1
Abumrad, NN; Cherrington, AD; Lacy, DB; Lacy, WW; McRae, JR; Radosevich, PM; Steiner, KE; Williams, PE1
Ishihara, H; Kudo, M; Matsuki, A; Narita, M; Oyama, T; Yao, M1
Ensinck, JW; Fujimoto, WY; Kanter, RA1
Harris, V; Ipp, E; Schusdziarra, V; Unger, RH1
Burhol, PG; Johansen, O; Reikerås, O; Tønnesen, T1
Burhol, PG; Johansen, O; Jorde, R; Reikerås, O; Tveita, T; Tønnesen, T1
Shirouzu, K; Shirouzu, Y; Yoshida, S1
Boden, GH; Fisher, RS; Gonlachanvit, S; Hsu, CW; Knight, LC; Maurer, AH; Parkman, HP1
Dillon, PF; Lieder, CM; Root-Bernstein, RS1
Ho, MC; Jaw, FS; Lee, PH; Liang, PC; Mo, YH; Peng, SS1

Reviews

4 review(s) available for glucagon and morphine

ArticleYear
Isolation and characterization of membrane drug receptors.
    Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques, 1976, Volume: 20

    Topics: Animals; Drug Tolerance; gamma-Aminobutyric Acid; Glucagon; Glycine; Humans; Insulin; Insulin Resistance; Membranes; Morphine; Receptor, Insulin; Receptors, Adrenergic, beta; Receptors, Cell Surface; Receptors, Cholinergic; Receptors, Drug; Receptors, Opioid; Sodium; Substance-Related Disorders; Toxins, Biological

1976
Radioimmunoassays.
    Progress in clinical pathology, 1972, Volume: 4, Issue:0

    Topics: Adrenocorticotropic Hormone; Animals; Antibodies; Antibody Formation; Bradykinin; Calcitonin; Carcinoembryonic Antigen; Complement System Proteins; Cross Reactions; Cyclic AMP; Digitalis Glycosides; Gastrins; Glucagon; Growth Hormone; Haptens; Hepatitis B Antigens; Humans; Immunization; Insulin; Iodine Radioisotopes; Methods; Morphine; Pituitary Hormones, Posterior; Radioimmunoassay; Thyroid Hormones

1972
Pharmacoradiology of the gastrointestinal tract.
    CRC critical reviews in clinical radiology and nuclear medicine, 1974, Volume: 5, Issue:1

    Topics: Cholecystokinin; Dextrans; Diatrizoate; Gastrointestinal Diseases; Glucagon; Humans; Insulin; Lactose; Methacholine Compounds; Metoclopramide; Morphine; Neostigmine; Propantheline; Radiography; Sorbitol; Tannins

1974
The management of acute pulmonary edema.
    The Medical clinics of North America, 1969, Volume: 53, Issue:2

    Topics: Acute Disease; Cardiac Glycosides; Diuretics; Emergencies; Glucagon; Heart Failure; Humans; Morphine; Oxygen Inhalation Therapy; Posture; Pulmonary Edema

1969

Trials

1 trial(s) available for glucagon and morphine

ArticleYear
Effect of altering gastric emptying on postprandial plasma glucose concentrations following a physiologic meal in type-II diabetic patients.
    Digestive diseases and sciences, 2003, Volume: 48, Issue:3

    Topics: Adult; Aged; Analgesics, Opioid; Anti-Bacterial Agents; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 2; Double-Blind Method; Erythromycin; Female; Gastric Emptying; Gastrointestinal Agents; Glucagon; Humans; Hypoglycemic Agents; Insulin; Male; Middle Aged; Morphine; Placebo Effect; Postprandial Period; Radionuclide Imaging; Stomach

2003

Other Studies

26 other study(ies) available for glucagon and morphine

ArticleYear
Morphine and beta-endorphin influence the secretion of the endocrine pancreas.
    Nature, 1978, Nov-09, Volume: 276, Issue:5684

    Topics: Animals; Dogs; Endorphins; Glucagon; Growth Hormone-Releasing Hormone; Insulin; Insulin Secretion; Islets of Langerhans; Morphine; Naloxone; Receptors, Opioid; Secretory Rate; Time Factors

1978
Synthesis and biological activity of glycosylated analogs of somatostatin.
    Biochemical and biophysical research communications, 1979, Nov-28, Volume: 91, Issue:2

    Topics: Amino Acids; Animals; Diabetes Mellitus, Experimental; Glucagon; Growth Hormone; Insulin; Male; Morphine; Pituitary Gland, Anterior; Rats; Somatostatin; Structure-Activity Relationship

1979
[The employment of pharmacodynamic tests in the radiological examination of the digestive tract (author's transl)].
    La Radiologia medica, 1978, Volume: 64, Issue:12

    Topics: Colon; Digestive System; Duodenum; Esophagus; Gastrointestinal Diseases; Gastrointestinal Motility; Glucagon; Humans; Intestine, Small; Metoclopramide; Morphine; Peristalsis; Propantheline; Radiography; Stomach

1978
[Pharmacoradiography of the gastro intestinal tract (author's transl)].
    Der Radiologe, 1976, Volume: 16, Issue:12

    Topics: Atropine; Butylscopolammonium Bromide; Gastrointestinal Diseases; Gastrointestinal Motility; Glucagon; Humans; Metoclopramide; Morphine; Oxyphenonium; Parasympatholytics; Physostigmine; Propantheline; Radiography

1976
Effects of glucagon and secretin on food- or morphine-induced motor activity of the distal colon, rectum, and anal sphincter.
    The American journal of digestive diseases, 1977, Volume: 22, Issue:9

    Topics: Adult; Aged; Anal Canal; Colon; Female; Food; Gastrointestinal Motility; Glucagon; Humans; Hyperglycemia; Intestine, Large; Male; Middle Aged; Morphine; Muscles; Rectum; Secretin

1977
Increments in glucose, glucagon and insulin after morphine in rats, and naloxone blocking of this effect.
    Life sciences, 1992, Volume: 51, Issue:15

    Topics: Animals; Blood Glucose; Glucagon; Insulin; Morphine; Naloxone; Rats; Time Factors

1992
An insulin-independent mechanism of intrathecal morphine-induced hypoglycemia in mice: mediation through a central alpha-2 adrenergic pathway.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 257, Issue:2

    Topics: Adrenergic alpha-Antagonists; Animals; Blood Glucose; Body Temperature; Drug Interactions; Glucagon; Hypoglycemia; Injections, Spinal; Insulin; Male; Mice; Mice, Inbred ICR; Morphine; Receptors, Adrenergic, alpha; Yohimbine

1991
Role of pancreatic somatostatin in determining glucagon response to arginine and morphine.
    The American journal of physiology, 1987, Volume: 252, Issue:6 Pt 1

    Topics: Animals; Arginine; Dogs; Glucagon; Insulin; Morphine; Pancreas; Somatostatin

1987
Effects of highly potent octapeptide analogs of somatostatin on growth hormone, insulin and glucagon release.
    Life sciences, 1987, Aug-24, Volume: 41, Issue:8

    Topics: Animals; Chlorpromazine; Depression, Chemical; Glucagon; Growth Hormone; Insulin; Insulin Secretion; Islets of Langerhans; Male; Morphine; Octreotide; Phenobarbital; Pituitary Gland, Anterior; Rats; Secretory Rate; Somatostatin

1987
Central glucagon antagonizes morphine- and stress-induced antinociception in the mouse.
    NIDA research monograph, 1986, Volume: 75

    Topics: Analgesia; Animals; Cerebral Ventricles; Glucagon; Male; Mice; Mice, Inbred ICR; Morphine; Pain; Restraint, Physical; Stress, Psychological

1986
Effects of epidural administration of local anaesthetics or morphine on postoperative nitrogen loss and catabolic hormones.
    The British journal of surgery, 1987, Volume: 74, Issue:5

    Topics: Anesthetics, Local; Epinephrine; Female; Glucagon; Humans; Hydrocortisone; Injections, Epidural; Intraoperative Care; Male; Middle Aged; Morphine; Nitrogen; Norepinephrine; Postoperative Period

1987
Glucagon is an antagonist of morphine bradycardia and antinociception.
    Life sciences, 1986, Aug-04, Volume: 39, Issue:5

    Topics: Analgesia; Animals; Biguanides; Glucagon; Heart Rate; Kinetics; Male; Morphine; Rats; Rats, Inbred Strains

1986
Actions of glucagon and dibutyryl cyclic 3',5'-AMP on chronotropic responses to vagal stimulation and acetylcholine.
    Pharmacology, 1973, Volume: 9, Issue:5

    Topics: Acetylcholine; Animals; Cyclic AMP; Depression, Chemical; Electric Stimulation; Ganglia; Glucagon; Guinea Pigs; Heart Atria; Heart Rate; Hexamethonium Compounds; In Vitro Techniques; Morphine; Nerve Endings; Physostigmine; Synaptic Transmission; Time Factors; Vagus Nerve

1973
The sequential inactivation of glycogen phosphorylase and activation of glycogen synthetase in liver after the administration of glucose to mice and rats. The mechanism of the hepatic threshold to glucose.
    European journal of biochemistry, 1974, Jan-03, Volume: 41, Issue:1

    Topics: Animals; Enzyme Activation; Freezing; Glucagon; Glucose; Glycogen Synthase; Insulin; Liver; Male; Mice; Morphine; Pentobarbital; Phosphoric Monoester Hydrolases; Phosphorylases; Rats; Time Factors

1974
Effect of exercise and lactic acid infusion on individual free fatty acids of plasma.
    The American journal of physiology, 1963, Volume: 205, Issue:5

    Topics: Animals; Chloralose; Dogs; Epinephrine; Fatty Acids; Fatty Acids, Nonesterified; Female; Glucagon; Insulin; Lactates; Linoleic Acids; Male; Morphine; Norepinephrine; Oleic Acids; Oxygen Consumption; Palmitic Acids; Pentobarbital; Physical Exertion; Stearic Acids

1963
[Pharmaco-radiodiagnosis of the digestive tract].
    Minerva medica, 1983, Jun-30, Volume: 74, Issue:27

    Topics: Depression, Chemical; Digestive System; Endoscopy; Glucagon; Humans; Metoclopramide; Morphine; Parasympatholytics; Peristalsis; Radiography; Somatostatin; Stimulation, Chemical

1983
Effects of morphine on glucose homeostasis in the conscious dog.
    The Journal of clinical investigation, 1984, Volume: 74, Issue:4

    Topics: Animals; Blood Glucose; Dogs; Dose-Response Relationship, Drug; Female; Glucagon; Glucose; Homeostasis; Hyperglycemia; Insulin; Kinetics; Ligation; Male; Morphine; Somatostatin

1984
[Endocrine function following epidural morphine in man. VI. Effects on glucose metabolism].
    Masui. The Japanese journal of anesthesiology, 1984, Volume: 33, Issue:11

    Topics: Adult; Anesthesia, Epidural; Anesthesia, General; Blood Glucose; Catecholamines; Female; Glucagon; Halothane; Humans; Middle Aged; Morphine; Nitrous Oxide

1984
Disparate effects of enkephalin and morphine upon insulin and glucagon secretion by islet cell cultures.
    Diabetes, 1980, Volume: 29, Issue:1

    Topics: Animals; Animals, Newborn; Cells, Cultured; Depression, Chemical; Endorphins; Enkephalins; Glucagon; Insulin; Insulin Secretion; Islets of Langerhans; Morphine; Naloxone; Rats

1980
Morphine-induced hyperglycemia: role of insulin and glucagon.
    Endocrinology, 1980, Volume: 107, Issue:2

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dogs; Glucagon; Hyperglycemia; Insulin; Morphine

1980
Morphine effects on the release of glucagon, insulin and somatostatin from the isolated, perfused rat pancreas.
    Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1994, Volume: 194, Issue:4

    Topics: Animals; Dose-Response Relationship, Drug; Glucagon; Insulin; Male; Morphine; Pancreas; Perfusion; Rats; Rats, Wistar; Somatostatin

1994
Comparison of the modifying effects of somatostatin and propranolol on morphine-induced changes in glucose, glucagon and insulin levels in fed rats.
    Life sciences, 1993, Volume: 52, Issue:2

    Topics: Animals; Blood Glucose; Drug Synergism; Food; Glucagon; Insulin; Morphine; Propranolol; Rats; Rats, Wistar; Somatostatin

1993
Morphine and morphine/naloxone modification of glucose, glucagon and insulin levels in fasted and fed rats.
    Scandinavian journal of clinical and laboratory investigation, 1993, Volume: 53, Issue:8

    Topics: Animals; Blood Glucose; Fasting; Glucagon; Insulin; Morphine; Naloxone; Rats; Rats, Wistar

1993
Effect of fentanyl on morphine levels in the brain in rats receiving intracerebroventricular injection of TNF-alpha.
    The American journal of physiology, 1998, Volume: 275, Issue:4

    Topics: Animals; Blood Glucose; Blood Proteins; Brain; Cerebral Ventricles; Corticosterone; Epinephrine; Fentanyl; Glucagon; Glucose; Hormones; Hydrocortisone; Injections, Intraventricular; Insulin; Leucine; Male; Morphine; Muscle Proteins; Muscle, Skeletal; Norepinephrine; Rats; Rats, Sprague-Dawley; Tissue Distribution; Tumor Necrosis Factor-alpha

1998
Molecular shielding of electric field complex dissociation.
    Biophysical journal, 2006, Feb-15, Volume: 90, Issue:4

    Topics: Animals; Cattle; Electromagnetic Fields; Epinephrine; Glucagon; Insulin; Membrane Potentials; Models, Biological; Morphine; Norepinephrine; Protein Binding; Serum Albumin, Bovine

2006
Morphine- and glucagon-augmented magnetic resonance cholangiopancreatography to evaluate living liver donors.
    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2009, Volume: 15, Issue:9

    Topics: Adolescent; Adult; Cholangiopancreatography, Magnetic Resonance; Common Bile Duct; Female; Glucagon; Hepatectomy; Hepatic Duct, Common; Humans; Image Enhancement; Injections, Intramuscular; Injections, Intravenous; Liver Transplantation; Living Donors; Male; Middle Aged; Morphine; Pancreatic Ducts; Predictive Value of Tests; Preoperative Care; Young Adult

2009