Page last updated: 2024-09-04

glucagon and methotrexate

glucagon has been researched along with methotrexate in 6 studies

Compound Research Comparison

Studies
(glucagon)
Trials
(glucagon)
Recent Studies (post-2010)
(glucagon)
Studies
(methotrexate)
Trials
(methotrexate)
Recent Studies (post-2010) (methotrexate)
26,0391,4983,05441,5935,66611,969

Protein Interaction Comparison

ProteinTaxonomyglucagon (IC50)methotrexate (IC50)
Thymidylate synthase Escherichia coli1.8
nuclear receptor coactivator 3 isoform aHomo sapiens (human)0.211
Toll-like receptor 4Homo sapiens (human)1.04
Fatty-acid amide hydrolase 1Mus musculus (house mouse)0.08
Dihydrofolate reductaseHomo sapiens (human)0.0522
Dihydrofolate reductaseMus musculus (house mouse)0.0331
Dihydrofolate reductase Bos taurus (cattle)0.0348
Dihydrofolate reductaseGallus gallus (chicken)0.0545
Dihydrofolate reductaseEnterococcus faecium0.0014
Dihydrofolate reductaseLacticaseibacillus casei0.0138
Thymidylate synthaseHomo sapiens (human)0.343
5-hydroxytryptamine receptor 2CRattus norvegicus (Norway rat)0.0147
Thymidylate synthaseEscherichia coli K-120.0181
Dihydrofolate reductaseEscherichia coli K-120.1529
Bifunctional dihydrofolate reductase-thymidylate synthasePlasmodium falciparum K10.084
Folate receptor betaHomo sapiens (human)0.1585
5-hydroxytryptamine receptor 2ARattus norvegicus (Norway rat)0.0011
Cytochrome P450 11B1, mitochondrial Bos taurus (cattle)0.0012
Folate receptor alphaHomo sapiens (human)0.2263
Dihydrofolate reductasePneumocystis carinii0.0717
Histidine decarboxylaseRattus norvegicus (Norway rat)0.0014
Trifunctional purine biosynthetic protein adenosine-3Homo sapiens (human)0.01
Bifunctional purine biosynthesis protein ATICHomo sapiens (human)0.01
Delta-type opioid receptorRattus norvegicus (Norway rat)0.003
Mu-type opioid receptorRattus norvegicus (Norway rat)0.003
Kappa-type opioid receptorRattus norvegicus (Norway rat)0.003
Reduced folate transporterHomo sapiens (human)0.012
Dihydrofolate reductaseMycobacterium tuberculosis H37Rv0.0174
Folylpolyglutamate synthase, mitochondrialHomo sapiens (human)3.2
Bifunctional dihydrofolate reductase-thymidylate synthaseToxoplasma gondii0.0547
Bifunctional dihydrofolate reductase-thymidylate synthaseTrypanosoma cruzi0.11
Dihydrofolate reductase Bacillus anthracis0.0136
Dihydrofolate reductaseRattus norvegicus (Norway rat)0.0047
Proton-coupled folate transporterHomo sapiens (human)0.1207

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19903 (50.00)18.7374
1990's2 (33.33)18.2507
2000's0 (0.00)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Belousova, AK1
Lin, MS; Winchell, HS1
Bracht, A; Ishii-Iwamoto, EL; Nascimento, EA; Yamamoto, NS1
Abad, LW; Dinarello, CA; Dolnikowski, G; Hartman, WJ; Lundgren, N; Rall, LC; Rosen, CJ; Roubenoff, R1
KEIDAN, SE1
Eaton, P; Rudyk, O1

Reviews

1 review(s) available for glucagon and methotrexate

ArticleYear
[Molecular basis of the relation between the cytotoxic effect of antineoplastic compounds and the cell cycle phase].
    Voprosy onkologii, 1972, Volume: 18, Issue:8

    Topics: Adenocarcinoma; Adrenocorticotropic Hormone; Alkylating Agents; Androgens; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Culture Techniques; Cyclic AMP; Dactinomycin; DNA Replication; DNA, Neoplasm; Estrogens; Fluorouracil; Glucagon; Glucocorticoids; Mathematics; Methotrexate; Mitosis; Molecular Biology; Neoplasm Transplantation; Neoplasms, Experimental; Receptors, Drug; RNA, Neoplasm; Sarcoma, Experimental

1972

Other Studies

5 other study(ies) available for glucagon and methotrexate

ArticleYear
Kinetics of amino acid transport across bone marrow cell membranes.
    The Journal of clinical investigation, 1970, Volume: 49, Issue:4

    Topics: Amino Acids; Animals; Biological Transport, Active; Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Cell Membrane; DNA; Dogs; Extracellular Space; Glucagon; Glutamates; Histidine; Imidazoles; Insulin; Kinetics; Methionine; Methotrexate; Models, Biological; Serine; Time Factors; Tryptophan

1970
Naproxen inhibits hepatic glycogenolysis induced by Ca(2+)-dependent agents.
    General pharmacology, 1995, Volume: 26, Issue:1

    Topics: Animals; Calcium; Glucagon; Liver; Liver Glycogen; Male; Methotrexate; Naproxen; Phenylephrine; Rats; Rats, Wistar

1995
Protein metabolism in rheumatoid arthritis and aging. Effects of muscle strength training and tumor necrosis factor alpha.
    Arthritis and rheumatism, 1996, Volume: 39, Issue:7

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antirheumatic Agents; Arthritis, Rheumatoid; Exercise; Female; Glucagon; Growth Hormone; Humans; Leucine; Male; Methotrexate; Middle Aged; Proteins; Time Factors; Tumor Necrosis Factor-alpha

1996
PROLONGED REMISSION IN ACUTE LEUKAEMIA.
    British medical journal, 1964, Dec-05, Volume: 2, Issue:5422

    Topics: Blood Transfusion; Bone Marrow Cells; Bone Marrow Examination; Child; Diabetes Mellitus; Glucagon; Humans; Leukemia; Mercaptopurine; Methotrexate; Prednisolone; Prognosis; Toxicology; Triamcinolone

1964
Examining a role for PKG Iα oxidation in the pathogenesis of cardiovascular dysfunction during diet-induced obesity.
    Free radical biology & medicine, 2017, Volume: 110

    Topics: Animals; Aorta; Carmustine; Cattle; Cyclic GMP-Dependent Protein Kinase Type I; Diet, High-Fat; Endothelial Cells; Gene Expression Regulation; Glucagon; Hypertension; Leptin; Methotrexate; Mice; Myocytes, Smooth Muscle; Nitric Oxide Synthase Type III; Obesity; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Resistin; Signal Transduction; Sugar Acids; Uncoupling Agents

2017