Page last updated: 2024-09-04

glucagon and linagliptin

glucagon has been researched along with linagliptin in 5 studies

Compound Research Comparison

Studies
(glucagon)
Trials
(glucagon)
Recent Studies (post-2010)
(glucagon)
Studies
(linagliptin)
Trials
(linagliptin)
Recent Studies (post-2010) (linagliptin)
26,0391,4983,054598149554

Protein Interaction Comparison

ProteinTaxonomyglucagon (IC50)linagliptin (IC50)
Cytochrome P450 1A2Homo sapiens (human)0.3
Muscarinic acetylcholine receptor M1Homo sapiens (human)0.2967
Dipeptidyl peptidase 4Homo sapiens (human)0.0008
Prolyl endopeptidase FAPMus musculus (house mouse)0.37
Prolyl endopeptidase FAPHomo sapiens (human)0.0799

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Anastassiadis, E; Diessel, S; Forst, T; Löffler, A; Pfützner, A1
Aguilar, R; Hehnke, U; Lajara, R; von Eynatten, M; Woerle, HJ1
Ahrén, B; Eto, T; Irie, S; Kurose, T; Kuwata, H; Murotani, K; Seino, S; Seino, Y; Shiramoto, M; Yabe, D1
Andersen, G; Falk, A; Fischer, A; Forst, T; Heise, T; Kapitza, C; Plum-Mörschel, L; Voswinkel, S; Weber, MM1
Dong, EW; Fonseca, VA; Htun, W; Mauvais-Jarvis, F; Wu, H; Wu, M; Zhang, Y1

Trials

3 trial(s) available for glucagon and linagliptin

ArticleYear
Effect of linagliptin compared with glimepiride on postprandial glucose metabolism, islet cell function and vascular function parameters in patients with type 2 diabetes mellitus receiving ongoing metformin treatment.
    Diabetes/metabolism research and reviews, 2014, Volume: 30, Issue:7

    Topics: Aged; Biomarkers; Blood Glucose; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Glucagon; Glucagon-Like Peptide 1; Humans; Hypoglycemic Agents; Insulin; Islets of Langerhans; Linagliptin; Male; Metformin; Middle Aged; Plasminogen Activator Inhibitor 1; Postprandial Period; Proinsulin; Purines; Quinazolines; Risk Factors; Sulfonylurea Compounds

2014
Effects of DPP-4 inhibitor linagliptin and GLP-1 receptor agonist liraglutide on physiological response to hypoglycaemia in Japanese subjects with type 2 diabetes: A randomized, open-label, 2-arm parallel comparative, exploratory trial.
    Diabetes, obesity & metabolism, 2017, Volume: 19, Issue:3

    Topics: Aged; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Epinephrine; Female; Glucagon; Glucagon-Like Peptide-1 Receptor; Glucose Clamp Technique; Human Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Hypoglycemic Agents; Japan; Linagliptin; Liraglutide; Male; Middle Aged; Norepinephrine

2017
Effects on α- and β-cell function of sequentially adding empagliflozin and linagliptin to therapy in people with type 2 diabetes previously receiving metformin: An exploratory mechanistic study.
    Diabetes, obesity & metabolism, 2017, Volume: 19, Issue:4

    Topics: Aged; Benzhydryl Compounds; Blood Glucose; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glucagon; Glucagon-Secreting Cells; Glucose Clamp Technique; Glucosides; Humans; Hypoglycemic Agents; Insulin; Insulin-Secreting Cells; Linagliptin; Male; Middle Aged; Postprandial Period; Proinsulin; Treatment Outcome

2017

Other Studies

2 other study(ies) available for glucagon and linagliptin

ArticleYear
Efficacy and safety of linagliptin in subjects with long-standing type 2 diabetes mellitus (>10 years): evidence from pooled data of randomized, double-blind, placebo-controlled, phase III trials.
    Clinical therapeutics, 2014, Nov-01, Volume: 36, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Blood Glucose; Clinical Trials, Phase III as Topic; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Drug Therapy, Combination; Female; Glucagon; Glycated Hemoglobin; Humans; Hypoglycemia; Hypoglycemic Agents; Linagliptin; Male; Middle Aged; Randomized Controlled Trials as Topic; Retrospective Studies; Sulfonylurea Compounds; Treatment Outcome

2014
Differential Effects of Linagliptin on the Function of Human Islets Isolated from Non-diabetic and Diabetic Donors.
    Scientific reports, 2017, 08-11, Volume: 7, Issue:1

    Topics: Cells, Cultured; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Secreting Cells; Humans; Hypoglycemic Agents; Insulin Secretion; Insulin-Secreting Cells; Linagliptin

2017