Page last updated: 2024-09-04

glucagon and inositol 1,4,5-trisphosphate

glucagon has been researched along with inositol 1,4,5-trisphosphate in 21 studies

Compound Research Comparison

Studies
(glucagon)
Trials
(glucagon)
Recent Studies (post-2010)
(glucagon)
Studies
(inositol 1,4,5-trisphosphate)
Trials
(inositol 1,4,5-trisphosphate)
Recent Studies (post-2010) (inositol 1,4,5-trisphosphate)
26,0391,4983,0546,6001589

Protein Interaction Comparison

ProteinTaxonomyglucagon (IC50)inositol 1,4,5-trisphosphate (IC50)
Inositol-trisphosphate 3-kinase ARattus norvegicus (Norway rat)4.45
Inositol 1,4,5-trisphosphate receptor type 2Homo sapiens (human)0.03
Inositol 1,4,5-trisphosphate receptor type 3Homo sapiens (human)0.03
Inositol 1,4,5-trisphosphate receptor type 1Homo sapiens (human)0.03

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19906 (28.57)18.7374
1990's13 (61.90)18.2507
2000's1 (4.76)29.6817
2010's0 (0.00)24.3611
2020's1 (4.76)2.80

Authors

AuthorsStudies
Ishac, EJ; Kunos, G; Lazar-Wesley, E1
Blackmore, PF; Exton, JH1
Claret, M; Hilly, M; Mauger, JP; Pietri, F1
Ganas, L; Studer, RK1
Blackmore, PF; Bocckino, SB; Charest, R; Exton, JH; Lynch, CJ1
Kimura, S; Kojima, I; Mine, T; Ogata, E1
Blackmore, PF; Charest, R; Exton, JH1
Keppens, S1
Chen, S; Stucki, JW; Ubl, JJ1
Gylfe, E; Lund, PE1
Jungermann, K; Miura, H; Neuschäfer-Rube, F; Püschel, GP1
Janssens, PA; Kleineke, JW1
Jungermann, K; Kirchner, C; Püschel, GP; Schröder, A1
Ammon, HP; Verspohl, EJ; Wahl, MA1
Aerts, R; De Wulf, H; Keppens, S; Moshage, H; Vandekerckhove, A; Yap, SH1
Kajiyama, Y; Sanai, Y; Ui, M1
Grapengiesser, E; Gylfe, E; Hellman, B; Liu, YJ1
Chaudry, IH; Mahmoud, MS; Wang, P1
Bali, JP; Bataille, D; Geneviève, R; Jarrousse, C; Le Nguyen, D; Magous, R; Martinez, J; Mochizuki, T; Rodier, G1
Chen, TH; Cheng, H; Hsu, WH; Yibchok-Anun, S1
Bartlett, PJ; Brumer, RP; Corrêa-Velloso, JC; Sandiford, OA; Thomas, AP; Thomas, SJ1

Other Studies

21 other study(ies) available for glucagon and inositol 1,4,5-trisphosphate

ArticleYear
Rapid inverse changes in alpha 1B- and beta 2-adrenergic receptors and gene transcripts in acutely isolated rat liver cells.
    Journal of cellular physiology, 1992, Volume: 152, Issue:1

    Topics: Animals; Cells, Cultured; Colforsin; Cyclic AMP; Cycloheximide; Glucagon; Inositol 1,4,5-Trisphosphate; Isoproterenol; Liver; Male; Phenylephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; RNA, Messenger; Time Factors; Transcription, Genetic

1992
Studies on the hepatic calcium-mobilizing activity of aluminum fluoride and glucagon. Modulation by cAMP and phorbol myristate acetate.
    The Journal of biological chemistry, 1986, Aug-25, Volume: 261, Issue:24

    Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Adrenergic alpha-Agonists; Aluminum; Aluminum Compounds; Angiotensin II; Calcium; Colforsin; Cyclic AMP; Drug Synergism; Fluorides; Glucagon; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Liver; Pertussis Toxin; Phorbols; Protein Kinase C; Sodium Fluoride; Tetradecanoylphorbol Acetate; Thionucleotides; Vasopressins; Virulence Factors, Bordetella

1986
Hormonal regulation of inositol 1,4,5-trisphosphate receptor in rat liver.
    The Journal of biological chemistry, 1989, May-25, Volume: 264, Issue:15

    Topics: Animals; Bucladesine; Calcium Channels; Cell Membrane; Cells, Cultured; Female; Glucagon; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Inositol Phosphates; Kinetics; Liver; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Sugar Phosphates; Vasopressins

1989
Effect of diabetes on hormone-stimulated and basal hepatocyte calcium metabolism.
    Endocrinology, 1989, Volume: 125, Issue:5

    Topics: Animals; Arginine Vasopressin; Calcium; Cells, Cultured; Diabetes Mellitus, Experimental; Epinephrine; Glucagon; Inositol 1,4,5-Trisphosphate; Kinetics; Liver; Male; Phentolamine; Phosphorylases; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Reference Values

1989
Inhibition of hepatic alpha 1-adrenergic effects and binding by phorbol myristate acetate.
    The Journal of biological chemistry, 1985, Mar-10, Volume: 260, Issue:5

    Topics: Animals; Calcimycin; Calcium; Cyclic AMP; Dose-Response Relationship, Drug; Epinephrine; Glucagon; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Liver; Phentolamine; Phorbols; Phosphorylase a; Propranolol; Protein Kinase C; Protein Kinases; Rats; Receptors, Adrenergic, alpha; Tetradecanoylphorbol Acetate; Time Factors; Vasopressins

1985
Assessment of the role of Ca2+ mobilization from intracellular pool(s), using dantrolene, in the glycogenolytic action of alpha-adrenergic stimulation in perfused rat liver.
    Biochimica et biophysica acta, 1987, Feb-18, Volume: 927, Issue:2

    Topics: Animals; Biological Transport; Body Fluids; Calcium; Dantrolene; Extracellular Space; Glucagon; Glucose; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Intracellular Fluid; Liver; Liver Glycogen; Male; Phenylephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha

1987
Characterization of responses of isolated rat hepatocytes to ATP and ADP.
    The Journal of biological chemistry, 1985, Dec-15, Volume: 260, Issue:29

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Dose-Response Relationship, Drug; Enzyme Activation; Glucagon; Hydrolysis; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Liver; Male; Phosphorylase a; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Time Factors

1985
Effect of genistein on both basal and glucagon-induced levels of cAMP in rat hepatocytes.
    Biochemical pharmacology, 1995, Oct-12, Volume: 50, Issue:8

    Topics: Animals; Cells, Cultured; Cyclic AMP; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Genistein; Glucagon; Growth Inhibitors; Inositol 1,4,5-Trisphosphate; Isoflavones; Liver; Phosphorylases; Rats

1995
Anti-diabetic biguanides inhibit hormone-induced intracellular Ca2+ concentration oscillations in rat hepatocytes.
    The Biochemical journal, 1994, Dec-01, Volume: 304 ( Pt 2)

    Topics: Animals; Biguanides; Bucladesine; Calcium; Chlorides; Colforsin; Cyclic AMP; Glucagon; Inositol 1,4,5-Trisphosphate; Insulin; Liver; Male; Manganese Compounds; Metformin; Phenformin; Phenylephrine; Rats; Rats, Wistar; Second Messenger Systems

1994
Caffeine inhibits cytoplasmic Ca2+ oscillations induced by carbachol and guanosine 5'-O-(3-thiotriphosphate) in hyperpolarized pancreatic beta-cells.
    Naunyn-Schmiedeberg's archives of pharmacology, 1994, Volume: 349, Issue:5

    Topics: Adenosine Triphosphate; Animals; Caffeine; Calcium; Carbachol; Cells, Cultured; Glucagon; Glucose; Guanosine 5'-O-(3-Thiotriphosphate); Inositol 1,4,5-Trisphosphate; Islets of Langerhans; Mice; Mice, Obese; Potassium Channels

1994
Inhibition by the protein kinase C activator 4 beta-phorbol 12-myristate 13-acetate of the prostaglandin F2 alpha-mediated and noradrenaline-mediated but not glucagon-mediated activation of glycogenolysis in rat liver.
    European journal of biochemistry, 1993, Oct-01, Volume: 217, Issue:1

    Topics: Aluminum Compounds; Animals; Dinoprost; Enzyme Activation; Fluorides; Glucagon; Glucose; Glycogen; Guanosine 5'-O-(3-Thiotriphosphate); Inositol 1,4,5-Trisphosphate; Lactates; Lactic Acid; Liver; Male; Norepinephrine; Phosphorylases; Protein Kinase C; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Type C Phospholipases

1993
Hormone-induced rise in cytosolic Ca2+ in axolotl hepatocytes: extracellular origin and control by cAMP.
    The American journal of physiology, 1993, Volume: 265, Issue:5 Pt 1

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Ambystoma mexicanum; Animals; Calcium; Cells, Cultured; Cyclic AMP; Cytosol; Epinephrine; Glucagon; Guanosine Triphosphate; Inositol 1,4,5-Trisphosphate; Isoproterenol; Kinetics; Liver; Phentolamine; Propranolol; Thionucleotides; Vasotocin

1993
Glycogenolytic and antiglycogenolytic prostaglandin E2 actions in rat hepatocytes are mediated via different signalling pathways.
    European journal of biochemistry, 1993, Dec-15, Volume: 218, Issue:3

    Topics: Animals; Cells, Cultured; Dinoprostone; Glucagon; Glucose; Inositol 1,4,5-Trisphosphate; Liver; Male; Pertussis Toxin; Phosphorylases; Rats; Rats, Wistar; Receptors, Prostaglandin E; Signal Transduction; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella

1993
Activin A: its effects on rat pancreatic islets and the mechanism of action involved.
    Life sciences, 1993, Volume: 53, Issue:13

    Topics: Activins; Analysis of Variance; Animals; Calcium Radioisotopes; Dose-Response Relationship, Drug; Female; Glucagon; In Vitro Techniques; Inhibins; Inositol 1,4,5-Trisphosphate; Insulin; Insulin Secretion; Islets of Langerhans; Male; Potassium; Rats; Rats, Wistar; Rubidium Radioisotopes

1993
Regulation of glycogen phosphorylase activity in isolated human hepatocytes.
    Hepatology (Baltimore, Md.), 1993, Volume: 17, Issue:4

    Topics: Adenosine Triphosphate; Adult; Angiotensin II; Animals; Cells, Cultured; Cyclic AMP; Enzyme Activation; Glucagon; Humans; Inositol 1,4,5-Trisphosphate; Isoproterenol; Kidney Transplantation; Kinetics; Liver; Middle Aged; Phenylephrine; Phosphorylases; Rats; Time Factors; Tissue Donors; Vasopressins

1993
A role of asialoglycoproteins for plasma-membrane-induced inhibition of the switching from alpha 1 to beta subtypes in adrenergic response during primary culture of rat hepatocytes.
    The Biochemical journal, 1996, Jun-15, Volume: 316 ( Pt 3)

    Topics: 1-Methyl-3-isobutylxanthine; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Aging; Animals; Asialoglycoproteins; beta-Galactosidase; Cell Division; Cell Membrane; Cells, Cultured; Cyclic AMP; Glucagon; Glycoside Hydrolases; Inositol 1,4,5-Trisphosphate; Isoproterenol; Kinetics; Liver; Membrane Glycoproteins; Neuraminidase; Phenylephrine; Rats; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, beta

1996
Crosstalk between the cAMP and inositol trisphosphate-signalling pathways in pancreatic beta-cells.
    Archives of biochemistry and biophysics, 1996, Oct-15, Volume: 334, Issue:2

    Topics: Animals; Caffeine; Calcium; Cells, Cultured; Cyclic AMP; Cytosol; Diazoxide; Gallopamil; Glucagon; Glucose; Inositol 1,4,5-Trisphosphate; Islets of Langerhans; Kinetics; Membrane Potentials; Mice; Mice, Obese; Oscillometry; Potassium; Ryanodine; Signal Transduction; Strontium; Tetradecanoylphorbol Acetate

1996
Salutary effects of ATP-MgCl2 on altered hepatocyte signal transduction after hemorrhagic shock.
    The American journal of physiology, 1997, Volume: 272, Issue:6 Pt 1

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine Triphosphate; Analysis of Variance; Animals; Cells, Cultured; Cyclic AMP; Glucagon; Inositol 1,4,5-Trisphosphate; Liver; Male; Rats; Rats, Sprague-Dawley; Receptors, Glucagon; Receptors, Vasopressin; Resuscitation; Shock, Hemorrhagic; Signal Transduction; Vasopressins

1997
Glicentin and oxyntomodulin modulate both the phosphoinositide and cyclic adenosine monophosphate signaling pathways in gastric myocytes.
    Endocrinology, 1999, Volume: 140, Issue:1

    Topics: Animals; Calcium; Carbachol; Colforsin; Cyclic AMP; Glicentin; Glucagon; Glucagon-Like Peptides; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Muscle Contraction; Muscle, Smooth; Oxyntomodulin; Peptide Fragments; Pertussis Toxin; Phosphatidylinositols; Protein Precursors; Pyloric Antrum; Rabbits; Signal Transduction; Type C Phospholipases; Virulence Factors, Bordetella

1999
Mechanisms of AVP-induced glucagon release in clonal alpha-cells in-R1-G9: involvement of Ca(2+)-dependent and -independent pathways.
    British journal of pharmacology, 2000, Volume: 129, Issue:2

    Topics: Amino Acid Chloromethyl Ketones; Animals; Arginine Vasopressin; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Clone Cells; Cricetinae; Cyclic AMP; Enzyme Inhibitors; Estrenes; Glucagon; Inositol 1,4,5-Trisphosphate; Nimodipine; Phosphodiesterase Inhibitors; Pyrrolidinones; Renal Agents; Serine Proteinase Inhibitors; Thapsigargin

2000
Short-term high-fat diet feeding of mice suppresses catecholamine-stimulated Ca
    The Journal of physiology, 2023, Volume: 601, Issue:8

    Topics: Animals; Catecholamines; Diabetes Mellitus, Type 2; Diet, High-Fat; Glucagon; Hepatocytes; Inositol 1,4,5-Trisphosphate; Liver; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Norepinephrine

2023