Page last updated: 2024-09-04

glucagon and h 89

glucagon has been researched along with h 89 in 14 studies

Compound Research Comparison

Studies
(glucagon)
Trials
(glucagon)
Recent Studies (post-2010)
(glucagon)
Studies
(h 89)
Trials
(h 89)
Recent Studies (post-2010) (h 89)
26,0391,4983,0541,6190409

Protein Interaction Comparison

ProteinTaxonomyglucagon (IC50)h 89 (IC50)
Rho-associated protein kinase 2Homo sapiens (human)1.9504
Ribosomal protein S6 kinase alpha-5Homo sapiens (human)0.12
cAMP-dependent protein kinase catalytic subunit alphaBos taurus (cattle)0.073
cAMP-dependent protein kinase catalytic subunit alpha Mus musculus (house mouse)0.381
cAMP-dependent protein kinase catalytic subunit alphaHomo sapiens (human)0.6365
cAMP-dependent protein kinase catalytic subunit gammaHomo sapiens (human)0.6365
cAMP-dependent protein kinase catalytic subunit betaHomo sapiens (human)0.6365
Ribosomal protein S6 kinase beta-1Homo sapiens (human)0.08
RAC-alpha serine/threonine-protein kinaseHomo sapiens (human)1.9886
RAC-beta serine/threonine-protein kinaseHomo sapiens (human)0.5417
Rho-associated protein kinase 2Rattus norvegicus (Norway rat)0.27
RAC-gamma serine/threonine-protein kinaseHomo sapiens (human)0.3207

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (35.71)18.2507
2000's7 (50.00)29.6817
2010's2 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alvaro, D; Bini, A; Capocaccia, L; Della Guardia, P; Furfaro, S; Gigliozzi, A; La Rosa, T; Piat, C1
Kato, M; Ma, HT; Tatemoto, K1
Haneda, T; Kikuchi, K; Osaki, J; Sakai, H1
Fukuzawa, J; Haneda, T; Kashiwagi, Y; Kikuchi, K; Oi, S; Osaki, J; Sakai, H1
Cantore, ML; Castilla, R; Passeron, S1
Doyle, ME; Egan, JM; Wang, X; Zhou, J1
Bhatt, HS; Easom, RA; Lawrence, MC1
Aguilar-Bryan, L; Bryan, J; Crane, A; Hu, M; Nakazaki, M; Seghers, V; Ullrich, S1
Kim, SK; Novak, RF; Woodcroft, KJ1
Briaud, I; Dickson, LM; Lingohr, MK; Rhodes, CJ; Wrede, CE1
Matsui, H; Miura, Y1
Jimenez-Feltstrom, J; Lundquist, I; Salehi, A1
Hernández-Cascales, J; Merino, B; Quesada, I1
Go, Y; Ham, HJ; Harris, RA; He, L; Jeon, JH; Jeon, YH; Jeoung, NH; Kim, BG; Kim, JE; Koo, SH; Kwon, WH; Lee, IK; Park, BY; Park, KG; Yoo, EK1

Other Studies

14 other study(ies) available for glucagon and h 89

ArticleYear
Effect of glucagon on intracellular pH regulation in isolated rat hepatocyte couplets.
    The Journal of clinical investigation, 1995, Volume: 96, Issue:2

    Topics: Animals; Antiporters; Bicarbonates; Bile; Bucladesine; Cells, Cultured; Chloride-Bicarbonate Antiporters; Chlorides; Cholagogues and Choleretics; Colchicine; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Glucagon; Hydrogen-Ion Concentration; Intracellular Fluid; Isoquinolines; Liver; Male; Nitrobenzoates; Rats; Rats, Wistar; Sodium; Sodium-Hydrogen Exchangers; Sulfonamides; Tetradecanoylphorbol Acetate; Thionucleotides

1995
GLP-1 depolarizes the rat pancreatic beta cell in a Na(+)-dependent manner.
    Regulatory peptides, 1996, Apr-09, Volume: 62, Issue:1

    Topics: Animals; Barium; Calcium Channel Blockers; Cell Polarity; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Glucagon; Glucagon-Like Peptide 1; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Isoquinolines; Male; Meglumine; Membrane Potentials; Pancreatic Hormones; Patch-Clamp Techniques; Peptides; Protein Precursors; Rats; Rats, Wistar; Sodium; Sulfonamides

1996
cAMP-mediated c-fos expression in pressure-overloaded acceleration of protein synthesis in adult rat heart.
    Cardiovascular research, 1997, Volume: 33, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Blotting, Northern; Cardiomegaly; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Gene Expression; Genes, fos; Glucagon; Isoquinolines; Male; Perfusion; Phosphodiesterase Inhibitors; Pressure; Protein Biosynthesis; Protein Kinase C; Rats; Rats, Sprague-Dawley; Sulfonamides

1997
Pressure-induced expression of heat shock protein 70 mRNA in adult rat heart is coupled both to protein kinase A-dependent and protein kinase C-dependent systems.
    Journal of hypertension, 1998, Volume: 16, Issue:8

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Blood Pressure; Cardiomegaly; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Gene Expression; Glucagon; HSP70 Heat-Shock Proteins; Hypertension; In Vitro Techniques; Isoquinolines; Male; Myocardium; Naphthalenes; Perfusion; Protein Biosynthesis; Protein Kinase C; Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction; Sulfonamides

1998
N-acetyl-D-glucosamine induces germination in Candida albicans through a mechanism sensitive to inhibitors of cAMP-dependent protein kinase.
    Cellular signalling, 1998, Volume: 10, Issue:10

    Topics: Acetylglucosamine; Bucladesine; Candida albicans; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Glucagon; Isoquinolines; Morphogenesis; Sulfonamides

1998
Glucagon-like peptide-1 causes pancreatic duodenal homeobox-1 protein translocation from the cytoplasm to the nucleus of pancreatic beta-cells by a cyclic adenosine monophosphate/protein kinase A-dependent mechanism.
    Endocrinology, 2001, Volume: 142, Issue:5

    Topics: Animals; Biological Transport; Cell Nucleus; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Cytoplasm; Glucagon; Glucagon-Like Peptide 1; Glucose; Homeodomain Proteins; Insulin; Insulin Secretion; Isoquinolines; Peptide Fragments; Promoter Regions, Genetic; Protein Precursors; Rats; RNA, Messenger; Sulfonamides; Trans-Activators; Tumor Cells, Cultured

2001
NFAT regulates insulin gene promoter activity in response to synergistic pathways induced by glucose and glucagon-like peptide-1.
    Diabetes, 2002, Volume: 51, Issue:3

    Topics: Animals; Calcineurin; Calcineurin Inhibitors; Calcium; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DNA-Binding Proteins; Drug Synergism; Enzyme Inhibitors; Gene Expression Regulation; Glucagon; Glucagon-Like Peptide 1; Glucose; Insulin; Islets of Langerhans; Isoquinolines; NFATC Transcription Factors; Nuclear Proteins; Peptide Fragments; Promoter Regions, Genetic; Protein Precursors; Rats; Sulfonamides; Tacrolimus; Transcription Factors; Transcription, Genetic

2002
cAMP-activated protein kinase-independent potentiation of insulin secretion by cAMP is impaired in SUR1 null islets.
    Diabetes, 2002, Volume: 51, Issue:12

    Topics: Animals; ATP-Binding Cassette Transporters; Carbazoles; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Indoles; Insulin; Insulin Secretion; Islets of Langerhans; Isoquinolines; Mice; Mice, Knockout; Peptide Fragments; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Kinase C; Pyrroles; Receptors, Drug; Reference Values; Sulfonamides; Sulfonylurea Receptors

2002
Insulin and glucagon regulation of glutathione S-transferase expression in primary cultured rat hepatocytes.
    The Journal of pharmacology and experimental therapeutics, 2003, Volume: 305, Issue:1

    Topics: Animals; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Glucagon; Glutathione Transferase; Hepatocytes; Insulin; Isoquinolines; Male; Rats; Rats, Sprague-Dawley; Sulfonamides

2003
Differential activation mechanisms of Erk-1/2 and p70(S6K) by glucose in pancreatic beta-cells.
    Diabetes, 2003, Volume: 52, Issue:4

    Topics: Animals; Calcium; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glyburide; Humans; Islets of Langerhans; Isoquinolines; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Peptide Fragments; Phosphorylation; Proto-Oncogene Proteins c-raf; Rats; Rats, Sprague-Dawley; Ribosomal Protein S6 Kinases, 70-kDa; Sulfonamides; Verapamil

2003
Glucagon-like peptide-1 induces a cAMP-dependent increase of [Na+]i associated with insulin secretion in pancreatic beta-cells.
    American journal of physiology. Endocrinology and metabolism, 2003, Volume: 285, Issue:5

    Topics: Adenine; Adenylyl Cyclase Inhibitors; Animals; Calcium; Cricetinae; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Gadolinium; Glucagon; Glucagon-Like Peptide 1; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Isoquinolines; Male; Mesocricetus; Ouabain; Peptide Fragments; Protein Precursors; Sodium; Somatostatin; Sulfonamides; Tetrodotoxin

2003
Glucose stimulates the expression and activities of nitric oxide synthases in incubated rat islets: an effect counteracted by GLP-1 through the cyclic AMP/PKA pathway.
    Cell and tissue research, 2005, Volume: 319, Issue:2

    Topics: Animals; Bucladesine; Cyclic AMP; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Cyclic N-Oxides; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Free Radical Scavengers; Glucagon; Glucagon-Like Peptide 1; Glucose; Imidazoles; Insulin; Insulin Secretion; Islets of Langerhans; Isoquinolines; Male; Microdissection; Microscopy, Confocal; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peptide Fragments; Protein Kinase Inhibitors; Protein Precursors; Rats; Rats, Sprague-Dawley; Sulfonamides

2005
Glucagon Increases Beating Rate but Not Contractility in Rat Right Atrium. Comparison with Isoproterenol.
    PloS one, 2015, Volume: 10, Issue:7

    Topics: Animals; Atrial Function, Right; Calcium Signaling; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Glucagon; Heart Atria; Heart Rate; Isoproterenol; Isoquinolines; Male; Myocardial Contraction; Myocardium; Phosphodiesterase 3 Inhibitors; Phosphodiesterase 4 Inhibitors; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Sulfonamides

2015
PDK4 Deficiency Suppresses Hepatic Glucagon Signaling by Decreasing cAMP Levels.
    Diabetes, 2018, Volume: 67, Issue:10

    Topics: Animals; Blotting, Western; Cells, Cultured; Cyclic AMP; Glucagon; Gluconeogenesis; Glucose Tolerance Test; Hepatocytes; Isoquinolines; Liver; Male; Mice; Mice, Inbred C57BL; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Real-Time Polymerase Chain Reaction; Sulfonamides; Triglycerides

2018