Page last updated: 2024-09-04

glucagon and guanosine triphosphate

glucagon has been researched along with guanosine triphosphate in 146 studies

Compound Research Comparison

Studies
(glucagon)
Trials
(glucagon)
Recent Studies (post-2010)
(glucagon)
Studies
(guanosine triphosphate)
Trials
(guanosine triphosphate)
Recent Studies (post-2010) (guanosine triphosphate)
26,0391,4983,05414,728252,115

Research

Studies (146)

TimeframeStudies, this research(%)All Research%
pre-1990115 (78.77)18.7374
1990's27 (18.49)18.2507
2000's1 (0.68)29.6817
2010's2 (1.37)24.3611
2020's1 (0.68)2.80

Authors

AuthorsStudies
Fujimoto, M; Mihara, S; Okabayashi, T; Sugase, T; Tarui, S1
Cooper, B; Gregerman, RI; Partilla, JS1
Lad, PM; Lin, MC; Nicosia, S; Rodbell, M1
Hamet, P; Johnson, RA; Pilkis, SJ1
Hanoune, J; Mavier, P1
Hupka, AL; Sweat, FW; Wincek, TJ1
Bennett, V; Cuatrecasas, P; Jacobs, S2
Bennett, V; Cuatrecasas, P; Mong, L1
Helmreich, EJ; Pfeuffer, T; Zenner, HP1
Poupon, R1
Johnson, DG; Thompson, WJ; Williams, RH1
Guellaen, G; Hanoune, J; Lacombe, ML; Rene, E1
Tomasi, V1
Lad, PM; Rodbell, M; Welton, AF1
Lad, PM; Newby, AC; Nicosia, S; Rodbell, M; Welton, AF; Yamamura, H1
Sweat, FW; Yamashita, L2
Berman, MF; Lin, MC; Welton, AF1
Birnbaumer, L; Iyengar, R; Swartz, TL1
Birnbaumer, L; Iyengar, R2
Abramowitz, J; Birnbaumer, L; Iyengar, R1
Doberska, CA; Kennedy, EL; Martin, BR; Metcalfe, JC; Stein, JM1
Rodbell, M4
Gregerman, RI; Katz, MS; Kelly, TM; Piñeyro, MA1
Liang, CT; Sacktor, B; Takenawa, T1
Magnuson, T; Swislocki, NI; Tierney, J1
Hanoune, J; Pecker, F1
Lad, PM; Lin, MC; Londos, C; Rodbell, M; Welton, AF1
Gregerman, RI; Kalish, MI; Katz, MS; Piñeyro, MA1
Londos, C; Preston, MS2
Christophe, J; Dehaye, JP; Winand, J1
Kimura, N; Nagata, N; Nakane, K1
Londos, C; Rodbell, M1
Franks, DJ1
Criss, WE; Pradhan, TK; Wolff, J1
Lin, MC; Londos, C; Rendell, M; Rodbell, M; Salomon, Y1
Hanoune, J; Lacombe, ML; Pecker, F1
Haley, B; Lin, PC; Shoemaker, M1
Bataille, D; Capeau, J; Deterre, P; Dufour, M; LeNguyen, D; Lotersztajn, S; Mallat, A; Pavoine, C; Pecker, F; Rouot, B1
Authier, F; De Galle, B; Desbuquois, B1
Miyazaki, H; Post, SR; Tager, HS1
Brechler, V; Fischmeister, R; Garbarz, E; Hanf, R; Pavoine, C; Pecker, F1
Brighenti, L; Fabbri, E; Ottolenghi, C1
Akamatu, N; Shima, S1
Houslay, MD; Milligan, G; Palmer, T; Strassheim, D1
Houslay, MD; Palmer, TM1
Bataille, D; Brechler, V; Dufour, M; Le-Nguyen, D; Lotersztajn, S; Pavoine, C; Pecker, F; Roche, B1
Fernandez-Cruz, A; Fernandez-Durango, R; Sanchez, D1
Egidy, G; Galvagno, MA; Passeron, S; Paveto, C1
Das, MR; Hegde, AN1
Blackmore, PF; Exton, JH; Johnson, EH; Krone, PK; Lynch, CJ; Wange, RL1
Gurd, RS; McVittie, LD1
Kimura, N; Shimada, N4
Donner, DB; Kolhatkar, AA; Lipson, KE; Maki, RG1
Sheetz, MJ; Tager, HS1
Attramadal, H; Eikvar, L; Hansson, V1
García-Sáinz, JA; Hernández-Sotomayor, SM; Macías-Silva, M; Plebañski, M1
Brighenti, L; Fabbri, E; Gavioli, ME; Ottolenghi, C; Puviani, AC1
Akamatsu, N; Oikawa, S; Okeyama, N; Shima, S1
Herberg, JT; Iyengar, R2
Birnbaumer, L; Rojas, FJ1
Mason, JC; Tager, HS1
Martin, BR; Wong, SK1
Coy, DH; Hruby, VJ; Johnson, DG; McKee, RL; Pelton, JT; Sueiras-Diaz, J; Trivedi, D1
Bloom, AS; Hillard, CJ; Houslay, MD1
Donner, DB; Dorato, A; Kolhatkar, AA; Lipson, KE1
Ho, RJ; Ruiz, J; Shi, QH1
Floyd, G; Herberg, JT; Iyengar, R; Monsatirsky, B; Padrell, E; Premont, RT1
Bacchus, RA; Frandsen, EK1
Bégin-Heick, N; Welsh, J1
Camus, JC; Chatelain, P; Christophe, J; Robberecht, P; Waelbroeck, M1
Hansson, V; Jahnsen, T; Smith, AJ1
Bernstein, KJ; Triner, L; Verosky, M1
Anand-Srivastava, MB; Srivastava, AK1
Hodgins, DS; Kuo, JF; Kuo, WN1
Bitensky, MW; Keirns, JJ; Wheeler, MA1
Howell, SL; Montague, W1
Flawiá, MM; Torres, HN1
Birnbaumer, L; Goldfine, ID; Roth, J1
Birnbaumer, L; Pohl, SL1
Rodbell, M; Rubalcava, B1
Harwood, JP; Löw, H; Rodbell, M1
Birnbaumer, L1
Lin, MC; Rodbell, M; Salomon, Y1
Exton, JH; Johnson, RA; Park, CR; Pilkis, SJ1
Dalton, C; Hope, H; Sheppard, H1
Harwood, JP; Lin, MC; Londos, C; Rodbell, M; Salomon, Y; Schramm, M; Wolff, J1
Sweat, FW; Wincek, TJ1
Birnbaumer, L; Pohl, SL; Rodbell, M; Sundby, F1
Chambaut, AM; Hanoune, J; Leray, F1
Birnbaumer, L; Pohl, SL; Rodbell, M1
Gurd, RS; Hoosein, NM1
Hanski, E; Heyworth, CM; Houslay, MD1
Cooper, ME; Heyworth, CM; Houslay, MD; Payne, NJ; Wallace, AV; Wilson, SR1
Camus, JC; Chatelain, P; Christophe, J; Gillet, L; Robberecht, P; Waelbroeck, M1
Houslay, MD; Whetton, AD1
Abramowitz, J; Birnbaumer, L; Bordelon-Riser, M; Iyengar, R1
Dipple, I; Elliott, KR; Houslay, MD1
Amiranoff, B; Laburthe, M; Rosselin, G1
Houslay, MD1
Cooper, DM; Kempner, ES; Lad, PM; Londos, C; Nielsen, TB; Preston, MS; Rodbell, M; Schlegel, W1
Corin, RE; Donner, DB; Ferriola, P1
Greenberg, ML; Malbon, CC1
Peters, F; Pingoud, VA1
Horie, H; Matsuyama, T; Tarui, S1
Allgayer, H; Bachmann, W; Hepp, KD1
Martin, BR; Tolkovsky, AM1
Tkachuk, VA1
Iynedjian, PB; Salavert, A1
Birnbaumer, L; Desmier, M; Hanoune, J; Stengel, D1
Korn, AP; Ottensmeyer, FP1
Kiss, Z; Tkachuk, VA1
Birnbaumer, L; Iyengar, R; Mintz, PW; Swartz, TL1
Johnson, RA1
Chatelain, P; Christophe, J; De Neef, P; Deschodt-Lanckman, M; König, W; Robberecht, P1
Martin, BR1
Breton, M; Colard, O1
Richards, JM; Swislocki, NI1
Hynie, S; Klenerová, V1
Clark, CM; Fricke, RF; Queener, SF1
Ciani, S; Ribalet, B1
Houslay, MD; Livingstone, C; MacDonald, C; Willett, B1
Janssens, PA; Kleineke, JW1
Caro, JF; Ravindra, R1
Cortinovis, C; Klimek, F; Nogueira, E1
Borovok, N; Maltzeva, E; Spassov, V; Zlatanov, I1
Allende, G; García-Sáinz, JA; Piña, E; Robles-Flores, M1
Dianzani, MU; Losa, GA; Paradisi, L1
Cantore, ML; Castilla, R; Passeron, S; Zelada, A1
Seidler, FJ; Slotkin, TA; Zeiders, JL1
Beckner, SK1
Fukuyama, Y; Gotoh, M; Horio, Y; Inanobe, A; Kurachi, Y; Yoshimoto, Y1
Derkach, KV; Kuznetsova, LA; Pertseva, MN; Plesneva, SA; Shpakov, AO; Uspenskaia, ZI1
Berggren, PO; Birkenfeld, AL; Cabrera, O; Choi, CS; Kibbey, RG; Lee, HY; Li, C; Pongratz, RL; Shulman, GI; Stanley, C; Zhao, X1
Jia, G; Sowers, JR1
Aigner, S; Mutlu, B; Puigserver, P; Sathe, S; Sharabi, K; Tavares, CDJ; Yeo, GW1

Reviews

5 review(s) available for glucagon and guanosine triphosphate

ArticleYear
Guanyl nucleotide regulation of hormonally-responsive adenylyl cyclases.
    Molecular and cellular endocrinology, 1979, Volume: 16, Issue:3

    Topics: Adenylyl Cyclases; Animals; Binding Sites; Cell Membrane; Cholera Toxin; Enzyme Activation; Erythrocytes; Glucagon; GTP Phosphohydrolases; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Triphosphate; Hormones; Liver; Rats; Receptors, Cell Surface; Turkeys

1979
Hormone-sensitive adenylyl cyclases. Useful models for studying hormone receptor functions in cell-free systems.
    Biochimica et biophysica acta, 1973, Sep-10, Volume: 300, Issue:2

    Topics: Adenosine Triphosphate; Adenylyl Cyclases; Adipose Tissue; Adrenocorticotropic Hormone; Animals; Calcium; Cations, Divalent; Cell Membrane; Cell-Free System; Epinephrine; Fluorides; Glucagon; Guanosine Triphosphate; Kidney Medulla; Kinetics; Liver; Luteinizing Hormone; Models, Biological; Propranolol; Prostaglandins; Receptors, Cell Surface; Secretin; Thyrotropin; Vasopressins

1973
Does insulin exert certain of its actions through a distinct species of guanine nucleotide regulatory protein?
    Biochemical Society transactions, 1984, Volume: 12, Issue:5

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine Diphosphate Ribose; Adenosine Triphosphate; Adenylyl Cyclases; Animals; Cyclic AMP; Enzyme Activation; Glucagon; GTP-Binding Proteins; Guanosine Triphosphate; Insulin

1984
Nobel Lecture. Signal transduction: evolution of an idea.
    Bioscience reports, 1995, Volume: 15, Issue:3

    Topics: Adenylyl Cyclases; Adipose Tissue; Animals; Cross-Linking Reagents; Detergents; Fluorides; Glucagon; GTP-Binding Proteins; Guanosine Triphosphate; Humans; Liver; Models, Biological; Nobel Prize; Receptors, Cell Surface; Second Messenger Systems; Signal Transduction

1995
Signal transduction: evolution of an idea.
    Environmental health perspectives, 1995, Volume: 103, Issue:4

    Topics: Adenylyl Cyclases; Animals; Cell Communication; Glucagon; GTP-Binding Proteins; Guanosine Triphosphate; Hormones; Humans; Liver; Receptors, Cell Surface; Second Messenger Systems; Signal Transduction

1995

Other Studies

141 other study(ies) available for glucagon and guanosine triphosphate

ArticleYear
Rapid radioimmunoassay for guanosine 3',5'-cyclic monophosphate using tritiated ligand.
    Journal of biochemistry, 1975, Volume: 78, Issue:1

    Topics: Animals; Binding, Competitive; Cyclic AMP; Cyclic GMP; Glucagon; Guanosine Triphosphate; Humans; Hydrogen-Ion Concentration; Male; Micropore Filters; Phosphoric Diester Hydrolases; Radioimmunoassay; Rats; Salts; Tritium

1975
Human fat cell adenylate cyclase. Enzyme characterization and guanine nucleotide effects on epinephrine responsiveness in cell membranes.
    Biochimica et biophysica acta, 1976, Aug-12, Volume: 445, Issue:1

    Topics: Adenosine Triphosphate; Adenylyl Cyclases; Adipose Tissue; Adrenocorticotropic Hormone; Adult; Cell Membrane; Epinephrine; Female; Fluorides; Glucagon; Guanine Nucleotides; Guanosine Triphosphate; Humans; Hydrogen-Ion Concentration; Magnesium; Male; Temperature

1976
Effects of GTP on binding of (3H) glucagon to receptors in rat hepatic plasma membranes.
    The Journal of biological chemistry, 1977, Apr-25, Volume: 252, Issue:8

    Topics: Animals; Binding, Competitive; Cell Membrane; Glucagon; Guanosine Triphosphate; Hydrogen-Ion Concentration; Kinetics; Liver; Rats; Receptors, Cell Surface

1977
Liver membrane adenylate cyclase. Synergistic effects of anions on fluoride, glucagon, and guanyl nucleotide stimulation.
    The Journal of biological chemistry, 1975, Aug-25, Volume: 250, Issue:16

    Topics: Adenosine Triphosphatases; Adenylyl Cyclases; Animals; Anions; Azides; Cell Membrane; Cyanides; Enzyme Activation; Fluorides; Glucagon; Guanine Nucleotides; Guanosine Triphosphate; Kinetics; Liver; Rats

1975
Adenylate cyclase from rat-liver plasma membrane: inhibition by mersalyl and other mercurial derivatives.
    European journal of biochemistry, 1975, Nov-15, Volume: 59, Issue:2

    Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Adenylyl Cyclase Inhibitors; Animals; Cell Membrane; Chloromercuribenzoates; Dose-Response Relationship, Drug; Enzyme Activation; Female; Fluorides; Glucagon; Guanosine Triphosphate; Kinetics; Liver; Magnesium; Mercaptoethanol; Mercury; Mersalyl; Organomercury Compounds; Organometallic Compounds; Rats

1975
Stimulation of adenylate cyclase from isolated hepatocytes and Kupffer cells.
    The Journal of biological chemistry, 1975, Nov-25, Volume: 250, Issue:22

    Topics: Adenylyl Cyclases; Animals; Calcium; Fluorides; Glucagon; Guanosine Triphosphate; Hyaluronoglucosaminidase; In Vitro Techniques; Iron; Isoproterenol; Kupffer Cells; Liver; Male; Microbial Collagenase; Microscopy, Phase-Contrast; Peptides; Perfusion; Prostaglandins E; Rats; Secretin

1975
Irreversible stimulation of adenylate cyclase activity of fat cell membranes of phosphoramidate and phosphonate analogs of GTP.
    The Journal of membrane biology, 1975, Volume: 23, Issue:3-4

    Topics: Adenosine Triphosphate; Adenylyl Cyclases; Adipose Tissue; Adrenocorticotropic Hormone; Aniline Compounds; Animals; Binding, Competitive; Cell Membrane; Diphosphates; Dithiothreitol; Edetic Acid; Fluorides; Glucagon; Guanine Nucleotides; Guanosine Triphosphate; Hydroxylamines; Isoproterenol; Mercury; Organometallic Compounds; Phosphates; Rats; Sodium

1975
Mechanism of activation of adenylate cyclase by Vibrio cholerae enterotoxin. Relations to the mode of activation by hormones.
    The Journal of membrane biology, 1975, Nov-07, Volume: 24, Issue:2

    Topics: Adenylyl Cyclases; Adipose Tissue; Adrenocorticotropic Hormone; Animals; Anti-Bacterial Agents; Enterotoxins; Enzyme Activation; Glucagon; Guanosine Triphosphate; Guinea Pigs; Hormones; Ileum; Intestinal Mucosa; Isoproterenol; Kinetics; Liver; Magnesium; Male; Organ Specificity; Rats; Receptors, Drug; Vibrio cholerae

1975
Signal transfer from hormone receptor to adenylate cyclase.
    Current topics in cellular regulation, 1976, Volume: 10

    Topics: Adenylyl Cyclases; Adipose Tissue; Animals; Binding Sites; Calcium; Catecholamines; Cell Membrane; Enzyme Activation; Fluorides; Glucagon; Guanosine Triphosphate; Insulin; Kinetics; Lipids; Liver; Magnesium; Membranes; Myocardium; Protein Binding; Rabbits; Rats; Receptors, Cell Surface

1976
Activity of human adenylate cyclase from human fat cell membranes.
    Biomedicine / [publiee pour l'A.A.I.C.I.G.], 1975, Dec-20, Volume: 23, Issue:10

    Topics: Adenosine Triphosphate; Adenylyl Cyclases; Adipose Tissue; Adrenocorticotropic Hormone; Adult; Aged; Animals; Cell Membrane; Cyclic AMP; Cytosine Nucleotides; Enzyme Activation; Epinephrine; Fluorides; Glucagon; Guanosine Triphosphate; Humans; Middle Aged; Rats

1975
Hormonal regulation of pancreatic islet adenyl cyclase.
    Biochemistry, 1976, Apr-20, Volume: 15, Issue:8

    Topics: Adenylyl Cyclases; Adrenocorticotropic Hormone; Animals; Cell Membrane; Cholecystokinin; Fluorides; Glucagon; Growth Hormone; Guanosine Triphosphate; Insulin; Islets of Langerhans; Isoproterenol; Kinetics; Male; Phentolamine; Propranolol; Prostaglandins E; Rats; Secretin

1976
Transformation of the beta2 adrenoceptor in normal rat liver into a beta1 type in Zajdela hepatoma.
    Nature, 1976, Jul-01, Volume: 262, Issue:5563

    Topics: Adenylyl Cyclases; Animals; Carcinoma, Hepatocellular; Catecholamines; Enzyme Activation; Epinephrine; Female; Fluorides; Glucagon; Guanosine Triphosphate; Liver; Liver Neoplasms; Neoplasms, Experimental; Rats; Receptors, Adrenergic

1976
Prostaglandin E1 as an intercellular regulator of cyclic AMP levels.
    Experimental cell biology, 1976, Volume: 44, Issue:3-6

    Topics: Adenylyl Cyclases; Animals; Cell Membrane; Cyclic AMP; Epinephrine; Fluorides; Glucagon; Guanosine Triphosphate; Inflammation; Liver; Lymphocytes; Phospholipases; Prostaglandins E; Rats; Receptors, Cell Surface; Receptors, Prostaglandin; Trypsin

1976
Evidence for distinct guanine nucleotide sites in the regulation of the glucagon receptor and of adenylate cyclase activity.
    The Journal of biological chemistry, 1977, Sep-10, Volume: 252, Issue:17

    Topics: Adenylyl Cyclases; Animals; Bacillus cereus; Cell Membrane; Egtazic Acid; Enzyme Activation; Glucagon; Guanosine Triphosphate; Kinetics; Liver; Phospholipases; Rats; Receptors, Cell Surface

1977
Solubilization and separation of the glucagon receptor and adenylate cyclase in guanine nucleotide-sensitive states.
    The Journal of biological chemistry, 1977, Sep-10, Volume: 252, Issue:17

    Topics: Adenylyl Cyclases; Animals; Cell Membrane; Enzyme Activation; Glucagon; Guanosine Triphosphate; Liver; Rats; Receptors, Cell Surface; Receptors, Drug; Solubility

1977
Prostaglandin E1 effects on cyclic AMP and glycogen metabolism in rat liver.
    Biochemical and biophysical research communications, 1978, Jun-14, Volume: 82, Issue:3

    Topics: Adenylyl Cyclases; Animals; Cyclic AMP; Glucagon; Glucose; Guanosine Triphosphate; Liver; Liver Glycogen; Male; Prostaglandins E; Rats

1978
Essential role of GTP in the expression of adenylate cyclase activity after cholera toxin treatment.
    Journal of cyclic nucleotide research, 1978, Volume: 4, Issue:3

    Topics: Adenylyl Cyclases; Animals; Cell Membrane; Cholera Toxin; Enzyme Activation; Fluorides; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Liver; NAD; Peptide Fragments; Rats

1978
Coupling of glucagon receptor to adenylyl cyclase. Requirement of a receptor-related guanyl nucleotide binding site for coupling of receptor to the enzyme.
    The Journal of biological chemistry, 1979, Feb-25, Volume: 254, Issue:4

    Topics: Adenylyl Cyclases; Animals; Cell Membrane; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Liver; Rats; Receptors, Cell Surface

1979
Coupling of the glucagon receptor to adenylyl cyclase by GDP: evidence for two levels of regulation of adenylyl cyclase.
    Proceedings of the National Academy of Sciences of the United States of America, 1979, Volume: 76, Issue:7

    Topics: Adenylyl Cyclases; Animals; Glucagon; GTP Phosphohydrolases; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; In Vitro Techniques; Liver; Rats; Receptors, Cell Surface

1979
Transient complexes. A new structural model for the activation of adenylate cyclase by hormone receptors (guanine nucleotides/irradiation inactivation).
    The Biochemical journal, 1979, Nov-15, Volume: 184, Issue:2

    Topics: Adenylyl Cyclases; Animals; Cell Membrane; Enzyme Activation; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hormones; Liver; Macromolecular Substances; Models, Biological; Rats; Receptors, Cell Surface

1979
On the mechanism of activation of fat cell adenylate cyclase by guanine nucleotides. An explanation for the biphasic inhibitory and stimulatory effects of the nucleotides and the role of hormones.
    The Journal of biological chemistry, 1975, Aug-10, Volume: 250, Issue:15

    Topics: Adenylyl Cyclases; Adipose Tissue; Adrenocorticotropic Hormone; Animals; Cell Membrane; Enzyme Activation; Epinephrine; Fluorides; Glucagon; Guanine Nucleotides; Guanosine Triphosphate; Hydrogen-Ion Concentration; Kinetics; Magnesium; Rats; Time Factors

1975
Activation of epinephrine and glucagon-sensitive adenylate cyclases of rat liver by cytosol protein factors. Role in loss of enzyme activities during preparation of particulate fractions, quantitation and partial characterization.
    Journal of cyclic nucleotide research, 1978, Volume: 4, Issue:5

    Topics: Adenylyl Cyclases; Animals; Cytosol; Enzyme Activation; Epinephrine; Female; Glucagon; Guanosine Triphosphate; Hot Temperature; Liver; Male; Proteins; Rats

1978
Potentiation of GTP of hormone-responsive adenylate cyclase in renal cortex plasma membrane preparations.
    Biochemical and biophysical research communications, 1978, Dec-29, Volume: 85, Issue:4

    Topics: Adenylyl Cyclases; Animals; Cell Membrane; Enzyme Activation; Epinephrine; Glucagon; Guanosine Triphosphate; Kidney Cortex; Kidney Tubules, Proximal; Kinetics; Male; Parathyroid Hormone; Prostaglandins E; Rabbits

1978
Properties of rat liver plasma membrane adenylate cyclase after chromatography on O-diethylaminoethyl-cellulose and agarose-hexane-GTP.
    Archives of biochemistry and biophysics, 1977, Volume: 179, Issue:1

    Topics: Adenylyl Cyclases; Animals; Cell Membrane; Chromatography, Affinity; Glucagon; Guanosine Triphosphate; Hypophysectomy; Kinetics; Liver; Rats; Surface-Active Agents

1977
Activation of epinephrine-sensitive adenylate cyclase in rat liver by cytosolic protein-nucleotide complex.
    The Journal of biological chemistry, 1977, Apr-25, Volume: 252, Issue:8

    Topics: Adenylyl Cyclases; Animals; Cell Membrane; Cytosol; Enzyme Activation; Epinephrine; Female; Fluorides; Glucagon; Guanosine Triphosphate; Kinetics; Liver; Proteins; Rats

1977
Reversible activation of hepatic adenylate cyclase by guanyl-5'-yl-(alpha,beta-methylene)diphosphonate and guanyl-5'-yl imidodiphosphate.
    The Journal of biological chemistry, 1977, Aug-10, Volume: 252, Issue:15

    Topics: Adenylyl Cyclases; Animals; Cell Membrane; Diphosphonates; Enzyme Activation; Glucagon; Guanine Nucleotides; Guanosine Triphosphate; Kinetics; Liver; Protein Binding; Rats

1977
Epinephrine-and glucagon-sensitive adenylate cyclases of rat liver during aging. Evidence for membrane instability associated with increased enzymatic activity.
    Biochimica et biophysica acta, 1977, Aug-11, Volume: 483, Issue:2

    Topics: Adenylyl Cyclases; Aging; Animals; Cell Membrane; Dose-Response Relationship, Drug; Epinephrine; Female; Fluorides; Glucagon; Guanosine Triphosphate; Kinetics; Liver; Male; Rats; Sex Factors

1977
Regulation by glucagon and divalent cations of inhibition of hepatic adenylate cyclase by adenosine.
    The Journal of biological chemistry, 1977, Sep-10, Volume: 252, Issue:17

    Topics: Adenosine; Adenosine Triphosphate; Adenylyl Cyclase Inhibitors; Animals; Cell Membrane; Enzyme Activation; Glucagon; Guanosine Triphosphate; Kinetics; Liver; Magnesium; Manganese; Rats

1977
Activation of the hepatic adenylate cyclase system by divalent cations.
    The Journal of biological chemistry, 1977, Sep-10, Volume: 252, Issue:17

    Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Cell Membrane; Enzyme Activation; Glucagon; Guanosine Triphosphate; Kinetics; Liver; Magnesium; Manganese; Rats

1977
Adenylate cyclase activity in hepatic plasma membranes from obese-hyperglycaemic mice [proceedings].
    Biochemical Society transactions, 1977, Volume: 5, Issue:4

    Topics: Adenylyl Cyclases; Animals; Cell Membrane; Enzyme Activation; Fluorides; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hyperglycemia; Liver; Mice; Mice, Obese

1977
The stimulation of rat liver adenylate cyclase by prostaglandins E1 and E2.
    Biochemical and biophysical research communications, 1976, May-17, Volume: 70, Issue:2

    Topics: Adenylyl Cyclases; Animals; Cell Membrane; Dose-Response Relationship, Drug; Enzyme Activation; Glucagon; Guanosine Triphosphate; Kinetics; Liver; Prostaglandins E; Rats

1976
Activation by GTP of liver adenylate cyclase in the presence of high concentrations of ATP.
    Biochemical and biophysical research communications, 1976, Jun-21, Volume: 70, Issue:4

    Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Cell Membrane; Enzyme Activation; Fluorides; Glucagon; Guanosine Triphosphate; Kinetics; Liver; Rats

1976
Regulation of hepatic adenylate cyclase by glucagon, GTP, divalent cations, and adenosine.
    Metabolism: clinical and experimental, 1976, Volume: 25, Issue:11 Suppl 1

    Topics: Adenosine; Adenylyl Cyclases; Animals; Cations, Divalent; Cell Membrane; Glucagon; Guanosine Triphosphate; Liver; Rats

1976
Cholera toxin and adenylate cyclase: properties of the activated enzyme in liver plasma membranes.
    Canadian journal of biochemistry, 1976, Volume: 54, Issue:11

    Topics: Adenylyl Cyclases; Animals; Bacterial Toxins; Cell Membrane; Enzyme Activation; Epinephrine; Fluorides; Glucagon; Guanosine Triphosphate; Kinetics; Liver; Magnesium; Male; Mice; Prostaglandins E; Vibrio cholerae

1976
Regulation of adenylate cyclase in two rat liver cell lines, 3C4 and 62.
    Enzyme, 1976, Volume: 21, Issue:6

    Topics: Adenylyl Cyclases; Animals; Cell Line; Culture Media; Epinephrine; Fluorides; Glucagon; Guanosine Triphosphate; Kinetics; Prostaglandins A; Prostaglandins E; Rats

1976
Activation of adenylate cyclase by phosphoramidate and phosphonate analogs of GTP: possible role of covalent enzyme-substrate intermediates in the mechanism of hormonal activation.
    Proceedings of the National Academy of Sciences of the United States of America, 1975, Volume: 72, Issue:5

    Topics: Adenylyl Cyclases; Adipose Tissue; Amides; Animals; Chromatography, Affinity; Enzyme Activation; Fluorides; Glucagon; Guanosine Triphosphate; Isoproterenol; Kinetics; Male; Organophosphonates; Rats

1975
The hepatic adenylate cyclase system. I. Evidence for transition states and structural requirements for guanine nucloetide activiation.
    The Journal of biological chemistry, 1975, Jun-10, Volume: 250, Issue:11

    Topics: Adenylyl Cyclases; Animals; Binding, Competitive; Cell Membrane; Enzyme Activation; Glucagon; Guanine Nucleotides; Guanosine Triphosphate; Kinetics; Liver; Magnesium; Protein Binding; Rats; Structure-Activity Relationship; Time Factors

1975
The epinephrine-sensitive adenylate cyclase of rat liver plasma membranes. Role of guanyl nucleotides.
    The Journal of biological chemistry, 1975, Jun-25, Volume: 250, Issue:12

    Topics: Adenylyl Cyclases; Animals; Cell Membrane; Enzyme Activation; Epinephrine; Female; Fluorides; Glucagon; Guanine Nucleotides; Guanosine Triphosphate; Kinetics; Liver; Magnesium; Rats; Structure-Activity Relationship

1975
Identification of the guanine binding domain peptide of the GTP-binding site of glucagon.
    Protein science : a publication of the Protein Society, 1992, Volume: 1, Issue:7

    Topics: Adenine; Adenine Nucleotides; Adenosine; Amino Acid Sequence; Binding Sites; Binding, Competitive; Chromatography, High Pressure Liquid; Chymotrypsin; Electrophoresis, Polyacrylamide Gel; Glucagon; Guanosine Triphosphate; Humans; Kinetics; Molecular Sequence Data; Peptide Fragments

1992
Role of G protein beta gamma subunits in the regulation of the plasma membrane Ca2+ pump.
    The Journal of biological chemistry, 1992, Feb-05, Volume: 267, Issue:4

    Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Blotting, Western; Ca(2+) Mg(2+)-ATPase; Calcium-Transporting ATPases; Cell Line, Transformed; Cell Membrane; Cells, Cultured; Cholera Toxin; Electrophoresis, Polyacrylamide Gel; Glucagon; GTP-Binding Proteins; Guanosine Triphosphate; Liver; Rats; Sodium Fluoride

1992
Ligand-mediated internalization of glucagon receptors in intact rat liver.
    Endocrinology, 1992, Volume: 131, Issue:1

    Topics: Adenylyl Cyclases; Amidohydrolases; Animals; Cell Fractionation; Cell Membrane; Cross-Linking Reagents; Dinitrofluorobenzene; Electrophoresis, Polyacrylamide Gel; Glucagon; Golgi Apparatus; Guanosine Triphosphate; Liver; Male; Molecular Weight; Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase; Rats; Rats, Inbred Strains; Receptors, Gastrointestinal Hormone; Receptors, Glucagon

1992
Identification of a Mg(2+)- and guanyl nucleotide-dependent glucagon receptor cycle by use of permeabilized canine hepatocytes.
    The Journal of biological chemistry, 1992, Dec-25, Volume: 267, Issue:36

    Topics: Animals; Cell Membrane Permeability; Cells, Cultured; Dogs; Glucagon; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Kinetics; Liver; Magnesium; Models, Biological; Receptors, Gastrointestinal Hormone; Receptors, Glucagon; Saponins; Temperature

1992
Inhibition by glucagon of the cGMP-inhibited low-Km cAMP phosphodiesterase in heart is mediated by a pertussis toxin-sensitive G-protein.
    The Journal of biological chemistry, 1992, Aug-05, Volume: 267, Issue:22

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine Triphosphate; Adenylyl Cyclases; Animals; Cyclic AMP; Cyclic GMP; Cytosol; Glucagon; GTP-Binding Proteins; Guanine Nucleotides; Guanosine Triphosphate; Guanylate Cyclase; Heart Ventricles; Intercellular Signaling Peptides and Proteins; Kinetics; Myocardium; Peptides; Pertussis Toxin; Rana esculenta; Virulence Factors, Bordetella; Wasp Venoms

1992
Inhibition of adenylate cyclase of catfish and rat hepatocyte membranes by 9-(tetrahydro-2-furyl)adenine (SQ 22536).
    Journal of enzyme inhibition, 1991, Volume: 5, Issue:2

    Topics: Adenine; Adenylyl Cyclase Inhibitors; Animals; Cell Membrane; Cells, Cultured; Epinephrine; Female; Glucagon; Guanosine Triphosphate; Ictaluridae; Isoproterenol; Kinetics; Liver; Male; Norepinephrine; Phenylephrine; Rats; Sodium Fluoride; Species Specificity

1991
Multiple controls by adenosine receptors on the adenylate cyclase in the rat hepatic membrane.
    Japanese journal of pharmacology, 1990, Volume: 53, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Cell Membrane; Cyclic AMP; Glucagon; Guanosine Triphosphate; In Vitro Techniques; Liver; Male; Phenylisopropyladenosine; Rats; Receptors, Purinergic; Sodium Chloride

1990
Alterations in G-protein expression and the hormonal regulation of adenylate cyclase in the adipocytes of obese (fa/fa) Zucker rats.
    The Biochemical journal, 1991, May-15, Volume: 276 ( Pt 1)

    Topics: Adenylyl Cyclases; Adipose Tissue; Animals; Cell Membrane; Cells, Cultured; Glucagon; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Kinetics; Macromolecular Substances; Male; Obesity; Rats; Rats, Zucker; Secretin; Thyrotropin

1991
Determination of G-protein levels, ADP-ribosylation by cholera and pertussis toxins and the regulation of adenylyl cyclase activity in liver plasma membranes from lean and genetically diabetic (db/db) mice.
    Biochimica et biophysica acta, 1991, Oct-21, Volume: 1097, Issue:3

    Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Blotting, Western; Cell Membrane; Cholera Toxin; Colforsin; Diabetes Mellitus, Experimental; Glucagon; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Liver; Male; Mice; Mice, Inbred C57BL; Pertussis Toxin; Virulence Factors, Bordetella

1991
Glucagon-(19-29) exerts a biphasic action on the liver plasma membrane Ca2+ pump which is mediated by G proteins.
    The Journal of biological chemistry, 1990, Jun-15, Volume: 265, Issue:17

    Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Calcium; Calcium-Transporting ATPases; Cell Membrane; Cholera Toxin; Female; Glucagon; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Kinetics; Liver; Magnesium; Peptide Fragments; Pertussis Toxin; Rats; Rats, Inbred Strains; Sodium Fluoride; Thionucleotides; Virulence Factors, Bordetella

1990
Identification of glucagon receptors in rat retina.
    Journal of neurochemistry, 1990, Volume: 54, Issue:4

    Topics: Animals; Binding Sites; Binding, Competitive; Glucagon; Guanosine Triphosphate; Kinetics; Osmolar Concentration; Rats; Receptors, Gastrointestinal Hormone; Receptors, Glucagon; Retina

1990
A guanine nucleotide-sensitive, glucagon-stimulated adenylyl cyclase in Candida albicans: effect of glucagon on cell morphology.
    Biochemical and biophysical research communications, 1990, Mar-30, Volume: 167, Issue:3

    Topics: Adenylyl Cyclases; Candida albicans; Enzyme Activation; Glucagon; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Magnesium; Thionucleotides

1990
Glucagon and p21 ras enhance the phosphorylation of the same 38-kilodalton membrane protein from rat liver cells.
    Molecular and cellular biology, 1990, Volume: 10, Issue:6

    Topics: Animals; Electrophoresis, Polyacrylamide Gel; Glucagon; Guanosine Diphosphate; Guanosine Triphosphate; Humans; Kinetics; Liver; Male; Membrane Proteins; Molecular Weight; Oncogene Protein p21(ras); Peptide Mapping; Phosphoproteins; Phosphorylation; Rats; Rats, Inbred Strains; Recombinant Proteins

1990
Guanine nucleotide binding regulatory proteins and adenylate cyclase in livers of streptozotocin- and BB/Wor-diabetic rats. Immunodetection of Gs and Gi with antisera prepared against synthetic peptides.
    The Journal of clinical investigation, 1989, Volume: 83, Issue:6

    Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Aluminum; Angiotensin II; Animals; Catalysis; Cell Line; Cell Membrane; Cholera Toxin; Colforsin; Diabetes Mellitus, Experimental; Enzyme Activation; Fluorine; Glucagon; GTP-Binding Proteins; Guanosine Triphosphate; Immune Sera; Injections, Intraperitoneal; Liver; Male; Peptide Fragments; Pertussis Toxin; Rats; Rats, Inbred BB; Rats, Inbred Strains; Virulence Factors, Bordetella

1989
Stabilization of soluble active rat liver glucagon receptor.
    Archives of biochemistry and biophysics, 1989, Aug-15, Volume: 273, Issue:1

    Topics: Animals; Binding, Competitive; Drug Stability; Glucagon; Guanosine Triphosphate; Liver; Male; Rats; Rats, Inbred Strains; Receptors, Gastrointestinal Hormone; Receptors, Glucagon; Salts; Solubility

1989
Direct interaction between membrane-associated nucleoside diphosphate kinase and GTP-binding protein(Gs), and its regulation by hormones and guanine nucleotides.
    Biochemical and biophysical research communications, 1988, Feb-29, Volume: 151, Issue:1

    Topics: Adenylyl Cyclases; Animals; Cell Membrane; Glucagon; GTP-Binding Proteins; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Immunoassay; Isoproterenol; Liver; Nucleoside-Diphosphate Kinase; Phosphotransferases; Rats

1988
Divalent cations regulate glucagon binding. Evidence for actions on receptor-Ns complexes and on receptors uncoupled from Ns.
    Biochemistry, 1988, Feb-23, Volume: 27, Issue:4

    Topics: Animals; Cations, Divalent; Cell Membrane; Edetic Acid; Glucagon; Guanosine Triphosphate; Kinetics; Liver; Magnesium; Male; Rats; Rats, Inbred Strains; Receptors, Gastrointestinal Hormone; Receptors, Glucagon

1988
Receptor-linked proteolysis of membrane-bound glucagon yields a membrane-associated hormone fragment.
    The Journal of biological chemistry, 1988, Jun-15, Volume: 263, Issue:17

    Topics: Animals; Chromatography, High Pressure Liquid; Dogs; Electrophoresis, Polyacrylamide Gel; Glucagon; Guanosine Triphosphate; Molecular Weight; Peptide Fragments; Protease Inhibitors; Receptors, Gastrointestinal Hormone; Receptors, Glucagon

1988
Mechanisms of glucagon-induced homologous and heterologous desensitization of adenylate cyclase in membranes and whole Sertoli cells of the rat.
    Endocrinology, 1988, Volume: 123, Issue:2

    Topics: Adenosine Triphosphate; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Cell Membrane; Cyclic AMP; Drug Tolerance; Follicle Stimulating Hormone; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Male; Pertussis Toxin; Phenylisopropyladenosine; Protein Kinases; Rats; Rats, Inbred Strains; Sertoli Cells; Sodium Fluoride; Virulence Factors, Bordetella

1988
Homologous and heterologous beta-adrenergic desensitization in hepatocytes. Additivity and effect of pertussis toxin.
    Biochimica et biophysica acta, 1988, Dec-09, Volume: 972, Issue:3

    Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Drug Interactions; Enzyme Activation; Female; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hypothyroidism; Isoproterenol; Liver; Pertussis Toxin; Propranolol; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Tetradecanoylphorbol Acetate; Urea; Vasopressins; Virulence Factors, Bordetella

1988
Adenylate cyclase of catfish hepatocyte membranes: basal properties and sensitivity to catecholamines and glucagon.
    Molecular and cellular endocrinology, 1988, Volume: 60, Issue:2-3

    Topics: Adenosine Triphosphate; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Catecholamines; Catfishes; Cell Membrane; Enzyme Activation; Epinephrine; Glucagon; Guanosine Triphosphate; Isoproterenol; Kinetics; Liver; Magnesium; Norepinephrine; Phentolamine; Phenylephrine; Propranolol; Receptors, Adrenergic, beta; Temperature

1988
Effects of chronic propranolol treatment on hepatic adenylate cyclase system in the rat.
    The Journal of toxicological sciences, 1987, Volume: 12, Issue:3

    Topics: Adenosine Diphosphate; Adenylyl Cyclases; Adrenergic beta-Antagonists; Animals; Blood Glucose; Cell Membrane; Electrophoresis, Polyacrylamide Gel; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Liver; Liver Glycogen; Male; Propanolamines; Propranolol; Rats; Rats, Inbred Strains; Sodium Fluoride

1987
Covalent labeling of the hepatic glucagon receptor.
    Methods in enzymology, 1985, Volume: 109

    Topics: Adenylyl Cyclases; Animals; Glucagon; Guanosine Triphosphate; Liver; Membranes; Rats; Receptors, Cell Surface; Receptors, Glucagon

1985
Regulation of glucagon receptor binding. Lack of effect of Mg and preferential role for GDP.
    The Journal of biological chemistry, 1985, Jul-05, Volume: 260, Issue:13

    Topics: Adenylyl Cyclases; Animals; Cholera Toxin; Glucagon; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Liver; Magnesium; Rats; Receptors, Cell Surface; Receptors, Glucagon; Thionucleotides

1985
Differential susceptibility to GTP formed from added GDP via membrane-associated nucleoside diphosphate kinase of GTP-sensitive adenylate cyclases achieved by hormone and cholera toxin.
    Biochemical and biophysical research communications, 1985, Aug-30, Volume: 131, Issue:1

    Topics: Adenylyl Cyclases; Animals; Cell Membrane; Cholera Toxin; Enzyme Activation; Glucagon; Guanosine Diphosphate; Guanosine Triphosphate; Liver; Male; Nucleoside-Diphosphate Kinase; Phosphotransferases; Rats; Rats, Inbred Strains

1985
Identification of distinct receptor complexes that account for high-and low-affinity glucagon binding to hepatic plasma membranes.
    Proceedings of the National Academy of Sciences of the United States of America, 1985, Volume: 82, Issue:20

    Topics: Animals; Cell Membrane; Chromatography, Affinity; Chromatography, Gel; Dogs; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Liver; Receptors, Cell Surface; Receptors, Glucagon

1985
GTP-activated GTP binding protein(Gs) in membranes achieved by hormone plus GDP does not serve as a substrate for ADP-ribosylation by cholera toxin.
    Biochemical and biophysical research communications, 1986, Jan-29, Volume: 134, Issue:2

    Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Cholera Toxin; Enzyme Activation; Glucagon; GTP-Binding Proteins; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Triphosphate; Molecular Weight; Nucleoside Diphosphate Sugars; Rats; Receptors, Cell Surface; Receptors, Glucagon

1986
Activation of rat liver adenylate cyclase by guanosine 5'-[beta,gamma-imido]triphosphate and glucagon. Existence of reversibly and irreversibly activated states of the stimulatory GTP-binding protein.
    The Biochemical journal, 1986, Feb-01, Volume: 233, Issue:3

    Topics: Adenylyl Cyclases; Animals; Cyclic AMP; Enzyme Activation; Glucagon; GTP-Binding Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Liver; Rats; Thionucleotides

1986
Receptor binding and adenylate cyclase activities of glucagon analogues modified in the N-terminal region.
    Biochemistry, 1986, Apr-08, Volume: 25, Issue:7

    Topics: Adenylyl Cyclases; Animals; Binding, Competitive; Cell Membrane; Glucagon; Guanosine Triphosphate; Iodine Radioisotopes; Kinetics; Liver; Male; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Glucagon; Structure-Activity Relationship

1986
Effects of delta 9-tetrahydrocannabinol on glucagon receptor coupling to adenylate cyclase in rat liver plasma membranes.
    Biochemical pharmacology, 1986, Aug-15, Volume: 35, Issue:16

    Topics: Adenylyl Cyclases; Animals; Cannabinoids; Cell Membrane; Colforsin; Dronabinol; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Liver; Male; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Glucagon; Sodium Fluoride

1986
N-ethylmaleimide uncouples the glucagon receptor from the regulatory component of adenylyl cyclase.
    Biochemistry, 1986, Sep-23, Volume: 25, Issue:19

    Topics: Adenylyl Cyclases; Animals; Cell Membrane; Ethylmaleimide; Glucagon; GTP-Binding Proteins; Guanosine Triphosphate; Kinetics; Liver; Male; Rats; Rats, Inbred Strains; Receptors, Gastrointestinal Hormone; Receptors, Glucagon

1986
A dose-response study of forskolin, stimulatory hormone, and guanosine triphosphate analog on adenylate cyclase from several sources.
    Archives of biochemistry and biophysics, 1986, Nov-15, Volume: 251, Issue:1

    Topics: Adenylyl Cyclases; Adipose Tissue; Adrenocorticotropic Hormone; Animals; Cell Membrane; Colforsin; Drug Synergism; Enzyme Activation; Epinephrine; Erythrocyte Membrane; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hormones; Liver; Rabbits; Rats; Solubility

1986
The hepatic glucagon receptor: a comparative study of the regulatory and structural properties.
    Endocrinology, 1987, Volume: 120, Issue:6

    Topics: Adenylate Cyclase Toxin; Animals; Biological Assay; Cell Membrane; Chickens; Cross-Linking Reagents; Glucagon; GTP-Binding Proteins; Guanosine Triphosphate; Liver; Magnesium; Magnesium Chloride; Molecular Weight; Rabbits; Rats; Receptors, Gastrointestinal Hormone; Receptors, Glucagon; Species Specificity; Virulence Factors, Bordetella

1987
Glucagon receptor binding, dissociation and degradation in rat liver plasma membranes studied by a microperifusion method.
    Biochimica et biophysica acta, 1987, Jun-15, Volume: 929, Issue:1

    Topics: Animals; Cell Membrane; Glucagon; Guanosine Triphosphate; Kinetics; Liver; Peptide Hydrolases; Protein Binding; Rats; Rats, Inbred Strains; Receptors, Gastrointestinal Hormone; Receptors, Glucagon

1987
The regulation of adenylate cyclase in liver membranes of lean and obese mice.
    Molecular and cellular endocrinology, 1988, Volume: 59, Issue:3

    Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Cell Membrane; Cholera Toxin; Enzyme Activation; Glucagon; Guanosine Triphosphate; Isoproterenol; Liver; Magnesium; Magnesium Chloride; Male; Mice; Mice, Inbred C57BL; Norepinephrine; Obesity; Pertussis Toxin; Propranolol; Virulence Factors, Bordetella; Yohimbine

1988
Modulation by n-alkanols of rat cardiac adenylate cyclase activity.
    The Journal of membrane biology, 1986, Volume: 93, Issue:1

    Topics: Adenylyl Cyclases; Alcohols; Animals; Cell Membrane; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Myocardium; Rats; Secretin; Sodium Fluoride; Structure-Activity Relationship

1986
Membrane-bound adenylate cyclase activity in the testis of the blue fox.
    Archives of andrology, 1985, Volume: 14, Issue:1

    Topics: Adenylyl Cyclases; Alprostadil; Animals; Chorionic Gonadotropin; Dose-Response Relationship, Drug; Follicle Stimulating Hormone; Foxes; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Magnesium; Male; Manganese; Membranes; Testis; Time Factors

1985
Effect of halothane on rat liver adenylate cyclase: role of cytosol components.
    Anesthesia and analgesia, 1985, Volume: 64, Issue:5

    Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Cell Membrane; Cytosol; Enzyme Activation; Glucagon; Guanosine Triphosphate; Halothane; Hot Temperature; In Vitro Techniques; Liver; Male; Protein Denaturation; Rats; Rats, Inbred Strains; Serum Albumin, Bovine; Trypsin

1985
Streptozotocin-induced diabetes and hormone sensitivity of adenylate cyclase in rat myocardial sarcolemma, aorta and liver.
    Biochemical pharmacology, 1985, Jun-01, Volume: 34, Issue:11

    Topics: Adenylyl Cyclases; Animals; Aorta; Catecholamines; Colforsin; Corpus Striatum; Diabetes Mellitus, Experimental; Diterpenes; Glucagon; Guanosine Triphosphate; Hormones; Liver; Male; Myocardium; Rats; Rats, Inbred Strains; Sarcolemma

1985
Regulation by various hormones and agents of adenosine-3',5'-monophosphate levels in islets of Langerhans of rats.
    Biochemical pharmacology, 1974, May-01, Volume: 23, Issue:9

    Topics: Adenine; Adrenergic beta-Antagonists; Adrenocorticotropic Hormone; Animals; Cresols; Cyclic AMP; Epinephrine; Glucagon; Glucose; Guanosine Triphosphate; Hormones; In Vitro Techniques; Islets of Langerhans; Isoproterenol; Leucine; Phenformin; Phenoxybenzamine; Phentolamine; Propanolamines; Propranolol; Propylamines; Prostaglandins; Rats; Receptors, Adrenergic; Secretin; Sotalol; Theophylline; Thyrotropin; Tolbutamide; Tritium

1974
Isolation of cyclic AMP and cyclic GMP by thin-layer chromatography. Application to assay of adenylate cyclase, guanylate cyclase, and cyclic nucleotide phosphodiesterase.
    Analytical biochemistry, 1974, Volume: 61, Issue:2

    Topics: Adenine; Adenosine Triphosphate; Adenylyl Cyclases; Alloxan; Animals; Anura; Carbon Radioisotopes; Cell Membrane; Chromatography, Ion Exchange; Chromatography, Thin Layer; Cyclic AMP; Cyclic GMP; Evaluation Studies as Topic; Glucagon; Guanine; Guanosine Triphosphate; Guanylate Cyclase; Kinetics; Liver; Lung; Methods; Phosphoric Diester Hydrolases; Photoreceptor Cells; Rats; Time Factors; Tritium

1974
Adenylate cyclase activity in isolated rat islets of Langerhans. Effects of agents which alter rates of insulin secretion.
    Biochimica et biophysica acta, 1973, Aug-17, Volume: 320, Issue:1

    Topics: Adenylyl Cyclases; Animals; Arginine; Epinephrine; Fluorides; Glucagon; Glucose; Glyburide; Guanosine Triphosphate; Hydrogen-Ion Concentration; In Vitro Techniques; Islets of Langerhans; Isoproterenol; Kinetics; Leucine; Male; Norepinephrine; Nucleotides; Phenoxybenzamine; Phosphorus Radioisotopes; Potassium; Propranolol; Prostaglandins; Rats; Xylitol

1973
Activation of membrane-bound adenylate cyclase by glucagon in Neurospora crassa.
    Proceedings of the National Academy of Sciences of the United States of America, 1972, Volume: 69, Issue:10

    Topics: Adenosine Triphosphate; Adenylyl Cyclases; Carbon Isotopes; Cell Membrane; Detergents; Drug Interactions; Enzyme Activation; Glucagon; Glycogen Synthase; Guanosine Triphosphate; Kinetics; Manganese; Neurospora; Neurospora crassa; Osmolar Concentration; Phosphorus Isotopes; Phosphorylases; Protein Binding; Stimulation, Chemical

1972
Glucagon receptors in -cells. Binding of 125 I-glucagon and activation of adenylate cyclase.
    The Journal of biological chemistry, 1972, Feb-25, Volume: 247, Issue:4

    Topics: Adenoma, Islet Cell; Adenosine Monophosphate; Adenosine Triphosphate; Adenylyl Cyclases; Animals; Antigens; Binding Sites; Cricetinae; Enzyme Activation; Glucagon; Guanosine Triphosphate; Immune Sera; Intestines; Iodine Isotopes; Pancreas; Phosphorus Isotopes; Protein Binding; Receptors, Drug; Subcellular Fractions; Swine; Time Factors; Tritium

1972
Relation of glucagon-specific binding sites to glucagon-dependent stimulation of adenylyl cyclase activity in plasma membranes of rat liver.
    The Journal of biological chemistry, 1973, Mar-25, Volume: 248, Issue:6

    Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Binding Sites; Cell Membrane; Cyclic AMP; Glucagon; Guanosine Triphosphate; Histidine; Iodine Isotopes; Kinetics; Liver; Phosphorus Isotopes; Purine Nucleotides; Rats; Receptors, Cell Surface; Receptors, Drug; Time Factors; Tritium

1973
The role of acidic phospholipids in glucagon action on rat liver adenylate cyclase.
    The Journal of biological chemistry, 1973, Jun-10, Volume: 248, Issue:11

    Topics: Adenylyl Cyclases; Animals; Bacillus cereus; Binding Sites; Binding, Competitive; Cell Membrane; Clostridium perfringens; Enzyme Activation; Glucagon; Guanosine Triphosphate; Histidine; Hydrogen-Ion Concentration; Iodine Isotopes; Liver; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipases; Phospholipids; Protein Binding; Rats; Sphingomyelins; Structure-Activity Relationship

1973
The problem of identifying the glucagon receptor.
    Federation proceedings, 1973, Volume: 32, Issue:8

    Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Binding Sites; Cell Membrane; Cyclic AMP; Enzyme Activation; Fluorides; Glucagon; Guanosine Triphosphate; Kinetics; Liver; Models, Biological; Rats; Receptors, Cell Surface

1973
Stimulatory and inhibitory effects of guanyl nucleotides on fat cell adenylate cyclase.
    The Journal of biological chemistry, 1973, Sep-10, Volume: 248, Issue:17

    Topics: Adenosine Triphosphate; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adipose Tissue; Adrenocorticotropic Hormone; Animals; Catalysis; Cell Membrane; Centrifugation, Density Gradient; Cyclic AMP; Enzyme Activation; Epididymis; Epinephrine; Glucagon; Guanine Nucleotides; Guanosine Triphosphate; Inosine Nucleotides; Male; Rats; Structure-Activity Relationship; Uracil Nucleotides

1973
Evidence for interdependent action of glucagon and nucleotides on the hepatic adenylate cyclase system.
    The Journal of biological chemistry, 1974, Jan-10, Volume: 249, Issue:1

    Topics: Adenine Nucleotides; Adenylyl Cyclases; Animals; Binding Sites; Cell Membrane; Chromatography, Ion Exchange; Cyclic AMP; Glucagon; Guanosine Triphosphate; Iodine Radioisotopes; Kinetics; Liver; Phosphorus Radioisotopes; Protein Binding; Rats; Receptors, Cell Surface; Time Factors

1974
Effects of glucagon on cyclic AMP and carbohydrate metabolism in livers from diabetic rats.
    Biochimica et biophysica acta, 1974, Mar-20, Volume: 343, Issue:1

    Topics: Adenylyl Cyclases; Animals; Calcium; Carbohydrate Metabolism; Cell Membrane; Cyclic AMP; Diabetes Mellitus; Diabetes Mellitus, Experimental; Glucagon; Guanosine Triphosphate; Kinetics; Liver; Magnesium; Male; Ouabain; Phosphoric Diester Hydrolases; Rats; Streptozocin; Theophylline

1974
Regulation of hormone stimulation of adipose tissue lipolysis by guanosine triphosphate.
    Archives of biochemistry and biophysics, 1974, Volume: 163, Issue:1

    Topics: Adenosine Triphosphate; Adipose Tissue; Adrenocorticotropic Hormone; Animals; Cyclic AMP; Cyclic GMP; Cytosine Nucleotides; Epididymis; Fatty Acids, Nonesterified; Glucagon; Guanine Nucleotides; Guanosine Triphosphate; Inosine Nucleotides; Kinetics; Lipid Mobilization; Male; Norepinephrine; Prostaglandins; Rats; Spectrometry, Fluorescence; Theophylline; Thymine Nucleotides; Time Factors; Uracil Nucleotides

1974
5'-Guanylylimidodiphosphate, a potent activator of adenylate cyclase systems in eukaryotic cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1974, Volume: 71, Issue:8

    Topics: Adenylyl Cyclases; Adipose Tissue; Adrenal Gland Neoplasms; Adrenal Glands; Allosteric Regulation; Animals; Anura; Cattle; Cell Line; Cell Membrane; Enzyme Activation; Epinephrine; Erythrocytes; Escherichia coli; Fluorides; Glucagon; Guanine Nucleotides; Guanosine Triphosphate; Liver; Propranolol; Rats; Salmon; Stimulation, Chemical; Thyroid Gland

1974
The stimulation of hepatic adenylate cyclase by prostaglandin E1.
    Biochemical and biophysical research communications, 1973, Nov-16, Volume: 55, Issue:2

    Topics: Adenylyl Cyclases; Aluminum; Animals; Chromatography; Chromatography, Ion Exchange; Dogs; Enzyme Activation; Fluorides; Glucagon; Guanosine Triphosphate; Kinetics; Liver; Mice; Phosphorus Radioisotopes; Prostaglandins; Rabbits; Rats; Species Specificity

1973
The glucagon-sensitive adenylate cyclase system in plasma membranes of rat liver. VII. Hormonal stimulation: reversibility and dependence on concentration of free hormone.
    The Journal of biological chemistry, 1972, Apr-10, Volume: 247, Issue:7

    Topics: Adenosine Triphosphate; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Allosteric Regulation; Animals; Binding Sites; Cell Membrane; Drug Synergism; Fluorides; Glucagon; Guanosine Triphosphate; Histidine; Iodine Isotopes; Liver; Osmolar Concentration; Phosphorus Isotopes; Rats; Structure-Activity Relationship; Time Factors

1972
Role of GTP in epinephrine and glucagon activation of adenyl cyclase of liver plasma membrane.
    Biochemical and biophysical research communications, 1972, Sep-26, Volume: 48, Issue:6

    Topics: Adenylyl Cyclases; Adrenal Glands; Animals; Cell Membrane; Enzyme Activation; Epinephrine; Female; Fluorides; Glucagon; Guanosine Triphosphate; In Vitro Techniques; Liver; Phosphorus Isotopes; Rats; Tritium

1972
Characteristics of glucagon action on the hepatic adenylate cyclase system.
    The Biochemical journal, 1971, Volume: 125, Issue:3

    Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Binding Sites; Enzyme Activation; Glucagon; Guanosine Triphosphate; Liver; Models, Chemical; Phospholipids; Rats; Structure-Activity Relationship

1971
Identification of glucagon receptors in rat brain.
    Proceedings of the National Academy of Sciences of the United States of America, 1984, Volume: 81, Issue:14

    Topics: Adenylyl Cyclases; Animals; Binding Sites; Brain; Enzyme Activation; Glucagon; Guanosine Triphosphate; Insulin; Liver; Male; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Glucagon; Subcellular Fractions; Tissue Distribution

1984
Islet-activating protein blocks glucagon desensitization in intact hepatocytes.
    The Biochemical journal, 1984, Aug-15, Volume: 222, Issue:1

    Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Animals; Bacterial Proteins; Bacterial Toxins; Cell Membrane; Cyclic AMP; Glucagon; Guanosine Triphosphate; In Vitro Techniques; Liver; Male; Pertussis Toxin; Rats; Rats, Inbred Strains; Virulence Factors, Bordetella

1984
Glucagon-stimulated GTP hydrolysis in rat liver plasma membranes.
    FEBS letters, 1980, Aug-11, Volume: 117, Issue:1

    Topics: Adenylyl Cyclases; Animals; Cell Membrane; Dose-Response Relationship, Drug; Glucagon; GTP Phosphohydrolases; Guanosine Triphosphate; Kinetics; Liver; Phosphoric Monoester Hydrolases; Rats

1980
Selective alteration of secretin-stimulated cardiac adenylate cyclase activity in streptozotocin-diabetic rats.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1983, Volume: 15, Issue:12

    Topics: Adenylyl Cyclases; Animals; Diabetes Mellitus, Experimental; Glucagon; Guanosine Triphosphate; Isoproterenol; Male; Myocardium; Rats; Rats, Inbred Strains; Secretin; Sodium Fluoride; Streptozocin

1983
The effect of vinblastine on the glucagon, basal and GTP-stimulated states of the adenylate cyclase from rat liver plasma membranes.
    FEBS letters, 1980, Mar-10, Volume: 111, Issue:2

    Topics: Adenylyl Cyclases; Animals; Cell Membrane; Dose-Response Relationship, Drug; Glucagon; Guanosine Triphosphate; Liver; Male; Rats; Receptors, Cell Surface; Vinblastine

1980
Hormone receptor-mediated stimulation of adenylyl cyclase systems. Nucleotide effects and analysis in terms of a simple two-state model for the basic receptor-affected enzyme.
    The Journal of biological chemistry, 1980, Apr-25, Volume: 255, Issue:8

    Topics: Adenylyl Cyclases; Animals; Cell Membrane; Enzyme Activation; Epoprostenol; Glucagon; Guanine Nucleotides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Liver; Rats; Receptors, Cell Surface

1980
Guanosine 5'-triphosphate and guanosine 5'-[beta gamma-imido]triphosphate effect a collision coupling mechanism between the glucagon receptor and catalytic unit of adenylate cyclase.
    The Biochemical journal, 1980, Mar-15, Volume: 186, Issue:3

    Topics: Adenylyl Cyclases; Animals; Benzyl Alcohols; Cell Membrane; Cricetinae; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; In Vitro Techniques; Kinetics; Ligands; Liver; Male; Rats; Receptors, Cell Surface; Sodium Chloride; Trypsin

1980
Differential effects of guanine nucleotides on the first step of VIP and glucagon action in membranes from liver cells.
    Biochemical and biophysical research communications, 1980, Sep-16, Volume: 96, Issue:1

    Topics: Adenylyl Cyclases; Animals; Cell Membrane; Gastrointestinal Hormones; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Liver; Rats; Receptors, Cell Surface; Vasoactive Intestinal Peptide

1980
Mobile receptor and collision coupling mechanisms for the activation of adenylate cyclase by glucagon.
    Advances in cyclic nucleotide research, 1981, Volume: 14

    Topics: Adenylyl Cyclases; Animals; Cell Membrane; Enzyme Activation; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Lipid Bilayers; Liver; Rats; Receptors, Cell Surface; Receptors, Glucagon; Trypsin

1981
The structure of adenylate cyclase systems.
    Advances in cyclic nucleotide research, 1981, Volume: 14

    Topics: Adenylyl Cyclases; Adipose Tissue; Animals; Cell Membrane; Erythrocytes; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Liver; Macromolecular Substances; Molecular Weight; Rats; Receptors, Cell Surface; Turkeys

1981
Hepatic glucagon-receptor complexes lose sensitivity to the dissociating effect of GTP.
    The Journal of biological chemistry, 1982, Feb-25, Volume: 257, Issue:4

    Topics: Animals; Cell Membrane; Glucagon; Guanosine Triphosphate; Kinetics; Liver; Male; Protein Binding; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Glucagon

1982
3,3',5-triiodothyronine administration in vivo modulates the hormone-sensitive adenylate cyclase system of rat hepatocytes.
    The Journal of clinical investigation, 1982, Volume: 69, Issue:2

    Topics: Adenylyl Cyclases; Animals; Benzyl Alcohols; Cholera Toxin; Cyclic AMP; Epinephrine; Female; Glucagon; Guanosine Triphosphate; Hormones; Hyperthyroidism; Isoproterenol; Liver; Pindolol; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Triiodothyronine; Triiodothyronine, Reverse

1982
A critical interpretation of experiments on binding of peptide hormone to specific receptors by computer modelling.
    Biochimica et biophysica acta, 1982, Feb-25, Volume: 714, Issue:3

    Topics: Animals; Computers; Glucagon; Guanosine Triphosphate; Insulin; Liver; Models, Biological; Receptor, Insulin; Receptors, Cell Surface; Receptors, Glucagon

1982
[Recent findings on glucagon receptors and isolation of glicentin].
    Nihon rinsho. Japanese journal of clinical medicine, 1981, Volume: 39, Issue:9

    Topics: Animals; Glucagon; Guanosine Triphosphate; Proglucagon; Protein Precursors; Receptors, Cell Surface; Receptors, Glucagon

1981
Increased dose-response relationship of liver plasma membrane adenylate cyclase to glucagon stimulation in diabetic rats. A possible role of the guanyl nucleotide-binding regulatory protein.
    Diabetologia, 1982, Volume: 22, Issue:6

    Topics: Adenylyl Cyclases; Animals; Cell Membrane; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Glucagon; GTP-Binding Proteins; Guanosine Triphosphate; Insulin; Liver; Male; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Sodium Fluoride; Streptozocin

1982
Hormone receptor modulates the regulatory component of adenylyl cyclase by reducing its requirement for Mg2+ and enhancing its extent of activation by guanine nucleotides.
    Proceedings of the National Academy of Sciences of the United States of America, 1982, Volume: 79, Issue:17

    Topics: Adenylyl Cyclases; Animals; Cell Line; Cell Membrane; Ethylmaleimide; Glucagon; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Kinetics; Liver; Lymphoma; Magnesium; Mice; Neoplasms, Experimental; Receptors, Cell Surface; Receptors, Glucagon; Thionucleotides

1982
The glucagon receptor from liver can be functionally fused to caudate nucleus adenylate cyclase.
    FEBS letters, 1982, Dec-27, Volume: 150, Issue:2

    Topics: Adenylyl Cyclases; Animals; Caudate Nucleus; Cell Membrane; Enzyme Activation; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Liver; Rats; Receptors, Cell Surface; Receptors, Glucagon

1982
Regulation of adenylate cyclase by hormones and guanine nucleotides in normal, desensitized, and resensitized rabbit heart.
    Advances in myocardiology, 1982, Volume: 3

    Topics: Adenylyl Cyclases; Animals; Catecholamines; Dose-Response Relationship, Drug; Enzyme Activation; Epinephrine; Female; Glucagon; Guanine Nucleotides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Histamine; Isoproterenol; Male; Myocardium; Rabbits; Receptors, Adrenergic, beta; Sarcolemma

1982
Structural analysis of the hepatic glucagon receptor. Identification of a guanine nucleotide-sensitive hormone-binding region.
    The Journal of biological chemistry, 1984, Apr-25, Volume: 259, Issue:8

    Topics: Acetylglucosaminidase; Animals; Cell Membrane; Glucagon; Guanosine Triphosphate; Kinetics; Liver; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Molecular Weight; Rats; Receptors, Cell Surface; Receptors, Glucagon

1984
Effects of glucagon, dexamethasone and triiodothyronine on phosphoenolpyruvate carboxykinase (GTP) synthesis and mRNA level in rat liver cells.
    European journal of biochemistry, 1984, Dec-17, Volume: 145, Issue:3

    Topics: Animals; Cell-Free System; Cytosol; Dexamethasone; Electrophoresis; Glucagon; Guanosine Triphosphate; In Vitro Techniques; Liver; Male; Phosphoenolpyruvate Carboxykinase (GTP); Protein Biosynthesis; Rats; Rats, Inbred Strains; RNA, Messenger; Time Factors; Triiodothyronine

1984
Forskolin regulation of liver membrane adenylyl cyclase.
    European journal of biochemistry, 1983, Oct-17, Volume: 136, Issue:1

    Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Cell Membrane; Chemical Phenomena; Chemistry; Colforsin; Diterpenes; Enzyme Activation; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Liver; Rats; Sodium Fluoride

1983
A model for the three-dimensional structure of glucagon.
    Journal of theoretical biology, 1983, Dec-07, Volume: 105, Issue:3

    Topics: Glucagon; Guanosine Triphosphate; Hydrogen Bonding; Models, Molecular; Molecular Conformation

1983
Guanine-nucleotide-dependent inhibition of adenylate cyclase of rabbit heart by glucagon.
    European journal of biochemistry, 1984, Jul-16, Volume: 142, Issue:2

    Topics: Adenylyl Cyclase Inhibitors; Animals; Benzyl Alcohol; Benzyl Alcohols; Enzyme Activation; Ethanol; Female; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Male; Myocardium; Rabbits; Rats; Rats, Inbred Strains

1984
Divalent cation-induced desensitization of glucagon-stimulable adenylyl cyclase in rat liver plasma membrane. GTP-dependent stimulation by glucagon.
    The Journal of biological chemistry, 1980, Dec-25, Volume: 255, Issue:24

    Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Cations, Divalent; Cell Membrane; Edetic Acid; Enzyme Activation; Glucagon; Guanosine Triphosphate; Kinetics; Liver; Rats

1980
Changes in pH sensitivity of adenylate cyclase specifically induced by fluoride and vanadate.
    Archives of biochemistry and biophysics, 1982, Oct-01, Volume: 218, Issue:1

    Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Enzyme Activation; Fluorides; Glucagon; Guanosine Triphosphate; Hydrogen-Ion Concentration; Liver; Magnesium; Manganese; Rats; Sodium Fluoride; Vanadates; Vanadium

1982
Secretin and VIP-stimulated adenylate cyclase from rat heart. I. General properties and structural requirements for enzyme activation.
    Pflugers Archiv : European journal of physiology, 1980, Volume: 389, Issue:1

    Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Dose-Response Relationship, Drug; Enzyme Activation; Gastrointestinal Hormones; Glucagon; Guanosine Triphosphate; In Vitro Techniques; Isoproterenol; Magnesium; Male; Myocardium; Rats; Secretin; Structure-Activity Relationship; Vasoactive Intestinal Peptide

1980
Transient receptor coupling in the activation of rat liver plasma-membrane adenylate cyclase by glucagon.
    Biochemical Society transactions, 1981, Volume: 9, Issue:1

    Topics: Adenylyl Cyclases; Animals; Binding Sites; Cell Membrane; Enzyme Activation; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Liver; Rats

1981
Rat liver plasma membrane phospholipids methylation; its absence of direct relationship to adenylate cyclase activities.
    Biochemical and biophysical research communications, 1981, Aug-14, Volume: 101, Issue:3

    Topics: Adenylyl Cyclases; Animals; Cell Membrane; Glucagon; Guanosine Triphosphate; In Vitro Techniques; Liver; Membrane Lipids; Methylation; Methyltransferases; Phosphatidylethanolamine N-Methyltransferase; Phospholipids; Rats; Sodium Fluoride

1981
Mechanism of molybdate activation of adenylate cyclase.
    Biochimica et biophysica acta, 1981, Dec-04, Volume: 678, Issue:2

    Topics: Adenylyl Cyclases; Animals; Cell Membrane; Enzyme Activation; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hydrogen-Ion Concentration; Kinetics; Liver; Molybdenum; Rats; Sodium Fluoride

1981
Effects of dimethyl sulfoxide and other dipolar aprotic solvents on rat hepatic adenylate cyclase. Potentiating effects on glucagon and guanylylimidodiphosphate stimulation.
    Naunyn-Schmiedeberg's archives of pharmacology, 1980, Volume: 310, Issue:3

    Topics: Adenylyl Cyclases; Animals; Dimethyl Sulfoxide; Drug Synergism; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Liver; Rats; Solvents; Stimulation, Chemical; Time Factors

1980
Cardiac adenylate cyclase: kinetics of synergistic activation by guanosine-5'-triphosphate (GTP) and glucagon.
    Journal of molecular and cellular cardiology, 1980, Volume: 12, Issue:6

    Topics: Adenylyl Cyclases; Animals; Drug Synergism; Enzyme Activation; Glucagon; Guanosine Triphosphate; Kinetics; Male; Myocardium; Rats

1980
Characterization of the G protein coupling of a glucagon receptor to the KATP channel in insulin-secreting cells.
    The Journal of membrane biology, 1994, Volume: 142, Issue:3

    Topics: Adenosine Triphosphate; Animals; Cholera Toxin; Cricetinae; Electrophysiology; Glucagon; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Magnesium; Membrane Potentials; Patch-Clamp Techniques; Potassium Channels; Rats; Receptors, Glucagon; Tumor Cells, Cultured

1994
Analysis of the adenylate cyclase signalling system, and alterations induced by culture with insulin, in a novel SV40-DNA-immortalized hepatocyte cell line (P9 cells).
    The Biochemical journal, 1994, Jun-15, Volume: 300 ( Pt 3)

    Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Alprostadil; Animals; Cell Line; Cell Transformation, Viral; Colforsin; Glucagon; GTP-Binding Proteins; Guanosine Triphosphate; Insulin; Liver; Male; Rats; Rats, Sprague-Dawley; Receptor, Insulin; Signal Transduction

1994
Hormone-induced rise in cytosolic Ca2+ in axolotl hepatocytes: extracellular origin and control by cAMP.
    The American journal of physiology, 1993, Volume: 265, Issue:5 Pt 1

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Ambystoma mexicanum; Animals; Calcium; Cells, Cultured; Cyclic AMP; Cytosol; Epinephrine; Glucagon; Guanosine Triphosphate; Inositol 1,4,5-Trisphosphate; Isoproterenol; Kinetics; Liver; Phentolamine; Propranolol; Thionucleotides; Vasotocin

1993
Insulin stimulates GDP release from G proteins in the rat and human liver plasma membranes.
    Journal of cellular biochemistry, 1993, Volume: 53, Issue:3

    Topics: Adult; Animals; Cell Membrane; Glucagon; GTP-Binding Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Humans; Insulin; Liver; Male; Rats; Rats, Sprague-Dawley

1993
Adenylate cyclase activity in microdissected rat liver tissue: periportal to pericentral activity gradient.
    Hepatology (Baltimore, Md.), 1993, Volume: 18, Issue:1

    Topics: Adenylyl Cyclases; Angiotensin II; Animals; Chlorides; Cholera Toxin; Colforsin; Cyclic AMP; Glucagon; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Lithium; Lithium Chloride; Liver; Male; Rats; Rats, Sprague-Dawley; Sodium Fluoride

1993
Effect of insulin and glucagon on the mobility of ESR-probes incorporated in rat liver plasma membranes.
    The International journal of biochemistry, 1993, Volume: 25, Issue:7

    Topics: Adenylyl Cyclases; Animals; Butylated Hydroxytoluene; Caprylates; Cell Membrane; Cyclic N-Oxides; Dinoprostone; Electron Spin Resonance Spectroscopy; Enzyme Activation; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Insulin; Kinetics; Liver; Membrane Fluidity; Rats; Rats, Wistar; Spin Labels

1993
Cross-talk between glucagon- and adenosine-mediated signalling systems in rat hepatocytes: effects on cyclic AMP-phosphodiesterase activity.
    The Biochemical journal, 1995, Dec-15, Volume: 312 ( Pt 3)

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylate Cyclase Toxin; Animals; Cell Membrane; Glucagon; Guanosine Triphosphate; Liver; Male; Pertussis Toxin; Phenylisopropyladenosine; Rats; Rats, Wistar; Receptors, Purinergic P1; Signal Transduction; Virulence Factors, Bordetella

1995
Enzymatic, biophysical and ultrastructural changes of plasma membranes in chemical-induced rat hepatoma.
    Cell biochemistry and function, 1995, Volume: 13, Issue:4

    Topics: Adenylyl Cyclases; Animals; Cell Membrane; Freeze Fracturing; Glucagon; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Lipid Metabolism; Liver Neoplasms, Experimental; Male; Membrane Proteins; Methyltransferases; Rats; Rats, Inbred F344; Spin Labels

1995
Reassessment of the effect of glucagon and nucleotides on Candida albicans germ tube formation.
    Cellular and molecular biology (Noisy-le-Grand, France), 1996, Volume: 42, Issue:4

    Topics: Acetylglucosamine; Candida albicans; Cyclic AMP; Glucagon; Guanosine Triphosphate

1996
Ontogeny of regulatory mechanisms for beta-adrenoceptor control of rat cardiac adenylyl cyclase: targeting of G-proteins and the cyclase catalytic subunit.
    Journal of molecular and cellular cardiology, 1997, Volume: 29, Issue:2

    Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Age Factors; Animals; Animals, Newborn; Body Weight; Carbachol; Cell Membrane; Colforsin; Drug Hypersensitivity; Female; Glucagon; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; GTP-Binding Proteins; Guanosine Triphosphate; Heart; Isoproterenol; Male; Manganese; Membrane Proteins; Muscarinic Agonists; Myocardium; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Time Factors

1997
G-protein activation by chemokines.
    Methods in enzymology, 1997, Volume: 288

    Topics: Animals; Bacterial Toxins; Chemokines; Epinephrine; Glucagon; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine Triphosphate; Interleukin-2; Lymphocytes; Membrane Proteins; Protein Binding; Receptors, Chemokine; Signal Transduction

1997
Somatostatin induces hyperpolarization in pancreatic islet alpha cells by activating a G protein-gated K+ channel.
    FEBS letters, 1999, Feb-12, Volume: 444, Issue:2-3

    Topics: Acetylcholine; Animals; Electrophysiology; Female; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Glucagon; GTP-Binding Proteins; Guanosine Triphosphate; Immunohistochemistry; Ion Channel Gating; Islets of Langerhans; Mice; Mice, Inbred Strains; Patch-Clamp Techniques; Pertussis Toxin; Potassium Channels; Potassium Channels, Inwardly Rectifying; RNA, Messenger; Somatostatin; Tolbutamide; Virulence Factors, Bordetella

1999
[The hormone-sensitive adenylyl cyclase system of the ciliate Dileptus anser].
    Tsitologiia, 2002, Volume: 44, Issue:11

    Topics: Adenylyl Cyclases; Animals; Ciliophora; Enzyme Activation; Epinephrine; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Protein Synthesis Inhibitors; Serotonin; Structure-Activity Relationship

2002
Mitochondrial GTP insensitivity contributes to hypoglycemia in hyperinsulinemia hyperammonemia by inhibiting glucagon release.
    Diabetes, 2014, Volume: 63, Issue:12

    Topics: Amino Acids; Animals; Glucagon; Glucagon-Secreting Cells; Glucose Clamp Technique; Glutamate Dehydrogenase; Guanosine Triphosphate; Humans; Hyperammonemia; Hyperinsulinism; Hypoglycemia; Insulin; Insulin Secretion; Insulin-Secreting Cells; Mice; Mice, Transgenic; Mitochondria; Mutation; Syndrome

2014
Interaction of islet α-cell and β-cell in the regulation of glucose homeostasis in HI/HA syndrome patients with the GDH(H454Y) mutation.
    Diabetes, 2014, Volume: 63, Issue:12

    Topics: Amino Acids; Animals; Glucagon; Glucagon-Secreting Cells; Glutamate Dehydrogenase; Guanosine Triphosphate; Humans; Hyperammonemia; Hyperinsulinism; Hypoglycemia; Insulin; Insulin Secretion; Insulin-Secreting Cells; Mitochondria

2014
Transcriptome-wide analysis of PGC-1α-binding RNAs identifies genes linked to glucagon metabolic action.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 09-08, Volume: 117, Issue:36

    Topics: Adenosine Triphosphate; Animals; Calcium-Binding Proteins; Cells, Cultured; Gene Expression Profiling; Gene Expression Regulation; Glucagon; Gluconeogenesis; Glucose; Guanosine Triphosphate; Hepatocytes; Liver; Male; Metabolomics; Mice; Mice, Inbred C57BL; Mitochondrial Membrane Transport Proteins; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Protein Binding; Transcriptome

2020