glucagon has been researched along with guanosine triphosphate in 146 studies
Studies (glucagon) | Trials (glucagon) | Recent Studies (post-2010) (glucagon) | Studies (guanosine triphosphate) | Trials (guanosine triphosphate) | Recent Studies (post-2010) (guanosine triphosphate) |
---|---|---|---|---|---|
26,039 | 1,498 | 3,054 | 14,728 | 25 | 2,115 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 115 (78.77) | 18.7374 |
1990's | 27 (18.49) | 18.2507 |
2000's | 1 (0.68) | 29.6817 |
2010's | 2 (1.37) | 24.3611 |
2020's | 1 (0.68) | 2.80 |
Authors | Studies |
---|---|
Fujimoto, M; Mihara, S; Okabayashi, T; Sugase, T; Tarui, S | 1 |
Cooper, B; Gregerman, RI; Partilla, JS | 1 |
Lad, PM; Lin, MC; Nicosia, S; Rodbell, M | 1 |
Hamet, P; Johnson, RA; Pilkis, SJ | 1 |
Hanoune, J; Mavier, P | 1 |
Hupka, AL; Sweat, FW; Wincek, TJ | 1 |
Bennett, V; Cuatrecasas, P; Jacobs, S | 2 |
Bennett, V; Cuatrecasas, P; Mong, L | 1 |
Helmreich, EJ; Pfeuffer, T; Zenner, HP | 1 |
Poupon, R | 1 |
Johnson, DG; Thompson, WJ; Williams, RH | 1 |
Guellaen, G; Hanoune, J; Lacombe, ML; Rene, E | 1 |
Tomasi, V | 1 |
Lad, PM; Rodbell, M; Welton, AF | 1 |
Lad, PM; Newby, AC; Nicosia, S; Rodbell, M; Welton, AF; Yamamura, H | 1 |
Sweat, FW; Yamashita, L | 2 |
Berman, MF; Lin, MC; Welton, AF | 1 |
Birnbaumer, L; Iyengar, R; Swartz, TL | 1 |
Birnbaumer, L; Iyengar, R | 2 |
Abramowitz, J; Birnbaumer, L; Iyengar, R | 1 |
Doberska, CA; Kennedy, EL; Martin, BR; Metcalfe, JC; Stein, JM | 1 |
Rodbell, M | 4 |
Gregerman, RI; Katz, MS; Kelly, TM; Piñeyro, MA | 1 |
Liang, CT; Sacktor, B; Takenawa, T | 1 |
Magnuson, T; Swislocki, NI; Tierney, J | 1 |
Hanoune, J; Pecker, F | 1 |
Lad, PM; Lin, MC; Londos, C; Rodbell, M; Welton, AF | 1 |
Gregerman, RI; Kalish, MI; Katz, MS; Piñeyro, MA | 1 |
Londos, C; Preston, MS | 2 |
Christophe, J; Dehaye, JP; Winand, J | 1 |
Kimura, N; Nagata, N; Nakane, K | 1 |
Londos, C; Rodbell, M | 1 |
Franks, DJ | 1 |
Criss, WE; Pradhan, TK; Wolff, J | 1 |
Lin, MC; Londos, C; Rendell, M; Rodbell, M; Salomon, Y | 1 |
Hanoune, J; Lacombe, ML; Pecker, F | 1 |
Haley, B; Lin, PC; Shoemaker, M | 1 |
Bataille, D; Capeau, J; Deterre, P; Dufour, M; LeNguyen, D; Lotersztajn, S; Mallat, A; Pavoine, C; Pecker, F; Rouot, B | 1 |
Authier, F; De Galle, B; Desbuquois, B | 1 |
Miyazaki, H; Post, SR; Tager, HS | 1 |
Brechler, V; Fischmeister, R; Garbarz, E; Hanf, R; Pavoine, C; Pecker, F | 1 |
Brighenti, L; Fabbri, E; Ottolenghi, C | 1 |
Akamatu, N; Shima, S | 1 |
Houslay, MD; Milligan, G; Palmer, T; Strassheim, D | 1 |
Houslay, MD; Palmer, TM | 1 |
Bataille, D; Brechler, V; Dufour, M; Le-Nguyen, D; Lotersztajn, S; Pavoine, C; Pecker, F; Roche, B | 1 |
Fernandez-Cruz, A; Fernandez-Durango, R; Sanchez, D | 1 |
Egidy, G; Galvagno, MA; Passeron, S; Paveto, C | 1 |
Das, MR; Hegde, AN | 1 |
Blackmore, PF; Exton, JH; Johnson, EH; Krone, PK; Lynch, CJ; Wange, RL | 1 |
Gurd, RS; McVittie, LD | 1 |
Kimura, N; Shimada, N | 4 |
Donner, DB; Kolhatkar, AA; Lipson, KE; Maki, RG | 1 |
Sheetz, MJ; Tager, HS | 1 |
Attramadal, H; Eikvar, L; Hansson, V | 1 |
García-Sáinz, JA; Hernández-Sotomayor, SM; Macías-Silva, M; Plebañski, M | 1 |
Brighenti, L; Fabbri, E; Gavioli, ME; Ottolenghi, C; Puviani, AC | 1 |
Akamatsu, N; Oikawa, S; Okeyama, N; Shima, S | 1 |
Herberg, JT; Iyengar, R | 2 |
Birnbaumer, L; Rojas, FJ | 1 |
Mason, JC; Tager, HS | 1 |
Martin, BR; Wong, SK | 1 |
Coy, DH; Hruby, VJ; Johnson, DG; McKee, RL; Pelton, JT; Sueiras-Diaz, J; Trivedi, D | 1 |
Bloom, AS; Hillard, CJ; Houslay, MD | 1 |
Donner, DB; Dorato, A; Kolhatkar, AA; Lipson, KE | 1 |
Ho, RJ; Ruiz, J; Shi, QH | 1 |
Floyd, G; Herberg, JT; Iyengar, R; Monsatirsky, B; Padrell, E; Premont, RT | 1 |
Bacchus, RA; Frandsen, EK | 1 |
Bégin-Heick, N; Welsh, J | 1 |
Camus, JC; Chatelain, P; Christophe, J; Robberecht, P; Waelbroeck, M | 1 |
Hansson, V; Jahnsen, T; Smith, AJ | 1 |
Bernstein, KJ; Triner, L; Verosky, M | 1 |
Anand-Srivastava, MB; Srivastava, AK | 1 |
Hodgins, DS; Kuo, JF; Kuo, WN | 1 |
Bitensky, MW; Keirns, JJ; Wheeler, MA | 1 |
Howell, SL; Montague, W | 1 |
Flawiá, MM; Torres, HN | 1 |
Birnbaumer, L; Goldfine, ID; Roth, J | 1 |
Birnbaumer, L; Pohl, SL | 1 |
Rodbell, M; Rubalcava, B | 1 |
Harwood, JP; Löw, H; Rodbell, M | 1 |
Birnbaumer, L | 1 |
Lin, MC; Rodbell, M; Salomon, Y | 1 |
Exton, JH; Johnson, RA; Park, CR; Pilkis, SJ | 1 |
Dalton, C; Hope, H; Sheppard, H | 1 |
Harwood, JP; Lin, MC; Londos, C; Rodbell, M; Salomon, Y; Schramm, M; Wolff, J | 1 |
Sweat, FW; Wincek, TJ | 1 |
Birnbaumer, L; Pohl, SL; Rodbell, M; Sundby, F | 1 |
Chambaut, AM; Hanoune, J; Leray, F | 1 |
Birnbaumer, L; Pohl, SL; Rodbell, M | 1 |
Gurd, RS; Hoosein, NM | 1 |
Hanski, E; Heyworth, CM; Houslay, MD | 1 |
Cooper, ME; Heyworth, CM; Houslay, MD; Payne, NJ; Wallace, AV; Wilson, SR | 1 |
Camus, JC; Chatelain, P; Christophe, J; Gillet, L; Robberecht, P; Waelbroeck, M | 1 |
Houslay, MD; Whetton, AD | 1 |
Abramowitz, J; Birnbaumer, L; Bordelon-Riser, M; Iyengar, R | 1 |
Dipple, I; Elliott, KR; Houslay, MD | 1 |
Amiranoff, B; Laburthe, M; Rosselin, G | 1 |
Houslay, MD | 1 |
Cooper, DM; Kempner, ES; Lad, PM; Londos, C; Nielsen, TB; Preston, MS; Rodbell, M; Schlegel, W | 1 |
Corin, RE; Donner, DB; Ferriola, P | 1 |
Greenberg, ML; Malbon, CC | 1 |
Peters, F; Pingoud, VA | 1 |
Horie, H; Matsuyama, T; Tarui, S | 1 |
Allgayer, H; Bachmann, W; Hepp, KD | 1 |
Martin, BR; Tolkovsky, AM | 1 |
Tkachuk, VA | 1 |
Iynedjian, PB; Salavert, A | 1 |
Birnbaumer, L; Desmier, M; Hanoune, J; Stengel, D | 1 |
Korn, AP; Ottensmeyer, FP | 1 |
Kiss, Z; Tkachuk, VA | 1 |
Birnbaumer, L; Iyengar, R; Mintz, PW; Swartz, TL | 1 |
Johnson, RA | 1 |
Chatelain, P; Christophe, J; De Neef, P; Deschodt-Lanckman, M; König, W; Robberecht, P | 1 |
Martin, BR | 1 |
Breton, M; Colard, O | 1 |
Richards, JM; Swislocki, NI | 1 |
Hynie, S; Klenerová, V | 1 |
Clark, CM; Fricke, RF; Queener, SF | 1 |
Ciani, S; Ribalet, B | 1 |
Houslay, MD; Livingstone, C; MacDonald, C; Willett, B | 1 |
Janssens, PA; Kleineke, JW | 1 |
Caro, JF; Ravindra, R | 1 |
Cortinovis, C; Klimek, F; Nogueira, E | 1 |
Borovok, N; Maltzeva, E; Spassov, V; Zlatanov, I | 1 |
Allende, G; García-Sáinz, JA; Piña, E; Robles-Flores, M | 1 |
Dianzani, MU; Losa, GA; Paradisi, L | 1 |
Cantore, ML; Castilla, R; Passeron, S; Zelada, A | 1 |
Seidler, FJ; Slotkin, TA; Zeiders, JL | 1 |
Beckner, SK | 1 |
Fukuyama, Y; Gotoh, M; Horio, Y; Inanobe, A; Kurachi, Y; Yoshimoto, Y | 1 |
Derkach, KV; Kuznetsova, LA; Pertseva, MN; Plesneva, SA; Shpakov, AO; Uspenskaia, ZI | 1 |
Berggren, PO; Birkenfeld, AL; Cabrera, O; Choi, CS; Kibbey, RG; Lee, HY; Li, C; Pongratz, RL; Shulman, GI; Stanley, C; Zhao, X | 1 |
Jia, G; Sowers, JR | 1 |
Aigner, S; Mutlu, B; Puigserver, P; Sathe, S; Sharabi, K; Tavares, CDJ; Yeo, GW | 1 |
5 review(s) available for glucagon and guanosine triphosphate
Article | Year |
---|---|
Guanyl nucleotide regulation of hormonally-responsive adenylyl cyclases.
Topics: Adenylyl Cyclases; Animals; Binding Sites; Cell Membrane; Cholera Toxin; Enzyme Activation; Erythrocytes; Glucagon; GTP Phosphohydrolases; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Triphosphate; Hormones; Liver; Rats; Receptors, Cell Surface; Turkeys | 1979 |
Hormone-sensitive adenylyl cyclases. Useful models for studying hormone receptor functions in cell-free systems.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Adipose Tissue; Adrenocorticotropic Hormone; Animals; Calcium; Cations, Divalent; Cell Membrane; Cell-Free System; Epinephrine; Fluorides; Glucagon; Guanosine Triphosphate; Kidney Medulla; Kinetics; Liver; Luteinizing Hormone; Models, Biological; Propranolol; Prostaglandins; Receptors, Cell Surface; Secretin; Thyrotropin; Vasopressins | 1973 |
Does insulin exert certain of its actions through a distinct species of guanine nucleotide regulatory protein?
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine Diphosphate Ribose; Adenosine Triphosphate; Adenylyl Cyclases; Animals; Cyclic AMP; Enzyme Activation; Glucagon; GTP-Binding Proteins; Guanosine Triphosphate; Insulin | 1984 |
Nobel Lecture. Signal transduction: evolution of an idea.
Topics: Adenylyl Cyclases; Adipose Tissue; Animals; Cross-Linking Reagents; Detergents; Fluorides; Glucagon; GTP-Binding Proteins; Guanosine Triphosphate; Humans; Liver; Models, Biological; Nobel Prize; Receptors, Cell Surface; Second Messenger Systems; Signal Transduction | 1995 |
Signal transduction: evolution of an idea.
Topics: Adenylyl Cyclases; Animals; Cell Communication; Glucagon; GTP-Binding Proteins; Guanosine Triphosphate; Hormones; Humans; Liver; Receptors, Cell Surface; Second Messenger Systems; Signal Transduction | 1995 |
141 other study(ies) available for glucagon and guanosine triphosphate
Article | Year |
---|---|
Rapid radioimmunoassay for guanosine 3',5'-cyclic monophosphate using tritiated ligand.
Topics: Animals; Binding, Competitive; Cyclic AMP; Cyclic GMP; Glucagon; Guanosine Triphosphate; Humans; Hydrogen-Ion Concentration; Male; Micropore Filters; Phosphoric Diester Hydrolases; Radioimmunoassay; Rats; Salts; Tritium | 1975 |
Human fat cell adenylate cyclase. Enzyme characterization and guanine nucleotide effects on epinephrine responsiveness in cell membranes.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Adipose Tissue; Adrenocorticotropic Hormone; Adult; Cell Membrane; Epinephrine; Female; Fluorides; Glucagon; Guanine Nucleotides; Guanosine Triphosphate; Humans; Hydrogen-Ion Concentration; Magnesium; Male; Temperature | 1976 |
Effects of GTP on binding of (3H) glucagon to receptors in rat hepatic plasma membranes.
Topics: Animals; Binding, Competitive; Cell Membrane; Glucagon; Guanosine Triphosphate; Hydrogen-Ion Concentration; Kinetics; Liver; Rats; Receptors, Cell Surface | 1977 |
Liver membrane adenylate cyclase. Synergistic effects of anions on fluoride, glucagon, and guanyl nucleotide stimulation.
Topics: Adenosine Triphosphatases; Adenylyl Cyclases; Animals; Anions; Azides; Cell Membrane; Cyanides; Enzyme Activation; Fluorides; Glucagon; Guanine Nucleotides; Guanosine Triphosphate; Kinetics; Liver; Rats | 1975 |
Adenylate cyclase from rat-liver plasma membrane: inhibition by mersalyl and other mercurial derivatives.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Adenylyl Cyclase Inhibitors; Animals; Cell Membrane; Chloromercuribenzoates; Dose-Response Relationship, Drug; Enzyme Activation; Female; Fluorides; Glucagon; Guanosine Triphosphate; Kinetics; Liver; Magnesium; Mercaptoethanol; Mercury; Mersalyl; Organomercury Compounds; Organometallic Compounds; Rats | 1975 |
Stimulation of adenylate cyclase from isolated hepatocytes and Kupffer cells.
Topics: Adenylyl Cyclases; Animals; Calcium; Fluorides; Glucagon; Guanosine Triphosphate; Hyaluronoglucosaminidase; In Vitro Techniques; Iron; Isoproterenol; Kupffer Cells; Liver; Male; Microbial Collagenase; Microscopy, Phase-Contrast; Peptides; Perfusion; Prostaglandins E; Rats; Secretin | 1975 |
Irreversible stimulation of adenylate cyclase activity of fat cell membranes of phosphoramidate and phosphonate analogs of GTP.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Adipose Tissue; Adrenocorticotropic Hormone; Aniline Compounds; Animals; Binding, Competitive; Cell Membrane; Diphosphates; Dithiothreitol; Edetic Acid; Fluorides; Glucagon; Guanine Nucleotides; Guanosine Triphosphate; Hydroxylamines; Isoproterenol; Mercury; Organometallic Compounds; Phosphates; Rats; Sodium | 1975 |
Mechanism of activation of adenylate cyclase by Vibrio cholerae enterotoxin. Relations to the mode of activation by hormones.
Topics: Adenylyl Cyclases; Adipose Tissue; Adrenocorticotropic Hormone; Animals; Anti-Bacterial Agents; Enterotoxins; Enzyme Activation; Glucagon; Guanosine Triphosphate; Guinea Pigs; Hormones; Ileum; Intestinal Mucosa; Isoproterenol; Kinetics; Liver; Magnesium; Male; Organ Specificity; Rats; Receptors, Drug; Vibrio cholerae | 1975 |
Signal transfer from hormone receptor to adenylate cyclase.
Topics: Adenylyl Cyclases; Adipose Tissue; Animals; Binding Sites; Calcium; Catecholamines; Cell Membrane; Enzyme Activation; Fluorides; Glucagon; Guanosine Triphosphate; Insulin; Kinetics; Lipids; Liver; Magnesium; Membranes; Myocardium; Protein Binding; Rabbits; Rats; Receptors, Cell Surface | 1976 |
Activity of human adenylate cyclase from human fat cell membranes.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Adipose Tissue; Adrenocorticotropic Hormone; Adult; Aged; Animals; Cell Membrane; Cyclic AMP; Cytosine Nucleotides; Enzyme Activation; Epinephrine; Fluorides; Glucagon; Guanosine Triphosphate; Humans; Middle Aged; Rats | 1975 |
Hormonal regulation of pancreatic islet adenyl cyclase.
Topics: Adenylyl Cyclases; Adrenocorticotropic Hormone; Animals; Cell Membrane; Cholecystokinin; Fluorides; Glucagon; Growth Hormone; Guanosine Triphosphate; Insulin; Islets of Langerhans; Isoproterenol; Kinetics; Male; Phentolamine; Propranolol; Prostaglandins E; Rats; Secretin | 1976 |
Transformation of the beta2 adrenoceptor in normal rat liver into a beta1 type in Zajdela hepatoma.
Topics: Adenylyl Cyclases; Animals; Carcinoma, Hepatocellular; Catecholamines; Enzyme Activation; Epinephrine; Female; Fluorides; Glucagon; Guanosine Triphosphate; Liver; Liver Neoplasms; Neoplasms, Experimental; Rats; Receptors, Adrenergic | 1976 |
Prostaglandin E1 as an intercellular regulator of cyclic AMP levels.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Cyclic AMP; Epinephrine; Fluorides; Glucagon; Guanosine Triphosphate; Inflammation; Liver; Lymphocytes; Phospholipases; Prostaglandins E; Rats; Receptors, Cell Surface; Receptors, Prostaglandin; Trypsin | 1976 |
Evidence for distinct guanine nucleotide sites in the regulation of the glucagon receptor and of adenylate cyclase activity.
Topics: Adenylyl Cyclases; Animals; Bacillus cereus; Cell Membrane; Egtazic Acid; Enzyme Activation; Glucagon; Guanosine Triphosphate; Kinetics; Liver; Phospholipases; Rats; Receptors, Cell Surface | 1977 |
Solubilization and separation of the glucagon receptor and adenylate cyclase in guanine nucleotide-sensitive states.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Enzyme Activation; Glucagon; Guanosine Triphosphate; Liver; Rats; Receptors, Cell Surface; Receptors, Drug; Solubility | 1977 |
Prostaglandin E1 effects on cyclic AMP and glycogen metabolism in rat liver.
Topics: Adenylyl Cyclases; Animals; Cyclic AMP; Glucagon; Glucose; Guanosine Triphosphate; Liver; Liver Glycogen; Male; Prostaglandins E; Rats | 1978 |
Essential role of GTP in the expression of adenylate cyclase activity after cholera toxin treatment.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Cholera Toxin; Enzyme Activation; Fluorides; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Liver; NAD; Peptide Fragments; Rats | 1978 |
Coupling of glucagon receptor to adenylyl cyclase. Requirement of a receptor-related guanyl nucleotide binding site for coupling of receptor to the enzyme.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Liver; Rats; Receptors, Cell Surface | 1979 |
Coupling of the glucagon receptor to adenylyl cyclase by GDP: evidence for two levels of regulation of adenylyl cyclase.
Topics: Adenylyl Cyclases; Animals; Glucagon; GTP Phosphohydrolases; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; In Vitro Techniques; Liver; Rats; Receptors, Cell Surface | 1979 |
Transient complexes. A new structural model for the activation of adenylate cyclase by hormone receptors (guanine nucleotides/irradiation inactivation).
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Enzyme Activation; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hormones; Liver; Macromolecular Substances; Models, Biological; Rats; Receptors, Cell Surface | 1979 |
On the mechanism of activation of fat cell adenylate cyclase by guanine nucleotides. An explanation for the biphasic inhibitory and stimulatory effects of the nucleotides and the role of hormones.
Topics: Adenylyl Cyclases; Adipose Tissue; Adrenocorticotropic Hormone; Animals; Cell Membrane; Enzyme Activation; Epinephrine; Fluorides; Glucagon; Guanine Nucleotides; Guanosine Triphosphate; Hydrogen-Ion Concentration; Kinetics; Magnesium; Rats; Time Factors | 1975 |
Activation of epinephrine and glucagon-sensitive adenylate cyclases of rat liver by cytosol protein factors. Role in loss of enzyme activities during preparation of particulate fractions, quantitation and partial characterization.
Topics: Adenylyl Cyclases; Animals; Cytosol; Enzyme Activation; Epinephrine; Female; Glucagon; Guanosine Triphosphate; Hot Temperature; Liver; Male; Proteins; Rats | 1978 |
Potentiation of GTP of hormone-responsive adenylate cyclase in renal cortex plasma membrane preparations.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Enzyme Activation; Epinephrine; Glucagon; Guanosine Triphosphate; Kidney Cortex; Kidney Tubules, Proximal; Kinetics; Male; Parathyroid Hormone; Prostaglandins E; Rabbits | 1978 |
Properties of rat liver plasma membrane adenylate cyclase after chromatography on O-diethylaminoethyl-cellulose and agarose-hexane-GTP.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Chromatography, Affinity; Glucagon; Guanosine Triphosphate; Hypophysectomy; Kinetics; Liver; Rats; Surface-Active Agents | 1977 |
Activation of epinephrine-sensitive adenylate cyclase in rat liver by cytosolic protein-nucleotide complex.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Cytosol; Enzyme Activation; Epinephrine; Female; Fluorides; Glucagon; Guanosine Triphosphate; Kinetics; Liver; Proteins; Rats | 1977 |
Reversible activation of hepatic adenylate cyclase by guanyl-5'-yl-(alpha,beta-methylene)diphosphonate and guanyl-5'-yl imidodiphosphate.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Diphosphonates; Enzyme Activation; Glucagon; Guanine Nucleotides; Guanosine Triphosphate; Kinetics; Liver; Protein Binding; Rats | 1977 |
Epinephrine-and glucagon-sensitive adenylate cyclases of rat liver during aging. Evidence for membrane instability associated with increased enzymatic activity.
Topics: Adenylyl Cyclases; Aging; Animals; Cell Membrane; Dose-Response Relationship, Drug; Epinephrine; Female; Fluorides; Glucagon; Guanosine Triphosphate; Kinetics; Liver; Male; Rats; Sex Factors | 1977 |
Regulation by glucagon and divalent cations of inhibition of hepatic adenylate cyclase by adenosine.
Topics: Adenosine; Adenosine Triphosphate; Adenylyl Cyclase Inhibitors; Animals; Cell Membrane; Enzyme Activation; Glucagon; Guanosine Triphosphate; Kinetics; Liver; Magnesium; Manganese; Rats | 1977 |
Activation of the hepatic adenylate cyclase system by divalent cations.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Cell Membrane; Enzyme Activation; Glucagon; Guanosine Triphosphate; Kinetics; Liver; Magnesium; Manganese; Rats | 1977 |
Adenylate cyclase activity in hepatic plasma membranes from obese-hyperglycaemic mice [proceedings].
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Enzyme Activation; Fluorides; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hyperglycemia; Liver; Mice; Mice, Obese | 1977 |
The stimulation of rat liver adenylate cyclase by prostaglandins E1 and E2.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Dose-Response Relationship, Drug; Enzyme Activation; Glucagon; Guanosine Triphosphate; Kinetics; Liver; Prostaglandins E; Rats | 1976 |
Activation by GTP of liver adenylate cyclase in the presence of high concentrations of ATP.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Cell Membrane; Enzyme Activation; Fluorides; Glucagon; Guanosine Triphosphate; Kinetics; Liver; Rats | 1976 |
Regulation of hepatic adenylate cyclase by glucagon, GTP, divalent cations, and adenosine.
Topics: Adenosine; Adenylyl Cyclases; Animals; Cations, Divalent; Cell Membrane; Glucagon; Guanosine Triphosphate; Liver; Rats | 1976 |
Cholera toxin and adenylate cyclase: properties of the activated enzyme in liver plasma membranes.
Topics: Adenylyl Cyclases; Animals; Bacterial Toxins; Cell Membrane; Enzyme Activation; Epinephrine; Fluorides; Glucagon; Guanosine Triphosphate; Kinetics; Liver; Magnesium; Male; Mice; Prostaglandins E; Vibrio cholerae | 1976 |
Regulation of adenylate cyclase in two rat liver cell lines, 3C4 and 62.
Topics: Adenylyl Cyclases; Animals; Cell Line; Culture Media; Epinephrine; Fluorides; Glucagon; Guanosine Triphosphate; Kinetics; Prostaglandins A; Prostaglandins E; Rats | 1976 |
Activation of adenylate cyclase by phosphoramidate and phosphonate analogs of GTP: possible role of covalent enzyme-substrate intermediates in the mechanism of hormonal activation.
Topics: Adenylyl Cyclases; Adipose Tissue; Amides; Animals; Chromatography, Affinity; Enzyme Activation; Fluorides; Glucagon; Guanosine Triphosphate; Isoproterenol; Kinetics; Male; Organophosphonates; Rats | 1975 |
The hepatic adenylate cyclase system. I. Evidence for transition states and structural requirements for guanine nucloetide activiation.
Topics: Adenylyl Cyclases; Animals; Binding, Competitive; Cell Membrane; Enzyme Activation; Glucagon; Guanine Nucleotides; Guanosine Triphosphate; Kinetics; Liver; Magnesium; Protein Binding; Rats; Structure-Activity Relationship; Time Factors | 1975 |
The epinephrine-sensitive adenylate cyclase of rat liver plasma membranes. Role of guanyl nucleotides.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Enzyme Activation; Epinephrine; Female; Fluorides; Glucagon; Guanine Nucleotides; Guanosine Triphosphate; Kinetics; Liver; Magnesium; Rats; Structure-Activity Relationship | 1975 |
Identification of the guanine binding domain peptide of the GTP-binding site of glucagon.
Topics: Adenine; Adenine Nucleotides; Adenosine; Amino Acid Sequence; Binding Sites; Binding, Competitive; Chromatography, High Pressure Liquid; Chymotrypsin; Electrophoresis, Polyacrylamide Gel; Glucagon; Guanosine Triphosphate; Humans; Kinetics; Molecular Sequence Data; Peptide Fragments | 1992 |
Role of G protein beta gamma subunits in the regulation of the plasma membrane Ca2+ pump.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Blotting, Western; Ca(2+) Mg(2+)-ATPase; Calcium-Transporting ATPases; Cell Line, Transformed; Cell Membrane; Cells, Cultured; Cholera Toxin; Electrophoresis, Polyacrylamide Gel; Glucagon; GTP-Binding Proteins; Guanosine Triphosphate; Liver; Rats; Sodium Fluoride | 1992 |
Ligand-mediated internalization of glucagon receptors in intact rat liver.
Topics: Adenylyl Cyclases; Amidohydrolases; Animals; Cell Fractionation; Cell Membrane; Cross-Linking Reagents; Dinitrofluorobenzene; Electrophoresis, Polyacrylamide Gel; Glucagon; Golgi Apparatus; Guanosine Triphosphate; Liver; Male; Molecular Weight; Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase; Rats; Rats, Inbred Strains; Receptors, Gastrointestinal Hormone; Receptors, Glucagon | 1992 |
Identification of a Mg(2+)- and guanyl nucleotide-dependent glucagon receptor cycle by use of permeabilized canine hepatocytes.
Topics: Animals; Cell Membrane Permeability; Cells, Cultured; Dogs; Glucagon; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Kinetics; Liver; Magnesium; Models, Biological; Receptors, Gastrointestinal Hormone; Receptors, Glucagon; Saponins; Temperature | 1992 |
Inhibition by glucagon of the cGMP-inhibited low-Km cAMP phosphodiesterase in heart is mediated by a pertussis toxin-sensitive G-protein.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine Triphosphate; Adenylyl Cyclases; Animals; Cyclic AMP; Cyclic GMP; Cytosol; Glucagon; GTP-Binding Proteins; Guanine Nucleotides; Guanosine Triphosphate; Guanylate Cyclase; Heart Ventricles; Intercellular Signaling Peptides and Proteins; Kinetics; Myocardium; Peptides; Pertussis Toxin; Rana esculenta; Virulence Factors, Bordetella; Wasp Venoms | 1992 |
Inhibition of adenylate cyclase of catfish and rat hepatocyte membranes by 9-(tetrahydro-2-furyl)adenine (SQ 22536).
Topics: Adenine; Adenylyl Cyclase Inhibitors; Animals; Cell Membrane; Cells, Cultured; Epinephrine; Female; Glucagon; Guanosine Triphosphate; Ictaluridae; Isoproterenol; Kinetics; Liver; Male; Norepinephrine; Phenylephrine; Rats; Sodium Fluoride; Species Specificity | 1991 |
Multiple controls by adenosine receptors on the adenylate cyclase in the rat hepatic membrane.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Cell Membrane; Cyclic AMP; Glucagon; Guanosine Triphosphate; In Vitro Techniques; Liver; Male; Phenylisopropyladenosine; Rats; Receptors, Purinergic; Sodium Chloride | 1990 |
Alterations in G-protein expression and the hormonal regulation of adenylate cyclase in the adipocytes of obese (fa/fa) Zucker rats.
Topics: Adenylyl Cyclases; Adipose Tissue; Animals; Cell Membrane; Cells, Cultured; Glucagon; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Kinetics; Macromolecular Substances; Male; Obesity; Rats; Rats, Zucker; Secretin; Thyrotropin | 1991 |
Determination of G-protein levels, ADP-ribosylation by cholera and pertussis toxins and the regulation of adenylyl cyclase activity in liver plasma membranes from lean and genetically diabetic (db/db) mice.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Blotting, Western; Cell Membrane; Cholera Toxin; Colforsin; Diabetes Mellitus, Experimental; Glucagon; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Liver; Male; Mice; Mice, Inbred C57BL; Pertussis Toxin; Virulence Factors, Bordetella | 1991 |
Glucagon-(19-29) exerts a biphasic action on the liver plasma membrane Ca2+ pump which is mediated by G proteins.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Calcium; Calcium-Transporting ATPases; Cell Membrane; Cholera Toxin; Female; Glucagon; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Kinetics; Liver; Magnesium; Peptide Fragments; Pertussis Toxin; Rats; Rats, Inbred Strains; Sodium Fluoride; Thionucleotides; Virulence Factors, Bordetella | 1990 |
Identification of glucagon receptors in rat retina.
Topics: Animals; Binding Sites; Binding, Competitive; Glucagon; Guanosine Triphosphate; Kinetics; Osmolar Concentration; Rats; Receptors, Gastrointestinal Hormone; Receptors, Glucagon; Retina | 1990 |
A guanine nucleotide-sensitive, glucagon-stimulated adenylyl cyclase in Candida albicans: effect of glucagon on cell morphology.
Topics: Adenylyl Cyclases; Candida albicans; Enzyme Activation; Glucagon; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Magnesium; Thionucleotides | 1990 |
Glucagon and p21 ras enhance the phosphorylation of the same 38-kilodalton membrane protein from rat liver cells.
Topics: Animals; Electrophoresis, Polyacrylamide Gel; Glucagon; Guanosine Diphosphate; Guanosine Triphosphate; Humans; Kinetics; Liver; Male; Membrane Proteins; Molecular Weight; Oncogene Protein p21(ras); Peptide Mapping; Phosphoproteins; Phosphorylation; Rats; Rats, Inbred Strains; Recombinant Proteins | 1990 |
Guanine nucleotide binding regulatory proteins and adenylate cyclase in livers of streptozotocin- and BB/Wor-diabetic rats. Immunodetection of Gs and Gi with antisera prepared against synthetic peptides.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Aluminum; Angiotensin II; Animals; Catalysis; Cell Line; Cell Membrane; Cholera Toxin; Colforsin; Diabetes Mellitus, Experimental; Enzyme Activation; Fluorine; Glucagon; GTP-Binding Proteins; Guanosine Triphosphate; Immune Sera; Injections, Intraperitoneal; Liver; Male; Peptide Fragments; Pertussis Toxin; Rats; Rats, Inbred BB; Rats, Inbred Strains; Virulence Factors, Bordetella | 1989 |
Stabilization of soluble active rat liver glucagon receptor.
Topics: Animals; Binding, Competitive; Drug Stability; Glucagon; Guanosine Triphosphate; Liver; Male; Rats; Rats, Inbred Strains; Receptors, Gastrointestinal Hormone; Receptors, Glucagon; Salts; Solubility | 1989 |
Direct interaction between membrane-associated nucleoside diphosphate kinase and GTP-binding protein(Gs), and its regulation by hormones and guanine nucleotides.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Glucagon; GTP-Binding Proteins; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Immunoassay; Isoproterenol; Liver; Nucleoside-Diphosphate Kinase; Phosphotransferases; Rats | 1988 |
Divalent cations regulate glucagon binding. Evidence for actions on receptor-Ns complexes and on receptors uncoupled from Ns.
Topics: Animals; Cations, Divalent; Cell Membrane; Edetic Acid; Glucagon; Guanosine Triphosphate; Kinetics; Liver; Magnesium; Male; Rats; Rats, Inbred Strains; Receptors, Gastrointestinal Hormone; Receptors, Glucagon | 1988 |
Receptor-linked proteolysis of membrane-bound glucagon yields a membrane-associated hormone fragment.
Topics: Animals; Chromatography, High Pressure Liquid; Dogs; Electrophoresis, Polyacrylamide Gel; Glucagon; Guanosine Triphosphate; Molecular Weight; Peptide Fragments; Protease Inhibitors; Receptors, Gastrointestinal Hormone; Receptors, Glucagon | 1988 |
Mechanisms of glucagon-induced homologous and heterologous desensitization of adenylate cyclase in membranes and whole Sertoli cells of the rat.
Topics: Adenosine Triphosphate; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Cell Membrane; Cyclic AMP; Drug Tolerance; Follicle Stimulating Hormone; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Male; Pertussis Toxin; Phenylisopropyladenosine; Protein Kinases; Rats; Rats, Inbred Strains; Sertoli Cells; Sodium Fluoride; Virulence Factors, Bordetella | 1988 |
Homologous and heterologous beta-adrenergic desensitization in hepatocytes. Additivity and effect of pertussis toxin.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Drug Interactions; Enzyme Activation; Female; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hypothyroidism; Isoproterenol; Liver; Pertussis Toxin; Propranolol; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Tetradecanoylphorbol Acetate; Urea; Vasopressins; Virulence Factors, Bordetella | 1988 |
Adenylate cyclase of catfish hepatocyte membranes: basal properties and sensitivity to catecholamines and glucagon.
Topics: Adenosine Triphosphate; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Catecholamines; Catfishes; Cell Membrane; Enzyme Activation; Epinephrine; Glucagon; Guanosine Triphosphate; Isoproterenol; Kinetics; Liver; Magnesium; Norepinephrine; Phentolamine; Phenylephrine; Propranolol; Receptors, Adrenergic, beta; Temperature | 1988 |
Effects of chronic propranolol treatment on hepatic adenylate cyclase system in the rat.
Topics: Adenosine Diphosphate; Adenylyl Cyclases; Adrenergic beta-Antagonists; Animals; Blood Glucose; Cell Membrane; Electrophoresis, Polyacrylamide Gel; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Liver; Liver Glycogen; Male; Propanolamines; Propranolol; Rats; Rats, Inbred Strains; Sodium Fluoride | 1987 |
Covalent labeling of the hepatic glucagon receptor.
Topics: Adenylyl Cyclases; Animals; Glucagon; Guanosine Triphosphate; Liver; Membranes; Rats; Receptors, Cell Surface; Receptors, Glucagon | 1985 |
Regulation of glucagon receptor binding. Lack of effect of Mg and preferential role for GDP.
Topics: Adenylyl Cyclases; Animals; Cholera Toxin; Glucagon; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Liver; Magnesium; Rats; Receptors, Cell Surface; Receptors, Glucagon; Thionucleotides | 1985 |
Differential susceptibility to GTP formed from added GDP via membrane-associated nucleoside diphosphate kinase of GTP-sensitive adenylate cyclases achieved by hormone and cholera toxin.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Cholera Toxin; Enzyme Activation; Glucagon; Guanosine Diphosphate; Guanosine Triphosphate; Liver; Male; Nucleoside-Diphosphate Kinase; Phosphotransferases; Rats; Rats, Inbred Strains | 1985 |
Identification of distinct receptor complexes that account for high-and low-affinity glucagon binding to hepatic plasma membranes.
Topics: Animals; Cell Membrane; Chromatography, Affinity; Chromatography, Gel; Dogs; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Liver; Receptors, Cell Surface; Receptors, Glucagon | 1985 |
GTP-activated GTP binding protein(Gs) in membranes achieved by hormone plus GDP does not serve as a substrate for ADP-ribosylation by cholera toxin.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Cholera Toxin; Enzyme Activation; Glucagon; GTP-Binding Proteins; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Triphosphate; Molecular Weight; Nucleoside Diphosphate Sugars; Rats; Receptors, Cell Surface; Receptors, Glucagon | 1986 |
Activation of rat liver adenylate cyclase by guanosine 5'-[beta,gamma-imido]triphosphate and glucagon. Existence of reversibly and irreversibly activated states of the stimulatory GTP-binding protein.
Topics: Adenylyl Cyclases; Animals; Cyclic AMP; Enzyme Activation; Glucagon; GTP-Binding Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Liver; Rats; Thionucleotides | 1986 |
Receptor binding and adenylate cyclase activities of glucagon analogues modified in the N-terminal region.
Topics: Adenylyl Cyclases; Animals; Binding, Competitive; Cell Membrane; Glucagon; Guanosine Triphosphate; Iodine Radioisotopes; Kinetics; Liver; Male; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Glucagon; Structure-Activity Relationship | 1986 |
Effects of delta 9-tetrahydrocannabinol on glucagon receptor coupling to adenylate cyclase in rat liver plasma membranes.
Topics: Adenylyl Cyclases; Animals; Cannabinoids; Cell Membrane; Colforsin; Dronabinol; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Liver; Male; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Glucagon; Sodium Fluoride | 1986 |
N-ethylmaleimide uncouples the glucagon receptor from the regulatory component of adenylyl cyclase.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Ethylmaleimide; Glucagon; GTP-Binding Proteins; Guanosine Triphosphate; Kinetics; Liver; Male; Rats; Rats, Inbred Strains; Receptors, Gastrointestinal Hormone; Receptors, Glucagon | 1986 |
A dose-response study of forskolin, stimulatory hormone, and guanosine triphosphate analog on adenylate cyclase from several sources.
Topics: Adenylyl Cyclases; Adipose Tissue; Adrenocorticotropic Hormone; Animals; Cell Membrane; Colforsin; Drug Synergism; Enzyme Activation; Epinephrine; Erythrocyte Membrane; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hormones; Liver; Rabbits; Rats; Solubility | 1986 |
The hepatic glucagon receptor: a comparative study of the regulatory and structural properties.
Topics: Adenylate Cyclase Toxin; Animals; Biological Assay; Cell Membrane; Chickens; Cross-Linking Reagents; Glucagon; GTP-Binding Proteins; Guanosine Triphosphate; Liver; Magnesium; Magnesium Chloride; Molecular Weight; Rabbits; Rats; Receptors, Gastrointestinal Hormone; Receptors, Glucagon; Species Specificity; Virulence Factors, Bordetella | 1987 |
Glucagon receptor binding, dissociation and degradation in rat liver plasma membranes studied by a microperifusion method.
Topics: Animals; Cell Membrane; Glucagon; Guanosine Triphosphate; Kinetics; Liver; Peptide Hydrolases; Protein Binding; Rats; Rats, Inbred Strains; Receptors, Gastrointestinal Hormone; Receptors, Glucagon | 1987 |
The regulation of adenylate cyclase in liver membranes of lean and obese mice.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Cell Membrane; Cholera Toxin; Enzyme Activation; Glucagon; Guanosine Triphosphate; Isoproterenol; Liver; Magnesium; Magnesium Chloride; Male; Mice; Mice, Inbred C57BL; Norepinephrine; Obesity; Pertussis Toxin; Propranolol; Virulence Factors, Bordetella; Yohimbine | 1988 |
Modulation by n-alkanols of rat cardiac adenylate cyclase activity.
Topics: Adenylyl Cyclases; Alcohols; Animals; Cell Membrane; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Myocardium; Rats; Secretin; Sodium Fluoride; Structure-Activity Relationship | 1986 |
Membrane-bound adenylate cyclase activity in the testis of the blue fox.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Chorionic Gonadotropin; Dose-Response Relationship, Drug; Follicle Stimulating Hormone; Foxes; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Magnesium; Male; Manganese; Membranes; Testis; Time Factors | 1985 |
Effect of halothane on rat liver adenylate cyclase: role of cytosol components.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Cell Membrane; Cytosol; Enzyme Activation; Glucagon; Guanosine Triphosphate; Halothane; Hot Temperature; In Vitro Techniques; Liver; Male; Protein Denaturation; Rats; Rats, Inbred Strains; Serum Albumin, Bovine; Trypsin | 1985 |
Streptozotocin-induced diabetes and hormone sensitivity of adenylate cyclase in rat myocardial sarcolemma, aorta and liver.
Topics: Adenylyl Cyclases; Animals; Aorta; Catecholamines; Colforsin; Corpus Striatum; Diabetes Mellitus, Experimental; Diterpenes; Glucagon; Guanosine Triphosphate; Hormones; Liver; Male; Myocardium; Rats; Rats, Inbred Strains; Sarcolemma | 1985 |
Regulation by various hormones and agents of adenosine-3',5'-monophosphate levels in islets of Langerhans of rats.
Topics: Adenine; Adrenergic beta-Antagonists; Adrenocorticotropic Hormone; Animals; Cresols; Cyclic AMP; Epinephrine; Glucagon; Glucose; Guanosine Triphosphate; Hormones; In Vitro Techniques; Islets of Langerhans; Isoproterenol; Leucine; Phenformin; Phenoxybenzamine; Phentolamine; Propanolamines; Propranolol; Propylamines; Prostaglandins; Rats; Receptors, Adrenergic; Secretin; Sotalol; Theophylline; Thyrotropin; Tolbutamide; Tritium | 1974 |
Isolation of cyclic AMP and cyclic GMP by thin-layer chromatography. Application to assay of adenylate cyclase, guanylate cyclase, and cyclic nucleotide phosphodiesterase.
Topics: Adenine; Adenosine Triphosphate; Adenylyl Cyclases; Alloxan; Animals; Anura; Carbon Radioisotopes; Cell Membrane; Chromatography, Ion Exchange; Chromatography, Thin Layer; Cyclic AMP; Cyclic GMP; Evaluation Studies as Topic; Glucagon; Guanine; Guanosine Triphosphate; Guanylate Cyclase; Kinetics; Liver; Lung; Methods; Phosphoric Diester Hydrolases; Photoreceptor Cells; Rats; Time Factors; Tritium | 1974 |
Adenylate cyclase activity in isolated rat islets of Langerhans. Effects of agents which alter rates of insulin secretion.
Topics: Adenylyl Cyclases; Animals; Arginine; Epinephrine; Fluorides; Glucagon; Glucose; Glyburide; Guanosine Triphosphate; Hydrogen-Ion Concentration; In Vitro Techniques; Islets of Langerhans; Isoproterenol; Kinetics; Leucine; Male; Norepinephrine; Nucleotides; Phenoxybenzamine; Phosphorus Radioisotopes; Potassium; Propranolol; Prostaglandins; Rats; Xylitol | 1973 |
Activation of membrane-bound adenylate cyclase by glucagon in Neurospora crassa.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Carbon Isotopes; Cell Membrane; Detergents; Drug Interactions; Enzyme Activation; Glucagon; Glycogen Synthase; Guanosine Triphosphate; Kinetics; Manganese; Neurospora; Neurospora crassa; Osmolar Concentration; Phosphorus Isotopes; Phosphorylases; Protein Binding; Stimulation, Chemical | 1972 |
Glucagon receptors in -cells. Binding of 125 I-glucagon and activation of adenylate cyclase.
Topics: Adenoma, Islet Cell; Adenosine Monophosphate; Adenosine Triphosphate; Adenylyl Cyclases; Animals; Antigens; Binding Sites; Cricetinae; Enzyme Activation; Glucagon; Guanosine Triphosphate; Immune Sera; Intestines; Iodine Isotopes; Pancreas; Phosphorus Isotopes; Protein Binding; Receptors, Drug; Subcellular Fractions; Swine; Time Factors; Tritium | 1972 |
Relation of glucagon-specific binding sites to glucagon-dependent stimulation of adenylyl cyclase activity in plasma membranes of rat liver.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Binding Sites; Cell Membrane; Cyclic AMP; Glucagon; Guanosine Triphosphate; Histidine; Iodine Isotopes; Kinetics; Liver; Phosphorus Isotopes; Purine Nucleotides; Rats; Receptors, Cell Surface; Receptors, Drug; Time Factors; Tritium | 1973 |
The role of acidic phospholipids in glucagon action on rat liver adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Bacillus cereus; Binding Sites; Binding, Competitive; Cell Membrane; Clostridium perfringens; Enzyme Activation; Glucagon; Guanosine Triphosphate; Histidine; Hydrogen-Ion Concentration; Iodine Isotopes; Liver; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipases; Phospholipids; Protein Binding; Rats; Sphingomyelins; Structure-Activity Relationship | 1973 |
The problem of identifying the glucagon receptor.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Binding Sites; Cell Membrane; Cyclic AMP; Enzyme Activation; Fluorides; Glucagon; Guanosine Triphosphate; Kinetics; Liver; Models, Biological; Rats; Receptors, Cell Surface | 1973 |
Stimulatory and inhibitory effects of guanyl nucleotides on fat cell adenylate cyclase.
Topics: Adenosine Triphosphate; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adipose Tissue; Adrenocorticotropic Hormone; Animals; Catalysis; Cell Membrane; Centrifugation, Density Gradient; Cyclic AMP; Enzyme Activation; Epididymis; Epinephrine; Glucagon; Guanine Nucleotides; Guanosine Triphosphate; Inosine Nucleotides; Male; Rats; Structure-Activity Relationship; Uracil Nucleotides | 1973 |
Evidence for interdependent action of glucagon and nucleotides on the hepatic adenylate cyclase system.
Topics: Adenine Nucleotides; Adenylyl Cyclases; Animals; Binding Sites; Cell Membrane; Chromatography, Ion Exchange; Cyclic AMP; Glucagon; Guanosine Triphosphate; Iodine Radioisotopes; Kinetics; Liver; Phosphorus Radioisotopes; Protein Binding; Rats; Receptors, Cell Surface; Time Factors | 1974 |
Effects of glucagon on cyclic AMP and carbohydrate metabolism in livers from diabetic rats.
Topics: Adenylyl Cyclases; Animals; Calcium; Carbohydrate Metabolism; Cell Membrane; Cyclic AMP; Diabetes Mellitus; Diabetes Mellitus, Experimental; Glucagon; Guanosine Triphosphate; Kinetics; Liver; Magnesium; Male; Ouabain; Phosphoric Diester Hydrolases; Rats; Streptozocin; Theophylline | 1974 |
Regulation of hormone stimulation of adipose tissue lipolysis by guanosine triphosphate.
Topics: Adenosine Triphosphate; Adipose Tissue; Adrenocorticotropic Hormone; Animals; Cyclic AMP; Cyclic GMP; Cytosine Nucleotides; Epididymis; Fatty Acids, Nonesterified; Glucagon; Guanine Nucleotides; Guanosine Triphosphate; Inosine Nucleotides; Kinetics; Lipid Mobilization; Male; Norepinephrine; Prostaglandins; Rats; Spectrometry, Fluorescence; Theophylline; Thymine Nucleotides; Time Factors; Uracil Nucleotides | 1974 |
5'-Guanylylimidodiphosphate, a potent activator of adenylate cyclase systems in eukaryotic cells.
Topics: Adenylyl Cyclases; Adipose Tissue; Adrenal Gland Neoplasms; Adrenal Glands; Allosteric Regulation; Animals; Anura; Cattle; Cell Line; Cell Membrane; Enzyme Activation; Epinephrine; Erythrocytes; Escherichia coli; Fluorides; Glucagon; Guanine Nucleotides; Guanosine Triphosphate; Liver; Propranolol; Rats; Salmon; Stimulation, Chemical; Thyroid Gland | 1974 |
The stimulation of hepatic adenylate cyclase by prostaglandin E1.
Topics: Adenylyl Cyclases; Aluminum; Animals; Chromatography; Chromatography, Ion Exchange; Dogs; Enzyme Activation; Fluorides; Glucagon; Guanosine Triphosphate; Kinetics; Liver; Mice; Phosphorus Radioisotopes; Prostaglandins; Rabbits; Rats; Species Specificity | 1973 |
The glucagon-sensitive adenylate cyclase system in plasma membranes of rat liver. VII. Hormonal stimulation: reversibility and dependence on concentration of free hormone.
Topics: Adenosine Triphosphate; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Allosteric Regulation; Animals; Binding Sites; Cell Membrane; Drug Synergism; Fluorides; Glucagon; Guanosine Triphosphate; Histidine; Iodine Isotopes; Liver; Osmolar Concentration; Phosphorus Isotopes; Rats; Structure-Activity Relationship; Time Factors | 1972 |
Role of GTP in epinephrine and glucagon activation of adenyl cyclase of liver plasma membrane.
Topics: Adenylyl Cyclases; Adrenal Glands; Animals; Cell Membrane; Enzyme Activation; Epinephrine; Female; Fluorides; Glucagon; Guanosine Triphosphate; In Vitro Techniques; Liver; Phosphorus Isotopes; Rats; Tritium | 1972 |
Characteristics of glucagon action on the hepatic adenylate cyclase system.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Binding Sites; Enzyme Activation; Glucagon; Guanosine Triphosphate; Liver; Models, Chemical; Phospholipids; Rats; Structure-Activity Relationship | 1971 |
Identification of glucagon receptors in rat brain.
Topics: Adenylyl Cyclases; Animals; Binding Sites; Brain; Enzyme Activation; Glucagon; Guanosine Triphosphate; Insulin; Liver; Male; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Glucagon; Subcellular Fractions; Tissue Distribution | 1984 |
Islet-activating protein blocks glucagon desensitization in intact hepatocytes.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Animals; Bacterial Proteins; Bacterial Toxins; Cell Membrane; Cyclic AMP; Glucagon; Guanosine Triphosphate; In Vitro Techniques; Liver; Male; Pertussis Toxin; Rats; Rats, Inbred Strains; Virulence Factors, Bordetella | 1984 |
Glucagon-stimulated GTP hydrolysis in rat liver plasma membranes.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Dose-Response Relationship, Drug; Glucagon; GTP Phosphohydrolases; Guanosine Triphosphate; Kinetics; Liver; Phosphoric Monoester Hydrolases; Rats | 1980 |
Selective alteration of secretin-stimulated cardiac adenylate cyclase activity in streptozotocin-diabetic rats.
Topics: Adenylyl Cyclases; Animals; Diabetes Mellitus, Experimental; Glucagon; Guanosine Triphosphate; Isoproterenol; Male; Myocardium; Rats; Rats, Inbred Strains; Secretin; Sodium Fluoride; Streptozocin | 1983 |
The effect of vinblastine on the glucagon, basal and GTP-stimulated states of the adenylate cyclase from rat liver plasma membranes.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Dose-Response Relationship, Drug; Glucagon; Guanosine Triphosphate; Liver; Male; Rats; Receptors, Cell Surface; Vinblastine | 1980 |
Hormone receptor-mediated stimulation of adenylyl cyclase systems. Nucleotide effects and analysis in terms of a simple two-state model for the basic receptor-affected enzyme.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Enzyme Activation; Epoprostenol; Glucagon; Guanine Nucleotides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Liver; Rats; Receptors, Cell Surface | 1980 |
Guanosine 5'-triphosphate and guanosine 5'-[beta gamma-imido]triphosphate effect a collision coupling mechanism between the glucagon receptor and catalytic unit of adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Benzyl Alcohols; Cell Membrane; Cricetinae; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; In Vitro Techniques; Kinetics; Ligands; Liver; Male; Rats; Receptors, Cell Surface; Sodium Chloride; Trypsin | 1980 |
Differential effects of guanine nucleotides on the first step of VIP and glucagon action in membranes from liver cells.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Gastrointestinal Hormones; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Liver; Rats; Receptors, Cell Surface; Vasoactive Intestinal Peptide | 1980 |
Mobile receptor and collision coupling mechanisms for the activation of adenylate cyclase by glucagon.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Enzyme Activation; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Lipid Bilayers; Liver; Rats; Receptors, Cell Surface; Receptors, Glucagon; Trypsin | 1981 |
The structure of adenylate cyclase systems.
Topics: Adenylyl Cyclases; Adipose Tissue; Animals; Cell Membrane; Erythrocytes; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Liver; Macromolecular Substances; Molecular Weight; Rats; Receptors, Cell Surface; Turkeys | 1981 |
Hepatic glucagon-receptor complexes lose sensitivity to the dissociating effect of GTP.
Topics: Animals; Cell Membrane; Glucagon; Guanosine Triphosphate; Kinetics; Liver; Male; Protein Binding; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Glucagon | 1982 |
3,3',5-triiodothyronine administration in vivo modulates the hormone-sensitive adenylate cyclase system of rat hepatocytes.
Topics: Adenylyl Cyclases; Animals; Benzyl Alcohols; Cholera Toxin; Cyclic AMP; Epinephrine; Female; Glucagon; Guanosine Triphosphate; Hormones; Hyperthyroidism; Isoproterenol; Liver; Pindolol; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Triiodothyronine; Triiodothyronine, Reverse | 1982 |
A critical interpretation of experiments on binding of peptide hormone to specific receptors by computer modelling.
Topics: Animals; Computers; Glucagon; Guanosine Triphosphate; Insulin; Liver; Models, Biological; Receptor, Insulin; Receptors, Cell Surface; Receptors, Glucagon | 1982 |
[Recent findings on glucagon receptors and isolation of glicentin].
Topics: Animals; Glucagon; Guanosine Triphosphate; Proglucagon; Protein Precursors; Receptors, Cell Surface; Receptors, Glucagon | 1981 |
Increased dose-response relationship of liver plasma membrane adenylate cyclase to glucagon stimulation in diabetic rats. A possible role of the guanyl nucleotide-binding regulatory protein.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Glucagon; GTP-Binding Proteins; Guanosine Triphosphate; Insulin; Liver; Male; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Sodium Fluoride; Streptozocin | 1982 |
Hormone receptor modulates the regulatory component of adenylyl cyclase by reducing its requirement for Mg2+ and enhancing its extent of activation by guanine nucleotides.
Topics: Adenylyl Cyclases; Animals; Cell Line; Cell Membrane; Ethylmaleimide; Glucagon; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Kinetics; Liver; Lymphoma; Magnesium; Mice; Neoplasms, Experimental; Receptors, Cell Surface; Receptors, Glucagon; Thionucleotides | 1982 |
The glucagon receptor from liver can be functionally fused to caudate nucleus adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Caudate Nucleus; Cell Membrane; Enzyme Activation; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Liver; Rats; Receptors, Cell Surface; Receptors, Glucagon | 1982 |
Regulation of adenylate cyclase by hormones and guanine nucleotides in normal, desensitized, and resensitized rabbit heart.
Topics: Adenylyl Cyclases; Animals; Catecholamines; Dose-Response Relationship, Drug; Enzyme Activation; Epinephrine; Female; Glucagon; Guanine Nucleotides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Histamine; Isoproterenol; Male; Myocardium; Rabbits; Receptors, Adrenergic, beta; Sarcolemma | 1982 |
Structural analysis of the hepatic glucagon receptor. Identification of a guanine nucleotide-sensitive hormone-binding region.
Topics: Acetylglucosaminidase; Animals; Cell Membrane; Glucagon; Guanosine Triphosphate; Kinetics; Liver; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Molecular Weight; Rats; Receptors, Cell Surface; Receptors, Glucagon | 1984 |
Effects of glucagon, dexamethasone and triiodothyronine on phosphoenolpyruvate carboxykinase (GTP) synthesis and mRNA level in rat liver cells.
Topics: Animals; Cell-Free System; Cytosol; Dexamethasone; Electrophoresis; Glucagon; Guanosine Triphosphate; In Vitro Techniques; Liver; Male; Phosphoenolpyruvate Carboxykinase (GTP); Protein Biosynthesis; Rats; Rats, Inbred Strains; RNA, Messenger; Time Factors; Triiodothyronine | 1984 |
Forskolin regulation of liver membrane adenylyl cyclase.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Cell Membrane; Chemical Phenomena; Chemistry; Colforsin; Diterpenes; Enzyme Activation; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Liver; Rats; Sodium Fluoride | 1983 |
A model for the three-dimensional structure of glucagon.
Topics: Glucagon; Guanosine Triphosphate; Hydrogen Bonding; Models, Molecular; Molecular Conformation | 1983 |
Guanine-nucleotide-dependent inhibition of adenylate cyclase of rabbit heart by glucagon.
Topics: Adenylyl Cyclase Inhibitors; Animals; Benzyl Alcohol; Benzyl Alcohols; Enzyme Activation; Ethanol; Female; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Male; Myocardium; Rabbits; Rats; Rats, Inbred Strains | 1984 |
Divalent cation-induced desensitization of glucagon-stimulable adenylyl cyclase in rat liver plasma membrane. GTP-dependent stimulation by glucagon.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Cations, Divalent; Cell Membrane; Edetic Acid; Enzyme Activation; Glucagon; Guanosine Triphosphate; Kinetics; Liver; Rats | 1980 |
Changes in pH sensitivity of adenylate cyclase specifically induced by fluoride and vanadate.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Enzyme Activation; Fluorides; Glucagon; Guanosine Triphosphate; Hydrogen-Ion Concentration; Liver; Magnesium; Manganese; Rats; Sodium Fluoride; Vanadates; Vanadium | 1982 |
Secretin and VIP-stimulated adenylate cyclase from rat heart. I. General properties and structural requirements for enzyme activation.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Dose-Response Relationship, Drug; Enzyme Activation; Gastrointestinal Hormones; Glucagon; Guanosine Triphosphate; In Vitro Techniques; Isoproterenol; Magnesium; Male; Myocardium; Rats; Secretin; Structure-Activity Relationship; Vasoactive Intestinal Peptide | 1980 |
Transient receptor coupling in the activation of rat liver plasma-membrane adenylate cyclase by glucagon.
Topics: Adenylyl Cyclases; Animals; Binding Sites; Cell Membrane; Enzyme Activation; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Liver; Rats | 1981 |
Rat liver plasma membrane phospholipids methylation; its absence of direct relationship to adenylate cyclase activities.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Glucagon; Guanosine Triphosphate; In Vitro Techniques; Liver; Membrane Lipids; Methylation; Methyltransferases; Phosphatidylethanolamine N-Methyltransferase; Phospholipids; Rats; Sodium Fluoride | 1981 |
Mechanism of molybdate activation of adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Enzyme Activation; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hydrogen-Ion Concentration; Kinetics; Liver; Molybdenum; Rats; Sodium Fluoride | 1981 |
Effects of dimethyl sulfoxide and other dipolar aprotic solvents on rat hepatic adenylate cyclase. Potentiating effects on glucagon and guanylylimidodiphosphate stimulation.
Topics: Adenylyl Cyclases; Animals; Dimethyl Sulfoxide; Drug Synergism; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Liver; Rats; Solvents; Stimulation, Chemical; Time Factors | 1980 |
Cardiac adenylate cyclase: kinetics of synergistic activation by guanosine-5'-triphosphate (GTP) and glucagon.
Topics: Adenylyl Cyclases; Animals; Drug Synergism; Enzyme Activation; Glucagon; Guanosine Triphosphate; Kinetics; Male; Myocardium; Rats | 1980 |
Characterization of the G protein coupling of a glucagon receptor to the KATP channel in insulin-secreting cells.
Topics: Adenosine Triphosphate; Animals; Cholera Toxin; Cricetinae; Electrophysiology; Glucagon; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Magnesium; Membrane Potentials; Patch-Clamp Techniques; Potassium Channels; Rats; Receptors, Glucagon; Tumor Cells, Cultured | 1994 |
Analysis of the adenylate cyclase signalling system, and alterations induced by culture with insulin, in a novel SV40-DNA-immortalized hepatocyte cell line (P9 cells).
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Alprostadil; Animals; Cell Line; Cell Transformation, Viral; Colforsin; Glucagon; GTP-Binding Proteins; Guanosine Triphosphate; Insulin; Liver; Male; Rats; Rats, Sprague-Dawley; Receptor, Insulin; Signal Transduction | 1994 |
Hormone-induced rise in cytosolic Ca2+ in axolotl hepatocytes: extracellular origin and control by cAMP.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Ambystoma mexicanum; Animals; Calcium; Cells, Cultured; Cyclic AMP; Cytosol; Epinephrine; Glucagon; Guanosine Triphosphate; Inositol 1,4,5-Trisphosphate; Isoproterenol; Kinetics; Liver; Phentolamine; Propranolol; Thionucleotides; Vasotocin | 1993 |
Insulin stimulates GDP release from G proteins in the rat and human liver plasma membranes.
Topics: Adult; Animals; Cell Membrane; Glucagon; GTP-Binding Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Humans; Insulin; Liver; Male; Rats; Rats, Sprague-Dawley | 1993 |
Adenylate cyclase activity in microdissected rat liver tissue: periportal to pericentral activity gradient.
Topics: Adenylyl Cyclases; Angiotensin II; Animals; Chlorides; Cholera Toxin; Colforsin; Cyclic AMP; Glucagon; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Lithium; Lithium Chloride; Liver; Male; Rats; Rats, Sprague-Dawley; Sodium Fluoride | 1993 |
Effect of insulin and glucagon on the mobility of ESR-probes incorporated in rat liver plasma membranes.
Topics: Adenylyl Cyclases; Animals; Butylated Hydroxytoluene; Caprylates; Cell Membrane; Cyclic N-Oxides; Dinoprostone; Electron Spin Resonance Spectroscopy; Enzyme Activation; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Insulin; Kinetics; Liver; Membrane Fluidity; Rats; Rats, Wistar; Spin Labels | 1993 |
Cross-talk between glucagon- and adenosine-mediated signalling systems in rat hepatocytes: effects on cyclic AMP-phosphodiesterase activity.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylate Cyclase Toxin; Animals; Cell Membrane; Glucagon; Guanosine Triphosphate; Liver; Male; Pertussis Toxin; Phenylisopropyladenosine; Rats; Rats, Wistar; Receptors, Purinergic P1; Signal Transduction; Virulence Factors, Bordetella | 1995 |
Enzymatic, biophysical and ultrastructural changes of plasma membranes in chemical-induced rat hepatoma.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Freeze Fracturing; Glucagon; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Lipid Metabolism; Liver Neoplasms, Experimental; Male; Membrane Proteins; Methyltransferases; Rats; Rats, Inbred F344; Spin Labels | 1995 |
Reassessment of the effect of glucagon and nucleotides on Candida albicans germ tube formation.
Topics: Acetylglucosamine; Candida albicans; Cyclic AMP; Glucagon; Guanosine Triphosphate | 1996 |
Ontogeny of regulatory mechanisms for beta-adrenoceptor control of rat cardiac adenylyl cyclase: targeting of G-proteins and the cyclase catalytic subunit.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Age Factors; Animals; Animals, Newborn; Body Weight; Carbachol; Cell Membrane; Colforsin; Drug Hypersensitivity; Female; Glucagon; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; GTP-Binding Proteins; Guanosine Triphosphate; Heart; Isoproterenol; Male; Manganese; Membrane Proteins; Muscarinic Agonists; Myocardium; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Time Factors | 1997 |
G-protein activation by chemokines.
Topics: Animals; Bacterial Toxins; Chemokines; Epinephrine; Glucagon; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine Triphosphate; Interleukin-2; Lymphocytes; Membrane Proteins; Protein Binding; Receptors, Chemokine; Signal Transduction | 1997 |
Somatostatin induces hyperpolarization in pancreatic islet alpha cells by activating a G protein-gated K+ channel.
Topics: Acetylcholine; Animals; Electrophysiology; Female; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Glucagon; GTP-Binding Proteins; Guanosine Triphosphate; Immunohistochemistry; Ion Channel Gating; Islets of Langerhans; Mice; Mice, Inbred Strains; Patch-Clamp Techniques; Pertussis Toxin; Potassium Channels; Potassium Channels, Inwardly Rectifying; RNA, Messenger; Somatostatin; Tolbutamide; Virulence Factors, Bordetella | 1999 |
[The hormone-sensitive adenylyl cyclase system of the ciliate Dileptus anser].
Topics: Adenylyl Cyclases; Animals; Ciliophora; Enzyme Activation; Epinephrine; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Protein Synthesis Inhibitors; Serotonin; Structure-Activity Relationship | 2002 |
Mitochondrial GTP insensitivity contributes to hypoglycemia in hyperinsulinemia hyperammonemia by inhibiting glucagon release.
Topics: Amino Acids; Animals; Glucagon; Glucagon-Secreting Cells; Glucose Clamp Technique; Glutamate Dehydrogenase; Guanosine Triphosphate; Humans; Hyperammonemia; Hyperinsulinism; Hypoglycemia; Insulin; Insulin Secretion; Insulin-Secreting Cells; Mice; Mice, Transgenic; Mitochondria; Mutation; Syndrome | 2014 |
Interaction of islet α-cell and β-cell in the regulation of glucose homeostasis in HI/HA syndrome patients with the GDH(H454Y) mutation.
Topics: Amino Acids; Animals; Glucagon; Glucagon-Secreting Cells; Glutamate Dehydrogenase; Guanosine Triphosphate; Humans; Hyperammonemia; Hyperinsulinism; Hypoglycemia; Insulin; Insulin Secretion; Insulin-Secreting Cells; Mitochondria | 2014 |
Transcriptome-wide analysis of PGC-1α-binding RNAs identifies genes linked to glucagon metabolic action.
Topics: Adenosine Triphosphate; Animals; Calcium-Binding Proteins; Cells, Cultured; Gene Expression Profiling; Gene Expression Regulation; Glucagon; Gluconeogenesis; Glucose; Guanosine Triphosphate; Hepatocytes; Liver; Male; Metabolomics; Mice; Mice, Inbred C57BL; Mitochondrial Membrane Transport Proteins; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Protein Binding; Transcriptome | 2020 |