glucagon has been researched along with glyburide in 116 studies
| Studies (glucagon) | Trials (glucagon) | Recent Studies (post-2010) (glucagon) | Studies (glyburide) | Trials (glyburide) | Recent Studies (post-2010) (glyburide) |
|---|---|---|---|---|---|
| 26,039 | 1,498 | 3,054 | 6,554 | 620 | 1,344 |
| Protein | Taxonomy | glucagon (IC50) | glyburide (IC50) |
|---|---|---|---|
| ATP-binding cassette sub-family C member 9 | Homo sapiens (human) | 0.22 | |
| Bile salt export pump | Rattus norvegicus (Norway rat) | 5.7 | |
| Bile salt export pump | Homo sapiens (human) | 5.5333 | |
| Cytochrome P450 2C9 | Homo sapiens (human) | 1.602 | |
| ATP-binding cassette sub-family C member 8 | Homo sapiens (human) | 0.0043 | |
| ATP-sensitive inward rectifier potassium channel 11 | Homo sapiens (human) | 0.1121 | |
| NACHT, LRR and PYD domains-containing protein 3 | Mus musculus (house mouse) | 10 | |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | 1.8 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 56 (48.28) | 18.7374 |
| 1990's | 34 (29.31) | 18.2507 |
| 2000's | 18 (15.52) | 29.6817 |
| 2010's | 6 (5.17) | 24.3611 |
| 2020's | 2 (1.72) | 2.80 |
| Authors | Studies |
|---|---|
| Callaghan, S; Grant, AP; Hayes, JR | 1 |
| Efendić, S; Enzmann, F; Luft, R; Nylén, A; Uvnäs-Wallensten, K | 2 |
| Coetzee, EJ; Jackson, WP | 1 |
| Blayac, JP; Chapal, J; Loubatières, AL; Loubatières-Mariani, MM | 1 |
| Macchi, IA; Zeytinoğlu, FN | 1 |
| Campillo, JE; de los Arcos, JG; Marasco, M; Melani, F; Osorio, J; Pagés, I; Rodríguez, E | 1 |
| Aparicio, N; Basabe, JC; Cresto, JC | 1 |
| Cerasi, E; Grill, V | 1 |
| Carpentier, JL; Malaisse-Lagae, F; Müller, WA | 1 |
| Andreani, D; Fallucca, F; Iavicoli, M; Menzinger, G; Mirabella, C | 1 |
| Baumeister, G; Stahl, M; Wagner, H | 1 |
| Baumeister, G; Stahl, M; Wagner, H; Zierden, E | 1 |
| Ambrosi, F; Cristallini, S; Filipponi, P; Gregorio, F; Pedetti, M; Santeusanio, F | 1 |
| Atiea, JA; Luzio, S; Owens, DR | 1 |
| Birkeland, KI; Chatzipanagiotou, F; Hanssen, KF; Vaaler, S | 1 |
| Bierman, EL; Childs, MT; Ensinck, JW; Friday, KE; Fujimoto, WY; Zambon, S | 1 |
| Aoki, M; Inoue, H; Kaku, K; Kaneko, T; Matsuda, M | 1 |
| Cooper, GJ; Moore, CX | 1 |
| Ahrén, B; Efendic, S; Karlsson, S; Ostenson, CG; Sandberg, E | 1 |
| Go, VL; Opara, EC | 1 |
| Akkan, AG; Ledercq-Meyer, V; Malaisse, WJ; Marchand, J | 1 |
| Fujiyama, K; Hoshino, T; Ikeda, T; Mashiba, H; Takeuchi, T; Tominaga, M | 1 |
| Reckless, JP; Simpson, HC; Stirling, CA; Sturley, R | 1 |
| Fujita, Y; Kawaji, K; Kubo, H; Shirataka, M; Yajima, Y | 1 |
| Bouma, DJ; Hart, JS; Phillipson, BE; Riddle, MC; Youker, G | 1 |
| Belfiore, F; Campione, R; Castorina, S; Iannello, S; Rabuazzo, AM; Urzi, F | 1 |
| Gepts, W; Gorus, FK; In't Veld, PA; Pipeleers, DG; Schuit, FC | 1 |
| Efendić, S; Ostenson, CG | 1 |
| Ibayashi, H; Sako, Y; Umeda, F; Wasada, T | 1 |
| Flatt, PR; Marks, V; Swanston-Flatt, SK; Tan, KS; Webster, JD | 1 |
| Geisen, K | 1 |
| Beastall, GH; Buchanan, KD; Omile, C; Paterson, KR; Semple, CG | 1 |
| Cherrington, AD; Green, DR; McGuinness, OP | 1 |
| Efendić, S; Grill, V; Gutniak, M; Nylén, A; Ostenson, CG | 1 |
| Borisova, AM; Kirilov, G; Koev, D | 1 |
| Berger, M; Kemmer, FW; Tacken, M | 1 |
| DeFronzo, RA; Groop, L; Groop, PH; Luzi, L; Melander, A; Ratheiser, K; Simonson, DC | 1 |
| Lockwood, D; Nair, KS; Welle, S | 1 |
| Bierwolf, B; Brunner, E; Danneberg, G; Pohl, A; Verlohren, HJ | 1 |
| Galione, A; Hopps, V; Sorrentino, MC; Vaccaro, F; Vetri, P; Woodrow, ME | 1 |
| Groop, L; Harno, K; Nikkilä, EA; Pelkonen, R; Tolppanen, EM | 1 |
| Bowers, CY; Kosola, JW; Prosser, PR | 1 |
| Fajardo, F; Ginier, P; Levin, SR; Madan, S | 1 |
| Fyhrqvist, F; Groop, L; Groop, PH; Melander, A; Tolppanen, EM; Tötterman, KJ; Wåhlin-Boll, E | 1 |
| Howell, SL; Montague, W | 2 |
| Marco, J; Valverde, I | 1 |
| Addah, SA; Crockford, PM; Powell, P | 1 |
| Sweet, RD | 1 |
| Ide, T; Kajinuma, H; Kuzuya, TT | 1 |
| Loubatières, A; Loubatières-Mariani, MM | 1 |
| Jeanrenaud, B; Kanazawa, Y; Lambert, AE; Orci, L; Renold, AE | 1 |
| Edwards, JC; Howell, SL; Montague, W | 1 |
| Ebert, R; Hillebrandt, O; Schwabe, U | 1 |
| Schatz, H | 1 |
| Efendić, S; Grill, V; Nylén, A; Ostensson, CG | 1 |
| Brunetti, P; Filipponi, P; Marcelli, M; Nicoletti, I; Pacifici, R; Santeusanio, F | 1 |
| Efendić, S; Grill, V; Nylén, A; Ostenson, CG | 2 |
| Barras, E; Fletcher, DJ; Grogan, WM; Weir, GC | 1 |
| Barbarino, A; De Marinis, L | 1 |
| Best, L; Malaisse, WJ | 1 |
| Gerard, J; Lefebvre, PJ; Luyckx, AS | 1 |
| Ahrén, B; Lundquist, I | 1 |
| Lohmann, D; Verlohren, HJ | 1 |
| Funai, T; Hinata, S; Ichiyama, A; Matsukage, T; Nishi, S; Yoshimi, T | 1 |
| Björkling, F; Leclercq-Meyer, V; Malaisse, WJ; Sener, A; Zhang, TM | 1 |
| Abiru, N; Akazawa, S; Ishibasi, M; Kawasaki, E; Matsumoto, K; Matsuo, H; Uotani, S; Yamamoto, H; Yamasaki, H; Yano, M | 1 |
| Dan, K; Fujita, T; Hirose, H; Ito, K; Kanda, N; Kato, R; Maruyama, H; Saruta, T; Seto, Y | 1 |
| Beljic, T; Miric, M | 1 |
| Buettger, C; Epstein, AJ; Hang, TL; Matschinsky, FM; Ronner, P | 1 |
| Balázsi, I; Hargitai, G; Takács, J | 1 |
| Abourizk, NN; Lyons, RW; Madden, GM | 1 |
| Ditzler, TM; Gumbiner, B; Henry, RR; Joyce, M; Murata, C; Song, YM; Suh, KI | 1 |
| Habener, JF; Holz, GG; Kühtreiber, WM | 1 |
| Atillasoy, EJ; Burtis, WJ; Gaich, G; Ganz, MB; Orloff, JJ; Stewart, AF | 1 |
| Andrews, KM; Hargrove, DM; Nardone, NA; Parker, JC; Persson, LM; Shepherd, KL; Stevenson, RW | 1 |
| Adrogue, HJ; Comstock, JP; Pena, J | 1 |
| Genuth, S; Glauser, J; Thoma, ME | 1 |
| Efendic, S; Guenifi, A; Gutniak, MK; Hellström, PM; Holst, JJ; Juntti-Berggren, L | 1 |
| Birkenholz, M; Kabadi, M; Kabadi, UM; McCoy, S | 1 |
| Komatsu, M; Noda, M; Sharp, GW | 1 |
| Anderson, BD; Anderson, DL; Fenn, J; Gorman, SE; Krenzelok, EP; Muir, SJ; Rodgers, GC; Rose, SR; Spiller, HA; Villalobos, D | 1 |
| Ali, BH | 1 |
| Bungert, S; Gudat, U; Heinemann, L; Kemmer, F | 1 |
| Bataille, D; Blache, P; Dalle, S; Le Brigand, L; Le-Nguyen, D | 1 |
| Adamson, U; Landstedt-Hallin, L; Lins, PE | 1 |
| Dela, F; Galbo, H; Larsen, JJ; Madsbad, S; Vibe-Petersen, J | 1 |
| Efendic, S; Kindmark, H; Pigon, J | 1 |
| Appelman, AM; Erkelens, DW; ter Braak, EW; van der Tweel, I; van Haeften, TW | 1 |
| De Proft, R; Dejonghe, S; Gorus, F; Ling, Z; Pipeleers, D; Schuit, F; Winnock, F | 1 |
| Andersson, G; Efendic, S; Grill, V; Kärvestedt, L | 1 |
| Briaud, I; Dickson, LM; Lingohr, MK; Rhodes, CJ; Wrede, CE | 1 |
| Gribble, FM; Reimann, F; Simpson, AK; Williams, L | 1 |
| Alvarsson, M; Berntorp, K; Fernqvist-Forbes, E; Grill, V; Henricsson, M; Lager, I; Orn, T; Steen, L; Sundkvist, G; Westermark, G; Westermark, P | 1 |
| Carr, RD; Degn, KB; Gall, MA; Rizza, RA; Schmitz, O; Thomsen, MK; Veldhuis, JD; Østergård, T | 1 |
| Corll, C; Martin, RJ; Porter, JR; Roane, DS; Zhang, Y; Zhou, J | 1 |
| Croom, DK; Lenhard, JM; Minnick, DT | 1 |
| Edwardson, JM; Hays, LB; McCuaig, JF; Philipson, LH; Rhodes, CJ; Wang, Y; Wicksteed, B | 1 |
| Groop, LC; Honkanen, EH; Isomaa, B; Sarelin, L; Tuomi, T | 1 |
| Choi, HS; Choi, HY; Kang, SM; Kim, JD; Ku, SK; Seo, BI | 1 |
| Buettger, CW; Carr, RD; Collins, HW; Doliba, NM; Kaestner, KH; Magnuson, MA; Matschinsky, FM; Qin, W; Vatamaniuk, MZ; Wilson, DF | 1 |
| Doliba, NM; Gupta, RK; Kaestner, KH; Lantz, KA; Matschinsky, FM; Vatamaniuk, MZ | 1 |
| Alvarsson, M; Berntorp, K; Fernqvist-Forbes, E; Grill, V; Holberg, MA; Kirksaether, N; Lager, I; Orn, T; Steen, L; Sundkvist, G | 1 |
| El-Ouaghlidi, A; Foley, J; Holmes, D; Holst, JJ; Nauck, MA; Rehring, E; Schweizer, A | 1 |
| Anderson, K; Bar-Zeev, N; Fahy, R; Rath, S; Roseby, R | 1 |
| Cauchi, S; Choquet, H; D'Aleo, V; Del Guerra, S; Froguel, P; Groves, CJ; Lupi, R; Marchetti, P; McCarthy, MI | 1 |
| Chen, B; Ernsberger, P; Escobedo, LV; Hou, D; Koletsky, MS; Koletsky, RJ; Moore, A | 1 |
| Alvarsson, M; Berntorp, K; Fernqvist-Forbes, E; Grill, V; Lager, I; Orn, T; Steen, L | 1 |
| Davis, SN; Joy, NG; Tate, DB | 1 |
| Emfinger, CH; Hruz, PW; Hung, P; McAllister, W; Nichols, CG; Remedi, MS; Welscher, A; Yan, Z | 1 |
| Bennett, RC; Kallio-Kujala, IJ; Meierjohann, A; Raekallio, MR; Savontaus, E; Scheinin, M; Spillmann, T; Vainio, OM; Yatkin, E | 1 |
| Akheruzzaman, M; Dhurandhar, NV; Feizy, Z; Hegde, V; Shin, AC; Siddik, MAB | 1 |
| Chalk, R; Gough, S; Rorsman, P; Spiliotis, II | 1 |
2 review(s) available for glucagon and glyburide
| Article | Year |
|---|---|
Glibenclamide: a review.
Topics: Administration, Oral; Adolescent; Adult; Aged; Animals; Biguanides; Blood Glucose; Carbon Isotopes; Child; Chlorpropamide; Diabetes Mellitus; Dogs; Drug Interactions; Drug Synergism; Female; Fibrinolysis; Glucagon; Glucose; Glyburide; Guinea Pigs; Humans; Hypoglycemia; In Vitro Techniques; Insulin; Islets of Langerhans; Lipids; Liver Glycogen; Pancreas; Pregnancy; Protein Binding; Rabbits; Rats; Stimulation, Chemical; Sulfonylurea Compounds | 1971 |
Meta-analysis and functional effects of the SLC30A8 rs13266634 polymorphism on isolated human pancreatic islets.
Topics: Arginine; Asian People; Cation Transport Proteins; Diabetes Mellitus, Type 2; Genotype; Glucagon; Glucose; Glyburide; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Polymorphism, Genetic; Risk; White People; Zinc Transporter 8 | 2010 |
25 trial(s) available for glucagon and glyburide
| Article | Year |
|---|---|
[Clinical investigations of the effect of tolbutamide and glibenclamide on pancreatic glucagon secretion (author's transl)].
Topics: Adult; Arginine; Blood Glucose; Glucagon; Glyburide; Humans; Insulin; Male; Pancreas; Tolbutamide | 1975 |
Effect of glyburide and omega 3 fatty acid dietary supplements on glucose and lipid metabolism in patients with non-insulin-dependent diabetes mellitus.
Topics: Aged; Blood Glucose; Diabetes Mellitus, Type 2; Fatty Acids; Fatty Acids, Omega-3; Glucagon; Glucose; Glyburide; Humans; Insulin; Lipid Metabolism; Lipoproteins; Male; Middle Aged | 1992 |
Combination of insulin with glipizide increases peripheral glucose disposal in secondary failure type 2 diabetic patients.
Topics: Aged; Blood Glucose; C-Peptide; Cholesterol; Cholesterol Esters; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Glipizide; Glucagon; Glucose Clamp Technique; Glyburide; Glycated Hemoglobin; Humans; Insulin; Lipoproteins; Male; Middle Aged; Sulfonylurea Compounds | 1990 |
Efficacy of bedtime NPH insulin with daytime sulfonylurea for subpopulation of type II diabetic subjects.
Topics: Adult; Aged; Blood Glucose; C-Peptide; Clinical Trials as Topic; Diabetes Mellitus, Type 1; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Eating; Fasting; Glucagon; Glyburide; Humans; Insulin, Isophane; Middle Aged; Random Allocation | 1989 |
Effect of oral verapamil on glibenclamide stimulated insulin secretion.
Topics: Adult; C-Peptide; Glucagon; Glucose; Glyburide; Humans; Hypoglycemia; Insulin; Insulin Secretion; Male; Verapamil | 1986 |
Transient effect of the combination of insulin and sulfonylurea (glibenclamide) on glycemic control in non-insulin dependent diabetics poorly controlled with insulin alone.
Topics: Blood Glucose; Body Weight; C-Peptide; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Female; Glucagon; Glyburide; Glycated Hemoglobin; Glycosuria; Humans; Insulin; Lipids; Male; Middle Aged | 1985 |
The 24-hour effects of glyburide and chlorpropamide after chronic treatment of type II diabetic patients.
Topics: Adult; Aged; Blood Glucose; Chlorpropamide; Cholesterol; Diabetes Mellitus, Type 2; Drug Evaluation; Female; Glucagon; Glyburide; Growth Hormone; Humans; Insulin; Male; Middle Aged; Radioimmunoassay; Random Allocation; Time Factors; Triglycerides | 1985 |
Once-daily use of glyburide.
Topics: Blood Glucose; Body Weight; Chlorpropamide; Diabetes Mellitus, Type 2; Drug Administration Schedule; Glucagon; Glyburide; Glycosuria; Humans; Insulin | 1985 |
Pharmacokinetics and metabolic effects of glibenclamide and glipizide in type 2 diabetics.
Topics: Aged; Blood Glucose; Body Weight; C-Peptide; Diabetes Mellitus, Type 2; Double-Blind Method; Erythrocytes; Female; Gastric Inhibitory Polypeptide; Glipizide; Glucagon; Glyburide; Glycosuria; Humans; Insulin; Insulin Resistance; Kinetics; Male; Middle Aged; Random Allocation; Sulfonylurea Compounds | 1985 |
Glibenclamide pharmacokinetics in acarbose-treated type 2 diabetics.
Topics: Acarbose; Blood Glucose; Diabetes Mellitus, Type 2; Double-Blind Method; Glucagon; Glyburide; Humans; Hypoglycemic Agents; Insulin; Kinetics; Male; Middle Aged; Oligosaccharides; Random Allocation; Trisaccharides | 1984 |
Insulin response after treatment depends on fasting plasma glucose level in NIDDM.
Topics: Adult; Blood Glucose; Body Mass Index; C-Peptide; Diabetes Mellitus, Type 2; Diet, Diabetic; Fasting; Female; Gliclazide; Glucagon; Glucose Tolerance Test; Glyburide; Humans; Insulin; Male; Middle Aged | 1994 |
Improved metabolic control does not reverse left ventricular filling abnormalities in newly diagnosed non-insulin-dependent diabetes patients.
Topics: Adult; Blood Glucose; Blood Pressure; C-Peptide; Chlorpropamide; Cholesterol; Diabetes Mellitus, Type 2; Diet, Diabetic; Echocardiography, Doppler; Female; Follow-Up Studies; Glucagon; Glyburide; Glycated Hemoglobin; Heart Rate; Humans; Male; Middle Aged; Reference Values; Triglycerides; Ventricular Function, Left | 1994 |
Glucagon-like peptide I enhances the insulinotropic effect of glibenclamide in NIDDM patients and in the perfused rat pancreas.
Topics: Analysis of Variance; Animals; Diabetes Mellitus, Type 2; Drug Synergism; Drug Therapy, Combination; Gastric Emptying; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glyburide; Humans; In Vitro Techniques; Infusions, Intravenous; Insulin; Insulin Secretion; Islets of Langerhans; Middle Aged; Peptide Fragments; Perfusion; Protein Precursors; Rats; Rats, Sprague-Dawley; Treatment Failure | 1996 |
More uniform diurnal blood glucose control and a reduction in daily insulin dosage on addition of glibenclamide to insulin in type 1 diabetes mellitus: role of enhanced insulin sensitivity.
Topics: Adult; Aged; Blood Glucose; Body Weight; C-Peptide; Cholesterol; Circadian Rhythm; Cross-Over Studies; Diabetes Mellitus, Type 1; Double-Blind Method; Drug Therapy, Combination; Glucagon; Glyburide; Glycated Hemoglobin; Glycosuria; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Male; Middle Aged; Placebos; Triglycerides | 1995 |
The blood glucose lowering effects of exercise and glibenclamide in patients with type 2 diabetes mellitus.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Exercise; Glucagon; Glyburide; Humans; Hypoglycemic Agents; Insulin; Lactic Acid; Middle Aged | 1998 |
The sulfonylurea glyburide induces impairment of glucagon and growth hormone responses during mild insulin-induced hypoglycemia.
Topics: Adult; Blood Glucose; Body Mass Index; Female; Glucagon; Glucose Clamp Technique; Glyburide; Human Growth Hormone; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Male; Placebos; Reference Values | 2002 |
A rapid increase in beta-cell function by multiple insulin injections in type 2 diabetic patients is not further enhanced by prolonging treatment.
Topics: Blood Glucose; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Glucagon; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Insulin Secretion; Islets of Langerhans; Male; Middle Aged | 2002 |
Beneficial effects of insulin versus sulphonylurea on insulin secretion and metabolic control in recently diagnosed type 2 diabetic patients.
Topics: Adult; Aged; Amyloid; Blood Glucose; Body Weight; C-Peptide; Cholesterol, HDL; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Follow-Up Studies; Glucagon; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Insulin Secretion; Islet Amyloid Polypeptide; Islets of Langerhans; Male; Middle Aged; Proinsulin; Quality of Life | 2003 |
The insulin secretagogues glibenclamide and repaglinide do not influence growth hormone secretion in humans but stimulate glucagon secretion during profound insulin deficiency.
Topics: Blood Glucose; C-Peptide; Carbamates; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Glucagon; Glucose Clamp Technique; Glyburide; Growth Hormone-Releasing Hormone; Human Growth Hormone; Humans; Hypoglycemic Agents; Insulin; Piperidines; Placebos; Potassium Channel Blockers; Somatostatin | 2004 |
Improved prandial glucose control with lower risk of hypoglycemia with nateglinide than with glibenclamide in patients with maturity-onset diabetes of the young type 3.
Topics: Adult; Aged; Blood Glucose; C-Peptide; Cross-Over Studies; Cyclohexanes; Diabetes Mellitus, Type 2; Double-Blind Method; Exercise Test; Female; Glucagon; Glyburide; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Male; Middle Aged; Nateglinide; Phenylalanine; Postprandial Period | 2006 |
Effects of insulin vs. glibenclamide in recently diagnosed patients with type 2 diabetes: a 4-year follow-up.
Topics: Adult; Aged; Blood Glucose; Body Weight; C-Peptide; Diabetes Mellitus, Type 2; Drug Administration Schedule; Fasting; Female; Follow-Up Studies; Glucagon; Glyburide; Glycated Hemoglobin; Health Status Indicators; Humans; Hypoglycemic Agents; Insulin; Insulin-Secreting Cells; Insulin, Long-Acting; Lipids; Male; Middle Aged; Proinsulin; Quality of Life | 2008 |
The dipeptidyl peptidase 4 inhibitor vildagliptin does not accentuate glibenclamide-induced hypoglycemia but reduces glucose-induced glucagon-like peptide 1 and gastric inhibitory polypeptide secretion.
Topics: Adamantane; Adult; Algorithms; C-Peptide; Dipeptidyl-Peptidase IV Inhibitors; Drug Interactions; Enzyme-Linked Immunosorbent Assay; Gastric Emptying; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucose; Glyburide; Humans; Hydrocortisone; Hypoglycemia; Hypoglycemic Agents; Insulin; Male; Nitriles; Pyrrolidines; Vildagliptin | 2007 |
Effects of insulin versus sulphonylurea on beta-cell secretion in recently diagnosed type 2 diabetes patients: a 6-year follow-up study.
Topics: Adult; Aged; C-Peptide; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Glucagon; Glyburide; Humans; Hypoglycemic Agents; Insulin; Insulin Secretion; Insulin-Secreting Cells; Male; Middle Aged | 2010 |
Counterregulatory responses to hypoglycemia differ between glimepiride and glyburide in non diabetic individuals.
Topics: Adult; Blood Glucose; C-Peptide; Female; Glucagon; Glucose Clamp Technique; Glyburide; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Leptin; Male; Pancreatic Polypeptide; Single-Blind Method; Sulfonylurea Compounds | 2015 |
Effects of dexmedetomidine and MK-467 on plasma glucose, insulin and glucagon in a glibenclamide-induced canine hypoglycaemia model.
Topics: Adrenergic alpha-2 Receptor Agonists; Anesthesia, Intravenous; Animals; Blood Glucose; Cross-Over Studies; Dexmedetomidine; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Glucagon; Glyburide; Hypnotics and Sedatives; Hypoglycemia; Hypoglycemic Agents; Insulin; Male; Quinolizines; Random Allocation; Treatment Outcome | 2018 |
89 other study(ies) available for glucagon and glyburide
| Article | Year |
|---|---|
The effect of glibenclamide treatment on the insulin and glucagon responses to oral glucose and galactose in maturity onset diabetics.
Topics: Aged; Diabetes Mellitus; Female; Galactose; Glucagon; Glucose Tolerance Test; Glyburide; Humans; Insulin; Male; Middle Aged | 1979 |
Effect of glucose/sulfonylurea interaction on release of insulin, glucagon, and somatostatin from isolated perfused rat pancreas.
Topics: Animals; Dose-Response Relationship, Drug; Drug Interactions; Glucagon; Glucose; Glyburide; Insulin; Insulin Secretion; Islets of Langerhans; Perfusion; Rats; Somatostatin | 1979 |
Diabetes newly diagnosed during pregnancy: A 4-year study at Groote Schuur Hospital.
Topics: Adolescent; Adult; Birth Weight; Black or African American; Black People; Delivery, Obstetric; Diabetes Mellitus; Female; Glucagon; Glucose Tolerance Test; Glyburide; Humans; Infant Mortality; Insulin; Ketones; Labor, Obstetric; Metformin; Pregnancy; Pregnancy in Diabetics; South Africa; White People | 1979 |
[Action of glibenclamide on glucagon and insulin secretions studied on isolated and perfused pancreas of the rat].
Topics: Animals; Blood Glucose; Glucagon; Glyburide; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Perfusion; Rats; Secretory Rate; Stimulation, Chemical | 1975 |
Hyaluronidase-induced inhibition of the insulinotropic action of sulfonylureas, leucine, and glucagon in rodent isolated pancreatic islets.
Topics: Animals; Chlorpropamide; Cricetinae; Female; Glucagon; Glucose; Glyburide; Hyaluronoglucosaminidase; Insulin; Islets of Langerhans; Leucine; Mice; Microbial Collagenase; Rats; Species Specificity; Sulfonylurea Compounds; Tolbutamide | 1976 |
Inhibition of the glucose induced insulin release by somatostatin in the isolated perfused rat pancreas. Action of cyclic AMP, glucagon and glibenclamide.
Topics: Animals; Cyclic AMP; Glucagon; Glucose; Glyburide; Insulin; Insulin Antagonists; Insulin Secretion; Pancreas; Rats; Somatostatin; Stimulation, Chemical | 1976 |
Studies on the mode of action of somatostatin on insulin secretion.
Topics: Animals; Arginine; Cyclic AMP; Glucagon; Glucose; Glyburide; In Vitro Techniques; Insulin; Insulin Secretion; Male; Pancreas; Phentolamine; Potassium Chloride; Rats; Somatostatin | 1977 |
The metabolism of cyclic AMP and glucose in isolated islets from Acomys cahirinus.
Topics: Animals; Cyclic AMP; Female; Glucagon; Glucose; Glyburide; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Mice | 1979 |
Glucagon release from rat pancreatic islets. A combined morphological and functional approach.
Topics: Animals; Arginine; Calcium; Exocytosis; Freeze Fracturing; Glucagon; Glucose; Glyburide; In Vitro Techniques; Islets of Langerhans; Microscopy, Electron; Rats | 1977 |
Glucagon and growth hormone secretion in insulin-treated diabetics: effects of added sulfonylureas.
Topics: Adult; Arginine; Diabetes Mellitus, Type 1; Female; Glucagon; Glyburide; Growth Hormone; Humans; Insulin; Male; Middle Aged | 1978 |
[Effect of tolbutamide and glibenclamide on glucagon secretion in subjects with normal metabolism and in diabetics].
Topics: Adult; Diabetes Mellitus; Glucagon; Glyburide; Humans; Male; Tolbutamide | 1975 |
Therapeutical concentrations of tolbutamide, glibenclamide, gliclazide and gliquidone at different glucose levels: in vitro effects on pancreatic A- and B-cell function.
Topics: Animals; Blood Glucose; Dose-Response Relationship, Drug; Gliclazide; Glucagon; Glucose; Glyburide; Hypoglycemic Agents; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Perfusion; Rats; Rats, Sprague-Dawley; Sulfonylurea Compounds; Time Factors; Tolbutamide | 1992 |
The dawn phenomenon and diabetes control in treated NIDDM and IDDM patients.
Topics: Blood Glucose; Circadian Rhythm; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Glucagon; Glyburide; Glycated Hemoglobin; Growth Hormone; Humans; Hydrocortisone; Insulin; Male; Middle Aged | 1992 |
Relationship between blood pressure and in vivo action of insulin in type II (non-insulin-dependent) diabetic subjects.
Topics: Antihypertensive Agents; Blood Pressure; C-Peptide; Diabetes Mellitus, Type 2; Diet, Diabetic; Female; Glucagon; Glucose Clamp Technique; Glyburide; Glycated Hemoglobin; Humans; Hypertension; Infusions, Intravenous; Insulin; Male; Metformin; Middle Aged; Regression Analysis | 1992 |
Sulfonylurea enhances insulin-induced acetyl coenzyme A carboxylase activity in rat adipocytes.
Topics: Acetyl-CoA Carboxylase; Adipose Tissue; Animals; Enzyme Induction; Epinephrine; Glucagon; Glyburide; In Vitro Techniques; Insulin; Male; Rats; Rats, Inbred Strains; Sulfonylurea Compounds; Tolbutamide | 1991 |
Co-secretion of amylin and insulin from cultured islet beta-cells: modulation by nutrient secretagogues, islet hormones and hypoglycemic agents.
Topics: Amyloid; Animals; Arginine; Cell Line; Cricetinae; Glucagon; Glucose; Glyburide; Humans; Hypoglycemic Agents; Insulin; Insulin Secretion; Islet Amyloid Polypeptide; Islets of Langerhans; Kinetics; Metformin; Somatostatin; Tolbutamide | 1991 |
Effects of porcine diazepam-binding inhibitor on insulin and glucagon secretion in vitro from the rat endocrine pancreas.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Diazepam Binding Inhibitor; Glucagon; Glucose; Glyburide; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Neuropeptides; Rats; Rats, Inbred Strains; Somatostatin; Stimulation, Chemical; Swine | 1990 |
Effect of nerve blockade on pulsatile insulin and glucagon secretion in vitro.
Topics: Animals; Atropine; Biological Clocks; Female; Glucagon; Glyburide; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Mice; Nervous System; Nervous System Physiological Phenomena; Phentolamine; Propranolol; Tetrodotoxin | 1991 |
Effects of glimepiride and glibenclamide on insulin and glucagon secretion by the perfused rat pancreas.
Topics: Animals; Female; Glucagon; Glyburide; Hypoglycemic Agents; Insulin; Insulin Secretion; Pancreas; Perfusion; Rats; Rats, Inbred Strains; Sulfonylurea Compounds; Time Factors | 1991 |
Effect of long-term administration of insulin and glibenclamide on pancreatic A and B cell function.
Topics: Animals; Arginine; Blood Glucose; Glucagon; Glucose Tolerance Test; Glyburide; Hyperinsulinism; Insulin; Islets of Langerhans; Male; Rats; Rats, Inbred Strains | 1990 |
Usefulness of anaerobic threshold in estimating intensity of exercise for diabetics.
Topics: Adult; Anaerobiosis; Blood Glucose; Buformin; Diabetes Mellitus, Type 2; Exercise; Female; Glucagon; Glyburide; Humans; Insulin; Lactates; Male; Middle Aged; Oxygen Consumption; Pyruvates; Reference Values | 1989 |
Extra-pancreatic action of glibenclamide in man: reduction in vitro of the inhibitory effect of glucagon and epinephrine on the hepatic key glycolytic enzymes phosphofructokinase (PFK) and pyruvate kinase (PK).
Topics: Adult; Animals; Drug Interactions; Epinephrine; Female; Glucagon; Gluconeogenesis; Glyburide; Glycolysis; Humans; Liver; Male; Mice; Middle Aged; Phosphofructokinase-1; Pyruvate Kinase | 1989 |
Interaction of sulfonylureas with pancreatic beta-cells. A study with glyburide.
Topics: Animals; Cyclic AMP; Glucagon; Glucose; Glyburide; Insulin; Insulin Secretion; Islets of Langerhans; Male; Oxidation-Reduction; Rats; Rats, Inbred Strains; Tolbutamide | 1988 |
Cysteamine exerts multiple effects on the endocrine cells of the rat pancreas.
Topics: Animals; Blood Glucose; Culture Techniques; Cysteamine; Glucagon; Glucose; Glyburide; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Oxidation-Reduction; Rats; Rats, Inbred Strains; Somatostatin | 1985 |
Effect of glibenclamide on pancreatic hormone release from isolated perifused islets of normal and cysteamine-treated rats.
Topics: Animals; Arginine; Cysteamine; Dose-Response Relationship, Drug; Glucagon; Glyburide; Insulin; Islets of Langerhans; Male; Pancreatic Hormones; Rats; Rats, Inbred Strains; Somatostatin | 1986 |
Metabolic effects and secretory properties of a radiation-induced transplantable rat insulinoma.
Topics: Adenoma, Islet Cell; Animals; Arginine; Blood Glucose; Body Weight; Deoxyglucose; Epinephrine; Feeding Behavior; Glucagon; Glyburide; Insulin; Insulinoma; Male; Neoplasms, Radiation-Induced; Pancreatic Neoplasms; Rats; Rats, Inbred Strains | 1987 |
Special pharmacology of the new sulfonylurea glimepiride.
Topics: Administration, Oral; Animals; Blood Glucose; Chemical Phenomena; Chemistry; Dogs; Female; Glucagon; Glucose; Glyburide; Hypoglycemic Agents; Injections, Intravenous; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Lactates; Male; Pancreas; Rabbits; Rats; Somatostatin; Sulfonylurea Compounds | 1988 |
Glyburide sensitizes perfused rat liver to insulin-induced suppression of glucose output.
Topics: Animals; Glucagon; Glucose; Glyburide; Insulin; Liver; Male; Phosphorylase a; Rats; Rats, Inbred Strains | 1987 |
Sulfonylurea-induced inhibition of glucagon secretion from the perfused rat pancreas: evidence for a direct, non-paracrine effect.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Glucagon; Glyburide; In Vitro Techniques; Male; Pancreas; Perfusion; Rats; Rats, Inbred Strains; Sulfonylurea Compounds; Tolazamide | 1986 |
[Possibility of transferring patients with type-II diabetes mellitus treated with small doses of sulfonylurea preparations to diet therapy].
Topics: Adult; Aged; Blood Glucose; C-Peptide; Chronic Disease; Diabetes Mellitus, Type 2; Female; Glucagon; Glyburide; Humans; Insulin; Insulin Secretion; Male; Middle Aged; Sulfonylurea Compounds | 1987 |
Mechanism of exercise-induced hypoglycemia during sulfonylurea treatment.
Topics: Adult; C-Peptide; Glucagon; Glyburide; Humans; Hypoglycemia; Insulin; Kinetics; Lactates; Lactic Acid; Male; Physical Exertion | 1987 |
Different effects of glyburide and glipizide on insulin secretion and hepatic glucose production in normal and NIDDM subjects.
Topics: Adult; Aged; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Gastric Inhibitory Polypeptide; Glipizide; Glucagon; Glucose; Glyburide; Humans; Hyperglycemia; Insulin; Insulin Secretion; Kinetics; Liver; Sulfonylurea Compounds | 1987 |
Effect of a sulfonylurea and insulin on energy expenditure in type II diabetes mellitus.
Topics: Blood Glucose; Blood Urea Nitrogen; C-Peptide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Energy Metabolism; Epinephrine; Female; Glucagon; Glyburide; Glycosuria; Humans; Insulin; Male; Middle Aged; Norepinephrine; Obesity | 1988 |
[Insulin therapy of obese diabetic patients? Consequences for the evaluation of insulin secretion and metabolic behavior].
Topics: Combined Modality Therapy; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diet, Diabetic; Energy Metabolism; Female; Glucagon; Glucose Tolerance Test; Glyburide; Humans; Insulin; Male; Middle Aged; Obesity | 1987 |
Glybenclamide and cyclosporine A: an interaction on glucose metabolism.
Topics: Animals; C-Peptide; Cyclosporins; Drug Interactions; Glucagon; Glucose; Glyburide; Glycogen; Insulin; Rats | 1988 |
Adenylate cyclase activity in isolated rat islets of Langerhans. Effects of agents which alter rates of insulin secretion.
Topics: Adenylyl Cyclases; Animals; Arginine; Epinephrine; Fluorides; Glucagon; Glucose; Glyburide; Guanosine Triphosphate; Hydrogen-Ion Concentration; In Vitro Techniques; Islets of Langerhans; Isoproterenol; Kinetics; Leucine; Male; Norepinephrine; Nucleotides; Phenoxybenzamine; Phosphorus Radioisotopes; Potassium; Propranolol; Prostaglandins; Rats; Xylitol | 1973 |
Unaltered glucagon secretion after seven days of sulphonylurea administration in normal subjects.
Topics: Administration, Oral; Arginine; Blood Glucose; Cyclohexanes; Drug Evaluation; Female; Glucagon; Glyburide; Humans; Hypoglycemic Agents; Injections, Intravenous; Insulin; Male; Methods; Pancreas; Pyrazines; Sulfonylurea Compounds | 1973 |
Effect of sulfonylureas on the secretion of pancreatic immunoreactive glucagon and enteric glucagon-like immunoreactivity.
Topics: Animals; Antibody Formation; Antigens; Arginine; Glucagon; Glucose; Glyburide; In Vitro Techniques; Insulin Antibodies; Pancreas; Radioimmunoassay; Rats; Sulfonylurea Compounds; Theophylline; Tolbutamide | 1973 |
A dermatosis specifically associated with a tumour of pancreatic alpha cells.
Topics: Blister; Blood Glucose; Body Weight; Diabetes Complications; Female; Glucagon; Glucose; Glucose Tolerance Test; Glyburide; Glycosuria; Humans; Immunoglobulin A; Immunoglobulin M; Insulin; Keratosis; Middle Aged; Pancreatectomy; Pancreatic Neoplasms; Skin Diseases; Splenectomy; Stress, Psychological | 1974 |
Effects of hypoglycemic sulfonamides on glucagon and insulin secretion in ducks and dogs.
Topics: Animals; Antigens; Arteries; Blood Glucose; Carboxylic Acids; Dogs; Ducks; Ethers; Femoral Artery; Glucagon; Glyburide; Hypoglycemic Agents; Injections, Intravenous; Insulin; Insulin Secretion; Pancreas; Pyrimidines; Species Specificity; Sulfonamides; Tolbutamide; Veins | 1974 |
In vitro secretion of insulin after glucose, sulphonylureas, adrenergic and cholinergic substances studied by isolated perfused rat pancreas.
Topics: Acetylcholine; Animals; Atropine; Diazoxide; Epinephrine; Glucagon; Glucose; Glyburide; Heptoses; In Vitro Techniques; Insulin; Insulin Secretion; Isoproterenol; Ketoses; Norepinephrine; Pancreas; Parasympathomimetics; Perfusion; Phenoxybenzamine; Practolol; Propranolol; Sulfonylurea Compounds; Theophylline; Tolbutamide | 1974 |
Biochemical and morphological events associated with the development of fetal rat pancreas "in vivo" and "in vitro": effect of glucagon and of other agents.
Topics: Animals; Caffeine; Cell Differentiation; Culture Techniques; Cyclic AMP; Glucagon; Glucose; Glyburide; Insulin; Insulin Secretion; Islets of Langerhans; Pancreas; Pyruvates; Rats; Sulfonylurea Compounds; Tolbutamide | 1970 |
The mode of action of adenosine 3':5'-cyclic monophosphate in mammalian islets of Langerhans. Effects of insulin secretagogues on islet-cell protein kinase activity.
Topics: Animals; Arginine; Caffeine; Cyclic AMP; Diazoxide; Epinephrine; Glucagon; Glyburide; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; Phosphorus Isotopes; Phosphotransferases; Protein Kinases; Rats; Theophylline; Time Factors; Tolbutamide; Xanthines; Xylitol | 1973 |
Regulation of adenylate cyclase and cyclic-AMP dependent protein kinase activities in A2-cell rich guinea-pig islets of Langerhans.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Arginine; Bucladesine; Cyclic AMP; Diazoxide; Epinephrine; Fluorides; Glucagon; Glyburide; Guinea Pigs; Islets of Langerhans; Leucine; Male; Microbial Collagenase; Phosphorus Radioisotopes; Protein Kinases; Radioimmunoassay; Streptozocin; Theophylline | 1974 |
Role of calcium and cyclic adenosine 3',5'-monophosphate in the antilipolytic effect of tolbutamide and glibenclamide.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adipose Tissue; Adrenocorticotropic Hormone; Animals; Bucladesine; Calcium; Carboxylic Acids; Cyclic AMP; Epinephrine; Glucagon; Glyburide; Isoproterenol; Lipid Metabolism; Male; Norepinephrine; Rats; Theophylline; Tolbutamide | 1974 |
[The pancreatic beta-cell in the field of current diabetology].
Topics: Blood Glucose; Cyclic AMP; Diabetes Mellitus; Glucagon; Glucose Tolerance Test; Glyburide; Growth Hormone; Humans; Hyperinsulinism; Insulin; Insulin Secretion; Liver Cirrhosis; Pancreas; Secretory Rate; Theophylline | 1974 |
Sulphonylurea (glubenclamide) enhances somatostatin and inhibits glucagon release induced by arginine.
Topics: Animals; Arginine; Depression, Chemical; Drug Synergism; Glucagon; Glyburide; In Vitro Techniques; Insulin; Insulin Secretion; Pancreas; Rats; Somatostatin; Stimulation, Chemical | 1980 |
Difference in calcium dependency of insulin, glucagon and somatostatin secretion in response to glibenclamide in perfused rat pancreas.
Topics: Animals; Calcium; Egtazic Acid; Glucagon; Glucose; Glyburide; Insulin; Insulin Secretion; Male; Pancreas; Rats; Rats, Inbred Strains; Somatostatin | 1982 |
Suppressive effect of long term sulfonylurea treatment on A, B, and D cells of normal rat pancreas.
Topics: Animals; Arginine; Glucagon; Glucose; Glyburide; Insulin; Insulin Secretion; Islets of Langerhans; Male; Rats; Rats, Inbred Strains; Somatostatin; Time Factors; Tolbutamide | 1983 |
Glibenclamide stimulates and glucose inhibits glucagon release induced by calcium deprivation.
Topics: Animals; Calcium; Glucagon; Glucose; Glyburide; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Rats; Rats, Inbred Strains; Somatostatin | 1984 |
Modulation by IBMX, fasting and experimental diabetes of glibenclamide-induced islet hormone release from the perfused rat pancreas.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Fasting; Glucagon; Glyburide; Insulin; Insulin Secretion; Male; Pancreas; Pancreatic Hormones; Rats; Rats, Inbred Strains; Somatostatin; Theophylline | 1983 |
Hormone release by islet B cell-enriched and A and D cell-enriched populations prepared by flow cytometry.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Flow Cytometry; Glucagon; Glucose; Glyburide; Insulin; Islets of Langerhans; Male; Rats; Rats, Inbred Strains | 1983 |
Calcium antagonists and hormone release. I. Effects of verapamil on insulin release in normal subjects and patients with islet-cell tumor.
Topics: Adenoma, Islet Cell; Adolescent; Adult; Blood Glucose; Female; Glucagon; Glucose Tolerance Test; Glyburide; Humans; Insulin; Insulin Secretion; Male; Pancreatic Neoplasms; Reference Values; Verapamil | 1980 |
Phosphatidylinositol and phosphatidic acid metabolism in rat pancreatic islets in response to neurotransmitter and hormonal stimuli.
Topics: Animals; Arginine; Atropine; Carbachol; Cholecystokinin; Glucagon; Glyburide; Islets of Langerhans; Kinetics; Phosphatidic Acids; Phosphatidylinositols; Phosphorus Radioisotopes; Rats; Thyrotropin | 1983 |
Effects of glucagon and pentagastrin on glibenclamide-induced insulin release.
Topics: Animals; Female; Glucagon; Glyburide; Insulin; Insulin Secretion; Mice; Pentagastrin; Radioimmunoassay | 1980 |
IRI-secretion in MOD with and without SU (5 year control).
Topics: Blood Glucose; Diabetes Mellitus; Glucagon; Glyburide; Humans; Insulin; Middle Aged; Tolbutamide | 1980 |
Regulation of glucokinase gene expression in cultured rat islet cells: the inhibitory effects of T3 and glucagon, and the stimulatory effect of glibenclamide.
Topics: Animals; Base Sequence; Bucladesine; Cells, Cultured; Cyclic GMP; Cycloheximide; DNA, Complementary; Gene Expression Regulation, Enzymologic; Glucagon; Glucokinase; Glucose; Glyburide; Insulin; Islets of Langerhans; Male; Molecular Sequence Data; Rats; Rats, Wistar; RNA, Messenger; Triiodothyronine; Vanadates | 1994 |
Insulinotropic action of the D-glucosyl and 3-O-methyl-D-glucosyl monomethyl esters of succinic acid.
Topics: Animals; Blood Glucose; Esters; Glucagon; Glucose; Glyburide; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Pancreas; Rats; Succinates | 1994 |
Effects of D-phenylalanine-derivative hypoglycemic agent A-4166 on pancreatic alpha- and beta-cells: comparative study with glibenclamide.
Topics: Analysis of Variance; Animals; Cyclohexanes; Diazoxide; Drug Interactions; Glucagon; Glyburide; Hypoglycemic Agents; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Nateglinide; Perfusion; Phenylalanine; Rats; Rats, Wistar | 1995 |
Sulfonylurea-binding sites and ATP-sensitive K+ channels in alpha-TC glucagonoma and beta-TC insulinoma cells.
Topics: Adenosine Triphosphate; Animals; Binding Sites; Binding, Competitive; Diazoxide; Glucagon; Glucagonoma; Glyburide; Insulinoma; Kinetics; Membrane Potentials; Mice; Pancreatic Neoplasms; Potassium Channels; Tolbutamide; Tritium; Tumor Cells, Cultured | 1993 |
[C-peptide levels in secondary sulfonylurea resistant diabetics].
Topics: Aged; C-Peptide; Diabetes Mellitus, Type 2; Drug Resistance; Female; Glucagon; Glyburide; Humans; Insulin; Male; Middle Aged; Sulfonylurea Compounds | 1993 |
Transient state of NIDDM in a patient with AIDS.
Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Glucagon; Glucose Tolerance Test; Glyburide; Humans; Insulin; Male; Pentamidine; Proinsulin | 1993 |
Intracellular glucose metabolism after long term metabolic control with glyburide: improved glucose oxidation with unchanged glycogen synthase activity.
Topics: Blood Glucose; Body Composition; Body Mass Index; C-Peptide; Calorimetry, Indirect; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Female; Glucagon; Glucose; Glucose Clamp Technique; Glyburide; Glycogen Synthase; Humans; Insulin; Male; Middle Aged; Muscles; Obesity; Oxidation-Reduction; Pyruvate Dehydrogenase Complex | 1993 |
Pancreatic beta-cells are rendered glucose-competent by the insulinotropic hormone glucagon-like peptide-1(7-37).
Topics: Animals; Cells, Cultured; Cyclic AMP; Drug Synergism; Electric Conductivity; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glyburide; Islets of Langerhans; Male; Membrane Potentials; Peptide Fragments; Peptides; Rats; Thionucleotides | 1993 |
Amino-terminal parathyroid hormone-related protein: specific binding and cytosolic calcium responses in rat insulinoma cells.
Topics: Animals; Binding Sites; Calcium; Cell Membrane; Cyclic AMP; Cytosol; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glyburide; Insulinoma; Kinetics; Pancreatic Neoplasms; Parathyroid Hormone; Parathyroid Hormone-Related Protein; Peptide Fragments; Peptides; Proteins; Rats; Rats, Inbred WF; Tumor Cells, Cultured | 1993 |
Comparison of the glucose dependency of glucagon-like peptide-1 (7-37) and glyburide in vitro and in vivo.
Topics: Animals; Fasting; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glyburide; Hypoglycemic Agents; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Peptide Fragments; Peptides; Rats; Rats, Sprague-Dawley | 1996 |
Glyburide increases the secretion, tissue uptake, and action of insulin in conscious normal dogs.
Topics: Animals; Dogs; Glucagon; Glucose; Glyburide; Homeostasis; Insulin; Insulin Secretion; Liver | 1996 |
Persistent hypoglycemia and hyperinsulinemia: caution in using glucagon.
Topics: Adrenergic beta-Antagonists; Alcoholism; Atenolol; Glucagon; Glyburide; Humans; Hyperinsulinism; Hypoglycemia; Hypoglycemic Agents; Male; Middle Aged | 1996 |
The betaHC-9 pancreatic beta-cell line preserves the characteristics of progenitor mouse islets.
Topics: Animals; Arginine; Calcium; Carbachol; Cell Division; Cell Line; Glucagon-Like Peptides; Glucose; Glyburide; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; Mice; Neuropeptides; Peptides; Pituitary Adenylate Cyclase-Activating Polypeptide; Rats; Rats, Sprague-Dawley | 1996 |
Prospective multicenter study of sulfonylurea ingestion in children.
Topics: Accidents; Administration, Oral; Blood Glucose; Body Weight; Child; Child, Preschool; Confidence Intervals; Dose-Response Relationship, Drug; Drug Monitoring; Female; Forecasting; Gastrointestinal Agents; Glipizide; Glucagon; Glucose; Glyburide; Hospitalization; Humans; Hypoglycemia; Hypoglycemic Agents; Infant; Infusions, Intravenous; Male; Patient Admission; Poison Control Centers; Prospective Studies; Risk Factors; Sensitivity and Specificity; Sulfonylurea Compounds; Time Factors; Treatment Outcome | 1997 |
The effect on plasma glucose, insulin and glucagon levels of treatment of diabetic rats with the medicinal plant Rhazya stricta and with glibenclamide, alone and in combination.
Topics: Animals; Blood Glucose; Cholesterol; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Drug Interactions; Glucagon; Glyburide; Hypoglycemic Agents; Insulin; Male; Plant Extracts; Plants, Medicinal; Rats; Rats, Wistar | 1997 |
Miniglucagon: a local regulator of islet physiology.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channels; Calcium Channels, L-Type; Cell Line; Cell Membrane; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glyburide; Homeostasis; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Membrane Potentials; Peptide Fragments; Peptides | 1998 |
Oral glibenclamide suppresses glucagon secretion during insulin-induced hypoglycemia in patients with type 2 diabetes.
Topics: Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Epinephrine; Female; Glucagon; Glucose Clamp Technique; Glyburide; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Kinetics; Male; Middle Aged | 1999 |
Interaction of sulfonylureas and exercise on glucose homeostasis in type 2 diabetic patients.
Topics: Blood Glucose; Diabetes Mellitus, Type 2; Epinephrine; Exercise; Exercise Test; Glucagon; Glyburide; Homeostasis; Human Growth Hormone; Humans; Hydrocortisone; Hypoglycemic Agents; Insulin; Middle Aged; Norepinephrine; Oxygen Consumption; Physical Exertion; Sulfonylurea Compounds; Time Factors | 1999 |
Glucose-dependent insulinotropic hormone potentiates the hypoglycemic effect of glibenclamide in healthy volunteers: evidence for an effect on insulin extraction.
Topics: Adult; Blood Glucose; C-Peptide; Drug Synergism; Female; Gastric Inhibitory Polypeptide; Glucagon; Glyburide; Humans; Hypoglycemic Agents; Insulin; Insulin Secretion; Male | 2001 |
Correlation between GABA release from rat islet beta-cells and their metabolic state.
Topics: 1-Methyl-3-isobutylxanthine; 2,4-Dinitrophenol; Adenosine Triphosphate; Animals; Calcium; Culture Media, Conditioned; Cycloheximide; Diazoxide; gamma-Aminobutyric Acid; Glucagon; Glucagon-Like Peptide 1; Glucose; Glutamate Decarboxylase; Glyburide; Islets of Langerhans; Male; Mannoheptulose; Oxidation-Reduction; Peptide Fragments; Protein Precursors; Rats; Rats, Wistar; Verapamil | 2002 |
Differential activation mechanisms of Erk-1/2 and p70(S6K) by glucose in pancreatic beta-cells.
Topics: Animals; Calcium; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glyburide; Humans; Islets of Langerhans; Isoquinolines; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Peptide Fragments; Phosphorylation; Proto-Oncogene Proteins c-raf; Rats; Rats, Sprague-Dawley; Ribosomal Protein S6 Kinases, 70-kDa; Sulfonamides; Verapamil | 2003 |
A novel glucose-sensing mechanism contributing to glucagon-like peptide-1 secretion from the GLUTag cell line.
Topics: Animals; Carbohydrates; Cell Line; Fructose; Gene Expression Regulation; Glucagon; Glucagon-Like Peptide 1; Glucose; Glyburide; Hypoglycemic Agents; Islets of Langerhans; Kinetics; Mannitol; Mice; Monosaccharide Transport Proteins; Peptide Fragments; Phlorhizin; Protein Precursors | 2003 |
Evidence for hypothalamic K+(ATP) channels in the modulation of glucose homeostasis.
Topics: Animals; Blood Glucose; Carbamates; Chromatography, High Pressure Liquid; Epinephrine; Glucagon; Glyburide; Homeostasis; Hypoglycemic Agents; Hypothalamus; Male; Norepinephrine; Piperidines; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Sprague-Dawley | 2004 |
Reduced serum dipeptidyl peptidase-IV after metformin and pioglitazone treatments.
Topics: Aging; Animals; Blood Glucose; Cell Membrane; Dipeptidyl Peptidase 4; Glucagon; Glucagon-Like Peptide 1; Glucose Tolerance Test; Glyburide; Hemoglobins; Hypoglycemic Agents; Insulin; Kidney; Liver; Male; Metformin; Peptide Fragments; Pioglitazone; PPAR gamma; Protein Precursors; Rats; Rats, Zucker; Thiazolidinediones | 2004 |
Intragranular targeting of syncollin, but not a syncollinGFP chimera, inhibits regulated insulin exocytosis in pancreatic beta-cells.
Topics: Animals; Carrier Proteins; Cell Line; Exocytosis; Glucagon; Glucagon-Like Peptide 1; Glucose; Glyburide; Green Fluorescent Proteins; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Membrane Proteins; Microscopy, Confocal; Microscopy, Fluorescence; Peptide Fragments; Protein Precursors; Rats; Rats, Sprague-Dawley; Recombinant Fusion Proteins; Stimulation, Chemical | 2005 |
Anti-diabetic activity of SMK001, a poly herbal formula in streptozotocin induced diabetic rats: therapeutic study.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Female; Glucagon; Glyburide; Glycosuria; Hypoglycemic Agents; Immunohistochemistry; Insulin; Organ Size; Pancreas; Plant Extracts; Rats; Rats, Sprague-Dawley | 2006 |
Cholinergic regulation of fuel-induced hormone secretion and respiration of SUR1-/- mouse islets.
Topics: Acetylcholine; Acetylcholinesterase; Amino Acids; Animals; ATP-Binding Cassette Transporters; Calcium; Cell Respiration; Cholinergic Fibers; Gene Expression; Glucagon; Glucose; Glucose Transporter Type 2; Glyburide; Hormones; Insulin; Insulin Secretion; Islets of Langerhans; Kv1.3 Potassium Channel; Large-Conductance Calcium-Activated Potassium Channel beta Subunits; Mice; Mice, Inbred C57BL; Mice, Knockout; Multidrug Resistance-Associated Proteins; Oxygen Consumption; Potassium Channels, Inwardly Rectifying; Receptors, Drug; RNA, Messenger; Sulfonylurea Receptors | 2006 |
Foxa1-deficient mice exhibit impaired insulin secretion due to uncoupled oxidative phosphorylation.
Topics: Animals; Glucagon; Glucose; Glyburide; Hepatocyte Nuclear Factor 3-alpha; Insulin; Insulin Secretion; Insulin-Secreting Cells; Ion Channels; Islets of Langerhans; Mice; Mitochondrial Proteins; Oxidative Phosphorylation; Uncoupling Protein 2 | 2006 |
Octreotide in children with hypoglycaemia due to sulfonylurea ingestion.
Topics: Child, Preschool; Female; Glucagon; Glucose; Glyburide; Humans; Hypoglycemia; Hypoglycemic Agents; Infant; Infusions, Intravenous; Male; Native Hawaiian or Other Pacific Islander; Northern Territory; Octreotide; Sulfonylurea Compounds | 2008 |
Sitagliptin lowers glucagon and improves glucose tolerance in prediabetic obese SHROB rats.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Disease Models, Animal; Feeding Behavior; Glucagon; Glucagon-Like Peptide 1; Glyburide; Hypoglycemic Agents; Insulin; Insulin Secretion; Pyrazines; Rats; Sitagliptin Phosphate; Triazoles | 2011 |
Contribution of systemic inflammation to permanence of K
Topics: Animals; Blood Glucose; Cytokines; Diabetes Mellitus; Glucagon; Glucagon-Like Peptide 1; Glyburide; Inflammation; Insulin; Insulin Resistance; Leptin; Mice; Mice, Transgenic; Mutation; Potassium Channels, Inwardly Rectifying | 2018 |
E4orf1-induced reduction in endogenous insulin level is independent of pancreas endocrine function.
Topics: Adenovirus E4 Proteins; Animals; Blood Glucose; Doxycycline; Glucagon; Glucose; Glyburide; Hyperinsulinism; Insulin; Insulin-Secreting Cells; Islets of Langerhans; Mice; Mice, Inbred C57BL; Obesity; Phenylephrine | 2022 |
Reducing hyperglucagonaemia in type 2 diabetes using low-dose glibenclamide: Results of the LEGEND-A pilot study.
Topics: Blood Glucose; Diabetes Mellitus, Type 2; Glucagon; Glyburide; Humans; Hypoglycemic Agents; Insulin; Pilot Projects | 2022 |