Page last updated: 2024-09-04

glucagon and glucagon-like peptide 2

glucagon has been researched along with glucagon-like peptide 2 in 101 studies

Compound Research Comparison

Studies (glucagon)	Trials (glucagon)	Recent Studies (post-2010) (glucagon)	Studies (glucagon-like peptide 2)	Trials (glucagon-like peptide 2)	Recent Studies (post-2010) (glucagon-like peptide 2)
26,039	1,498	3,054	798	64	442

Research

Studies (101)

Timeframe	Studies, this research(%)	All Research%
pre-1990	6 (5.94)	18.7374
1990's	20 (19.80)	18.2507
2000's	51 (50.50)	29.6817
2010's	14 (13.86)	24.3611
2020's	10 (9.90)	2.80

Authors

Authors	Studies
Alarcón, C; Castilla, C; López-Novoa, JM; Pintado, J; Ruiz-Grande, C; Valverde, I	1
Gespach, CP; Hansen, AB; Holst, JJ; Rosselin, GE	1
Andrews, PC; Mommsen, TP; Plisetskaya, EM	1
Holst, JJ; Kirkegaard, P; Orskov, C; Poulsen, SS	1
Baldissera, FG; Holst, JJ; Knuhtsen, S; Nielsen, OV; Orskov, C; Poulsen, SS	1
Bishop, AE; Bloom, SR; Polak, JM; Sikri, KL; Uttenthal, LO; Varndell, IM	1
Gurd, RS; Hoosein, NM	1
Irwin, DM; Wong, J	1
Eng, J; Raufman, JP; Singh, G	1
Barragán, JM; Blázquez, E; Rodríguez, RE	1
Hanafusa, T; Kuwajima, M; Matsumura, T; Matsuzawa, Y; Miki, H; Mineo, I; Miyagawa, J; Nakajima, H; Namba, M; Nishimura, T	1
Asa, SL; Brubaker, PL; Drucker, DJ; Erlich, P	1
Cheeseman, CI; Tsang, R	1
Holst, JJ	3
Brubaker, PL; Cooper, S; Crivici, A; DeForest, L; Drucker, DJ; Hill, M; Shi, Q; Sumner-Smith, M; Tavares, W	1
Brubaker, PL; Dhanvantari, S; Drucker, DJ; Fischer, KD	1
Göke, B; Göke, R; McGregor, GP	1
Drucker, DJ	5
Brubaker, PL; Dhanvantari, S	1
Abdel-Wahab, YH; Conlon, JM; Nielsen, PF; O'Harte, FP; Whittaker, J	1
McBurney, MI; Tappenden, KA	1
Hartmann, B; Hilsted, L; Holst, JJ; Wettergren, A; Wøjdemann, M	1
Asa, SL; Drucker, DJ; Hill, ME	1
Drucker, DJ; Grinstein, S; Klip, A; Munroe, D; Somwar, R; Wang, F; Yusta, B	1
Dunphy, JL; Fuller, PJ; Justice, FA; Taylor, RG	1
Huner, O; Irwin, DM; Youson, JH	1
Adelhorst, K; Hartmann, B; Holst, JJ; Johnsen, AH; Orskov, C; Thim, L	1
Bisgaard, T; Hansen, L; Hartmann, B; Holst, JJ; Jørgensen, PN; Mineo, H	1
Irwin, DM; Sivarajah, P	1
Bregenholt, S; Claesson, MH; Hartmann, B; Hoist, JJ; Schmidt, PT	1
Larsen, PJ; Rømer, J; Tang-Christensen, M; Thulesen, J; Vrang, N	1
Hansen, BS; Hartmann, B; Holst, JJ; Jeppesen, PB; Mortensen, PB; Poulsen, SS; Thulesen, J	1
Brubaker, PL; Dableh, L; Drucker, DJ; Iliopoulos, I; Lovshin, J; Migirdicyan, A; Yusta, B	1
Arnold, R; Barth, P; Byrne, MM; Göke, B; McGregor, GP; Rothmund, M	1
Irwin, DM	2
Adatia, F; Baggio, L; Boushey, RP; Drucker, DJ; Liu, Y; Lovshin, J; Nian, M; Saleh, J; Scrocchi, L; Yusta, B	1
Balaspiri, L; Hirotani, Y; Kurokawa, K; Yamamoto, K; Yanaihara, C; Yanaihara, N	1
Bloom, SR; Brynes, AE; Ghatei, MA; Goodlad, RA; Jordinson, M; Mandir, N; Taheri, S	1
Djuricin, G; Gattuso, P; Kouris, GJ; Liu, Q; Nathan, C; Prinz, RA; Rossi, H; Weinstein, RA	1
Fukushima, K; Funayama, Y; Hashimoto, A; Jin, XL; Matsuno, S; Naito, H; Sasaki, I; Shibata, C; Ueno, T	1
Chow, BK; Yeung, CM	1
Burrin, DG; Petersen, YM; Sangild, PT	1
Drucker, DJ; Gu, J; Irwin, DM; Nian, M	1
Graff, J; Haderslev, KV; Hansen, BS; Hartmann, B; Holst, JJ; Jeppesen, PB; Madsen, JL; Mortensen, PB; Poulsen, SS; Sorensen, HA; Staun, M; Thulesen, J; Tofteng, F	1
Bjerre-Knudsen, L; Hay-Schmidt, A; Jensen, PB; Kristensen, P; Larsen, PJ; Rømer, J; Tang-Christensen, M; Vrang, N	1
Bozkurt, A; Hellström, PM; Holst, JJ; Näslund, E	1
De Meester, I; Lambeir, AM; Proost, P; Scharpé, S	1
Conlon, JM; Johansson, A; Kikuyama, S; Kim, JB	1
Dahly, EM; Gillingham, MB; Guo, Z; Holst, JJ; Murali, SG; Nelson, DW; Ney, DM	1
Astrup, A; Feldt-Rasmussen, U; Holst, JJ; Mersebach, H; Svendsen, OL	1
Brubaker, PL; Drucker, DJ	2
Larsen, PJ; Tang-Christensen, M; Vrang, N	1
Deacon, CF; Holst, JJ; Steiner, DF; Ugleholdt, R; Zhu, X; Ørskov, C	1
Anini, Y; Brubaker, PL	1
Hansen, L; Hartmann, B; Holst, JJ; Mineo, H	1
Thulesen, J	1
Holst, JJ; Mortensen, D; Nagell, CF; Pedersen, JF; Wettergren, A	1
Ansorge, N; Bulut, K; Felderbauer, P; Gallwitz, B; Hoffmann, P; Meier, JJ; Schmidt, WE; Schmitz, F	1
Baggio, LL; Brown, TJ; Drucker, DJ; Huang, Q	1
Carroll, R; Dey, A; Lipkind, GM; Norrbom, C; Rouillé, Y; Stein, J; Steiner, DF; Zhang, C	1
Baggio, LL; Drucker, DJ	1
Clandinin, MT; Drozdowski, L; Iordache, C; Thomson, AB; Todd, Z; Wild, G	1
Dworzecki, T; Otto Buczkowska, E	1
Brubaker, PL; Drucker, DJ; Estall, JL; Izzo, A; Shin, ED	1
Cani, PD; Delzenne, NM; Maton, N; Neyrinck, AM	1
Drucker, DJ; Sinclair, EM	1
Ardill, JE; Caddy, GR; Caldwell, CM; Fillmore, D; Gardiner, KR; McKibben, BM; Watson, PR	1
Bulut, K; Gallwitz, B; Goetze, O; Heinze, K; Holst, JJ; Meier, JJ; Nauck, MA; Pott, A; Schmidt, WE	1
Banasch, M; Bulut, K; Hagemann, D; Holst, JJ; Meier, JJ; Schmidt, WE; Schrader, H	1
de Heer, J; Holst, JJ; Orskov, C; Pedersen, J	1
Astrup, A; Due, A; Heding, A; Holst, JJ; Larsen, TM; Sloth, B	1
Baggio, LL; Bahrami, J; Drucker, DJ; Li, K; Longuet, C	1
Aaboe, K; Christensen, M; Holst, JJ; Knop, FK; Krarup, T; Madsbad, S; Vilsbøll, T	1
Bagger, JI; Holst, JJ; Knop, FK; Lund, A; Vilsbøll, T	1
Almdal, T; Bojsen-Møller, KN; Clausen, TR; Dirksen, C; Hansen, DL; Holst, JJ; Hvolris, LE; Jacobsen, SH; Jørgensen, NB; Kielgast, U; Madsbad, S; Naver, LS; Olesen, SC; Rehfeld, JF; Worm, D; Wulff, BS	1
Bednářová, A; Kodrík, D; Krishnan, N	1
Hare, KJ; Holst, JJ; Knop, FK; Martens, P; Rehfeld, JF; Sonne, DP; Vilsbøll, T	1
Dhanvantari, S; Guizzetti, L; McGirr, R	1
Ahmed, L; Bantle, JP; Bessler, M; Billington, CJ; Connett, JE; Ikramuddin, S; Inabnet, WB; Korner, J; Nguyen, KT; Thomas, A; Vella, A; Wang, Q	1
Bindels, LB; Burkart, V; Hartmann, B; Henrich, B; Holst, JJ; Hwang, JH; Kolb, H; MacKenzie, C; Martinez, I; Nowotny, B; Nowotny, P; Pacini, G; Roden, M; Schloot, NC; Simon, MC; Stehle, P; Strassburger, K; Walter, J; Zivehe, F	1
Cho, YM; Lee, HJ; Oh, TJ	1
Honda, K	1
Akimoto, T; Horiguchi, M; Nagai, M; Nakamura, R; Nakao, Y; Oka, JI; Sanai, E; Sasaki-Hamada, S; Yamashita, C	1
Charron, MJ; Drucker, DJ; Matthews, D; Patel, A; Seeley, RJ; Yusta, B	1
Berner-Hansen, M; Larsen, BD; Skarbaliene, J; Steensberg, A	1
Flatt, PR; Gault, VA; Irwin, N; Lafferty, RA; O'Harte, FPM	1
Bräuner-Osborne, H; Hauser, AS; Lindquist, P; Madsen, JS; Rosenkilde, MM	1
Bouvard, B; Legrand, E; Mabilleau, G; Mieczkowska, A	1
Neill, U	1
Andersen, DB; Holst, JJ	1
Brubaker, PL	1
Akita, T; Kimura, R; Nagai, M; Oda, Y; Oka, JI; Shimamura, M; Tezuka, A; Washizu, K; Yamashita, C	1
Argyrakopoulou, G; Bontozoglou, N; Kalra, B; Kokkinos, A; Konstantinidou, SK; Kouvari, M; Kumar, A; Kumar, M; Kyriakopoulou, K; Mantzoros, CS; Simati, S; Stefanakis, K	1

Reviews

25 review(s) available for glucagon and glucagon-like peptide 2

Article	Year
Enteroglucagon. Annual review of physiology, 1997, Volume: 59 Topics: Animals; Glicentin; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Humans; Intestinal Mucosa; Oxyntomodulin; Peptide Fragments; Peptides; Proglucagon; Protein Precursors	1997
Biological actions of glucagon-like peptide(GLP)-2 revealed--how pluripotential is the glucagon gene? Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 1998, Volume: 106, Issue:1 Topics: Cell Division; Glucagon; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Humans; Peptides	1998
Glucagon-like peptides. Diabetes, 1998, Volume: 47, Issue:2 Topics: Amino Acid Sequence; Animals; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucagon-Like Peptide-1 Receptor; Humans; Molecular Sequence Data; Peptide Fragments; Peptides; Protein Precursors; Receptors, Glucagon	1998
Gut hormones as pharmaceuticals. From enteroglucagon to GLP-1 and GLP-2. Regulatory peptides, 2000, Sep-25, Volume: 93, Issue:1-3 Topics: Animals; Digestive System; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Humans; Peptide Fragments; Peptides; Protein Precursors	2000
Minireview: the glucagon-like peptides. Endocrinology, 2001, Volume: 142, Issue:2 Topics: Animals; Central Nervous System; Diabetes Mellitus; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Humans; Intestinal Diseases; Intestines; Pancreas; Peptide Fragments; Peptides; Protein Precursors	2001
Molecular evolution of proglucagon. Regulatory peptides, 2001, Apr-02, Volume: 98, Issue:1-2 Topics: Animals; Evolution, Molecular; Genes; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Humans; Peptide Fragments; Peptides; Phylogeny; Proglucagon; Protein Precursors	2001
New developments in the biology of the glucagon-like peptides GLP-1 and GLP-2. Annals of the New York Academy of Sciences, 2000, Volume: 921 Topics: Animals; Diabetes Mellitus; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucagon-Like Peptide-1 Receptor; In Vitro Techniques; Intestinal Diseases; Intestinal Mucosa; Islets of Langerhans; Mice; Mice, Knockout; Peptide Fragments; Peptides; Protein Precursors; Receptors, Glucagon; Signal Transduction	2000
Gut adaptation and the glucagon-like peptides. Gut, 2002, Volume: 50, Issue:3 Topics: Adaptation, Physiological; Animals; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Humans; Intestinal Diseases; Intestines; Mice; Peptide Fragments; Peptides; Protein Precursors; Rats; Short Bowel Syndrome	2002
Ups and downs for neuropeptides in body weight homeostasis: pharmacological potential of cocaine amphetamine regulated transcript and pre-proglucagon-derived peptides. European journal of pharmacology, 2002, Apr-12, Volume: 440, Issue:2-3 Topics: Adipose Tissue; Animals; Body Weight; Eating; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Homeostasis; Humans; Hypothalamus; Nerve Tissue Proteins; Neurons; Neuropeptides; Peptide Fragments; Peptides; Protein Precursors	2002
Structure-function of the glucagon receptor family of G protein-coupled receptors: the glucagon, GIP, GLP-1, and GLP-2 receptors. Receptors & channels, 2002, Volume: 8, Issue:3-4 Topics: Alternative Splicing; Animals; Cloning, Molecular; Gastric Inhibitory Polypeptide; Genetic Diseases, Inborn; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucagon-Like Peptide-1 Receptor; Humans; Peptide Fragments; Peptides; Protein Precursors; Receptors, Gastrointestinal Hormone; Receptors, Glucagon; Structure-Activity Relationship	2002
Glucagon-like peptides: regulators of cell proliferation, differentiation, and apoptosis. Molecular endocrinology (Baltimore, Md.), 2003, Volume: 17, Issue:2 Topics: Animals; Apoptosis; Cell Differentiation; Cell Division; Exocrine Glands; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucagon-Like Peptide-1 Receptor; Humans; Intestines; Islets of Langerhans; Peptide Fragments; Peptide Hormones; Peptides; Protein Precursors; Receptors, Glucagon; Signal Transduction	2003
Central pre-proglucagon derived peptides: opportunities for treatment of obesity. Current pharmaceutical design, 2003, Volume: 9, Issue:17 Topics: Animals; Behavior, Animal; Central Nervous System; Eating; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Humans; Obesity; Oxyntomodulin; Peptide Fragments; Peptides; Proglucagon; Protein Precursors; Receptors, Glucagon	2003
Direct and indirect mechanisms regulating secretion of glucagon-like peptide-1 and glucagon-like peptide-2. Canadian journal of physiology and pharmacology, 2003, Volume: 81, Issue:11 Topics: Animals; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Humans; Intestinal Mucosa; Peptide Fragments; Peptides; Protein Precursors; Vagus Nerve	2003
Glucagon-like peptide 2 (GLP-2), an intestinotrophic mediator. Current protein & peptide science, 2004, Volume: 5, Issue:1 Topics: Amino Acid Sequence; Animals; Gastrointestinal Hormones; Glicentin; Glucagon; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Humans; Intestines; Molecular Sequence Data; Peptide Fragments; Peptides; Protein Precursors; Rats; Receptors, Glucagon	2004
Minireview: Glucagon-like peptides regulate cell proliferation and apoptosis in the pancreas, gut, and central nervous system. Endocrinology, 2004, Volume: 145, Issue:6 Topics: Animals; Apoptosis; Cell Division; Central Nervous System; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Intestines; Pancreas; Peptide Fragments; Peptides; Protein Precursors	2004
Clinical endocrinology and metabolism. Glucagon-like peptide-1 and glucagon-like peptide-2. Best practice & research. Clinical endocrinology & metabolism, 2004, Volume: 18, Issue:4 Topics: Animals; Cardiovascular Physiological Phenomena; Diabetes Mellitus, Type 2; Feeding Behavior; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucose; Humans; Nervous System Physiological Phenomena; Peptide Fragments; Peptides; Protein Precursors	2004
[Glucagon-like peptides--synthesis, biological actions and some clinical implications]. Przeglad lekarski, 2004, Volume: 61, Issue:9 Topics: Animals; Blood Glucose; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Humans; Intestinal Diseases; Intestinal Mucosa; Islets of Langerhans; Peptide Fragments; Peptides; Pilot Projects; Protein Precursors; Short Bowel Syndrome; Signal Transduction	2004
Proglucagon-derived peptides: mechanisms of action and therapeutic potential. Physiology (Bethesda, Md.), 2005, Volume: 20 Topics: Animals; Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Disease; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Humans; Intestinal Diseases; Peptide Fragments; Peptides; Proglucagon; Protease Inhibitors; Protein Precursors; Receptors, Glucagon	2005
Biologic actions and therapeutic potential of the proglucagon-derived peptides. Nature clinical practice. Endocrinology & metabolism, 2005, Volume: 1, Issue:1 Topics: Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Humans; Intestinal Mucosa; Proglucagon	2005
Glucagon and glucagon-like peptides 1 and 2. Results and problems in cell differentiation, 2010, Volume: 50 Topics: Animals; Brain Stem; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Humans; Models, Biological; Neurons; Peptide Fragments; Peptides; Proprotein Convertase 1; Proprotein Convertase 2; Protein Processing, Post-Translational	2010
Unique roles of glucagon and glucagon-like peptides: Parallels in understanding the functions of adipokinetic hormones in stress responses in insects. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 2013, Volume: 164, Issue:1 Topics: Animals; Brain; Cell Membrane; Cyclic AMP; Energy Metabolism; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Humans; Insect Hormones; Insecta; Neurons; Oligopeptides; Oxidative Stress; Pyrrolidonecarboxylic Acid; Reactive Oxygen Species	2013
Glucagon-related peptides and the regulation of food intake in chickens. Animal science journal = Nihon chikusan Gakkaiho, 2016, Volume: 87, Issue:9 Topics: Animals; Brain; Chickens; Eating; Energy Metabolism; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucose; Homeostasis; Intestinal Mucosa; Neurotransmitter Agents; Organ Specificity; Oxyntomodulin; Pancreas	2016
Proglucagon-Derived Peptides as Therapeutics. Frontiers in endocrinology, 2021, Volume: 12 Topics: Diabetes Mellitus, Type 2; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Humans; Proglucagon	2021
Peptides in the regulation of glucagon secretion. Peptides, 2022, Volume: 148 Topics: Animals; Blood Glucose; Calcitonin; Gastric Inhibitory Polypeptide; Ghrelin; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Humans; Insulin; Islet Amyloid Polypeptide; Neurotensin; Oxyntomodulin; Oxytocin; Pancreas; Pancreatic Polypeptide; Somatostatin; Urocortins; Vasopressins	2022
The Molecular Determinants of Glucagon-like Peptide Secretion by the Intestinal L cell. Endocrinology, 2022, 10-11, Volume: 163, Issue:11 Topics: Diabetes Mellitus, Type 2; Enteroendocrine Cells; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Humans; Peptide Fragments; Peptides; Secretagogues	2022

Trials

6 trial(s) available for glucagon and glucagon-like peptide 2

Article	Year
Inhibition of sham feeding-stimulated human gastric acid secretion by glucagon-like peptide-2. The Journal of clinical endocrinology and metabolism, 1999, Volume: 84, Issue:7 Topics: Cholecystokinin; Gastric Acid; Gastrins; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Humans; Infusions, Intravenous; Peptide Fragments; Peptides; Protein Precursors; Secretin	1999
Glucagon-like peptide-2 inhibits antral emptying in man, but is not as potent as glucagon-like peptide-1. Scandinavian journal of gastroenterology, 2004, Volume: 39, Issue:4 Topics: Adult; Female; Gastric Emptying; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Humans; Hunger; Male; Middle Aged; Peptide Fragments; Peptides; Protein Precursors; Pyloric Antrum; Reference Values; Ultrasonography	2004
The effect of a high-MUFA, low-glycaemic index diet and a low-fat diet on appetite and glucose metabolism during a 6-month weight maintenance period. The British journal of nutrition, 2009, Volume: 101, Issue:12 Topics: Adult; Analysis of Variance; Appetite Regulation; Area Under Curve; Blood Glucose; Body Mass Index; Body Weight; Diet, Fat-Restricted; Energy Intake; Fatty Acids, Monounsaturated; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glycemic Index; Humans; Insulin; Male; Obesity; Pancreatic Polypeptide; Peptide YY; Time Factors; Triglycerides	2009
Postprandial gut hormone responses and glucose metabolism in cholecystectomized patients. American journal of physiology. Gastrointestinal and liver physiology, 2013, Feb-15, Volume: 304, Issue:4 Topics: Adult; Aged; Bile Acids and Salts; Blood Glucose; C-Peptide; Cholecystectomy; Female; Gastric Emptying; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Humans; Insulin; Insulin Secretion; Male; Middle Aged; Postprandial Period	2013
Preserved Insulin Secretory Capacity and Weight Loss Are the Predominant Predictors of Glycemic Control in Patients With Type 2 Diabetes Randomized to Roux-en-Y Gastric Bypass. Diabetes, 2015, Volume: 64, Issue:9 Topics: Adiponectin; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Female; Gastric Bypass; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Male; Middle Aged; Obesity; Treatment Outcome; Weight Loss	2015
Intake of Lactobacillus reuteri improves incretin and insulin secretion in glucose-tolerant humans: a proof of concept. Diabetes care, 2015, Volume: 38, Issue:10 Topics: Adult; Aged; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucose; Glucose Clamp Technique; Glucose Tolerance Test; Humans; Incretins; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Limosilactobacillus reuteri; Male; Middle Aged; Obesity; Oxidative Stress; Pilot Projects; Probiotics; Prospective Studies; Protein Precursors	2015

Other Studies

70 other study(ies) available for glucagon and glucagon-like peptide 2

Article	Year
Renal catabolism of human glucagon-like peptides 1 and 2. Canadian journal of physiology and pharmacology, 1990, Volume: 68, Issue:12 Topics: Animals; Chromatography, High Pressure Liquid; Glomerular Filtration Rate; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Humans; In Vitro Techniques; Inulin; Iodine Radioisotopes; Kidney; Nephrectomy; Peptide Fragments; Peptides; Perfusion; Protein Precursors; Rats; Rats, Inbred Strains	1990
Effect of truncated glucagon-like peptide 1 on cAMP in rat gastric glands and HGT-1 human gastric cancer cells. FEBS letters, 1988, Aug-15, Volume: 236, Issue:1 Topics: Animals; Cyclic AMP; Gastric Mucosa; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucagon-Like Peptide-1 Receptor; Humans; Male; Peptides; Protein Precursors; Rats; Receptors, Cell Surface; Receptors, Glucagon; Stomach Neoplasms; Tumor Cells, Cultured	1988
Glucagon-like peptides activate hepatic gluconeogenesis. FEBS letters, 1987, Jul-13, Volume: 219, Issue:1 Topics: Animals; Carbon Dioxide; Catfishes; Fishes; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Gluconeogenesis; In Vitro Techniques; Lactates; Liver; Peptides; Salmon; Trout	1987
Pancreatic and intestinal processing of proglucagon in man. Diabetologia, 1987, Volume: 30, Issue:11 Topics: Adult; Amino Acid Sequence; Chromatography, Gel; Chromatography, High Pressure Liquid; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Humans; Ileum; Intestine, Small; Pancreas; Pancreatic Hormones; Peptides; Proglucagon; Protein Precursors; Radioimmunoassay	1987
Glucagon-like peptides GLP-1 and GLP-2, predicted products of the glucagon gene, are secreted separately from pig small intestine but not pancreas. Endocrinology, 1986, Volume: 119, Issue:4 Topics: Animals; Arginine; Gastrin-Releasing Peptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucose; Histocytochemistry; Immunoenzyme Techniques; Intestine, Small; Pancreas; Peptides; Proglucagon; Protein Precursors; Swine	1986
Localization of glucagon-like peptide (GLP) immunoreactants in human gut and pancreas using light and electron microscopic immunocytochemistry. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 1985, Volume: 33, Issue:10 Topics: Colon; Cytoplasmic Granules; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Gold; Histocytochemistry; Humans; Immunoenzyme Techniques; Immunologic Techniques; Intestines; Microscopy, Electron; Pancreas; Peptides; Proglucagon; Protein Precursors; Rectum	1985
Human glucagon-like peptides 1 and 2 activate rat brain adenylate cyclase. FEBS letters, 1984, Dec-03, Volume: 178, Issue:1 Topics: Adenylyl Cyclases; Brain; Dose-Response Relationship, Drug; Enzyme Activation; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Humans; Peptides; Receptors, Cell Surface; Receptors, Glucagon	1984
Trout and chicken proglucagon: alternative splicing generates mRNA transcripts encoding glucagon-like peptide 2. Molecular endocrinology (Baltimore, Md.), 1995, Volume: 9, Issue:3 Topics: Alternative Splicing; Amino Acid Sequence; Animals; Base Sequence; Chickens; DNA, Complementary; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Intestines; Molecular Sequence Data; Oncorhynchus mykiss; Pancreas; Peptides; Proglucagon; Protein Precursors; RNA, Messenger	1995
Use of 125I-[Y39]exendin-4 to characterize exendin receptors on dispersed pancreatic acini and gastric chief cells from guinea pig. Regulatory peptides, 1994, Aug-31, Volume: 53, Issue:1 Topics: Amino Acid Sequence; Animals; Chromatography, High Pressure Liquid; Cyclic AMP; Exenatide; Gastric Mucosa; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Guinea Pigs; Iodine Radioisotopes; Male; Molecular Sequence Data; Pancreas; Peptides; Receptors, Gastrointestinal Hormone; Structure-Activity Relationship; Tyrosine; Venoms	1994
Changes in arterial blood pressure and heart rate induced by glucagon-like peptide-1-(7-36) amide in rats. The American journal of physiology, 1994, Volume: 266, Issue:3 Pt 1 Topics: Animals; Blood Pressure; Catecholamines; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Heart Rate; Male; Peptide Fragments; Peptides; Rats; Rats, Sprague-Dawley; Reserpine	1994
Glucagon-like peptide-1(7-36)amide enhances insulin-stimulated glucose uptake and decreases intracellular cAMP content in isolated rat adipocytes. Biochimica et biophysica acta, 1996, Jun-13, Volume: 1312, Issue:2 Topics: 1-Methyl-3-isobutylxanthine; Adipocytes; Animals; Colforsin; Cyclic AMP; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Glucose; Insulin; Male; Peptide Fragments; Peptides; Phosphodiesterase Inhibitors; Rats	1996
Induction of intestinal epithelial proliferation by glucagon-like peptide 2. Proceedings of the National Academy of Sciences of the United States of America, 1996, Jul-23, Volume: 93, Issue:15 Topics: Animals; Cell Division; Glicentin; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Glucagonoma; Ileum; Immunohistochemistry; Intestinal Mucosa; Jejunum; Kinetics; Mice; Mice, Nude; Organ Size; Pancreatic Hormones; Pancreatic Neoplasms; Peptide Fragments; Peptides; Proglucagon; Proliferating Cell Nuclear Antigen; Protein Precursors; Rats; Transplantation, Heterologous	1996
The effect of GIP and glucagon-like peptides on intestinal basolateral membrane hexose transport. The American journal of physiology, 1996, Volume: 271, Issue:3 Pt 1 Topics: Animals; Biological Transport; Cell Membrane; Cell Polarity; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Hexoses; Jejunum; Peptide Fragments; Peptides; Protein Precursors; Rats	1996
Regulation of the biological activity of glucagon-like peptide 2 in vivo by dipeptidyl peptidase IV. Nature biotechnology, 1997, Volume: 15, Issue:7 Topics: Animals; Biotechnology; Dipeptidyl Peptidase 4; Glucagon; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Humans; In Vitro Techniques; Intestine, Small; Mice; Peptides; Protein Engineering; Rats; Rats, Inbred F344; Recombinant Proteins	1997
Intestinal growth is associated with elevated levels of glucagon-like peptide 2 in diabetic rats. The American journal of physiology, 1997, Volume: 273, Issue:4 Topics: Animals; Diabetes Mellitus, Experimental; Gastrointestinal Hormones; Glicentin; Glucagon; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Insulin; Intestine, Small; Male; Organ Size; Organ Specificity; Oxyntomodulin; Peptide Fragments; Peptides; Proglucagon; Protein Precursors; Rats; Rats, Wistar; Time Factors	1997
Proglucagon processing in an islet cell line: effects of PC1 overexpression and PC2 depletion. Endocrinology, 1998, Volume: 139, Issue:4 Topics: Animals; Aspartic Acid Endopeptidases; Cell Line; DNA, Antisense; Gene Expression; Glicentin; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Islets of Langerhans; Mice; Oxyntomodulin; Peptide Fragments; Peptides; Proglucagon; Proprotein Convertase 1; Proprotein Convertase 2; Proprotein Convertases; Protein Precursors; RNA, Messenger; Subtilisins; Transfection	1998
Purification and characterization of insulin, glucagon, and two glucagon-like peptides with insulin-releasing activity from the pancreas of the toad, Bufo marinus. Endocrinology, 1998, Volume: 139, Issue:8 Topics: Amino Acid Sequence; Animals; Bufo marinus; Chromatography, High Pressure Liquid; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Humans; Insulin; Male; Molecular Sequence Data; Pancreas; Peptides; Receptor, Insulin; Sequence Homology	1998
Systemic short-chain fatty acids rapidly alter gastrointestinal structure, function, and expression of early response genes. Digestive diseases and sciences, 1998, Volume: 43, Issue:7 Topics: Animals; Blotting, Northern; Blotting, Western; Digestive System; Fatty Acids, Volatile; Gastrointestinal Hormones; Gene Expression; Glucagon; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Intestinal Mucosa; Male; Parenteral Nutrition, Total; Peptides; Proglucagon; Protein Precursors; Proto-Oncogenes; Random Allocation; Rats; Rats, Sprague-Dawley; RNA, Messenger	1998
Essential requirement for Pax6 in control of enteroendocrine proglucagon gene transcription. Molecular endocrinology (Baltimore, Md.), 1999, Volume: 13, Issue:9 Topics: Animals; Animals, Newborn; Blotting, Northern; Cell Line; DNA-Binding Proteins; Enteroendocrine Cells; Eye Proteins; Female; Gene Expression Regulation; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Homeodomain Proteins; Immunohistochemistry; Intestinal Mucosa; Intestines; Islets of Langerhans; Luciferases; Male; Mice; Mice, Mutant Strains; Mutation; Paired Box Transcription Factors; PAX6 Transcription Factor; Peptide Fragments; Peptides; Proglucagon; Promoter Regions, Genetic; Protein Binding; Protein Precursors; Recombinant Fusion Proteins; Repressor Proteins; RNA, Messenger; Tissue Distribution; Transcription, Genetic	1999
Identification of glucagon-like peptide-2 (GLP-2)-activated signaling pathways in baby hamster kidney fibroblasts expressing the rat GLP-2 receptor. The Journal of biological chemistry, 1999, Oct-22, Volume: 274, Issue:43 Topics: Animals; Cell Division; Cell Line; Cricetinae; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Fibroblasts; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucagon-Like Peptide-1 Receptor; Kidney; Luciferases; Mitogen-Activated Protein Kinases; Peptide Fragments; Peptides; Phosphorylation; Protein Precursors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Receptors, Glucagon; Recombinant Proteins; Signal Transduction; Transcription Factor AP-1; Transcription, Genetic; Transfection	1999
mRNA levels of dipeptidyl peptidase IV decrease during intestinal adaptation. The Journal of surgical research, 1999, Volume: 87, Issue:1 Topics: Adaptation, Physiological; Animals; Dipeptidyl Peptidase 4; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Intestines; Peptide Fragments; Peptides; Protein Precursors; Rats; Rats, Sprague-Dawley; RNA, Messenger	1999
Lamprey proglucagon and the origin of glucagon-like peptides. Molecular biology and evolution, 1999, Volume: 16, Issue:11 Topics: Amino Acid Sequence; Animals; Base Sequence; DNA, Complementary; Evolution, Molecular; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Humans; Lampreys; Molecular Sequence Data; Peptides; Proglucagon; Protein Precursors; RNA, Messenger; Sequence Homology, Amino Acid	1999
Structure, measurement, and secretion of human glucagon-like peptide-2. Peptides, 2000, Volume: 21, Issue:1 Topics: Chromatography, High Pressure Liquid; Glucagon; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Humans; Ileum; Mass Spectrometry; Pancreas; Peptide Fragments; Peptides; Proglucagon; Protein Precursors; Radioimmunoassay	2000
Somatostatin restrains the secretion of glucagon-like peptide-1 and -2 from isolated perfused porcine ileum. American journal of physiology. Endocrinology and metabolism, 2000, Volume: 278, Issue:6 Topics: Acetylcholine; Adrenergic alpha-Antagonists; Animals; Bombesin; Chromatography, Gel; Electric Stimulation; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Ileum; Peptide Fragments; Peptides; Phentolamine; Protein Precursors; Somatostatin; Swine	2000
Proglucagon cDNAs from the leopard frog, Rana pipiens, encode two GLP-1-like peptides. Molecular and cellular endocrinology, 2000, Apr-25, Volume: 162, Issue:1-2 Topics: Alternative Splicing; Amino Acid Sequence; Animals; Base Sequence; DNA Primers; DNA, Complementary; Evolution, Molecular; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Humans; Intestinal Mucosa; Molecular Sequence Data; Pancreas; Peptide Fragments; Peptides; Phylogeny; Proglucagon; Protein Precursors; Rana pipiens; RNA, Messenger; Sequence Homology, Amino Acid	2000
Deficiency of the intestinal growth factor, glucagon-like peptide 2, in the colon of SCID mice with inflammatory bowel disease induced by transplantation of CD4+ T cells. Scandinavian journal of gastroenterology, 2000, Volume: 35, Issue:5 Topics: Animals; CD4-Positive T-Lymphocytes; Colon; Disease Models, Animal; Glucagon; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Growth Substances; Inflammatory Bowel Diseases; Mice; Mice, SCID; Peptide Fragments	2000
The proglucagon-derived peptide, glucagon-like peptide-2, is a neurotransmitter involved in the regulation of food intake. Nature medicine, 2000, Volume: 6, Issue:7 Topics: Animals; Conditioning, Operant; Dorsomedial Hypothalamic Nucleus; Drinking; Eating; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Hypothalamus; Male; Neuropeptide Y; Neurotransmitter Agents; Peptide Fragments; Peptides; Proglucagon; Protein Precursors; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Taste	2000
Elevated plasma glucagon-like peptide 1 and 2 concentrations in ileum resected short bowel patients with a preserved colon. Gut, 2000, Volume: 47, Issue:3 Topics: Adaptation, Physiological; Adult; Aged; Area Under Curve; Case-Control Studies; Fasting; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Humans; Ileum; Male; Middle Aged; Peptide Fragments; Peptides; Postprandial Period; Protein Precursors; Radioimmunoassay; Short Bowel Syndrome	2000
Ontogeny of the glucagon-like peptide-2 receptor axis in the developing rat intestine. Endocrinology, 2000, Volume: 141, Issue:11 Topics: Animals; Animals, Newborn; Colon; Gene Expression; Glucagon; Glucagon-Like Peptide 2; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Intestinal Mucosa; Intestine, Small; Intestines; Organ Size; Peptides; Proglucagon; Protein Precursors; Rats; Rats, Wistar; Receptors, Glucagon; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stomach	2000
Intestinal proliferation and delayed intestinal transit in a patient with a GLP-1-, GLP-2- and PYY-producing neuroendocrine carcinoma. Digestion, 2001, Volume: 63, Issue:1 Topics: Cell Division; Gastrointestinal Transit; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Humans; Intestinal Mucosa; Intestine, Small; Jejunum; Liver Neoplasms; Male; Neoplasms, Unknown Primary; Neuroendocrine Tumors; Peptide Fragments; Peptides; Peritoneal Neoplasms; Protein Precursors	2001
Distinctive effects of glicentin, GLP-1 and GLP-2 on adaptive response to massive distal small intestine resection in rats. Annals of the New York Academy of Sciences, 2000, Volume: 921 Topics: Adaptation, Physiological; alpha-Glucosidases; Animals; DNA; Glicentin; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Growth Substances; Intestine, Small; Male; Organ Size; Peptide Fragments; Peptides; Protein Precursors; Proteins; Rats; Rats, Wistar; Sucrase; Time Factors	2000
Proglucagon-derived peptides in intestinal epithelial proliferation: glucagon-like peptide-2 is a major mediator of intestinal epithelial proliferation in rats. Digestive diseases and sciences, 2001, Volume: 46, Issue:6 Topics: Animals; Cell Division; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Intestinal Mucosa; Male; Peptides; Proglucagon; Protein Precursors; Rats; Rats, Wistar	2001
The effect of glucagon-like peptide 2 on intestinal permeability and bacterial translocation in acute necrotizing pancreatitis. American journal of surgery, 2001, Volume: 181, Issue:6 Topics: Analysis of Variance; Animals; Bacterial Translocation; Glucagon; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Ileum; Intestinal Mucosa; Jejunum; Male; Pancreatitis, Acute Necrotizing; Peptides; Permeability; Rats; Rats, Sprague-Dawley; Weight Loss	2001
Effect of glucagon, glicentin, glucagon-like peptide-1 and -2 on interdigestive gastroduodenal motility in dogs with a vagally denervated gastric pouch. Scandinavian journal of gastroenterology, 2001, Volume: 36, Issue:10 Topics: Animals; Dogs; Female; Gastrointestinal Motility; Glicentin; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Male; Peptide Fragments; Peptides; Protein Precursors; Stomach; Vagotomy	2001
Identification of a proglucagon cDNA from Rana tigrina rugulosa that encodes two GLP-1s and that is alternatively spliced in a tissue-specific manner. General and comparative endocrinology, 2001, Volume: 124, Issue:2 Topics: Alternative Splicing; Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; DNA, Complementary; Gene Expression Regulation; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Molecular Sequence Data; Peptide Fragments; Peptides; Proglucagon; Protein Precursors; Random Amplified Polymorphic DNA Technique; Ranidae; Reverse Transcriptase Polymerase Chain Reaction; Sequence Alignment; Sequence Analysis, DNA; Sequence Homology, Amino Acid	2001
GLP-2 has differential effects on small intestine growth and function in fetal and neonatal pigs. American journal of physiology. Regulatory, integrative and comparative physiology, 2001, Volume: 281, Issue:6 Topics: Animals; Animals, Newborn; Embryonic and Fetal Development; Female; Fetus; Gene Expression Regulation, Developmental; Glucagon; Glucagon-Like Peptide 2; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Humans; Intestine, Small; Peptides; Pregnancy; Rats; Receptors, Glucagon; Swine; Transcription, Genetic	2001
Human glucagon gene promoter sequences regulating tissue-specific versus nutrient-regulated gene expression. American journal of physiology. Regulatory, integrative and comparative physiology, 2002, Volume: 282, Issue:1 Topics: Animal Nutritional Physiological Phenomena; Animals; Diet; Dietary Fiber; DNA Primers; Gene Expression Regulation; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Human Growth Hormone; Humans; Insulin; Intestines; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Organ Size; Peptide Fragments; Peptides; Promoter Regions, Genetic; Protein Precursors; RNA, Messenger	2002
Short-term administration of glucagon-like peptide-2. Effects on bone mineral density and markers of bone turnover in short-bowel patients with no colon. Scandinavian journal of gastroenterology, 2002, Volume: 37, Issue:4 Topics: Absorptiometry, Photon; Adult; Alkaline Phosphatase; Amino Acids; Bone Density; Bone Diseases, Metabolic; Bone Remodeling; Calcium; Female; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Hormones; Humans; Intestinal Absorption; Male; Middle Aged; Osteocalcin; Osteoporosis; Parathyroid Hormone; Peptides; Pilot Projects; Short Bowel Syndrome; Vitamin D	2002
GLP-1 and GLP-2 act in concert to inhibit fasted, but not fed, small bowel motility in the rat. Regulatory peptides, 2002, Jul-15, Volume: 107, Issue:1-3 Topics: Animals; Blood Glucose; Drug Interactions; Eating; Electromyography; Fasting; Gastrointestinal Motility; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Injections, Intravenous; Insulin; Intestine, Small; Male; Peptide Fragments; Peptides; Protein Precursors; Rats; Rats, Sprague-Dawley	2002
A kinetic study of glucagon-like peptide-1 and glucagon-like peptide-2 truncation by dipeptidyl peptidase IV, in vitro. Biochemical pharmacology, 2002, Dec-15, Volume: 64, Issue:12 Topics: Amino Acid Sequence; Dipeptidyl Peptidase 4; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Humans; Kinetics; Molecular Sequence Data; Peptide Fragments; Peptides; Protein Precursors; Time Factors	2002
Comparative peptidomics of the endocrine pancreas: islet hormones from the clawed frog Xenopus laevis and the red-bellied newt Cynops pyrrhogaster. The Journal of endocrinology, 2002, Volume: 175, Issue:3 Topics: Amino Acid Sequence; Amphibians; Animals; Chromatography, High Pressure Liquid; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Insulin; Islets of Langerhans; Molecular Sequence Data; Pancreatic Hormones; Pancreatic Polypeptide; Peptide Fragments; Peptides; Protein Precursors; Salamandridae; Sequence Analysis, Protein; Spectrometry, Mass, Electrospray Ionization; Xenopus laevis	2002
Role of luminal nutrients and endogenous GLP-2 in intestinal adaptation to mid-small bowel resection. American journal of physiology. Gastrointestinal and liver physiology, 2003, Volume: 284, Issue:4 Topics: Adaptation, Physiological; Animals; Apoptosis; Body Weight; Cell Division; Eating; Enterocytes; Glucagon; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Ileum; Jejunum; Male; Parenteral Nutrition; Peptides; Proglucagon; Protein Precursors; Rats; Rats, Sprague-Dawley; Sucrase	2003
Comparisons of leptin, incretins and body composition in obese and lean patients with hypopituitarism and healthy individuals. Clinical endocrinology, 2003, Volume: 58, Issue:1 Topics: Adult; Anthropometry; Body Composition; Case-Control Studies; Cross-Sectional Studies; Fasting; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Human Growth Hormone; Humans; Hypopituitarism; Leptin; Lipids; Male; Middle Aged; Obesity; Peptide Fragments; Peptides; Thinness	2003
Impaired intestinal proglucagon processing in mice lacking prohormone convertase 1. Endocrinology, 2004, Volume: 145, Issue:3 Topics: Animals; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Immunohistochemistry; Intestines; Mice; Mice, Mutant Strains; Pancreas; Peptide Fragments; Peptides; Proglucagon; Proprotein Convertase 1; Protein Precursors	2004
Glucagon-like peptide-1 secretion is influenced by perfusate glucose concentration and by a feedback mechanism involving somatostatin in isolated perfused porcine ileum. Regulatory peptides, 2004, Apr-15, Volume: 118, Issue:1-2 Topics: Animals; Feedback, Physiological; Gastric Inhibitory Polypeptide; Gastrointestinal Motility; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucose; Ileum; In Vitro Techniques; Insulin; Peptide Fragments; Peptide YY; Peptides; Perfusion; Pressure; Protein Precursors; Somatostatin; Swine	2004
Glucagon-like peptide 2 improves intestinal wound healing through induction of epithelial cell migration in vitro-evidence for a TGF--beta-mediated effect. Regulatory peptides, 2004, Sep-15, Volume: 121, Issue:1-3 Topics: Animals; Antibodies, Monoclonal; Apoptosis; Cell Line; Cell Line, Tumor; Cell Movement; Cell Proliferation; Epithelial Cells; Flow Cytometry; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Humans; Intestines; Peptide Fragments; Peptides; Protein Precursors; Rats; Transforming Growth Factor beta; Transforming Growth Factor beta1; Wound Healing	2004
Oxyntomodulin and glucagon-like peptide-1 differentially regulate murine food intake and energy expenditure. Gastroenterology, 2004, Volume: 127, Issue:2 Topics: Amino Acid Sequence; Animals; Binding, Competitive; Brain; Cells, Cultured; Cricetinae; Dose-Response Relationship, Drug; Eating; Energy Metabolism; Exenatide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Injections, Intraperitoneal; Injections, Intraventricular; Iodine Radioisotopes; Mice; Mice, Inbred C57BL; Mice, Knockout; Molecular Sequence Data; Oxyntomodulin; Peptide Fragments; Peptides; Proglucagon; Protein Precursors; Proto-Oncogene Proteins c-fos; Rats; Receptors, G-Protein-Coupled; Receptors, Glucagon; Venoms	2004
Significance of prohormone convertase 2, PC2, mediated initial cleavage at the proglucagon interdomain site, Lys70-Arg71, to generate glucagon. Endocrinology, 2005, Volume: 146, Issue:2 Topics: Animals; Cricetinae; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Models, Molecular; Mutagenesis; Peptide Fragments; Peptides; Pituitary Gland; Proglucagon; Proprotein Convertase 2; Protein Precursors; Protein Structure, Tertiary	2005
Treatment of suckling rats with GLP-2 plus dexamethasone increases the ileal uptake of fatty acids in later life. American journal of physiology. Gastrointestinal and liver physiology, 2005, Volume: 288, Issue:1 Topics: Absorption; Animals; Animals, Newborn; Dexamethasone; Dietary Fats; Fatty Acids; Female; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Glucocorticoids; Ileum; Pancreatic Hormones; Peptides; Protein Precursors; Random Allocation; Rats; Rats, Sprague-Dawley; Weaning	2005
Mucosal adaptation to enteral nutrients is dependent on the physiologic actions of glucagon-like peptide-2 in mice. Gastroenterology, 2005, Volume: 128, Issue:5 Topics: Adaptation, Physiological; Amino Acid Sequence; Animals; Apoptosis; Body Weight; Cell Division; Cloning, Molecular; Drinking; Eating; Female; Gene Expression; Glucagon; Glucagon-Like Peptide 2; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Intestinal Mucosa; Intestine, Small; Male; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Organ Size; Peptide Fragments; Proglucagon; Protein Precursors; Rats; Rats, Wistar; Receptors, Glucagon	2005
Oligofructose promotes satiety in rats fed a high-fat diet: involvement of glucagon-like Peptide-1. Obesity research, 2005, Volume: 13, Issue:6 Topics: Animals; Body Weight; Dietary Fats; Dipeptidyl Peptidase 4; Eating; Ghrelin; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Intestinal Mucosa; Liver; Male; Obesity; Oligosaccharides; Peptide Fragments; Peptide Hormones; Peptides; Proglucagon; Protein Precursors; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Triglycerides	2005
Plasma concentrations of glucagon-like peptide-2 in adult patients with treated and untreated coeliac disease. European journal of gastroenterology & hepatology, 2006, Volume: 18, Issue:2 Topics: Adult; Celiac Disease; Female; Follow-Up Studies; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Glutens; Humans; Male; Middle Aged; Radioimmunoassay; Treatment Outcome	2006
Glucagon-like peptide 2 stimulates glucagon secretion, enhances lipid absorption, and inhibits gastric acid secretion in humans. Gastroenterology, 2006, Volume: 130, Issue:1 Topics: Adult; Fasting; Fatty Acids; Gastric Acid; Gastric Emptying; Glucagon; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Humans; Hypoglycemic Agents; Infusions, Intravenous; Insulin; Lipid Metabolism; Male; Placebos; Postprandial Period	2006
Glucagon-like peptide 2 inhibits ghrelin secretion in humans. Regulatory peptides, 2006, Dec-10, Volume: 137, Issue:3 Topics: Adult; Blood Glucose; C-Peptide; Ghrelin; Glucagon; Glucagon-Like Peptide 2; Humans; Infusions, Intravenous; Insulin; Kinetics; Male; Peptide Hormones	2006
The alpha cell expresses glucagon-like peptide-2 receptors and glucagon-like peptide-2 stimulates glucagon secretion from the rat pancreas. Diabetologia, 2007, Volume: 50, Issue:10 Topics: Animals; Deoxyribonucleases; DNA, Complementary; Gene Expression Regulation; Glucagon; Glucagon-Like Peptide 2; Glucagon-Like Peptide-2 Receptor; Humans; Male; Pancreas; Polymerase Chain Reaction; Proglucagon; Rats; Rats, Wistar; Receptors, Glucagon	2007
Glucagon-like peptide-2 receptor modulates islet adaptation to metabolic stress in the ob/ob mouse. Gastroenterology, 2010, Volume: 139, Issue:3 Topics: Adaptation, Physiological; Animals; Blood Glucose; Body Weight; Cell Proliferation; Diabetes Mellitus, Experimental; Disease Models, Animal; Glucagon; Glucagon-Like Peptide 2; Glucagon-Like Peptide-2 Receptor; Glucose Intolerance; Glucose Tolerance Test; Hypoglycemia; Insulin; Islets of Langerhans; Mice; Mice, Inbred C57BL; Mice, Knockout; Obesity; Receptors, Glucagon; Signal Transduction; Stress, Physiological; Time Factors	2010
Glucagon-like peptide-2, but not glucose-dependent insulinotropic polypeptide, stimulates glucagon release in patients with type 1 diabetes. Regulatory peptides, 2010, Aug-09, Volume: 163, Issue:1-3 Topics: Adult; Diabetes Mellitus, Type 1; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 2; Humans; Time Factors; Young Adult	2010
The separate and combined impact of the intestinal hormones, GIP, GLP-1, and GLP-2, on glucagon secretion in type 2 diabetes. American journal of physiology. Endocrinology and metabolism, 2011, Volume: 300, Issue:6 Topics: Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucose Tolerance Test; Humans; Incretins; Insulin; Insulin-Secreting Cells; Male; Middle Aged; Peptides	2011
Changes in gastrointestinal hormone responses, insulin sensitivity, and beta-cell function within 2 weeks after gastric bypass in non-diabetic subjects. Obesity surgery, 2012, Volume: 22, Issue:7 Topics: Adult; Appetite; C-Peptide; Cholecystokinin; Confounding Factors, Epidemiologic; Female; Gastric Bypass; Gastric Inhibitory Polypeptide; Gastrins; Gastrointestinal Hormones; Ghrelin; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Islet Amyloid Polypeptide; Leptin; Male; Middle Aged; Obesity, Morbid; Pancreatic Polypeptide; Peptide YY; Postprandial Period; Somatostatin; Time Factors; Weight Loss	2012
Two dipolar α-helices within hormone-encoding regions of proglucagon are sorting signals to the regulated secretory pathway. The Journal of biological chemistry, 2014, May-23, Volume: 289, Issue:21 Topics: Amino Acid Sequence; Animals; Blotting, Western; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Mesocricetus; Microscopy, Confocal; Models, Molecular; Molecular Sequence Data; Open Reading Frames; PC12 Cells; Peptides; Proglucagon; Protein Processing, Post-Translational; Protein Structure, Secondary; Protein Transport; Rats; Secretory Pathway; Secretory Vesicles; Signal Transduction	2014
Ileal Transposition Decreases Plasma Lipopolysaccharide Levels in Association with Increased L Cell Secretion in Non-obese Non-diabetic Rats. Obesity surgery, 2016, Volume: 26, Issue:6 Topics: Animals; Blood Glucose; Body Weight; Drinking; Eating; Enteroendocrine Cells; Gastric Inhibitory Polypeptide; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucose Tolerance Test; Ileum; Insulin Resistance; Lipopolysaccharides; Male; Obesity, Morbid; Peptide YY; Rats, Sprague-Dawley	2016
Antidepressant-like effects exerted by the intranasal administration of a glucagon-like peptide-2 derivative containing cell-penetrating peptides and a penetration-accelerating sequence in mice. Peptides, 2017, Volume: 87 Topics: Administration, Intranasal; Animals; Antidepressive Agents; Brain; Cell-Penetrating Peptides; Depressive Disorder, Major; Disease Models, Animal; Glucagon; Glucagon-Like Peptide 2; Mice	2017
GLP-2 receptor signaling controls circulating bile acid levels but not glucose homeostasis in Gcgr Molecular metabolism, 2018, Volume: 16 Topics: Animals; Bile Acids and Salts; Blood Glucose; Body Weight; Diet, High-Fat; Gastrectomy; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptide-2 Receptor; Glucose; Glucose Tolerance Test; Homeostasis; Insulin; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Proglucagon; Receptors, G-Protein-Coupled; Receptors, Glucagon; Signal Transduction; Weight Loss	2018
Comments on "Pharmacological Characterization of Apraglutide a Novel Long-Acting Peptidic Glucagon-Like Peptide-2 Agonist for the Treatment of Short Bowel Syndrome". The Journal of pharmacology and experimental therapeutics, 2021, Volume: 377, Issue:3 Topics: Glucagon; Glucagon-Like Peptide 2; Humans; Peptides; Short Bowel Syndrome	2021
Mutational Landscape of the Proglucagon-Derived Peptides. Frontiers in endocrinology, 2021, Volume: 12 Topics: Amino Acid Sequence; Datasets as Topic; DNA Mutational Analysis; Gene Frequency; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Humans; Models, Molecular; Mutation, Missense; Pharmacogenomic Testing; Proglucagon; Protein Precursors; Protein Structure, Secondary	2021
Variation in the Evolution and Sequences of Proglucagon and the Receptors for Proglucagon-Derived Peptides in Mammals. Frontiers in endocrinology, 2021, Volume: 12 Topics: Amino Acid Sequence; Animals; Evolution, Molecular; Genetic Variation; Genome; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptide-2 Receptor; Mammals; Phylogeny; Proglucagon; Receptors, Glucagon	2021
[Gly²]-GLP-2, But Not Glucagon or [D-Ala²]-GLP-1, Controls Collagen Crosslinking in Murine Osteoblast Cultures. Frontiers in endocrinology, 2021, Volume: 12 Topics: Animals; Cells, Cultured; CHO Cells; Collagen; Cricetulus; Gastrointestinal Hormones; Gene Expression; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucagon-Like Peptide-2 Receptor; Mice; Osteoblasts; Protein Multimerization	2021
A conversation with Dan Drucker. The Journal of clinical investigation, 2021, 09-15, Volume: 131, Issue:18 Topics: Animals; Dipeptidyl-Peptidase IV Inhibitors; Endocrinology; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; History, 20th Century; History, 21st Century; Humans; Ontario; Patents as Topic	2021
Involvement of trigeminal axons in nose-to-brain delivery of glucagon-like peptide-2 derivative. Journal of controlled release : official journal of the Controlled Release Society, 2022, Volume: 351 Topics: Axons; Brain; Cell-Penetrating Peptides; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2	2022
Circulating levels of proglucagon-derived peptides are differentially regulated by the glucagon-like peptide-1 agonist liraglutide and the centrally acting naltrexone/bupropion and can predict future weight loss and metabolic improvements: A 6-month long Diabetes, obesity & metabolism, 2023, Volume: 25, Issue:9 Topics: Bupropion; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Humans; Liraglutide; Naltrexone; Obesity; Overweight; Peptides; Proglucagon; Weight Loss	2023