glucagon has been researched along with glucagon-like peptide 1 (7-36)amide in 336 studies
| Studies (glucagon) | Trials (glucagon) | Recent Studies (post-2010) (glucagon) | Studies (glucagon-like peptide 1 (7-36)amide) | Trials (glucagon-like peptide 1 (7-36)amide) | Recent Studies (post-2010) (glucagon-like peptide 1 (7-36)amide) |
|---|---|---|---|---|---|
| 26,039 | 1,498 | 3,054 | 404 | 54 | 38 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 27 (8.04) | 18.7374 |
| 1990's | 204 (60.71) | 18.2507 |
| 2000's | 100 (29.76) | 29.6817 |
| 2010's | 5 (1.49) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Marks, V | 1 |
| Ahrén, B; Efendic, S; Gutniak, M; Holst, JJ; Orskov, C | 1 |
| Bartels, E; Creutzfeldt, W; Ebert, R; Nauck, MA; Orskov, C | 2 |
| Kawai, K; Ohashi, S; Suzuki, S; Watanabe, Y; Yamashita, K | 1 |
| D'Alessio, DA; Ensinck, JW | 1 |
| Creutzfeldt, W; Schmidt, WE; Schulze, A; Siegel, EG | 1 |
| Fukuda, M; Hotta, M; Ikegami, H; Morimoto, S; Ogihara, T; Shima, K | 1 |
| Barthel, M; Ebert, R; Köhler, H; Nustede, R; Schafmayer, A; Schröter-Printzen, I | 1 |
| Fehmann, HC; Göke, B; Göke, R | 1 |
| Orskov, C; Poulsen, SS | 1 |
| Bloom, SR; Domin, J; Ghatei, MA; Kanse, S; Kreymann, B | 1 |
| Arnold, R; Fehmann, HC; Göke, B; Göke, R; Richter, G; Trautmann, ME; Weber, V | 1 |
| Arnold, R; Bächle, R; Fehmann, HC; Göke, B; Göke, R; Wagner, B | 1 |
| Eguchi, H; Fukase, N; Manaka, H; Sasaki, H; Sekikawa, A; Suda, K; Takahashi, H; Tominaga, M | 1 |
| Ahrén, B; Fridolf, T | 3 |
| Arnold, R; Göke, B; Göke, R; Richter, G; Schmidt, H | 1 |
| Ahrén, B; Böttcher, G; Fridolf, T; Sundler, F | 1 |
| Fletcher, J; Marks, V; Morgan, L; Oben, J | 1 |
| Ebert, R | 1 |
| Kawai, K; Mukai, H; Murayama, Y; Ohashi, S; Suzuki, S; Yamashita, K | 1 |
| Arnold, R; Göke, B; Göke, R; Richter, G | 2 |
| Cha, T; Hirota, M; Ikegami, H; Noma, Y; Ogihara, T; Ohboshi, C; Tahara, Y; Yamamoto, Y; Yamato, E; Yoneda, H | 1 |
| Aulehner, R; Classen, M; Schmid, R; Schusdziarra, V; Weigert, N | 1 |
| Kawai, K; Mukai, H; Murayma, Y; Ohashi, S; Suzuki, S; Yamashita, K | 1 |
| Shima, K | 1 |
| Bloom, SR; Ghatei, MA; Kreymann, B; Nikou, GC; O'Halloran, DJ | 1 |
| Arnold, R; Fehmann, HC; Göke, B; Göke, R; Haus, E; Richter, G; Trautmann, ME | 1 |
| Fehmann, HC; Göke, B; Göke, R; Richter, G; Trautmann, M | 1 |
| Habener, JF; Hendrick, GK; Mojsov, S; Weir, GC | 1 |
| Itoh, H; Komatsu, R; Kono, N; Matsuyama, T; Namba, M; Tarui, S; Watanabe, N | 1 |
| Arnold, R; Fehmann, HC; Göke, B; Göke, R; Trautmann, ME | 1 |
| Kawai, K; Mukai, H; Ohashi, S; Suzuki, S; Yamashita, K | 1 |
| Hirota, M; Ohboshi, C; Shima, K; Yoshimoto, S | 1 |
| Bloom, SR; Burnet, P; Diani, AR; Ghatei, MA; Kanse, S; Kreymann, B; Williams, G | 1 |
| Conlon, JM; Göke, R | 1 |
| Bloom, SR; Ghatei, MA; Kanse, SM; Kreymann, B | 1 |
| Ginier, P; Levin, SR; Soon-Shiong, P; Swafford, G | 1 |
| Itoh, H; Komatsu, R; Matsuyama, T; Namba, M; Tarui, S; Watanabe, N | 1 |
| Bloom, SR; Ghatei, MA; Kanse, S; Kreymann, B; Williams, G; Yiangou, Y | 1 |
| Honda, M; Ikeda, T; Ito, Y; Mashiba, H; Mokuda, O; Tominaga, M; Yoshida, T | 1 |
| Itoh, H; Komatsu, R; Kono, N; Matsuyama, T; Miyagawa, J; Namba, M; Tarui, S; Watanabe, N | 1 |
| Creutzfeldt, W; Ebert, R | 2 |
| Brown, JC | 1 |
| Björntorp, P | 1 |
| Lauritsen, KB | 1 |
| Creutzfeldt, W; Ebert, R; Unger, H | 1 |
| Akerblom, HK; Knip, M; Kouvalainen, K; Lautala, P; Martin, JM | 1 |
| Levy, N; Stermer, E | 1 |
| Creutzfeldt, W | 2 |
| Christensen, KC; Lauritsen, KB; Lauritzen, JB | 1 |
| Levin, SR | 1 |
| Bode, HP; Göke, B; Göke, R; Lankat-Buttgereit, B; van Eyll, B | 1 |
| Ebner, K; Fürnsinn, C; Waldhäusl, W | 1 |
| Dissing, S; Gromada, J; Rorsman, P; Wulff, BS | 1 |
| Creutzfeldt, W; Holst, JJ; Nauck, MA; Orskov, C; Qualmann, C | 1 |
| Deacon, CF; Holst, JJ; Nauck, MA; Pridal, L; Toft-Nielsen, M; Willms, B | 1 |
| Holst, JJ; Nauck, MA; Orskov, C; Ritzel, R | 1 |
| Göke, B; Göke, R; McGregor, GP | 1 |
| Bloom, SR; Ghatei, MA; Kruszynska, YT; McIntyre, N | 1 |
| Okuda, Y; Yamashita, K | 1 |
| Brown, JC; Jia, X; Ma, P; McIntosh, CH; Pederson, RA | 1 |
| Arnold, R; Fehmann, HC; Göke, B; Göke, R; Herrmann, C; Richter, G | 1 |
| Bridenbaugh, S; Fieseler, P; Holst, JJ; Martell, J; Nauck, MA; Nustede, R; Orskov, C | 1 |
| Bataille, D; Gros, L; Hollande, F; Kervran, A; Thorens, B | 1 |
| Arnold, R; Fehmann, HC; Göke, B; Göke, R | 1 |
| Alcántara, A; Clemente, F; Delgado, E; Galera, C; Luque, MA; Trapote, MA; Valverde, I; Villanueva-Peñacarrillo, ML | 1 |
| Bokvist, K; Dissing, S; Frøkjaer-Jensen, J; Gromada, J; Renström, E; Rorsman, P; Wulff, BS | 1 |
| Fehmann, HC; Göke, B; Göke, R; Kolligs, F | 1 |
| Weir, GC | 1 |
| Bloom, SR; Ghatei, MA; Owji, AA; Smith, DM; Wang, RM; Wang, Z | 1 |
| Deacon, S; Elliott, RM; Marks, V; Morgan, LM; Tredger, JA; Wright, J | 1 |
| Britsch, S; Drews, G; Gregor, M; Krippeit-Drews, P; Lang, F | 1 |
| Fletcher, JM; Knapper, JM; Morgan, LM; Puddicombe, SM | 1 |
| Alcántara, AI; Clemente, F; Delgado, E; Valverde, I; Villanueva-Peñacarrillo, ML | 1 |
| Brown, JC; Jia, X; Kwok, YN; McIntosh, CH; Pederson, RA | 1 |
| Arnold, R; Bothe-Sandfort, E; Eissele, R; Eng, J; Göke, B; Koop, H | 1 |
| Boyd, AE; Fehmann, HC; Göke, B; Jiang, J; Schweinfurth, J; Wheeler, MB | 1 |
| Göke, B; Göke, R; Just, R; Lankat-Buttgereit, B | 1 |
| Allescher, HD; Classen, M; Dehne, K; Holst, JJ; Polack, A; Schepp, W; Schmidtler, J; Schusdziarra, V | 1 |
| Bernard, C; Chayvialle, JA; Cuber, JC; Plaisancie, P | 1 |
| Brady, EJ; Cullinan, CA; Leibowitz, MD; Saperstein, R | 1 |
| Gallwitz, B; Mentlein, R; Schmidt, WE | 1 |
| Bataille, D; Gros, L; Kervran, A; Thorens, B | 1 |
| Fehmann, HC; Göke, B; Göke, R; Jiang, J; Lankat-Buttgereit, B; Stöckmann, F | 1 |
| Kawai, K; Ohashi, S; Suzuki, S; Watanabe, Y; Yamashita, K; Yokota, C | 1 |
| Barragán, JM; Blázquez, E; Rodríguez, RE | 1 |
| D'Alessio, DA; Ensinck, JW; Kahn, SE; Leusner, CR | 1 |
| Delgado, E; Mérida, E; Molina, LM; Valverde, I; Villanueva-Peñacarrillo, ML | 1 |
| Thorens, B; Waeber, G | 1 |
| Fletcher, JM; Knapper, JM; Marks, V; Morgan, LM; Puddicombe, SM | 1 |
| Delgado, E; Mérida, E; Trapote, MA; Valverde, I; Villanueva-Peñacarrillo, ML | 1 |
| Göke, B; Göke, R; Kolligs, F; Lankat-Buttgereit, B; Richter, G | 1 |
| Fujiyama, K; Hoshino, T; Ikeda, T; Mashiba, H; Ochi, H; Ohtani, I; Takeuchi, T; Tanaka, Y | 1 |
| Brunner, HR; Grouzmann, E; Nicod, P; Thompson, N; Waeber, B; Waeber, G | 1 |
| Eng, J; Fehmann, HC; Göke, B; Göke, R; Krause, M; Linn, T; Schmidt, H | 1 |
| Itoh, K; Nakata, M; Yada, T | 1 |
| Creutzfeldt, W; Holst, JJ; Kleine, N; Nauck, MA; Orskov, C; Willms, B | 1 |
| Creutzfeldt, W; Ebert, R; Heimesaat, MM; Holst, JJ; Nauck, MA; Orskov, C | 1 |
| Holst, JJ; Orskov, C; Wettergren, A | 2 |
| Beak, SA; Bloom, SR; Choi, SJ; Edwards, CM; Ghatei, MA; Gunn, I; Heath, MM; Herbert, J; Lambert, PD; Meeran, K; O'Shea, D; Smith, DM; Taylor, GM; Turton, MD; Wilding, JP | 1 |
| Frölich, M; Gooszen, HG; Guicherit, OR; Lemkes, HH; van der Burg, MP; van Suylichem, PT | 2 |
| Gedulin, BR; Rink, TJ; Young, AA | 1 |
| D'Alessio, DA; Eng, J; Ensinck, JW; Koerker, D; Laschansky, E; Prigeon, R; Vogel, R | 1 |
| Arnold, R; Göke, B; Katschinski, M; Schäfer, T; Schirra, J; Wank, U; Weidmann, C | 1 |
| Adelhorst, K; Holst, JJ; Ingwersen, SH; Kirk, O; Larsen, FS; Pridal, L | 1 |
| Göke, R; Larsen, PJ; Mikkelsen, JD; Sheikh, SP | 1 |
| Fletcher, JM; Heath, A; Knapper, JM; Marks, V; Morgan, LM | 1 |
| Aponte, GW; Heller, RS | 1 |
| Gyomorey, S; Li, X; Mathi, SK; Su, RC; Takhar, S; Wheeler, MB | 1 |
| Holst, JJ; Nauck, MA; Orskov, C; Siemsglüss, J | 1 |
| Blazquez, E; Calvo, JC; Gisolfi, CV; Mora, F | 1 |
| Hanafusa, T; Kuwajima, M; Matsumura, T; Matsuzawa, Y; Miki, H; Mineo, I; Miyagawa, J; Nakajima, H; Namba, M; Nishimura, T | 1 |
| Ben-Hamida, A; Man, WK; Spencer, J | 1 |
| Ahren, B | 1 |
| Creutzfeldt, WO; Holst, JJ; Kleine, N; Nauck, MA; Orskov, C; Willms, B | 1 |
| Beak, SA; Bloom, SR; Gunn, I; O'Shea, D; Turton, MD | 1 |
| Frölich, M; Gooszen, HG; Guicherit, OR; van der Burg, MP | 1 |
| Asa, SL; Brubaker, PL; Drucker, DJ; Erlich, P | 1 |
| Crespel, A; De Boisvilliers, F; Gros, L; Kervran, A | 1 |
| Ahrén, B; Holst, JJ; Lindskog, S; Steffens, AB; Van Dijk, G | 1 |
| Federlin, K; Göke, B; Linn, T; Schneider, K | 1 |
| Alcántara, AI; Clemente, F; Galera, C; López-Delgado, MI; Morales, M; Trapote, MA; Valverde, I; Villanueva-Peñacarrillo, ML | 1 |
| Gama, R; Hampton, S; Marks, V; Morgan, L; Norris, F; Watkins, S; Wright, J | 1 |
| Demuth, HU; McIntosh, CH; Pauly, RP; Pederson, RA; Rosche, F; Wermann, M | 1 |
| Ahrén, B; Karlsson, S; Simonsson, E | 1 |
| Fletcher, JM; Knapper, JM; Morgan, LM | 1 |
| Ahrén, B; Gutniak, MK; Heiber, SJ; Holst, JJ; Juneskans, OT; Larsson, H | 1 |
| Efendic, S; Guenifi, A; Gutniak, MK; Hellström, PM; Holst, JJ; Juntti-Berggren, L | 1 |
| Alvarez, E; Blázquez, E; Chowen, JA; Eng, J; Gomez, R; Navarro, M; Rodriquez de Fonseca, F; Zueco, JA | 1 |
| Barrow, BA; Buchanan, KD; Gribble, FM; Levy, JC; Rachman, J; Turner, RC | 1 |
| Nauck, M | 1 |
| Alberti, KG; Holst, JJ; Møller, J; Møller, N; Orskov, C; Orskov, L; Schmitz, O | 1 |
| Kawai, K; Nakagawa, Y; Ohashi, S; Suzuki, H; Yamashita, K | 1 |
| Fink-Jensen, A; Göke, R; Jessop, DS; Larsen, PJ; Møller, M; Sheikh, SP; Tang-Christensen, M | 1 |
| Bernstein, IL; Burn, P; Campfield, LA; Donahey, JC; Seeley, RJ; Smith, FJ; Thiele, TE; Van Dijk, G; Woods, SC | 1 |
| Beck-Nielsen, HB; Holst, JJ; Vaag, AA; Vølund, A | 1 |
| Kieffer, TJ; Kofod, H; Kwong, J; McIntosh, CH; Pauly, R; Pederson, RA | 1 |
| Faulkner, A; Martin, PA | 3 |
| Nakabayashi, H; Nakagawa, A; Niijima, A; Nishizawa, M; Takeda, R | 1 |
| Nakabayashi, H; Nakagawa, A; Niijima, A; Nishizawa, M; Uchida, K | 1 |
| Barragán, JM; Blázquez, E; Eng, J; Rodríguez, RE | 1 |
| Beales, IL; Calam, J | 1 |
| Creutzfeldt, W; Holst, JJ; Nauck, MA; Orskov, C; Werner, J; Willms, B; Wollschläger, D | 1 |
| Beety, JM; Howland, R; Marks, V; Morgan, LM; Ranganath, LR; Wright, JW | 1 |
| Arnalich, F; Barbado, J; Codoceo, R; Garcés, MC; Gómez-Cerezo, J; Soto, A; Vázquez, JJ | 1 |
| Bernstein, IL; Seeley, RJ; Thiele, TE; van Dijk, G; Woods, SC | 1 |
| Deeg, MA; Verchere, CB | 1 |
| Knudsen, LB; Pridal, L | 1 |
| Behme, MT; Dupré, J; Hramiak, IM; McDonald, TJ | 1 |
| Berghöfer, P; Fehmann, HC; Göke, B; Peterson, RG; Schneider, K | 1 |
| Ding, WG; Gromada, J | 1 |
| Caprio, S; Limb, C; Pederson, R; Sherwin, RS; Tamborlane, WV | 1 |
| Alcántara, AI; Clemente, F; Delgado, E; López-Delgado, MI; Luque, MA; Malaisse, WJ; Morales, M; Valverde, I; Villanueva-Peñacarrillo, ML | 1 |
| Boesby, S; Holst, JJ; Maina, P; Wettergren, A | 1 |
| Göke, B; Lankat-Buttgereit, B | 1 |
| Göke, B; Göke, R; Hupe-Sodmann, K; McGregor, GP; Thole, HH; Voigt, K; Zimmermann, B | 1 |
| Barg, S; Ding, WG; Gromada, J; Renström, E; Rorsman, P | 1 |
| Bloom, SR; Edwards, AV; Edwards, CM | 1 |
| Beday, A; Eng, J; Montrose-Rafizadeh, C; Pritchette, LA; Rodgers, BD; Yang, H | 1 |
| Dobashi, Y; Kanno, T; Suga, S; Wakui, M | 1 |
| Fontela, T; Ghiglione, M; Hermida, OG; Uttenthal, LO; van Delft, J | 1 |
| Adams, LG; Montrose, MH; Montrose-Rafizadeh, C; Roth, J; Wang, Y; Yang, H | 1 |
| McMahon, LR; Wellman, PJ | 2 |
| Clemente, F; Perea, A; Valverde, I; Villanueva-Peñacarrillo, ML; Viñambres, C | 1 |
| Ettler, R; Holst, JJ; Nauck, MA; Niedereichholz, U; Orskov, C; Ritzel, R; Schmiegel, WH | 1 |
| Bloom, SR; Gunn, I; O'Shea, D | 1 |
| Bailbé, D; Dachicourt, N; Doaré, L; Kergoat, M; Portha, B; Serradas, P | 1 |
| Bokvist, K; Ding, WG; Gromada, J; Holst, JJ; Nielsen, JH; Rorsman, P | 1 |
| Flamez, D; Ling, Z; Moens, K; Pipeleers, D; Schuit, F; Van Schravendijk, C | 1 |
| Chisholm, C; Fung, LC; Greenberg, GR | 1 |
| Gromada, J; Holst, JJ; Rorsman, P | 1 |
| Arnold, R; Beglinger, C; Göke, B; Hildebrand, P; Katschinski, M; Leicht, P; Schirra, J | 1 |
| Deacon, CF; Holst, JJ; Jacobsen, O; Knudsen, LB; Madsen, K; Wiberg, FC | 1 |
| Nakata, M; Tanaka, H; Yada, T; Yaekura, K | 1 |
| Compton, DS; Davis, HR; France, CF; Graziano, MP; Hoos, LM; Mullins, DE; Pines, JM; Strader, CD; Sybertz, EJ; Van Heek, M | 1 |
| Matsuno, S; Naito, H; Sasaki, I | 1 |
| Benito, E; Blazquez, E; Bosch, MA | 1 |
| Larsen, PJ; Tang-Christensen, M; Vrang, N | 1 |
| Keller, U; Ninnis, R; Shalev, A | 1 |
| Luque, MA; Márquez, L; Trapote, MA; Valverde, I; Villanueva-Peñacarrillo, ML | 1 |
| Bloom, SR; Brynes, AE; Edwards, CM; Frost, GS; Ghatei, MA | 2 |
| Bergmann, J; Holst, JJ; Nauck, MA; Ritzel, R; Schmiegel, W; Seifarth, C | 1 |
| Holst, JJ; Wettergren, A; Wøjdemann, M | 2 |
| Bernstein, IL; D'Alessio, D; Eng, J; Seeley, RJ; Thiele, TE; van Dijk, G; Woods, SC | 1 |
| Hansen, BF; Jensen, P; Nepper-Christensen, E; Skjølstrup, B | 1 |
| Gutniak, M | 1 |
| Flier, ES; Gillette, J; Ludwig, DS; Maratos-Flier, E; Tritos, NA; Vicent, D | 1 |
| Abdel-Wahab, YH; Conlon, JM; Flatt, PR; O'Harte, FP | 1 |
| Eckart, K; Leonhardt, U; Ottleben, M; Ramadori, G; Ritzel, U; Rühmann, A; Spiess, J | 1 |
| Holst, JJ; Pridal, L; Wettergren, A; Wøjdemann, M | 1 |
| Bach, I; Holst, JJ; Nauck, MA; Orskov, C; Richter, S; Schmiegel, W; Weber, I | 1 |
| Bloom, SR; Edwards, CM; Ghatei, MA; Todd, JF | 1 |
| Marks, V; Morgan, L; Ranganath, L; Sedgwick, I; Wright, J | 1 |
| Abusnana, S; Bloom, SR; Choi, SJ; Edwards, CM; Ghatei, MA; Goldstone, AP; Gunn, I; Heath, MM; Meeran, K; O'Shea, D; Rossi, M; Small, CJ; Steere, J; Sunter, D; Taylor, GM; Turton, MD | 1 |
| Alvarez, E; Blázquez, E; Chowen, JA; Navarro, M; Rodríguez-Fonseca, F; Roncero, I; Zueco, JA | 1 |
| Marks, V; Morgan, L; Norris, F; Ranganath, L; Wright, J | 1 |
| Nauck, MA | 1 |
| Fernandez, J; Valdeolmillos, M | 1 |
| Hampton, SM; Livesey, G; Mathers, JC; Morgan, LM; Robertson, MD | 1 |
| Brynes, A; Frost, G; Leeds, A | 1 |
| Fenselau, S; Hermansen, K; Holst, JJ; Lousen, T; Rasmussen, O; Schrezenmeir, J; Thomsen, C | 1 |
| Tseng, CC; Wolfe, MM; Zhang, XY | 1 |
| Holst, JJ; Hopfenmüller, W; Messerschmidt, D; Plöckinger, U; Quabbe, HJ | 1 |
| Efendic, S; Eskilsson, A; Hassan, M; Jacobsson, H; Jonsson, C; Larsson, S; Nilsson, C; Refai, E | 1 |
| Holst, JJ; Madsbad, S; Toft-Nielsen, MB | 1 |
| Delzenne, NM; Kok, NN | 1 |
| Gallwitz, B; Schmidt, WE | 1 |
| Goto, N; Kameyama, T; Oka, JI | 1 |
| Deacon, CF; Hansen, L; Holst, JJ; Orskov, C | 1 |
| Alberti, KG; Gravholt, CH; Holst, JJ; Nyholm, B; Schmitz, O; Shearing, PA; Sturis, J; Walker, M | 1 |
| Balkan, B; Holst, JJ; Kwasnik, L; Li, X; Miserendino, R | 1 |
| Rinaman, L | 1 |
| Barragán, JM; Blázquez, E; Eng, J; Rodríguez, R | 1 |
| Habener, JF; Kieffer, TJ | 1 |
| Ban, N; Fujimoto, S; Hashimoto, H; Ihara, Y; Jomori, T; Kajikawa, M; Kubota, A; Kuroe, A; Miyawaki, K; Miyazaki, J; Niwa, H; Seino, Y; Tashiro, F; Tsuda, K; Yamada, Y; Yamashita, T; Yano, H | 1 |
| Bungo, T; Furuse, M; Hasegawa, S; Masuda, Y; Saito, N; Shimojo, M; Sugahara, K | 1 |
| Hedetoft, C; Holst, JJ; Larsen, S; Sheikh, SP | 1 |
| Fölsch, UR; Gallwitz, B; Schmidt, WE; Siegel, EG | 1 |
| Alvarez, E; Blázquez, E; Chowen, JA; de Fonseca, FR; García-Segura, LM; Navarro, M | 1 |
| Thiele, TE; van Dijk, G | 1 |
| Benoit, S; Blake, K; D'Alessio, D; Eng, J; Rushing, PA; Seeley, RJ; Woods, SC | 1 |
| Flatt, PR; Lawlor, A; Mooney, MH; O'Harte, FP | 1 |
| Ito, T; Kawai, K; Kawakami, S; Nakabayashi, H; Nakagawa, A; Niijima, A; Nishizawa, M; Uchida, K | 1 |
| Fritsche, A; Hardt, E; Häring, H; Schützenauer, S; Stefan, N; Stumvoll, M | 1 |
| Basu, A; Basu, R; Holst, JJ; Rizza, RA; Shah, P; Vella, A | 1 |
| Alvarez, E; Blázquez, E; Chowen, JA; Eng, J; Gómez, R; Maestre, O; Muñoz, RM; Navarro, M; Rodriquez de Fonseca, F; Roncero, I | 1 |
| Ebinger, M; Fehmann, HC; Fussgaenger, RD; Jehle, DR; Jehle, PM | 1 |
| Fritsche, A; Hardt, E; Häring, H; Stefan, N; Stumvoll, M | 1 |
| Bojanowska, E; Stempniak, B | 3 |
| Balkan, B; Li, X | 1 |
| Barilli, AL; Dei Cas, A; Dell'Anna, C; Gnudi, A; Iotti, M; Lugari, R; Marani, B; Orlandini, A; Ugolotti, D; Zandomeneghi, R | 1 |
| Balkan, B | 1 |
| Christiansen, JS; Fineman, MS; Fisker, S; Holst, JJ; Jørgensen, JO; Madsbad, S; Nyholm, B; Rosenfalck, AM; Schmitz, O | 1 |
| Flatt, PR; Kelly, CM; McKillop, AM; Mooney, MH; O'Harte, FP | 1 |
| Niki, I; Nimura, Y; Niwa, T | 1 |
| Arima, T; Hashiguchi, S; Yada, T | 1 |
| Abdel-Halim, SM; Ahrén, B; Guenifi, A | 1 |
| Boyd, AE; Civelek, VN; Corkey, BE; Deeney, JT; Dillon, JS; Hamilton, JA; Korchak, HM; Richard, AM; Tornheim, K; Yaney, GC | 1 |
| Delzenne, NM; Kok, N | 1 |
| Kuwahara, A; Suzuki, M | 1 |
| Bailbe, D; Marie, JC | 1 |
| Basu, A; Basu, R; Camilleri, M; Holst, JJ; Rizza, RA; Schwenk, FW; Shah, P; Vella, A | 1 |
| Arias-Díaz, J; Balibrea, JL; Blázquez, E; Garcia, C; Vara, E | 1 |
| Bardini, G; Ciani, S; Cremasco, F; Mannucci, E; Mencucci, A; Messeri, G; Ognibene, A; Pierazzuoli, E; Rotella, CM | 1 |
| Holst, JJ; Madsbad, S; Taskiran, M; Toft-Nielsen, MB; Zander, M | 1 |
| Burcelin, R; Da Costa, A; Drucker, D; Thorens, B | 1 |
| Brown, TA; Busselen, S; Perfetti, R; Velikina, R | 1 |
| Astrup, A; Buemann, B; Juul Holst, J; Lysgård Madsen, J; Toubro, S; Verdich, C | 1 |
| Kimura, I; Kobayashi, M; Ohgaku, S; Sasamoto, H; Sasamura, T; Sugihara, Y | 1 |
| Ahrén, B; Holst, JJ; Johnson, O; Olsson, T; Rask, E; Seckl, J; Söderberg, S | 1 |
| Astrup, A; Beglinger, C; Flint, A; Gutzwiller, JP; Hellström, PM; Holst, JJ; Long, SJ; Morgan, LM; Näslund, E; Verdich, C | 1 |
| Barilli, AL; Dei Cas, A; Gnudi, A; Iotti, M; Lugari, R; Marani, B; Orlandini, A; Ugolotti, D; Zandomeneghi, R | 1 |
| Kashima, Y; Miki, T; Miyazaki, M; Ozaki, N; Seino, S; Shibasaki, T; Yano, H | 1 |
| Holst, JJ; Orskov, C | 1 |
| Feddersen, CO; Golpon, HA; Puechner, A; Welte, T; Wichert, PV | 1 |
| Mistry, M; Moreno, C; Roman, RJ | 1 |
| Holst, JJ; Juntunen, KS; Liukkonen, KH; Mykkänen, HM; Niskanen, LK; Poutanen, KS | 1 |
| Arnold, R; Göke, B; Katschinski, M; Schirra, J; Wank, U | 1 |
| Heilig, M; Möller, C; Rimondini, R; Sommer, W; Thorsell, A | 1 |
| Andres, R; Egan, JM; Elahi, D; Meneilly, GS; Muller, DC; Veldhuist, J | 1 |
| Deacon, CF; Holst, JJ; Møller, S; Plamboeck, A | 1 |
| Ahren, B; Cederquist, K; Forsberg, H; Holst, JJ; Johansson, A; Olsson, T; Seckl, JR | 1 |
| D'Alessio, DA; Greenbaum, CJ; Prigeon, RL | 1 |
| Alvarez, CE; Sutcliffe, JG | 1 |
| Habener, JF; Kemp, DM; Ubeda, M | 1 |
| Rinaman, L; Rothe, EE | 1 |
| Holst, JJ | 1 |
| Chisholm, C; Greenberg, GR | 1 |
| Baker, B; Chapman, I; Horowitz, M; Morris, H; Vozzo, R; Wishart, JM; Wittert, GA | 1 |
| Seino, Y; Yamada, Y | 1 |
| Matsuyama, T | 1 |
| Taminato, T | 1 |
| Bergman, RN; Brubaker, PL; Dea, MK; Kabir, M; Kim, SP; Mittelman, SD; van Citters, GW | 1 |
| Kashima, Y; Seino, S; Shibasaki, T | 1 |
| D'Alessio, DA; Kinzig, KP; Seeley, RJ | 1 |
| Aguilar-Bryan, L; Bryan, J; Crane, A; Hu, M; Nakazaki, M; Seghers, V; Ullrich, S | 1 |
| Blat, S; Chauvin, A; Cuber, JC; Guérin, S; Malbert, CH; Morgan, L; Sève, B | 1 |
| Chang, AM; Halter, JB | 1 |
| Astrup, A; Feldt-Rasmussen, U; Holst, JJ; Mersebach, H; Svendsen, OL | 1 |
| Demuth, HU; Doty, T; Ehses, JA; Lynn, FC; Martin, J; McIntosh, CH; Pamir, N; Pederson, RA; Piteau, S; Pospisilik, JA | 1 |
| Egan, JM; Ehlers, MR; Elahi, D; Habener, JF; McIntosh, CH; Meneilly, GS; Pederson, RA | 1 |
| Flatt, PR; Gault, VA; Green, BD; Harriott, P; Mooney, MH; O'Harte, FP | 1 |
| Gallwitz, B; Meier, JJ; Nauck, MA | 1 |
| Briaud, I; Dickson, LM; Lingohr, MK; Rhodes, CJ; Wrede, CE | 1 |
| Carr, RD; Deacon, CF; Holst, JJ; Plamboeck, A | 1 |
| D'Alessio, DA; Fuller, BD; Paty, BW; Prigeon, RL; Vahl, TP | 1 |
| Yamada, Y | 1 |
| Holst, JJ; Juul, AG; Krarup, T; Madsbad, S; Sonne, J; Vilsbøll, T; Vølund, A | 1 |
| Ehlers, MR; Gutniak, M; Kavianipour, M; Malmberg, K; Ronquist, G; Ryden, L; Wikström, G | 1 |
| Bollag, RJ; Ding, KH; Isales, CM; Mulloy, AL; Zhong, Q | 1 |
| D'Alessio, DA; Figueiredo, HF; Figueredo, HF; Herman, JP; Kinzig, KP; Murphy, EK; Sakai, RR; Seeley, RJ; Vahl, TP | 1 |
| Bryant, L; Feinle, C; Horowitz, M; Jones, KL; Lei, Y; Meyer, JH; O'Donovan, D; Pilichiewicz, A; Wishart, JM | 1 |
| Hansen, T; Holst, JJ; Johansen, A; Knop, FK; Krarup, T; Larsen, S; Madsbad, S; Pedersen, O; Vilsbøll, T | 1 |
| Brazg, R; D'Alessio, DA; Ehlers, MR; Harley, RE; Kay, HD; Klaff, LJ; Mathisen, AL; Schneider, R | 1 |
| Bailey, CJ; Flatt, PR; Gault, VA; Green, BD; Greer, B; Harriott, P; Irwin, N; Mooney, MH; O'Harte, FP | 2 |
| Dalgaard, M; Hermansen, K; Holst, JJ; Rasmussen, BM; Thomsen, C | 1 |
| El-Ouaghlidi, A; Gallwitz, B; Gallwitz, JB; Holst, JJ; Nauck, MA; Schmidt, WE; Schmiegel, W; Senkal, M; Vethacke, A; Walberg, J | 1 |
| Elahi, D; Mankad, S; Miske, G; Nikolaidis, LA; Shah, A; Shannon, RP; Sokos, GG | 1 |
| Ezaki, T; Nagai, K; Ohgawara, H; Tsuchiya, K; Tsuchiya, M | 1 |
| Allescher, HD; Erdmann, J; Kircher, F; Lippl, F; Schusdziarra, V | 1 |
| Buteau, J; El-Assaad, W; Joly, E; Prentki, M; Rhodes, CJ; Rosenberg, L | 1 |
| Delmeire, D; Flamez, D; Hinke, SA; Moens, K; Pipeleers, D; Schuit, F; Van Schravendijk, C | 1 |
| Bousquet-Gagnon, N; Bridon, DP; Carette, J; Castaigne, JP; Léger, R; Quraishi, O; Robitaille, M; Thibaudeau, K; van Wyk, P | 1 |
| Cani, PD; Delzenne, NM; Dewever, C | 1 |
| D'Alessio, DA; Liu, M; Qin, X; Sabo, M; Shen, H; Tso, P; Yang, Q; Zheng, S | 1 |
| Cani, PD; Catillon, G; Daubioul, CA; Delzenne, NM; Remacle, C; Reusens, B | 1 |
| Elahi, D; Nikolaidis, LA; Shannon, RP; Shen, YT | 1 |
| Byrne, MM; Jeibmann, A; Nieschlag, E; Simoni, M; Zahedi, S | 1 |
| Caperna, TJ; Garrett, WM; Poch, SM; Richards, MP; Shannon, AE | 1 |
| Carlson, O; Doyle, ME; Egan, JM; Juhaszova, M; Michopoulos, S; Petraki, K; Theodorakis, MJ | 1 |
| Demuth, HU; Kim, SJ; McIntosh, CH; Pederson, RA; Pospisilik, JA | 1 |
| Bhashyam, S; Bolukoglu, H; Parikh, P; Poornima, I; Shannon, RP; Shen, YT; Zhao, T | 1 |
| Accili, D; Buteau, J; Spatz, ML | 1 |
| Conlon, JM; Flatt, PR; Patterson, S | 1 |
| Beglinger, C; Castelli, MC; Drewe, J; Friedman, K; Huber, AR; Poller, B; Steinert, RE | 1 |
| Baughman, R; Boss, A; Cassidy, J; Costello, D; Damico, C; Marino, MT; Richardson, PC; van Marle, S; van Vliet, A | 1 |
| Bräuner-Osborne, H; Knudsen, LB; Lau, J; Møller Knudsen, S; Peters, GH; Reedtz-Runge, S; Rye Underwood, C; Schjellerup Wulff, B | 1 |
| Fukumori, R; Mita, T; Obitsu, T; Sugino, T; Taniguchi, K | 1 |
| Chen, X; Hermansen, K; Jeppesen, PB | 1 |
| Carlson, OD; Egan, JM; Elahi, D; Habener, JF; Meneilly, GS; Ruff, DA | 1 |
37 review(s) available for glucagon and glucagon-like peptide 1 (7-36)amide
| Article | Year |
|---|---|
Glucagon-like peptide-1(7-36) amide is a new incretin/enterogastrone candidate.
Topics: Animals; Brain; Digestive System; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Humans; Peptide Fragments; Peptides; Proglucagon; Protein Precursors; Protein Processing, Post-Translational; Receptors, Cell Surface; Receptors, Glucagon | 1991 |
New developments in the incretin concept.
Topics: Animals; Feedback; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Humans; Insulin; Insulin Secretion; Liver; Peptide Fragments | 1985 |
Gastric inhibitory polypeptide.
Topics: Adipose Tissue; Amino Acid Sequence; Animals; Diabetes Mellitus; Gastric Acid; Gastric Inhibitory Polypeptide; Gastrins; Gastrointestinal Diseases; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Humans; Insulin; Pancreatitis; Pepsin A; Peptide Fragments; Peptides; Proinsulin; Radioimmunoassay; Salivation; Splanchnic Circulation | 1982 |
GIP, incretin and gastrointestinal disease.
Topics: Animals; Blood Glucose; Celiac Disease; Digestive System; Duodenal Ulcer; Gastric Inhibitory Polypeptide; Gastrointestinal Diseases; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Tolerance Test; Humans; Ileum; Insulin; Intestine, Small; Islets of Langerhans; Jejunum; Peptide Fragments; Peptides; Vagotomy | 1983 |
Gastrointestinal peptides--rôle in pathophysiology and disease.
Topics: Autonomic Nervous System; Duodenal Ulcer; Endocrine Glands; Gastric Inhibitory Polypeptide; Gastrins; Gastrointestinal Diseases; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Insulin Secretion; Intestinal Absorption; Peptide Fragments; Peptides | 1982 |
[Diet therapy: role of incretin and dietary fibers].
Topics: Diabetes Mellitus; Diet Therapy; Dietary Fiber; Dietetics; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Peptide Fragments | 1995 |
[Incretin research in the development of new strategies of diabetes therapy].
Topics: Amino Acid Sequence; Blood Glucose; Diabetes Mellitus; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Molecular Sequence Data; Peptide Fragments; Peptides; Protein Precursors; Receptors, Glucagon | 1995 |
Glucagon-like peptide-I and the control of insulin secretion in the normal state and in NIDDM.
Topics: Animals; Cloning, Molecular; Diabetes Mellitus, Type 2; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Peptide Fragments; Peptides; Protein Precursors; Signal Transduction | 1993 |
Central glucagon-like peptide-I in the control of feeding.
Topics: Animals; Brain; Feeding Behavior; Genes, fos; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Humans; Hyperglycemia; Hyperinsulinism; Neurons; Peptide Fragments; Protein Precursors; Rats; Rats, Zucker; Receptors, Glucagon; Venoms | 1996 |
Nutrient-induced secretion and metabolic effects of glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1.
Topics: Adaptation, Physiological; Adipose Tissue; Animals; Coronary Disease; Diabetes Mellitus, Type 2; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Obesity; Peptide Fragments | 1996 |
Therapeutic potential of glucagon-like peptide 1 in type 2 diabetes.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 2; Gastric Emptying; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Hypoglycemic Agents; Infusions, Intravenous; Injections, Subcutaneous; Peptide Fragments; Postprandial Period; Protein Precursors | 1996 |
Control of appetite--the role of glucagon-like peptide-1 (7-36) amide.
Topics: Adipocytes; Animals; Appetite Regulation; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Neurotransmitter Agents; Obesity; Peptide Fragments | 1997 |
Cellular regulation of islet hormone secretion by the incretin hormone glucagon-like peptide 1.
Topics: Animals; Calcium; Diabetes Mellitus, Type 2; Exocytosis; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Humans; Ion Channels; Islets of Langerhans; Pancreatic Hormones; Peptide Fragments; Protein Precursors; Receptors, Glucagon | 1998 |
Surgical aspect of enteroinsular axis after gastrointestinal surgery with reference to incretin secretion.
Topics: Digestive System Surgical Procedures; Dumping Syndrome; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Neurotransmitter Agents; Pancreas; Peptide Fragments; Postoperative Complications | 1998 |
[GLP-1 (7-36) amide [GLIP-glucagon like insulinotropic peptide] as a potential treatment for NIDDM].
Topics: Animals; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Peptide Fragments | 1998 |
Glucagon-like peptide-1 (7-36) amide as a novel neuropeptide.
Topics: Animals; Brain; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Neuropeptides; Neurotransmitter Agents; Peptide Fragments; Rats; Receptors, Glucagon | 1998 |
Is glucagon-like peptide 1 an incretin hormone?
Topics: Animals; Diabetes Mellitus, Type 2; Digestion; Gastric Emptying; Gastrointestinal Hormones; Gastrointestinal Motility; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Insulin Secretion; Peptide Fragments; Protein Precursors | 1999 |
The glucagon-like peptides.
Topics: Amino Acid Sequence; Animals; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Molecular Sequence Data; Peptide Fragments; Peptides; Protein Precursors | 1999 |
[Hepatogenic diabetes--the current concepts of its pathophysiology and therapy].
Topics: Diabetes Mellitus; Diabetes Mellitus, Type 2; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Humans; Hypoglycemic Agents; Insulin Resistance; Liver; Liver Diseases; Peptide Fragments; Receptor, Insulin | 1999 |
Glucagon-like peptide-1 (7-36) amide: a central regulator of satiety and interoceptive stress.
Topics: Animals; Eating; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Neurotransmitter Agents; Peptide Fragments; Satiety Response; Stress, Psychological | 1999 |
Effects of fructans-type prebiotics on lipid metabolism.
Topics: Animals; Blood Glucose; Fatty Acids; Fructans; Gene Expression Regulation, Enzymologic; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Hypolipidemic Agents; Insulin; Lipid Metabolism; Lipoproteins; Liver; Neurotransmitter Agents; Oligosaccharides; Peptide Fragments; Rats; Triglycerides | 2001 |
The entero-insular axis in type 2 diabetes--incretins as therapeutic agents.
Topics: Animals; Diabetes Mellitus, Type 2; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Intestines; Islets of Langerhans; Peptide Fragments; Protein Precursors | 2001 |
Control of glucose homeostasis by incretin hormones.
Topics: Animals; Blood Glucose; Energy Metabolism; Gastrointestinal Hormones; Gastrointestinal Motility; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Gluconeogenesis; Glucose; Homeostasis; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Liver; Peptide Fragments | 1999 |
A meta-analysis of the effect of glucagon-like peptide-1 (7-36) amide on ad libitum energy intake in humans.
Topics: Adult; Appetite; Cross-Over Studies; Dose-Response Relationship, Drug; Eating; Energy Metabolism; Gastric Emptying; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Hunger; Infusions, Intravenous; Injections, Intravenous; Male; Obesity; Peptide Fragments; Randomized Controlled Trials as Topic; Satiety Response | 2001 |
Incretin hormones--an update.
Topics: Animals; Diabetes Mellitus, Type 2; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Humans; Insulin; Insulin Secretion; Intestinal Mucosa; Peptide Fragments; Protein Precursors | 2001 |
Glucose tolerance, glucose utilization and insulin secretion in ageing.
Topics: Aging; Diabetes Mellitus, Type 2; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glucose Tolerance Test; Humans; Insulin; Islets of Langerhans; Liver; Peptide Fragments | 2002 |
Gastric inhibitory polypeptide analogues: do they have a therapeutic role in diabetes mellitus similar to that of glucagon-like Peptide-1?
Topics: Animals; Diabetes Mellitus, Type 2; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Insulin Secretion; Peptide Fragments; Protein Precursors | 2002 |
[Review: regulation of glucose metabolism].
Topics: Animals; Blood Glucose; Diabetes Mellitus; Fasting; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucokinase; Glucose; Glucose Transporter Type 2; Glycogen; Humans; Insulin; Insulin Secretion; Intestinal Absorption; Liver; Monosaccharide Transport Proteins; Peptide Fragments; Protein Precursors | 2002 |
[Glucagon and GLP (glucagon-like peptide)].
Topics: Animals; Diabetes Mellitus; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Hyperglycemia; Peptide Fragments; Peptides; Protein Precursors | 2002 |
[Glucagon-like peptide-1 (GLP-1) receptor].
Topics: Animals; Diabetes Mellitus, Type 2; Exenatide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Humans; Insulin; Insulin Secretion; Peptide Fragments; Peptides; Polymorphism, Genetic; Protein Precursors; Receptors, Glucagon; Venoms | 2002 |
[Regulation of insulin secretion by incretins].
Topics: Animals; Carrier Proteins; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Guanine Nucleotide Exchange Factors; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Nuclear Proteins; Peptide Fragments | 2002 |
Aging and insulin secretion.
Topics: Adult; Aged; Aged, 80 and over; Aging; Diabetes Mellitus, Type 2; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Intolerance; Humans; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Middle Aged; Nutrition Surveys; Peptide Fragments | 2003 |
Glucagon-like peptide 1 and gastric inhibitory polypeptide: potential applications in type 2 diabetes mellitus.
Topics: Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Exenatide; Gastric Inhibitory Polypeptide; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Hypoglycemic Agents; Peptide Fragments; Peptides; Protease Inhibitors; Protein Precursors; Venoms | 2003 |
Neutral endopeptidase 24.11 and dipeptidyl peptidase IV are both involved in regulating the metabolic stability of glucagon-like peptide-1 in vivo.
Topics: Amino Acid Sequence; Animals; Dipeptidyl Peptidase 4; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Insulin Secretion; Kinetics; Mice; Molecular Sequence Data; Neprilysin; Peptide Fragments; Protease Inhibitors; Protein Precursors | 2003 |
[Current topics in endocrinology: incretin].
Topics: Animals; Cytokines; Diabetes Mellitus; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Peptide Fragments | 2003 |
Applications of dipeptidyl peptidase IV inhibitors in diabetes mellitus.
Topics: Amino Acid Sequence; Animals; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glucose Tolerance Test; Humans; Molecular Sequence Data; Peptide Fragments; Protease Inhibitors | 2006 |
Major contributions of comparative endocrinology to the development and exploitation of the incretin concept.
Topics: Amino Acid Sequence; Animals; Anura; Exenatide; Fishes; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Humans; Hypoglycemic Agents; Intestinal Mucosa; Molecular Sequence Data; Peptide Fragments; Peptides; Sequence Alignment; Venoms | 2006 |
44 trial(s) available for glucagon and glucagon-like peptide 1 (7-36)amide
| Article | Year |
|---|---|
Lack of effect of synthetic human gastric inhibitory polypeptide and glucagon-like peptide 1 [7-36 amide] infused at near-physiological concentrations on pentagastrin-stimulated gastric acid secretion in normal human subjects.
Topics: Adult; Blood Glucose; Gastric Acid; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Hormones; Humans; Infusions, Intravenous; Male; Pentagastrin; Peptide Fragments; Stimulation, Chemical | 1992 |
Pharmacokinetic, insulinotropic, and glucagonostatic properties of GLP-1 [7-36 amide] after subcutaneous injection in healthy volunteers. Dose-response-relationships.
Topics: Adult; Analysis of Variance; Blood Glucose; Body Mass Index; C-Peptide; Dose-Response Relationship, Drug; Fasting; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Injections, Subcutaneous; Insulin; Kinetics; Male; Peptide Fragments; Random Allocation; Reference Values; Time Factors | 1995 |
Physiological augmentation of amino acid-induced insulin secretion by GIP and GLP-I but not by CCK-8.
Topics: Adult; Amino Acids; Dietary Proteins; Eating; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Insulin Secretion; Male; Pancreas; Peptide Fragments; Peptides; Sincalide | 1995 |
Normalization of fasting hyperglycaemia by exogenous glucagon-like peptide 1 (7-36 amide) in type 2 (non-insulin-dependent) diabetic patients.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 2; Fasting; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glycated Hemoglobin; Humans; Hyperglycemia; Hypoglycemic Agents; Infusions, Intravenous; Kinetics; Male; Middle Aged; Peptide Fragments; Time Factors | 1993 |
Preserved incretin activity of glucagon-like peptide 1 [7-36 amide] but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus.
Topics: Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Clamp Technique; Glycated Hemoglobin; Humans; Insulin; Insulin Secretion; Kinetics; Male; Middle Aged; Peptide Fragments; Protein Precursors; Reference Values; Time Factors | 1993 |
Additive insulinotropic effects of exogenous synthetic human gastric inhibitory polypeptide and glucagon-like peptide-1-(7-36) amide infused at near-physiological insulinotropic hormone and glucose concentrations.
Topics: Administration, Oral; Adult; Blood Glucose; Drug Combinations; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Humans; Infusions, Intravenous; Insulin; Male; Osmolar Concentration; Pancreas; Peptide Fragments | 1993 |
Glucagonostatic actions and reduction of fasting hyperglycemia by exogenous glucagon-like peptide I(7-36) amide in type I diabetic patients.
Topics: Adult; Analysis of Variance; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Fasting; Fatty Acids, Nonesterified; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Male; Peptide Fragments; Protein Precursors; Time Factors | 1996 |
Potential therapeutic levels of glucagon-like peptide I achieved in humans by a buccal tablet.
Topics: Absorption; Adult; Blood Glucose; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Half-Life; Humans; Insulin; Middle Aged; Peptide Fragments; Radioimmunoassay; Tablets | 1996 |
Glucagon-like peptide I enhances the insulinotropic effect of glibenclamide in NIDDM patients and in the perfused rat pancreas.
Topics: Analysis of Variance; Animals; Diabetes Mellitus, Type 2; Drug Synergism; Drug Therapy, Combination; Gastric Emptying; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glyburide; Humans; In Vitro Techniques; Infusions, Intravenous; Insulin; Insulin Secretion; Islets of Langerhans; Middle Aged; Peptide Fragments; Perfusion; Protein Precursors; Rats; Rats, Sprague-Dawley; Treatment Failure | 1996 |
GLP-1 does not not acutely affect insulin sensitivity in healthy man.
Topics: 3-Hydroxybutyric Acid; Adult; Alanine; Analysis of Variance; Blood Glucose; C-Peptide; Calorimetry, Indirect; Fatty Acids, Nonesterified; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Clamp Technique; Humans; Hydroxybutyrates; Infusions, Intravenous; Insulin; Insulin Secretion; Lactates; Male; Neurotransmitter Agents; Peptide Fragments; Reference Values; Somatostatin; Time Factors | 1996 |
Effects of subcutaneous glucagon-like peptide 1 (GLP-1 [7-36 amide]) in patients with NIDDM.
Topics: Adult; Aged; Blood Glucose; C-Peptide; Cohort Studies; Diabetes Mellitus, Type 2; Fasting; Female; Gastric Emptying; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Injections, Subcutaneous; Insulin; Male; Middle Aged; Peptide Fragments; Peptides | 1996 |
Subcutaneous glucagon-like peptide I combined with insulin normalizes postcibal glycemic excursions in IDDM.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Drug Therapy, Combination; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Hypoglycemic Agents; Injections, Subcutaneous; Insulin; Male; Middle Aged; Pancreatic Polypeptide; Peptide Fragments; Time Factors | 1997 |
Acute incretin response to oral glucose is associated with stimulation of gastric inhibitory polypeptide, not glucagon-like peptide in young subjects.
Topics: Administration, Oral; Adolescent; Adult; C-Peptide; Gastric Inhibitory Polypeptide; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glucose Clamp Technique; Humans; Hyperglycemia; Peptide Fragments; Peptides; Secretory Rate; Stimulation, Chemical | 1997 |
Glucagon-like peptide-1 7-36 amide and peptide YY have additive inhibitory effect on gastric acid secretion in man.
Topics: Adult; Drug Interactions; Female; Gastric Acid; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Infusions, Intravenous; Male; Middle Aged; Neurotransmitter Agents; Pentagastrin; Peptide Fragments; Peptide YY; Peptides | 1997 |
Glucagon-like peptide 1 inhibition of gastric emptying outweighs its insulinotropic effects in healthy humans.
Topics: Adult; Blood Glucose; C-Peptide; Eating; Fasting; Gastric Emptying; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Infusions, Intravenous; Insulin; Insulin Secretion; Peptide Fragments; Peptides; Postprandial Period; Protein Precursors; Reference Values; Time Factors | 1997 |
Mechanisms of the antidiabetic action of subcutaneous glucagon-like peptide-1(7-36)amide in non-insulin dependent diabetes mellitus.
Topics: Aged; Blood Glucose; Breath Tests; Diabetes Mellitus, Type 2; Female; Gastric Emptying; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Tolerance Test; Humans; Injections, Subcutaneous; Insulin; Male; Middle Aged; Neurotransmitter Agents; Pancreatic Polypeptide; Peptide Fragments; Postprandial Period; Regression Analysis | 1998 |
Prolonged and enhanced secretion of glucagon-like peptide 1 (7-36 amide) after oral sucrose due to alpha-glucosidase inhibition (acarbose) in Type 2 diabetic patients.
Topics: Acarbose; Administration, Oral; Aged; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Female; Gastric Inhibitory Polypeptide; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Insulin; Male; Middle Aged; Peptide Fragments; Sucrose; Time Factors; Trisaccharides | 1998 |
Normalization of fasting glycaemia by intravenous GLP-1 ([7-36 amide] or [7-37]) in type 2 diabetic patients.
Topics: Age of Onset; Aged; Blood Glucose; C-Peptide; Calorimetry, Indirect; Cholesterol; Diabetes Mellitus, Type 2; Fasting; Fatty Acids, Nonesterified; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Infusions, Intravenous; Insulin; Insulin Secretion; Male; Middle Aged; Peptide Fragments; Peptides; Triglycerides | 1998 |
Subcutaneous glucagon-like peptide-1 (7-36) amide is insulinotropic and can cause hypoglycaemia in fasted healthy subjects.
Topics: Adult; Blood Glucose; Blood Pressure; Cross-Over Studies; Double-Blind Method; Fasting; Female; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Male; Peptide Fragments; Pulse | 1998 |
Differential effects of saturated and monounsaturated fatty acids on postprandial lipemia and incretin responses in healthy subjects.
Topics: Adult; Blood Glucose; Butter; Cholesterol, HDL; Diet; Dietary Fats; Fatty Acids; Fatty Acids, Monounsaturated; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Male; Neurotransmitter Agents; Olive Oil; Peptide Fragments; Peptides; Plant Oils; Postprandial Period; Triglycerides | 1999 |
Octreotide suppresses the incretin glucagon-like peptide (7-36) amide in patients with acromegaly or clinically nonfunctioning pituitary tumors and in healthy subjects.
Topics: Acromegaly; Adenoma; Adult; Antineoplastic Agents, Hormonal; Blood Glucose; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Tolerance Test; Hormones; Human Growth Hormone; Humans; Insulin; Male; Middle Aged; Octreotide; Peptide Fragments; Pituitary Neoplasms; Prospective Studies; Protein Precursors | 1999 |
Continuous subcutaneous infusion of glucagon-like peptide 1 lowers plasma glucose and reduces appetite in type 2 diabetic patients.
Topics: Adult; Aged; Appetite; Appetite Depressants; Blood Glucose; Blood Pressure; C-Peptide; Diabetes Mellitus, Type 2; Drug Delivery Systems; Energy Intake; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Hypoglycemic Agents; Infusion Pumps; Insulin; Lipids; Middle Aged; Peptide Fragments; Peptides; Pilot Projects; Postprandial Period; Protein Precursors | 1999 |
Effect of glucagon-like peptide 1(7-36)amide in insulin-treated patients with diabetes mellitus secondary to chronic pancreatitis.
Topics: Aged; Blood Glucose; C-Peptide; Chronic Disease; Diabetes Mellitus; Drug Therapy, Combination; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glycated Hemoglobin; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Middle Aged; Pancreatitis; Peptide Fragments | 2000 |
A novel hyperglycaemic clamp for characterization of islet function in humans: assessment of three different secretagogues, maximal insulin response and reproducibility.
Topics: Adult; Arginine; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glucose Clamp Technique; Humans; Hyperglycemia; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Male; Peptide Fragments; Protein Precursors; Reproducibility of Results | 2000 |
Effect of glucagon-like peptide 1(7-36) amide on glucose effectiveness and insulin action in people with type 2 diabetes.
Topics: Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Food; Gastric Emptying; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Human Growth Hormone; Humans; Hydrocortisone; Insulin; Kinetics; Peptide Fragments; Somatostatin | 2000 |
Effect of nutrient ingestion on glucagon-like peptide 1 (7-36 amide) secretion in human type 1 and type 2 diabetes.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Eating; Female; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Male; Middle Aged; Peptide Fragments; Radioimmunoassay | 2000 |
Circulating levels of incretin hormones and amylin in the fasting state and after oral glucose in GH-deficient patients before and after GH replacement: a placebo-controlled study.
Topics: Adult; Amyloid; Fasting; Female; Gastric Inhibitory Polypeptide; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glucose Tolerance Test; Growth Hormone; Hormone Replacement Therapy; Human Growth Hormone; Humans; Islet Amyloid Polypeptide; Male; Peptide Fragments; Protein Precursors | 2000 |
Effect of metformin on glucagon-like peptide 1 (GLP-1) and leptin levels in obese nondiabetic subjects.
Topics: Adolescent; Adult; Blood Glucose; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Clamp Technique; Humans; Hypoglycemic Agents; Leptin; Male; Metformin; Middle Aged; Obesity; Peptide Fragments; Peptides | 2001 |
Additive glucose-lowering effects of glucagon-like peptide-1 and metformin in type 2 diabetes.
Topics: Blood Glucose; C-Peptide; Cross-Over Studies; Diabetes Mellitus, Type 2; Drug Administration Schedule; Drug Therapy, Combination; Female; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glycated Hemoglobin; Humans; Infusions, Parenteral; Insulin; Insulin Secretion; Kinetics; Male; Metformin; Middle Aged; Peptide Fragments; Placebos; Research Design | 2001 |
Impaired incretin response after a mixed meal is associated with insulin resistance in nondiabetic men.
Topics: Adult; Biomarkers; Blood Glucose; Blood Pressure; Body Weight; Eating; Gastric Inhibitory Polypeptide; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Clamp Technique; Humans; Insulin; Insulin Resistance; Male; Middle Aged; Peptide Fragments; Postprandial Period; Protein Precursors; Regression Analysis | 2001 |
Postprandial glucose, insulin, and incretin responses to grain products in healthy subjects.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Blood Glucose; Bread; Dietary Fiber; Fasting; Female; Gastric Emptying; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Male; Neurotransmitter Agents; Peptide Fragments; Postprandial Period; Secale; Triticum | 2002 |
Men at increased risk of coronary heart disease are not different from age- and weight-matched healthy controls in their postprandial triglyceride, nonesterified fatty acid, or incretin responses to sucrose.
Topics: Blood Glucose; Case-Control Studies; Coronary Disease; Fatty Acids, Nonesterified; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Male; Peptide Fragments; Postprandial Period; Risk Factors; Sucrose; Triglycerides | 2002 |
Effects of glucagon-like peptide-1(7-36)amide on motility and sensation of the proximal stomach in humans.
Topics: Adult; Blood Glucose; Gastric Emptying; Gastric Fundus; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Male; Muscle Relaxation; Peptide Fragments; Pressure; Satiety Response | 2002 |
Impaired beta-cell function, incretin effect, and glucagon suppression in patients with type 1 diabetes who have normal fasting glucose.
Topics: Arginine; Autoantibodies; Blood Glucose; Diabetes Mellitus, Type 1; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Clamp Technique; Glucose Tolerance Test; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Peptide Fragments; Reference Values | 2002 |
Effect of glucagon-like peptide 1 (7-36 amide) on insulin-mediated glucose uptake in patients with type 1 diabetes.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Clamp Technique; Humans; Hyperinsulinism; Insulin; Liver; Male; Neurotransmitter Agents; Peptide Fragments; Peptides | 2003 |
Effect of lipase inhibition on gastric emptying of, and the glycemic and incretin responses to, an oil/aqueous drink in type 2 diabetes mellitus.
Topics: Autonomic Nervous System; Blood Glucose; Diabetes Mellitus, Type 2; Dietary Fats; Enzyme Inhibitors; Female; Gastric Emptying; Gastric Inhibitory Polypeptide; Gastric Mucosa; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Hemodynamics; Humans; Insulin; Lactones; Lipase; Male; Middle Aged; Orlistat; Peptide Fragments; Peptides | 2003 |
The pathophysiology of diabetes involves a defective amplification of the late-phase insulin response to glucose by glucose-dependent insulinotropic polypeptide-regardless of etiology and phenotype.
Topics: Adult; Aged; Blood Glucose; C-Peptide; Chronic Disease; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; DNA-Binding Proteins; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Hepatocyte Nuclear Factor 1; Hepatocyte Nuclear Factor 1-alpha; Hepatocyte Nuclear Factor 1-beta; Humans; Hyperglycemia; Insulin; Islets of Langerhans; Male; Middle Aged; Neurotransmitter Agents; Nuclear Proteins; Pancreatitis; Peptide Fragments; Phenotype; Protein Precursors; Transcription Factors | 2003 |
Recombinant glucagon-like peptide-1 (7-36 amide) lowers fasting serum glucose in a broad spectrum of patients with type 2 diabetes.
Topics: Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Fasting; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Hypoglycemic Agents; Insulin; Metformin; Peptide Fragments; Placebos; Recombinant Proteins; Sulfonylurea Compounds | 2003 |
Ethanol with a mixed meal decreases the incretin levels early postprandially and increases postprandial lipemia in type 2 diabetic patients.
Topics: Aged; Alcohol Drinking; Butter; Cholesterol; Cholesterol, HDL; Chylomicrons; Diabetes Mellitus, Type 2; Dietary Carbohydrates; Dietary Fats; Energy Intake; Ethanol; Fatty Acids; Fatty Acids, Nonesterified; Food; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Lipids; Middle Aged; Peptide Fragments; Protein Precursors; Triglycerides | 2004 |
Blood glucose control in healthy subject and patients receiving intravenous glucose infusion or total parenteral nutrition using glucagon-like peptide 1.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Fatty Acids; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Humans; Hyperglycemia; Infusions, Intravenous; Insulin; Male; Middle Aged; Parenteral Nutrition, Total; Peptide Fragments; Placebos | 2004 |
Effects of glucagon-like peptide-1 in patients with acute myocardial infarction and left ventricular dysfunction after successful reperfusion.
Topics: Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Blood Glucose; Combined Modality Therapy; Diabetes Complications; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Male; Middle Aged; Myocardial Infarction; Peptide Fragments; Pilot Projects; Safety; Stroke Volume; Treatment Outcome; Ventricular Function, Left | 2004 |
Orally administered glucagon-like peptide-1 affects glucose homeostasis following an oral glucose tolerance test in healthy male subjects.
Topics: Administration, Oral; Adult; Appetite; Blood Glucose; Caprylates; Cross-Over Studies; Double-Blind Method; Drug Carriers; Gastric Emptying; Glucagon; Glucagon-Like Peptide 1; Glucose Tolerance Test; Homeostasis; Human Growth Hormone; Humans; Incretins; Insulin; Intestinal Absorption; Male; Peptide Fragments; Postprandial Period; Reference Values; Young Adult | 2009 |
Pharmacokinetics and pharmacodynamics of inhaled GLP-1 (MKC253): proof-of-concept studies in healthy normal volunteers and in patients with type 2 diabetes.
Topics: Administration, Inhalation; Adult; Aged; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Delivery Systems; Energy Intake; Female; Glucagon; Glucagon-Like Peptide 1; Humans; Hypoglycemic Agents; Insulin; Male; Middle Aged; Peptide Fragments | 2010 |
Does GLP-1 suppress its own basal secretion?
Topics: Adult; Basal Metabolism; Blood Glucose; Feedback, Physiological; Female; Glucagon; Glucagon-Like Peptide 1; Humans; Insulin; Male; Obesity; Peptide Fragments; Peptides; Thinness | 2016 |
255 other study(ies) available for glucagon and glucagon-like peptide 1 (7-36)amide
| Article | Year |
|---|---|
The enteroinsular axis.
Topics: Animals; Digestive System Physiological Phenomena; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Islets of Langerhans; Peptide Fragments; Peptides; Rats | 1978 |
Antidiabetogenic effect of glucagon-like peptide-1 (7-36)amide in normal subjects and patients with diabetes mellitus.
Topics: Adult; Aged; Blood Glucose; C-Peptide; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Eating; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Insulin Infusion Systems; Insulin Secretion; Male; Middle Aged; Obesity; Peptide Fragments; Peptides; Somatostatin | 1992 |
Comparison of the insulinotropic activity of glucagon-superfamily peptides in rat pancreas perfusion.
Topics: Amino Acid Sequence; Animals; Dose-Response Relationship, Drug; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Growth Hormone-Releasing Hormone; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Molecular Sequence Data; Peptide Fragments; Rats; Rats, Wistar; Sequence Homology, Amino Acid; Vasoactive Intestinal Peptide | 1992 |
The enteroinsular axis revisited. A novel role for an incretin.
Topics: Blood Glucose; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Insulin Secretion; Peptide Fragments; Peptides | 1992 |
Comparison of the effect of GIP and GLP-1 (7-36amide) on insulin release from rat pancreatic islets.
Topics: Animals; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Peptide Fragments; Peptides; Rats; Rats, Inbred Strains | 1992 |
[A case of hyperinsulinemia due to hypersecretion of incretin].
Topics: Aged; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Tolerance Test; Humans; Hyperinsulinism; Insulin; Insulin Secretion; Male; Peptide Fragments; Protein Precursors | 1992 |
Endocrine response to intragastric and intravenous glucose challenge in the denervated dog pancreas.
Topics: Animals; Blood Glucose; Denervation; Dogs; Gastric Inhibitory Polypeptide; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glucose Tolerance Test; Injections, Intravenous; Insulin; Insulin Secretion; Islets of Langerhans; Pancreas; Pancreas Transplantation; Pancreatic Polypeptide; Peptide Fragments; Transplantation, Autologous | 1992 |
Glucagonlike peptide-I-(7-36)-amide receptors only in islets of Langerhans. Autoradiographic survey of extracerebral tissues in rats.
Topics: Animals; Autoradiography; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Iodine Radioisotopes; Islets of Langerhans; Male; Peptide Fragments; Peptides; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Glucagon; Stomach | 1991 |
Developmental patterns of glucagon-like peptide-1-(7-36) amide and peptide-YY in rat pancreas and gut.
Topics: Aging; Animals; Animals, Newborn; Chromatography, Gel; Fetus; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Insulin; Intestinal Mucosa; Intestines; Pancreas; Peptide Fragments; Peptide YY; Peptides; Radioimmunoassay; Rats; Rats, Inbred Strains; Somatostatin | 1991 |
Interaction of glucagon-like peptide-1 (7-36)amide and cholecystokinin-8 in the endocrine and exocrine rat pancreas.
Topics: Amylases; Animals; Drug Synergism; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; In Vitro Techniques; Islets of Langerhans; Male; Pancreas; Peptide Fragments; Peptides; Rats; Rats, Inbred Strains; Sincalide | 1990 |
Priming effect of glucagon-like peptide-1 (7-36) amide, glucose-dependent insulinotropic polypeptide and cholecystokinin-8 at the isolated perfused rat pancreas.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Line; Colforsin; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; In Vitro Techniques; Islets of Langerhans; Kinetics; Male; Peptide Fragments; Peptides; Perfusion; Rats; Rats, Inbred Strains; Sincalide | 1991 |
Hyperglycaemia but not hyperinsulinaemia prevents the secretion of glucagon-like peptide-1 (7-36 amide) stimulated by fat ingestion.
Topics: Adult; Analysis of Variance; Blood Glucose; Chromatography, Gel; Dietary Fats; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Hyperglycemia; Injections, Intravenous; Insulin; Peptide Fragments; Peptides | 1991 |
GLP-1(7-36) amide stimulates insulin secretion in rat islets: studies on the mode of action.
Topics: Alkaloids; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Peptide Fragments; Peptides; Protein Kinase C; Rats; Rats, Inbred Strains; Staurosporine | 1991 |
Characterization of glucagon-like peptide-I(7-36)amide receptors of rat lung membranes by covalent cross-linking.
Topics: Animals; Cell Membrane; Cells, Cultured; Cross-Linking Reagents; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Ligands; Lung; Molecular Weight; Peptide Fragments; Peptides; Rats; Receptors, Cell Surface; Receptors, Glucagon; Succinimides | 1991 |
GLP-1(7-36)amide-stimulated insulin secretion in rat islets is sodium-dependent.
Topics: Animals; Calcium; Cells, Cultured; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Peptide Fragments; Peptides; Rats; Rats, Inbred Strains; Rubidium; Sodium | 1991 |
GLP-1 and GLP-1(7-36) amide: influences on basal and stimulated insulin and glucagon secretion in the mouse.
Topics: Animals; Blood Glucose; Carbachol; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Immunohistochemistry; Insulin; Insulin Secretion; Intestines; Mice; Mice, Inbred Strains; Pancreas; Peptide Fragments; Peptides; Protein Precursors; Reference Values; Sincalide | 1991 |
Effect of the entero-pancreatic hormones, gastric inhibitory polypeptide and glucagon-like polypeptide-1(7-36) amide, on fatty acid synthesis in explants of rat adipose tissue.
Topics: Adipose Tissue; Animals; Culture Techniques; Fatty Acids; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Insulin; Male; Neuropeptides; Peptide Fragments; Peptides; Rats | 1991 |
Gut signals for islet hormone release.
Topics: Animals; Cholecystokinin; Digestive System Physiological Phenomena; Gastric Emptying; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Islets of Langerhans; Peptide Fragments; Peptides; Protein Precursors; Rats | 1990 |
Reduced insulinotropic effects of glucagonlike peptide I-(7-36)-amide and gastric inhibitory polypeptide in isolated perfused diabetic rat pancreas.
Topics: Animals; Animals, Newborn; Blood Glucose; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Insulin; Pancreas; Peptide Fragments; Peptides; Perfusion; Rats; Rats, Inbred Strains; Streptozocin | 1990 |
Characterization of receptors for glucagon-like peptide-1(7-36)amide on rat lung membranes.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Kinetics; Lung; Male; Peptide Fragments; Peptides; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Glucagon | 1990 |
Dexamethasone pretreatment of rat insulinoma cells decreases binding of glucagon-like peptide-1(7-36)amide.
Topics: Animals; Cyclic AMP; Dexamethasone; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucocorticoids; Insulinoma; Mifepristone; Pancreatic Neoplasms; Peptide Fragments; Peptides; Protein Binding; Rats; Time Factors; Tumor Cells, Cultured | 1990 |
Suppression of synthesis and release of glucagon by glucagon-like peptide-1 (7-36 amide) without affect on mRNA level in isolated rat islets.
Topics: Animals; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; In Vitro Techniques; Islets of Langerhans; Kinetics; Male; Peptide Fragments; Peptides; Proglucagon; Protein Precursors; Rats; Rats, Inbred Strains; RNA, Messenger | 1990 |
Comparison of GLP-1 (7-36amide) and GIP on release of somatostatin-like immunoreactivity and insulin from the isolated rat pancreas.
Topics: Animals; Blood Glucose; Dose-Response Relationship, Drug; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Insulin; Pancreas; Peptide Fragments; Peptides; Perfusion; Rats | 1990 |
Effects of truncated glucagon-like peptide-1 on pancreatic hormone release in normal conscious dogs.
Topics: Animals; Blood Glucose; Dogs; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Insulin; Kinetics; Pancreatic Hormones; Peptide Fragments; Peptides | 1990 |
[Digestive tract hormones and pancreatic secretion].
Topics: Animals; Arginine; Blood Glucose; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Insulin Secretion; Intestines; Mice; Pancreatic Hormones; Peptide Fragments; Peptides; Protein Precursors; Rats; Sincalide | 1990 |
Glucagon-like peptide-1 (7-36)-NH2: a physiological inhibitor of gastric acid secretion in man.
Topics: Adult; Depression, Chemical; Female; Gastric Acid; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Male; Pentagastrin; Peptide Fragments; Peptides; Secretory Rate; Time Factors | 1990 |
Signal transmission after GLP-1(7-36)amide binding in RINm5F cells.
Topics: Adenoma, Islet Cell; Animals; Calcium; Cell Line; Cell Membrane; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Insulinoma; Membrane Potentials; Peptide Fragments; Peptides; Rats; Signal Transduction; Tumor Cells, Cultured | 1989 |
Interaction of glucagon-like peptide-1(7-36)amide and somatostatin-14 in RINm5F cells and in the perfused rat pancreas.
Topics: Adenoma, Islet Cell; Animals; Cell Line; Cyclic AMP; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Insulin; Insulinoma; Male; Pancreas; Peptide Fragments; Peptides; Rats; Somatostatin; Tumor Cells, Cultured | 1989 |
Glucagonlike peptide I (7-37) actions on endocrine pancreas.
Topics: Animals; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Peptide Fragments; Peptides; Rats | 1989 |
Glucagonostatic and insulinotropic action of glucagonlike peptide I-(7-36)-amide.
Topics: Animals; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Insulin; Male; Pancreas; Peptide Fragments; Peptides; Rats; Rats, Inbred Strains | 1989 |
Synergistic stimulatory effect of glucagon-like peptide-1 (7-36) amide and glucose-dependent insulin-releasing polypeptide on the endocrine rat pancreas.
Topics: Animals; Drug Synergism; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Peptide Fragments; Peptides; Rats; Rats, Inbred Strains; Stimulation, Chemical | 1989 |
Comparison of the effects of various C-terminal and N-terminal fragment peptides of glucagon-like peptide-1 on insulin and glucagon release from the isolated perfused rat pancreas.
Topics: Animals; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Histidine; Insulin; Insulin Secretion; Male; Pancreas; Peptide Fragments; Peptides; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1989 |
Identification of glucagon-like peptide-1(7-36) amide in rat brain.
Topics: Animals; Brain Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Male; Peptide Fragments; Peptides; Radioimmunoassay; Rats; Rats, Inbred Strains | 1989 |
Characterization of glucagon-like peptide-1-(7-36)amide in the hypothalamus.
Topics: Animals; Diabetes Mellitus, Experimental; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Hypothalamus; Immunohistochemistry; Peptide Fragments; Peptides; Rats; Rats, Inbred Strains | 1989 |
Receptors for glucagon-like peptide-1(7-36) amide on rat insulinoma-derived cells.
Topics: Adenoma, Islet Cell; Animals; Binding, Competitive; Cell Line; Cyclic AMP; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Insulinoma; Intestinal Mucosa; Jejunum; Pancreatic Neoplasms; Peptide Fragments; Peptides; Rats; Receptors, Cell Surface; Receptors, Glucagon | 1988 |
Identification and characterization of glucagon-like peptide-1 7-36 amide-binding sites in the rat brain and lung.
Topics: Animals; Binding, Competitive; Brain; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Kinetics; Lung; Organ Specificity; Peptide Fragments; Peptides; Rats; Rats, Inbred Strains; Receptors, Gastrointestinal Hormone; Receptors, Glucagon | 1988 |
Absence of the "incretin" phenomenon in the autotransplanted human pancreas.
Topics: Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Insulin Secretion; Middle Aged; Pancreas; Pancreas Transplantation; Peptide Fragments; Transplantation, Autologous | 1988 |
Glucagon-like peptide-1 (7-36 amide): a potent glucagonostatic and insulinotropic hormone.
Topics: Animals; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Insulin; Insulin Secretion; Islets of Langerhans; Male; Peptide Fragments; Peptides; Perfusion; Rats; Rats, Inbred Strains; Reference Values | 1988 |
Isolation and characterisation of GLP-1 7-36 amide from rat intestine. Elevated levels in diabetic rats.
Topics: Animals; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Colon; Diabetes Mellitus, Experimental; Eating; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Ileum; Intestinal Mucosa; Intestines; Mass Spectrometry; Molecular Weight; Peptide Fragments; Peptides; Rats; Rats, Inbred Strains; Tissue Distribution | 1988 |
Effects of intraduodenal nutrient infusion on insulin response to subsequent intravenous glucose in rats.
Topics: Administration, Oral; Animals; Blood Glucose; Duodenum; Femoral Vein; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Infusions, Intravenous; Injections; Insulin; Insulin Secretion; Male; Peptide Fragments; Portal Vein; Rats; Rats, Inbred Strains | 1987 |
Trophic effect of glucagon-(1-21)-peptide on the isolated rat ileal mucosal cells.
Topics: Amino Acid Sequence; Animals; Cell Division; Dose-Response Relationship, Drug; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Ileum; Intestinal Mucosa; Male; Peptide Fragments; Peptides; Rats; Rats, Inbred Strains; Thymidine | 1988 |
Gastrointestinal peptides and insulin secretion.
Topics: Animals; Gastric Inhibitory Polypeptide; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Insulin Secretion; Liver; Neuropeptides; Obesity; Peptide Fragments | 1987 |
The effects of exercise on plasma insulin.
Topics: Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Liver; Muscles; Peptide Fragments; Peptides; Physical Education and Training; Physical Exertion; Receptors, Adrenergic, alpha | 1981 |
Preservation of incretin activity after removal of gastric inhibitory polypeptide (GIP) from rat gut extracts by immunoadsorption.
Topics: Animals; Antibodies; Gastric Inhibitory Polypeptide; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Immunosorbent Techniques; Infusions, Parenteral; Insulin; Insulin Secretion; Intestinal Mucosa; Male; Peptide Fragments; Peptides; Rats; Rats, Inbred Strains; Time Factors; Tissue Extracts | 1983 |
Partial purification of an insulin-releasing activity in human serum.
Topics: Animals; Biological Assay; Child; Chromatography, High Pressure Liquid; Fasting; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Tolerance Test; Humans; In Vitro Techniques; Intercellular Signaling Peptides and Proteins; Islets of Langerhans; Obesity; Peptide Fragments; Peptides; Rats; Rats, Inbred Strains | 1983 |
[Gastric inhibitory polypeptide (GIP), incretin and gastrointestinal diseases].
Topics: Gastric Inhibitory Polypeptide; Gastrointestinal Diseases; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Peptide Fragments; Peptides; Radioimmunoassay | 1984 |
Gastric inhibitory polypeptide and insulin release in response to oral and intravenous glucose in coeliac disease.
Topics: Adult; Blood Glucose; Celiac Disease; Female; Gastric Inhibitory Polypeptide; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Tolerance Test; Humans; Insulin; Insulin Secretion; Male; Middle Aged; Peptide Fragments; Peptides | 1982 |
The broadening incretin concept.
Topics: Blood Glucose; Food; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Insulin Secretion; Peptide Fragments; Peptides | 1980 |
Signal transduction of the GLP-1-receptor cloned from a human insulinoma.
Topics: Amino Acid Sequence; Animals; Blotting, Northern; Calcium; Cell Line; Cloning, Molecular; Cyclic AMP; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulinoma; Molecular Sequence Data; Peptide Fragments; Rats; Receptors, Glucagon; Recombinant Proteins; RNA; Sequence Homology, Amino Acid; Signal Transduction; Transfection | 1994 |
Failure of GLP-1(7-36)amide to affect glycogenesis in rat skeletal muscle.
Topics: Animals; Biological Transport; Carbon Dioxide; Deoxyglucose; Dose-Response Relationship, Drug; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glycogen; In Vitro Techniques; Insulin; Lactates; Male; Muscle, Skeletal; Peptide Fragments; Rats; Rats, Sprague-Dawley | 1995 |
Stimulation of cloned human glucagon-like peptide 1 receptor expressed in HEK 293 cells induces cAMP-dependent activation of calcium-induced calcium release.
Topics: Acetylcholine; Calcium; Calcium Channel Blockers; Cell Line; Cloning, Molecular; Cyclic AMP; Embryo, Mammalian; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Humans; Ionomycin; Kidney; Peptide Fragments; Receptors, Glucagon; Recombinant Proteins; Ryanodine; Thionucleotides | 1995 |
Insulinotropic actions of intravenous glucagon-like peptide-1 (GLP-1) [7-36 amide] in the fasting state in healthy subjects.
Topics: Adult; Analysis of Variance; C-Peptide; Dose-Response Relationship, Drug; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Infusions, Intravenous; Insulin; Insulin Secretion; Kinetics; Male; Peptide Fragments; Reference Values; Time Factors | 1995 |
Both subcutaneously and intravenously administered glucagon-like peptide I are rapidly degraded from the NH2-terminus in type II diabetic patients and in healthy subjects.
Topics: Adult; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Enzyme-Linked Immunosorbent Assay; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Infusions, Intravenous; Injections, Subcutaneous; Male; Middle Aged; Peptide Fragments; Radioimmunoassay; Reference Values; Sensitivity and Specificity; Time Factors | 1995 |
Amylin alters the biological action of the incretin hormone GLP-1(7-36)amide.
Topics: Adenylyl Cyclases; Amyloid; Animals; Cell Line; Colforsin; Cyclic AMP; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Intolerance; Insulinoma; Islet Amyloid Polypeptide; Islets of Langerhans; Models, Biological; Peptide Fragments; Peptides; Rats; Substance P | 1993 |
Insulin secretion and plasma levels of glucose-dependent insulinotropic peptide and glucagon-like peptide 1 [7-36 amide] after oral glucose in cirrhosis.
Topics: Adult; Blood Glucose; C-Peptide; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Humans; Insulin; Insulin Secretion; Liver Cirrhosis; Male; Middle Aged; Peptide Fragments | 1995 |
Effects of glucose-dependent insulinotropic polypeptide and glucagon-like peptide-I-(7-36) on insulin secretion.
Topics: Animals; Chromatography, High Pressure Liquid; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Male; Pancreas; Peptide Fragments; Rats; Rats, Wistar; Swine | 1995 |
Glucagon-like peptide-1 and glucose-dependent insulin-releasing polypeptide plasma levels in response to nutrients.
Topics: Adult; Amino Acids; Animals; Diet; Fats; Food; Galactose; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Humans; Insulin; Insulin Secretion; Male; Peptide Fragments; Peptides; Protein Precursors; Rats; Rats, Wistar | 1995 |
Comparative effects of GLP-1-(7-36) amide, oxyntomodulin and glucagon on rabbit gastric parietal cell function.
Topics: Aminopyrine; Animals; Blotting, Northern; Cyclic AMP; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Histamine; Oxyntomodulin; Parietal Cells, Gastric; Peptide Fragments; Rabbits; RNA, Messenger; Somatostatin | 1995 |
Glucagon-like peptide-1 binding to rat skeletal muscle.
Topics: Adenylyl Cyclases; Animals; Binding, Competitive; Cell Membrane; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Insulin; Muscle, Skeletal; Peptide Fragments; Protein Precursors; Rats; Rats, Wistar; Receptor, Insulin; Receptors, Glucagon | 1995 |
Glucagon-like peptide I increases cytoplasmic calcium in insulin-secreting beta TC3-cells by enhancement of intracellular calcium mobilization.
Topics: Animals; Calcium; Calcium Channels; Cell Line; Colforsin; Cyclic AMP; Cytoplasm; Dose-Response Relationship, Drug; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Inositol Phosphates; Insulin; Insulin Secretion; Insulinoma; Islets of Langerhans; Kinetics; Mice; Mice, Transgenic; Pancreatic Neoplasms; Peptide Fragments; Ryanodine; Time Factors; Tumor Cells, Cultured | 1995 |
Reduction of the incretin effect in rats by the glucagon-like peptide 1 receptor antagonist exendin (9-39) amide.
Topics: Animals; Drug Interactions; Exenatide; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Glucose; Insulin; Male; Peptide Fragments; Peptides; Protein Precursors; Radioimmunoassay; Rats; Rats, Wistar; Receptors, Glucagon; Venoms | 1995 |
Glucagon-like peptide-1 (GLP-1): a piece of the incretin puzzle.
Topics: Animals; Diabetes Mellitus, Type 2; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Peptide Fragments; Peptides; Protein Precursors; Rodentia | 1995 |
Glucagon-like peptide-1 is a physiological incretin in rat.
Topics: Anesthesia; Animals; Arginine; Cells, Cultured; Consciousness; Eating; Fasting; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Glucose; Infusions, Intravenous; Insulin; Insulin Secretion; Male; Pancreas; Peptide Fragments; Peptides; Protein Precursors; Radioligand Assay; Rats; Rats, Wistar; Receptors, Glucagon; Vasoactive Intestinal Peptide | 1995 |
Glucagon-like peptide-1 (7-36)amide and glucose-dependent insulinotropic polypeptide secretion in response to nutrient ingestion in man: acute post-prandial and 24-h secretion patterns.
Topics: Adult; Blood Glucose; Circadian Rhythm; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; Eating; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Humans; Insulin; Lipid Metabolism; Nutritional Physiological Phenomena; Peptide Fragments; Radioimmunoassay; Time Factors | 1993 |
Glucagon-like peptide-1 modulates Ca2+ current but not K+ATP current in intact mouse pancreatic B-cells.
Topics: Adenosine Triphosphate; Animals; Calcium Channels; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; In Vitro Techniques; Islets of Langerhans; Kinetics; Membrane Potentials; Mice; Mice, Inbred Strains; Peptide Fragments; Peptides; Potassium Channels; Protein Precursors | 1995 |
Investigations into the actions of glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1(7-36)amide on lipoprotein lipase activity in explants of rat adipose tissue.
Topics: Adipose Tissue; Animals; Culture Techniques; Dactinomycin; Enzyme Activation; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Insulin; Lipoprotein Lipase; Male; Peptide Fragments; Rats; Rats, Wistar | 1995 |
Potent glycogenic effect of GLP-1(7-36)amide in rat skeletal muscle.
Topics: Animals; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glycogen; Glycogen Synthase; Insulin; Lactates; Lactic Acid; Muscle, Skeletal; Neurotransmitter Agents; Peptide Fragments; Phosphorylase a; Rats; Rats, Wistar | 1994 |
Gastric inhibitory polypeptide and glucagon-like peptide-1(7-36) amide exert similar effects on somatostatin secretion but opposite effects on gastrin secretion from the rat stomach.
Topics: Animals; Gastric Inhibitory Polypeptide; Gastric Mucosa; Gastrins; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; In Vitro Techniques; Male; Peptide Fragments; Peptides; Rats; Rats, Wistar; Swine | 1994 |
Rat gastric somatostatin and gastrin release: interactions of exendin-4 and truncated glucagon-like peptide-1 (GLP-1) amide.
Topics: Animals; Exenatide; Gastric Juice; Gastrins; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; In Vitro Techniques; Male; Peptide Fragments; Peptides; Rats; Rats, Sprague-Dawley; Somatostatin; Venoms | 1994 |
Stable expression of the rat GLP-I receptor in CHO cells: activation and binding characteristics utilizing GLP-I(7-36)-amide, oxyntomodulin, exendin-4, and exendin(9-39).
Topics: Animals; CHO Cells; Cricetinae; Evaluation Studies as Topic; Exenatide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Lizards; Neurotransmitter Agents; Oxyntomodulin; Peptide Fragments; Peptides; Rats; Receptors, Cell Surface; Receptors, Glucagon; Venoms | 1994 |
Glycosylation of the GLP-1 receptor is a prerequisite for regular receptor function.
Topics: Amidohydrolases; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Glycosylation; Insulin; Insulin Secretion; Islets of Langerhans; Molecular Weight; Peptide Fragments; Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase; Receptors, Cell Surface; Receptors, Glucagon; Tumor Cells, Cultured; Tunicamycin | 1994 |
Rat parietal cell receptors for GLP-1-(7-36) amide: northern blot, cross-linking, and radioligand binding.
Topics: Aminopyrine; Animals; Blotting, Northern; Cell Separation; Cross-Linking Reagents; Exenatide; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Kinetics; Parietal Cells, Gastric; Peptide Fragments; Peptides; Radioligand Assay; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, Glucagon; RNA, Messenger; Venoms | 1994 |
Regulation of glucagon-like peptide-1-(7-36) amide secretion by intestinal neurotransmitters and hormones in the isolated vascularly perfused rat colon.
Topics: Animals; Colon; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; In Vitro Techniques; Intestinal Mucosa; Male; Neuropeptides; Neurotransmitter Agents; Peptide Fragments; Perfusion; Rats; Rats, Wistar | 1994 |
Glucose-dependent alterations of intracellular free calcium by glucagon-like peptide-1(7-36amide) in individual ob/ob mouse beta-cells.
Topics: Animals; Calcium; Cyclic AMP; Diabetes Mellitus, Type 2; Felodipine; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; In Vitro Techniques; Islets of Langerhans; Mice; Mice, Inbred C57BL; Peptide Fragments | 1994 |
Dipeptidyl-peptidase IV hydrolyses gastric inhibitory polypeptide, glucagon-like peptide-1(7-36)amide, peptide histidine methionine and is responsible for their degradation in human serum.
Topics: Amino Acid Sequence; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Male; Models, Biological; Molecular Sequence Data; Peptide Fragments; Peptide PHI; Substrate Specificity | 1993 |
Glucagon-like peptide-1-(7-36) amide, oxyntomodulin, and glucagon interact with a common receptor in a somatostatin-secreting cell line.
Topics: Animals; Binding, Competitive; Blotting, Northern; Cell Line; Cell Membrane; Cricetinae; Cross-Linking Reagents; Cyclic AMP; Fibroblasts; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Oxyntomodulin; Peptide Fragments; Receptors, Cell Surface; Receptors, Glucagon; Somatostatin; Transfection | 1993 |
Detection of the human glucagon-like peptide 1(7-36) amide receptor on insulinoma-derived cell membranes.
Topics: Animals; Cell Membrane; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Humans; Insulinoma; Islets of Langerhans; Pancreatic Neoplasms; Peptide Fragments; Rats; Receptors, Cell Surface; Receptors, Glucagon; Tumor Cells, Cultured | 1994 |
Structure-activity relationships of glucagon-like peptide-1(7-36)amide: insulinotropic activities in perfused rat pancreases, and receptor binding and cyclic AMP production in RINm5F cells.
Topics: Animals; Cell Line; Cyclic AMP; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Insulin; Insulinoma; Male; Pancreas; Peptide Fragments; Perfusion; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, Glucagon; Stimulation, Chemical; Structure-Activity Relationship | 1994 |
Changes in arterial blood pressure and heart rate induced by glucagon-like peptide-1-(7-36) amide in rats.
Topics: Animals; Blood Pressure; Catecholamines; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Heart Rate; Male; Peptide Fragments; Peptides; Rats; Rats, Sprague-Dawley; Reserpine | 1994 |
Glucagon-like peptide 1 enhances glucose tolerance both by stimulation of insulin release and by increasing insulin-independent glucose disposal.
Topics: Adult; Blood Glucose; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Tolerance Test; Humans; Infusions, Intravenous; Insulin; Male; Middle Aged; Peptide Fragments | 1994 |
Presence of glucagon and glucagon-like peptide-1-(7-36)amide receptors in solubilized membranes of human adipose tissue.
Topics: Adipose Tissue; Aged; Cell Membrane; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Humans; Male; Middle Aged; Peptide Fragments; Receptors, Cell Surface; Receptors, Glucagon | 1993 |
Effects of glucagon like peptide-1(7-36) amide on the cytoplasmic Ca(2+)-concentration in rat islet cells.
Topics: Animals; Calcium; Cytoplasm; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Islets of Langerhans; Male; Peptide Fragments; Rats; Rats, Sprague-Dawley; Spectrometry, Fluorescence | 1993 |
Glucose dependent insulinotropic polypeptide and glucagon-like peptide-1(7-36)amide: effects on lipoprotein lipase activity.
Topics: Adipose Tissue; Animals; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Insulin; Lipoprotein Lipase; Peptide Fragments; Rats | 1993 |
Presence and characterization of glucagon-like peptide-1(7-36) amide receptors in solubilized membranes of rat adipose tissue.
Topics: Adipose Tissue; Animals; Binding, Competitive; Cell Membrane; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Kinetics; Male; Peptide Fragments; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, Glucagon; Solubility; Temperature | 1993 |
Solubilization of active receptors for glucagon-like peptide-1(7-36)amide from rat lung membranes.
Topics: Animals; Cations; Cell Membrane; Cross-Linking Reagents; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Guanine Nucleotides; Hydrogen-Ion Concentration; Lung; Male; Peptide Fragments; Rats; Receptors, Cell Surface; Receptors, Glucagon; Solubility | 1993 |
Possible role of the adrenergic mechanism in gastric inhibitory polypeptide- and glucagon-like peptide-1 (7-36) amide-induced insulin release in the rat.
Topics: Animals; Blood Glucose; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Insulin; Insulin Secretion; Male; Peptide Fragments; Propranolol; Rats; Rats, Wistar; Receptors, Adrenergic, beta | 1993 |
Neuropeptide Y expression and regulation in a differentiated rat insulin-secreting cell line.
Topics: Adenylyl Cyclases; Animals; Cell Differentiation; Clonidine; Colforsin; Cyclic AMP; Enzyme Activation; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation, Neoplastic; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Insulin; Insulin Secretion; Insulinoma; Neuropeptide Y; Pancreatic Neoplasms; Peptide Fragments; Protein Kinase C; Rats; Receptors, Neuropeptide Y; Tumor Cells, Cultured | 1993 |
Exendin-4 is a high potency agonist and truncated exendin-(9-39)-amide an antagonist at the glucagon-like peptide 1-(7-36)-amide receptor of insulin-secreting beta-cells.
Topics: Animals; Binding, Competitive; Cell Line; Cell Membrane; Cyclic AMP; Exenatide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Insulin; Insulin Secretion; Insulinoma; Kinetics; Lizards; Lung; Pancreatic Neoplasms; Peptide Fragments; Peptides; Rats; Receptors, Cell Surface; Receptors, Glucagon; Tumor Cells, Cultured; Venoms | 1993 |
Glucagon-like peptide-1-(7-36)amide and a rise in cyclic adenosine 3',5'-monophosphate increase cytosolic free Ca2+ in rat pancreatic beta-cells by enhancing Ca2+ channel activity.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Cyclic AMP; Cytosol; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Islets of Langerhans; Nitrendipine; Osmolar Concentration; Peptide Fragments; Rats | 1993 |
Biological effects and metabolic rates of glucagonlike peptide-1 7-36 amide and glucagonlike peptide-1 7-37 in healthy subjects are indistinguishable.
Topics: Adult; Blood Glucose; C-Peptide; Fatty Acids, Nonesterified; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Insulin Secretion; Male; Peptide Fragments; Structure-Activity Relationship; Time Factors | 1993 |
A role for glucagon-like peptide-1 in the central regulation of feeding.
Topics: Animals; Cerebral Ventricles; Eating; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Injections, Intraventricular; Male; Neuropeptide Y; Peptide Fragments; Proto-Oncogene Proteins c-fos; Rats; Satiation | 1996 |
Glycemic control mechanisms after canine islet autografting.
Topics: Animals; Blood Glucose; Dogs; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Tolerance Test; Insulin; Insulin Secretion; Islets of Langerhans Transplantation; Pancreatectomy; Peptide Fragments; Transplantation, Autologous | 1995 |
Dose-responses for the slowing of gastric emptying in a rodent model by glucagon-like peptide (7-36) NH2, amylin, cholecystokinin, and other possible regulators of nutrient uptake.
Topics: Amino Acids; Amyloid; Animals; Cholecystokinin; Dose-Response Relationship, Drug; Gastric Emptying; Gastric Inhibitory Polypeptide; Gastrointestinal Hormones; Gels; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Islet Amyloid Polypeptide; Male; Pancreatic Polypeptide; Peptide Fragments; Phenolsulfonphthalein; Rats; Rats, Sprague-Dawley | 1996 |
Elimination of the action of glucagon-like peptide 1 causes an impairment of glucose tolerance after nutrient ingestion by healthy baboons.
Topics: Animals; Antibodies, Monoclonal; Blood Glucose; Fasting; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Glucose; Glucose Tolerance Test; Insulin; Male; Papio; Peptide Fragments; Receptors, Glucagon; Xylose | 1996 |
Gastric emptying and release of incretin hormones after glucose ingestion in humans.
Topics: Adult; Blood Glucose; C-Peptide; Duodenum; Gastric Emptying; Gastric Inhibitory Polypeptide; Gastric Mucosa; Gastrointestinal Hormones; Gastrointestinal Motility; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Humans; Insulin; Insulin Secretion; Male; Peptide Fragments | 1996 |
Comparison of sandwich enzyme-linked immunoadsorbent assay and radioimmunoassay for determination of exogenous glucagon-like peptide-1(7-36)amide in plasma.
Topics: Amino Acid Sequence; Animals; Antibodies; Cats; Chromatography, High Pressure Liquid; Dogs; Enzyme-Linked Immunosorbent Assay; Epitopes; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Molecular Sequence Data; Neurotransmitter Agents; Peptide Fragments; Rabbits; Radioimmunoassay; Rats; Reference Values; Sensitivity and Specificity; Sequence Homology, Amino Acid; Swine; Swine, Miniature | 1995 |
Distribution of GLP-1 binding sites in the rat brain: evidence that exendin-4 is a ligand of brain GLP-1 binding sites.
Topics: Animals; Autoradiography; Binding Sites; Brain; Exenatide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Kinetics; Male; Peptide Fragments; Peptides; Radioligand Assay; Rats; Rats, Wistar; Venoms | 1995 |
GIP and GLP-1(7-36)amide secretion in response to intraduodenal infusions of nutrients in pigs.
Topics: Analysis of Variance; Animals; Blood Glucose; Dietary Fats; Duodenum; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Insulin; Insulin Secretion; Peptide Fragments; Radioimmunoassay; Sodium Chloride; Swine; Triglycerides | 1995 |
Intra-islet regulation of hormone secretion by glucagon-like peptide-1-(7--36) amide.
Topics: Animals; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Glucose; Hormones; Insulin; Insulin Secretion; Islets of Langerhans; Male; Peptide Fragments; Peptides; Rats; Rats, Sprague-Dawley; Receptors, Glucagon; Somatostatin | 1995 |
The third cytoplasmic domain of the GLP-1[7-36 amide] receptor is required for coupling to the adenylyl cyclase system.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Cell Line; Cyclic AMP; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Protein Conformation; Rats; Receptors, Glucagon; Structure-Activity Relationship | 1996 |
Release of glucagon-like peptide 1 (GLP-1 [7-36 amide]), gastric inhibitory polypeptide (GIP) and insulin in response to oral glucose after upper and lower intestinal resections.
Topics: Adult; Aged; C-Peptide; Colectomy; Crohn Disease; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Tolerance Test; Humans; Insulin; Intestine, Large; Intestine, Small; Male; Middle Aged; Peptide Fragments; Postoperative Complications | 1996 |
Glucagon-like peptide-1(7-36)amide induces the release of aspartic acid and glutamine by the ventromedial hypothalamus of the conscious rat.
Topics: Animals; Aspartic Acid; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glutamine; Hypothalamus, Middle; Male; Microdialysis; Neurotransmitter Agents; Peptide Fragments; Rats; Rats, Wistar | 1995 |
Glucagon-like peptide-1(7-36)amide enhances insulin-stimulated glucose uptake and decreases intracellular cAMP content in isolated rat adipocytes.
Topics: 1-Methyl-3-isobutylxanthine; Adipocytes; Animals; Colforsin; Cyclic AMP; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Glucose; Insulin; Male; Peptide Fragments; Peptides; Phosphodiesterase Inhibitors; Rats | 1996 |
The effect of some gastrointestinal peptides on pentagastrin-stimulated acid secretion and oxyntic mucosal histamine in rats.
Topics: Animals; Gastric Acid; Gastric Inhibitory Polypeptide; Gastric Mucosa; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Histamine; Histidine Decarboxylase; Male; Neurotransmitter Agents; Pentagastrin; Peptide Fragments; Rats; Rats, Wistar; Somatostatin; Vasoactive Intestinal Peptide | 1996 |
Glucagon-like peptide-1(7-36)amide increases cyclic AMP accumulation in normal islets.
Topics: Animals; Cyclic AMP; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Islets of Langerhans; Peptide Fragments; Rats; Rats, Sprague-Dawley | 1996 |
Insulinotropic effects of cholecystokinin, gastric inhibitory polypeptide and glucagon-like peptide-1 during perifusion of short-term cultured canine isolated islets.
Topics: Animals; Cells, Cultured; Cholecystokinin; Dogs; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Insulin; Islets of Langerhans; Peptide Fragments; Peptides; Protein Precursors | 1995 |
Induction of intestinal epithelial proliferation by glucagon-like peptide 2.
Topics: Animals; Cell Division; Glicentin; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Glucagonoma; Ileum; Immunohistochemistry; Intestinal Mucosa; Jejunum; Kinetics; Mice; Mice, Nude; Organ Size; Pancreatic Hormones; Pancreatic Neoplasms; Peptide Fragments; Peptides; Proglucagon; Proliferating Cell Nuclear Antigen; Protein Precursors; Rats; Transplantation, Heterologous | 1996 |
Effects of glucagon and glucagon-like peptide-1-(7-36) amide on C cells from rat thyroid and medullary thyroid carcinoma CA-77 cell line.
Topics: Animals; Binding, Competitive; Calcitonin; Carcinoma, Medullary; Cyclic AMP; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Peptide Fragments; Perfusion; Rats; Rats, Wistar; Thyroid Gland; Thyroid Neoplasms; Tumor Cells, Cultured | 1996 |
Effects of glucagon-like peptide-I on glucose turnover in rats.
Topics: Animals; Blood Glucose; Eating; Fasting; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Insulin; Male; Metabolic Clearance Rate; Peptide Fragments; Rats; Rats, Wistar | 1996 |
Glucagon-like-peptide-1 (7-36) amide improves glucose sensitivity in beta-cells of NOD mice.
Topics: Animals; Cells, Cultured; Diabetes Mellitus, Type 2; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Mice; Mice, Inbred NOD; Mice, Mutant Strains; Pancreas; Peptide Fragments; Time Factors | 1996 |
Inositolphosphoglycans are possible mediators of the glucagon-like peptide 1 (7-36)amide action in the liver.
Topics: Animals; Cell Line, Transformed; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glycogen; Glycogen Synthase; Glycosylphosphatidylinositols; Humans; Liver; Neurotransmitter Agents; Peptide Fragments; Rats | 1996 |
The entero-insular axis in polycystic ovarian syndrome.
Topics: Adult; Blood Glucose; C-Peptide; Case-Control Studies; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Tolerance Test; Humans; Hyperinsulinism; Insulin; Neurotransmitter Agents; Peptide Fragments; Polycystic Ovary Syndrome; Proinsulin | 1996 |
Investigation of glucose-dependent insulinotropic polypeptide-(1-42) and glucagon-like peptide-1-(7-36) degradation in vitro by dipeptidyl peptidase IV using matrix-assisted laser desorption/ionization-time of flight mass spectrometry. A novel kinetic app
Topics: Animals; Dipeptidyl Peptidase 4; Enzymes; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Hydrolysis; Kinetics; Peptide Fragments; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine | 1996 |
Secretion of the incretin hormones glucagon-like peptide-1 and gastric inhibitory polypeptide correlates with insulin secretion in normal man throughout the day.
Topics: Adult; Circadian Rhythm; Female; Gastric Inhibitory Polypeptide; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Insulin Secretion; Intestine, Small; Male; Peptide Fragments | 1996 |
Glucagon-like peptide-1(7-36)amide and cytoplasmic calcium in insulin producing cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Cytoplasm; Fura-2; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Insulin; Insulinoma; Islets of Langerhans; Male; Neurotransmitter Agents; Peptide Fragments; Phosphodiesterase Inhibitors; Protein Precursors; Rats; Rats, Sprague-Dawley; Sincalide; Tumor Cells, Cultured | 1996 |
Colocalization of glucagon-like peptide-1 (GLP-1) receptors, glucose transporter GLUT-2, and glucokinase mRNAs in rat hypothalamic cells: evidence for a role of GLP-1 receptor agonists as an inhibitory signal for food and water intake.
Topics: Animals; Cerebral Ventricles; Drinking Behavior; Feeding Behavior; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Glucokinase; Glucose Transporter Type 2; Hypothalamus; In Situ Hybridization; Injections, Intraventricular; Male; Monosaccharide Transport Proteins; Neurotransmitter Agents; Peptide Fragments; Peptides; Rats; Rats, Wistar; Receptors, Glucagon; RNA, Messenger; Signal Transduction; Transcription, Genetic | 1996 |
Normalization of insulin responses to glucose by overnight infusion of glucagon-like peptide 1 (7-36) amide in patients with NIDDM.
Topics: Blood Glucose; Diabetes Mellitus, Type 2; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Homeostasis; Humans; Infusions, Intravenous; Insulin; Insulin Secretion; Islets of Langerhans; Male; Middle Aged; Models, Biological; Neurotransmitter Agents; Peptide Fragments; Reference Values; Time Factors | 1996 |
Glucagon-like peptide-1(7-36) amide and glycogen synthesis in the liver.
Topics: Animals; Cells, Cultured; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Insulin; Kinetics; Liver; Liver Glycogen; Peptide Fragments; Rats | 1996 |
Central administration of GLP-1-(7-36) amide inhibits food and water intake in rats.
Topics: Animals; Behavior, Animal; Brain; Drinking; Eating; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Injections, Intraventricular; Male; Natriuresis; Peptide Fragments; Rats; Rats, Wistar | 1996 |
Central infusions of leptin and GLP-1-(7-36) amide differentially stimulate c-FLI in the rat brain.
Topics: Animals; Brain; Eating; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Immunohistochemistry; Injections, Intraventricular; Leptin; Male; Peptide Fragments; Proteins; Proto-Oncogene Proteins c-fos; Rats; Rats, Inbred Strains; Tissue Distribution | 1996 |
Gut incretin hormones in identical twins discordant for non-insulin-dependent diabetes mellitus (NIDDM)--evidence for decreased glucagon-like peptide 1 secretion during oral glucose ingestion in NIDDM twins.
Topics: Administration, Oral; Area Under Curve; Body Mass Index; Diabetes Mellitus, Type 2; Fasting; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glucose Tolerance Test; Humans; Insulin; Insulin Secretion; Intestinal Mucosa; Male; Middle Aged; Neurotransmitter Agents; Peptide Fragments; Protein Precursors; Sex Characteristics | 1996 |
The enteroinsular axis in dipeptidyl peptidase IV-negative rats.
Topics: Animals; Dipeptidyl Peptidase 4; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glucose Tolerance Test; Insulin; Insulin Secretion; Peptide Fragments; Perfusion; Rats; Rats, Inbred F344 | 1996 |
Effects of somatostatin-28 on circulating concentrations of insulin and gut hormones in sheep.
Topics: Animals; Depression, Chemical; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Insulin; Peptide Fragments; Protein Precursors; Sheep; Somatostatin; Somatostatin-28 | 1996 |
Vagal hepatopancreatic reflex effect evoked by intraportal appearance of tGLP-1.
Topics: Afferent Pathways; Animals; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Injections, Intravenous; Liver; Male; Pancreas; Peptide Fragments; Portal Vein; Protein Precursors; Rats; Rats, Wistar; Reflex; Time Factors; Vagus Nerve | 1996 |
The hepatic vagal nerve is receptive to incretin hormone glucagon-like peptide-1, but not to glucose-dependent insulinotropic polypeptide, in the portal vein.
Topics: Afferent Pathways; Animals; Electrophysiology; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Injections, Intravenous; Liver; Male; Neurotransmitter Agents; Peptide Fragments; Portal Vein; Rats; Rats, Wistar; Vagus Nerve | 1996 |
Interactions of exendin-(9-39) with the effects of glucagon-like peptide-1-(7-36) amide and of exendin-4 on arterial blood pressure and heart rate in rats.
Topics: Animals; Blood Pressure; Exenatide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Heart Rate; Male; Peptide Fragments; Peptides; Rats; Rats, Sprague-Dawley; Venoms | 1996 |
Truncated glucagon-like peptide-1 and oxyntomodulin stimulate somatostatin release from rabbit fundic D-cells in primary culture.
Topics: Animals; Cells, Cultured; Gastric Acid; Gastric Fundus; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Oxyntomodulin; Peptide Fragments; Rabbits; Somatostatin | 1996 |
Attenuated GLP-1 secretion in obesity: cause or consequence?
Topics: Adult; Case-Control Studies; Dietary Carbohydrates; Dietary Fats; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Heparin; Humans; Obesity; Peptide Fragments; Radioimmunoassay | 1996 |
Postprandial glucose-dependent insulinotropic polypeptide and insulin responses in patients with chronic pancreatitis with and without secondary diabetes.
Topics: Adult; Age Factors; Diabetes Mellitus; Digestion; Exocrine Pancreatic Insufficiency; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Male; Middle Aged; Pancreatitis; Peptide Fragments; Postprandial Period; Sex Factors | 1996 |
Glucagon-like peptide-1 and satiety.
Topics: Animals; Avoidance Learning; Eating; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Neuropeptides; Peptide Fragments; Proto-Oncogene Proteins c-fos; Rats; Saccharin; Satiety Response; Taste | 1997 |
Regulation of glycosylphosphatidylinositol-specific phospholipase D secretion from beta TC3 cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Carbachol; Cycloheximide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Immunohistochemistry; Insulin; Insulin Secretion; Insulinoma; Islets of Langerhans; Kinetics; Mice; Pancreatic Neoplasms; Peptide Fragments; Phospholipase D; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1997 |
Glucagon-like peptide-1-(9-36) amide is a major metabolite of glucagon-like peptide-1-(7-36) amide after in vivo administration to dogs, and it acts as an antagonist on the pancreatic receptor.
Topics: Animals; Chromatography, High Pressure Liquid; Cricetinae; Dogs; Enzyme-Linked Immunosorbent Assay; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Humans; Pancreas; Peptide Fragments; Radioimmunoassay; Receptors, Glucagon | 1996 |
Incretin hormone expression in the gut of diabetic mice and rats.
Topics: Animals; Blotting, Northern; Colon; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Disease Models, Animal; Gastric Inhibitory Polypeptide; Gene Expression; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Intestinal Mucosa; Intestine, Small; Intestines; Mice; Mice, Inbred NOD; Peptide Fragments; Proglucagon; Protein Precursors; Rats; Rats, Zucker; Rectum; RNA, Messenger; Tissue Distribution | 1997 |
Protein kinase A-dependent stimulation of exocytosis in mouse pancreatic beta-cells by glucose-dependent insulinotropic polypeptide.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Cell Membrane; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Electric Conductivity; Enzyme Inhibitors; Exocytosis; Gastric Inhibitory Polypeptide; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Islets of Langerhans; Membrane Potentials; Mice; Mice, Inbred Strains; Peptide Fragments; Phosphodiesterase Inhibitors; Tetradecanoylphorbol Acetate; Thionucleotides | 1997 |
Exendin-4 agonist and exendin(9-39)amide antagonist of the GLP-1(7-36)amide effects in liver and muscle.
Topics: Animals; Cyclic AMP; Energy Metabolism; Enzyme Activation; Exenatide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glycogen; Glycogen Synthase; Insulin; Liver; Muscle, Skeletal; Peptide Fragments; Peptides; Phosphorylase a; Rats; Rats, Wistar; Venoms | 1997 |
Cloning and characterization of the 5' flanking sequences (promoter region) of the human GLP-1 receptor gene.
Topics: Base Sequence; Cloning, Molecular; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Humans; Insulinoma; Molecular Sequence Data; Peptide Fragments; Promoter Regions, Genetic; Receptors, Glucagon; Sequence Analysis, DNA; Transcription, Genetic; Tumor Cells, Cultured | 1997 |
Endoproteolysis of glucagon-like peptide (GLP)-1 (7-36) amide by ectopeptidases in RINm5F cells.
Topics: Amino Acid Sequence; Animals; Cell Membrane; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Hydrolysis; Insulinoma; Peptide Fragments; Peptide Hydrolases; Rats; Tumor Cells, Cultured | 1997 |
Multisite regulation of insulin secretion by cAMP-increasing agonists: evidence that glucagon-like peptide 1 and glucagon act via distinct receptors.
Topics: Animals; Calcium; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Electrophysiology; Enzyme Activation; Exocytosis; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Mice; Mice, Inbred Strains; Neurotransmitter Agents; Peptide Fragments; Peptides; Receptors, Cell Surface | 1997 |
Cardiovascular and pancreatic endocrine responses to glucagon-like peptide-1(7-36) amide in the conscious calf.
Topics: Amino Acids; Animals; Blood Glucose; Blood Pressure; Cattle; Enzyme Inhibitors; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Heart Rate; Insulin; Insulin Secretion; Islets of Langerhans; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroprusside; Pancreatic Polypeptide; Peptide Fragments | 1997 |
High potency antagonists of the pancreatic glucagon-like peptide-1 receptor.
Topics: Amino Acid Sequence; Animals; Binding, Competitive; CHO Cells; Cricetinae; Cyclic AMP; Exenatide; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Molecular Sequence Data; Peptide Fragments; Peptides; Rats; Receptors, Glucagon; Recombinant Fusion Proteins; Sequence Deletion; Structure-Activity Relationship; Transfection; Venoms | 1997 |
GLP-1 (7-36) amide activates L-type Ca2+ channels of pancreatic B-cells through c-AMP signaling.
Topics: Action Potentials; Animals; Barium; Calcium Channels; Cyclic AMP; Electric Conductivity; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Islets of Langerhans; Male; Peptide Fragments; Rats; Signal Transduction | 1997 |
Identification of amidated forms of GLP-1 in rat tissues using a highly sensitive radioimmunoassay.
Topics: Animals; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Hypothalamus; Ileum; Immune Sera; Intubation, Gastrointestinal; Male; Organ Specificity; Pancreas; Peptide Fragments; Peptides; Rabbits; Radioimmunoassay; Rats; Rats, Wistar | 1997 |
Novel signal transduction and peptide specificity of glucagon-like peptide receptor in 3T3-L1 adipocytes.
Topics: 3T3 Cells; Adipocytes; Animals; Binding, Competitive; Calcium; CHO Cells; Cricetinae; Cyclic AMP; Exenatide; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Lipolysis; Mice; Peptide Fragments; Peptides; Receptors, Gastrointestinal Hormone; Receptors, Glucagon; Signal Transduction; Venoms | 1997 |
Decreased intake of a liquid diet in nonfood-deprived rats following intra-PVN injections of GLP-1 (7-36) amide.
Topics: Adrenergic alpha-Agonists; Animals; Depression, Chemical; Diet; Eating; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Male; Microinjections; Neurotransmitter Agents; Norepinephrine; Paraventricular Hypothalamic Nucleus; Peptide Fragments; Rats; Rats, Sprague-Dawley | 1997 |
GLP-1 (7-36) amide: effects on glucose transport and metabolism in rat adipose tissue.
Topics: Adipose Tissue; Animals; Biological Transport; Deoxyglucose; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glycogen; Insulin; Lipids; Male; Oxidation-Reduction; Peptide Fragments; Rats; Rats, Wistar | 1997 |
Regulation of growth hormone secretion in lactating sheep.
Topics: Animals; Eating; Fasting; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Growth Hormone; Homeostasis; Lactation; Peptide Fragments; Sheep | 1997 |
Glucagon-like peptide-1(7-36)-amide confers glucose sensitivity to previously glucose-incompetent beta-cells in diabetic rats: in vivo and in vitro studies.
Topics: Animals; Culture Techniques; Cyclic AMP; Diabetes Mellitus, Experimental; DNA; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glucose Tolerance Test; Insulin; Insulin Secretion; Islets of Langerhans; Male; Neurotransmitter Agents; Peptide Fragments; Perfusion; Rats; Rats, Wistar | 1997 |
Glucagon-like peptide 1 (7-36) amide stimulates exocytosis in human pancreatic beta-cells by both proximal and distal regulatory steps in stimulus-secretion coupling.
Topics: Adult; Calcium; Calcium Channels; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Exocytosis; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Islets of Langerhans; Male; Membrane Potentials; Middle Aged; Neurotransmitter Agents; Peptide Fragments; Potassium Channels; Somatostatin | 1998 |
Dual glucagon recognition by pancreatic beta-cells via glucagon and glucagon-like peptide 1 receptors.
Topics: Animals; Cells, Cultured; Cyclic AMP; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Insulin; Iodine Radioisotopes; Islets of Langerhans; Liver; Male; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptors, Glucagon | 1998 |
Glucagon-like peptide-1-(7-36) amide and peptide YY mediate intraduodenal fat-induced inhibition of acid secretion in dogs.
Topics: Animals; Benzodiazepinones; Devazepide; Dogs; Duodenum; Fats; Gastric Acid; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Peptide Fragments; Peptide YY; Protein Precursors | 1998 |
PVN infusion of GLP-1-(7-36) amide suppresses feeding but does not induce aversion or alter locomotion in rats.
Topics: Animals; Avoidance Learning; Cerebral Ventricles; Drinking Behavior; Feeding Behavior; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Infusions, Parenteral; Male; Motor Activity; Paraventricular Hypothalamic Nucleus; Peptide Fragments; Rats; Rats, Sprague-Dawley; Stereotaxic Techniques; Stereotyped Behavior; Time Factors | 1998 |
Dipeptidyl peptidase IV resistant analogues of glucagon-like peptide-1 which have extended metabolic stability and improved biological activity.
Topics: Animals; Cross Reactions; Dipeptidyl Peptidase 4; Drug Stability; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; In Vitro Techniques; Insulin; Insulin Secretion; Pancreas; Peptide Fragments; Perfusion; Protein Binding; Protein Precursors; Receptors, Glucagon; Swine | 1998 |
Cyclic AMP, a mediator of GLP-1, acts in concert with glucose and tolbutamide to increase cytosolic Ca2+ in pancreatic B-cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Cytosol; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Islets of Langerhans; Peptide Fragments; Potassium Chloride; Rats; Rats, Wistar; Tolbutamide | 1997 |
Effect of chronic central administration of glucagon-like peptide-1 (7-36) amide on food consumption and body weight in normal and obese rats.
Topics: Animals; Body Weight; Eating; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Injections, Intraventricular; Insulinoma; Male; Neurotransmitter Agents; Obesity; Pancreatic Neoplasms; Peptide Fragments; Rats; Rats, Sprague-Dawley; Rats, Zucker; Receptors, Glucagon; Tumor Cells, Cultured | 1998 |
Glucagon-like peptide-1-(7-36)amide increases pulmonary surfactant secretion through a cyclic adenosine 3',5'-monophosphate-dependent protein kinase mechanism in rat type II pneumocytes.
Topics: Adrenergic beta-Agonists; Animals; Calcimycin; Calcium-Transporting ATPases; Cells, Cultured; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Kinetics; Lung; Male; Peptide Fragments; Phosphatidylcholines; Pulmonary Surfactants; Rats; Rats, Wistar; Terbutaline; Tetradecanoylphorbol Acetate; Thapsigargin | 1998 |
Glucagon-like peptide 1(7-36) amide's central inhibition of feeding and peripheral inhibition of drinking are abolished by neonatal monosodium glutamate treatment.
Topics: Angiotensin II; Animals; Animals, Newborn; Arcuate Nucleus of Hypothalamus; Avoidance Learning; Blood Glucose; Blood-Brain Barrier; Brain; Cerebral Ventricles; Drinking; Eating; Food Additives; Food Deprivation; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Male; Neuropeptide Y; Peptide Fragments; Rats; Rats, Wistar; Sodium Glutamate; Subfornical Organ; Taste | 1998 |
Effects of glucagon-like peptide 1 (7-36 amide) on glucose kinetics during somatostatin-induced suppression of insulin secretion in healthy men.
Topics: Adult; Blood Glucose; C-Peptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Clamp Technique; Humans; Hyperglycemia; Infusions, Intravenous; Insulin; Insulin Secretion; Kinetics; Male; Peptide Fragments; Proinsulin; Somatostatin | 1998 |
Inositolphosphoglycans possibly mediate the effects of glucagon-like peptide-1(7-36)amide on rat liver and adipose tissue.
Topics: Adipocytes; Adipose Tissue; Animals; Cells, Cultured; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glycosylphosphatidylinositols; Liver; Male; Peptide Fragments; Rats; Rats, Wistar | 1998 |
Plasma glucagon-like peptide-1 (7-36) amide (GLP-1) response to liquid phase, solid phase, and meals of differing lipid composition.
Topics: Adult; Beverages; Blood Glucose; Dietary Fats; Dietary Fats, Unsaturated; Energy Intake; Female; Food; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Kinetics; Male; Peptide Fragments | 1998 |
The inhibitory effect of glucagon-like peptide-1 (7-36)amide on antral motility is antagonized by its N-terminally truncated primary metabolite GLP-1 (9-36)amide.
Topics: Animals; Dose-Response Relationship, Drug; Gastrointestinal Hormones; Gastrointestinal Motility; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Hypoglycemia; Peptide Fragments; Peptides; Pyloric Antrum; Swine | 1998 |
Central infusion of glucagon-like peptide-1-(7-36) amide (GLP-1) receptor antagonist attenuates lithium chloride-induced c-Fos induction in rat brainstem.
Topics: Animals; Brain Stem; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Guinea Pigs; Infusions, Parenteral; Injections, Intraperitoneal; Injections, Intraventricular; Insulin; Insulin Secretion; Insulinoma; Lithium Chloride; Male; Neurons; Peptide Fragments; Proto-Oncogene Proteins c-fos; Rats; Rats, Long-Evans; Receptors, Glucagon; Signal Transduction; Tumor Cells, Cultured | 1998 |
Effects of glucagon-like peptide-1 (7-36)amide on insulin stimulated rat skeletal muscle glucose transport.
Topics: Animals; Biological Transport; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Hypoglycemic Agents; In Vitro Techniques; Insulin; Male; Muscle, Skeletal; Peptide Fragments; Rats; Rats, Wistar | 1998 |
Functional interactions between melanin-concentrating hormone, neuropeptide Y, and anorectic neuropeptides in the rat hypothalamus.
Topics: alpha-MSH; Animals; Appetite Depressants; Appetite Stimulants; Drug Interactions; Eating; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Hypothalamic Hormones; Hypothalamus; Injections, Intraventricular; Kinetics; Male; Melanins; Neuropeptide Y; Neurotensin; Peptide Fragments; Pituitary Hormones; Rats; Rats, Sprague-Dawley | 1998 |
Glycation of glucagon-like peptide-1(7-36)amide: characterization and impaired action on rat insulin secreting cells.
Topics: Amino Acid Sequence; Animals; Antibody Specificity; Cell Line; Chromatography, High Pressure Liquid; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glycosylation; Insulin; Insulin Secretion; Intestine, Small; Islets of Langerhans; Mice; Molecular Sequence Data; Peptide Fragments; Radioimmunoassay; Rats; Sequence Analysis; Structure-Activity Relationship | 1998 |
A synthetic glucagon-like peptide-1 analog with improved plasma stability.
Topics: Animals; Chromatography, High Pressure Liquid; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Glucose; Humans; Insulin; Insulin Secretion; Male; Peptide Fragments; Protein Precursors; Rats; Rats, Wistar; Receptors, Glucagon; Time Factors; Tumor Cells, Cultured | 1998 |
Amidated and non-amidated glucagon-like peptide-1 (GLP-1): non-pancreatic effects (cephalic phase acid secretion) and stability in plasma in humans.
Topics: Adult; Bacitracin; Female; Gastric Acid; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Male; Middle Aged; Oligopeptides; Peptide Fragments; Protein Precursors; Stomach | 1998 |
Glucagon-like peptide-1 inhibits gastropancreatic function by inhibiting central parasympathetic outflow.
Topics: Animals; Bicarbonates; Blood Glucose; Gastric Acid; Gastrins; Gastrointestinal Motility; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Islets of Langerhans; Muscle Contraction; Muscle, Smooth; Neurotransmitter Agents; Pancreas; Pancreatic Juice; Pancreatic Polypeptide; Parasympathetic Nervous System; Peptide Fragments; Protein Precursors; Stomach; Swine; Vagotomy; Vagus Nerve | 1998 |
The ageing entero-insular axis.
Topics: Acetaminophen; Adult; Aged; Aging; Blood Glucose; Body Mass Index; Body Weight; Diabetes Mellitus, Type 2; Dietary Carbohydrates; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Intolerance; Humans; Insulin; Insulin Secretion; Peptide Fragments; Postmenopause; Premenopause; Risk Factors | 1998 |
Repeated intracerebroventricular administration of glucagon-like peptide-1-(7-36) amide or exendin-(9-39) alters body weight in the rat.
Topics: Animals; Body Weight; Energy Intake; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Injections, Intraventricular; Male; Neurotransmitter Agents; Peptide Fragments; Rats; Rats, Wistar | 1999 |
The relative contribution of insulin secretory capacity, insulin action, and incretins to metabolic control after islet transplantation in dogs.
Topics: Animals; Dogs; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glucose Tolerance Test; Insulin; Insulin Secretion; Islets of Langerhans; Islets of Langerhans Transplantation; Peptide Fragments | 1999 |
Inhibition of carbohydrate-mediated glucagon-like peptide-1 (7-36)amide secretion by circulating non-esterified fatty acids.
Topics: Adult; Analysis of Variance; Area Under Curve; Case-Control Studies; Dietary Carbohydrates; Fatty Acids, Nonesterified; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Tolerance Test; Heparin; Humans; Insulin; Models, Biological; Neurotransmitter Agents; Obesity; Peptide Fragments; Postprandial Period; Pyrazines; Triglycerides | 1999 |
Glucose-dependent stimulatory effect of glucagon-like peptide 1(7-36) amide on the electrical activity of pancreatic beta-cells recorded in vivo.
Topics: Animals; Blood Glucose; Electrophysiology; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Hypoglycemic Agents; Insulin; Insulin Secretion; Islets of Langerhans; Mice; Osmolar Concentration; Peptide Fragments; Tolbutamide | 1999 |
Insulin secretion and intestinal peptides during lactation in sheep.
Topics: Animals; Blood Glucose; Female; Gastric Inhibitory Polypeptide; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Insulin; Insulin Secretion; Lactation; Peptide Fragments; Sheep; Somatostatin; Somatostatin-28 | 1999 |
The influence of the colon on postprandial glucagon-like peptide 1 (7-36) amide concentration in man.
Topics: Analysis of Variance; Blood Glucose; Case-Control Studies; Colitis, Ulcerative; Colon; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Ileostomy; Insulin; Male; Middle Aged; Neurotransmitter Agents; Peptide Fragments; Postprandial Period | 1999 |
Effect of large bowel fermentation on insulin, glucose, free fatty acids, and glucagon-like peptide 1 (7-36) amide in patients with coronary heart disease.
Topics: Aged; Blood Glucose; Coronary Disease; Fatty Acids, Nonesterified; Fermentation; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Intestinal Absorption; Intestine, Large; Lactulose; Male; Middle Aged; Peptide Fragments; Risk Factors | 1999 |
Effect of GIP and GLP-1 antagonists on insulin release in the rat.
Topics: Absorption; Animals; Blood Glucose; Dose-Response Relationship, Drug; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Insulin; Peptide Fragments; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptors, Gastrointestinal Hormone | 1999 |
In vivo dynamic distribution of 131I-glucagon-like peptide-1 (7-36) amide in the rat studied by gamma camera.
Topics: Animals; Brain; Gamma Cameras; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Iodine Radioisotopes; Male; Metabolic Clearance Rate; Peptide Fragments; Rats; Rats, Sprague-Dawley; Tissue Distribution | 1999 |
Biochemical basis of oligofructose-induced hypolipidemia in animal models.
Topics: Animals; Blood Glucose; Dietary Fiber; Fatty Acids; Gene Expression Regulation, Enzymologic; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Insulin; Lipoproteins; Liver; Male; Neurotransmitter Agents; Oligosaccharides; Peptide Fragments; Rats; Rats, Wistar; Triglycerides | 1999 |
[Inhibition of incretin degradation--a new therapy principle for treatment of type 2 diabetes?].
Topics: Administration, Oral; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Enzyme Inhibitors; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Hypoglycemic Agents; Isoleucine; Peptide Fragments; Rats; Rats, Zucker; Thiazoles | 1999 |
Glucagon-like peptide-1 modulates neuronal activity in the rat's hippocampus.
Topics: Animals; Aspartic Acid; Cerebral Cortex; Electroencephalography; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Glutamic Acid; Glutamine; Hippocampus; Injections, Intraventricular; Male; Neurons; Peptide Fragments; Peptides; Protein Precursors; Rats; Rats, Wistar; Receptors, Glucagon; Stimulation, Chemical; Ventromedial Hypothalamic Nucleus | 1999 |
Glucagon-like peptide-1-(7-36)amide is transformed to glucagon-like peptide-1-(9-36)amide by dipeptidyl peptidase IV in the capillaries supplying the L cells of the porcine intestine.
Topics: Animals; Capillaries; Chromatography, High Pressure Liquid; Dipeptidyl Peptidase 4; Endothelium, Vascular; Epithelium; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Histocytochemistry; Immunohistochemistry; Intestinal Mucosa; Microvilli; Peptide Fragments; Peptides; Swine | 1999 |
Twenty-four-hour insulin secretion rates, circulating concentrations of fuel substrates and gut incretin hormones in healthy offspring of Type II (non-insulin-dependent) diabetic parents: evidence of several aberrations.
Topics: Adult; Blood; Blood Glucose; C-Peptide; Circadian Rhythm; Diabetes Mellitus, Type 2; Eating; Energy Metabolism; Fatty Acids, Nonesterified; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Tolerance Test; Humans; Insulin; Insulin Secretion; Intestinal Mucosa; Male; Middle Aged; Peptide Fragments; Proinsulin; Reference Values | 1999 |
Inhibition of dipeptidyl peptidase IV with NVP-DPP728 increases plasma GLP-1 (7-36 amide) concentrations and improves oral glucose tolerance in obese Zucker rats.
Topics: Animals; Dipeptidyl Peptidase 4; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glucose Tolerance Test; Male; Nitriles; Obesity; Osmolar Concentration; Peptide Fragments; Pyrrolidines; Rats; Rats, Zucker; Reference Values | 1999 |
A functional role for central glucagon-like peptide-1 receptors in lithium chloride-induced anorexia.
Topics: Animals; Anorexia; Brain; Dose-Response Relationship, Drug; Eating; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Injections, Intraventricular; Lithium Chloride; Male; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptors, Glucagon | 1999 |
Neural contribution to the effect of glucagon-like peptide-1-(7-36) amide on arterial blood pressure in rats.
Topics: Animals; Blood Pressure; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Heart Rate; Humans; Injections, Intravenous; Injections, Intraventricular; Male; Neurotransmitter Agents; Peptide Fragments; Peptides; Rats; Rats, Sprague-Dawley; Vagotomy; Vagus Nerve | 1999 |
Glucose intolerance caused by a defect in the entero-insular axis: a study in gastric inhibitory polypeptide receptor knockout mice.
Topics: Administration, Oral; Animals; Diabetes Mellitus, Type 2; Dietary Fats; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glucose Intolerance; Glucose Tolerance Test; Homeostasis; Injections, Intraperitoneal; Insulin; Insulin Resistance; Insulin Secretion; Intestines; Islets of Langerhans; Mice; Mice, Knockout; Models, Biological; Peptide Fragments; Protein Precursors; Receptors, Gastrointestinal Hormone | 1999 |
Effects of substitution of N-terminal amino acid of glucagon-like peptide-1 (7-36) amide on food intake of the neonatal chick.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Animals, Newborn; Chickens; Eating; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Histidine; Injections, Intraventricular; Male; Molecular Sequence Data; Peptide Fragments; Protein Precursors; Structure-Activity Relationship; Tyrosine | 1999 |
Increased glucagon-like peptide-1 receptor expression in glia after mechanical lesion of the rat brain.
Topics: Animals; Brain Injuries; Gene Expression; Glial Fibrillary Acidic Protein; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; In Situ Hybridization; Male; Neuroglia; Peptide Fragments; Rats; Rats, Wistar; Receptors, Glucagon; RNA, Messenger; Wounds, Stab | 1999 |
The role of CNS glucagon-like peptide-1 (7-36) amide receptors in mediating the visceral illness effects of lithium chloride.
Topics: Angiotensins; Animals; Avoidance Learning; Cerebral Ventricles; Drinking Behavior; Energy Intake; Feeding Behavior; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Injections, Intraventricular; Kaolin; Lithium Chloride; Male; Peptide Fragments; Rats; Rats, Long-Evans; Receptors, Glucagon; Sodium, Dietary; Taste; Time Factors | 2000 |
N-terminally modified glucagon-like peptide-1(7-36) amide exhibits resistance to enzymatic degradation while maintaining its antihyperglycaemic activity in vivo.
Topics: Animals; Blood Glucose; Chromatography, High Pressure Liquid; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Homeostasis; Humans; Hypoglycemic Agents; Insulin; Male; Peptide Fragments; Peptides; Rats; Rats, Wistar; Sorbitol | 2000 |
The hepatic vagal reception of intraportal GLP-1 is via receptor different from the pancreatic GLP-1 receptor.
Topics: Animals; Electrophysiology; Exenatide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Injections, Intravenous; Liver; Male; Neurons, Afferent; Pancreas; Peptide Fragments; Peptides; Portal Vein; Rats; Rats, Wistar; Receptors, Glucagon; Vagus Nerve; Venoms | 2000 |
Peripheral versus central effects of glucagon-like peptide-1 receptor agonists on satiety and body weight loss in Zucker obese rats.
Topics: Amines; Animals; Appetite; Body Weight; Brain; Diabetes Mellitus; Drinking; Eating; Exenatide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; In Situ Hybridization; Injections, Intraventricular; Injections, Subcutaneous; Male; Obesity; Peptide Fragments; Peptides; Rats; Rats, Wistar; Rats, Zucker; Receptors, Glucagon; RNA, Messenger; Venoms | 2000 |
Glucagon-like peptide-1 improves insulin and proinsulin binding on RINm5F cells and human monocytes.
Topics: Adult; Animals; Exenatide; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Humans; Insulin; Insulinoma; Male; Monocytes; Pancreatic Neoplasms; Peptide Fragments; Peptides; Proinsulin; Protein Precursors; Rats; Receptors, Glucagon; Tumor Cells, Cultured; Venoms | 2000 |
Characterisation of beta-cell dysfunction of impaired glucose tolerance: evidence for impairment of incretin-induced insulin secretion.
Topics: Adult; Arginine; Blood Glucose; C-Peptide; Fasting; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Clamp Technique; Glucose Intolerance; Glycated Hemoglobin; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Peptide Fragments; Reference Values | 2000 |
Effects of centrally or systemically injected glucagon-like peptide-1 (7-36) amide on release of neurohypophysial hormones and blood pressure in the rat.
Topics: Animals; Blood Pressure; Dose-Response Relationship, Drug; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Hypertension; Injections, Intravenous; Male; Neurotransmitter Agents; Oxytocin; Peptide Fragments; Radioimmunoassay; Rats; Rats, Wistar; Sex Factors; Time Factors; Vasopressins | 2000 |
Portal GLP-1 administration in rats augments the insulin response to glucose via neuronal mechanisms.
Topics: Animals; Atropine Derivatives; Blood Glucose; Chlorisondamine; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Injections, Intravenous; Insulin; Insulin Secretion; Jugular Veins; Kinetics; Male; Parasympatholytics; Peptide Fragments; Portal Vein; Rats; Rats, Sprague-Dawley; Time Factors | 2000 |
Effects of glucagon-like peptide-1 (GLP-1) on glucose homeostasis and food intake.
Topics: Animals; Dipeptidyl Peptidase 4; Eating; Feeding Behavior; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Homeostasis; Insulin; Intestinal Mucosa; Neurotransmitter Agents; Nitriles; Peptide Fragments; Protease Inhibitors; Pyrrolidines; Rats | 2000 |
Degradation and glycemic effects of His(7)-glucitol glucagon-like peptide-1(7-36)amide in obese diabetic ob/ob mice.
Topics: Animals; Blood Glucose; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Eating; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Mice; Mice, Obese; Oligopeptides; Peptide Fragments; Protease Inhibitors; Protein Precursors; Spectrometry, Mass, Electrospray Ionization; Time Factors | 2001 |
Lack of effect of incretin hormones on insulin release from pancreatic islets in the bile duct-ligated rats.
Topics: Animals; Bile Ducts; Bilirubin; Bucladesine; Cholestasis, Extrahepatic; Colforsin; Cyclic AMP; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glucose Tolerance Test; Heterotrimeric GTP-Binding Proteins; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Ligation; Male; Peptide Fragments; Rats; Rats, Wistar | 2001 |
A new hypoglycemic agent, JTT-608, evokes protein kinase A-mediated Ca(2+) signaling in rat islet beta-cells: strict regulation by glucose, link to insulin release, and cooperation with glucagon-like peptide-1(7-36)amide and pituitary adenylate cyclase-ac
Topics: Acetylcholine; Animals; Butyrates; Calcium Channel Blockers; Calcium Signaling; Cell Separation; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Cyclohexanes; Enzyme Activation; Enzyme Inhibitors; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Hypoglycemic Agents; Insulin; Islets of Langerhans; Neuropeptides; Peptide Fragments; Pituitary Adenylate Cyclase-Activating Polypeptide; Rats; Rats, Wistar | 2001 |
Differential effects of glucagon-like peptide-1 (7-36)amide versus cholecystokinin on arginine-induced islet hormone release in vivo and in vitro.
Topics: Animals; Arginine; Cholecystokinin; Drug Combinations; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Insulin; Insulin Secretion; Male; Mice; Pancreas; Peptide Fragments; Perfusion; Rats; Somatostatin | 2001 |
Glucagon-like peptide 1 stimulates lipolysis in clonal pancreatic beta-cells (HIT).
Topics: Calcium; Cell Line; Enzyme Inhibitors; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Hydrogen-Ion Concentration; Intracellular Membranes; Islets of Langerhans; Lactones; Lipase; Lipolysis; Orlistat; Peptide Fragments; Protein Precursors; Sterol Esterase | 2001 |
Synergistic interaction between VIP-related peptides and bombesin on ion transport in guinea pig distal colonic mucosa.
Topics: Animals; Bombesin; Colon; Dose-Response Relationship, Drug; Drug Synergism; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Guinea Pigs; In Vitro Techniques; Intestinal Mucosa; Ion Transport; Male; Neuropeptides; Peptide Fragments; Peptides; Pituitary Adenylate Cyclase-Activating Polypeptide; Vasoactive Intestinal Peptide | 2000 |
Cytosolic calcium handling in islets of normal Wistar and diabetic Goto Kakizaki rats in the presence of glucose and truncated glucagon-like peptide 1 (7-36) amide.
Topics: Animals; Calcium; Cytosol; Diabetes Mellitus, Type 2; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Peptide Fragments; Rats; Rats, Wistar | 2000 |
Effect of glucagon-like peptide-1(7-36)-amide on initial splanchnic glucose uptake and insulin action in humans with type 1 diabetes.
Topics: Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Duodenum; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Human Growth Hormone; Hydrocortisone; Hypoglycemic Agents; Insulin; Intubation; Osmolar Concentration; Peptide Fragments; Viscera | 2001 |
Glucagon-like peptide-1(7-36) amide stimulates surfactant secretion in human type II pneumocytes.
Topics: Adult; Cells, Cultured; Dose-Response Relationship, Drug; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Lung; Male; Middle Aged; Peptide Fragments; Phosphatidylcholines; Pulmonary Surfactants; Reference Values; Sensitivity and Specificity | 2001 |
Glucose competence of the hepatoportal vein sensor requires the presence of an activated glucagon-like peptide-1 receptor.
Topics: Animals; Blood Glucose; Catheters, Indwelling; Enzyme-Linked Immunosorbent Assay; Fasting; Femoral Vein; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Hepatic Veins; Homeostasis; Infusions, Intravenous; Metabolic Clearance Rate; Mice; Mice, Inbred C57BL; Peptide Fragments; Portal System; Portal Vein; Protein Precursors; Tritium; Venoms | 2001 |
The role of postprandial releases of insulin and incretin hormones in meal-induced satiety--effect of obesity and weight reduction.
Topics: Absorptiometry, Photon; Adult; Appetite; Area Under Curve; Energy Intake; Gastric Emptying; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Insulin Resistance; Insulin Secretion; Male; Middle Aged; Obesity; Peptide Fragments; Postprandial Period; Satiation; Weight Loss | 2001 |
Reduction of incretin-like salivatin in saliva from patients with type 2 diabetes and in parotid glands of streptozotocin-diabetic BALB/c mice.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Eating; Enzyme-Linked Immunosorbent Assay; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Hypoglycemic Agents; Male; Mice; Mice, Inbred BALB C; Microscopy, Immunoelectron; Parotid Gland; Peptide Fragments; Peptides; Postprandial Period; Proline-Rich Protein Domains; Saliva; Salivary Proline-Rich Proteins | 2001 |
Urinary excretion of glucagon-like peptide 1 (GLP-1) 7-36 amide in human type 2 (non-insulin-dependent) diabetes mellitus.
Topics: Aged; Albuminuria; Body Mass Index; C-Peptide; Creatinine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glycated Hemoglobin; Humans; Male; Metabolic Clearance Rate; Middle Aged; Peptide Fragments | 2001 |
Critical role of cAMP-GEFII--Rim2 complex in incretin-potentiated insulin secretion.
Topics: Animals; Base Sequence; Carrier Proteins; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DNA Primers; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; GTP-Binding Proteins; Guanine Nucleotide Exchange Factors; Imines; Insulin; Insulin Secretion; Islets of Langerhans; Mice; Nerve Tissue Proteins; Nuclear Proteins; Peptide Fragments; Protein Precursors | 2001 |
Vasorelaxant effect of glucagon-like peptide-(7-36)amide and amylin on the pulmonary circulation of the rat.
Topics: Acetylcholine; Amyloid; Animals; Anti-Ulcer Agents; Calcitonin Gene-Related Peptide; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; In Vitro Techniques; Islet Amyloid Polypeptide; Male; Neurotransmitter Agents; NG-Nitroarginine Methyl Ester; Norepinephrine; Peptide Fragments; Perfusion; Pulmonary Artery; Pulmonary Circulation; Pulmonary Ventilation; Rats; Rats, Sprague-Dawley; Trachea; Vasoactive Intestinal Peptide; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2001 |
Renal effects of glucagon-like peptide in rats.
Topics: Animals; Dose-Response Relationship, Drug; Glomerular Filtration Rate; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Kidney; Male; Neurotransmitter Agents; Peptide Fragments; Rats; Rats, Sprague-Dawley | 2002 |
Effects of glucagon-like peptide-1(7-36) amide on neurohypophysial and cardiovascular functions under hypo- or normotensive hypovolaemia in the rat.
Topics: Analysis of Variance; Animals; Arginine Vasopressin; Blood Pressure; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Hypovolemia; Male; Oxytocin; Peptide Fragments; Pituitary Gland, Posterior; Rats; Rats, Wistar | 2002 |
Anxiogenic-like action of centrally administered glucagon-like peptide-1 in a punished drinking test.
Topics: Amygdala; Animals; Anxiety; Cerebral Ventricles; Conflict, Psychological; Drinking Behavior; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Infusions, Parenteral; Male; Maze Learning; Motor Activity; Peptide Fragments; Protein Precursors; Punishment; Rats; Rats, Sprague-Dawley | 2002 |
GLP-1-(9-36) amide reduces blood glucose in anesthetized pigs by a mechanism that does not involve insulin secretion.
Topics: Anesthesia; Animals; Blood Glucose; Chloralose; Dipeptidyl Peptidase 4; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Infusions, Intravenous; Insulin; Insulin Secretion; Kinetics; Metabolic Clearance Rate; Peptide Fragments; Peptides; Protease Inhibitors; Protein Precursors; Pyrroles; Swine; Valine | 2002 |
Abnormal release of incretins and cortisol after oral glucose in subjects with insulin-resistant myotonic dystrophy.
Topics: Adult; Body Composition; DNA; Dose-Response Relationship, Drug; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Humans; Hydrocortisone; Insulin Resistance; Male; Middle Aged; Myotonic Dystrophy; Peptide Fragments; Regression Analysis; Repetitive Sequences, Nucleic Acid | 2002 |
Hypocretin is an early member of the incretin gene family.
Topics: Animals; Anura; Carrier Proteins; Evolution, Molecular; Exons; Gene Expression Regulation; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Hypothalamus; Intracellular Signaling Peptides and Proteins; Neuropeptides; Orexins; Peptide Fragments; Phylogeny; Protein Structure, Secondary; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid; Sleep; Tetraodontiformes; Urochordata | 2002 |
Identification and functional characterization of melatonin Mel 1a receptors in pancreatic beta cells: potential role in incretin-mediated cell function by sensitization of cAMP signaling.
Topics: Animals; Cell Line; Circadian Rhythm; Cyclic AMP; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Islets of Langerhans; Melatonin; Peptide Fragments; Protein Precursors; Rats; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Second Messenger Systems | 2002 |
GLP-1 receptor signaling contributes to anorexigenic effect of centrally administered oxytocin in rats.
Topics: Animals; Anorexia; Eating; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Injections, Intraventricular; Male; Neurons; Neurotransmitter Agents; Oxytocin; Peptide Fragments; Protein Precursors; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Glucagon; Receptors, Oxytocin; Signal Transduction | 2002 |
Somatostatin-28 regulates GLP-1 secretion via somatostatin receptor subtype 5 in rat intestinal cultures.
Topics: Animals; Cells, Cultured; Fetus; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Intestinal Mucosa; Intestines; Peptide Fragments; Protein Precursors; Rats; Receptors, Somatostatin; Somatostatin; Somatostatin-28 | 2002 |
Glycemic, hormone, and appetite responses to monosaccharide ingestion in patients with type 2 diabetes.
Topics: Adult; Aged; Appetite; Blood Glucose; Diabetes Mellitus, Type 2; Female; Fructose; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Humans; Insulin; Male; Middle Aged; Peptide Fragments | 2002 |
Elevated glucagon-like peptide-1-(7-36)-amide, but not glucose, associated with hyperinsulinemic compensation for fat feeding.
Topics: Animals; Blood Glucose; Blotting, Northern; Dietary Fats; Dogs; Fasting; Fatty Acids, Nonesterified; Gene Expression; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Glucose; Glucose Tolerance Test; Hyperinsulinism; Insulin; Insulin Resistance; Islets of Langerhans; Kinetics; Magnetic Resonance Imaging; Male; Obesity; Peptide Fragments; Receptors, Glucagon; Reverse Transcriptase Polymerase Chain Reaction | 2002 |
The diverse roles of specific GLP-1 receptors in the control of food intake and the response to visceral illness.
Topics: Amygdala; Animals; Anorexia; Appetite Regulation; Behavior, Animal; Catheterization; Conditioning, Psychological; Dose-Response Relationship, Drug; Eating; Fourth Ventricle; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Injections, Intraperitoneal; Injections, Intraventricular; Lateral Ventricles; Lithium Chloride; Male; Paraventricular Hypothalamic Nucleus; Peptide Fragments; Rats; Rats, Long-Evans; Receptors, Glucagon; Signal Transduction; Taste; Visceral Afferents | 2002 |
cAMP-activated protein kinase-independent potentiation of insulin secretion by cAMP is impaired in SUR1 null islets.
Topics: Animals; ATP-Binding Cassette Transporters; Carbazoles; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Indoles; Insulin; Insulin Secretion; Islets of Langerhans; Isoquinolines; Mice; Mice, Knockout; Peptide Fragments; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Kinase C; Pyrroles; Receptors, Drug; Reference Values; Sulfonamides; Sulfonylurea Receptors | 2002 |
The vagus is inhibitory of the late postprandial insulin secretion in conscious pigs.
Topics: Analysis of Variance; Animals; Area Under Curve; Blood Glucose; Consciousness; Female; Food; Gastric Emptying; Gastric Inhibitory Polypeptide; Gastric Mucosa; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Insulin; Insulin Secretion; Peptide Fragments; Postprandial Period; Protein Precursors; Radioimmunoassay; Stomach; Swine; Time Factors; Vagotomy; Vagus Nerve | 2002 |
Comparisons of leptin, incretins and body composition in obese and lean patients with hypopituitarism and healthy individuals.
Topics: Adult; Anthropometry; Body Composition; Case-Control Studies; Cross-Sectional Studies; Fasting; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Human Growth Hormone; Humans; Hypopituitarism; Leptin; Lipids; Male; Middle Aged; Obesity; Peptide Fragments; Peptides; Thinness | 2003 |
Dipeptidyl peptidase IV inhibitor treatment stimulates beta-cell survival and islet neogenesis in streptozotocin-induced diabetic rats.
Topics: Animals; Blood Glucose; Cell Count; Cell Differentiation; Cell Division; Cell Survival; Diabetes Mellitus, Experimental; Dipeptidyl Peptidase 4; Eating; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Tolerance Test; Immunohistochemistry; Insulin; Insulin Secretion; Islets of Langerhans; Lipids; Liver; Male; Peptide Fragments; Phosphoenolpyruvate Carboxykinase (GTP); Protease Inhibitors; Protein Precursors; Rats; Rats, Wistar; Weight Gain | 2003 |
Mechanisms involved in glucagon-like peptide-1 (7-36) amide action on the rat hypothalamo-neurohypophysial system.
Topics: Analysis of Variance; Angiotensin II; Animals; Calcium; Colforsin; Cyclic AMP; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Hypothalamo-Hypophyseal System; Male; Neurotransmitter Agents; Organ Culture Techniques; Oxytocin; Peptide Fragments; Rats; Rats, Wistar; Second Messenger Systems; Vasopressins; Water-Electrolyte Balance | 2003 |
Effects of the novel (Pro3)GIP antagonist and exendin(9-39)amide on GIP- and GLP-1-induced cyclic AMP generation, insulin secretion and postprandial insulin release in obese diabetic (ob/ob) mice: evidence that GIP is the major physiological incretin.
Topics: Animals; Cells, Cultured; Cricetinae; Cricetulus; Cyclic AMP; Diabetes Mellitus; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Hyperinsulinism; Insulin; Insulin Secretion; Mice; Obesity; Peptide Fragments; Postprandial Period; Protein Precursors; Spectrometry, Mass, Electrospray Ionization | 2003 |
Differential activation mechanisms of Erk-1/2 and p70(S6K) by glucose in pancreatic beta-cells.
Topics: Animals; Calcium; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glyburide; Humans; Islets of Langerhans; Isoquinolines; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Peptide Fragments; Phosphorylation; Proto-Oncogene Proteins c-raf; Rats; Rats, Sprague-Dawley; Ribosomal Protein S6 Kinases, 70-kDa; Sulfonamides; Verapamil | 2003 |
Effects of GLP-1-(7-36)NH2, GLP-1-(7-37), and GLP-1- (9-36)NH2 on intravenous glucose tolerance and glucose-induced insulin secretion in healthy humans.
Topics: Adult; Blood Glucose; Fasting; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Tolerance Test; Humans; Insulin; Insulin Secretion; Kinetics; Male; Middle Aged; Peptide Fragments; Peptides; Protein Precursors | 2003 |
Incretin secretion in relation to meal size and body weight in healthy subjects and people with type 1 and type 2 diabetes mellitus.
Topics: Adult; Aged; Blood Glucose; Body Weight; C-Peptide; Case-Control Studies; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Feeding Behavior; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Male; Middle Aged; Obesity; Peptide Fragments; Protein Precursors; Random Allocation | 2003 |
Glucagon-like peptide-1 (7-36) amide prevents the accumulation of pyruvate and lactate in the ischemic and non-ischemic porcine myocardium.
Topics: Animals; Area Under Curve; Blood Glucose; Cardiovascular System; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Ischemia; Lactic Acid; Microdialysis; Myocardial Infarction; Myocardium; Peptide Fragments; Protein Precursors; Pyruvic Acid; Reperfusion Injury; Swine; Time Factors | 2003 |
Glucose-dependent insulinotropic peptide stimulates proliferation and TGF-beta release from MG-63 cells.
Topics: Alkaline Phosphatase; Blotting, Northern; Cell Differentiation; Cell Division; Cell Line, Tumor; Collagen; Dose-Response Relationship, Drug; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Humans; Insulin; Osteoblasts; Peptide Fragments; Peptides; RNA; Thymidine; Transforming Growth Factor beta | 2003 |
CNS glucagon-like peptide-1 receptors mediate endocrine and anxiety responses to interoceptive and psychogenic stressors.
Topics: Adrenocorticotropic Hormone; Amygdala; Animals; Anxiety; Brain; Catheterization; Central Nervous System; Corticosterone; Corticotropin-Releasing Hormone; Dose-Response Relationship, Drug; Drug Administration Routes; Endocrine System; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Hypothalamo-Hypophyseal System; Male; Neuroprotective Agents; Paraventricular Hypothalamic Nucleus; Peptide Fragments; Pituitary-Adrenal System; Rats; Rats, Long-Evans; Receptors, Corticotropin-Releasing Hormone; Receptors, Glucagon; Stress, Psychological | 2003 |
Novel dipeptidyl peptidase IV resistant analogues of glucagon-like peptide-1(7-36)amide have preserved biological activities in vitro conferring improved glucose-lowering action in vivo.
Topics: Amino Acid Substitution; Animals; Cells, Cultured; Cricetinae; Cyclic AMP; Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Enzymes; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Insulin; Insulin Secretion; Mice; Mice, Obese; Peptide Fragments; Receptors, Glucagon; Spectrometry, Mass, Electrospray Ionization | 2003 |
N-terminal His(7)-modification of glucagon-like peptide-1(7-36) amide generates dipeptidyl peptidase IV-stable analogues with potent antihyperglycaemic activity.
Topics: Animals; Cell Line, Transformed; Cricetinae; Cyclic AMP; Diabetes Mellitus; Dipeptidyl Peptidase 4; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Hypoglycemic Agents; Insulin; Mesocricetus; Mice; Mice, Obese; Peptide Fragments; Protein Precursors; Pyrrolidonecarboxylic Acid | 2004 |
Effect of GLP-1 (glucagon-like peptide 1:7-36 amide) on porcine pancreatic endocrine cell proliferation and insulin secretion.
Topics: Animals; Cell Proliferation; Cells, Cultured; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Peptide Fragments; Potassium; RNA, Messenger; Swine | 2004 |
Effect of GIP, GLP-1, insulin and gastrin on ghrelin release in the isolated rat stomach.
Topics: Animals; Dose-Response Relationship, Drug; Gastric Inhibitory Polypeptide; Gastric Mucosa; Gastrins; Ghrelin; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Insulin; Male; Peptide Fragments; Peptide Hormones; Protein Precursors; Radioimmunoassay; Rats; Rats, Wistar; Somatostatin; Time Factors | 2004 |
Glucagon-like peptide-1 prevents beta cell glucolipotoxicity.
Topics: Apoptosis; Cell Line; Cells, Cultured; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Humans; Islets of Langerhans; NF-kappa B; Nitriles; Palmitic Acid; Peptide Fragments; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Sulfones | 2004 |
Prior in vitro exposure to GLP-1 with or without GIP can influence the subsequent beta cell responsiveness.
Topics: Animals; Drug Combinations; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Insulin; Islets of Langerhans; Male; Peptide Fragments; Protein Precursors; Rats; Rats, Wistar; Receptors, G-Protein-Coupled | 2004 |
Identification of CJC-1131-albumin bioconjugate as a stable and bioactive GLP-1(7-36) analog.
Topics: Amino Acid Sequence; Animals; CHO Cells; Cricetinae; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Maleimides; Molecular Sequence Data; Peptide Fragments; Peptides; Protein Binding; Serum Albumin | 2004 |
Inulin-type fructans modulate gastrointestinal peptides involved in appetite regulation (glucagon-like peptide-1 and ghrelin) in rats.
Topics: Animals; Appetite Regulation; Cecum; Colon; Diet; Eating; Energy Intake; Ghrelin; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Inulin; Male; Organ Size; Peptide Fragments; Peptide Hormones; Proglucagon; Protein Precursors; Rats; Rats, Wistar; RNA, Messenger; Weight Gain | 2004 |
GLP-1 reduces intestinal lymph flow, triglyceride absorption, and apolipoprotein production in rats.
Topics: Animals; Apolipoproteins A; Apolipoproteins B; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Lymph; Male; Peptide Fragments; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Time Factors; Triglycerides | 2005 |
Involvement of endogenous glucagon-like peptide-1(7-36) amide on glycaemia-lowering effect of oligofructose in streptozotocin-treated rats.
Topics: Actins; Animals; Blood Glucose; Colon; Diabetes Mellitus, Experimental; Eating; Fermentation; Food Deprivation; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Tolerance Test; Insulin; Islets of Langerhans; Male; Oligosaccharides; Peptide Fragments; Proglucagon; Proprotein Convertase 1; Protein Precursors; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2005 |
Active metabolite of GLP-1 mediates myocardial glucose uptake and improves left ventricular performance in conscious dogs with dilated cardiomyopathy.
Topics: Animals; Blood Pressure; Cardiomyopathy, Dilated; Consciousness; Coronary Circulation; Dogs; Dose-Response Relationship, Drug; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Heart; Heart Ventricles; Male; Myocardium; Peptide Fragments; Peptides; Stroke Volume; Treatment Outcome; Ventricular Dysfunction, Left | 2005 |
Glucagon-like peptide-1 reduces the pulsatile component of testosterone secretion in healthy males.
Topics: Administration, Oral; Adult; Blood Glucose; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glucose Clamp Technique; Glucose Tolerance Test; Humans; Infusions, Intravenous; Insulin; Leptin; Luteinizing Hormone; Male; Peptide Fragments; Testosterone | 2005 |
Hormonal regulation of leptin receptor expression in primary cultures of porcine hepatocytes.
Topics: Animals; Cyclic AMP; Ghrelin; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Hepatocytes; Insulin; Liver Glycogen; Male; Peptide Fragments; Peptide Hormones; Protein Isoforms; Receptors, Cell Surface; Receptors, Leptin; Reverse Transcriptase Polymerase Chain Reaction; RNA; Triiodothyronine; Up-Regulation | 2005 |
Human duodenal enteroendocrine cells: source of both incretin peptides, GLP-1 and GIP.
Topics: Adult; Aged; Aged, 80 and over; Area Under Curve; Biopsy; Diabetes Mellitus, Type 2; Duodenum; Enteroendocrine Cells; Enzyme-Linked Immunosorbent Assay; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glucose Tolerance Test; Humans; Immunohistochemistry; Insulin; Insulin Resistance; Male; Middle Aged; Peptide Fragments; Reverse Transcriptase Polymerase Chain Reaction | 2006 |
Direct effects of glucagon-like peptide-1 on myocardial contractility and glucose uptake in normal and postischemic isolated rat hearts.
Topics: Animals; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glucose Transporter Type 1; Heart; In Vitro Techniques; Male; Myocardial Contraction; Myocardial Ischemia; Myocardium; Nitric Oxide; Peptide Fragments; Protein Transport; Rats; Rats, Wistar; Ventricular Function, Left | 2006 |
Transcription factor FoxO1 mediates glucagon-like peptide-1 effects on pancreatic beta-cell mass.
Topics: Animals; Cell Division; Cell Line; Cell Survival; Forkhead Box Protein O1; Forkhead Transcription Factors; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Green Fluorescent Proteins; Insulin; Islets of Langerhans; Mice; Mice, Transgenic; Peptide Fragments | 2006 |
Transmembrane α-helix 2 and 7 are important for small molecule-mediated activation of the GLP-1 receptor.
Topics: Cyclic AMP; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; HEK293 Cells; Humans; Ligands; Models, Molecular; Peptide Fragments; Protein Structure, Secondary; Receptors, Glucagon | 2011 |
Plasma concentrations and effects of glucagon-like peptide-1 (7-36) amide in calves before and after weaning.
Topics: Aging; Animal Feed; Animals; Blood Glucose; Cattle; Diet; Fatty Acids, Volatile; Glucagon; Glucagon-Like Peptide 1; Insulin; Male; Milk; Peptide Fragments; Weaning | 2012 |
Impact of glucagon-like peptide-1 (7-36) amide, isosteviol and 5-aminoimidazole-4-carboxamide 1-β-d-ribofuranoside on leucine-mediated α-cell dysfunction.
Topics: Aminoimidazole Carboxamide; Animals; Cells, Cultured; Diterpenes, Kaurane; Dose-Response Relationship, Drug; Female; Gene Expression Regulation; Gene Expression Regulation, Enzymologic; Glucagon; Glucagon-Like Peptide 1; Glucagon-Secreting Cells; Leucine; Mice; Mice, Transgenic; Peptide Fragments; Protein Precursors; Ribonucleosides | 2012 |