Page last updated: 2024-09-04

glucagon and colforsin

glucagon has been researched along with colforsin in 214 studies

Compound Research Comparison

Studies
(glucagon)
Trials
(glucagon)
Recent Studies (post-2010)
(glucagon)
Studies
(colforsin)
Trials
(colforsin)
Recent Studies (post-2010) (colforsin)
26,0391,4983,05413,460461,298

Protein Interaction Comparison

ProteinTaxonomyglucagon (IC50)colforsin (IC50)
nuclear receptor subfamily 0 group B member 1Homo sapiens (human)1.729
5-hydroxytryptamine receptor 1AHomo sapiens (human)0.041
Adenylate cyclase type 1Homo sapiens (human)0.0955

Research

Studies (214)

TimeframeStudies, this research(%)All Research%
pre-199065 (30.37)18.7374
1990's101 (47.20)18.2507
2000's41 (19.16)29.6817
2010's6 (2.80)24.3611
2020's1 (0.47)2.80

Authors

AuthorsStudies
Itoh, N; Ohtani, R; Okamoto, H; Takano, M; Yayama, K1
Amiel, C; Friedlander, G; Herman, P; Huy, PT1
Ishac, EJ; Kunos, G; Lazar-Wesley, E1
Somogyi, R; Stucki, JW; Zhao, M1
Cote, P; Diehl, AM; Wand, GS; Yang, SQ1
Brubaker, PL; Stobie-Hayes, KM2
Absood, A; Chen, D; Håkanson, R1
DeSilva, SE; Nagy, LE1
Bataille, D; Demirpence, E; Gros, L; Jarrousse, C; Kervran, A1
Fehmann, HC; Habener, JF1
Benito, M; de Juan, C; Fabregat, I1
Houslay, MD; Palmer, TM; Taberner, PV1
Gross, R; Hillaire-Buys, D; Loubatières-Mariani, MM; Ribes, G1
Farkas, EM; Papachristou, DN; Patel, YC; Zingg, HH1
Amiel, C; Bernard, C; Ferrary, E; Friedlander, G; Sterkers, O1
Boege, F; Cantrill, RC; Hahn, M; Heithier, H; Kurstjens, NP1
Flores-Riveros, JR; Janicot, M; Kaestner, KH; Lane, MD; McLenithan, JC1
Arnold, R; Bächle, R; Fehmann, HC; Göke, B; Göke, R; Wagner, B1
Classen, M; Fürlinger, C; Janczewska, I; Schepp, W; Schmidtler, J; Schusdziarra, V; Weigert, N1
Jansen, PL; Ottenhoff, R; Oude Elferink, RP; Roelofsen, H1
Berrow, NS; Lacey, RJ; Morgan, NG; Scarpello, JH1
De Cannière, D; Dehaye, JP; Pector, JC; Préat, V; Ravelingien, N1
Houslay, MD; Palmer, TM1
Bolaffi, JL; Grodsky, GM; Ma, YH; Rodd, G1
Brubaker, PL; Campos, R; Drucker, DJ; Reynolds, R; Stobie, K1
Ammon, HP; Anazodo, MI; Müller, AB; Safayhi, H1
Brosnan, JT; Collett, VM; Hall, B; Jois, M1
Garcia-Ruiz, C; Kaplowitz, N; Kuhlenkamp, J; Lu, SC; Ookhtens, M; Salas-Prato, M1
Chow, SC; Duddy, SK; Kass, GE; Llopis, J; Orrenius, S1
Grojec, MS; Ishac, EJ; Kapocsi, J; Kunos, G1
Coezy, ED; Corvol, P; Howlett, AC1
Griffiths, NM; Simmons, NL1
Good, DW1
Harano, Y; Hashimoto, T; Kashiwagi, A; Kojima, H; Shigeta, Y; Suzuki, M1
Danoff, A; Fleischer, N; Pasmantier, R; Schubart, UK1
Blackmore, PF; Exton, JH1
Al-Turk, WA; Othman, S; Shaheen, O1
Hara, M; Ogawa, A; Sasaki, H; Sato, N; Suda, K; Takahashi, K; Wada, K; Wakasugi, K; Yamatani, K1
Kojima, I; Mine, T; Ogata, E1
Boyd, AE; Hill, RS; Rajan, AS1
Baxter, RC; Lewitt, MS1
Chua, BH; Haneda, T; Morgan, HE; Watson, PA; Xenophontos, XP1
Christoffersen, T; Johansen, EJ; Refsnes, M1
Abramovitch, E; Cerasi, E; Nesher, R1
Christoffersen, T; Gjone, IH; Gladhaug, IP; Ostby, E; Refsnes, M; Thoresen, GH1
Katzir, Z; Popovtzer, MM; Rubinger, D; Wald, H1
Blackmore, PF; Exton, JH; Johnson, EH; Krone, PK; Lynch, CJ; Wange, RL1
Grapengiesser, E; Gylfe, E; Hellman, B1
Hamm, MW; Lee, CR1
Brubaker, PL; Drucker, DJ1
Antoine, B; Decaux, JF; Kahn, A1
Griffiths, NM; Rugg, EL; Simmons, NL1
Gawler, DJ; Houslay, MD; Milligan, G; Wilson, A1
Hermansen, K1
Dettmer, D; Hermsdorf, T; Hofmann, E1
Boland, SR; Hymer, TK; Katz, MS; McNair, CL1
Amiel, C; Friedlander, G; Giocondi, MC; Le Grimellec, C1
Ishikawa, S; Okada, K; Saito, T1
Kurokawa, K; Takaichi, K2
García-Sáinz, JA; Hernández-Sotomayor, SM; Macías-Silva, M; Plebañski, M1
Hashimoto, K; Kato, K; Tsujimoto, A; Tsujimoto, G1
Bianchini, L; Fossat, B; Guibbolini, M; Lahlou, B; Porthé-Nibelle, J1
Davis, MS; Shuttleworth, TJ1
Schonbrunn, A; Sullivan, SJ1
Blackmore, PF; Bocckino, SB; Exton, JH; Waynick, LE1
Bloom, AS; Hillard, CJ; Houslay, MD1
Ho, RJ; Ruiz, J; Shi, QH1
Hansford, RG; Staddon, JM1
Bégin-Heick, N; Black, M; Heick, HM1
Blackmore, PF; Bosch, F; Bouscarel, B; Exton, JH; Slaton, J1
Dax, EM; Gregerman, RI; Partilla, JS; Piñeyro, MA1
Hii, CS; Howell, SL2
Hur, KC; Iwanij, V1
Amiel, C; Friedlander, G1
Ramanadham, S; Tenner, TE1
Brelje, TC; Sorenson, RL1
Söling, HD; Thiel, G1
Anand-Srivastava, MB1
Bannasch, P; Ehemann, V; Hacker, HJ; Mayer, D1
Camus, JC; Christophe, J; De Neef, P; Gillard, M; Robberecht, P; Waelbroeck, M1
Ho, RJ; Ruiz, JA1
Ho, RJ; Ruiz, JA; Shi, QH1
Dhillon, GS; Honnor, RC; Londos, C1
Anand-Srivastava, MB; Srivastava, AK1
Hynie, S; Klenerová, V; Wenke, M1
Cook, DL; Ikeuchi, M1
Corvera, S; García-Sáinz, JA; Hruby, VJ; Huerta-Bahena, J; Pelton, JT; Trivedi, D1
Arslan, Y; Iynedjian, PB1
Draznin, B; Leitner, JW; Steinberg, JP; Sussman, KE1
Ho, R; Shi, QH1
Exton, JH; Morgan, NG; Shipp, CC1
Tarui, S1
Ichihara, A; Kato, S; Nakamura, T; Noda, C; Shinjyo, F; Tomomura, A1
Blum, JJ; Leiser, J1
Jungermann, K; Zierz, S1
Birnbaumer, L; Desmier, M; Hanoune, J; Stengel, D1
Ogihara, M1
Dégano, P; Fontela, T; García-Hermida, O; Marco, J; Salas, M; Silvestre, RA1
Abrahamsen, N; Nishimura, E1
Asa, SL; Brubaker, PL; Drucker, DJ; Jin, T; Young, TA1
Absood, A; Maruno, K; Said, SI1
Hinds, TR; Storm, DR; Wayman, GA1
Alvaro, D; Bini, A; Capocaccia, L; Della Guardia, P; Furfaro, S; Gigliozzi, A; La Rosa, T; Piat, C1
Drucker, DJ; Gajic, D1
Göke, B; Göke, R; McGregor, GP1
Kong, X; Lawrence, JC; Sevetson, BR1
Bogoyevitch, MA; Fuller, SJ; Sugden, PH1
Omiecinski, CJ; Sidhu, JS1
Bokvist, K; Dissing, S; Frøkjaer-Jensen, J; Gromada, J; Renström, E; Rorsman, P; Wulff, BS1
Marubashi, S; Saito, K; Sasaki, H; Sato, N; Takahashi, K; Wakasugi, K; Yamatani, K1
Bray, TM; Goss, PM; Nagy, LE; Rozwadowski, M; Stephen, LL1
Fehmann, HC; Göke, B; Strowski, M1
Arilla, E; Carrero, I; Couvineau, A; Guijarro, LG; Laburthe, M; Prieto, JC; Rodriguez-Henche, N1
Chen, S; Stucki, JW; Ubl, JJ1
Houslay, MD; Livingstone, C; MacDonald, C; Willett, B1
Bushfield, M; Houslay, MD; Lavan, BE; Morris, NJ1
Abello, J; Bernard, C; Bosshard, A; Chayvialle, JA; Cuber, JC; Ye, F1
Cherkasova, TD; Iurkiv, VA1
Classen, M; Dehne, K; Offermanns, S; Rosenthal, W; Schepp, W; Schmidtler, J1
Meijer, DK; Merema, M; Nijholt, A; Smit, H; Steen, H1
Cobbold, PH; Marrero, I; Sanchez-Bueno, A1
Cortinovis, C; Klimek, F; Nogueira, E1
Garcia-Jimenez, C; Hernandez, A; Obregon, MJ; Santisteban, P1
Ramírez, I; Soley, M; Tebar, F1
Brunner, HR; Grouzmann, E; Nicod, P; Thompson, N; Waeber, B; Waeber, G1
Christoffersen, T; Jacobsen, FW; Refsnes, M; Sandnes, D1
Bahouth, SW; Betts, D; Fain, JN; Kang, ES; Myers, LK1
Kuestner, RE; Moore, EE; Stroop, SD; Thompson, DL1
Buggy, JJ; Heurich, RO; Rossomando, AJ; Vandenberg, MT1
Gordon, PB; Holen, I; Seglen, PO; Strømhaug, PE1
Hanafusa, T; Kuwajima, M; Matsumura, T; Matsuzawa, Y; Miki, H; Mineo, I; Miyagawa, J; Nakajima, H; Namba, M; Nishimura, T1
Laychock, SG1
Göke, B; Göke, R; Steffen, H1
Díaz-Laviada, I; Guillén, A; Haro, A; Nieto, JL1
Fehmann, HC; Göke, B; Jiang, J; Pitt, D; Schweinfurth, J1
Hernández, ML; Martínez, MJ; Ochoa, B; Ruiz, JI1
Andreani-Mangeney, M; Bereziat, G; Girlich, D; Janvier, B; Vandenbrouck, Y1
Dove, J; Matheny, M; Scarpace, PJ1
Boissard, C; Chastre, E; Marie, JC; Phan, HH; Rosselin, G1
Ding, WG; Gromada, J1
Haneda, T; Kikuchi, K; Osaki, J; Sakai, H1
Seidler, FJ; Slotkin, TA; Zeiders, JL1
Christ, B; Jungermann, K; Nath, A1
Leclercq-Meyer, V; Malaisse, WJ1
Bouscarel, B; Ceryak, S; Fromm, H; Gettys, TW; Le, M; Matsuzaki, Y; Shoda, J1
Ceppi, ED; Smith, FS; Titheradge, MA1
Bokvist, K; Ding, WG; Gromada, J; Holst, JJ; Nielsen, JH; Rorsman, P1
Hild, M; Schaller, H; Weber, O1
Buchan, AM; Damholt, AB; Kofod, H1
Nakata, M; Tanaka, H; Yada, T; Yaekura, K1
Bannasch, P; Klimek, F; Mayer, D1
Abello, J; Bosshard, A; Chayvialle, JA; Chevrier, AM; Cuber, JC; Saïfia, S1
Bouscarel, B; Fromm, H; Gettys, TW; Le, M; Matsuzaki, Y1
Bapty, BW; Canaff, L; Dai, LJ; Hendy, GN; Quamme, GA; Ritchie, G1
Fehmann, HC; Göke, B; Pracht, A1
Fukuzawa, J; Haneda, T; Kashiwagi, Y; Kikuchi, K; Oi, S; Osaki, J; Sakai, H1
Chen, D; Håkanson, R; Lundquist, I; Nordin, G; Salehi, A1
Bali, JP; Bataille, D; Geneviève, R; Jarrousse, C; Le Nguyen, D; Magous, R; Martinez, J; Mochizuki, T; Rodier, G1
Fujioka, T; Ishibashi, K; Ui, M1
Andreis, PG; Malendowicz, LK; Neri, G; Nussdorfer, GG; Tortorella, C1
Belin, VD; Clayton, HA; Green, IC; James, RF; Mabley, JG; Swift, SM; Titheradge, MA1
Ahrén, B; Havel, PJ1
Anand-Srivastava, MB; Garcia, R; Ge, C2
Ahrén, B; Karlsson, S; Simonsson, E1
Bizeau, ME; Hazel, JR1
Aust, G; Nguyen, TB; Scherbaum, WA; Seissler, J; Steinbrenner, H1
Albertin, G; Aragona, F; Gottardo, L; Mazzocchi, G; Nussdorfer, GG1
Anand-Srivastava, MB; Di Fusco, F; Hashim, S1
Daniel, PB; Habener, JF; Hussain, MA1
Bjurholm, A; Horton, MA; Lehenkari, PP; Lerner, UH; Lie, A; Lundberg, P; Ransjö, M1
Niki, I; Nimura, Y; Niwa, T1
Brubaker, PL; Dhanvantari, S; Izzo, A; Jansen, E1
Manaka, H; Ohnuma, H; Saito, K; Sasaki, H; Takahashi, K; Yamatani, K1
Chen, Q; Iber, H; Li-Masters, T; Morgan, ET; Yu, S1
Cerasi, E; Efendic, S; Kaiser, N; Khan, A; Nesher, R; Warwar, N1
Alm, P; Henningsson, R; Lundquist, I1
Armatis, P; Csernus, B; Groot, K; Halmos, G; Plonowski, A; Rekasi, Z; Schally, AV; Varga, JL1
Ganster, RW; Geller, DA; Harbrecht, BG; Ramalakshmi, S; Taylor, BS; Xu, Z1
Lopez, M; Mazzeo, RS; Podolin, DA; Roth, DA; Wills, BK; Wood, IO1
Bouscarel, B; Cypess, AM; Ikegami, T1
Aizawa, T; Hashizume, K; Komatsu, M; Sato, Y; Yamada, S; Yamauchi, K1
Bhatt, HS; Easom, RA; Lawrence, MC1
Kirchgessner, AL; Ouedraogo, R; Tong, Q1
Civelek, VN; Corkey, BE; Cunningham, BA; Daley, JT; Deeney, JT; Dillon, JS; Richard, AM; Tornheim, K; Yaney, GC1
Aizawa, T; Hashizume, K; Kojima, I; Komatsu, M; Sato, Y; Yamada, S; Yamauchi, K1
Drucker, DJ; Halban, PA; Hansotia, T; Li, Y; Ris, F; Yusta, B1
da Silva Xavier, G; Holz, GG; Jouaville, LS; Rutter, GA; Thomas, AP; Tsuboi, T1
Lee, JW; Romsos, DR; Swick, AG1
Bojanowska, E; Stempniak, B1
Abdel-Halim, SM; Ahrén, B; Efendic, S; Ljungberg, O; Lukinius, A; Portela-Gomes, GM1
Canettieri, G; Jhala, US; Krajewski, S; Kulkarni, RN; Lin, X; Montminy, M; Reed, J; Screaton, RA; Walker, J; White, M1
Julien, S; Lainé, J; Morisset, J1
Göpel, SO; Holm, C; Olofsson, CS; Rorsman, P; Salehi, A1
Ficarro, S; Grossman, LI; Hüttemann, M; Lee, I; Lottspeich, F; Mathes, I; Salomon, AR1
Boer, P; Sperling, O1
Liu, C; Shen, P; Zhang, C; Zhang, CY; Zhang, J; Zhang, P; Zhang, Y1
Korol'kov, VI; Kuznetsova, LA; Pertseva, MN; Plesneva, SA; Shpakov, AO1
Andrade, CF; Brubaker, PL; Chen, L; Dubé, PE; Jin, T; Liu, M; Wang, P; Zhao, IY1
Becker, TC; Cao, W; Collins, QF; Collins, S; Daniel, KW; Floering, L; Lupo, EG; Robidoux, J; Xiong, Y1
Farghali, H; Hodis, J; Kmoníčková, E; Kutinová-Canová, N; Potmesil, P; Zídek, Z1
Amiel, SA; Brereton, H; Huang, GC; Jones, PM; Muller, DS; Persaud, SJ; Ramracheya, RD; Squires, PE; Sugden, D1
Christ, B1
Xie, X; Xu, Y1
Abdulkader, F; Amisten, S; Bengtsson, M; Braha, O; Braun, M; De Marinis, YZ; Eliasson, L; Gribble, F; Habib, AM; Moritoh, Y; Ramracheya, R; Reimann, F; Renström, E; Rorsman, P; Rosengren, A; Salehi, A; Seino, S; Shibasaki, T; Ward, CE; Zhang, E; Zhang, Q1
Alonge, KM; Cyphert, HA; Hillgartner, FB; Ippagunta, SM1
Bertile, F; Chilloux, J; Delalande, F; Gautier-Stein, A; Mithieux, G; Soty, M; Zitoun, C1
Edlund, A; Eliasson, L; Flodström-Tullberg, M; Lindqvist, A; Pedersen, MG; Wierup, N1
Bosco, D; Dibner, C; Gachon, F; Giovannoni, L; Gobet, C; Gu, G; Heddad Masson, M; Petrenko, V; Philippe, J; Sage, D; Saini, C; Unser, M1
Goldberg, AL; Lokireddy, S; VerPlank, JJS; Zhao, J1
Ameneiro, C; Beiroa, D; Bernardo, G; Bilbao, J; Bravo, SB; Carneiro, C; Cho, JW; Coppari, R; Cuñarro, J; Da Silva Lima, N; Dieguez, C; Dp Chantada-Vazquez, M; Fernandez, U; Fernández-Ramos, D; Ferno, J; Fidalgo, M; Fondevila, MF; Fruhbeck, G; Garcia-Vence, M; Gonzalez-Rellan, MJ; Guallar, D; Herzig, S; Iglesias, C; López, M; Lopitz-Otsoa, F; Martinez-Chantar, ML; Mato, JM; Millet, O; Müller, TD; Nogueiras, R; Novoa, E; Perez-Fernandez, R; Porteiro, B; Rodríguez, A; Sabio, G; Senra, A; Seoane, S; Tovar, S; Varela-Rey, M; Veyrat-Durebex, C; Vidal, A; Woodhoo, A; Yang, WH1

Other Studies

214 other study(ies) available for glucagon and colforsin

ArticleYear
Stimulation of angiotensinogen production in primary cultures of rat hepatocytes by glucocorticoid, cyclic adenosine 3',5'-monophosphate, and interleukin-6.
    Endocrinology, 1992, Volume: 130, Issue:3

    Topics: Angiotensinogen; Animals; Bucladesine; Cells, Cultured; Colforsin; Cyclic AMP; Cytokines; Dexamethasone; DNA; DNA, Neoplasm; Dose-Response Relationship, Drug; Estrogens; Gene Expression; Glucagon; Glucocorticoids; Interleukin-6; Liver; Liver Neoplasms, Experimental; Male; Rats; Rats, Inbred Strains; Triiodothyronine; Tumor Cells, Cultured

1992
Ion transport by primary cultures of Mongolian gerbil middle ear epithelium.
    The American journal of physiology, 1992, Volume: 262, Issue:3 Pt 2

    Topics: Amiloride; Animals; Arginine Vasopressin; Biological Transport; Bradykinin; Cell Membrane; Cell Membrane Permeability; Cells, Cultured; Chlorides; Colforsin; Cyclic AMP; Dinoprostone; Ear, Middle; Epithelium; Gerbillinae; Glucagon; Histamine; Indomethacin; Isoproterenol; Male; Mannitol; Microscopy, Electron; Parathyroid Hormone; Sodium

1992
Rapid inverse changes in alpha 1B- and beta 2-adrenergic receptors and gene transcripts in acutely isolated rat liver cells.
    Journal of cellular physiology, 1992, Volume: 152, Issue:1

    Topics: Animals; Cells, Cultured; Colforsin; Cyclic AMP; Cycloheximide; Glucagon; Inositol 1,4,5-Trisphosphate; Isoproterenol; Liver; Male; Phenylephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; RNA, Messenger; Time Factors; Transcription, Genetic

1992
Modulation of cytosolic-[Ca2+] oscillations in hepatocytes results from cross-talk among second messengers. The synergism between the alpha 1-adrenergic response, glucagon and cyclic AMP, and their antagonism by insulin and diacylglycerol manifest themsel
    The Biochemical journal, 1992, Sep-15, Volume: 286 ( Pt 3)

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Benzimidazoles; Calcium; Calmodulin; Cations, Divalent; Cells, Cultured; Colforsin; Cyclic AMP; Cytosol; Diglycerides; Drug Synergism; Glucagon; Imidazoles; Insulin; Liver; Phenylephrine; Protein Kinase C; Rats; Second Messenger Systems; Thionucleotides

1992
Chronic ethanol consumption disturbs G-protein expression and inhibits cyclic AMP-dependent signaling in regenerating rat liver.
    Hepatology (Baltimore, Md.), 1992, Volume: 16, Issue:5

    Topics: Adenylyl Cyclases; Animals; Cell Membrane; Colforsin; Cyclic AMP; Enzyme Activation; Ethanol; Gene Expression; Glucagon; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Liver; Liver Regeneration; Male; Phosphoenolpyruvate Carboxykinase (GTP); Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction

1992
Control of proglucagon-derived peptide synthesis and secretion in fetal rat hypothalamus.
    Neuroendocrinology, 1992, Volume: 56, Issue:3

    Topics: Animals; Bucladesine; Cells, Cultured; Colforsin; Enzyme Activation; Fetal Proteins; Glucagon; Hypothalamus; Neuropeptides; Proglucagon; Protein Kinase C; Protein Kinases; Protein Precursors; Radioimmunoassay; Rats; Tetradecanoylphorbol Acetate

1992
Neuropeptides of the vasoactive intestinal peptide/helodermin/pituitary adenylate cyclase activating peptide family elevate plasma cAMP in mice: comparison with a range of other regulatory peptides.
    Regulatory peptides, 1992, Aug-13, Volume: 40, Issue:3

    Topics: Animals; Calcitonin; Calcitonin Gene-Related Peptide; Colforsin; Cyclic AMP; Drug Interactions; Glucagon; In Vitro Techniques; Intercellular Signaling Peptides and Proteins; Mice; Neuropeptides; Parathyroid Hormone; Peptides; Phosphodiesterase Inhibitors; Pyrrolidinones; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Rolipram; Tail; Vasoactive Intestinal Peptide

1992
Ethanol increases receptor-dependent cyclic AMP production in cultured hepatocytes by decreasing G(i)-mediated inhibition.
    The Biochemical journal, 1992, Sep-15, Volume: 286 ( Pt 3)

    Topics: Alcohol Dehydrogenase; Animals; Blotting, Western; Cells, Cultured; Colforsin; Cyclic AMP; Ethanol; Glucagon; GTP-Binding Proteins; Liver; Rats; Receptors, Purinergic; Somatostatin

1992
Characterization of binding sites for oxyntomodulin on a somatostatin-secreting cell line (RIN T3).
    Endocrinology, 1992, Volume: 130, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Animals; Binding Sites; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Glucagon; Glucagon-Like Peptides; Insulinoma; Iodine Radioisotopes; Oxyntomodulin; Rats; Somatostatin; Tumor Cells, Cultured

1992
Galanin inhibits proinsulin gene expression stimulated by the insulinotropic hormone glucagon-like peptide-I(7-37) in mouse insulinoma beta TC-1 cells.
    Endocrinology, 1992, Volume: 130, Issue:5

    Topics: Adenylate Cyclase Toxin; Animals; Blotting, Northern; Cell Line; Chloramphenicol O-Acetyltransferase; Colforsin; Galanin; Gene Expression; Gene Expression Regulation, Neoplastic; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Insulinoma; Kinetics; Mice; Models, Biological; Pancreatic Neoplasms; Peptide Fragments; Peptides; Pertussis Toxin; Proinsulin; RNA, Neoplasm; Transfection; Virulence Factors, Bordetella

1992
Regulation of albumin expression in fetal rat hepatocytes cultured under proliferative conditions: role of epidermal growth factor and hormones.
    Journal of cellular physiology, 1992, Volume: 152, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Albumins; Animals; Cell Division; Cells, Cultured; Colforsin; Cyclic AMP; Dexamethasone; Epidermal Growth Factor; Fetus; Gene Expression Regulation; Glucagon; Liver; Norepinephrine; Phorbol Esters; Rats; Rats, Inbred Strains; RNA, Messenger; Signal Transduction; Time Factors; Vasopressins

1992
Alterations in G-protein expression, Gi function and stimulatory receptor-mediated regulation of adipocyte adenylyl cyclase in a model of insulin-resistant diabetes with obesity.
    Cellular signalling, 1992, Volume: 4, Issue:4

    Topics: Adenylyl Cyclases; Adipose Tissue; Animals; Cell Membrane; Cells, Cultured; Colforsin; Diabetes Mellitus; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucagon; GTP-Binding Proteins; Isoproterenol; Magnesium; Mice; Mice, Inbred CBA; Obesity; Secretin

1992
Diabetes alters the responses of glucagon secreting cells and vascular bed to isoprenaline and forskolin in vitro in rat pancreas.
    Life sciences, 1991, Volume: 48, Issue:24

    Topics: Adenylyl Cyclases; Animals; Blood Flow Velocity; Colforsin; Diabetes Mellitus, Experimental; Glucagon; Insulin; Isoproterenol; Kinetics; Male; Pancreas; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vasodilation

1991
Regulation of islet somatostatin secretion and gene expression: selective effects of adenosine 3',5'-monophosphate and phorbol esters in normal islets of Langerhans and in a somatostatin-producing rat islet clonal cell line 1027 B2.
    Endocrinology, 1991, Volume: 128, Issue:4

    Topics: Adenoma, Islet Cell; Animals; Animals, Newborn; Bucladesine; Colforsin; Cyclic AMP; Gene Expression Regulation; Glucagon; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Phorbol Esters; Rats; Rats, Inbred Strains; RNA, Messenger; Somatostatin; Theophylline; Tumor Cells, Cultured

1991
Antidiuretic hormone stimulation of adenylate cyclase in semicircular canal epithelium.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 1991, Volume: 248, Issue:5

    Topics: Adenylyl Cyclases; Adrenergic alpha-Agonists; Animals; Calcitonin; Clonidine; Colforsin; Cyclic AMP; Dinoprostone; Endolymph; Epithelium; Glucagon; Isoproterenol; Norepinephrine; Organ Culture Techniques; Parathyroid Hormone; Rana esculenta; Semicircular Canals; Vasopressins; Vasotocin

1991
Multiple hormone actions: the rises in cAMP and Ca++ in MDCK-cells treated with glucagon and prostaglandin E1 are independent processes.
    Biochemical and biophysical research communications, 1990, Mar-30, Volume: 167, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Animals; Calcium; Carbachol; Cell Line; Colforsin; Cyclic AMP; Dogs; Fluorescent Dyes; Glucagon; Indoles; Isoproterenol; Kidney; Kinetics; Receptors, Gastrointestinal Hormone; Receptors, Glucagon

1990
Transcriptional repression of the mouse insulin-responsive glucose transporter (GLUT4) gene by cAMP.
    Proceedings of the National Academy of Sciences of the United States of America, 1991, Mar-01, Volume: 88, Issue:5

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adipose Tissue; Animals; Antisense Elements (Genetics); Cell Line; Cell Nucleus; Colforsin; Cyclic AMP; Deoxyglucose; Glucagon; Isoproterenol; Kinetics; Mice; Monosaccharide Transport Proteins; RNA; Transcription, Genetic

1991
Priming effect of glucagon-like peptide-1 (7-36) amide, glucose-dependent insulinotropic polypeptide and cholecystokinin-8 at the isolated perfused rat pancreas.
    Biochimica et biophysica acta, 1991, Feb-19, Volume: 1091, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Line; Colforsin; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; In Vitro Techniques; Islets of Langerhans; Kinetics; Male; Peptide Fragments; Peptides; Perfusion; Rats; Rats, Inbred Strains; Sincalide

1991
GLP-1-(7-36) amide, -(1-37), and -(1-36) amide: potent cAMP-dependent stimuli of rat parietal cell function.
    The American journal of physiology, 1991, Volume: 260, Issue:6 Pt 1

    Topics: 1-Methyl-3-isobutylxanthine; Aminopyrine; Animals; Biological Transport; Bucladesine; Carbachol; Colforsin; Cyclic AMP; Female; Gastric Acid; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Histamine; In Vitro Techniques; Inositol Phosphates; Kinetics; Parietal Cells, Gastric; Peptide Fragments; Peptides; Pertussis Toxin; Rats; Rats, Inbred Strains; Virulence Factors, Bordetella

1991
Hepatocanalicular organic-anion transport is regulated by protein kinase C.
    The Biochemical journal, 1991, Sep-15, Volume: 278 ( Pt 3)

    Topics: 1-Methyl-3-isobutylxanthine; Alkaloids; Animals; Anion Transport Proteins; Anions; Bile Canaliculi; Biological Transport; Bucladesine; Carrier Proteins; Colforsin; Cyclic AMP; Glucagon; Glutathione; Male; Protein Kinase C; Rats; Rats, Inbred Strains; Second Messenger Systems; Staurosporine; Tetradecanoylphorbol Acetate; Vasopressins

1991
Selective stimulation of glucagon secretion by beta 2-adrenoceptors in isolated islets of Langerhans of the rat.
    British journal of pharmacology, 1991, Volume: 103, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Antagonists; Animals; Atenolol; Clenbuterol; Colforsin; Cyclic AMP; Glucagon; In Vitro Techniques; Insulin; Islets of Langerhans; Male; Propanolamines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta

1991
Adenylate cyclase activity in crude liver membranes during chemical hepatocarcinogenesis in portacaval shunted rats.
    Carcinogenesis, 1992, Volume: 13, Issue:2

    Topics: 2-Acetylaminofluorene; Adenylyl Cyclases; Animals; Cell Membrane; Colforsin; Diethylnitrosamine; Glucagon; Guanine Nucleotides; Liver; Liver Neoplasms, Experimental; Male; Portacaval Shunt, Surgical; Rats; Rats, Inbred Strains

1992
Determination of G-protein levels, ADP-ribosylation by cholera and pertussis toxins and the regulation of adenylyl cyclase activity in liver plasma membranes from lean and genetically diabetic (db/db) mice.
    Biochimica et biophysica acta, 1991, Oct-21, Volume: 1097, Issue:3

    Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Blotting, Western; Cell Membrane; Cholera Toxin; Colforsin; Diabetes Mellitus, Experimental; Glucagon; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Liver; Male; Mice; Mice, Inbred C57BL; Pertussis Toxin; Virulence Factors, Bordetella

1991
Effect of glucagon or somatostatin on desensitized insulin secretion.
    Endocrinology, 1990, Volume: 126, Issue:3

    Topics: Animals; B-Lymphocytes; Colforsin; Glucagon; In Vitro Techniques; Insulin; Insulin Secretion; Male; Rats; Rats, Inbred Strains; Somatostatin; Time Factors

1990
The rat glucagon gene is regulated by a protein kinase A-dependent pathway in pancreatic islet cells.
    Endocrinology, 1991, Volume: 128, Issue:1

    Topics: Animals; Base Sequence; Cell Line; Cells, Cultured; Chromosome Deletion; Colforsin; Gene Expression Regulation; Glucagon; Glucose; Islets of Langerhans; Male; Molecular Sequence Data; Protein Kinase C; Rats; Rats, Inbred Strains; RNA, Messenger; Transcription, Genetic; Transfection

1991
Potentiation of forskolin-induced increase of cAMP by diamide and N-ethylmaleimide in rat pancreatic islets.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1990, Volume: 22, Issue:2

    Topics: Animals; Azo Compounds; Colforsin; Cyclic AMP; Diamide; Drug Synergism; Enzyme Induction; Ethylmaleimide; Glucagon; Islets of Langerhans; Rats

1990
Flux through glycine cleavage system in isolated hepatocytes: effects of glucagon, cAMP, and calcium.
    Biochemistry and cell biology = Biochimie et biologie cellulaire, 1990, Volume: 68, Issue:2

    Topics: Animals; Bucladesine; Calcium; Colforsin; Cyclic AMP; Glucagon; Glycine; In Vitro Techniques; Liver; Male; Rats; Rats, Inbred Strains; Theophylline

1990
Hormonal regulation of glutathione efflux.
    The Journal of biological chemistry, 1990, Sep-25, Volume: 265, Issue:27

    Topics: Animals; Bucladesine; Cells, Cultured; Colforsin; Cyclic AMP; Glucagon; Glutathione; Hormones; Kinetics; Liver; Male; Methionine; Phenylephrine; Rats; Rats, Inbred Strains; Vasopressins

1990
Receptor-operated calcium influx in rat hepatocytes. Identification and characterization using manganese.
    The Journal of biological chemistry, 1990, Oct-15, Volume: 265, Issue:29

    Topics: Angiotensin II; Animals; Bucladesine; Calcium; Cells, Cultured; Colforsin; Fura-2; Glucagon; Hormones; Kinetics; Liver; Male; Manganese; Membrane Potentials; Nickel; Pertussis Toxin; Rats; Rats, Inbred Strains; Signal Transduction; Spectrometry, Fluorescence; Vasopressins; Virulence Factors, Bordetella

1990
The effect of essential fatty acid deficiency on the adrenergic activation of glycogenolysis in rat hepatocytes.
    Archives of biochemistry and biophysics, 1990, Nov-15, Volume: 283, Issue:1

    Topics: Animals; Cells, Cultured; Colforsin; Cyclic AMP; Epinephrine; Fatty Acids, Essential; Fatty Acids, Unsaturated; Female; Glucagon; Isoproterenol; Kinetics; Liver; Liver Glycogen; Melitten; Phenylephrine; Phosphorylase a; Pregnancy; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Reference Values

1990
Involvement of a pertussis toxin-sensitive G protein in the regulation of angiotensinogen production by an angiotensin II analog in HepG2 cells.
    Cellular signalling, 1990, Volume: 2, Issue:1

    Topics: Adenosine Diphosphate Ribose; Angiotensin II; Angiotensinogen; Carcinoma, Hepatocellular; Colforsin; Cyclic AMP; Glucagon; GTP-Binding Proteins; Humans; Liver Neoplasms; Neoplasm Proteins; Pertussis Toxin; Protein Processing, Post-Translational; Second Messenger Systems; Tumor Cells, Cultured; Virulence Factors, Bordetella

1990
Vasoactive intestinal peptide stimulation of adenylate cyclase activity in isolated rabbit renal arterial microvessels.
    Experimental physiology, 1990, Volume: 75, Issue:4

    Topics: Adenylyl Cyclases; Animals; Capillaries; Colforsin; Glucagon; In Vitro Techniques; Kidney; Male; Parathyroid Hormone; Prostaglandins E; Rabbits; Vasoactive Intestinal Peptide

1990
Inhibition of bicarbonate absorption by peptide hormones and cyclic adenosine monophosphate in rat medullary thick ascending limb.
    The Journal of clinical investigation, 1990, Volume: 85, Issue:4

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Absorption; Ammonia; Animals; Arginine Vasopressin; Bicarbonates; Biological Transport; Colforsin; Furosemide; Glucagon; In Vitro Techniques; Kidney Medulla; Kidney Tubules; Loop of Henle; Male; Parathyroid Hormone; Rats; Rats, Inbred Strains; Sodium Chloride

1990
Phosphorylation of carnitine palmitoyltransferase and activation by glucagon in isolated rat hepatocytes.
    FEBS letters, 1985, Sep-02, Volume: 188, Issue:2

    Topics: Acyltransferases; Animals; Autoradiography; Carnitine O-Palmitoyltransferase; Colforsin; Diterpenes; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Glucagon; Immunochemistry; In Vitro Techniques; Insulin; Ketone Bodies; Liver; Peptides; Phosphorylation; Rats; Staining and Labeling

1985
P19, a hormonally regulated phosphoprotein of peptide hormone-producing cells: secretagogue-induced phosphorylation in AtT-20 mouse pituitary tumor cells and in rat and hamster insulinoma cells.
    Endocrinology, 1986, Volume: 119, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenoma, Islet Cell; Adrenocorticotropic Hormone; Animals; Colforsin; Corticotropin-Releasing Hormone; Cricetinae; Cyclic AMP; Electrophoresis, Polyacrylamide Gel; Glucagon; Insulinoma; Isoproterenol; Pancreatic Neoplasms; Phosphoproteins; Phosphorylation; Pituitary Neoplasms; Potassium; Rats; Tetradecanoylphorbol Acetate

1986
Studies on the hepatic calcium-mobilizing activity of aluminum fluoride and glucagon. Modulation by cAMP and phorbol myristate acetate.
    The Journal of biological chemistry, 1986, Aug-25, Volume: 261, Issue:24

    Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Adrenergic alpha-Agonists; Aluminum; Aluminum Compounds; Angiotensin II; Calcium; Colforsin; Cyclic AMP; Drug Synergism; Fluorides; Glucagon; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Liver; Pertussis Toxin; Phorbols; Protein Kinase C; Sodium Fluoride; Tetradecanoylphorbol Acetate; Thionucleotides; Vasopressins; Virulence Factors, Bordetella

1986
Effect of forskolin on cAMP accumulation and ketogenesis in isolated hepatocytes.
    General pharmacology, 1986, Volume: 17, Issue:5

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Colforsin; Cyclic AMP; Glucagon; Hypothyroidism; In Vitro Techniques; Ketone Bodies; Liver; Male; Rats

1986
Two types of hormone-responsive adenylate cyclase in the rat liver.
    Biochimica et biophysica acta, 1987, Nov-12, Volume: 931, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Colforsin; Glucagon; Glucose; In Vitro Techniques; Insulin; Kinetics; Liver; Liver Glycogen; Male; Oxymetazoline; Perfusion; Rats; Rats, Inbred Strains; Secretin

1987
Evidence of cyclic AMP-independent action of glucagon on calcium mobilization in rat hepatocytes.
    Biochimica et biophysica acta, 1988, Jun-30, Volume: 970, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Aequorin; Angiotensin II; Animals; Calcium; Colforsin; Cyclic AMP; Glucagon; Liver; Rats; Vasopressins

1988
Effect of rise in cAMP levels on Ca2+ influx through voltage-dependent Ca2+ channels in HIT cells. Second-messenger synarchy in beta-cells.
    Diabetes, 1989, Volume: 38, Issue:7

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Benzofurans; Calcium; Calcium Channels; Cell Line; Cells, Cultured; Colforsin; Cyclic AMP; Electrophysiology; Fura-2; Glucagon; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Second Messenger Systems; Verapamil

1989
Regulation of growth hormone-independent insulin-like growth factor-binding protein (BP-28) in cultured human fetal liver explants.
    The Journal of clinical endocrinology and metabolism, 1989, Volume: 69, Issue:2

    Topics: Amniotic Fluid; Carrier Proteins; Colforsin; Culture Techniques; Cycloheximide; Dexamethasone; Fetus; Glucagon; Glucose; Humans; Immunochemistry; Insulin; Insulin-Like Growth Factor Binding Proteins; Liver; Theophylline

1989
Increased cyclic AMP content accelerates protein synthesis in rat heart.
    Circulation research, 1989, Volume: 65, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Carbon Radioisotopes; Colforsin; Cyclic AMP; Glucagon; Heart; In Vitro Techniques; Insulin; Kinetics; Male; Myocardial Contraction; Myocardium; Perfusion; Phenylalanine; Protein Biosynthesis; Protein Kinases; Radioisotope Dilution Technique; Rats; Rats, Inbred Strains; Tetrodotoxin; Theophylline

1989
Glucagon-induced refractoriness of hepatocyte adenylate cyclase: comparison of homologous and heterologous components and evidence against a role of cAMP.
    Pharmacology & toxicology, 1989, Volume: 64, Issue:5

    Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Animals; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Glucagon; Isoproterenol; Liver; Male; Rats; Rats, Inbred Strains

1989
Reduced early and late phase insulin response to glucose in isolated spiny mouse (Acomys cahirinus) islets: a defective link between glycolysis and adenylate cyclase.
    Diabetologia, 1989, Volume: 32, Issue:9

    Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Female; Glucagon; Glucose; Glycolysis; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Muridae; Rats; Rats, Inbred Strains

1989
Studies of glucocorticoid enhancement of the capacity of hepatocytes to accumulate cyclic AMP.
    Pharmacology & toxicology, 1989, Volume: 65, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Colforsin; Cyclic AMP; Cycloheximide; Dexamethasone; Glucagon; Glucocorticoids; Isoproterenol; Kinetics; Liver; Male; Methylprednisolone; Phosphoric Diester Hydrolases; Rats; Rats, Inbred Strains

1989
Effect of heparin on cortical adenylate cyclase activity and on urinary excretion of 3',5'-adenosine monophosphate in rat.
    Mineral and electrolyte metabolism, 1989, Volume: 15, Issue:6

    Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Dextran Sulfate; Dextrans; Glucagon; Heparin; Kidney Cortex; Magnesium; Parathyroid Hormone; Rats; Sodium Fluoride

1989
Guanine nucleotide binding regulatory proteins and adenylate cyclase in livers of streptozotocin- and BB/Wor-diabetic rats. Immunodetection of Gs and Gi with antisera prepared against synthetic peptides.
    The Journal of clinical investigation, 1989, Volume: 83, Issue:6

    Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Aluminum; Angiotensin II; Animals; Catalysis; Cell Line; Cell Membrane; Cholera Toxin; Colforsin; Diabetes Mellitus, Experimental; Enzyme Activation; Fluorine; Glucagon; GTP-Binding Proteins; Guanosine Triphosphate; Immune Sera; Injections, Intraperitoneal; Liver; Male; Peptide Fragments; Pertussis Toxin; Rats; Rats, Inbred BB; Rats, Inbred Strains; Virulence Factors, Bordetella

1989
Three types of cytoplasmic Ca2+ oscillations in stimulated pancreatic beta-cells.
    Archives of biochemistry and biophysics, 1989, Volume: 268, Issue:1

    Topics: Adenosine Triphosphate; Animals; Benzofurans; Calcium; Carbachol; Colforsin; Cyclic AMP; Cytoplasm; Fura-2; Glucagon; Glucose; In Vitro Techniques; Islets of Langerhans; Kinetics; Mice; Mice, Obese; Rats; Theophylline

1989
Effect of dietary fat and cholesterol supplements on glucagon receptor binding and adenylate cyclase activity of rat liver plasma membrane.
    The Journal of nutrition, 1989, Volume: 119, Issue:4

    Topics: Adenylyl Cyclases; Animals; Cell Membrane; Cholesterol, Dietary; Colforsin; Corn Oil; Dietary Fats; Fish Oils; Glucagon; Liver; Male; Rats; Rats, Inbred Strains; Receptors, Gastrointestinal Hormone; Receptors, Glucagon; Sodium Fluoride

1989
Proglucagon gene expression is regulated by a cyclic AMP-dependent pathway in rat intestine.
    Proceedings of the National Academy of Sciences of the United States of America, 1989, Volume: 86, Issue:11

    Topics: Animals; Base Sequence; Bombesin; Bucladesine; Cholera Toxin; Colforsin; Cyclic AMP; DNA; Fetus; Gene Expression Regulation; Genes; Glucagon; Intestinal Mucosa; Kinetics; Molecular Sequence Data; Proglucagon; Protein Precursors; Rats; Rats, Inbred Strains; RNA, Messenger; Transcription, Genetic

1989
Regulation of the expression of the L-type pyruvate kinase gene in adult rat hepatocytes in primary culture.
    The Journal of biological chemistry, 1989, Jul-15, Volume: 264, Issue:20

    Topics: Animals; Blotting, Northern; Cells, Cultured; Colforsin; Cyclic AMP; Dactinomycin; Gene Expression Regulation; Glucagon; Glucose; Hormones; Insulin; Isoenzymes; Kinetics; Liver; Pyruvate Kinase; Rats; RNA, Messenger

1989
Vasoactive intestinal peptide control of renal adenylate cyclase: in vitro studies of canine renal membranes and cultured canine renal epithelial (MDCK) cells.
    Quarterly journal of experimental physiology (Cambridge, England), 1989, Volume: 74, Issue:3

    Topics: Adenylyl Cyclases; Animals; Cell Line; Colforsin; Cyclic AMP; Dogs; Epithelial Cells; Epithelium; Glucagon; Kidney; Vasoactive Intestinal Peptide

1989
Multiple defects occur in the guanine nucleotide regulatory protein system in liver plasma membranes of obese (fa/fa) but not lean (Fa/Fa) Zucker rats: loss of functional Gi and abnormal Gs function.
    Cellular signalling, 1989, Volume: 1, Issue:1

    Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Blotting, Western; Cell Membrane; Cholera Toxin; Colforsin; Diabetes Mellitus, Experimental; Glucagon; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Insulin Resistance; Liver; Male; NAD; Obesity; Pertussis Toxin; Phosphorus Radioisotopes; Rats; Rats, Inbred Strains; Rats, Zucker; Receptors, Gastrointestinal Hormone; Receptors, Glucagon; Virulence Factors, Bordetella

1989
Forskolin, an activator of adenylate cyclase, stimulates pancreatic insulin, glucagon, and somatostatin release in the dog: studies in vitro.
    Endocrinology, 1985, Volume: 116, Issue:6

    Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Atropine; Calcium; Colforsin; Diterpenes; Dogs; Dose-Response Relationship, Drug; Enzyme Activation; Glucagon; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Pancreas; Phentolamine; Propranolol; Somatostatin

1985
Age-dependent effects of phorbol ester on adenylate cyclase stimulation by glucagon in liver of female rats.
    Biomedica biochimica acta, 1989, Volume: 48, Issue:4

    Topics: Adenylyl Cyclases; Animals; Colforsin; Female; Fetus; Glucagon; Guanylyl Imidodiphosphate; In Vitro Techniques; Isoproterenol; Kinetics; Liver; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate

1989
Emergence of beta adrenergic-responsive hepatic glycogenolysis in male rats during post-maturational aging.
    Biochemical and biophysical research communications, 1987, Sep-15, Volume: 147, Issue:2

    Topics: Adenylyl Cyclases; Aging; Animals; Colforsin; Enzyme Activation; Epinephrine; Glucagon; Glucose; Glycogen; Isoproterenol; Liver; Male; Propranolol; Rats; Rats, Inbred F344; Receptors, Adrenergic, beta

1987
Benzyl alcohol increases membrane fluidity and modulates cyclic AMP synthesis in intact renal epithelial cells.
    Biochimica et biophysica acta, 1987, Oct-02, Volume: 903, Issue:2

    Topics: Animals; Benzyl Alcohol; Benzyl Alcohols; Benzyl Compounds; Cell Line; Colforsin; Cyclic AMP; Dinoprostone; Diphenylhexatriene; Epithelium; Fluorescence Polarization; Fluorescent Dyes; Glucagon; GTP-Binding Proteins; Indomethacin; Kidney; Manganese; Membrane Fluidity; Prostaglandins E; Vasopressins

1987
Arginine vasopressin increases cellular free calcium concentration and adenosine 3',5'-monophosphate production in rat renal papillary collecting tubule cells in culture.
    Endocrinology, 1988, Volume: 123, Issue:3

    Topics: Animals; Arginine Vasopressin; Bucladesine; Calcium; Calcium Radioisotopes; Cells, Cultured; Colforsin; Cyclic AMP; Egtazic Acid; Glucagon; Kidney Tubules; Kidney Tubules, Collecting; Kinetics; Male; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate

1988
AVP-sensitive cAMP production is dependent on calmodulin in both MTAL and MCT.
    The American journal of physiology, 1988, Volume: 255, Issue:5 Pt 2

    Topics: Adenylyl Cyclases; Animals; Arginine Vasopressin; Calmodulin; Colforsin; Cyclic AMP; Enzyme Activation; Glucagon; Kidney Tubules; Kidney Tubules, Collecting; Loop of Henle; Mice; Sulfonamides; Trifluoperazine

1988
Homologous and heterologous beta-adrenergic desensitization in hepatocytes. Additivity and effect of pertussis toxin.
    Biochimica et biophysica acta, 1988, Dec-09, Volume: 972, Issue:3

    Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Drug Interactions; Enzyme Activation; Female; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hypothyroidism; Isoproterenol; Liver; Pertussis Toxin; Propranolol; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Tetradecanoylphorbol Acetate; Urea; Vasopressins; Virulence Factors, Bordetella

1988
In vivo desensitization of glycogenolysis to Ca2+-mobilizing hormones in rat liver cells.
    The Journal of clinical investigation, 1988, Volume: 82, Issue:6

    Topics: Adrenal Gland Neoplasms; Angiotensin II; Animals; Arginine Vasopressin; Bucladesine; Calcimycin; Calcium; Colforsin; Glucagon; Hormones; Liver Glycogen; Male; Norepinephrine; Phenoxybenzamine; Phenylephrine; Pheochromocytoma; Phosphorylases; Prazosin; Rats; Receptors, Adrenergic, alpha; Second Messenger Systems

1988
Inhibitory effect of neurohypophysial peptides on cyclic AMP accumulation by isolated hepatocytes of the trout.
    The Journal of endocrinology, 1988, Volume: 119, Issue:3

    Topics: Animals; Colforsin; Cyclic AMP; Depression, Chemical; Dose-Response Relationship, Drug; Glucagon; Humans; In Vitro Techniques; Liver; Pituitary Hormones, Posterior; Salmonidae; Time Factors; Trout

1988
Mode of adrenergic and peptidergic inhibition of ion transport in flounder gill.
    The American journal of physiology, 1986, Volume: 251, Issue:6 Pt 2

    Topics: Animals; Biological Transport; Colforsin; Cyclic AMP; Epinephrine; Epithelium; Flounder; Gills; Glucagon; Ions; Membrane Potentials; Somatostatin; Thionucleotides

1986
Distribution of somatostatin receptors in RINm5F insulinoma cells.
    Endocrinology, 1988, Volume: 122, Issue:3

    Topics: Adenoma, Islet Cell; Animals; Cell Fractionation; Cell Membrane; Colforsin; Cytoplasmic Granules; Cytosol; Glucagon; Glyceraldehyde; Insulin; Insulin Secretion; Insulinoma; Iodine Radioisotopes; Kinetics; Leucine; Microsomes; Pancreatic Neoplasms; Rats; Receptors, Neurotransmitter; Receptors, Somatostatin; Somatostatin; Tumor Cells, Cultured

1988
Role of a guanine nucleotide-binding regulatory protein in the hydrolysis of hepatocyte phosphatidylinositol 4,5-bisphosphate by calcium-mobilizing hormones and the control of cell calcium. Studies utilizing aluminum fluoride.
    The Journal of biological chemistry, 1985, Nov-25, Volume: 260, Issue:27

    Topics: Aluminum; Aluminum Compounds; Animals; Calcium; Colforsin; Cyclic AMP; Enzyme Activation; Fluorides; Glucagon; Glycogen Synthase; GTP-Binding Proteins; Hydrolysis; In Vitro Techniques; Kinetics; Liver; Male; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Phosphorylase a; Rats; Sodium Fluoride; Vasopressins

1985
Effects of delta 9-tetrahydrocannabinol on glucagon receptor coupling to adenylate cyclase in rat liver plasma membranes.
    Biochemical pharmacology, 1986, Aug-15, Volume: 35, Issue:16

    Topics: Adenylyl Cyclases; Animals; Cannabinoids; Cell Membrane; Colforsin; Dronabinol; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Liver; Male; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Glucagon; Sodium Fluoride

1986
A dose-response study of forskolin, stimulatory hormone, and guanosine triphosphate analog on adenylate cyclase from several sources.
    Archives of biochemistry and biophysics, 1986, Nov-15, Volume: 251, Issue:1

    Topics: Adenylyl Cyclases; Adipose Tissue; Adrenocorticotropic Hormone; Animals; Cell Membrane; Colforsin; Drug Synergism; Enzyme Activation; Epinephrine; Erythrocyte Membrane; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hormones; Liver; Rabbits; Rats; Solubility

1986
4 beta-Phorbol 12-myristate 13-acetate attenuates the glucagon-induced increase in cytoplasmic free Ca2+ concentration in isolated rat hepatocytes.
    The Biochemical journal, 1986, Sep-15, Volume: 238, Issue:3

    Topics: Aminoquinolines; Animals; Bucladesine; Calcium; Colforsin; Fluorescent Dyes; Glucagon; In Vitro Techniques; Liver; Male; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate

1986
Abnormal regulation of insulin secretion in the genetically obese (ob/ob) mouse.
    The Biochemical journal, 1986, Sep-15, Volume: 238, Issue:3

    Topics: Animals; Calcium; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Glucagon; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Species Specificity

1986
High Ca2+ inhibits peptide hormone-dependent cAMP production specifically in thick ascending limbs of Henle.
    Mineral and electrolyte metabolism, 1986, Volume: 12, Issue:5-6

    Topics: Animals; Arginine Vasopressin; Calcium; Colforsin; Cyclic AMP; Glucagon; Kidney Tubules; Kidney Tubules, Collecting; Loop of Henle; Male; Mice

1986
Epidermal growth factor mimics insulin effects in rat hepatocytes.
    The Biochemical journal, 1986, Nov-01, Volume: 239, Issue:3

    Topics: Animals; Arginine Vasopressin; Calcium; Colforsin; Cyclic AMP; Enzyme Activation; Epidermal Growth Factor; Glucagon; Glycogen Synthase; Insulin; Liver; Male; Phenylephrine; Rats

1986
Beta-adrenergic receptors, glucagon receptors, and their relationship to adenylate cyclase in rat liver during aging.
    Endocrinology, 1987, Volume: 120, Issue:4

    Topics: Adenylyl Cyclases; Aging; Animals; Colforsin; Enzyme Activation; Glucagon; Guanine Nucleotides; Guanylyl Imidodiphosphate; Isoproterenol; Liver; Male; Pindolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Receptors, Gastrointestinal Hormone; Receptors, Glucagon; Sodium Fluoride

1987
Role of second messengers in the regulation of glucagon secretion from isolated rat islets of Langerhans.
    Molecular and cellular endocrinology, 1987, Volume: 50, Issue:1-2

    Topics: Animals; Arginine; Calcimycin; Calcium; Colforsin; Cyclic AMP; Diglycerides; Drug Interactions; Glucagon; Glycerides; Islets of Langerhans; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Trifluoperazine

1987
Development of physiological responsiveness to glucagon during embryogenesis of avian heart.
    Developmental biology, 1987, Volume: 122, Issue:1

    Topics: Adenylyl Cyclases; Animals; Cells, Cultured; Chick Embryo; Cholera Toxin; Colforsin; Glucagon; GTP-Binding Proteins; Heart; Myocardial Contraction; Receptors, Gastrointestinal Hormone; Receptors, Glucagon; Stimulation, Chemical; Time Factors

1987
Protein kinase C activators and bradykinin selectively inhibit vasopressin-stimulated cAMP synthesis in MDCK cells.
    Biochimica et biophysica acta, 1987, Jul-29, Volume: 929, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Bradykinin; Cell Line; Colforsin; Cyclic AMP; Diglycerides; Dinoprostone; Enzyme Activation; Glucagon; Isoquinolines; Piperazines; Prostaglandins E; Protein Kinase C; Tetradecanoylphorbol Acetate; Vasopressins

1987
Alterations in the myocardial beta-adrenoceptor system of streptozotocin-diabetic rats.
    European journal of pharmacology, 1987, Apr-29, Volume: 136, Issue:3

    Topics: Animals; Blood Glucose; Body Weight; Calcium; Catecholamines; Colforsin; Diabetes Mellitus, Experimental; Electric Stimulation; Glucagon; Glycated Hemoglobin; In Vitro Techniques; Isoproterenol; Male; Methoxamine; Myocardial Contraction; Myocardium; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta

1987
Nutrient and hormonal regulation of the threshold of glucose-stimulated insulin secretion in isolated rat pancreases.
    Endocrinology, 1988, Volume: 123, Issue:3

    Topics: Animals; Carbachol; Colforsin; Fasting; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucose; Growth Hormone; Hormones; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Perfusion; Prolactin; Rats; Reference Values; Sincalide

1988
cAMP-dependent protein phosphorylation of membrane proteins in the parotid gland, platelets and liver. Comparison of a 22-kDa phosphoprotein from rat parotid microsomes (protein III) with phosphoproteins of similar molecular size from platelet and liver m
    European journal of biochemistry, 1988, Jul-01, Volume: 174, Issue:4

    Topics: Animals; Blood Platelets; Colforsin; Electrophoresis, Polyacrylamide Gel; Glucagon; Liver; Male; Membrane Proteins; Microsomes, Liver; Molecular Weight; Parotid Gland; Phosphorylation; Protein Kinases; Rats; Rats, Inbred Strains

1988
Altered responsiveness of adenylate cyclase to adenosine and other agents in the myocardial sarcolemma and aorta of spontaneously-hypertensive rats.
    Biochemical pharmacology, 1988, Aug-01, Volume: 37, Issue:15

    Topics: Adenosine; Adenylyl Cyclases; Animals; Aorta; Colforsin; Epinephrine; Female; Glucagon; Hypertension; In Vitro Techniques; Myocardium; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sarcolemma

1988
Restoration of the A cell response to glucose in isolated rat islets of Langerhans.
    Molecular and cellular endocrinology, 1986, Volume: 48, Issue:2-3

    Topics: Animals; Arginine; Colforsin; Glucagon; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate

1986
Loss of adenylate cyclase activity in preneoplastic and neoplastic lesions induced in rat liver by N-nitrosomorpholine.
    Carcinogenesis, 1986, Volume: 7, Issue:4

    Topics: Adenylyl Cyclase Inhibitors; Animals; Cholera Toxin; Colforsin; Glucagon; Glucosephosphate Dehydrogenase; Liver; Liver Neoplasms; Male; Microscopy, Electron; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred Strains

1986
Alterations of rat cardiac adenylate cyclase activity with age.
    European journal of pharmacology, 1986, Jul-15, Volume: 126, Issue:1-2

    Topics: Adenylyl Cyclases; Aging; Animals; Colforsin; Glucagon; Guanylyl Imidodiphosphate; Isoproterenol; Male; Myocardium; Rats; Rats, Inbred Strains; Secretin; Sodium Fluoride

1986
Preparation of rat liver plasma membrane with respect to glucagon-sensitive adenylate cyclase.
    Analytical biochemistry, 1986, Aug-15, Volume: 157, Issue:1

    Topics: Adenylyl Cyclases; Animals; Cell Fractionation; Cell Membrane; Colforsin; Enzyme Activation; Glucagon; Guanylyl Imidodiphosphate; Liver; Male; Rats; Rats, Inbred Strains

1986
Forms of adenylate cyclase, activation and/or potentiation by forskolin.
    Archives of biochemistry and biophysics, 1986, Nov-15, Volume: 251, Issue:1

    Topics: Adenylyl Cyclases; Adipose Tissue; Animals; Binding Sites; Cell Membrane; Chromatography, Affinity; Colforsin; Drug Synergism; Enzyme Activation; Epinephrine; Glucagon; Guanylyl Imidodiphosphate; Liver; Rats

1986
cAMP-dependent protein kinase and lipolysis in rat adipocytes. II. Definition of steady-state relationship with lipolytic and antilipolytic modulators.
    The Journal of biological chemistry, 1985, Dec-05, Volume: 260, Issue:28

    Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adipose Tissue; Animals; Colforsin; Cosyntropin; Deoxyadenosines; Dideoxyadenosine; Enzyme Activation; Glucagon; Glycerol; Isoproterenol; Kinetics; Lipolysis; Male; Phenylisopropyladenosine; Protein Kinases; Rats; Rats, Inbred Strains; Time Factors

1985
Streptozotocin-induced diabetes and hormone sensitivity of adenylate cyclase in rat myocardial sarcolemma, aorta and liver.
    Biochemical pharmacology, 1985, Jun-01, Volume: 34, Issue:11

    Topics: Adenylyl Cyclases; Animals; Aorta; Catecholamines; Colforsin; Corpus Striatum; Diabetes Mellitus, Experimental; Diterpenes; Glucagon; Guanosine Triphosphate; Hormones; Liver; Male; Myocardium; Rats; Rats, Inbred Strains; Sarcolemma

1985
Inhibitory effects of pentacaine and some related local anaesthetics on rat hepatic adenylate cyclase.
    General physiology and biophysics, 1985, Volume: 4, Issue:5

    Topics: Adenylyl Cyclase Inhibitors; Anesthetics, Local; Animals; Carbamates; Colforsin; Glucagon; Glucosides; Guanylyl Imidodiphosphate; Liver; Piperidines; Rats; Structure-Activity Relationship

1985
Glucagon and forskolin have dual effects upon islet cell electrical activity.
    Life sciences, 1984, Aug-06, Volume: 35, Issue:6

    Topics: Action Potentials; Animals; Calcium; Colforsin; Cyclic AMP; Diterpenes; Drug Synergism; Electrophysiology; Female; Glucagon; Glucose; Islets of Langerhans; Mice; Time Factors

1984
Metabolic effects and cyclic AMP levels produced by glucagon, (1-N alpha-Trinitrophenylhistidine,12-homoarginine)glucagon and forskolin in isolated rat hepatocytes.
    Biochimica et biophysica acta, 1984, Aug-17, Volume: 804, Issue:4

    Topics: Animals; Calcium; Colforsin; Cyclic AMP; Diterpenes; Glucagon; Gluconeogenesis; Glycogen; Liver; Rats; Urea

1984
Phosphorylation of histones and non-histone nuclear proteins in liver cells stimulated by glucagon and cyclic AMP.
    FEBS letters, 1984, Dec-03, Volume: 178, Issue:1

    Topics: Animals; Cell-Free System; Chromosomal Proteins, Non-Histone; Colforsin; Cyclic AMP; Diterpenes; Electrophoresis, Polyacrylamide Gel; Glucagon; Histones; Liver; Molecular Weight; Phosphorylation; Rats

1984
Calmodulin and cyclic AMP. Possible different sites of action of these two regulatory agents in exocytotic hormone release.
    Diabetes, 1984, Volume: 33, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Calmodulin; Colforsin; Cyclic AMP; Diterpenes; Exocytosis; Glucagon; Glucose; Hormones; Insulin; Insulin Secretion; Islets of Langerhans; Male; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Somatostatin; Somatostatin

1984
Forskolin as a novel lipolytic agent.
    Biochemical and biophysical research communications, 1982, Jul-16, Volume: 107, Issue:1

    Topics: Adenylyl Cyclases; Adipose Tissue; Adrenocorticotropic Hormone; Animals; Cell Membrane; Colforsin; Cyclic AMP; Diterpenes; Drug Synergism; Epinephrine; Fatty Acids, Nonesterified; Glucagon; Guanylyl Imidodiphosphate; In Vitro Techniques; Kinetics; Lipolysis; Male; Rats; Sodium Fluoride

1982
Studies on the mechanism of inhibition of hepatic cAMP accumulation by vasopressin.
    FEBS letters, 1983, Nov-14, Volume: 163, Issue:2

    Topics: Adenylyl Cyclases; Animals; Calcium; Calmodulin; Chlorpromazine; Colforsin; Cyclic AMP; Diterpenes; Dose-Response Relationship, Drug; Enzyme Activation; Glucagon; In Vitro Techniques; Liver; Male; Rats; Rats, Inbred Strains; Trifluoperazine; Vasopressins

1983
[Forskolin, cyclic AMP and hormone regulation].
    Nihon Naibunpi Gakkai zasshi, 1983, Nov-20, Volume: 59, Issue:11

    Topics: Adrenal Glands; Animals; Cell Membrane Permeability; Colforsin; Corticosterone; Cyclic AMP; Deoxyglucose; Diabetes Mellitus, Experimental; Diterpenes; Glucagon; In Vitro Techniques; Liver; Phosphofructokinase-1; Phosphotransferases; Rats

1983
Mechanism of heterologous desensitization of the adenylate cyclase system by glucagon in primary cultures of adult rat hepatocytes.
    The Journal of biological chemistry, 1984, Jun-25, Volume: 259, Issue:12

    Topics: Adenylyl Cyclases; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Diterpenes; Glucagon; Guanylyl Imidodiphosphate; Iodocyanopindolol; Isoproterenol; Liver; Male; Pindolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Sodium Fluoride

1984
Effects of VIP and forskolin on alanine metabolism in isolated hepatocytes.
    FEBS letters, 1984, Aug-06, Volume: 173, Issue:2

    Topics: Alanine; Animals; Colforsin; Diterpenes; Fasting; Glucagon; Gluconeogenesis; In Vitro Techniques; Kinetics; Liver; Male; Rats; Rats, Inbred Strains; Urea; Vasoactive Intestinal Peptide

1984
Alteration with dietary state of the activity and zonal distribution of adenylate cyclase stimulated by glucagon, fluoride and forskolin in microdissected rat liver tissue.
    European journal of biochemistry, 1984, Dec-17, Volume: 145, Issue:3

    Topics: Adenylyl Cyclases; Animals; Colforsin; Diet; Dissection; Diterpenes; Fasting; Fluorides; Glucagon; Histocytochemistry; Liver; Male; Rats; Rats, Inbred Strains

1984
Forskolin regulation of liver membrane adenylyl cyclase.
    European journal of biochemistry, 1983, Oct-17, Volume: 136, Issue:1

    Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Cell Membrane; Chemical Phenomena; Chemistry; Colforsin; Diterpenes; Enzyme Activation; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Liver; Rats; Sodium Fluoride

1983
Expression of alpha 2-receptor-mediated responses by insulin in primary culture of rat hepatocytes.
    Japanese journal of pharmacology, 1995, Volume: 68, Issue:1

    Topics: Animals; Cells, Cultured; Clonidine; Colforsin; Cyclic AMP; Cycloheximide; Drug Interactions; Glucagon; Glucose; Insulin; Liver; Male; Oxymetazoline; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Time Factors

1995
Amylin (islet amyloid polypeptide) inhibition of insulin release in the perfused rat pancreas: implication of the adenylate cyclase/cAMP system.
    Regulatory peptides, 1994, Feb-24, Volume: 50, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Amyloid; Animals; Colforsin; Cyclic AMP; Gastric Inhibitory Polypeptide; Glucagon; Insulin; Insulin Secretion; Islet Amyloid Polypeptide; Islets of Langerhans; Male; Perfusion; Rats; Rats, Wistar

1994
Regulation of glucagon and glucagon-like peptide-1 receptor messenger ribonucleic acid expression in cultured rat pancreatic islets by glucose, cyclic adenosine 3',5'-monophosphate, and glucocorticoids.
    Endocrinology, 1995, Volume: 136, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Dexamethasone; Dose-Response Relationship, Drug; Gene Expression Regulation; Glucagon; Glucagon-Like Peptide 1; Glucose; Islets of Langerhans; Peptide Fragments; Protein Precursors; Rats; Rats, Wistar; Receptors, Glucagon; Ribonucleases; RNA, Messenger

1995
Activation of proglucagon gene transcription by protein kinase-A in a novel mouse enteroendocrine cell line.
    Molecular endocrinology (Baltimore, Md.), 1994, Volume: 8, Issue:12

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Antigens, Polyomavirus Transforming; Bucladesine; Cholera Toxin; Colforsin; Cyclic AMP-Dependent Protein Kinases; Gene Expression; Glucagon; Glucagon-Like Peptide 1; Intestinal Neoplasms; Mice; Mice, Nude; Mice, Transgenic; Microscopy, Electron; Neoplasm Transplantation; Peptide Fragments; Proglucagon; Protein Precursors; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured

1994
VIP inhibits basal and histamine-stimulated proliferation of human airway smooth muscle cells.
    The American journal of physiology, 1995, Volume: 268, Issue:6 Pt 1

    Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Carbazoles; Cell Cycle; Cell Division; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DNA; Dose-Response Relationship, Drug; Glucagon; Histamine; Histamine Antagonists; Humans; Indoles; Kinetics; Muscle, Smooth; Pyrroles; Thymidine; Trachea; Vasoactive Intestinal Peptide

1995
Hormone stimulation of type III adenylyl cyclase induces Ca2+ oscillations in HEK-293 cells.
    The Journal of biological chemistry, 1995, Oct-13, Volume: 270, Issue:41

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Calcium; Calcium Channels; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Cell Line; Colforsin; Cyclic AMP; Enzyme Activation; Enzyme Inhibitors; Glucagon; Humans; Inositol 1,4,5-Trisphosphate Receptors; Isoproterenol; Isoquinolines; Kidney; Kinetics; Models, Biological; Oscillometry; Phosphatidylinositols; Piperazines; Receptors, Cytoplasmic and Nuclear; Receptors, Glucagon; Signal Transduction; Time Factors

1995
Effect of glucagon on intracellular pH regulation in isolated rat hepatocyte couplets.
    The Journal of clinical investigation, 1995, Volume: 96, Issue:2

    Topics: Animals; Antiporters; Bicarbonates; Bile; Bucladesine; Cells, Cultured; Chloride-Bicarbonate Antiporters; Chlorides; Cholagogues and Choleretics; Colchicine; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Glucagon; Hydrogen-Ion Concentration; Intracellular Fluid; Isoquinolines; Liver; Male; Nitrobenzoates; Rats; Rats, Wistar; Sodium; Sodium-Hydrogen Exchangers; Sulfonamides; Tetradecanoylphorbol Acetate; Thionucleotides

1995
Multiple cis-acting domains mediate basal and adenosine 3',5'-monophosphate-dependent glucagon gene transcription in a mouse neuroendocrine cell line.
    Endocrinology, 1993, Volume: 132, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Base Sequence; Cell Line; Chloramphenicol O-Acetyltransferase; Colforsin; Cyclic AMP; Glucagon; Intestinal Neoplasms; Mice; Mice, Transgenic; Neurosecretory Systems; Recombinant Fusion Proteins; RNA, Messenger; Transcription, Genetic; Transfection; Tumor Cells, Cultured

1993
Amylin alters the biological action of the incretin hormone GLP-1(7-36)amide.
    Life sciences, 1993, Volume: 53, Issue:17

    Topics: Adenylyl Cyclases; Amyloid; Animals; Cell Line; Colforsin; Cyclic AMP; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Intolerance; Insulinoma; Islet Amyloid Polypeptide; Islets of Langerhans; Models, Biological; Peptide Fragments; Peptides; Rats; Substance P

1993
Increasing cAMP attenuates activation of mitogen-activated protein kinase.
    Proceedings of the National Academy of Sciences of the United States of America, 1993, Nov-01, Volume: 90, Issue:21

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adipocytes; Animals; Bucladesine; Calcium-Calmodulin-Dependent Protein Kinases; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Epididymis; Glucagon; Isoenzymes; Isoproterenol; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphoproteins; Phosphotyrosine; Rats; Rats, Sprague-Dawley; Thionucleotides; Tyrosine

1993
cAMP and protein synthesis in isolated adult rat heart preparations.
    The American journal of physiology, 1993, Volume: 265, Issue:5 Pt 1

    Topics: 1-Methyl-3-isobutylxanthine; Adenine Nucleotides; Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Energy Metabolism; Epinephrine; Glucagon; Heart; Hypertension; In Vitro Techniques; Isoproterenol; Kinetics; Male; Myocardium; Perfusion; Phenylephrine; Phosphocreatine; Prazosin; Propranolol; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; Yohimbine

1993
cAMP-associated inhibition of phenobarbital-inducible cytochrome P450 gene expression in primary rat hepatocyte cultures.
    The Journal of biological chemistry, 1995, May-26, Volume: 270, Issue:21

    Topics: Albumins; Animals; Aryl Hydrocarbon Hydroxylases; Base Sequence; Benzoflavones; beta-Naphthoflavone; Bucladesine; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dexamethasone; Dichlororibofuranosylbenzimidazole; Dose-Response Relationship, Drug; Enzyme Induction; Gene Expression Regulation, Enzymologic; Glucagon; Liver; Mixed Function Oxygenases; Molecular Sequence Data; Phenobarbital; Phosphodiesterase Inhibitors; Rats; Stereoisomerism; Steroid Hydroxylases; Thionucleotides; Transcriptional Activation

1995
Glucagon-like peptide I increases cytoplasmic calcium in insulin-secreting beta TC3-cells by enhancement of intracellular calcium mobilization.
    Diabetes, 1995, Volume: 44, Issue:7

    Topics: Animals; Calcium; Calcium Channels; Cell Line; Colforsin; Cyclic AMP; Cytoplasm; Dose-Response Relationship, Drug; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Inositol Phosphates; Insulin; Insulin Secretion; Insulinoma; Islets of Langerhans; Kinetics; Mice; Mice, Transgenic; Pancreatic Neoplasms; Peptide Fragments; Ryanodine; Time Factors; Tumor Cells, Cultured

1995
Catecholamine-induced cAMP response in streptozotocin-induced diabetic rat liver.
    The Tohoku journal of experimental medicine, 1994, Volume: 173, Issue:3

    Topics: Adipose Tissue; Animals; Colforsin; Cyclic AMP; Diabetes Mellitus, Experimental; Emaciation; Epinephrine; Glucagon; Glucose; Insulin; Isoproterenol; Lactates; Lactic Acid; Liver; Male; Oxymetazoline; Phenylephrine; Propranolol; Pyruvates; Pyruvic Acid; Rats; Receptors, Adrenergic, beta; Streptozocin

1994
Activity of cAMP-dependent protein kinase is reduced in protein-energy malnourished rats.
    The Journal of nutrition, 1995, Volume: 125, Issue:3

    Topics: Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Dietary Proteins; Glucagon; Glutathione; Guanine Nucleotides; Liver; Male; Manganese; Protein Kinases; Protein-Energy Malnutrition; Rats; Rats, Wistar; Receptors, Glucagon; Signal Transduction

1995
Interaction of glucagon-like peptide-I (7-37) and somatostatin-14 on signal transduction and proinsulin gene expression in beta TC-1 cells.
    Metabolism: clinical and experimental, 1994, Volume: 43, Issue:6

    Topics: Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Drug Interactions; Gene Expression; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Insulinoma; Mice; Pancreatic Neoplasms; Peptides; Proinsulin; Receptors, Cell Surface; Receptors, Glucagon; Signal Transduction; Somatostatin; Tumor Cells, Cultured

1994
G proteins in rat liver proliferation during cholestasis.
    Hepatology (Baltimore, Md.), 1994, Volume: 20, Issue:4 Pt 1

    Topics: Adenosine Diphosphate; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Bile Ducts; Cell Division; Cell Membrane; Cholera Toxin; Cholestasis; Colforsin; Glucagon; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Ligation; Liver; Male; Peptide Fragments; Pertussis Toxin; Rats; Rats, Wistar; Vasoactive Intestinal Peptide; Virulence Factors, Bordetella

1994
Anti-diabetic biguanides inhibit hormone-induced intracellular Ca2+ concentration oscillations in rat hepatocytes.
    The Biochemical journal, 1994, Dec-01, Volume: 304 ( Pt 2)

    Topics: Animals; Biguanides; Bucladesine; Calcium; Chlorides; Colforsin; Cyclic AMP; Glucagon; Inositol 1,4,5-Trisphosphate; Insulin; Liver; Male; Manganese Compounds; Metformin; Phenformin; Phenylephrine; Rats; Rats, Wistar; Second Messenger Systems

1994
Analysis of the adenylate cyclase signalling system, and alterations induced by culture with insulin, in a novel SV40-DNA-immortalized hepatocyte cell line (P9 cells).
    The Biochemical journal, 1994, Jun-15, Volume: 300 ( Pt 3)

    Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Alprostadil; Animals; Cell Line; Cell Transformation, Viral; Colforsin; Glucagon; GTP-Binding Proteins; Guanosine Triphosphate; Insulin; Liver; Male; Rats; Rats, Sprague-Dawley; Receptor, Insulin; Signal Transduction

1994
Multi-site phosphorylation of the inhibitory guanine nucleotide regulatory protein Gi-2 occurs in intact rat hepatocytes.
    The Biochemical journal, 1994, Aug-01, Volume: 301 ( Pt 3)

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amino Acid Sequence; Animals; Binding Sites; Colforsin; Glucagon; GTP-Binding Proteins; Immunosorbent Techniques; Isoelectric Point; Liver; Male; Molecular Sequence Data; Peptide Fragments; Phosphorylation; Phosphoserine; Rats; Rats, Sprague-Dawley; Serine Endopeptidases; Tetradecanoylphorbol Acetate; Trypsin; Vasopressins

1994
Stimulation of glucagon-like peptide-1 secretion by muscarinic agonist in a murine intestinal endocrine cell line.
    Endocrinology, 1994, Volume: 134, Issue:5

    Topics: Calcium; Carbachol; Cell Line; Colforsin; Cyclic AMP; Endocrine Glands; Glucagon; Glucagon-Like Peptide 1; Intestinal Mucosa; Intestines; Kinetics; Muscarinic Antagonists; N-Methylscopolamine; Parasympathomimetics; Peptide Fragments; Protein Precursors; Receptors, Muscarinic; Scopolamine Derivatives; Tetradecanoylphorbol Acetate

1994
[Hormonal regulation of carbohydrate metabolism in the liver in plague intoxication].
    Biokhimiia (Moscow, Russia), 1994, Volume: 59, Issue:3

    Topics: Adenylyl Cyclases; Animals; Bacterial Toxins; Blood Glucose; Carbohydrate Metabolism; Colforsin; Cyclic AMP; Enzyme Activation; Fluorides; Glucagon; Guanylyl Imidodiphosphate; Isoproterenol; Liver; Liver Glycogen; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Yersinia pestis

1994
Stimulation of rat parietal cell function by histamine and GLP-1-(7-36) amide is mediated by Gs alpha.
    The American journal of physiology, 1994, Volume: 266, Issue:5 Pt 1

    Topics: Adenosine Diphosphate; Adenylyl Cyclases; Aminopyrine; Animals; Cell Membrane; Cell Separation; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; GTP-Binding Proteins; Histamine; Kinetics; Molecular Weight; Parietal Cells, Gastric; Peptide Fragments; Rats; Rats, Wistar

1994
Modulators of the protein kinase C system influence biliary excretion of cationic drugs.
    Hepatology (Baltimore, Md.), 1993, Volume: 18, Issue:5

    Topics: Alkaloids; Animals; Bile; Biological Transport, Active; Carrier Proteins; Cations; Cell Membrane; Cells, Cultured; Colforsin; Cyclic AMP; Glucagon; In Vitro Techniques; Liver; Male; Perfusion; Protein Kinase C; Quaternary Ammonium Compounds; Rats; Rats, Wistar; Second Messenger Systems; Staurosporine; Tetradecanoylphorbol Acetate; Vasopressins

1993
Different modulatory effects of elevated cyclic AMP on cytosolic Ca2+ spikes induced by phenylephrine or vasopressin in single rat hepatocytes.
    The Biochemical journal, 1993, Apr-01, Volume: 291 ( Pt 1)

    Topics: Animals; Bucladesine; Calcium; Colforsin; Cyclic AMP; Cytosol; Glucagon; Liver; Male; Phenylephrine; Rats; Rats, Wistar; Vasopressins

1993
Adenylate cyclase activity in microdissected rat liver tissue: periportal to pericentral activity gradient.
    Hepatology (Baltimore, Md.), 1993, Volume: 18, Issue:1

    Topics: Adenylyl Cyclases; Angiotensin II; Animals; Chlorides; Cholera Toxin; Colforsin; Cyclic AMP; Glucagon; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Lithium; Lithium Chloride; Liver; Male; Rats; Rats, Sprague-Dawley; Sodium Fluoride

1993
Regulation of malic-enzyme-gene expression by cAMP and retinoic acid in differentiating brown adipocytes.
    European journal of biochemistry, 1993, Jul-15, Volume: 215, Issue:2

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adipose Tissue; Animals; Cell Differentiation; Cells, Cultured; Colforsin; Cyclic AMP; Gene Expression Regulation, Enzymologic; Glucagon; Insulin; Malate Dehydrogenase; Norepinephrine; Rats; RNA, Messenger; Tretinoin; Triiodothyronine

1993
Epidermal growth factor modulates the lipolytic action of catecholamines in rat adipocytes. Involvement of a Gi protein.
    The Journal of biological chemistry, 1993, Aug-15, Volume: 268, Issue:23

    Topics: Adenosine; Adenosine Deaminase; Adipose Tissue; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Epidermal Growth Factor; Glucagon; GTP-Binding Proteins; Isoproterenol; Lipolysis; Male; Rats; Rats, Wistar; Signal Transduction

1993
Neuropeptide Y expression and regulation in a differentiated rat insulin-secreting cell line.
    Endocrinology, 1993, Volume: 133, Issue:3

    Topics: Adenylyl Cyclases; Animals; Cell Differentiation; Clonidine; Colforsin; Cyclic AMP; Enzyme Activation; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation, Neoplastic; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Insulin; Insulin Secretion; Insulinoma; Neuropeptide Y; Pancreatic Neoplasms; Peptide Fragments; Protein Kinase C; Rats; Receptors, Neuropeptide Y; Tumor Cells, Cultured

1993
Long-term inhibitory effect of cAMP on beta-adrenoceptor acquisition and nonselective attenuation of adenylyl cyclase in hepatocytes.
    European journal of pharmacology, 1993, Jul-15, Volume: 246, Issue:2

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Down-Regulation; Glucagon; Iodocyanopindolol; Isoproterenol; Liver; Male; Pindolol; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Thionucleotides

1993
Chronic exposure of rat fat cells to insulin enhances lipolysis and activation of partially purified hormone-sensitive lipase.
    Diabetes, 1993, Volume: 42, Issue:10

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adipose Tissue; Adrenocorticotropic Hormone; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Activation; Glucagon; Growth Hormone; Imidazoles; Insulin; Isoproterenol; Lipase; Lipolysis; Male; Norepinephrine; Phosphorylation; Rats; Rats, Sprague-Dawley; Thyrotropin

1993
A recombinant human calcitonin receptor functions as an extracellular calcium sensor.
    The Journal of biological chemistry, 1993, Sep-25, Volume: 268, Issue:27

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcitonin; Calcium; Cell Line; Cell Membrane; Cloning, Molecular; Colforsin; Cricetinae; Cyclic AMP; Cytosol; Glucagon; Humans; Kidney; Kinetics; Receptors, Calcitonin; Receptors, Cell Surface; Recombinant Proteins; Time Factors; Transfection

1993
Inhibition of protein kinase A-induced glucagon synthesis and secretion by glucose.
    Metabolism: clinical and experimental, 1996, Volume: 45, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Citrates; Citric Acid; Colforsin; Cyclic AMP-Dependent Protein Kinases; Glucagon; Glucose; Male; Rats; Streptozocin

1996
Glucagon induces a rapid and sustained phosphorylation of the human glucagon receptor in Chinese hamster ovary cells.
    Biochemical and biophysical research communications, 1996, Mar-27, Volume: 220, Issue:3

    Topics: Amino Acid Sequence; Animals; Antibodies; CHO Cells; Colforsin; Cricetinae; Cyclic AMP-Dependent Protein Kinases; Glucagon; Humans; Kinetics; Molecular Sequence Data; Peptide Fragments; Phosphates; Phosphoproteins; Phosphorylation; Phosphoserine; Protein Kinase C; Receptors, Glucagon; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transfection

1996
Role of cAMP in the regulation of hepatocytic autophagy.
    European journal of biochemistry, 1996, Feb-15, Volume: 236, Issue:1

    Topics: Animals; Autophagy; Bucladesine; Cell Survival; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glucagon; Liver; Male; Protein Kinase Inhibitors; Proteins; Rats; Rats, Wistar

1996
Glucagon-like peptide-1(7-36)amide enhances insulin-stimulated glucose uptake and decreases intracellular cAMP content in isolated rat adipocytes.
    Biochimica et biophysica acta, 1996, Jun-13, Volume: 1312, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Adipocytes; Animals; Colforsin; Cyclic AMP; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Glucose; Insulin; Male; Peptide Fragments; Peptides; Phosphodiesterase Inhibitors; Rats

1996
Impaired cyclic AMP response to stimuli in glucose-desensitized rat pancreatic islets.
    Molecular and cellular endocrinology, 1995, Aug-30, Volume: 113, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Drug Synergism; Drug Tolerance; Glucagon; Glucagon-Like Peptide 1; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Male; Peptide Fragments; Protein Precursors; Rats; Rats, Sprague-Dawley

1995
The signal transduction of the glucagon-like peptide 1 receptor: fishing beyond the protein kinase level.
    Acta physiologica Scandinavica, 1996, Volume: 157, Issue:3

    Topics: Colforsin; Electrophoresis, Gel, Two-Dimensional; Glucagon; Glucagon-Like Peptide 1; Insulinoma; Isoelectric Focusing; Molecular Weight; Peptide Fragments; Phosphoproteins; Phosphorylation; Protein Kinases; Protein Precursors; Receptors, Glucagon; Signal Transduction; Tumor Cells, Cultured

1996
Effect of endurance physical training on rat liver adenylyl cyclase system.
    Cellular signalling, 1996, Volume: 8, Issue:4

    Topics: Adaptation, Physiological; Adenylyl Cyclases; Adrenergic beta-Antagonists; Animals; Colforsin; Enzyme Activation; Fluorides; Glucagon; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Isoproterenol; Liver; Male; Manganese; Physical Conditioning, Animal; Physical Endurance; Pindolol; Random Allocation; Rats; Rats, Wistar; Receptors, Adrenergic, beta

1996
Ligand-induced regulation of glucagon-like peptide-I receptor function and expression in insulin-secreting beta cells.
    Pancreas, 1996, Volume: 13, Issue:3

    Topics: Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Enzyme Activation; Gene Expression; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Guanosine 5'-O-(3-Thiotriphosphate); Insulin; Insulin Secretion; Insulinoma; Islets of Langerhans; Pancreatic Neoplasms; Peptide Fragments; Protein Precursors; Protein Synthesis Inhibitors; Rats; Receptors, Glucagon; RNA, Messenger; Tumor Cells, Cultured

1996
Stimulation of microsomal cholesterol ester hydrolase by glucagon, cyclic AMP analogues, and vasopressin in isolated rat hepatocytes.
    Lipids, 1996, Volume: 31, Issue:3

    Topics: Animals; Bucladesine; Cholesterol Esters; Colforsin; Cyclic AMP; Diglycerides; Glucagon; Microsomes, Liver; Particle Size; Prazosin; Rats; Sterol Esterase; Thionucleotides; Vasopressins

1996
Transcriptional regulation of apolipoprotein E expression by cyclic AMP.
    FEBS letters, 1996, Nov-18, Volume: 397, Issue:2-3

    Topics: Apolipoproteins E; Bucladesine; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Gene Expression Regulation; Glucagon; Humans; Promoter Regions, Genetic; RNA, Messenger; Transfection; Tumor Cells, Cultured

1996
Effects of age on beta adrenergic subtype activation of adenylyl cyclase in brown adipose tissue.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1996, Volume: 213, Issue:3

    Topics: Adenylyl Cyclases; Adipose Tissue, Brown; Adrenergic beta-Agonists; Age Factors; Animals; Colforsin; Dose-Response Relationship, Drug; Enzyme Activation; Ethanolamines; Gene Expression; Glucagon; Isoproterenol; Kinetics; Male; Rats; Rats, Inbred F344; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-3; Regression Analysis; RNA, Messenger; Sodium Fluoride

1996
Effect of PACAP, VIP, glucagon, and GLP1 on cAMP production and insulin release of HIT-T15 cells is passage dependent.
    Annals of the New York Academy of Sciences, 1996, Dec-26, Volume: 805

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Line; Cell Line, Transformed; Colforsin; Cricetinae; Cyclic AMP; Glucagon; Glucagon-Like Peptide 1; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Neuropeptides; Neurotransmitter Agents; Peptide Fragments; Pituitary Adenylate Cyclase-Activating Polypeptide; Protein Precursors; Swine; Vasoactive Intestinal Peptide

1996
Protein kinase A-dependent stimulation of exocytosis in mouse pancreatic beta-cells by glucose-dependent insulinotropic polypeptide.
    Diabetes, 1997, Volume: 46, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Cell Membrane; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Electric Conductivity; Enzyme Inhibitors; Exocytosis; Gastric Inhibitory Polypeptide; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Islets of Langerhans; Membrane Potentials; Mice; Mice, Inbred Strains; Peptide Fragments; Phosphodiesterase Inhibitors; Tetradecanoylphorbol Acetate; Thionucleotides

1997
cAMP-mediated c-fos expression in pressure-overloaded acceleration of protein synthesis in adult rat heart.
    Cardiovascular research, 1997, Volume: 33, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Blotting, Northern; Cardiomegaly; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Gene Expression; Genes, fos; Glucagon; Isoquinolines; Male; Perfusion; Phosphodiesterase Inhibitors; Pressure; Protein Biosynthesis; Protein Kinase C; Rats; Rats, Sprague-Dawley; Sulfonamides

1997
Ontogeny of regulatory mechanisms for beta-adrenoceptor control of rat cardiac adenylyl cyclase: targeting of G-proteins and the cyclase catalytic subunit.
    Journal of molecular and cellular cardiology, 1997, Volume: 29, Issue:2

    Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Age Factors; Animals; Animals, Newborn; Body Weight; Carbachol; Cell Membrane; Colforsin; Drug Hypersensitivity; Female; Glucagon; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; GTP-Binding Proteins; Guanosine Triphosphate; Heart; Isoproterenol; Male; Manganese; Membrane Proteins; Muscarinic Agonists; Myocardium; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Time Factors

1997
Mechanism of the impairment of the glucagon-stimulated phosphoenolpyruvate carboxykinase gene expression by interleukin-6 in rat hepatocytes: inhibition of the increase in cyclic 3',5' adenosine monophosphate and the downstream cyclic 3',5' adenosine mono
    Hepatology (Baltimore, Md.), 1997, Volume: 26, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Gene Expression Regulation, Enzymologic; Genes, Reporter; Glucagon; Interleukin-6; Liver; Male; Pertussis Toxin; Phosphoenolpyruvate Carboxykinase (GTP); Rats; Rats, Wistar; RNA, Messenger; Time Factors; Transfection; Virulence Factors, Bordetella

1997
Modulation of gliquidone action by forskolin in the pancreas of normal and GK rats.
    The American journal of physiology, 1997, Volume: 273, Issue:1 Pt 1

    Topics: Animals; Blood Glucose; Colforsin; Diabetes Mellitus, Type 2; Glucagon; Glucose; Hypoglycemic Agents; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Perfusion; Rats; Rats, Inbred Strains; Rats, Wistar; Reference Values; Sulfonylurea Compounds; Time Factors

1997
Effect of cholestasis on regulation of cAMP synthesis by glucagon and bile acids in isolated hepatocytes.
    The American journal of physiology, 1997, Volume: 273, Issue:1 Pt 1

    Topics: Angiotensin II; Animals; Bile; Bile Acids and Salts; Cells, Cultured; Cholestasis; Colforsin; Common Bile Duct; Cricetinae; Cyclic AMP; Glucagon; Isoenzymes; Kinetics; Liver; Male; Mesocricetus; Protein Kinase C; Protein Kinase C-alpha; Receptors, Glucagon; Reference Values; Taurocholic Acid; Ursodeoxycholic Acid

1997
Inhibition of cytokine-induced inducible nitric oxide synthase expression by glucagon and cAMP in cultured hepatocytes.
    The Biochemical journal, 1997, Aug-15, Volume: 326 ( Pt 1)

    Topics: Animals; Bucladesine; Cells, Cultured; Colforsin; Cyclic AMP; Cytokines; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; Enzyme Induction; Glucagon; Lipopolysaccharides; Liver; Male; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Time Factors

1997
Glucagon-like peptide 1 (7-36) amide stimulates exocytosis in human pancreatic beta-cells by both proximal and distal regulatory steps in stimulus-secretion coupling.
    Diabetes, 1998, Volume: 47, Issue:1

    Topics: Adult; Calcium; Calcium Channels; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Exocytosis; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Islets of Langerhans; Male; Membrane Potentials; Middle Aged; Neurotransmitter Agents; Peptide Fragments; Potassium Channels; Somatostatin

1998
Glucagon treatment interferes with an early step of duck hepatitis B virus infection.
    Journal of virology, 1998, Volume: 72, Issue:4

    Topics: Animals; Antiviral Agents; Bucladesine; Cells, Cultured; Colforsin; Cyclic AMP; Disease Susceptibility; DNA, Circular; Ducks; Gene Amplification; Glucagon; Hepadnaviridae Infections; Hepatitis B Virus, Duck; Intracellular Fluid; Time Factors; Virus Replication

1998
Glucagon-like-peptide-1 secretion from canine L-cells is increased by glucose-dependent-insulinotropic peptide but unaffected by glucose.
    Endocrinology, 1998, Volume: 139, Issue:4

    Topics: Animals; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dogs; Enteroendocrine Cells; Enzyme Activation; Enzyme Inhibitors; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucose; Immunohistochemistry; Isoquinolines; Male; Peptide Fragments; Protein Kinase C; Protein Precursors; Somatostatin; Tetradecanoylphorbol Acetate

1998
Cyclic AMP, a mediator of GLP-1, acts in concert with glucose and tolbutamide to increase cytosolic Ca2+ in pancreatic B-cells.
    Advances in experimental medicine and biology, 1997, Volume: 426

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Cytosol; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Islets of Langerhans; Peptide Fragments; Potassium Chloride; Rats; Rats, Wistar; Tolbutamide

1997
Cytochemical and biochemical studies on adenylate cyclase activity in preneoplastic and neoplastic liver tissue and cultured liver cells.
    Microscopy research and technique, 1998, Mar-15, Volume: 40, Issue:6

    Topics: Adenosine Triphosphate; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cholera Toxin; Colforsin; Enzyme Activation; Glucagon; Liver; Liver Neoplasms, Experimental; Male; Microscopy, Electron; Microscopy, Phase-Contrast; Nitrosamines; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Substrate Specificity; Time Factors

1998
Galanin inhibits glucagon-like peptide-1 secretion through pertussis toxin-sensitive G protein and ATP-dependent potassium channels in rat ileal L-cells.
    The Journal of endocrinology, 1998, Volume: 157, Issue:1

    Topics: Animals; Bombesin; Cells, Cultured; Colforsin; Disopyramide; Dose-Response Relationship, Drug; Galanin; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; GTP-Binding Proteins; Ileum; Immunohistochemistry; Male; Microscopy, Fluorescence; Peptide Fragments; Pertussis Toxin; Potassium Channels; Protein Precursors; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella

1998
Changes in G protein expression account for impaired modulation of hepatic cAMP formation after BDL.
    The American journal of physiology, 1998, Volume: 274, Issue:6

    Topics: Angiotensin II; Animals; Cholestasis; Colforsin; Common Bile Duct; Cricetinae; Cyclic AMP; Glucagon; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; GTP-Binding Proteins; Keratins; Ligation; Liver; Male; Mesocricetus; Receptors, Glucagon; Taurochenodeoxycholic Acid; Ursodeoxycholic Acid

1998
Mg2+/Ca2+ sensing inhibits hormone-stimulated Mg2+ uptake in mouse distal convoluted tubule cells.
    The American journal of physiology, 1998, Volume: 275, Issue:3

    Topics: Amiloride; Animals; Arginine Vasopressin; Calcium; Cations, Divalent; Cell Line, Transformed; Colforsin; Culture Media; Cyclic AMP; Glucagon; Kidney Tubules, Distal; Kinetics; Magnesium; Mice; Neomycin; Protein Synthesis Inhibitors

1998
High-level expression of the GLP-I receptor results in receptor desensitization.
    Pancreas, 1998, Volume: 17, Issue:3

    Topics: Animals; Cells, Cultured; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Peptide Fragments; Protein Precursors; Receptors, Glucagon; Signal Transduction; Transfection

1998
Pressure-induced expression of heat shock protein 70 mRNA in adult rat heart is coupled both to protein kinase A-dependent and protein kinase C-dependent systems.
    Journal of hypertension, 1998, Volume: 16, Issue:8

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Blood Pressure; Cardiomegaly; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Gene Expression; Glucagon; HSP70 Heat-Shock Proteins; Hypertension; In Vitro Techniques; Isoquinolines; Male; Myocardium; Naphthalenes; Perfusion; Protein Biosynthesis; Protein Kinase C; Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction; Sulfonamides

1998
Gastrectomy induces impaired insulin and glucagon secretion: evidence for a gastro-insular axis in mice.
    The Journal of physiology, 1999, Jan-15, Volume: 514 ( Pt 2)

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Blood Glucose; Carbachol; Colforsin; Cyclic AMP; Fasting; Female; Food Deprivation; Gastrectomy; Glucagon; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Mice; Mice, Inbred Strains; Parietal Cells, Gastric; Rats; Stomach; Tissue Extracts; Vagotomy

1999
Glicentin and oxyntomodulin modulate both the phosphoinositide and cyclic adenosine monophosphate signaling pathways in gastric myocytes.
    Endocrinology, 1999, Volume: 140, Issue:1

    Topics: Animals; Calcium; Carbachol; Colforsin; Cyclic AMP; Glicentin; Glucagon; Glucagon-Like Peptides; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Muscle Contraction; Muscle, Smooth; Oxyntomodulin; Peptide Fragments; Pertussis Toxin; Phosphatidylinositols; Protein Precursors; Pyloric Antrum; Rabbits; Signal Transduction; Type C Phospholipases; Virulence Factors, Bordetella

1999
Decreases in cAMP phosphodiesterase activity in hepatocytes cultured with herbimycin A due to cellular microtubule polymerization related to inhibition of tyrosine phosphorylation of alpha-tubulin.
    European journal of biochemistry, 1999, Volume: 260, Issue:2

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Benzoquinones; Cell-Free System; Cells, Cultured; Colforsin; Cyclic AMP; Enzyme Inhibitors; Glucagon; Lactams, Macrocyclic; Liver; Male; Microtubules; Phosphorylation; Polymers; Protein-Tyrosine Kinases; Quinones; Rats; Rats, Wistar; Rifabutin; Tubulin

1999
Effects of glucagon and glucagon-like peptide-1 on glucocorticoid secretion of dispersed rat adrenocortical cells.
    Life sciences, 1999, Volume: 64, Issue:24

    Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Bucladesine; Colforsin; Corticosterone; Cyclic AMP; Glucagon; Glucagon-Like Peptide 1; Glucocorticoids; In Vitro Techniques; Male; Peptide Fragments; Protein Precursors; Rats; Rats, Sprague-Dawley; Steroids

1999
Glucagon decreases cytokine induction of nitric oxide synthase and action on insulin secretion in RIN5F cells and rat and human islets of Langerhans.
    Cytokine, 1999, Volume: 11, Issue:8

    Topics: Animals; Cells, Cultured; Colforsin; Cyclic AMP; Cytokines; Enzyme Induction; Female; Gene Expression Regulation, Enzymologic; Glucagon; Humans; Insulin; Insulin Secretion; Interleukin-1; Islets of Langerhans; Kinetics; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley; Time Factors; Tumor Cells, Cultured

1999
Leptin inhibits insulin secretion induced by cellular cAMP in a pancreatic B cell line (INS-1 cells).
    The American journal of physiology, 1999, Volume: 277, Issue:4

    Topics: Animals; Calcium; Colforsin; Cyclic AMP; Cytoplasm; Enzyme Inhibitors; Glucagon; Glucagon-Like Peptide 1; Glucose; Insulin; Insulin Antagonists; Insulin Secretion; Islets of Langerhans; Leptin; Neuropeptides; Peptide Fragments; Pituitary Adenylate Cyclase-Activating Polypeptide; Protein Kinase C; Protein Precursors; Rats; Tumor Cells, Cultured

1999
Altered expression of Gi-protein and adenylyl cyclase activity in hearts from one kidney one clip hypertensive rats: effect of captopril.
    Journal of hypertension, 1999, Volume: 17, Issue:11

    Topics: Adenylyl Cyclases; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Colforsin; Glucagon; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Hypertension, Renovascular; Isoproterenol; Myocardium; Rats; Rats, Sprague-Dawley

1999
The cyclic AMP-protein kinase A pathway restrains islet phospholipase A(2) activation.
    Biochemical and biophysical research communications, 2000, Mar-05, Volume: 269, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Calcium; Carbachol; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Melitten; Peptide Fragments; Phospholipases A; Protein Precursors; Rats; Rats, Sprague-Dawley; Signal Transduction; Sincalide; Vasoactive Intestinal Peptide

2000
Membrane physical properties do not explain increased cyclic AMP production in hepatocytes from rats fed menhaden oil.
    Lipids, 2000, Volume: 35, Issue:6

    Topics: Animals; Cell Membrane; Colforsin; Cyclic AMP; Fish Oils; Glucagon; Hepatocytes; Insulin; Male; Membrane Lipids; Rats; Rats, Sprague-Dawley; Receptors, Glucagon; Signal Transduction; Spectroscopy, Fourier Transform Infrared

2000
Regulation of the diabetes-associated autoantigen IA-2 in INS-1 pancreatic beta-cells.
    Diabetes, 2000, Volume: 49, Issue:7

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Autoantigens; Colforsin; Cyclic AMP; Gene Expression Regulation; Glucagon; Glucose; Insulinoma; Islets of Langerhans; Kinetics; Membrane Proteins; Pancreatic Neoplasms; Protein Kinase C; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Rats; Receptor-Like Protein Tyrosine Phosphatases, Class 8; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Somatostatin; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

2000
Glucagon inhibits ACTH-stimulated cortisol secretion from dispersed human adrenocortical cells by activating unidentified receptors negatively coupled with the adenylate cyclase cascade.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2000, Volume: 32, Issue:7

    Topics: Adenylyl Cyclases; Adrenal Cortex; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Colforsin; Cyclic AMP; Glucagon; Humans; Hydrocortisone; Liver; Moloney murine leukemia virus; Receptors, Glucagon; Reverse Transcriptase Polymerase Chain Reaction; RNA-Directed DNA Polymerase; RNA, Messenger; Zona Fasciculata; Zona Glomerulosa

2000
Volume overload cardiac hypertrophy exhibits decreased expression of g(s)alpha and not of g(i)alpha in heart.
    American journal of physiology. Cell physiology, 2000, Volume: 279, Issue:4

    Topics: Adenylyl Cyclases; Animals; Aorta, Thoracic; Arteriovenous Shunt, Surgical; Blood Pressure; Blotting, Northern; Body Weight; Cardiomegaly; Colforsin; Glucagon; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; Guanosine 5'-O-(3-Thiotriphosphate); Isoproterenol; Male; Myocardium; Organ Size; Protein Isoforms; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sodium Fluoride

2000
Glucagon stimulates expression of the inducible cAMP early repressor and suppresses insulin gene expression in pancreatic beta-cells.
    Diabetes, 2000, Volume: 49, Issue:10

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Binding Sites; Colforsin; Cyclic AMP; Cyclic AMP Response Element Modulator; Diabetes Mellitus; DNA; DNA-Binding Proteins; Female; Gene Expression; Glucagon; Glucagon-Like Peptide 1; Insulin; Islets of Langerhans; Male; Neuropeptides; Peptide Fragments; Pituitary Adenylate Cyclase-Activating Polypeptide; Promoter Regions, Genetic; Protein Precursors; Rats; Rats, Sprague-Dawley; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2000
Vasoactive intestinal peptide regulates osteoclast activity via specific binding sites on both osteoclasts and osteoblasts.
    Bone, 2000, Volume: 27, Issue:6

    Topics: Animals; Binding Sites; Bone Resorption; Calcitonin; Calcium; Cell Movement; Cells, Cultured; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Glucagon; Microscopy, Atomic Force; Osteoblasts; Osteoclasts; Parathyroid Hormone; Rats; Rats, Sprague-Dawley; Receptors, Vasoactive Intestinal Peptide; Stromal Cells; Vasoactive Intestinal Peptide

2000
Lack of effect of incretin hormones on insulin release from pancreatic islets in the bile duct-ligated rats.
    American journal of physiology. Endocrinology and metabolism, 2001, Volume: 280, Issue:1

    Topics: Animals; Bile Ducts; Bilirubin; Bucladesine; Cholestasis, Extrahepatic; Colforsin; Cyclic AMP; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glucose Tolerance Test; Heterotrimeric GTP-Binding Proteins; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Ligation; Male; Peptide Fragments; Rats; Rats, Wistar

2001
Coregulation of glucagon-like peptide-1 synthesis with proglucagon and prohormone convertase 1 gene expression in enteroendocrine GLUTag cells.
    Endocrinology, 2001, Volume: 142, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Aspartic Acid Endopeptidases; Cell Line; Colforsin; Gene Expression Regulation; Genes, Reporter; Glucagon; Glucagon-Like Peptide 1; Intestinal Mucosa; Kinetics; Luciferases; Mice; Peptide Fragments; Proglucagon; Proprotein Convertase 1; Proprotein Convertases; Protein Precursors; Rats; Recombinant Fusion Proteins; RNA, Messenger; Transcription, Genetic; Transfection

2001
Hormone-specific combinations of isoforms of adenylyl cyclase and phosphodiesterase in the rat liver.
    Regulatory peptides, 2001, May-05, Volume: 99, Issue:1

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Animals; Calcium; Cobalt; Colforsin; Cyclic AMP; Glucagon; Glucose; In Vitro Techniques; Isoenzymes; Liver; Male; Perfusion; Rats; Rats, Wistar; Secretin; Vasoactive Intestinal Peptide

2001
Regulation of hepatic cytochrome P450 2C11 via cAMP: implications for down-regulation in diabetes, fasting, and inflammation.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 297, Issue:1

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cells, Cultured; Colforsin; Cyclic AMP; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Diabetes Mellitus; Down-Regulation; Epinephrine; Fasting; Gene Expression Regulation, Enzymologic; Glucagon; Inflammation; Insulin; Liver; Male; Rats; Rats, Sprague-Dawley; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases

2001
Defective stimulus-secretion coupling in islets of Psammomys obesus, an animal model for type 2 diabetes.
    Diabetes, 2001, Volume: 50, Issue:2

    Topics: Animals; Colforsin; Diabetes Mellitus, Type 2; Diazoxide; Disease Models, Animal; Disease Susceptibility; Gerbillinae; Glucagon; Glucagon-Like Peptide 1; Glucose; Hyperglycemia; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Isoenzymes; Oxidation-Reduction; Peptide Fragments; Protein Kinase C; Protein Precursors; Rats; Rats, Sprague-Dawley; Reference Values; Signal Transduction; Tetradecanoylphorbol Acetate

2001
Evaluation of islet heme oxygenase-CO and nitric oxide synthase-NO pathways during acute endotoxemia.
    American journal of physiology. Cell physiology, 2001, Volume: 280, Issue:5

    Topics: Animals; Blood Glucose; Carbon Monoxide; Colforsin; Cyclic AMP; Cyclic GMP; Endotoxemia; Female; Glucagon; Glucose; Heme Oxygenase (Decyclizing); In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Lipopolysaccharides; Mice; Mice, Inbred Strains; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Salmonella typhimurium; Time Factors

2001
Antiproliferative actions of growth hormone-releasing hormone antagonists on MiaPaCa-2 human pancreatic cancer cells involve cAMP independent pathways.
    Peptides, 2001, Volume: 22, Issue:6

    Topics: Adenylyl Cyclases; Animals; Cell Division; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Glucagon; Growth Hormone-Releasing Hormone; Humans; Male; Mice; Mice, Nude; Muscles; Neoplasm Transplantation; Neuropeptides; Pancreatic Neoplasms; Pituitary Adenylate Cyclase-Activating Polypeptide; Radioimmunoassay; Secretin; Signal Transduction; Tumor Cells, Cultured; Vasoactive Intestinal Peptide

2001
cAMP inhibits inducible nitric oxide synthase expression and NF-kappaB-binding activity in cultured rat hepatocytes.
    The Journal of surgical research, 2001, Volume: 99, Issue:2

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Bucladesine; Cells, Cultured; Colforsin; Cyclic AMP; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Glucagon; Hepatocytes; Interleukin-1; Male; Muscle, Smooth, Vascular; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Promoter Regions, Genetic; Pulmonary Artery; Rats; Rats, Sprague-Dawley; RNA, Messenger; Second Messenger Systems; Sepsis; Transfection

2001
Attenuation of age-related declines in glucagon-mediated signal transduction in rat liver by exercise training.
    American journal of physiology. Endocrinology and metabolism, 2001, Volume: 281, Issue:3

    Topics: Adenylyl Cyclases; Aging; Animals; Autoradiography; Cell Membrane; Colforsin; Cyclic AMP; Glucagon; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Immunoblotting; Iodine Radioisotopes; Liver; Male; Physical Endurance; Physical Exertion; Rats; Rats, Inbred F344; Receptors, Glucagon; Signal Transduction

2001
Modulation of glucagon receptor expression and response in transfected human embryonic kidney cells.
    American journal of physiology. Cell physiology, 2001, Volume: 281, Issue:4

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cell Line; Colforsin; Cyclic AMP; Dactinomycin; Enzyme Inhibitors; Gene Expression; Glucagon; GTP-Binding Proteins; Humans; Isoproterenol; Kidney; Protein Synthesis Inhibitors; Rats; Receptors, Glucagon; RNA, Messenger; Sympathomimetics; Transfection

2001
Triggering of insulin release by a combination of cAMP signal and nutrients: an ATP-sensitive K+ channel-independent phenomenon.
    Diabetes, 2002, Volume: 51 Suppl 1

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine Triphosphate; Animals; Calcium; Colforsin; Cyclic AMP; Diazoxide; Glucagon; Glucagon-Like Peptide 1; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Peptide Fragments; Phosphodiesterase Inhibitors; Potassium Channels; Protein Precursors; Rats; Rats, Wistar; Signal Transduction; Sodium Azide; Vasodilator Agents

2002
NFAT regulates insulin gene promoter activity in response to synergistic pathways induced by glucose and glucagon-like peptide-1.
    Diabetes, 2002, Volume: 51, Issue:3

    Topics: Animals; Calcineurin; Calcineurin Inhibitors; Calcium; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DNA-Binding Proteins; Drug Synergism; Enzyme Inhibitors; Gene Expression Regulation; Glucagon; Glucagon-Like Peptide 1; Glucose; Insulin; Islets of Langerhans; Isoquinolines; NFATC Transcription Factors; Nuclear Proteins; Peptide Fragments; Promoter Regions, Genetic; Protein Precursors; Rats; Sulfonamides; Tacrolimus; Transcription Factors; Transcription, Genetic

2002
Localization and function of group III metabotropic glutamate receptors in rat pancreatic islets.
    American journal of physiology. Endocrinology and metabolism, 2002, Volume: 282, Issue:6

    Topics: Animals; Benzoates; Cell Membrane; Colforsin; Cyclic AMP; Cytoplasmic Granules; DNA Primers; Excitatory Amino Acid Antagonists; Female; Gene Expression; Glucagon; Glutamic Acid; Glycine; Islets of Langerhans; Microscopy, Immunoelectron; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Reverse Transcriptase Polymerase Chain Reaction; Synaptophysin; Tissue Distribution

2002
Glucagon-like peptide 1 and fatty acids amplify pulsatile insulin secretion from perifused rat islets.
    The Biochemical journal, 2003, Jan-01, Volume: 369, Issue:Pt 1

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Colforsin; Fatty Acids; Glucagon; Glucagon-Like Peptide 1; Insulin; Insulin Secretion; Islets of Langerhans; Lipolysis; Male; Peptide Fragments; Phosphofructokinase-2; Protein Precursors; Rats; Rats, Sprague-Dawley; Rats, Wistar

2003
Time-dependent stimulation of insulin exocytosis by 3',5'-cyclic adenosine monophosphate in the rat islet beta-cell.
    Endocrinology, 2002, Volume: 143, Issue:11

    Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Bucladesine; Calcium; Cerulenin; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Exocytosis; Glucagon; Glucagon-Like Peptide 1; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Membrane Potentials; Peptide Fragments; Potassium; Protein Precursors; Rats; Rats, Wistar

2002
Glucagon-like peptide-1 receptor signaling modulates beta cell apoptosis.
    The Journal of biological chemistry, 2003, Jan-03, Volume: 278, Issue:1

    Topics: Animals; Apoptosis; beta Catenin; Blood Glucose; Cell Line; Cell Survival; Colforsin; Cricetinae; Cycloheximide; Cytokines; Cytoskeletal Proteins; Diabetes Mellitus, Experimental; Exenatide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucose Tolerance Test; In Situ Nick-End Labeling; Insulin; Islets of Langerhans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Peptide Fragments; Peptides; Protein Precursors; Protein Synthesis Inhibitors; Rats; Rats, Wistar; Receptors, Glucagon; Signal Transduction; Streptozocin; Trans-Activators; Venoms

2003
Glucagon-like peptide-1 mobilizes intracellular Ca2+ and stimulates mitochondrial ATP synthesis in pancreatic MIN6 beta-cells.
    The Biochemical journal, 2003, Jan-15, Volume: 369, Issue:Pt 2

    Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Signaling; Carbachol; Cell Line; Chelating Agents; Cholinergic Agonists; Colforsin; Cyclic AMP; Diazoxide; Egtazic Acid; Enzyme Inhibitors; Glucagon; Glucagon-Like Peptide 1; Glucose; Homeostasis; Insulin; Insulin Secretion; Islets of Langerhans; Macrocyclic Compounds; Mitochondria; Oxazoles; Peptide Fragments; Protein Precursors; Ryanodine; Ryanodine Receptor Calcium Release Channel; Thionucleotides

2003
Leptin constrains phospholipase C-protein kinase C-induced insulin secretion via a phosphatidylinositol 3-kinase-dependent pathway.
    Experimental biology and medicine (Maywood, N.J.), 2003, Volume: 228, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Androstadienes; Animals; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Glucagon; Glucagon-Like Peptide 1; Insulin; Insulin Secretion; Islets of Langerhans; Leptin; Mice; Mice, Inbred C57BL; Mice, Knockout; Peptide Fragments; Phosphatidylinositol 3-Kinases; Phosphodiesterase Inhibitors; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Protein Precursors; Signal Transduction; Type C Phospholipases; Wortmannin

2003
Mechanisms involved in glucagon-like peptide-1 (7-36) amide action on the rat hypothalamo-neurohypophysial system.
    Neuroendocrinology, 2003, Volume: 77, Issue:2

    Topics: Analysis of Variance; Angiotensin II; Animals; Calcium; Colforsin; Cyclic AMP; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Hypothalamo-Hypophyseal System; Male; Neurotransmitter Agents; Organ Culture Techniques; Oxytocin; Peptide Fragments; Rats; Rats, Wistar; Second Messenger Systems; Vasopressins; Water-Electrolyte Balance

2003
PACAP is expressed in secretory granules of insulin and glucagon cells in human and rodent pancreas. Evidence for generation of cAMP compartments uncoupled from hormone release in diabetic islets.
    Regulatory peptides, 2003, May-15, Volume: 113, Issue:1-3

    Topics: Animals; Colforsin; Cyclic AMP; Diabetes Mellitus, Type 2; Disease Models, Animal; Dose-Response Relationship, Drug; Glucagon; Glucose; Humans; Immunohistochemistry; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Microscopy, Immunoelectron; Neuropeptides; Pancreas; Pituitary Adenylate Cyclase-Activating Polypeptide; Rats; Rats, Wistar

2003
cAMP promotes pancreatic beta-cell survival via CREB-mediated induction of IRS2.
    Genes & development, 2003, Jul-01, Volume: 17, Issue:13

    Topics: Animals; Apoptosis; Cell Line; Cell Survival; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Diabetes Mellitus; Gene Expression Regulation; Glucagon; Glucagon-Like Peptide 1; Glucose; Glucose Intolerance; Humans; Insulin; Insulin Receptor Substrate Proteins; Insulin-Like Growth Factor I; Intracellular Signaling Peptides and Proteins; Islets of Langerhans; Mice; Mice, Transgenic; Peptide Fragments; Phosphoproteins; Phosphorylation; Promoter Regions, Genetic; Protein Precursors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Signal Transduction; Transfection; Transgenes; Tumor Cells, Cultured

2003
The rat pancreatic islets: a reliable tool to study islet responses to cholecystokinin receptor occupation.
    Regulatory peptides, 2004, Sep-15, Volume: 121, Issue:1-3

    Topics: 1-Methyl-3-isobutylxanthine; Adult; Animals; Blotting, Western; Colforsin; Fetus; Glucagon; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Microscopy, Confocal; Rats; Receptors, Cholecystokinin; Receptors, Somatostatin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Somatostatin

2004
Palmitate stimulation of glucagon secretion in mouse pancreatic alpha-cells results from activation of L-type calcium channels and elevation of cytoplasmic calcium.
    Diabetes, 2004, Volume: 53, Issue:11

    Topics: Animals; Colforsin; Diazoxide; Glucagon; Islets of Langerhans; Isradipine; Kinetics; Membrane Potentials; Mice; Mice, Inbred Strains; Palmitic Acid; Potassium; Triazenes

2004
cAMP-dependent tyrosine phosphorylation of subunit I inhibits cytochrome c oxidase activity.
    The Journal of biological chemistry, 2005, Feb-18, Volume: 280, Issue:7

    Topics: Allosteric Regulation; Amino Acid Sequence; Animals; Cattle; Colforsin; Crystallography, X-Ray; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Electron Transport Complex IV; Glucagon; Kinetics; Liver; Lung; Models, Molecular; Myocardium; Phosphorylation; Phosphotyrosine; Protein Conformation; Protein Subunits; Theophylline

2005
Modulation of glycogen phosphorylase activity affects 5-phosphoribosyl-1-pyrophosphate availability in rat hepatocyte cultures.
    Nucleosides, nucleotides & nucleic acids, 2004, Volume: 23, Issue:8-9

    Topics: Amides; Animals; Arginine Vasopressin; Bucladesine; Caffeine; Colforsin; Cyclic AMP-Dependent Protein Kinases; Glucagon; Glycogen Phosphorylase; Hepatocytes; Indoles; Liver; Male; Phenylephrine; Phosphoribosyl Pyrophosphate; Rats; Rats, Wistar; Time Factors

2004
Free fatty acids increase PGC-1alpha expression in isolated rat islets.
    FEBS letters, 2005, Feb-28, Volume: 579, Issue:6

    Topics: Animals; Cells, Cultured; Colforsin; Fatty Acids, Nonesterified; Gene Expression Regulation; Glucagon; Glucagon-Like Peptide 1; Glucose; Islets of Langerhans; Liver; Male; Mice; Peptide Fragments; Protein Precursors; Rats; Rats, Wistar; RNA, Messenger; RNA, Small Interfering; Transcription Factors

2005
Effects of the C-terminal peptide of the alphaS subunit of the G protein on the regulation of adenylyl cyclase and protein kinase A activities by biogenic amines and glucagon in mollusk and rat muscles.
    Neuroscience and behavioral physiology, 2005, Volume: 35, Issue:2

    Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Biogenic Monoamines; Cell Membrane; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Drug Interactions; Glucagon; GTP-Binding Protein alpha Subunits; Guanylyl Imidodiphosphate; Isoproterenol; Mollusca; Muscles; Peptides; Rats; Sodium Fluoride

2005
PKA independent and cell type specific activation of the expression of caudal homeobox gene Cdx-2 by cyclic AMP.
    The FEBS journal, 2005, Volume: 272, Issue:11

    Topics: Animals; CDX2 Transcription Factor; Colforsin; Colonic Neoplasms; Cricetinae; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enteroendocrine Cells; Genes, Dominant; Glucagon; Guanine Nucleotide Exchange Factors; Homeodomain Proteins; Humans; Intestinal Mucosa; Intestinal Polyps; Intestines; Islets of Langerhans; Mice; Mice, Knockout; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Proglucagon; Protein Precursors; Signal Transduction; Transcription Factors

2005
p38 Mitogen-activated protein kinase plays a stimulatory role in hepatic gluconeogenesis.
    The Journal of biological chemistry, 2005, Dec-30, Volume: 280, Issue:52

    Topics: Acetylcysteine; Adenoviridae; Animals; Cell Line, Tumor; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Diabetes Mellitus, Type 1; Disease Models, Animal; Enzyme Inhibitors; Gene Silencing; Glucagon; Gluconeogenesis; Glucose; Glucose-6-Phosphatase; Hepatocytes; Imidazoles; Liver; Mice; p38 Mitogen-Activated Protein Kinases; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phosphoenolpyruvate Carboxykinase (GTP); Phosphorylation; Promoter Regions, Genetic; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Streptozocin; Trans-Activators; Transcription Factors; Transfection

2005
Enhanced expression of Gialpha protein and adenylyl cyclase signaling in aortas from 1 kidney 1 clip hypertensive rats.
    Canadian journal of physiology and pharmacology, 2006, Volume: 84, Issue:7

    Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Angiotensin II; Animals; Antihypertensive Agents; Aorta; Atrial Natriuretic Factor; Captopril; Colforsin; Dose-Response Relationship, Drug; Glucagon; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine 5'-O-(3-Thiotriphosphate); Hypertension, Renovascular; Immunoblotting; Isoproterenol; Peptide Fragments; Rats; Rats, Sprague-Dawley; Renal Artery Obstruction; Signal Transduction; Sodium Fluoride; Time Factors

2006
Glucose release as a response to glucagon in rat hepatocyte culture: involvement of NO signaling.
    Physiological research, 2008, Volume: 57, Issue:4

    Topics: Animals; Bucladesine; Cell Separation; Cells, Cultured; Colforsin; Glucagon; Glucose; Glycogen; Guanidines; Hepatocytes; Male; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; S-Nitroso-N-Acetylpenicillamine; Signal Transduction

2008
Function and expression of melatonin receptors on human pancreatic islets.
    Journal of pineal research, 2008, Volume: 44, Issue:3

    Topics: Animals; Cell Line, Tumor; Colforsin; Cyclic AMP; Glucagon; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Mice; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Receptors, Melatonin; RNA, Messenger; Second Messenger Systems

2008
Inhibition of glucagon-signaling and downstream actions by interleukin 1beta and tumor necrosis factor alpha in cultured primary rat hepatocytes.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2008, Volume: 40, Issue:1

    Topics: Animals; Cells, Cultured; Colforsin; Cyclic AMP; Gene Expression Regulation, Enzymologic; Glucagon; Glucokinase; Glucose; Glycogen; Hepatocytes; Humans; Insulin; Interleukin-1beta; Male; Phosphoenolpyruvate Carboxykinase (GTP); Rats; Rats, Wistar; Recombinant Proteins; RNA, Messenger; Signal Transduction; Tumor Necrosis Factor-alpha

2008
Glucagon receptor mediates calcium signaling by coupling to G alpha q/11 and G alpha i/o in HEK293 cells.
    Journal of receptor and signal transduction research, 2009, Volume: 29, Issue:6

    Topics: Calcium; Calcium Signaling; Cell Line; Colforsin; Cyclic AMP; Enzyme Inhibitors; Glucagon; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gq-G11; Humans; Pertussis Toxin; Receptors, Glucagon; RNA Interference; Signal Transduction; Thapsigargin

2009
GLP-1 inhibits and adrenaline stimulates glucagon release by differential modulation of N- and L-type Ca2+ channel-dependent exocytosis.
    Cell metabolism, 2010, Jun-09, Volume: 11, Issue:6

    Topics: Animals; Calcium Channels, L-Type; Calcium Channels, N-Type; Carrier Proteins; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Epinephrine; Exocytosis; Glucagon; Glucagon-Like Peptide 1; Guanine Nucleotide Exchange Factors; Islets of Langerhans; Membrane Potentials; Mice; Mice, Inbred C57BL

2010
Glucagon stimulates hepatic FGF21 secretion through a PKA- and EPAC-dependent posttranscriptional mechanism.
    PloS one, 2014, Volume: 9, Issue:4

    Topics: AMP-Activated Protein Kinases; Animals; Bucladesine; Colforsin; Cyclic AMP-Dependent Protein Kinases; Fibroblast Growth Factors; Glucagon; Guanine Nucleotide Exchange Factors; Hep G2 Cells; Humans; Insulin; Liver; Male; Models, Biological; p38 Mitogen-Activated Protein Kinases; rap1 GTP-Binding Proteins; Rats, Sprague-Dawley; RNA, Messenger; Transcription, Genetic

2014
Post-Translational Regulation of the Glucose-6-Phosphatase Complex by Cyclic Adenosine Monophosphate Is a Crucial Determinant of Endogenous Glucose Production and Is Controlled by the Glucose-6-Phosphate Transporter.
    Journal of proteome research, 2016, Apr-01, Volume: 15, Issue:4

    Topics: Adenoviruses, Human; Animals; Antiporters; Caco-2 Cells; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Epithelial Cells; Gene Expression Regulation; Genetic Vectors; Glucagon; Glucose; Glucose-6-Phosphatase; Glucose-6-Phosphate; Hep G2 Cells; Humans; Monosaccharide Transport Proteins; Mutagenesis, Site-Directed; Phosphorylation; Protein Biosynthesis; Protein Subunits; Rats; Signal Transduction

2016
CFTR is involved in the regulation of glucagon secretion in human and rodent alpha cells.
    Scientific reports, 2017, 03-07, Volume: 7, Issue:1

    Topics: Animals; Cells, Cultured; Colforsin; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Female; Glucagon; Glucagon-Secreting Cells; Glucose; Humans; Male; Membrane Potentials; Mice; Middle Aged; Mutation; Somatostatin-Secreting Cells

2017
Pancreatic α- and β-cellular clocks have distinct molecular properties and impact on islet hormone secretion and gene expression.
    Genes & development, 2017, 02-15, Volume: 31, Issue:4

    Topics: Animals; Cells, Cultured; Circadian Clocks; Colforsin; Enzyme Activators; Gene Expression Profiling; Gene Expression Regulation; Glucagon; Glucagon-Secreting Cells; Insulin; Insulin Secretion; Insulin-Secreting Cells; Mice; Models, Animal; Sequence Analysis, RNA; Time Factors

2017
26S Proteasomes are rapidly activated by diverse hormones and physiological states that raise cAMP and cause Rpn6 phosphorylation.
    Proceedings of the National Academy of Sciences of the United States of America, 2019, 03-05, Volume: 116, Issue:10

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Colforsin; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Epinephrine; Glucagon; Hepatocytes; Humans; Kidney; Male; Mice; Muscle, Skeletal; Phosphorylation; Proteasome Endopeptidase Complex; Proteolysis; Proteostasis Deficiencies; Rats; Rats, Sprague-Dawley; Rats, Wistar; Ubiquitinated Proteins

2019
O-GlcNAcylated p53 in the liver modulates hepatic glucose production.
    Nature communications, 2021, 08-20, Volume: 12, Issue:1

    Topics: Acetylglucosamine; Animals; Base Sequence; Caloric Restriction; Cell Line; Colforsin; Diabetes Mellitus, Type 2; Epinephrine; Glucagon; Glucocorticoids; Gluconeogenesis; Glucose; Glycosylation; Hepatocytes; Humans; Hydrocortisone; Hyperglycemia; Insulin Resistance; Intracellular Signaling Peptides and Proteins; Liver; Mice, Inbred C57BL; Mice, Knockout; Obesity; Phosphoenolpyruvate Carboxykinase (GTP); Promoter Regions, Genetic; Protein Binding; Protein Stability; Pyruvic Acid; RNA, Messenger; Transcription, Genetic; Tumor Suppressor Protein p53

2021