Page last updated: 2024-09-04

glucagon and 8-bromo cyclic adenosine monophosphate

glucagon has been researched along with 8-bromo cyclic adenosine monophosphate in 57 studies

Compound Research Comparison

Studies
(glucagon)
Trials
(glucagon)
Recent Studies (post-2010)
(glucagon)
Studies
(8-bromo cyclic adenosine monophosphate)
Trials
(8-bromo cyclic adenosine monophosphate)
Recent Studies (post-2010) (8-bromo cyclic adenosine monophosphate)
26,0391,4983,0543,7075198

Protein Interaction Comparison

ProteinTaxonomyglucagon (IC50)8-bromo cyclic adenosine monophosphate (IC50)
cAMP-specific 3',5'-cyclic phosphodiesterase 4AHomo sapiens (human)7.7
cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)7.7
cAMP-specific 3',5'-cyclic phosphodiesterase 4CHomo sapiens (human)7.7
cAMP-specific 3',5'-cyclic phosphodiesterase 4DHomo sapiens (human)7.7

Research

Studies (57)

TimeframeStudies, this research(%)All Research%
pre-199012 (21.05)18.7374
1990's35 (61.40)18.2507
2000's7 (12.28)29.6817
2010's3 (5.26)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jamil, H; Utal, AK; Vance, DE1
Allmann, DW; Behforouz, H; Chikada, K; DePaoli-Roach, A; Dominianni, SJ; Harris, RA; Scislowski, P; Stephens, TW; Yamanouchi, K1
Somogyi, R; Stucki, JW; Zhao, M1
Iyengar, R; Jacobowitz, O; Premont, RT1
Bataille, D; Demirpence, E; Gros, L; Jarrousse, C; Kervran, A1
Houslay, MD; Tang, EK1
Grapengiesser, E; Gylfe, E; Hellman, B1
Flores-Riveros, JR; Janicot, M; Kaestner, KH; Lane, MD; McLenithan, JC1
Fain, JN; Pittner, RA2
Bushfield, M; Houslay, MD; Lavan, BE1
Bushfield, M; Houslay, MD; Hruby, VJ; Lavan, BE; Milligan, G; Murphy, GJ; Parker, PJ1
Good, DW1
Danoff, A; Fleischer, N; Pasmantier, R; Schubart, UK1
Campbell, RM; Scanes, CG1
Christoffersen, T; Johansen, EJ; Refsnes, M1
Eckert, RW; Petzelt, C; Raue, F; Scherübl, H; Ziegler, R1
Beckner, SK; Darfler, FJ; Lin, MC1
Evoniuk, G; Kuhn, CM; Schanberg, SM1
Kizaki, Z; Thurman, RG1
Brass, EP; Garrity, MJ1
Christoffersen, T; Refsnes, M; Sandnes, D1
Dickson, AJ; Fisher, MJ; Pogson, CI1
Crettaz, M; Jeanrenaud, B; Prentki, M1
Absood, A; Maruno, K; Said, SI1
Habener, JF; Holz, GG; Leech, CA2
Brosnan, JT; Ewart, HS; Squires, SA1
Clemens, MG; De Maio, A; Deutschman, CS1
Kong, X; Lawrence, JC; Sevetson, BR1
Bode, HP; Fehmann, HC; Göke, B; Williams, JA; Yule, DI1
Bushfield, M; Houslay, MD; Lavan, BE; Morris, NJ1
Funai, T; Ichiyama, A; Oda, T; Ohbayashi, K; Uchida, C1
Gillin, AG; Isozaki, T; Sands, JM; Swanson, CE1
Janssens, PA; Kleineke, JW1
Garcia-Jimenez, C; Hernandez, A; Obregon, MJ; Santisteban, P1
Botham, KM; Cho-Chung, YS; Hoang, VQ; Suckling, KE1
Brass, EP; Vetter, WH1
Christoffersen, T; Jacobsen, FW; Refsnes, M; Sandnes, D1
Kuestner, RE; Moore, EE; Stroop, SD; Thompson, DL1
Pavoine, C; Pecker, F; Rohn, T; Sauvadet, A2
Bernemann, IK; Verspohl, EJ1
Bendayan, M; De Bie, I; Lazure, C; Malide, D; Marcinkiewicz, M; Nakayama, K; Seidah, NG1
Bapty, B; Dai, LJ; Quamme, GA; Ritchie, G1
Bouchelouche, P; Gromada, J; Hansen, LH; Jelinek, L; Kindsvogel, W; Nishimura, E; Whitmore, T1
Egan, JM; Janczewski, AM; Montrose-Rafizadeh, C; Pineyro, MA; Sollott, SJ; Wang, Y; Zhou, J1
Fagan, TE; Romani, A1
Ganster, RW; Geller, DA; Harbrecht, BG; Ramalakshmi, S; Taylor, BS; Xu, Z1
Bouscarel, B; Cypess, AM; Ikegami, T1
Busby, ER; Hallgren, NK; Mommsen, TP1
Clemens, MG; Lee, SM1
Chiang, JY; Song, KH1
Kurland, IJ; Pei, L; Tontonoz, P; Vaitheesvaran, B; Waki, H; Wilpitz, DC1
Campbell, JS; Clementi, AH; Gaudy, AM; Mooney, RA; Smrcka, AV1
Anini, Y; Gagnon, J1
Goldberg, AL; Lokireddy, S; VerPlank, JJS; Zhao, J1

Reviews

1 review(s) available for glucagon and 8-bromo cyclic adenosine monophosphate

ArticleYear
Signal transduction of PACAP and GLP-1 in pancreatic beta cells.
    Annals of the New York Academy of Sciences, 1996, Dec-26, Volume: 805

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium; Cyclic GMP; Glucagon; Glucagon-Like Peptide 1; Ion Channels; Islets of Langerhans; Membrane Potentials; Models, Biological; Neuropeptides; Peptide Fragments; Pituitary Adenylate Cyclase-Activating Polypeptide; Protein Precursors; Rats; Signal Transduction

1996

Other Studies

56 other study(ies) available for glucagon and 8-bromo cyclic adenosine monophosphate

ArticleYear
Evidence that cyclic AMP-induced inhibition of phosphatidylcholine biosynthesis is caused by a decrease in cellular diacylglycerol levels in cultured rat hepatocytes.
    The Journal of biological chemistry, 1992, Jan-25, Volume: 267, Issue:3

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amino Acid Sequence; Animals; Antibodies; Bucladesine; Carbon Radioisotopes; Cells, Cultured; Choline; Choline-Phosphate Cytidylyltransferase; Cyclic AMP; Diacylglycerol Cholinephosphotransferase; Diglycerides; Glucagon; Kinetics; Liver; Male; Molecular Sequence Data; Nucleotidyltransferases; Peptides; Phosphatidylcholines; Radioisotope Dilution Technique; Rats; Rats, Inbred Strains; Thionucleotides; Tritium

1992
Metabolic effects of proglycosyn.
    Archives of biochemistry and biophysics, 1992, May-01, Volume: 294, Issue:2

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Atropine; Cells, Cultured; Cyclic AMP; Glucagon; Glycogen Synthase; Hypoglycemic Agents; Imidazoles; Kinetics; Liver; Liver Glycogen; Male; Phosphoprotein Phosphatases; Phosphorylase a; Rats; Rats, Inbred Strains; Verapamil

1992
Modulation of cytosolic-[Ca2+] oscillations in hepatocytes results from cross-talk among second messengers. The synergism between the alpha 1-adrenergic response, glucagon and cyclic AMP, and their antagonism by insulin and diacylglycerol manifest themsel
    The Biochemical journal, 1992, Sep-15, Volume: 286 ( Pt 3)

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Benzimidazoles; Calcium; Calmodulin; Cations, Divalent; Cells, Cultured; Colforsin; Cyclic AMP; Cytosol; Diglycerides; Drug Synergism; Glucagon; Imidazoles; Insulin; Liver; Phenylephrine; Protein Kinase C; Rats; Second Messenger Systems; Thionucleotides

1992
Lowered responsiveness of the catalyst of adenylyl cyclase to stimulation by GS in heterologous desensitization: a role for adenosine 3',5'-monophosphate-dependent phosphorylation.
    Endocrinology, 1992, Volume: 131, Issue:6

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Amino Acid Sequence; Animals; Base Sequence; Cell Membrane; Chickens; Cyclic AMP; DNA; Glucagon; GTP-Binding Proteins; Liver; Molecular Sequence Data; Phosphorylation; Polymerase Chain Reaction; Protein Kinases; Rats; Sodium Fluoride; Vasoactive Intestinal Peptide

1992
Characterization of binding sites for oxyntomodulin on a somatostatin-secreting cell line (RIN T3).
    Endocrinology, 1992, Volume: 130, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Animals; Binding Sites; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Glucagon; Glucagon-Like Peptides; Insulinoma; Iodine Radioisotopes; Oxyntomodulin; Rats; Somatostatin; Tumor Cells, Cultured

1992
Glucagon, vasopressin and angiotensin all elicit a rapid, transient increase in hepatocyte protein kinase C activity.
    The Biochemical journal, 1992, Apr-15, Volume: 283 ( Pt 2)

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Angiotensin II; Animals; Cell Membrane; Cells, Cultured; Cytosol; Enzyme Activation; Glucagon; Kinetics; Liver; Male; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Vasopressins

1992
Cyclic AMP as a determinant for glucose induction of fast Ca2+ oscillations in isolated pancreatic beta-cells.
    The Journal of biological chemistry, 1991, Jul-05, Volume: 266, Issue:19

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium; Cyclic AMP; Fura-2; Glucagon; Glucose; In Vitro Techniques; Islets of Langerhans; Mice; Spectrometry, Fluorescence

1991
Transcriptional repression of the mouse insulin-responsive glucose transporter (GLUT4) gene by cAMP.
    Proceedings of the National Academy of Sciences of the United States of America, 1991, Mar-01, Volume: 88, Issue:5

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adipose Tissue; Animals; Antisense Elements (Genetics); Cell Line; Cell Nucleus; Colforsin; Cyclic AMP; Deoxyglucose; Glucagon; Isoproterenol; Kinetics; Mice; Monosaccharide Transport Proteins; RNA; Transcription, Genetic

1991
Activation of membrane protein kinase C by glucagon and Ca(2+)-mobilizing hormones in cultured rat hepatocytes. Role of phosphatidylinositol and phosphatidylcholine hydrolysis.
    The Biochemical journal, 1991, Jul-15, Volume: 277 ( Pt 2)

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Angiotensin II; Animals; Calcimycin; Cell Membrane; Cells, Cultured; Enzyme Activation; Glucagon; Hydrolysis; Inositol Phosphates; Kinetics; Liver; Myristic Acid; Myristic Acids; Norepinephrine; Phosphatidylcholines; Phosphatidylinositols; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Vasopressins

1991
Okadaic acid identifies a phosphorylation/dephosphorylation cycle controlling the inhibitory guanine-nucleotide-binding regulatory protein Gi2.
    The Biochemical journal, 1991, Mar-01, Volume: 274 ( Pt 2)

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Animals; Cells, Cultured; Ethers, Cyclic; Glucagon; GTP-Binding Proteins; Ionophores; Kinetics; Liver; Macromolecular Substances; Male; Okadaic Acid; Phosphorylation; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Vasopressins

1991
Hormonal regulation of Gi2 alpha-subunit phosphorylation in intact hepatocytes.
    The Biochemical journal, 1990, Jun-01, Volume: 268, Issue:2

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amino Acids; Angiotensin II; Animals; Cell Membrane; Dose-Response Relationship, Drug; Glucagon; GTP-Binding Proteins; Hormones; Kinetics; Liver; Organophosphorus Compounds; Phosphorylation; Precipitin Tests; Protein Kinase C; Rats; Rats, Inbred Strains; Vasopressins

1990
Inhibition of bicarbonate absorption by peptide hormones and cyclic adenosine monophosphate in rat medullary thick ascending limb.
    The Journal of clinical investigation, 1990, Volume: 85, Issue:4

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Absorption; Ammonia; Animals; Arginine Vasopressin; Bicarbonates; Biological Transport; Colforsin; Furosemide; Glucagon; In Vitro Techniques; Kidney Medulla; Kidney Tubules; Loop of Henle; Male; Parathyroid Hormone; Rats; Rats, Inbred Strains; Sodium Chloride

1990
P19, a hormonally regulated phosphoprotein of peptide hormone-producing cells: secretagogue-induced phosphorylation in AtT-20 mouse pituitary tumor cells and in rat and hamster insulinoma cells.
    Endocrinology, 1986, Volume: 119, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenoma, Islet Cell; Adrenocorticotropic Hormone; Animals; Colforsin; Corticotropin-Releasing Hormone; Cricetinae; Cyclic AMP; Electrophoresis, Polyacrylamide Gel; Glucagon; Insulinoma; Isoproterenol; Pancreatic Neoplasms; Phosphoproteins; Phosphorylation; Pituitary Neoplasms; Potassium; Rats; Tetradecanoylphorbol Acetate

1986
Growth hormone inhibition of glucagon- and cAMP-induced lipolysis by chicken adipose tissue in vitro.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1987, Volume: 184, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adipose Tissue; Animals; Chickens; Cyclic AMP; Glucagon; Growth Hormone; Lipolysis; Male

1987
Glucagon-induced refractoriness of hepatocyte adenylate cyclase: comparison of homologous and heterologous components and evidence against a role of cAMP.
    Pharmacology & toxicology, 1989, Volume: 64, Issue:5

    Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Animals; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Glucagon; Isoproterenol; Liver; Male; Rats; Rats, Inbred Strains

1989
Exposure of cultured hepatocytes to cyclic AMP enhances the vasopressin-mediated stimulation of inositol phosphate production.
    The Biochemical journal, 1989, Jan-15, Volume: 257, Issue:2

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cells, Cultured; Cyclic GMP; Cycloheximide; Dactinomycin; Dexamethasone; Dose-Response Relationship, Drug; Glucagon; Inositol Phosphates; Liver; Rats; Sugar Phosphates; Vasopressins

1989
Rhythmic oscillations of cytosolic free calcium in rat C-cells.
    Molecular and cellular endocrinology, 1989, Volume: 64, Issue:2

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Benzofurans; Calcium; Carcinoma; Cyclic AMP; Cytosol; Fluorescent Dyes; Fura-2; Glucagon; Rats; Thyroid Neoplasms; Tumor Cells, Cultured

1989
Induction of glucagon sensitivity in a transformed kidney cell line by prostaglandin E2 and its inhibition by epidermal growth factor.
    Molecular and cellular biology, 1987, Volume: 7, Issue:12

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Blood; Cell Differentiation; Cell Line, Transformed; Cyclic AMP; Dinoprostone; Dogs; Epidermal Growth Factor; Glucagon; Kidney; Prostaglandins; Prostaglandins E; Tetradecanoylphorbol Acetate

1987
Hepatic cyclic AMP generation and ornithine decarboxylase induction by glucagon and beta adrenergic agonists.
    Life sciences, 1985, May-27, Volume: 36, Issue:21

    Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aminophylline; Animals; Bucladesine; Corticosterone; Cyclic AMP; Enzyme Induction; Food Deprivation; Glucagon; Growth Hormone; Isoproterenol; Kinetics; Liver; Ornithine Decarboxylase; Rats; Rats, Inbred Strains; Tyrosine Transaminase

1985
Stimulation of oxygen uptake by glucagon is oxygen dependent in perfused rat liver.
    The American journal of physiology, 1989, Volume: 256, Issue:2 Pt 1

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Female; Glucagon; Glucose; Kinetics; Lactates; Liver; Mitochondria, Liver; Oxygen Consumption; Perfusion; Pyruvates; Rats; Rats, Inbred Strains; Reference Values

1989
Effect of E-series prostaglandins on cyclic AMP-dependent and -independent hormone-stimulated glycogenolysis in hepatocytes.
    Diabetes, 1985, Volume: 34, Issue:3

    Topics: 16,16-Dimethylprostaglandin E2; 8-Bromo Cyclic Adenosine Monophosphate; Angiotensin II; Animals; Bucladesine; Calcimycin; Cyclic AMP; Dose-Response Relationship, Drug; Epinephrine; Glucagon; Liver; Liver Glycogen; Male; Phenylephrine; Prostaglandins E; Rats; Rats, Inbred Strains

1985
The relationship between beta-adrenoceptor regulation and beta-adrenergic responsiveness in hepatocytes. Studies on acquisition, desensitization and resensitization of isoproterenol-sensitive adenylate cyclase in primary culture.
    European journal of biochemistry, 1987, Mar-16, Volume: 163, Issue:3

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Glucagon; Iodocyanopindolol; Isoproterenol; Liver; Male; Pertussis Toxin; Pindolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Time Factors; Virulence Factors, Bordetella

1987
The role of insulin in the modulation of glucagon-dependent control of phenylalanine hydroxylation in isolated liver cells.
    The Biochemical journal, 1987, Mar-15, Volume: 242, Issue:3

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cell Separation; Cyclic GMP; Dose-Response Relationship, Drug; Glucagon; Hydroxylation; In Vitro Techniques; Insulin; Liver; Male; Phenylalanine; Phenylalanine Hydroxylase; Rats; Rats, Inbred Strains; Vanadates; Vanadium

1987
Role of microtubules in insulin and glucagon stimulation of amino acid transport in isolated rat hepatocytes.
    The Journal of biological chemistry, 1981, May-10, Volume: 256, Issue:9

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Aminoisobutyric Acids; Animals; Biological Transport; Colchicine; Cyclic AMP; Glucagon; In Vitro Techniques; Insulin; Kinetics; Liver; Male; Microtubules; Rats; Vinblastine

1981
VIP inhibits basal and histamine-stimulated proliferation of human airway smooth muscle cells.
    The American journal of physiology, 1995, Volume: 268, Issue:6 Pt 1

    Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Carbazoles; Cell Cycle; Cell Division; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DNA; Dose-Response Relationship, Drug; Glucagon; Histamine; Histamine Antagonists; Humans; Indoles; Kinetics; Muscle, Smooth; Pyrroles; Thymidine; Trachea; Vasoactive Intestinal Peptide

1995
Activation of a cAMP-regulated Ca(2+)-signaling pathway in pancreatic beta-cells by the insulinotropic hormone glucagon-like peptide-1.
    The Journal of biological chemistry, 1995, Jul-28, Volume: 270, Issue:30

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium; Cell Line; Cyclic AMP; Glucagon; Glucagon-Like Peptide 1; Insulinoma; Ion Channels; Islets of Langerhans; Membrane Potentials; Peptide Fragments; Protein Precursors; Rats; Signal Transduction; Tumor Cells, Cultured

1995
Hormonal control of hepatic glutaminase.
    Advances in enzyme regulation, 1995, Volume: 35

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Diabetes Mellitus, Experimental; Dietary Proteins; Endotoxins; Enzyme Activation; Enzyme Inhibitors; Ethers, Cyclic; Glucagon; Glutamic Acid; Glutaminase; Glutamine; Mitochondria, Liver; Okadaic Acid; Phosphates; Rats; Signal Transduction; Thionucleotides

1995
Sepsis-induced attenuation of glucagon and 8-BrcAMP modulation of the phosphoenolpyruvate carboxykinase gene.
    The American journal of physiology, 1995, Volume: 269, Issue:3 Pt 2

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bacterial Infections; Fibrinogen; Gene Expression; Glucagon; Male; Perfusion; Phosphoenolpyruvate Carboxykinase (GTP); Rats; Rats, Sprague-Dawley

1995
Increasing cAMP attenuates activation of mitogen-activated protein kinase.
    Proceedings of the National Academy of Sciences of the United States of America, 1993, Nov-01, Volume: 90, Issue:21

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adipocytes; Animals; Bucladesine; Calcium-Calmodulin-Dependent Protein Kinases; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Epididymis; Glucagon; Isoenzymes; Isoproterenol; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphoproteins; Phosphotyrosine; Rats; Rats, Sprague-Dawley; Thionucleotides; Tyrosine

1993
Spontaneous calcium oscillations in clonal endocrine pancreatic glucagon-secreting cells.
    Biochemical and biophysical research communications, 1994, Nov-30, Volume: 205, Issue:1

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Alkaloids; Calcium; Cell Line; Cyclic GMP; Estrenes; Glucagon; Pancreas; Protein Kinase C; Pyrrolidinones; Staurosporine; Terpenes; Thapsigargin; Type C Phospholipases

1994
Multi-site phosphorylation of the inhibitory guanine nucleotide regulatory protein Gi-2 occurs in intact rat hepatocytes.
    The Biochemical journal, 1994, Aug-01, Volume: 301 ( Pt 3)

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amino Acid Sequence; Animals; Binding Sites; Colforsin; Glucagon; GTP-Binding Proteins; Immunosorbent Techniques; Isoelectric Point; Liver; Male; Molecular Sequence Data; Peptide Fragments; Phosphorylation; Phosphoserine; Rats; Rats, Sprague-Dawley; Serine Endopeptidases; Tetradecanoylphorbol Acetate; Trypsin; Vasopressins

1994
Regulation by glucagon of serine: pyruvate/alanine: glyoxylate aminotransferase gene expression in cultured rat hepatocytes.
    The Journal of biological chemistry, 1994, Mar-25, Volume: 269, Issue:12

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Alanine Transaminase; Animals; Calcimycin; Cells, Cultured; Cycloheximide; Dexamethasone; Enzyme Induction; Gene Expression; Glucagon; In Vitro Techniques; Liver; Male; Promoter Regions, Genetic; Rats; Rats, Wistar; RNA, Messenger; Tetradecanoylphorbol Acetate; Transaminases; Transcription, Genetic

1994
Protein restriction sequentially induces new urea transport processes in rat initial IMCD.
    The American journal of physiology, 1994, Volume: 266, Issue:5 Pt 2

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Aldehyde Reductase; Animals; Arginine Vasopressin; Blood Proteins; Creatinine; Cyclic AMP; Dietary Proteins; Glucagon; Kidney Medulla; Kidney Tubules, Collecting; Male; Rats; Rats, Sprague-Dawley; Serum Albumin; Urea

1994
Hormone-induced rise in cytosolic Ca2+ in axolotl hepatocytes: extracellular origin and control by cAMP.
    The American journal of physiology, 1993, Volume: 265, Issue:5 Pt 1

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Ambystoma mexicanum; Animals; Calcium; Cells, Cultured; Cyclic AMP; Cytosol; Epinephrine; Glucagon; Guanosine Triphosphate; Inositol 1,4,5-Trisphosphate; Isoproterenol; Kinetics; Liver; Phentolamine; Propranolol; Thionucleotides; Vasotocin

1993
Regulation of malic-enzyme-gene expression by cAMP and retinoic acid in differentiating brown adipocytes.
    European journal of biochemistry, 1993, Jul-15, Volume: 215, Issue:2

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adipose Tissue; Animals; Cell Differentiation; Cells, Cultured; Colforsin; Cyclic AMP; Gene Expression Regulation, Enzymologic; Glucagon; Insulin; Malate Dehydrogenase; Norepinephrine; Rats; RNA, Messenger; Tretinoin; Triiodothyronine

1993
The effect of cyclic AMP analogues and glucagon on cholesteryl ester synthesis and hydrolysis in cultured hamster hepatocytes.
    FEBS letters, 1993, Aug-23, Volume: 329, Issue:1-2

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cells, Cultured; Cholesterol Esters; Cricetinae; Cyclic AMP; Glucagon; Hydrolysis; Liver; Male; Mesocricetus; Oleic Acid; Oleic Acids; Theophylline; Thionucleotides; Triglycerides

1993
Inhibition of glucagon-stimulated glycogenolysis by S-nitroso-N-acetylpenicillamine.
    Pharmacology & toxicology, 1993, Volume: 72, Issue:6

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cells, Cultured; Cyclic GMP; Glucagon; Glucose; Liver; Liver Glycogen; Male; Nitric Oxide; Penicillamine; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; Vasodilator Agents

1993
Long-term inhibitory effect of cAMP on beta-adrenoceptor acquisition and nonselective attenuation of adenylyl cyclase in hepatocytes.
    European journal of pharmacology, 1993, Jul-15, Volume: 246, Issue:2

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Down-Regulation; Glucagon; Iodocyanopindolol; Isoproterenol; Liver; Male; Pindolol; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Thionucleotides

1993
A recombinant human calcitonin receptor functions as an extracellular calcium sensor.
    The Journal of biological chemistry, 1993, Sep-25, Volume: 268, Issue:27

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcitonin; Calcium; Cell Line; Cell Membrane; Cloning, Molecular; Colforsin; Cricetinae; Cyclic AMP; Cytosol; Glucagon; Humans; Kidney; Kinetics; Receptors, Calcitonin; Receptors, Cell Surface; Recombinant Proteins; Time Factors; Transfection

1993
Synergistic actions of glucagon and miniglucagon on Ca2+ mobilization in cardiac cells.
    Circulation research, 1996, Volume: 78, Issue:1

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Chick Embryo; Drug Synergism; Glucagon; Heart Ventricles; Isradipine; Peptide Fragments; Sarcoplasmic Reticulum

1996
Atrial natriuretic peptide (ANP)-induced inhibition of glucagon secretion: mechanism of action in isolated rat pancreatic islets.
    Peptides, 1996, Volume: 17, Issue:6

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Atrial Natriuretic Factor; Calcium; Dose-Response Relationship, Drug; Female; Glucagon; Glucose; GTP-Binding Proteins; In Vitro Techniques; Islets of Langerhans; Nickel; Pertussis Toxin; Polysaccharides; Protein Kinase C; Rats; Rats, Wistar; Receptors, Atrial Natriuretic Factor; Second Messenger Systems; Virulence Factors, Bordetella

1996
The isoforms of proprotein convertase PC5 are sorted to different subcellular compartments.
    The Journal of cell biology, 1996, Volume: 135, Issue:5

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amino Acid Sequence; Animals; Brefeldin A; Cell Compartmentation; Cyclopentanes; Cytoplasmic Granules; Enzyme Precursors; Fluorescent Antibody Technique, Indirect; Glucagon; Golgi Apparatus; Isoenzymes; Mice; Microscopy, Immunoelectron; Molecular Sequence Data; Pancreas; Proprotein Convertase 5; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Serine Endopeptidases; Solubility; Transfection; Tumor Cells, Cultured

1996
Arachidonic acid drives mini-glucagon action in cardiac cells.
    The Journal of biological chemistry, 1997, May-09, Volume: 272, Issue:19

    Topics: 5,8,11,14-Eicosatetraynoic Acid; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Arachidonic Acid; Caffeine; Calcium; Cells, Cultured; Central Nervous System Stimulants; Chick Embryo; Dose-Response Relationship, Drug; Drug Synergism; Electric Stimulation; Glucagon; Homeostasis; Myocardial Contraction; Myocardium; Peptide Fragments; Phospholipases A; Phospholipases A2; Sarcoplasmic Reticulum; Stimulation, Chemical

1997
Glucagon and arginine vasopressin stimulate Mg2+ uptake in mouse distal convoluted tubule cells.
    The American journal of physiology, 1998, Volume: 274, Issue:2

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Arginine Vasopressin; Biological Transport; Cell Line, Transformed; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Glucagon; Kidney Tubules, Distal; Loop of Henle; Magnesium; Mice; Protein Kinase C

1998
Glucagon-mediated Ca2+ signaling in BHK cells expressing cloned human glucagon receptors.
    The American journal of physiology, 1998, Volume: 274, Issue:6

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylate Cyclase Toxin; Animals; Calcium; Cell Line; Cricetinae; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estrenes; Gene Expression; Glucagon; Humans; Kidney; Pertussis Toxin; Pyrrolidinones; Receptors, Glucagon; Receptors, Muscarinic; Recombinant Proteins; Signal Transduction; Type C Phospholipases; Virulence Factors, Bordetella

1998
Glucagon-like peptide-1 does not mediate amylase release from AR42J cells.
    Journal of cellular physiology, 1999, Volume: 181, Issue:3

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amylases; Animals; Base Sequence; Calcium Signaling; Cell Line; Cholecystokinin; Cyclic AMP; DNA Primers; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Pancreas; Peptide Fragments; Phosphorylation; Protein Precursors; Rats; Receptors, Glucagon; Reverse Transcriptase Polymerase Chain Reaction; Tyrosine

1999
Activation of Na(+)- and Ca(2+)-dependent Mg(2+) extrusion by alpha(1)- and beta-adrenergic agonists in rat liver cells.
    American journal of physiology. Gastrointestinal and liver physiology, 2000, Volume: 279, Issue:5

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic Agonists; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adrenergic Uptake Inhibitors; Amiloride; Animals; Calcium; Diuretics; Epinephrine; Glucagon; Glucose; Hepatocytes; Imipramine; Isoproterenol; Liver; Magnesium; Male; Phenylephrine; Phloretin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, beta; Sodium; Stimulation, Chemical

2000
cAMP inhibits inducible nitric oxide synthase expression and NF-kappaB-binding activity in cultured rat hepatocytes.
    The Journal of surgical research, 2001, Volume: 99, Issue:2

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Bucladesine; Cells, Cultured; Colforsin; Cyclic AMP; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Glucagon; Hepatocytes; Interleukin-1; Male; Muscle, Smooth, Vascular; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Promoter Regions, Genetic; Pulmonary Artery; Rats; Rats, Sprague-Dawley; RNA, Messenger; Second Messenger Systems; Sepsis; Transfection

2001
Modulation of glucagon receptor expression and response in transfected human embryonic kidney cells.
    American journal of physiology. Cell physiology, 2001, Volume: 281, Issue:4

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cell Line; Colforsin; Cyclic AMP; Dactinomycin; Enzyme Inhibitors; Gene Expression; Glucagon; GTP-Binding Proteins; Humans; Isoproterenol; Kidney; Protein Synthesis Inhibitors; Rats; Receptors, Glucagon; RNA, Messenger; Sympathomimetics; Transfection

2001
Cell volume affects glycogen phosphorylase activity in fish hepatocytes.
    Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 2003, Volume: 173, Issue:7

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Catfishes; Cell Size; Cyclic AMP; Dextrans; Edetic Acid; Fishes; Glucagon; Glucose; Glycogen Phosphorylase; Hepatocytes; Hypertonic Solutions; Hypotonic Solutions; Liver; Malate Dehydrogenase; Osmolar Concentration; Thionucleotides; Time Factors

2003
Glucagon increases gap junctional intercellular communication via cAMP in the isolated perfused rat liver.
    Shock (Augusta, Ga.), 2004, Volume: 22, Issue:1

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cell Communication; Cyclic AMP; Female; Gap Junctions; Glucagon; Hepatocytes; In Vitro Techniques; Liver; Membrane Potentials; Perfusion; Rats; Rats, Sprague-Dawley

2004
Glucagon and cAMP inhibit cholesterol 7alpha-hydroxylase (CYP7A1) gene expression in human hepatocytes: discordant regulation of bile acid synthesis and gluconeogenesis.
    Hepatology (Baltimore, Md.), 2006, Volume: 43, Issue:1

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adolescent; Bile Acids and Salts; Cells, Cultured; Cholesterol 7-alpha-Hydroxylase; Chromatin; Cyclic AMP-Dependent Protein Kinases; Female; Gene Expression Regulation, Enzymologic; Glucagon; Gluconeogenesis; Hepatocyte Nuclear Factor 4; Hepatocytes; Humans; Male; Middle Aged; Organ Specificity; Phosphorylation; RNA, Messenger; Transcription, Genetic

2006
NR4A orphan nuclear receptors are transcriptional regulators of hepatic glucose metabolism.
    Nature medicine, 2006, Volume: 12, Issue:9

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; DNA-Binding Proteins; Glucagon; Gluconeogenesis; Glucose; Humans; Hyperglycemia; Liver; Male; Mice; Nuclear Receptor Subfamily 4, Group A, Member 1; Nuclear Receptor Subfamily 4, Group A, Member 2; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Transcription Factors

2006
Suppressor of cytokine signaling-3 is a glucagon-inducible inhibitor of PKA activity and gluconeogenic gene expression in hepatocytes.
    The Journal of biological chemistry, 2010, Dec-31, Volume: 285, Issue:53

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Esters; Glucagon; Gluconeogenesis; Hepatocytes; Male; Mice; Mice, Inbred C57BL; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Suppressor of Cytokine Signaling 3 Protein; Suppressor of Cytokine Signaling Proteins

2010
Glucagon stimulates ghrelin secretion through the activation of MAPK and EPAC and potentiates the effect of norepinephrine.
    Endocrinology, 2013, Volume: 154, Issue:2

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium; Caproates; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Drug Synergism; Female; Ghrelin; Glucagon; Guanine Nucleotide Exchange Factors; Male; MAP Kinase Kinase Kinases; Norepinephrine; Rats; Receptors, Glucagon; RNA, Messenger; Stomach

2013
26S Proteasomes are rapidly activated by diverse hormones and physiological states that raise cAMP and cause Rpn6 phosphorylation.
    Proceedings of the National Academy of Sciences of the United States of America, 2019, 03-05, Volume: 116, Issue:10

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Colforsin; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Epinephrine; Glucagon; Hepatocytes; Humans; Kidney; Male; Mice; Muscle, Skeletal; Phosphorylation; Proteasome Endopeptidase Complex; Proteolysis; Proteostasis Deficiencies; Rats; Rats, Sprague-Dawley; Rats, Wistar; Ubiquitinated Proteins

2019