Page last updated: 2024-09-04

glucagon and 2-keto-4-methylvalerate

glucagon has been researched along with 2-keto-4-methylvalerate in 29 studies

Compound Research Comparison

Studies (glucagon)	Trials (glucagon)	Recent Studies (post-2010) (glucagon)	Studies (2-keto-4-methylvalerate)	Trials (2-keto-4-methylvalerate)	Recent Studies (post-2010) (2-keto-4-methylvalerate)
26,039	1,498	3,054	738	52	73

Research

Studies (29)

Timeframe	Studies, this research(%)	All Research%
pre-1990	16 (55.17)	18.7374
1990's	11 (37.93)	18.2507
2000's	2 (6.90)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Gerok, W; Häussinger, D; Lang, F; Morimoto, Y; Stoll, B	1
Biolo, G; Bruttomesso, D; Carlini, M; Duner, E; Fongher, C; Inchiostro, S; Sabadin, L; Tessari, P; Tiengo, A	1
Kuhlman, G; Nissen, S; Roth, JA	1
Bhathena, S; Powell, AM; Recant, L; Solomon, D; Timmers, KI; Voyles, NR; Wilkins, SD	1
Castellino, P; DeFronzo, RA; Luzi, L; Petrides, AS; Simonson, DC	1
Kelly, KJ; Rayfield, EJ	1
Haymond, MW; Miles, JM; Rodriguez, NR; Schwenk, WF	1
Ronner, P; Scarpa, A	1
Haymond, MW; Schwenk, WF	1
Buxton, DB; Hildebrandt, EF; Olson, MS	1
Nissen, S; Ostaszewski, P	2
Biolo, G; Crepaldi, G; Fantin, G; Inchiostro, S; Iori, E; Marescotti, MC; Tessari, P; Tiengo, A; Trevisan, R	1
Abumrad, NN; Cherrington, AD; Jefferson, LS; Lacy, WW; Rannels, SR; Williams, PE	1
Ferguson, DC; Hoenig, M; Matschinsky, FM	1
Grill, V	1
Cambri, S; Di Bernardo, C; Tarantino, G; Vitaglione, R	1
Gwynn, MB; Kilberg, MS	1
Leclercq, R; Leclercq-Meyer, V; Malaisse, WJ; Marchand, J	1
Gerich, JE; Haymond, MW; Miles, JM; Nissen, SL	1
Abumrad, NA; Abumrad, NN; Lacy, WW; Williams, PE; Wise, KL	1
Francini, F; Gagliardino, JJ	1
Martin, F; Sanchez-Andres, JV; Soria, B	1
DeFronzo, RA; Luzi, L; Petrides, AS	1
Ahnefeld, FW; Anhäupl, T; Ensinger, H; Geisser, W; Georgieff, M; Träger, K; Vogt, J	1
Bailey, JW; Haymond, MW; Miles, JM	1
Bolli, GB; Brunetti, P; Cruciani, G; De Feo, P; Lucidi, P; Monacchia, F; Reboldi, G; Volpi, E	1
Bergamini, E; Bombara, M; Fierabracci, V; Masiello, P; Novelli, M; Prentki, M; Vittorini, S	1
Bilz, S; Bloesch, D; Keller, U; Laager, R; Turkalj, I	1

Reviews

1 review(s) available for glucagon and 2-keto-4-methylvalerate

Article	Year
[New trends in the therapy of alcoholic hepatic diseases]. La Clinica terapeutica, 1984, May-15, Volume: 109, Issue:3 Topics: Adrenal Cortex Hormones; Amino Acids; Androgens; Animals; Antithyroid Agents; Colchicine; Enzyme Induction; Glucagon; Hepatitis, Alcoholic; Humans; Insulin; Keto Acids; Liver Cirrhosis, Alcoholic; Liver Diseases, Alcoholic; Medroxyprogesterone; Rats	1984

Trials

1 trial(s) available for glucagon and 2-keto-4-methylvalerate

Article	Year
Effects of medium- and long-chain fatty acids on whole body leucine and glucose kinetics in man. Metabolism: clinical and experimental, 2002, Volume: 51, Issue:6 Topics: Adult; C-Peptide; Carbon Isotopes; Fatty Acids; Fatty Acids, Nonesterified; Glucagon; Glucose; Glucose Clamp Technique; Humans; Hyperinsulinism; Infusions, Intravenous; Insulin; Keto Acids; Lactic Acid; Leucine; Liver; Male; Oxidation-Reduction; Proteins; Reference Values; Triglycerides	2002

Article

Year

Effects of medium- and long-chain fatty acids on whole body leucine and glucose kinetics in man.

Metabolism: clinical and experimental, 2002, Volume: 51, Issue:6

Topics: Adult; C-Peptide; Carbon Isotopes; Fatty Acids; Fatty Acids, Nonesterified; Glucagon; Glucose; Glucose Clamp Technique; Humans; Hyperinsulinism; Infusions, Intravenous; Insulin; Keto Acids; Lactic Acid; Leucine; Liver; Male; Oxidation-Reduction; Proteins; Reference Values; Triglycerides

2002

Other Studies

27 other study(ies) available for glucagon and 2-keto-4-methylvalerate

Article	Year
Anisoosmostic liver perfusion: redox shifts and modulation of alpha-ketoisocaproate and glycine metabolism. Biological chemistry Hoppe-Seyler, 1992, Volume: 373, Issue:8 Topics: Animals; Cell Size; Glucagon; Glutamine; Glycine; Keto Acids; Ketones; Liver; Male; Mitochondria, Liver; NAD; Osmolar Concentration; Osmosis; Oxidation-Reduction; Perfusion; Rats; Rats, Wistar	1992
Effects of insulin and amino acid infusion on leucine and phenylalanine kinetics in type 1 diabetes. The American journal of physiology, 1992, Volume: 262, Issue:2 Pt 1 Topics: Amino Acids; Blood Glucose; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose Clamp Technique; Humans; Infusions, Intravenous; Insulin; Keto Acids; Kinetics; Leucine; Male; Phenylalanine	1992
Effects of alpha-ketoisocaproate on adrenocorticotropin-induced suppression of lymphocyte function in sheep. American journal of veterinary research, 1991, Volume: 52, Issue:3 Topics: Adrenocorticotropic Hormone; Animals; Caproates; CD4-Positive T-Lymphocytes; Female; Glucagon; Hydrocortisone; Immunosuppression Therapy; Insulin; Keto Acids; Lymphocyte Activation; Sheep; T-Lymphocytes; T-Lymphocytes, Regulatory	1991
Multiple alterations in insulin responses to glucose in islets from 48-h glucose-infused nondiabetic rats. Diabetes, 1990, Volume: 39, Issue:11 Topics: Animals; Calcium; Dose-Response Relationship, Drug; Drug Hypersensitivity; Glucagon; Glucose; Glyceraldehyde; Glycerides; Infusions, Intravenous; Insulin; Islets of Langerhans; Keto Acids; Male; Mannoheptulose; Rats; Rats, Inbred Strains; Somatostatin; Temperature; Tetradecanoylphorbol Acetate; Tolbutamide; Verapamil	1990
Leucine metabolism in IDDM. Role of insulin and substrate availability. Diabetes, 1990, Volume: 39, Issue:1 Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Epinephrine; Female; Glucagon; Glucose; Glycated Hemoglobin; Humans; Hydrocortisone; Insulin; Keto Acids; Leucine; Male; Norepinephrine	1990
Virus-induced alterations in cyclic adenosine monophosphate generation in hamster islets of Langerhans. The Journal of clinical investigation, 1986, Volume: 77, Issue:3 Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Cricetinae; Cyclic AMP; Glucagon; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Secretory Rate	1986
Effects of acute metabolic acidosis and alkalosis on leucine metabolism in conscious dogs. Diabetes, 1989, Volume: 38, Issue:7 Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acidosis; Alkalosis; Amino Acids; Animals; Bicarbonates; Blood Gas Analysis; Blood Glucose; Consciousness; Dogs; Fatty Acids, Nonesterified; Glucagon; Hydrochloric Acid; Hydrogen-Ion Concentration; Hydroxybutyrates; Infusions, Intra-Arterial; Insulin; Keto Acids; Leucine; Oxidation-Reduction; Pyruvates; Sodium; Sodium Bicarbonate; Sodium Chloride	1989
Secretagogues for pancreatic hormone release in the channel catfish (Ictalurus punctatus). General and comparative endocrinology, 1987, Volume: 65, Issue:3 Topics: Amino Acids; Animals; Carbohydrates; Catfishes; Fructose; Glucagon; Glucose; Glyceraldehyde; Ictaluridae; Insulin; Insulin Secretion; Keto Acids; Mannose; Pancreas; Pancreatic Hormones; Potassium Chloride; Somatostatin	1987
Effects of leucine, isoleucine, or threonine infusion on leucine metabolism in humans. The American journal of physiology, 1987, Volume: 253, Issue:4 Pt 1 Topics: Analysis of Variance; Breath Tests; C-Peptide; Carbon Dioxide; Demography; Female; Glucagon; Growth Hormone; Humans; Hydrocortisone; Isoleucine; Keto Acids; Leucine; Male; Oxidation-Reduction; Reference Values; Threonine	1987
Acute regulation of the branched-chain 2-oxo acid dehydrogenase complex by adrenaline and glucagon in the perfused rat heart. The Biochemical journal, 1988, Mar-15, Volume: 250, Issue:3 Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Animals; Carbon Dioxide; Epinephrine; Glucagon; Heart; Keto Acids; Ketone Oxidoreductases; Leucine; Male; Multienzyme Complexes; Myocardium; Perfusion; Rats; Rats, Inbred Strains	1988
Effect of hyperglucagonemia on whole-body leucine metabolism in immature pigs before and during a meal. The American journal of physiology, 1988, Volume: 254, Issue:3 Pt 1 Topics: Animals; Blood Glucose; Eating; Fasting; Fatty Acids, Nonesterified; Female; Glucagon; Hydrocortisone; Insulin; Keto Acids; Kinetics; Leucine; Peptide Hydrolases; Swine	1988
Differential effects of hyperinsulinemia and hyperaminoacidemia on leucine-carbon metabolism in vivo. Evidence for distinct mechanisms in regulation of net amino acid deposition. The Journal of clinical investigation, 1987, Volume: 79, Issue:4 Topics: Amino Acids; Blood Glucose; Carbon; Female; Glucagon; Humans; Hyperinsulinism; Insulin; Keto Acids; Kinetics; Leucine; Male	1987
Effects of supplemental dietary energy on leucine metabolism in sheep. The British journal of nutrition, 1985, Volume: 54, Issue:3 Topics: Animals; Energy Intake; Female; Glucagon; Keto Acids; Kinetics; Leucine; Sheep	1985
Role of insulin in the regulation of leucine kinetics in the conscious dog. The Journal of clinical investigation, 1982, Volume: 70, Issue:5 Topics: Animals; Blood Glucose; Dogs; Female; Glucagon; Hindlimb; Insulin; Keto Acids; Kinetics; Leucine; Male; Muscles; Sodium Chloride; Somatostatin	1982
Fuel-induced insulin release in vitro from insulinomas transplanted into the rat kidney. Diabetes, 1984, Volume: 33, Issue:1 Topics: Adenoma, Islet Cell; Animals; Cytochalasin B; Diazoxide; Glucagon; Glucose; Glyceraldehyde; Humans; In Vitro Techniques; Insulin; Insulin Secretion; Insulinoma; Islets of Langerhans; Keto Acids; Kidney; Male; Neoplasm Transplantation; Pancreatic Neoplasms; Radioimmunoassay; Rats; Somatostatin	1984
Nutrient-induced priming of insulin and glucagon secretion. Effects of alpha-ketoisocaproic acid. Endocrinology, 1982, Volume: 110, Issue:3 Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Caproates; Glucagon; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Kinetics; Male; Rats; Rats, Inbred Strains	1982
Plasma membrane transport of 2-ketoisocaproate by rat hepatocytes in primary culture. The Journal of biological chemistry, 1983, Oct-10, Volume: 258, Issue:19 Topics: Animals; Biological Transport; Cell Membrane; Cells, Cultured; Dexamethasone; Diabetes Mellitus, Experimental; Glucagon; Insulin; Keto Acids; Kinetics; Liver; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Sodium	1983
Calcium deprivation enhances glucagon release in the presence of 2-ketoisocaproate. Endocrinology, 1981, Volume: 108, Issue:6 Topics: Animals; Calcium; Chromatography, Gel; Female; Glucagon; Insulin; Keto Acids; Pancreas; Perfusion; Rats	1981
Regulation of alpha-ketoisocaproate binding to albumin in vivo by free fatty acids. The American journal of physiology, 1982, Volume: 242, Issue:1 Topics: Animals; Binding, Competitive; Blood Glucose; Blood Proteins; Caproates; Chromatography, High Pressure Liquid; Dogs; Fatty Acids, Nonesterified; Glucagon; Insulin; Keto Acids; Kinetics; Protein Binding; Serum Albumin; Serum Globulins	1982
Disposal of alpha-ketoisocaproate: roles of liver, gut, and kidneys. The American journal of physiology, 1982, Volume: 243, Issue:2 Topics: Amino Acids, Branched-Chain; Animals; Arteries; Dogs; Female; Glucagon; Insulin; Intestinal Mucosa; Keto Acids; Ketone Bodies; Kidney; Leucine; Liver; Male	1982
An in vitro model suitable for studying insulin secretion in amphibians. General and comparative endocrinology, 1995, Volume: 98, Issue:2 Topics: Acetylcholine; Amphibians; Animals; Arginine; Bufo arenarum; Caproates; Glucagon; Glucose; In Vitro Techniques; Insulin; Insulin Antagonists; Insulin Secretion; Keto Acids; Male; Nifedipine; Pancreatin; Potassium; Radioimmunoassay; Somatostatin; Swine; Tolbutamide	1995
Slow [Ca2+]i oscillations induced by ketoisocaproate in single mouse pancreatic islets. Diabetes, 1995, Volume: 44, Issue:3 Topics: Animals; Bucladesine; Calcium; Caproates; Glucagon; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Kinetics; Mice; Mice, Inbred Strains; Oscillometry; Time Factors	1995
Time-dependent regulation by insulin of leucine metabolism in young healthy adults. The American journal of physiology, 1994, Volume: 267, Issue:3 Pt 1 Topics: Adolescent; Adult; Amino Acids; Blood Glucose; Calorimetry, Indirect; Female; Glucagon; Humans; Hyperinsulinism; Insulin; Keto Acids; Leucine; Male; Osmolar Concentration; Oxidation-Reduction; Reference Values; Time Factors	1994
Glucose and urea production and leucine, ketoisocaproate and alanine fluxes at supraphysiological plasma adrenaline concentrations in volunteers. Intensive care medicine, 1994, Volume: 20, Issue:2 Topics: Adult; Alanine; Amino Acids; Blood Glucose; C-Peptide; Caproates; Critical Illness; Epinephrine; Gas Chromatography-Mass Spectrometry; Glucagon; Gluconeogenesis; Humans; Infusions, Intravenous; Insulin; Keto Acids; Leucine; Liver; Male; Metabolic Clearance Rate; Oxygen Consumption; Proteins; Time Factors; Urea	1994
Effect of parenteral administration of short-chain triglycerides on leucine metabolism. The American journal of clinical nutrition, 1993, Volume: 58, Issue:6 Topics: Analysis of Variance; Animals; Blood Glucose; Dogs; Glucagon; Infusions, Intravenous; Insulin; Keto Acids; Leucine; Oxidation-Reduction; Triacetin	1993
Contribution of amino acids and insulin to protein anabolism during meal absorption. Diabetes, 1996, Volume: 45, Issue:9 Topics: Administration, Oral; Adult; Amino Acids; Antithrombin III; Blood Glucose; C-Peptide; Carbon Radioisotopes; Eating; Fatty Acids, Nonesterified; Female; Fibrinogen; Glucagon; Glucose; Humans; Hyperinsulinism; Immunoglobulin G; Insulin; Intestinal Absorption; Keto Acids; Kinetics; Leucine; Lipid Metabolism; Lipids; Male; Protein Biosynthesis; Proteins; Radioisotope Dilution Technique; Serum Albumin	1996
The antilipolytic agent 3,5-dimethylpyrazole inhibits insulin release in response to both nutrient secretagogues and cyclic adenosine monophosphate agonists in isolated rat islets. Metabolism: clinical and experimental, 2002, Volume: 51, Issue:1 Topics: 1-Methyl-3-isobutylxanthine; Animals; Cyclic AMP; Diglycerides; Glucagon; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Lipolysis; Male; Nutritional Physiological Phenomena; Pyrazoles; Rats; Rats, Sprague-Dawley	2002