glipizide and tolbutamide

glipizide has been researched along with tolbutamide in 69 studies

Research

Studies (69)

Timeframe	Studies, this research(%)	All Research%
pre-1990	28 (40.58)	18.7374
1990's	16 (23.19)	18.2507
2000's	11 (15.94)	29.6817
2010's	13 (18.84)	24.3611
2020's	1 (1.45)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Lombardo, F; Obach, RS; Waters, NJ	1
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Gozalbes, R; Pineda-Lucena, A	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL	1
Melander, A; Wåhlin-Boll, E	2
Balant, L	1
Gotfredsen, CF	1
Garcia, SD; Jarrousse, C; Rosselin, G	1
Hed, R; Nygren, A; Röjdmark, R; Sundblad, L; Wiechel, KL	1
Bandisode, MS; Boshell, BR	1
Müller, WE; Wollert, U	1
Alric, R; Loubatières, AL; Loubatieres-Mariani, MM; Ribes, G; Sorial, G; Tarasco, A	1
Alric, R; Lignon, F; Loubatières, A; Manteghetti, M; Puech, R	1
Aguilar-Bryan, L; Bryan, J; Nelson, DA	1
Harrower, AD	1
Aranyi, Z; Ballagi-Pordány, G; Koltai, MZ; Köszeghy, A; Pogátsa, G	1
Boutagy, JS; Shenfield, GM; Webb, C	1
Dash, RJ; Khandekar, S; Sethi, BK	1
Berbil-Bautista, PR; Felíu, JE; Guijarro, C; López-Alarcón, L; Melián, E	1
Lenzen, S; Männer, K; Panten, U; Trube, G; Zünkler, BJ	1
Wilson, C	1
Felíu, JE; Marcos, ML; Mojena, M; Monge, L	1
Cabello, MA; Felíu, JE; Monge, L; Ortega, JL; Samper, B	1
Ali, L; Hellman, B; Wesslén, N	1
Pollet, RJ; Rogers, BJ; Standaert, ML	1
Boyd, AE; Gaines, KL; Hamilton, S	1
Hellman, B; Sehlin, J; Täljedal, IB	1
Alberetto, M; Baio, G; Bertoletti, A; Pontiroli, AE; Pozza, G	1
Loubatieres-Mariani, MM	1
Melander, A; Sartor, G; Scherstén, B; Wåhlin-Boll, E	2
Brasseur, R; Deleers, M; Gelbcke, M; Malaisse, WJ	1
Fineberg, SE; Schneider, SH	1
Bommartini, F; Emanueli, A; Freddo, J; Pedrazzi, F	1
Groop, L; Tötterman, KJ	1
Fagerlund, C; Gyllenhaal, O; Hartvig, P	1
Arfors, KE; Bergqvist, D; Tangen, O	1
Bachmann, C; Chudziak, F; Löser, S; Panten, U; Schwanstecher, M	1
Elliott, BD; Johnson, R; Langer, O; Prihoda, T; Schenker, S	1
Ammälä, C; Berggren, PO; Bertorello, AM; Bokvist, K; Chibalin, A; Deeney, JT; Eliasson, L; Flatt, PR; Gäbel, J; Gromada, J; Larsson, O; Lindström, P; Renström, E; Rhodes, CJ; Rorsman, P	1
Gross, AS; Rieutord, A; Shenfield, GM; Stupans, I	1
Selvaag, E	1
Bernardi, G; Calabresi, P; Centonze, D; Pisani, A	1
Abenhaim, L; Monette, J; van Staa, T	1
Luo, M; O'Brien, RC	1
Bernardi, G; Federici, M; Guatteo, E; Knöpfel, T; Mercuri, NB; Siniscalchi, A	1
Bataille, D; Blache, P; Gros, L; Salazar, G; Virsolvy, A	1
Brioni, JD; Gopalakrishnan, M; Molinari, EJ; Monteggia, LM; Roch, JM; Scott, VE; Shieh, CC; Sullivan, JP; Whiteaker, KL	1
Galli Kienle, M; Magni, F; Marazzini, L; Monti, L; Pereira, S	1
de Smet, PA; Fischer, HR	1
Argüelles, CF; Granados-Soto, V; Ortiz, MI	1
Andersson, C; Gislason, GH; Hansen, PR; Jørgensen, CH; Køber, L; Mérie, C; Norgaard, ML; Olesen, JB; Schmiegelow, M; Sørensen, R; Torp-Pedersen, C; Vaag, A; Weeke, P	1
Abdelmoneim, AS; Brocks, DR; Hasenbank, SE; Light, PE; Seubert, JM; Simpson, SH	1
Cui, G; McCarty, NA; Song, B; Turki, HW	1
Jung, JS; Kim, CH; Kim, SJ; Kim, SS; Lim, SM; Park, SH; Sim, YB; Suh, HW	1
Andersson, C; Fosbøl, EL; Gislason, G; Køber, L; Mogensen, UM; Scheller, NM; Schramm, TK; Torp-Pedersen, C; Vaag, A	1
Azoulay, L; Douros, A; Filion, KB; Suissa, S; Yin, H; Yu, OHY	1
Jannetto, PJ; Langman, LJ	1

Reviews

4 review(s) available for glipizide and tolbutamide

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
["First" and "second" generation sulfonylureas: distinction or difference? (author's transl)]. Diabete & metabolisme, 1978, Volume: 4, Issue:2 Topics: Animals; Chlorpropamide; Dose-Response Relationship, Drug; Glipizide; Glyburide; Half-Life; Humans; Hypoglycemic Agents; Kinetics; Structure-Activity Relationship; Sulfonylurea Compounds; Tolbutamide	1978
[Timing of administration of sulfonyl urea derivatives]. Nederlands tijdschrift voor geneeskunde, 2000, Jun-17, Volume: 144, Issue:25 Topics: Biological Availability; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Administration Schedule; Gliclazide; Glipizide; Glyburide; Humans; Hypoglycemic Agents; Tolbutamide	2000
Variations in tissue selectivity amongst insulin secretagogues: a systematic review. Diabetes, obesity & metabolism, 2012, Volume: 14, Issue:2 Topics: Animals; ATP-Binding Cassette Transporters; Carbamates; Cardiovascular Diseases; Cricetinae; Cyclohexanes; Diabetes Mellitus, Type 2; Gliclazide; Glipizide; Glyburide; Humans; Hypoglycemic Agents; Ischemic Preconditioning, Myocardial; Isoindoles; Mice; Muscle, Smooth, Vascular; Myocytes, Cardiac; Nateglinide; Phenylalanine; Piperidines; Potassium Channels, Inwardly Rectifying; Rats; Receptors, Drug; Risk Factors; Sulfonylurea Compounds; Sulfonylurea Receptors; Tolbutamide	2012

Trials

6 trial(s) available for glipizide and tolbutamide

Article	Year
Insulin in portal, hepatic and peripheral venous blood after glucose, tolbutamide and glipizide stimulation. Indication of insulin release from peripheral tissues. Acta medica Scandinavica, 1979, Volume: 205, Issue:3 Topics: Adult; Aged; Blood Glucose; Female; Glipizide; Glucose; Hepatic Veins; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Male; Middle Aged; Portal Vein; Sulfonylurea Compounds; Tolbutamide; Veins	1979
Clinical evaluation of a new sulfonylurea in maturity onset diabetes - glipizide (K-4024). Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1976, Volume: 8, Issue:2 Topics: Adult; Aged; Chlorpropamide; Clinical Trials as Topic; Diabetes Mellitus; Dose-Response Relationship, Drug; Drug Evaluation; Drug Therapy, Combination; Follow-Up Studies; Glipizide; Humans; Middle Aged; Phenformin; Sulfonylurea Compounds; Tolbutamide	1976
Efficacy of gliclazide in comparison with other sulphonylureas in the treatment of NIDDM. Diabetes research and clinical practice, 1991, Volume: 14 Suppl 2 Topics: Blood Glucose; Chlorpropamide; Diabetes Mellitus, Type 2; Diet, Diabetic; Gliclazide; Glipizide; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Tolbutamide	1991
Glipizide versus tolbutamide, an open trial. Effects on insulin secretory patterns and glucose concentrations. Diabetologia, 1980, Volume: 18, Issue:1 Topics: Aged; Blood Glucose; Clinical Trials as Topic; Diabetes Mellitus; Fasting; Female; Glipizide; Glucose Tolerance Test; Humans; Insulin; Male; Middle Aged; Placebos; Sulfonylurea Compounds; Tolbutamide	1980
A study of the possible interaction of indoprofen with hypoglycemic sulfonylureas in diabetic patients. European journal of rheumatology and inflammation, 1981, Volume: 4, Issue:1 Topics: Aged; Blood Glucose; Clinical Trials as Topic; Diabetes Complications; Diabetes Mellitus; Double-Blind Method; Drug Interactions; Female; Glipizide; Humans; Hypoglycemic Agents; Indoprofen; Male; Middle Aged; Osteoarthritis; Phenylpropionates; Sulfonylurea Compounds; Tolbutamide	1981
Propranolol does not inhibit sulphonylurea-stimulated insulin secretion in patients with non-insulin dependent diabetes mellitus. Acta endocrinologica, 1982, Volume: 100, Issue:3 Topics: Aged; Blood Glucose; C-Peptide; Clinical Trials as Topic; Diabetes Mellitus; Double-Blind Method; Female; Glipizide; Glucose Tolerance Test; Humans; Insulin; Insulin Secretion; Male; Middle Aged; Propranolol; Random Allocation; Sulfonylurea Compounds; Tolbutamide	1982

Other Studies

59 other study(ies) available for glipizide and tolbutamide

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
First-principle, structure-based prediction of hepatic metabolic clearance values in human. European journal of medicinal chemistry, 2009, Volume: 44, Issue:4 Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software	2009
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
QSAR-based solubility model for drug-like compounds. Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19 Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics. PloS one, 2016, Volume: 11, Issue:10 Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat	2016
High-performance liquid chromatographic determination of glipizide and some other sulfonylurea drugs in serum. Journal of chromatography, 1979, Dec-01, Volume: 164, Issue:4 Topics: Chlorpropamide; Chromatography, High Pressure Liquid; Glipizide; Glyburide; Humans; Hydrogen-Ion Concentration; Sulfonylurea Compounds; Tolbutamide	1979
Dynamics of sulfonylurea-induced insulin release from the isolated perfused rat pancreas. Diabetologia, 1976, Volume: 12, Issue:4 Topics: Animals; Glipizide; Glyburide; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Perfusion; Rats; Sulfonylurea Compounds; Tolbutamide	1976
Biosynthesis of proinsulin and insulin in newborn rat pancreas. Interaction of glucose, cyclic AMP, somatostatin, and sulfonylureas on the (3H) leucine incorporation into immunoreactive insulin. The Journal of clinical investigation, 1976, Volume: 57, Issue:1 Topics: Animals; Animals, Newborn; Antigens; Cyclic AMP; Glipizide; Glucose; Humans; Insulin; Islets of Langerhans; Leucine; Proinsulin; Rats; Somatostatin; Sulfonylurea Compounds; Theophylline; Tolbutamide	1976
Circular dichroism studies on the interaction of sulfonylureas with bovine and human serum albumin. Research communications in chemical pathology and pharmacology, 1976, Volume: 13, Issue:3 Topics: Binding Sites; Binding, Competitive; Carbutamide; Chlorpropamide; Circular Dichroism; Glipizide; Glyburide; Humans; In Vitro Techniques; Optical Rotatory Dispersion; Protein Binding; Serum Albumin; Serum Albumin, Bovine; Sulfonylurea Compounds; Tolbutamide	1976
[Experimental study of glipizide. A comparison with other hypoglycemic sulfonamides (author's transl)]. Diabete & metabolisme, 1975, Volume: 1 Topics: Administration, Oral; Ammonia; Animals; Dogs; Dose-Response Relationship, Drug; Female; Glipizide; Glyburide; Injections, Intravenous; Insulin; Islets of Langerhans; Mice; Purine-Pyrimidine Metabolism, Inborn Errors; Rats; Seizures; Sulfonylurea Compounds; Time Factors; Tolbutamide	1975
[Non-saturable cooperative binding of tolbutamide to rat endocrine pancreas. Criteria of specificity]. Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles, 1976, Jul-19, Volume: 283, Issue:3 Topics: Animals; Diazoxide; Drug Interactions; Glipizide; Glucose; Glyburide; Islets of Langerhans; Kinetics; Rats; Tolbutamide	1976
Specificity of photolabeling of beta-cell membrane proteins with an 125I-labeled glyburide analog. The Journal of biological chemistry, 1992, Jul-25, Volume: 267, Issue:21 Topics: Animals; Binding Sites; Cell Membrane; Chromatography, Gel; Cricetinae; Electrophoresis, Polyacrylamide Gel; Glipizide; Glyburide; Iodine Radioisotopes; Islets of Langerhans; Membrane Proteins; Photochemistry; Substrate Specificity; Tolbutamide; Tumor Cells, Cultured	1992
Divergent cardiac effects of the first and second generation hypoglycemic sulfonylurea compounds. Diabetes research and clinical practice, 1990, Volume: 8, Issue:2 Topics: Animals; Arrhythmias, Cardiac; Blood Glucose; Carbutamide; Dose-Response Relationship, Drug; Electrocardiography; Gliclazide; Glipizide; Glyburide; Hypoglycemic Agents; Male; Myocardial Infarction; Potassium; Rats; Rats, Inbred Strains; Reference Values; Structure-Activity Relationship; Tolbutamide	1990
A screening test for detecting sulfonylureas in plasma. Therapeutic drug monitoring, 1990, Volume: 12, Issue:4 Topics: Aged; Aged, 80 and over; Chlorpropamide; Chromatography, High Pressure Liquid; Female; Gliclazide; Glipizide; Glyburide; Humans; Hypoglycemia; Male; Middle Aged; Sulfonylurea Compounds; Tolbutamide	1990
Effect of sulphonylurea therapy on insulin sensitivity in non insulin dependent diabetics. The Journal of the Association of Physicians of India, 1990, Volume: 38, Issue:7 Topics: Blood Glucose; Diabetes Mellitus, Type 2; Glipizide; Glyburide; Humans; Insulin Resistance; Middle Aged; Sulfonylurea Compounds; Time Factors; Tolbutamide	1990
Modulation of glucose metabolism by sulfonylureas in primary cultures of adult rat hepatocytes. Biochemistry international, 1990, Volume: 21, Issue:6 Topics: Animals; Cells, Cultured; Fructosediphosphates; Glipizide; Glucose; Insulin; Lactates; Liver; Phosphofructokinase-1; Rats; Rats, Inbred Strains; Tolbutamide	1990
Concentration-dependent effects of tolbutamide, meglitinide, glipizide, glibenclamide and diazoxide on ATP-regulated K+ currents in pancreatic B-cells. Naunyn-Schmiedeberg's archives of pharmacology, 1988, Volume: 337, Issue:2 Topics: Adenosine Triphosphate; Animals; Benzamides; Diazoxide; Glipizide; Glyburide; Hypoglycemic Agents; In Vitro Techniques; Ion Channels; Islets of Langerhans; Mice; Mice, Inbred Strains; Potassium; Sulfonylurea Compounds; Tolbutamide	1988
Inhibition by sulphonylureas of vasorelaxation induced by K+ channel activators in vitro. Journal of autonomic pharmacology, 1989, Volume: 9, Issue:1 Topics: Animals; Antihypertensive Agents; Benzopyrans; Cromakalim; Drug Interactions; Glipizide; Glyburide; Guanidines; In Vitro Techniques; Male; Nifedipine; Norepinephrine; Pinacidil; Potassium Channels; Potassium Chloride; Pyrroles; Rabbits; Sulfonylurea Compounds; Tolbutamide; Vasodilator Agents	1989
Effect of sulfonylureas on hepatic glycogen metabolism: activation of glycogen phosphorylase. Metabolism: clinical and experimental, 1989, Volume: 38, Issue:5 Topics: Animals; Cell Separation; Dose-Response Relationship, Drug; Enzyme Activation; Glipizide; Glucose; Glycogen; Liver; Phosphorylases; Rats; Sulfonylurea Compounds; Tolbutamide	1989
Effect of glipizide on hepatic fructose 2,6-bisphosphate concentration and glucose metabolism. Metabolism: clinical and experimental, 1987, Volume: 36, Issue:8 Topics: Animals; Chlorpropamide; Cyclic AMP; Fructosediphosphates; Glipizide; Gluconeogenesis; Glucose; Hexosediphosphates; Hexosephosphates; In Vitro Techniques; Lactates; Liver; Male; Rats; Rats, Inbred Strains; Sulfonylurea Compounds; Tolbutamide	1987
Sulphonamide modulation of sodium content in rat pancreatic islets. European journal of pharmacology, 1988, Dec-13, Volume: 158, Issue:3 Topics: Animals; Calcium; Diazoxide; Glipizide; Glucose; Islets of Langerhans; Male; Potassium; Rats; Rats, Inbred Strains; Sodium; Sulfonamides; Tolbutamide	1988
Direct effects of sulfonylurea agents on glucose transport in the BC3H-1 myocyte. Diabetes, 1987, Volume: 36, Issue:11 Topics: Animals; Cell Line; Deoxy Sugars; Deoxyglucose; Glipizide; Glyburide; Hypoglycemic Agents; Insulin; Kinetics; Mice; Muscles; Tolbutamide	1987
Characterization of the sulfonylurea receptor on beta cell membranes. The Journal of biological chemistry, 1988, Feb-25, Volume: 263, Issue:6 Topics: Animals; ATP-Binding Cassette Transporters; Cell Line; Cell Membrane; Cricetinae; Glipizide; Glyburide; Insulin; Islets of Langerhans; Kinetics; Potassium Channels; Potassium Channels, Inwardly Rectifying; Receptors, Drug; Sulfonylurea Compounds; Sulfonylurea Receptors; Temperature; Tolazamide; Tolbutamide	1988
Glibenclamide is exceptional among hypoglycaemic sulphonylureas in accumulating progressively in beta-cell-rich pancreatic islets. Acta endocrinologica, 1984, Volume: 105, Issue:3 Topics: Animals; Carbutamide; Chlorpropamide; Glipizide; Glyburide; Islets of Langerhans; Mice; Mice, Obese; Sulfonylurea Compounds; Tolbutamide	1984
Sulfonylureas enhance in vivo the effectiveness of insulin in type 1 (insulin dependent) diabetes mellitus. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1984, Volume: 16 Suppl 1 Topics: Adolescent; Adult; Chlorpropamide; Diabetes Mellitus, Type 1; Drug Interactions; Female; Glipizide; Humans; Insulin; Male; Sulfonylurea Compounds; Tolbutamide	1984
Clinical pharmacology of glipizide. The American journal of medicine, 1983, Nov-30, Volume: 75, Issue:5B Topics: Biological Availability; Blood Glucose; Chlorpropamide; Diabetes Mellitus, Type 2; Glipizide; Glyburide; Half-Life; Humans; Kinetics; Structure-Activity Relationship; Sulfonylurea Compounds; Tolbutamide	1983
Glipizide: experimental study and comparison with other sulfonylureas. Acta endocrinologica. Supplementum, 1980, Volume: 239 Topics: Animals; Blood Glucose; Dogs; Dose-Response Relationship, Drug; Glipizide; Glyburide; Hypoglycemia; Insulin; Islets of Langerhans; Mice; Rats; Sulfonylurea Compounds; Tolbutamide	1980
Kinetics-effect relations of glipizide and other sulfonylureas. Acta endocrinologica. Supplementum, 1980, Volume: 239 Topics: Blood Glucose; Chlorpropamide; Diabetes Mellitus; Dose-Response Relationship, Drug; Fasting; Feeding Behavior; Glipizide; Glyburide; Humans; Kidney; Sulfonylurea Compounds; Tolbutamide	1980
Comparative single-dose kinetics and effects of four sulfonylureas in healthy volunteers. Acta medica Scandinavica, 1980, Volume: 208, Issue:4 Topics: Adult; Blood Glucose; Chlorpropamide; Fasting; Glipizide; Glyburide; Humans; Insulin; Kinetics; Male; Sulfonylurea Compounds; Time Factors; Tolbutamide	1980
Homologous and hybrid calcium complexes of A23187 and hypoglycemic sulfonylureas: nuclear magnetic resonance and conformational analysis. Journal of inorganic biochemistry, 1982, Volume: 16, Issue:3 Topics: Anti-Bacterial Agents; Calcimycin; Calcium; Chemical Phenomena; Chemistry; Gliclazide; Glipizide; Magnetic Resonance Spectroscopy; Molecular Conformation; Sulfonylurea Compounds; Tolbutamide	1982
Electron-capture gas chromatography of plasma sulphonylureas after extractive methylation. Journal of chromatography, 1980, Jan-11, Volume: 181, Issue:1 Topics: Chromatography, Gas; Gas Chromatography-Mass Spectrometry; Glipizide; Humans; Sulfonylurea Compounds; Tolbutamide	1980
Effects of gliclazide--a new antidiabetic agent--on blood platelet function in vitro and in vivo. Upsala journal of medical sciences, 1980, Volume: 85, Issue:1 Topics: Adenosine Diphosphate; Animals; Collagen; Female; Gliclazide; Glipizide; Hemostasis; Humans; In Vitro Techniques; Lasers; Male; Microcirculation; Platelet Aggregation; Rabbits; Sulfonylurea Compounds; Tolbutamide	1980
Photoaffinity labeling of the cerebral sulfonylurea receptor using a novel radioiodinated azidoglibenclamide analogue. Journal of neurochemistry, 1994, Volume: 63, Issue:2 Topics: Affinity Labels; Animals; ATP-Binding Cassette Transporters; Binding, Competitive; Cell Fractionation; Cerebral Cortex; Electrophoresis, Polyacrylamide Gel; Glipizide; Glyburide; Iodine Radioisotopes; Kinetics; Microsomes; Molecular Weight; Photolysis; Potassium Channels; Potassium Channels, Inwardly Rectifying; Radioligand Assay; Receptors, Drug; Sulfonylurea Receptors; Swine; Tolbutamide; Tritium	1994
Comparative placental transport of oral hypoglycemic agents in humans: a model of human placental drug transfer. American journal of obstetrics and gynecology, 1994, Volume: 171, Issue:3 Topics: Administration, Oral; Analysis of Variance; Antipyrine; Biological Transport; Chlorpropamide; Chromatography, High Pressure Liquid; Female; Glipizide; Glyburide; Humans; Hypoglycemic Agents; Maternal-Fetal Exchange; Models, Biological; Molecular Weight; Placenta; Pregnancy; Regression Analysis; Tolbutamide	1994
PKC-dependent stimulation of exocytosis by sulfonylureas in pancreatic beta cells. Science (New York, N.Y.), 1996, Feb-09, Volume: 271, Issue:5250 Topics: Animals; Calcium; Cells, Cultured; Cytoplasmic Granules; Electric Conductivity; Exocytosis; Glipizide; Glyburide; Hypoglycemic Agents; Insulin; Insulin Secretion; Islets of Langerhans; Membrane Potentials; Mice; Patch-Clamp Techniques; Protein Kinase C; Sulfonylurea Compounds; Tolbutamide	1996
Gliclazide hydroxylation by rat liver microsomes. Xenobiotica; the fate of foreign compounds in biological systems, 1995, Volume: 25, Issue:12 Topics: Animals; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Gliclazide; Glipizide; Glyburide; Hydroxylation; Hypoglycemic Agents; Kinetics; Male; Microsomes, Liver; Mixed Function Oxygenases; Rats; Rats, Sprague-Dawley; Tolbutamide	1995
Photohemolytic potency of oral antidiabetic drugs in vitro: effects of antioxidants and a nitrogen atmosphere. Photodermatology, photoimmunology & photomedicine, 1996, Volume: 12, Issue:4 Topics: Antioxidants; Ascorbic Acid; Carbutamide; Chlorpropamide; Dose-Response Relationship, Drug; Gliclazide; Glipizide; Glyburide; Hemolysis; Humans; Hypoglycemic Agents; Nitrogen; Radiation-Sensitizing Agents; Reactive Oxygen Species; Sulfonamides; Sulfonylurea Compounds; Superoxide Dismutase; Tolazamide; Tolbutamide; Ultraviolet Rays; Vitamin E	1996
Endogenous adenosine mediates the presynaptic inhibition induced by aglycemia at corticostriatal synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1997, Jun-15, Volume: 17, Issue:12 Topics: Adenosine; Animals; Caffeine; Cerebral Cortex; Corpus Striatum; Evoked Potentials; Glipizide; Glucose; Glutamic Acid; Hypoglycemic Agents; In Vitro Techniques; Membrane Potentials; Neurons; Potassium Channel Blockers; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Synapses; Theophylline; Tolbutamide; Xanthines	1997
Rates of hypoglycemia in users of sulfonylureas. Journal of clinical epidemiology, 1997, Volume: 50, Issue:6 Topics: Adult; Aged; Chlorpropamide; Female; Gliclazide; Glipizide; Glyburide; Humans; Hypoglycemia; Hypoglycemic Agents; Incidence; Male; Middle Aged; Poisson Distribution; Risk; Risk Factors; Sulfonylurea Compounds; Surveys and Questionnaires; Time Factors; Tolbutamide	1997
The effects of gliclazide and other sulfonylureas on low-density lipoprotein oxidation in vitro. Metabolism: clinical and experimental, 1997, Volume: 46, Issue:12 Suppl 1 Topics: Administration, Oral; Adult; Antioxidants; Ascorbic Acid; Coronary Artery Disease; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Gliclazide; Glipizide; Glyburide; Humans; Hypoglycemic Agents; Lipoproteins, LDL; Male; Middle Aged; Oxidation-Reduction; Sulfonylurea Compounds; Tolbutamide	1997
Whole cell patch-clamp recordings of rat midbrain dopaminergic neurons isolate a sulphonylurea- and ATP-sensitive component of potassium currents activated by hypoxia. Journal of neurophysiology, 1998, Volume: 79, Issue:3 Topics: Adenosine Triphosphate; Animals; Barium Compounds; Cell Hypoxia; Charybdotoxin; Chlorides; Dopamine; Glipizide; Glyburide; In Vitro Techniques; Membrane Potentials; Mesencephalon; Microelectrodes; Neurons; Patch-Clamp Techniques; Potassium Channels; Rats; Rats, Wistar; Reaction Time; Sulfonylurea Compounds; Tolbutamide	1998
Characterization of low-affinity binding sites for glibenclamide on the Kir6.2 subunit of the beta-cell KATP channel. Biochemical and biophysical research communications, 1999, Apr-21, Volume: 257, Issue:3 Topics: Animals; ATP-Binding Cassette Transporters; Binding Sites; Blotting, Northern; Cell Line; Cell Membrane; COS Cells; Gliclazide; Glipizide; Glyburide; Islets of Langerhans; Kinetics; Organelles; Phentolamine; Potassium Channels; Potassium Channels, Inwardly Rectifying; Rats; Receptors, Drug; Recombinant Fusion Proteins; Sulfonylurea Compounds; Sulfonylurea Receptors; Tolbutamide; Transfection	1999
Pharmacology of human sulphonylurea receptor SUR1 and inward rectifier K(+) channel Kir6.2 combination expressed in HEK-293 cells. British journal of pharmacology, 2000, Volume: 129, Issue:7 Topics: ATP-Binding Cassette Transporters; Binding, Competitive; Cations; Cell Line; Deoxyglucose; Diazoxide; Dose-Response Relationship, Drug; Electric Stimulation; Electrophysiology; Fluorescence; Gene Expression; Glipizide; Glyburide; Humans; Membrane Potentials; Oligomycins; Potassium Channels; Potassium Channels, Inwardly Rectifying; Radioligand Assay; Receptors, Drug; Recombinant Fusion Proteins; RNA, Messenger; Sulfonylurea Compounds; Sulfonylurea Receptors; Tolazamide; Tolbutamide; Tritium	2000
Identification of sulfonylureas in serum by electrospray mass spectrometry. Analytical biochemistry, 2000, Jun-15, Volume: 282, Issue:1 Topics: Calibration; Chlorpropamide; Chromatography, Liquid; Glipizide; Glyburide; Humans; Mass Spectrometry; Models, Chemical; Sulfonylurea Compounds; Tolbutamide; Ultraviolet Rays	2000
The peripheral antinociceptive effect of resveratrol is associated with activation of potassium channels. Neuropharmacology, 2002, Volume: 43, Issue:5 Topics: 4-Aminopyridine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apamin; ATP-Binding Cassette Transporters; Charybdotoxin; Female; Glipizide; Glyburide; KATP Channels; Morphine; Narcotics; Peripheral Nervous System; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Calcium-Activated; Potassium Channels, Inwardly Rectifying; Rats; Rats, Wistar; Resveratrol; Stilbenes; Tetraethylammonium; Tolbutamide	2002
Comparable long-term mortality risk associated with individual sulfonylureas in diabetes patients with heart failure. Diabetes research and clinical practice, 2011, Volume: 94, Issue:1 Topics: Aged; Aged, 80 and over; Diabetes Mellitus; Female; Glipizide; Glyburide; Heart Failure; Humans; Hypoglycemic Agents; Male; Sulfonylurea Compounds; Tolbutamide	2011
Differential contribution of TM6 and TM12 to the pore of CFTR identified by three sulfonylurea-based blockers. Pflugers Archiv : European journal of physiology, 2012, Volume: 463, Issue:3 Topics: Alanine; Amino Acid Sequence; Animals; Benzamides; Cystic Fibrosis Transmembrane Conductance Regulator; Glipizide; Glyburide; Ion Channel Gating; Kinetics; Mutagenesis; Oocytes; Patch-Clamp Techniques; Sulfonylurea Compounds; Tolbutamide; Xenopus	2012
Effect of tolbutamide, glyburide and glipizide administered supraspinally on CA3 hippocampal neuronal cell death and hyperglycemia induced by kainic acid in mice. Brain research, 2014, May-20, Volume: 1564 Topics: Animals; Blood Glucose; CA3 Region, Hippocampal; Cell Death; Glipizide; Glyburide; Hyperglycemia; Hypoglycemic Agents; Infusions, Intraventricular; Kainic Acid; Male; Mice; Mice, Inbred ICR; Neurons; Sulfonylurea Compounds; Tolbutamide	2014
Metformin in combination with various insulin secretagogues in type 2 diabetes and associated risk of cardiovascular morbidity and mortality--a retrospective nationwide study. Diabetes research and clinical practice, 2015, Volume: 107, Issue:1 Topics: Aged; Carbamates; Cardiovascular Diseases; Denmark; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Gliclazide; Glipizide; Glyburide; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Morbidity; Myocardial Infarction; Piperidines; Registries; Retrospective Studies; Risk Factors; Stroke; Sulfonylurea Compounds; Tolbutamide	2015
Pharmacologic Differences of Sulfonylureas and the Risk of Adverse Cardiovascular and Hypoglycemic Events. Diabetes care, 2017, Volume: 40, Issue:11 Topics: Aged; Aged, 80 and over; Body Mass Index; Cardiovascular Diseases; Cohort Studies; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Gliclazide; Glipizide; Glycated Hemoglobin; Humans; Hypoglycemia; Hypoglycemic Agents; Incidence; Male; Middle Aged; Myocardial Infarction; Pancreas; Proportional Hazards Models; Risk Factors; Stroke; Sulfonylurea Compounds; Tolbutamide; United Kingdom	2017
Analysis of Hypoglycemic Drugs by Liquid Chromatography-Tandem Mass Spectrometry. Methods in molecular biology (Clifton, N.J.), 2024, Volume: 2737 Topics: Chlorpropamide; Chromatography, High Pressure Liquid; Chromatography, Liquid; Glipizide; Glyburide; Humans; Hypoglycemic Agents; Nateglinide; Pioglitazone; Rosiglitazone; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Tolazamide; Tolbutamide	2024