Compounds > gliclazide

gliclazide and arginine

gliclazide has been researched along with arginine in 15 studies

Research

Studies (15)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (13.33)	18.7374
1990's	5 (33.33)	18.2507
2000's	2 (13.33)	29.6817
2010's	5 (33.33)	24.3611
2020's	1 (6.67)	2.80

Authors

Authors	Studies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Borghi, VC; Giannella-Neto, D; Porrelli, RN; Santomauro, AT; Wajchenberg, BL	1
Hisatomi, A; Inoue, K; Nawata, H; Umeda, F	1
Bailbé, D; Portha, B; Serradas, P	1
Brogard, JM; Dorner, M; Pinget, M	1
Hara, M; Sasaki, H; Takahashi, K; Yamatani, K	1
Barrow, BA; Levy, JC; Manley, SE; Rachman, J; Turner, RC	1
Boland, O; Matthews, DR	1
Cassone-Faldetta, M; De Luca, O; De Mattia, G; Fava, D; Ghiselli, A; Laurenti, O	1
Cejvan, K; Cerasi, E; Coy, DH; Efendic, S; Holst, JJ	1
Eggert, F; Elgert, C; Früh, E; Rustenbeck, I; Scherneck, S	1
Geddawy, A; Imamura, T; Okamura, T; Shimosato, T; Tawa, M	1
He, X; Ji, Y; Lei, T; Liu, Q; Tian, W; Wang, G; Wang, Y; Xu, H; Zhao, D	1

Trials

3 trial(s) available for gliclazide and arginine

Article	Year
Relative hyperproinsulinemia of NIDDM persists despite the reduction of hyperglycemia with insulin or sulfonylurea therapy. Diabetes, 1997, Volume: 46, Issue:10 Topics: Adult; Aged; Arginine; Blood Glucose; C-Peptide; Cross-Over Studies; Diabetes Mellitus, Type 2; Fasting; Gliclazide; Glucose Clamp Technique; Humans; Hypoglycemic Agents; Insulin; Middle Aged; Proinsulin	1997
The stimulation of insulin secretion in non-insulin-dependent diabetic patients by amino acids and gliclazide in the basal and hyperglycemic state. Metabolism: clinical and experimental, 1997, Volume: 46, Issue:12 Suppl 1 Topics: Aged; Arginine; Blood Glucose; C-Peptide; Cross-Over Studies; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Double-Blind Method; Drug Synergism; Female; Gliclazide; Glucose Clamp Technique; Humans; Hyperglycemia; Hypoglycemic Agents; Infusions, Intravenous; Insulin; Insulin Secretion; Leucine; Male; Middle Aged; Time Factors	1997
Gliclazide improves anti-oxidant status and nitric oxide-mediated vasodilation in Type 2 diabetes. Diabetic medicine : a journal of the British Diabetic Association, 2002, Volume: 19, Issue:9 Topics: Adult; Aged; Antioxidants; Arginine; Blood Pressure; Diabetes Mellitus, Type 2; Free Radicals; Gliclazide; Glyburide; Humans; Hypoglycemic Agents; Injections, Intravenous; Lipid Peroxides; Male; Middle Aged; Nitric Oxide; Oxidative Stress; Vasodilation	2002

Other Studies

12 other study(ies) available for gliclazide and arginine

Article	Year
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Short- and long-term gliclazide effects on pancreatic islet cell function and hepatic insulin extraction in non-insulin-dependent diabetes mellitus. Diabetes research and clinical practice, 1992, Volume: 17, Issue:2 Topics: Administration, Oral; Adult; Arginine; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Gliclazide; Glucose; Glucose Tolerance Test; Humans; Injections, Intravenous; Insulin; Islets of Langerhans; Liver; Male; Middle Aged; Sulfonylurea Compounds; Time Factors	1992
Release of amylin from perfused rat pancreas in response to glucose, arginine, beta-hydroxybutyrate, and gliclazide. Diabetes, 1991, Volume: 40, Issue:8 Topics: 3-Hydroxybutyric Acid; Amyloid; Animals; Arginine; Gliclazide; Glucose; Hydroxybutyrates; In Vitro Techniques; Insulin; Insulin Secretion; Islet Amyloid Polypeptide; Islets of Langerhans; Kinetics; Male; Perfusion; Rats; Rats, Inbred Strains; Time Factors	1991
Long-term gliclazide treatment improves the in vitro glucose-induced insulin release in rats with type 2 (non-insulin-dependent) diabetes induced by neonatal streptozotocin. Diabetologia, 1989, Volume: 32, Issue:8 Topics: Animals; Animals, Newborn; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Gliclazide; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Rats; Rats, Inbred Strains; Reference Values; Streptozocin; Sulfonylurea Compounds	1989
Effect of middle-term gliclazide treatment on insulin secretion in non-insulin dependent diabetics. Current medical research and opinion, 1984, Volume: 9, Issue:1 Topics: Adult; Arginine; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Female; Gliclazide; Glucagon; Glucose Tolerance Test; Humans; Insulin; Insulin Secretion; Iodine Radioisotopes; Male; Middle Aged; Sulfonylurea Compounds; Time Factors	1984
Gliclazide directly suppresses arginine-induced glucagon secretion. Diabetes research and clinical practice, 1994, Volume: 24, Issue:3 Topics: Animals; Arginine; Cysteamine; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Drug Interactions; Gliclazide; Glucagon; Insulin; Insulin Secretion; Male; Pancreas; Rats; Rats, Wistar; Somatostatin; Streptozocin; Sulfonylurea Compounds	1994
Gliclazide directly inhibits arginine-induced glucagon release. Diabetes, 2002, Volume: 51 Suppl 3 Topics: Animals; Arginine; Gliclazide; Glucagon; In Vitro Techniques; Islets of Langerhans; Male; Pancreas; Peptides, Cyclic; Rats; Rats, Wistar; Receptors, Somatostatin; Somatostatin; Sulfonylurea Compounds	2002
Glucagonotropic and Glucagonostatic Effects of KATP Channel Closure and Potassium Depolarization. Endocrinology, 2021, 01-01, Volume: 162, Issue:1 Topics: Animals; Arginine; Calcium; Cell Membrane; Female; Gliclazide; Glucagon; Glucagon-Secreting Cells; Glucose; Hypoglycemic Agents; Insulin; Insulin Secretion; Insulin-Secreting Cells; KATP Channels; Membrane Potentials; Mice; Potassium; Potassium Chloride; Tolbutamide	2021
Mechanism underlying endothelium-dependent relaxation by 2-methylthio-ADP in monkey cerebral artery. Journal of pharmacological sciences, 2010, Volume: 114, Issue:2 Topics: Adenosine Diphosphate; Animals; Apamin; Arachidonic Acids; Arginine; Biological Factors; Cerebral Arteries; Charybdotoxin; Dose-Response Relationship, Drug; Drug Synergism; Endothelium, Vascular; Female; Glycyrrhetinic Acid; Macaca; Male; Nitric Oxide; Nitroprusside; Thionucleotides; Vasodilation	2010
Effect of 18β-glycyrrhetinic acid on cerebral vasospasm caused by asymmetric dimethylarginine after experimental subarachnoid hemorrhage in rats. Neurological research, 2015, Volume: 37, Issue:6 Topics: Animals; Arginine; Basilar Artery; Blotting, Western; Connexin 43; Connexins; Disease Models, Animal; Glycyrrhetinic Acid; Neuroprotective Agents; Random Allocation; Rats, Sprague-Dawley; Severity of Illness Index; Subarachnoid Hemorrhage; Time Factors; Vasospasm, Intracranial	2015