Compounds > glabridin
Page last updated: 2024-09-03

glabridin and tamoxifen

glabridin has been researched along with tamoxifen in 4 studies

Compound Research Comparison

Studies
(glabridin)		Trials
(glabridin)		Recent Studies (post-2010)
(glabridin)		Studies
(tamoxifen)		Trials
(tamoxifen)		Recent Studies (post-2010) (tamoxifen)
172412220,6302,2276,256

Protein Interaction Comparison

ProteinTaxonomyglabridin (IC50)tamoxifen (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.46
Serine/threonine-protein kinase D3Homo sapiens (human)1
Bile salt export pumpHomo sapiens (human)10
Epidermal growth factor receptorHomo sapiens (human)3.553
Estrogen receptorHomo sapiens (human)0.9266
Receptor tyrosine-protein kinase erbB-2Homo sapiens (human)2.949
Protein kinase C gamma typeHomo sapiens (human)1
Protein kinase C beta typeHomo sapiens (human)1
Tyrosine-protein kinase LckHomo sapiens (human)8.033
Tyrosine-protein kinase FynHomo sapiens (human)1.195
Progesterone receptorHomo sapiens (human)0.1288
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)1.472
Muscarinic acetylcholine receptor M2Homo sapiens (human)7.793
Muscarinic acetylcholine receptor M4Homo sapiens (human)4.817
ATP-dependent translocase ABCB1Homo sapiens (human)6.4
Muscarinic acetylcholine receptor M5Homo sapiens (human)2.585
Alpha-2A adrenergic receptorHomo sapiens (human)1.935
Adenosine receptor A3Homo sapiens (human)3.701
Muscarinic acetylcholine receptor M1Homo sapiens (human)2.829
Steroid hormone receptor ERR1Homo sapiens (human)0.2
Angiotensin-converting enzymeOryctolagus cuniculus (rabbit)0.967
Beta-3 adrenergic receptorHomo sapiens (human)7.703
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)3.701
Protein kinase C alpha typeHomo sapiens (human)1
Alpha-2B adrenergic receptorHomo sapiens (human)3.518
Muscarinic acetylcholine receptor M3Homo sapiens (human)2.974
Substance-K receptorHomo sapiens (human)3.67
D(1A) dopamine receptorHomo sapiens (human)8.502
Prostaglandin G/H synthase 1Homo sapiens (human)4.391
Sodium-dependent noradrenaline transporter Homo sapiens (human)1.472
Thromboxane-A synthase Homo sapiens (human)0.916
Protein kinase C eta typeHomo sapiens (human)1
Histamine H2 receptorHomo sapiens (human)9.396
Alpha-1D adrenergic receptorHomo sapiens (human)4.982
5-hydroxytryptamine receptor 2AHomo sapiens (human)4.801
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.46
Adenosine receptor A2aHomo sapiens (human)7.099
Sodium-dependent serotonin transporterHomo sapiens (human)2.334
D(3) dopamine receptorHomo sapiens (human)1.072
5-hydroxytryptamine receptor 2BHomo sapiens (human)2.084
Protein kinase C iota typeHomo sapiens (human)1
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)3.701
5-hydroxytryptamine receptor 6Homo sapiens (human)2.679
Estrogen-related receptor gammaHomo sapiens (human)0.0622
Sodium-dependent dopamine transporter Homo sapiens (human)1.841
Protein kinase C epsilon typeHomo sapiens (human)1
Protein kinase C theta typeHomo sapiens (human)1
Protein kinase C zeta typeHomo sapiens (human)1
Protein kinase C delta typeHomo sapiens (human)1
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)1.2759
Platelet-activating factor acetylhydrolaseHomo sapiens (human)0.904
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomeraseHomo sapiens (human)0.012
Serine/threonine-protein kinase D1Homo sapiens (human)1
Nuclear receptor subfamily 3 group C member 3 Bos taurus (cattle)0.967
Estrogen receptor betaHomo sapiens (human)0.7809
Sigma non-opioid intracellular receptor 1Homo sapiens (human)0.021
7-dehydrocholesterol reductaseHomo sapiens (human)0.012

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (75.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dansette, PM; Fontana, E; Poli, SM1
Eizenberg, M; Kaye, A; Shelach, R; Somjen, D; Stern, N; Tamir, S; Vaya, J1
Eizenberg, M; Izrael, S; Somjen, D; Tamir, S; Vaya, J1
Jen, SH; Wei, MP; Yin, AC1

Reviews

1 review(s) available for glabridin and tamoxifen

ArticleYear
Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity.
    Current drug metabolism, 2005, Volume: 6, Issue:5

    Topics: Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Humans; Isoenzymes; Structure-Activity Relationship; Terminology as Topic

2005

Other Studies

3 other study(ies) available for glabridin and tamoxifen

ArticleYear
Estrogenic and antiproliferative properties of glabridin from licorice in human breast cancer cells.
    Cancer research, 2000, Oct-15, Volume: 60, Issue:20

    Topics: Animals; Binding, Competitive; Breast Neoplasms; Cell Adhesion; Cell Division; Creatine Kinase; Drug Interactions; Estradiol; Estrogen Receptor Modulators; Estrogens, Non-Steroidal; Female; Humans; Isoflavones; Molecular Mimicry; Organ Specificity; Phenols; Plant Extracts; Rats; Rats, Wistar; Receptors, Estrogen; Structure-Activity Relationship; Tamoxifen; Tumor Cells, Cultured

2000
Estrogen-like activity of glabrene and other constituents isolated from licorice root.
    The Journal of steroid biochemistry and molecular biology, 2001, Volume: 78, Issue:3

    Topics: Animals; Breast Neoplasms; Cell Division; Estradiol; Estrogen Receptor Modulators; Estrogens, Non-Steroidal; Female; Glycyrrhiza; HeLa Cells; Humans; Isoflavones; Organ Specificity; Phenols; Phytoestrogens; Phytotherapy; Plant Preparations; Rats; Rats, Wistar; Receptors, Estrogen; Tamoxifen; Transcription, Genetic; Tumor Cells, Cultured

2001
The Combinatory Effects of Glabridin and Tamoxifen on Ishikawa and MCF-7 Cell Lines.
    Natural product communications, 2015, Volume: 10, Issue:9

    Topics: Adenocarcinoma; Breast Neoplasms; Cell Line, Tumor; Drug Therapy, Combination; Endometrial Neoplasms; Estrogens; Female; Humans; Isoflavones; Phenols; Phytoestrogens; Selective Estrogen Receptor Modulators; Tamoxifen

2015