Page last updated: 2024-09-03

glabridin and isoliquiritigenin

glabridin has been researched along with isoliquiritigenin in 9 studies

Compound Research Comparison

Studies
(glabridin)
Trials
(glabridin)
Recent Studies (post-2010)
(glabridin)
Studies
(isoliquiritigenin)
Trials
(isoliquiritigenin)
Recent Studies (post-2010) (isoliquiritigenin)
17241224722324

Protein Interaction Comparison

ProteinTaxonomyglabridin (IC50)isoliquiritigenin (IC50)
Estrogen receptorHomo sapiens (human)1.87
Interstitial collagenaseHomo sapiens (human)0.016
Cytochrome P450 1A2Homo sapiens (human)0.269
72 kDa type IV collagenaseHomo sapiens (human)0.01
Stromelysin-1Homo sapiens (human)0.081
Cytochrome P450 3A4Homo sapiens (human)0.269
MatrilysinHomo sapiens (human)0.008
Cytochrome P450 2D6Homo sapiens (human)0.269
AromataseHomo sapiens (human)3.8
17-beta-hydroxysteroid dehydrogenase type 1Homo sapiens (human)2.83
Matrix metalloproteinase-9Homo sapiens (human)0.01
Aldo-keto reductase family 1 member B1Homo sapiens (human)0.32
Proteasome subunit beta type-5Homo sapiens (human)4.88
17-beta-hydroxysteroid dehydrogenase type 2Homo sapiens (human)0.36
Collagenase 3Homo sapiens (human)0.014
Estrogen receptor betaHomo sapiens (human)0.269
NACHT, LRR and PYD domains-containing protein 3 Homo sapiens (human)1.54

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (11.11)29.6817
2010's7 (77.78)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Ji, S; Li, K; Li, Z; Liang, W; Qiao, X; Song, W; Tang, S; Wang, Q; Wang, Y; Ye, M; Yu, S; Zhou, D1
Cui, Z; Ji, S; Kuang, Y; Li, K; Lin, Y; Qiao, X; Song, W; Tang, S; Ye, M; Yu, S1
Kuang, Y; Li, K; Lin, Y; Qiao, X; Sabir, G; Song, W; Wang, S; Ye, M1
Chen, K; Ji, S; Kuang, Y; Li, K; Lin, Y; Qiao, X; Song, W; Wang, S; Ye, M1
Fan, J; Kuang, Y; Li, B; Qiao, X; Ye, M1
Ben-Arie, R; Izrael, S; Musa, R; Nerya, O; Tamir, S; Vaya, J1
Agarwal, A; Chandrasekaran, CV; Deepak, HB; Deepak, M; Kathiresan, S; Sangli, GK; Thiyagarajan, P1
Agarwal, A; Chandrasekaran, CV; Deepak, HB; Thiyagarajan, P1
Chen, XY; Cui, WQ; Hao, JY; Li, YH; Liu, YY; Wang, TT; Wang, XZ; Wu, T; Xing, C; Yuan, SG; Zhang, Y; Zhang, ZY; Zheng, SD; Zou, XS1

Other Studies

9 other study(ies) available for glabridin and isoliquiritigenin

ArticleYear
Bioactive Constituents of Glycyrrhiza uralensis (Licorice): Discovery of the Effective Components of a Traditional Herbal Medicine.
    Journal of natural products, 2016, Feb-26, Volume: 79, Issue:2

    Topics: Acetylcholinesterase; Animals; Carbon Tetrachloride; Drugs, Chinese Herbal; Glycyrrhiza; Glycyrrhiza uralensis; GPI-Linked Proteins; Hep G2 Cells; Humans; Influenza A Virus, H1N1 Subtype; Lipopolysaccharides; Liver; Macrophages; MCF-7 Cells; Medicine, Traditional; Mice; Molecular Structure; Monophenol Monooxygenase; NF-kappa B; Nitric Oxide; Nuclear Magnetic Resonance, Biomolecular; Plant Roots; Plants, Medicinal; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Pyrrolizidine Alkaloids; Rhizome; Structure-Activity Relationship

2016
Glycybridins A-K, Bioactive Phenolic Compounds from Glycyrrhiza glabra.
    Journal of natural products, 2017, 02-24, Volume: 80, Issue:2

    Topics: Animals; Antioxidants; Drug Screening Assays, Antitumor; Glycyrrhiza; Hep G2 Cells; Humans; Lipopolysaccharides; Macrophages; Mice; Molecular Structure; Monophenol Monooxygenase; NF-kappa B; Nitric Oxide; Phenols; Plant Roots; Plants, Medicinal; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Rhizome

2017
Screening for bioactive natural products from a 67-compound library of Glycyrrhiza inflata.
    Bioorganic & medicinal chemistry, 2017, 07-15, Volume: 25, Issue:14

    Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Biological Products; Cell Line, Tumor; Drug Screening Assays, Antitumor; Glycyrrhiza; HEK293 Cells; Hep G2 Cells; Humans; Lipopolysaccharides; Macrophages; MCF-7 Cells; Mice; Monophenol Monooxygenase; NF-kappa B; Plant Roots; Protein Tyrosine Phosphatase, Non-Receptor Type 1; RAW 264.7 Cells; Small Molecule Libraries

2017
Nrf2 activators from Glycyrrhiza inflata and their hepatoprotective activities against CCl
    Bioorganic & medicinal chemistry, 2017, 10-15, Volume: 25, Issue:20

    Topics: Administration, Oral; Animals; Carbon Tetrachloride; Cell Survival; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Dose-Response Relationship, Drug; Glycyrrhiza; Hep G2 Cells; Humans; Male; Mice; Mice, Inbred ICR; Molecular Structure; NF-E2-Related Factor 2; Plant Extracts; Plant Roots; Rats; Rats, Sprague-Dawley

2017
Antitussive and expectorant activities of licorice and its major compounds.
    Bioorganic & medicinal chemistry, 2018, 01-01, Volume: 26, Issue:1

    Topics: Administration, Oral; Ammonia; Animals; Antitussive Agents; Cough; Disease Models, Animal; Dose-Response Relationship, Drug; Expectorants; Glyburide; Glycyrrhiza; Male; Methysergide; Mice; Mice, Inbred ICR; Molecular Structure; Phenolsulfonphthalein; Plant Extracts; Structure-Activity Relationship

2018
Glabrene and isoliquiritigenin as tyrosinase inhibitors from licorice roots.
    Journal of agricultural and food chemistry, 2003, Feb-26, Volume: 51, Issue:5

    Topics: Cells, Cultured; Chalcone; Chalcones; Dose-Response Relationship, Drug; Glycyrrhiza; Humans; Isoflavones; Kinetics; Melanins; Melanocytes; Monophenol Monooxygenase; Peptides; Phenols; Plant Extracts; Plant Roots; Structure-Activity Relationship; Tyrosine

2003
Dual inhibitory effect of Glycyrrhiza glabra (GutGardā„¢) on COX and LOX products.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2011, Feb-15, Volume: 18, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Calcimycin; Cell Line; Chalcones; Dinoprostone; Glycyrrhiza; Glycyrrhizic Acid; HL-60 Cells; Humans; Isoflavones; Leukotriene B4; Lipopolysaccharides; Lipoxygenase; Mice; Phenols; Plant Extracts; Plant Roots; Prostaglandin-Endoperoxide Synthases; Thromboxane B2

2011
Modulation of lipopolysaccharide-induced pro-inflammatory mediators by an extract of Glycyrrhiza glabra and its phytoconstituents.
    Inflammopharmacology, 2011, Volume: 19, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Chalcones; Cytokines; Down-Regulation; Drug Discovery; Glycyrrhiza; Glycyrrhizic Acid; Inflammation Mediators; Interleukin-1beta; Interleukin-6; Isoflavones; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide; Phenols; Phytotherapy; Plant Extracts; Plant Roots

2011
Ultrasound-assisted deep eutectic solvents extraction of glabridin and isoliquiritigenin from Glycyrrhiza glabra: Optimization, extraction mechanism and in vitro bioactivities.
    Ultrasonics sonochemistry, 2022, Volume: 83

    Topics: Chalcones; Deep Eutectic Solvents; Glycyrrhiza; Isoflavones; Phenols; Plant Extracts; Solvents

2022