Compounds > glabridin
Page last updated: 2024-09-03

glabridin and genistein

glabridin has been researched along with genistein in 6 studies

Compound Research Comparison

Studies
(glabridin)		Trials
(glabridin)		Recent Studies (post-2010)
(glabridin)		Studies
(genistein)		Trials
(genistein)		Recent Studies (post-2010) (genistein)
17241227,4232042,311

Protein Interaction Comparison

ProteinTaxonomyglabridin (IC50)genistein (IC50)
Chain A, Estrogen receptor 1 (alpha)Homo sapiens (human)0.009
Maltase-glucoamylase, intestinalHomo sapiens (human)2.61
Steroid hormone receptor ERR2Homo sapiens (human)0.395
Tyrosine-protein kinase ABL1Homo sapiens (human)5.5
Epidermal growth factor receptorHomo sapiens (human)1.2
TransthyretinHomo sapiens (human)7.8
Estrogen receptorHomo sapiens (human)1.3477
Steroid hormone receptor ERR1Homo sapiens (human)0.01
Polyunsaturated fatty acid lipoxygenase ALOX15Oryctolagus cuniculus (rabbit)9.033
17-beta-hydroxysteroid dehydrogenase type 1Homo sapiens (human)2.21
Protein kinase C alpha typeHomo sapiens (human)1
cAMP-dependent protein kinase catalytic subunit alphaHomo sapiens (human)1
Amine oxidase [flavin-containing] AHomo sapiens (human)4.184
Thromboxane-A synthase Homo sapiens (human)7.72
Amine oxidase [flavin-containing] BHomo sapiens (human)3.9333
Dipeptidyl peptidase 4Homo sapiens (human)0.48
Proteasome subunit beta type-5Homo sapiens (human)9.26
Sodium-dependent serotonin transporterRattus norvegicus (Norway rat)0.395
Tyrosine-protein kinase CSKHomo sapiens (human)1
Dual specificity mitogen-activated protein kinase kinase 4Homo sapiens (human)0.4
Xanthine dehydrogenase/oxidaseBos taurus (cattle)1.73
Aldehyde oxidaseHomo sapiens (human)0.34
Integrase Human immunodeficiency virus 11.1
Estrogen receptor betaHomo sapiens (human)0.3706
Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein)Plasmodium falciparum (malaria parasite P. falciparum)7
Solute carrier organic anion transporter family member 1B3Homo sapiens (human)3.8905
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)7.85
Solute carrier organic anion transporter family member 1B1Homo sapiens (human)9.1201

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's5 (83.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Atrahimovich, D; Khatib, S; Vaya, J1
Kosaka, Y; Mizuguchi, M; Yokoyama, T1
Kuang, Y; Li, K; Lin, Y; Qiao, X; Sabir, G; Song, W; Wang, S; Ye, M1
Chen, K; Ji, S; Kuang, Y; Li, K; Lin, Y; Qiao, X; Song, W; Wang, S; Ye, M1
Jin, YS1
Khatib, S; Ofir, R; Tamir, S; Vaya, J1

Reviews

1 review(s) available for glabridin and genistein

ArticleYear
Recent advances in natural antifungal flavonoids and their derivatives.
    Bioorganic & medicinal chemistry letters, 2019, 10-01, Volume: 29, Issue:19

    Topics: Antifungal Agents; Biological Products; Flavonoids; Fungi; Humans; Mycoses

2019

Other Studies

5 other study(ies) available for glabridin and genistein

ArticleYear
The effects and mechanism of flavonoid-rePON1 interactions. Structure-activity relationship study.
    Bioorganic & medicinal chemistry, 2013, Jun-01, Volume: 21, Issue:11

    Topics: Allosteric Site; Aryldialkylphosphatase; Copper; Flavonoids; Humans; Lipoproteins, HDL; Lipoproteins, LDL; Molecular Docking Simulation; Oxidation-Reduction; Protein Binding; Protein Conformation; Recombinant Proteins; Spectrometry, Fluorescence; Structure-Activity Relationship; Tryptophan

2013
Crystal structures of human transthyretin complexed with glabridin.
    Journal of medicinal chemistry, 2014, Feb-13, Volume: 57, Issue:3

    Topics: Amyloid; Binding Sites; Crystallography, X-Ray; Humans; Isoflavones; Models, Molecular; Phenols; Prealbumin; Protein Binding; Protein Conformation; Protein Multimerization

2014
Screening for bioactive natural products from a 67-compound library of Glycyrrhiza inflata.
    Bioorganic & medicinal chemistry, 2017, 07-15, Volume: 25, Issue:14

    Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Biological Products; Cell Line, Tumor; Drug Screening Assays, Antitumor; Glycyrrhiza; HEK293 Cells; Hep G2 Cells; Humans; Lipopolysaccharides; Macrophages; MCF-7 Cells; Mice; Monophenol Monooxygenase; NF-kappa B; Plant Roots; Protein Tyrosine Phosphatase, Non-Receptor Type 1; RAW 264.7 Cells; Small Molecule Libraries

2017
Nrf2 activators from Glycyrrhiza inflata and their hepatoprotective activities against CCl
    Bioorganic & medicinal chemistry, 2017, 10-15, Volume: 25, Issue:20

    Topics: Administration, Oral; Animals; Carbon Tetrachloride; Cell Survival; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Dose-Response Relationship, Drug; Glycyrrhiza; Hep G2 Cells; Humans; Male; Mice; Mice, Inbred ICR; Molecular Structure; NF-E2-Related Factor 2; Plant Extracts; Plant Roots; Rats; Rats, Sprague-Dawley

2017
Inhibition of serotonin re-uptake by licorice constituents.
    Journal of molecular neuroscience : MN, 2003, Volume: 20, Issue:2

    Topics: Carrier Proteins; Cells, Cultured; Depressive Disorder; Dose-Response Relationship, Drug; Estradiol; Estrogens, Non-Steroidal; Female; Flavonoids; Genistein; Glycyrrhiza; Humans; Isoflavones; Membrane Glycoproteins; Membrane Transport Proteins; Menopause; Molecular Structure; Nerve Tissue Proteins; Phenols; Phytoestrogens; Plant Extracts; Plant Preparations; Resorcinols; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins

2003