gl 331 has been researched along with podophyllotoxin in 4 studies
| Studies (gl 331) | Trials (gl 331) | Recent Studies (post-2010) (gl 331) | Studies (podophyllotoxin) | Trials (podophyllotoxin) | Recent Studies (post-2010) (podophyllotoxin) |
|---|---|---|---|---|---|
| 28 | 1 | 4 | 3,119 | 226 | 782 |
| Protein | Taxonomy | gl 331 (IC50) | podophyllotoxin (IC50) |
|---|---|---|---|
| nuclear receptor subfamily 0 group B member 1 | Homo sapiens (human) | 2.145 | |
| Tubulin alpha-1A chain | Sus scrofa (pig) | 0.6733 | |
| Tubulin beta chain | Sus scrofa (pig) | 0.622 | |
| Glucocorticoid receptor | Homo sapiens (human) | 0.014 | |
| Tubulin beta-4A chain | Homo sapiens (human) | 1.7233 | |
| Tubulin beta chain | Homo sapiens (human) | 1.7233 | |
| Cytochrome P450 3A4 | Homo sapiens (human) | 0.6 | |
| Tubulin alpha-3C chain | Homo sapiens (human) | 1.7233 | |
| Cytochrome P450 2C9 | Homo sapiens (human) | 4 | |
| Cytochrome P450 2C19 | Homo sapiens (human) | 5 | |
| Tubulin alpha-1B chain | Homo sapiens (human) | 1.7233 | |
| Tubulin alpha-4A chain | Homo sapiens (human) | 1.7233 | |
| Tubulin beta-4B chain | Homo sapiens (human) | 1.7233 | |
| Tubulin beta-3 chain | Homo sapiens (human) | 1.7233 | |
| Tubulin beta-2A chain | Homo sapiens (human) | 1.7233 | |
| Tubulin beta-8 chain | Homo sapiens (human) | 1.7233 | |
| Calcium-activated potassium channel subunit alpha-1 | Rattus norvegicus (Norway rat) | 0.56 | |
| Tubulin beta-2B chain | Bos taurus (cattle) | 0.8685 | |
| Tubulin alpha-3E chain | Homo sapiens (human) | 1.7233 | |
| Tubulin alpha-1A chain | Homo sapiens (human) | 1.7233 | |
| Similar to alpha-tubulin isoform 1 | Bos taurus (cattle) | 0.907 | |
| Similar to alpha-tubulin isoform 1 | Bos taurus (cattle) | 0.7744 | |
| Tubulin alpha-1C chain | Homo sapiens (human) | 1.7233 | |
| Tubulin beta-6 chain | Homo sapiens (human) | 1.7233 | |
| Tubulin beta-2B chain | Homo sapiens (human) | 1.7233 | |
| Tubulin beta-1 chain | Homo sapiens (human) | 1.7233 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bastow, KF; Huang, ES; Lee, KH; Tachibana, Y; VanVliet, DS | 1 |
| Lee, KH | 1 |
| Diao, Q; Gao, F; Gao, M; Sun, Z; Wang, P; Xiao, J | 1 |
| Chao, Y; Chen, LL; Chen, LT; Chen, MH; Huang, TS; Lee, CC; Shu, CH; Whang-Peng, J; Yuan, CC | 1 |
2 review(s) available for gl 331 and podophyllotoxin
| Article | Year |
|---|---|
Discovery and development of natural product-derived chemotherapeutic agents based on a medicinal chemistry approach.
Topics: Anti-HIV Agents; Biological Factors; Drug Design; Molecular Structure; Pharmaceutical Preparations; Plants, Medicinal | 2010 |
Recent advances of podophyllotoxin/epipodophyllotoxin hybrids in anticancer activity, mode of action, and structure-activity relationship: An update (2010-2020).
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Resistance, Neoplasm; Humans; Molecular Structure; Podophyllotoxin; Stereoisomerism; Structure-Activity Relationship | 2020 |
2 other study(ies) available for gl 331 and podophyllotoxin
| Article | Year |
|---|---|
Antitumor agents. 207. Design, synthesis, and biological testing of 4beta-anilino-2-fluoro-4'-demethylpodophyllotoxin analogues as cytotoxic and antiviral agents.
Topics: Animals; Antineoplastic Agents; Antiviral Agents; Chlorocebus aethiops; DNA; Drug Design; Drug Screening Assays, Antitumor; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Microbial Sensitivity Tests; Nucleic Acid Hybridization; Podophyllotoxin; Structure-Activity Relationship; Tumor Cells, Cultured; Vero Cells | 2001 |
A novel podophyllotoxin-derived compound GL331 is more potent than its congener VP-16 in killing refractory cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Death; Drug Resistance, Multiple; Drug Screening Assays, Antitumor; Etoposide; Humans; Neoplasms; Podophyllotoxin; Tumor Cells, Cultured | 1999 |