Page last updated: 2024-08-26

gitoxin and digoxin

gitoxin has been researched along with digoxin in 43 studies

Research

Studies (43)

Timeframe	Studies, this research(%)	All Research%
pre-1990	28 (65.12)	18.7374
1990's	8 (18.60)	18.2507
2000's	6 (13.95)	29.6817
2010's	1 (2.33)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Baures, PW; Eggleston, DS; Faucette, L; Hemling, ME; Johnson, RK; Patil, AD; Westley, JW	1
Ball, WJ; Farr, CD; Fishwild, DM; Nair, AC; Tabet, MR; Wang, X; Welsh, WJ	1
Austin, CA; Ayuso, MJ; Azrak, SS; Cortés, F; López-Lázaro, M; Pastor, N	1
Lesne, M; Pellegrin, P; Verbeke, N; Vienne, A	1
Lesne, M	1
Glusa, E; Haustein, KO	2
Bruccoleri, RE; Haber, E; Herzenberg, LA; Jager, GC; Margolies, MN; Mudgett-Hunter, M; Novotny, J; Panka, DJ; Parks, DR; Schildbach, JF	1
Coates, ML; Wilkins, CL	1
Lesne, M; Pellegrin, P	3
Haustein, KO	1
Kadima, LN; Lesne, M; Lhoest, G	1
Kadima, LN; Lesne, M	2
Dolphen, R; Lesne, M	1
Brasseur, L; Col, J; Lesne, M; Wijns, W	1
Chang, CY; Jeffrey, PD; Kussie, PH; Margolies, MN; Schildbach, JF; Sheriff, S	1
Bauer, R; Haustein, KO	1
Ponder, GW; Stewart, JT	2
Dessi, JL; Self, CH; Winger, LA	1
Asakawa, Y; Asano, M; Fujita, M; Hashimoto, T; Hidaka, H; Hotta, Y; Nagai, S; Nagatsu, A; Nakamura, Y; Sakakibara, J; Shibatomi, K; Takemoto, K; Takeya, K; Ueda, T	1
Jeffrey, PD; Krykbaev, RA; Margolies, MN; Short, MK	1
HACKENBERG, U	1
FRUYTIER, JF; VAN PINXTEREN, JA	1
DUGHERA, L; NAZZI, V	1
SCHLEGEL, H	1
ISHII, H; OKUMURA, T; OYAMA, Y; SATOH, D; WADA, T	1
ISHII, H; OYAMA, Y; SATOH, D	1
LUKESCH, H	1
GROLLEAU, R; HERTAULT, J; LATOUR, H; PUECH, P	1
CALANDRE, L; RIVES, J	1
HEUCHEL, G; RASCHICK, C	1
Ayuso, MJ; Cortés, F; López-Lázaro, M; Martín-Cordero, C; Navarro, E; Palma De La Peña, N; Pastor, N; Toro, MV	1
HILTON, JG	1
FRANCK, B; ZOLLNER, G	1
HOTOVY, R	1
JENSEN, KB	1
Joksić, G; Krinulović, K; Krstić, D; Momić, T; Spasojević-Tisma, V; Vasić, V	1
Dhathathreyan, A; Muthuselvi, L	1
Hong, SP; Kwon, HJ; Lee, SI; Lee, YM; Park, YD; Sim, HJ	1

Trials

1 trial(s) available for gitoxin and digoxin

Article	Year
Extraordinary efficacy of 16 alpha-gitoxin, an ultra-short acting semi-synthetic digitalis glycoside. International journal of clinical pharmacology and therapeutics, 1994, Volume: 32, Issue:6 Topics: Administration, Oral; Adult; Cardiac Glycosides; Cardiotonic Agents; Digoxin; Electrocardiography; Female; Heart Rate; Humans; Injections, Intravenous; Male; Radioimmunoassay	1994

Other Studies

42 other study(ies) available for gitoxin and digoxin

Article	Year
A screen for inhibitors of DNA recombination: identification of two new spirostanol glycosides from Chamaedorea linearis. Journal of natural products, 1993, Volume: 56, Issue:9 Topics: Animals; Antineoplastic Agents, Phytogenic; Crystallography, X-Ray; DNA; DNA Damage; DNA Repair; Drug Screening Assays, Antitumor; Ecuador; Glycosides; Leukemia L1210; Magnetic Resonance Spectroscopy; Mice; Plants, Medicinal; Recombination, Genetic; Saccharomyces cerevisiae; Spirostans	1993
Three-dimensional quantitative structure-activity relationship analysis of ligand binding to human sequence antidigoxin monoclonal antibodies using comparative molecular field analysis. Journal of medicinal chemistry, 2002, Jul-18, Volume: 45, Issue:15 Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Antibody Specificity; Binding Sites, Antibody; Binding, Competitive; Carbohydrate Sequence; Digoxin; Enzyme-Linked Immunosorbent Assay; Humans; Immunoglobulin Fab Fragments; Mice; Mice, Transgenic; Models, Molecular; Molecular Sequence Data; Ouabain; Progesterone; Quantitative Structure-Activity Relationship; Radioligand Assay	2002
Digitoxin inhibits the growth of cancer cell lines at concentrations commonly found in cardiac patients. Journal of natural products, 2005, Volume: 68, Issue:11 Topics: Antineoplastic Agents; Cardiotonic Agents; Digitoxin; DNA Damage; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Humans; Inhibitory Concentration 50; Molecular Structure; Tumor Cells, Cultured	2005
The binding of gitoxin to human plasma proteins. European journal of clinical pharmacology, 1979, Volume: 16, Issue:5 Topics: Blood Proteins; Dialysis; Digitoxin; Digoxin; Humans; Isoelectric Focusing; Isomerism; Protein Binding; Ultracentrifugation	1979
Pharmacological reevaluation of gitoxin in man. International journal of clinical pharmacology and biopharmacy, 1978, Volume: 16, Issue:10 Topics: Administration, Oral; Adult; Digitalis Glycosides; Digoxin; Female; Half-Life; Humans; Injections, Intravenous; Kidney; Male; Middle Aged	1978
Kinetic properties of 3H-16alpha-gitoxin in the isolated guinea-pig atrium. Acta biologica et medica Germanica, 1978, Volume: 37, Issue:4 Topics: Animals; Digitoxin; Digoxin; Female; Guinea Pigs; Heart Atria; Isomerism; Kinetics; Male; Myocardial Contraction; Myocardium; Ouabain	1978
Altered hapten recognition by two anti-digoxin hybridoma variants due to variable region point mutations. The Journal of biological chemistry, 1991, Mar-05, Volume: 266, Issue:7 Topics: Amino Acid Sequence; Antibodies, Monoclonal; Antibody Specificity; Base Sequence; Digoxigenin; Digoxin; Genes, Immunoglobulin; Haptens; Hybridomas; Immunoglobulin Idiotypes; Models, Molecular; Molecular Sequence Data; Mutation; Ouabain; Structure-Activity Relationship	1991
Laser desorption/Fourier transform mass spectra of glycoalkaloids and steroid glycosides. Biomedical & environmental mass spectrometry, 1986, Volume: 13, Issue:4 Topics: Alkaloids; Digitonin; Digoxin; Fourier Analysis; Glycosides; Lanatosides; Lasers; Mass Spectrometry; Solanine; Steroids; Tomatine	1986
Gitoxin--a challenger for digoxin? Drug intelligence & clinical pharmacy, 1985, Volume: 19, Issue:12 Topics: Digoxin; Heart Diseases; Humans; Intestinal Absorption	1985
Therapeutic range of cardiac glycosides. Basic research in cardiology, 1984, Volume: 79 Suppl Topics: Animals; Cardiac Glycosides; Cats; Digoxin; Dogs; Guinea Pigs; Humans; Isomerism; Myocardial Contraction; Ouabain; Purkinje Fibers; Sodium-Potassium-Exchanging ATPase; Stimulation, Chemical; Structure-Activity Relationship; Systole	1984
Hepatic clearance of gitoxin: pharmacokinetic study on rabbit isolated liver. Influence of protein binding and comparison with digoxin. European journal of drug metabolism and pharmacokinetics, 1983, Volume: 8, Issue:1 Topics: Animals; Bile; Digoxin; In Vitro Techniques; Kinetics; Liver; Male; Perfusion; Protein Binding; Rabbits; Time Factors	1983
Isolation and mass spectrometric identification of gitoxin metabolites excreted in bile. European journal of drug metabolism and pharmacokinetics, 1982, Volume: 7, Issue:2 Topics: Bile; Digoxin; Humans; Mass Spectrometry	1982
Studies on the pharmacokinetics and the metabolism of gitoxin in the guinea-pig: II. the enteral absorption and the enterohepatic recirculation. Archives internationales de pharmacodynamie et de therapie, 1982, Volume: 258, Issue:1 Topics: Animals; Bile; Digoxin; Female; Guinea Pigs; Intestinal Absorption; Intubation, Gastrointestinal; Kinetics; Liver; Male; Tissue Distribution	1982
Metabolism of gitoxin by the rabbit isolated liver. Archives internationales de pharmacodynamie et de therapie, 1982, Volume: 260, Issue:2 Topics: Animals; Biotransformation; Digoxin; In Vitro Techniques; Liver; Rabbits; Time Factors	1982
Uptake and pharmacological effect of gitoxin and gitaloxin in rat and guinea-pig perfused hearts. Comparison with digitoxin and digoxin. Arzneimittel-Forschung, 1980, Volume: 30, Issue:4 Topics: Animals; Digitoxin; Digoxin; Extracellular Space; Female; Guinea Pigs; Heart; In Vitro Techniques; Male; Myocardial Contraction; Myocardium; Rats; Species Specificity	1980
Studies on cardioactive steroids. V. Structure-activity relationships of derivatives of 16 alpha-gitoxin. Pharmacology, 1980, Volume: 21, Issue:6 Topics: Acetyldigoxins; Animals; Arrhythmias, Cardiac; Cardiac Glycosides; Digoxin; Dogs; Dose-Response Relationship, Drug; Female; Guinea Pigs; Heart; Heart Rate; Isomerism; Male; Myocardial Contraction; Stimulation, Chemical; Structure-Activity Relationship	1980
Contrasting effect on cardiac output of digoxin and gitoxin in humans during congestive heart failure. International journal of clinical pharmacology, therapy, and toxicology, 1981, Volume: 19, Issue:7 Topics: Aged; Cardiac Glycosides; Cardiac Output; Digoxin; Female; Heart Failure; Hemodynamics; Humans; Male; Time Factors	1981
Studies on the pharmacokinetics and the metabolism of gitoxin in the guinea-pig: I. Disposition kinetics following an i.v. bolus of 3H-gitoxin. Archives internationales de pharmacodynamie et de therapie, 1980, Volume: 245, Issue:1 Topics: Animals; Bile; Biotransformation; Digestive System; Digitalis Glycosides; Digoxin; Female; Guinea Pigs; Injections, Intravenous; Kinetics; Male; Solubility; Time Factors	1980
Structure and specificity of the anti-digoxin antibody 40-50. Journal of molecular biology, 1995, Apr-28, Volume: 248, Issue:2 Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Antibody Affinity; Antibody Specificity; Base Sequence; Binding Sites; Cloning, Molecular; Crystallography, X-Ray; Digoxin; Haptens; Hybridomas; Immunoglobulin Fab Fragments; Mice; Models, Molecular; Molecular Sequence Data; Ouabain; Protein Conformation; Sequence Analysis, DNA	1995
Recovery of digoxin and related glycosides from an injection dosage form by liquid-liquid and solid-phase extraction. Journal of pharmaceutical and biomedical analysis, 1994, Volume: 12, Issue:5 Topics: Chromatography, High Pressure Liquid; Digoxigenin; Digoxin; Dosage Forms; Glycosides; Reference Standards	1994
High-performance thin-layer chromatographic determination of digoxin and related compounds, digoxigenin bisdigitoxoside and gitoxin, in digoxin drug substance and tablets. Journal of chromatography. A, 1994, Jan-21, Volume: 659, Issue:1 Topics: Carbohydrate Sequence; Chromatography, Thin Layer; Digoxigenin; Digoxin; Molecular Sequence Data; Spectrophotometry; Tablets	1994
Ultra-specific immunoassays for small molecules: roles of wash steps and multiple binding formats. Clinical chemistry, 1996, Volume: 42, Issue:9 Topics: Antibodies, Monoclonal; Digitoxigenin; Digitoxin; Digoxigenin; Digoxin; Immunoassay; Sensitivity and Specificity; Strophanthidin	1996
Studies on cardiac ingredients of plants. XIII: Chemical modification of gitoxin to cardiotonic compounds without vascular effect. Chemical & pharmaceutical bulletin, 1997, Volume: 45, Issue:4 Topics: Animals; Bufanolides; Cardiotonic Agents; Digoxin; Dogs; Guinea Pigs; Kidney; Muscle Contraction; Muscle, Smooth, Vascular; Plants, Medicinal; Rats; Sodium-Potassium-Exchanging ATPase; Stimulation, Chemical; Structure-Activity Relationship	1997
Complementary combining site contact residue mutations of the anti-digoxin Fab 26-10 permit high affinity wild-type binding. The Journal of biological chemistry, 2002, May-10, Volume: 277, Issue:19 Topics: Acetyldigoxins; Animals; Antibodies, Monoclonal; Arginine; Binding Sites; Crystallography, X-Ray; Digoxin; Enzyme-Linked Immunosorbent Assay; Genetic Vectors; Haptens; Kinetics; Mice; Models, Chemical; Mutagenesis, Site-Directed; Mutation; Protein Binding; Serum Albumin; Valine	2002
[Enteral resorption of lanatosid A, B and C and gitoxin in cat and dog]. Arzneimittel-Forschung, 1953, Volume: 3, Issue:11 Topics: Animals; Cats; Digitalis; Digoxin; Dogs; Duodenum; Plant Extracts	1953
[The fluorometric determination of gitoxin]. Pharmaceutisch weekblad, 1954, Feb-13, Volume: 89, Issue:7-8 Topics: Digitalis; Digitalis Glycosides; Digoxin; Fluorometry; Plant Extracts	1954
[Clinical use of digitalis; combined digitoxin and gitoxin (crystafolin CIBA) in the therapy of cardiovascular disorders]. Archivio per le scienze mediche, 1954, Volume: 98, Issue:5 Topics: Cardiovascular Diseases; Digitalis; Digitalis Glycosides; Digitoxin; Digoxin; Heart Failure	1954
[Clinical studies on gitoxin. I. The problem of the effects of enteral gitoxin administration on the human heart]. Zeitschrift fur Kreislaufforschung, 1955, Volume: 44, Issue:15-16 Topics: Digitalis; Digitalis Glycosides; Digoxin; Heart; Heart Diseases	1955
Studies on digitalis glycosides. VII. Gitoroside, digitalonin, and gitoxin pentaacetate. Pharmaceutical bulletin, 1957, Volume: 5, Issue:3 Topics: Digitalis; Digitalis Glycosides; Digoxin; Humans; Plant Extracts	1957
Studies on digitalis glycosides: acetylgitoxin-alpha from gitoxin. Pharmaceutical bulletin, 1957, Volume: 5, Issue:5 Topics: Acetyldigitoxins; Digitalis; Digitalis Glycosides; Digoxin; Humans; Plant Extracts	1957
[Preparation of pure digitoxin & gitoxin]. Die Pharmazie, 1958, Volume: 13, Issue:6 Topics: Digitalis; Digitalis Glycosides; Digitoxin; Digoxin; Plant Extracts	1958
[CLINICAL STUDY OF A NEW DIGITALIS DRUG: 16-FORMYL-GITOXIN]. Montpellier medical, 1964, Volume: 65 Topics: Adolescent; Biomedical Research; Chemistry, Pharmaceutical; Digitalis; Digitalis Glycosides; Digoxin; Geriatrics; Heart Diseases; Pharmacology; Pharmacy; Toxicology	1964
[CLINICAL TRIAL OF A NEW CARDIOTONIC AGENT (16-FORMYL-GITOXIN) IN PATIENTS WITH CARDIAC INSUFFICIENCY]. Revista espanola de cardiologia, 1964, Volume: 17 Topics: Biomedical Research; Cardiotonic Agents; Digitalis Glycosides; Digoxin; Diuretics; Drug Therapy; Electrocardiography; Heart Failure; Toxicology	1964
[CARDIAC THERAPY WITH PENTA-ACETYL-GITOXIN, A NEW HALF-SYNTHETIC PURPUREAGLYCOSIDE]. Zeitschrift fur arztliche Fortbildung, 1964, Aug-01, Volume: 58 Topics: Arrhythmias, Cardiac; Cardiac Glycosides; Digoxin; Diuretics; Drug Therapy; Heart Failure; Humans; Rubiaceae	1964
Anti-tumour activity of Digitalis purpurea L. subsp. heywoodii. Planta medica, 2003, Volume: 69, Issue:8 Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Cardenolides; Cell Line, Tumor; Digitalis; Digoxin; Etoposide; Humans; Inhibitory Concentration 50; Kidney Neoplasms; Phytotherapy; Plant Extracts; Plant Leaves	2003
A polarographic method for the determination of digitoxin and gitoxin and its application to pharmacological studies. The Journal of pharmacology and experimental therapeutics, 1950, Volume: 100, Issue:3 Topics: Blood; Digitalis; Digitalis Glycosides; Digitoxin; Digoxin; Humans; Plant Extracts	1950
[Biologic evaluation of the effects of gitoxin with the aid of a surface active solvent]. Die Pharmazie, 1950, Volume: 5, Issue:12 Topics: Biological Products; Digoxin; Gliotoxin; Solvents	1950
[Enteral resorption of digitoxin and gitoxin]. Arzneimittel-Forschung, 1951, Volume: 1, Issue:4 Topics: Cardiac Glycosides; Digitalis; Digitalis Glycosides; Digitoxin; Digoxin; Glycosides; Heart; Humans; Intestines	1951
Paper-chromatographic separation and fluorimetric determination of gitoxigenin, gitoxin, and purpureaglycoside B. Acta pharmacologica et toxicologica, 1952, Volume: 8, Issue:2 Topics: Cardenolides; Chromatography, Paper; Digitalis; Digitalis Glycosides; Digoxin	1952
Effects of digoxin and gitoxin on the enzymatic activity and kinetic parameters of Na+/K+-ATPase. Journal of enzyme inhibition and medicinal chemistry, 2004, Volume: 19, Issue:5 Topics: Animals; Cerebral Cortex; Digoxin; Dose-Response Relationship, Drug; Enzyme Activation; Erythrocyte Membrane; Humans; Kinetics; Molecular Conformation; Sodium-Potassium-Exchanging ATPase; Structure-Activity Relationship; Swine	2004
Simple coacervates of zein to encapsulate Gitoxin. Colloids and surfaces. B, Biointerfaces, 2006, Aug-01, Volume: 51, Issue:1 Topics: Cardiotonic Agents; Cell Adhesion; Delayed-Action Preparations; Digoxin; Drug Delivery Systems; In Vitro Techniques; Kinetics; Lasers; Light; Materials Testing; Microspheres; Particle Size; Scattering, Radiation; Viscosity; Zein	2006
HPLC method validation for Digitalis and its analogue by pulsed amperometric detection. Journal of pharmaceutical and biomedical analysis, 2011, Jan-05, Volume: 54, Issue:1 Topics: Acetonitriles; Cardiac Glycosides; Chemistry Techniques, Analytical; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Digitalis; Digitonin; Digitoxin; Digoxin; Electrochemistry; Models, Chemical; Plant Leaves; Reproducibility of Results; Solvents; Temperature	2011