ginsenoside rh2 has been researched along with protopanaxadiol in 17 studies
| Studies (ginsenoside rh2) | Trials (ginsenoside rh2) | Recent Studies (post-2010) (ginsenoside rh2) | Studies (protopanaxadiol) | Trials (protopanaxadiol) | Recent Studies (post-2010) (protopanaxadiol) |
|---|---|---|---|---|---|
| 295 | 1 | 200 | 226 | 3 | 174 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.88) | 18.2507 |
| 2000's | 8 (47.06) | 29.6817 |
| 2010's | 5 (29.41) | 24.3611 |
| 2020's | 3 (17.65) | 2.80 |
| Authors | Studies |
|---|---|
| Maeda, M; Odashima, S; Ota, T | 1 |
| Kitts, DD; Popovich, DG | 2 |
| Chen, M; Huang, CR; Jiang, XL; Li, H; Lv, H; Roberts, M; Wang, GJ; Wang, R; Xie, HT | 1 |
| Chen, X; Li, K; Li, X; Xu, J; Zhong, D | 1 |
| Jiang, XL; Li, H; Sun, JG; Tucker, I; Wang, GJ; Wang, R; Wang, W; Xie, HT; Xie, YY; Xu, MJ; Zhao, XC | 1 |
| Duan, Y; Law, V; Nicholson, R; Zheng, J | 1 |
| Hill, DL; Rayburn, ER; Wang, H; Wang, W; Zhang, R; Zhao, Y | 1 |
| Duan, Y; Nicholson, RA | 1 |
| Li, Z; Lou, C; Yang, H; Zhang, H; Zhong, Z; Zhou, Z | 1 |
| Chen, Y; Gao, Y; Jin, Y; Li, X; Li, Y; Sun, T; Yang, J | 1 |
| Chen, X; Ding, Y; Le, J; Li, X; Peng, M; Yang, Y; Yi, Y; Zhang, T | 1 |
| Bai, G; Guo, Y; Hou, Y; Jiang, M; Jiang, Z; Jiao, Y; Kim, U; Li, C; Ma, X; Wang, Z | 1 |
| Chen, G; Du, Y; Fan, H; Meng, Q; Wang, N; Xu, H; Yang, Q; Yang, X; Zhang, J | 1 |
| He, B; Li, Y; Ma, W; Ma, Y; Qin, S; Zhao, L | 1 |
| Dai, L; Hu, Y; Min, J; Qin, L; Xue, J; Zhang, J | 1 |
| Dai, L; Guo, RT; Hu, Y; Hu, Z; Huang, JW; Min, J; Qin, L; Sun, Y | 1 |
17 other study(ies) available for ginsenoside rh2 and protopanaxadiol
| Article | Year |
|---|---|
Mechanism of action of ginsenoside Rh2: uptake and metabolism of ginsenoside Rh2 by cultured B16 melanoma cells.
Topics: Animals; Cell Cycle; Ginsenosides; Glycosylation; Melanoma, Experimental; Mice; Molecular Structure; Panax; Plants, Medicinal; Sapogenins; Saponins; Serum Albumin, Bovine; Triterpenes; Tumor Cells, Cultured | 1991 |
Ginsenosides 20(S)-protopanaxadiol and Rh2 reduce cell proliferation and increase sub-G1 cells in two cultured intestinal cell lines, Int-407 and Caco-2.
Topics: Apoptosis; Caco-2 Cells; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; G1 Phase; Ginsenosides; Humans; L-Lactate Dehydrogenase; Plant Roots; Sapogenins; Structure-Activity Relationship; Time Factors; Triterpenes; United States | 2004 |
Mechanistic studies on protopanaxadiol, Rh2, and ginseng (Panax quinquefolius) extract induced cytotoxicity in intestinal Caco-2 cells.
Topics: Annexin A5; Apoptosis; Caco-2 Cells; Caspases; Cell Fractionation; Cell Survival; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Ginsenosides; Humans; Isomerism; L-Lactate Dehydrogenase; Mass Spectrometry; Molecular Structure; Panax; Plant Extracts; Propidium; Sapogenins; Spectrometry, Mass, Electrospray Ionization; Time Factors; Triterpenes | 2004 |
Uptake and metabolism of ginsenoside Rh2 and its aglycon protopanaxadiol by Caco-2 cells.
Topics: Caco-2 Cells; Ginsenosides; Humans; Sapogenins; Triterpenes | 2005 |
Liquid chromatography/tandem mass spectrometry for pharmacokinetic studies of 20(R)-ginsenoside Rg3 in dog.
Topics: Administration, Oral; Animals; Blood Chemical Analysis; Chromatography, Liquid; Dogs; Female; Ginsenosides; Injections, Intra-Arterial; Male; Mass Spectrometry; Metabolic Clearance Rate; Reproducibility of Results; Sapogenins; Sensitivity and Specificity; Triterpenes | 2005 |
High performance liquid chromatographic-mass spectrometric determination of ginsenoside Rg3 and its metabolites in rat plasma using solid-phase extraction for pharmacokinetic studies.
Topics: Animals; Chromatography, High Pressure Liquid; Drug Stability; Freezing; Ginsenosides; Rats; Rats, Sprague-Dawley; Sapogenins; Spectrometry, Mass, Electrospray Ionization; Triterpenes | 2005 |
Natural products from ginseng inhibit [3H]batrachotoxinin A 20-alpha-benzoate binding to Na+ channels in mammalian brain.
Topics: Animals; Batrachotoxins; Binding, Competitive; Cell Membrane; Cerebral Cortex; Dose-Response Relationship, Drug; Ginsenosides; Kinetics; Male; Mice; Molecular Structure; Neurons; Panax; Plant Extracts; Radioligand Assay; Sapogenins; Sodium Channels; Solubility; Synaptosomes; Triterpenes; Tritium | 2006 |
20(S)-25-methoxyl-dammarane-3beta, 12beta, 20-triol, a novel natural product for prostate cancer therapy: activity in vitro and in vivo and mechanisms of action.
Topics: Animals; Apoptosis; Biomarkers, Tumor; Cell Cycle; Cell Proliferation; Drugs, Chinese Herbal; Gene Expression Regulation, Neoplastic; Ginsenosides; Humans; In Vitro Techniques; Male; Mice; Mice, Nude; Prostate-Specific Antigen; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sapogenins; Survival Rate; Triterpenes; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2008 |
20(S)-protopanaxadiol and the ginsenoside Rh2 inhibit Na+ channel-activated depolarization and Na+ channel-dependent amino acid neurotransmitter release in synaptic fractions isolated from mammalian brain.
Topics: Animals; Brain; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Ginsenosides; Glutamic Acid; In Vitro Techniques; Male; Membrane Potentials; Mice; Sapogenins; Sodium Channel Blockers; Sodium Channels; Synaptosomes; Tetrodotoxin; Triterpenes; Veratridine | 2008 |
Antidepressant-like effects of ginsenosides: A comparison of ginsenoside Rb3 and its four deglycosylated derivatives, Rg3, Rh2, compound K, and 20(S)-protopanaxadiol in mice models of despair.
Topics: Adrenocorticotropic Hormone; Animals; Antidepressive Agents; Brain Chemistry; Corticosterone; Depressive Disorder; Ginsenosides; Hindlimb Suspension; Male; Mice; Motor Activity; Neurotransmitter Agents; Sapogenins; Swimming | 2016 |
Semisynthesis and bioactive evaluation of oxidized products from 20(S)-ginsenoside Rg3, Rh2, protopanaxadiol (PPD) and their 20(R)-epimers as cytotoxic agents.
Topics: Antineoplastic Agents; Chemistry Techniques, Synthetic; Ginsenosides; HeLa Cells; Hep G2 Cells; Humans; Oxidation-Reduction; Sapogenins; Stereoisomerism; Structure-Activity Relationship; Triterpenes | 2016 |
Stereoselective pharmacokinetic and metabolism studies of 20(S)- and 20(R)-ginsenoside Rg₃ epimers in rat plasma by liquid chromatography-electrospray ionization mass spectrometry.
Topics: Animals; Chromatography, Liquid; Ginsenosides; Male; Plasma; Rats; Rats, Sprague-Dawley; Sapogenins; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism; Tandem Mass Spectrometry | 2016 |
Quantitative Proteomics Combined with Affinity MS Revealed the Molecular Mechanism of Ginsenoside Antitumor Effects.
Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Line, Tumor; Cell Survival; Ginsenosides; Guanosine Triphosphate; Humans; Lung Neoplasms; Molecular Docking Simulation; Neoplasm Proteins; Protein Binding; Protein Conformation; Proteomics; ras Proteins; Sapogenins | 2019 |
In vitro and in silico evaluation of stereoselective effect of ginsenoside isomers on platelet P2Y
Topics: Animals; Blood Platelets; Fibrinolytic Agents; Ginsenosides; Glycosides; Humans; Male; Molecular Docking Simulation; Panax; Plants, Medicinal; Platelet Activation; Platelet Aggregation; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Sapogenins; Stereoisomerism | 2019 |
Oriented efficient biosynthesis of rare ginsenoside Rh2 from PPD by compiling UGT-Yjic mutant with sucrose synthase.
Topics: Amino Acid Substitution; Bacillus subtilis; Biocatalysis; Ginsenosides; Glucosyltransferases; Glycosylation; Mutant Proteins; Mutation; Sapogenins | 2020 |
Biocatalytic synthesis of ginsenoside Rh2 using Arabidopsis thaliana glucosyltransferase-catalyzed coupled reactions.
Topics: Arabidopsis; Batch Cell Culture Techniques; Biocatalysis; Biosynthetic Pathways; Drugs, Chinese Herbal; Ginsenosides; Glucosyltransferases; Panax; Sapogenins; Saponins; Triterpenes; Uridine Diphosphate | 2020 |
Structural dissection of unnatural ginsenoside-biosynthetic UDP-glycosyltransferase Bs-YjiC from Bacillus subtilis for substrate promiscuity.
Topics: Bacillus subtilis; Bacterial Proteins; Binding Sites; Crystallography, X-Ray; Ginsenosides; Glycosylation; Glycosyltransferases; Models, Molecular; Molecular Docking Simulation; Protein Domains; Sapogenins; Substrate Specificity; Uridine Diphosphate; Uridine Diphosphate Glucose | 2021 |