ginsenoside rh2 has been researched along with beta-escin in 33 studies
| Studies (ginsenoside rh2) | Trials (ginsenoside rh2) | Recent Studies (post-2010) (ginsenoside rh2) | Studies (beta-escin) | Trials (beta-escin) | Recent Studies (post-2010) (beta-escin) |
|---|---|---|---|---|---|
| 295 | 1 | 200 | 14,137 | 211 | 6,278 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (9.09) | 18.7374 |
| 1990's | 19 (57.58) | 18.2507 |
| 2000's | 6 (18.18) | 29.6817 |
| 2010's | 2 (6.06) | 24.3611 |
| 2020's | 3 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Lu, H; Yuan, C; Zhao, Y | 1 |
| Maeda, M; Odashima, S; Ota, T | 1 |
| Hirata, J; Kikuchi, Y; Kita, T; Nagata, I; Sasa, H; Tode, T | 1 |
| Abe, H; Fujikawa-Yamamoto, K; Odashima, S; Ota, T | 1 |
| Chen, YJ; Pei, YP; Xie, H; Xu, SX; Yao, XS | 1 |
| Cheng, YJ; Ma, QF; Pei, YP; Su, SX; Xie, H; Yao, XS | 1 |
| Kohno, H; Maeda, M; Odashima, S; Ota, T; Tanino, M | 1 |
| Hirata, J; Imaizumi, E; Kikuchi, Y; Kita, T; Nagata, I; Tode, T | 2 |
| Chung, HT; Kang, HS; Kim, HD; Kim, KW; Lee, CH; Park, YC | 1 |
| Maeda, M; Ninomiya-Tsuji, J; Odashima, S; Ota, T; Tatsuka, M | 1 |
| Chung, E; Kim, SI; Lee, KY; Lee, SK; Lee, YH; Park, JA | 1 |
| Byun, BH; Joe, CO; Kim, SI; Shin, I; Yoon, YS | 1 |
| Kim, KW; Lee, KY; Lee, SK; Oh, YJ; Park, JA | 1 |
| Kashimoto, T; Kudo, K; Tachikawa, E; Takahashi, E | 1 |
| Kim, DS; Kim, SI; Kim, YS | 1 |
| Hirata, J; Ishii, K; Kikuchi, Y; Kita, T; Kudoh, K; Nagata, I; Nakata, H; Shinomiya, N; Tode, T | 1 |
| Kim, KW; Kim, SI; Lee, SK; Park, JA | 1 |
| Han, R; Xia, LJ | 1 |
| Choi, S; Choi, YH; Chung, H; Kim, DK; Kim, K; Kim, ND; Kim, SI; Oh, M | 1 |
| Kim, HE; Lee, SK; Oh, JH; Oh, YJ | 1 |
| Jin, SH; Kim, SI; Kim, YS; Lee, YH; Park, JD | 2 |
| Jin, YH; Lee, SK; Lee, YH; Yoo, KJ | 1 |
| Maeda, M; Ota, T; Tatsuka, M | 1 |
| Bae, EA; Han, MJ; Kim, DH; Kim, EJ | 1 |
| Han, SJ; Kim, DH; Kim, SW; Lee, YC; Trinh, HT | 1 |
| Choi, HJ; Kim, DH; Kim, NJ; Kim, TW | 1 |
| Chen, MY; Guo, YP; Huang, WH; Rao, T; Shao, L; Zhang, W; Zhou, HH | 1 |
| Liu, FG; Zhang, WY; Zheng, YN | 1 |
| Dai, L; Hu, Y; Min, J; Qin, L; Xue, J; Zhang, J | 1 |
| Garza, DL; Greimel, P; Hanashima, S; Kinoshita, M; Matsumori, N; Murata, M; Umegawa, Y | 1 |
| Zhao, T | 1 |
33 other study(ies) available for ginsenoside rh2 and beta-escin
| Article | Year |
|---|---|
[Isolation and identification of 20(R)-ginsenoside-Rh2 (an anti-cancer constituent) from the fruits of Panax ginseng. C.A. Meyer].
Topics: Antineoplastic Agents, Phytogenic; Fruit; Ginsenosides; Panax; Plants, Medicinal; Saponins | 1991 |
Mechanism of action of ginsenoside Rh2: uptake and metabolism of ginsenoside Rh2 by cultured B16 melanoma cells.
Topics: Animals; Cell Cycle; Ginsenosides; Glycosylation; Melanoma, Experimental; Mice; Molecular Structure; Panax; Plants, Medicinal; Sapogenins; Saponins; Serum Albumin, Bovine; Triterpenes; Tumor Cells, Cultured | 1991 |
Inhibition of human ovarian cancer cell proliferation in vitro by ginsenoside Rh2 and adjuvant effects to cisplatin in vivo.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Cisplatin; Cystadenocarcinoma; Dose-Response Relationship, Drug; Female; Ginsenosides; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Ovarian Neoplasms; Saponins; Tumor Cells, Cultured | 1991 |
[Induction of phenotypic reverse transformation by plant glycosides in cultured cancer cells].
Topics: Cell Differentiation; Cell Division; Cell Membrane; Cell Transformation, Neoplastic; Chemical Phenomena; Chemistry; DNA, Neoplasm; Drugs, Chinese Herbal; Genes, ras; Ginsenosides; Humans; Melanins; Melanoma, Experimental; Panax; Plants, Medicinal; Saponins; Tumor Cells, Cultured | 1989 |
[Isolation and identification of the anti-tumor constituent, ginsenoside-Rh2].
Topics: Antineoplastic Agents, Phytogenic; Chemical Phenomena; Chemistry; Ginsenosides; Panax; Plants, Medicinal; Saponins | 1988 |
[Studies on new minor saponins isolated from leaves of Panax ginseng C. A. Meyer].
Topics: Chemical Phenomena; Chemistry; Drugs, Chinese Herbal; Ginsenosides; Panax; Plants, Medicinal; Saponins | 1987 |
Involvement of peanut agglutinin-binding sugar chains in experimental metastasis of B16 melanoma cells.
Topics: Animals; Carbohydrate Sequence; Ginsenosides; Glycoproteins; Lectins; Male; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Molecular Weight; N-Acetylneuraminic Acid; Neuraminidase; Peanut Agglutinin; Saponins; Sialic Acids | 1993 |
[Inhibitory effects of oral administration of ginsenoside Rh2 on tumor growth in nude mice bearing serous cyst adenocarcinoma of the human ovary].
Topics: Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Cisplatin; Cystadenocarcinoma, Serous; Female; Ginsenosides; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Ovarian Neoplasms; Saponins | 1993 |
Inhibitory effects by oral administration of ginsenoside Rh2 on the growth of human ovarian cancer cells in nude mice.
Topics: Administration, Oral; Animals; Drugs, Chinese Herbal; Female; Ginsenosides; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Ovarian Neoplasms; Panax; Plants, Medicinal; Saponins; Tumor Cells, Cultured | 1993 |
Ginsenoside-Rh1 and Rh2 inhibit the induction of nitric oxide synthesis in murine peritoneal macrophages.
Topics: Animals; Drugs, Chinese Herbal; Enzyme Induction; Ginsenosides; Interferon-gamma; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred C57BL; Nitric Oxide; Nitric Oxide Synthase; Panax; Peritoneal Cavity; Plants, Medicinal; Saponins | 1996 |
G1 phase-specific suppression of the Cdk2 activity by ginsenoside Rh2 in cultured murine cells.
Topics: 3T3 Cells; Animals; CDC2-CDC28 Kinases; Cells, Cultured; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinases; G1 Phase; Ginsenosides; Mice; Mice, Inbred BALB C; Protein Serine-Threonine Kinases; Saponins; Tumor Cells, Cultured | 1997 |
Ginsenoside-Rh2 blocks the cell cycle of SK-HEP-1 cells at the G1/S boundary by selectively inducing the protein expression of p27kip1.
Topics: Animals; Cell Cycle Proteins; COS Cells; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; DNA, Neoplasm; Down-Regulation; G1 Phase; Ginsenosides; HeLa Cells; Humans; Liver Neoplasms; Microtubule-Associated Proteins; Rats; Saponins; Tumor Cells, Cultured; Tumor Suppressor Proteins | 1996 |
Modulation of protein kinase C activity in NIH 3T3 cells by plant glycosides from Panax ginseng.
Topics: 3T3 Cells; Animals; Cell Division; Diglycerides; Ginsenosides; Glycosides; Mice; Panax; Plants, Medicinal; Protein Kinase C; Saponins; Type C Phospholipases | 1997 |
Activation of caspase-3 protease via a Bcl-2-insensitive pathway during the process of ginsenoside Rh2-induced apoptosis.
Topics: Apoptosis; Blotting, Western; Carcinoma, Hepatocellular; Caspase 3; Caspases; Cell Size; Cell Survival; Cysteine Endopeptidases; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Endopeptidases; Enzyme Activation; Enzyme Precursors; Flow Cytometry; Ginsenosides; Humans; Panax; Plants, Medicinal; Protease Inhibitors; Proto-Oncogene Proteins c-bcl-2; Saponins; Staurosporine; Transfection; Tumor Cells, Cultured | 1997 |
Properties of ginseng saponin inhibition of catecholamine secretion in bovine adrenal chromaffin cells.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Cardiac Glycosides; Catecholamines; Cattle; Central Nervous System Agents; Chromaffin Cells; Dose-Response Relationship, Drug; Ginsenosides; Glycyrrhizic Acid; Oleanolic Acid; Panax; Plants, Medicinal; Sapogenins; Saponins | 1998 |
Ginsenoside Rh2 and Rh3 induce differentiation of HL-60 cells into granulocytes: modulation of protein kinase C isoforms during differentiation by ginsenoside Rh2.
Topics: Antineoplastic Agents, Phytogenic; Cell Cycle; Cell Differentiation; Drugs, Chinese Herbal; Ginsenosides; Granulocytes; HL-60 Cells; Humans; Isoenzymes; Panax; Phosphorylation; Plants, Medicinal; Protein Kinase C; Proteins; Saponins; Tretinoin | 1998 |
Inhibitory effects of ginsenoside Rh2 on tumor growth in nude mice bearing human ovarian cancer cells.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cisplatin; Drugs, Chinese Herbal; Female; Ginsenosides; Humans; Killer Cells, Natural; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Ovarian Neoplasms; Saponins; Transplantation, Heterologous | 1998 |
Caspase 3 specifically cleaves p21WAF1/CIP1 in the earlier stage of apoptosis in SK-HEP-1 human hepatoma cells.
Topics: Amino Acid Sequence; Apoptosis; Base Sequence; Carcinoma, Hepatocellular; Caspase 3; Caspases; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinases; Cyclins; DNA Primers; Enzyme Activation; Enzyme Inhibitors; Ginsenosides; Humans; Hydrolysis; Liver Neoplasms; Molecular Sequence Data; Saponins; Sequence Homology, Amino Acid; Staurosporine; Tumor Cells, Cultured | 1998 |
[Differentiation of B16 melanoma cells induced by ginsenoside RH2].
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Division; Cell Transformation, Neoplastic; Ginsenosides; Melanins; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Panax; Plants, Medicinal; Saponins; Tumor Cells, Cultured | 1996 |
Anti-proliferating effects of ginsenoside Rh2 on MCF-7 human breast cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Carrier Proteins; CDC2-CDC28 Kinases; Cell Cycle Proteins; Cell Division; Cyclin D; Cyclin E; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinases; Cyclins; DNA-Binding Proteins; E2F Transcription Factors; E2F1 Transcription Factor; G1 Phase; Ginsenosides; Humans; Panax; Phosphorylation; Plants, Medicinal; Protein Serine-Threonine Kinases; Retinoblastoma Protein; Retinoblastoma-Binding Protein 1; Saponins; Transcription Factor DP1; Transcription Factors; Tumor Cells, Cultured | 1999 |
Ginsenoside RH-2 induces apoptotic cell death in rat C6 glioma via a reactive oxygen- and caspase-dependent but Bcl-X(L)-independent pathway.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Caspases; DNA Fragmentation; Enzyme Activation; Ginsenosides; Glioma; Immunoblotting; Oxidative Stress; Panax; Plants, Medicinal; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Reactive Oxygen Species; Saponins; Tetrazolium Salts; Thiazoles; Transfection; Tumor Cells, Cultured | 1999 |
Ginsenoside Rh2 induces apoptosis independently of Bcl-2, Bcl-xL, or Bax in C6Bu-1 cells.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Blotting, Western; Cell Survival; Ginsenosides; Microscopy, Electron; Panax; Plants, Medicinal; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Saponins; Time Factors; Tumor Cells, Cultured | 1999 |
Caspase 3-mediated cleavage of p21WAF1/CIP1 associated with the cyclin A-cyclin-dependent kinase 2 complex is a prerequisite for apoptosis in SK-HEP-1 cells.
Topics: Apoptosis; Caspase 3; Caspases; CDC2-CDC28 Kinases; Cell Cycle Proteins; Cyclin A; Cyclin E; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Cyclins; Endothelium, Vascular; Enzyme Activation; Ginsenosides; Humans; Kinetin; Microtubule-Associated Proteins; Mutation; Protein Serine-Threonine Kinases; Purines; Saponins; Tumor Cells, Cultured; Tumor Suppressor Proteins | 2000 |
Differential expression of protein kinase C subtypes during ginsenoside Rh2-lnduced apoptosis in SK-N-BE(2) and C6Bu-1 cells.
Topics: Animals; Apoptosis; Drugs, Chinese Herbal; Ginsenosides; Humans; Isoenzymes; Protein Kinase C; Rats; Saponins; Tumor Cells, Cultured | 2000 |
Anticarcinogenic effect and enhancement of metastatic potential of BALB/c 3T3 cells by ginsenoside Rh(2).
Topics: 3T3 Cells; Animals; Anticarcinogenic Agents; Apoptosis; CDC2-CDC28 Kinases; Cell Division; Cell Line, Transformed; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinases; Dose-Response Relationship, Drug; Ginsenosides; Methylcholanthrene; Mice; Mice, Nude; Neoplasm Metastasis; Neoplasm Transplantation; Oncogene Protein pp60(v-src); Protein Serine-Threonine Kinases; Saponins; Tumor Cells, Cultured | 2001 |
Transformation of ginseng saponins to ginsenoside Rh2 by acids and human intestinal bacteria and biological activities of their transformants.
Topics: Animals; Cell Line, Tumor; Cell Survival; Drug Evaluation, Preclinical; Feces; Ginsenosides; Helicobacter pylori; Humans; Hydrogen-Ion Concentration; Intestinal Mucosa; Intestines; Panax; Saponins; Temperature; Time Factors | 2004 |
Bifidus fermentation increases hypolipidemic and hypoglycemic effects of red ginseng.
Topics: Administration, Oral; Animals; Bifidobacterium; Cholesterol; Dose-Response Relationship, Drug; Fermentation; Ginsenosides; Hypoglycemia; Hypolipidemic Agents; Male; Mice; Mice, Inbred ICR; Panax; Phytotherapy; Plant Extracts; Plant Oils; Plant Roots; Polyethylene Glycols; Polysaccharides; Saponins; Surface-Active Agents; Triglycerides; Zea mays | 2007 |
Anxiolytic-like effects of ginsenosides Rg3 and Rh2 from red ginseng in the elevated plus-maze model.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Buspirone; Flumazenil; Ginsenosides; Male; Maze Learning; Mice; Panax; Phytotherapy; Piperazines; Plant Extracts; Plant Roots; Pyridines; Saponins | 2009 |
Quantification of Panax notoginseng saponins metabolites in rat plasma with in vivo gut microbiota-mediated biotransformation by HPLC-MS/MS.
Topics: Animals; Anti-Bacterial Agents; Biotransformation; Chromatography, High Pressure Liquid; Feces; Gastrointestinal Microbiome; Ginsenosides; Male; Panax notoginseng; Rats, Sprague-Dawley; Sapogenins; Saponins; Tandem Mass Spectrometry | 2019 |
[Synthesis and anti-tumor activity of ginsenoside Rh_2 caprylic acid monoester].
Topics: Animals; Caprylates; Ginsenosides; Mice; Molecular Structure; Neoplasms, Experimental; Saponins | 2019 |
Biocatalytic synthesis of ginsenoside Rh2 using Arabidopsis thaliana glucosyltransferase-catalyzed coupled reactions.
Topics: Arabidopsis; Batch Cell Culture Techniques; Biocatalysis; Biosynthetic Pathways; Drugs, Chinese Herbal; Ginsenosides; Glucosyltransferases; Panax; Sapogenins; Saponins; Triterpenes; Uridine Diphosphate | 2020 |
Behavior of Triterpenoid Saponin Ginsenoside Rh2 in Ordered and Disordered Phases in Model Membranes Consisting of Sphingomyelin, Phosphatidylcholine, and Cholesterol.
Topics: Cholesterol; Ginsenosides; Lecithins; Lipid Bilayers; Membrane Microdomains; Saponins; Sphingomyelins; Triterpenes | 2022 |
Suppression or Inhibition of VEGFs on Splenic Angiosarcoma Cell with Traditional Chinese Medicine Zhi Gan Cao.
Topics: Glycyrrhiza uralensis; Hemangiosarcoma; Humans; Medicine, Chinese Traditional; Saponins; Splenic Neoplasms; Vascular Endothelial Growth Factors | 2023 |