ginsenoside-rd has been researched along with vitexin* in 1 studies
1 other study(ies) available for ginsenoside-rd and vitexin
| Article | Year |
|---|---|
A NMR-Based Metabonomics Approach to Determine Protective Effect of a Combination of Multiple Components Derived from Naodesheng on Ischemic Stroke Rats.
Naodesheng (NDS) is a widely used traditional Chinese medicine (TCM) prescription for the treatment of ischemic stroke. A combination of 10 components is derived from NDS. They are: Notoginsenoside R1, ginsenoside Rg1, ginsenoside b1, ginsenoside Rd, hydroxysafflor yellow A, senkyunolide I, puerarin, daidzein, vitexin, and ferulic acid. This study aimed to investigate the protective effect of the ten-component combination derived from NDS (TCNDS) on ischemic stroke rats with a middle cerebral artery occlusion (MCAO) model by integrating an NMR-based metabonomics approach with biochemical assessment. Our results showed that TCNDS could improve neurobehavioral function, decrease the cerebral infarct area, and ameliorate pathological features in MCAO model rats. In addition, TCNDS was found to decrease plasma lactate dehydrogenase (LDH) and malondialdehyde (MDA) production and increase plasma superoxide dismutase (SOD) production. Furthermore, Topics: Animals; Apigenin; Brain; Brain Ischemia; Drugs, Chinese Herbal; Ginsenosides; Infarction, Middle Cerebral Artery; Isoflavones; L-Lactate Dehydrogenase; Magnetic Resonance Spectroscopy; Male; Malondialdehyde; Metabolomics; Oxidative Stress; Rats; Rats, Wistar; Stroke; Superoxide Dismutase | 2019 |