Compounds > ginkgolide b
Page last updated: 2024-08-24

ginkgolide b and 1-hexadecyl-2-acetyl-glycero-3-phosphocholine

ginkgolide b has been researched along with 1-hexadecyl-2-acetyl-glycero-3-phosphocholine in 471 studies

Research

Studies (471)

TimeframeStudies, this research(%)All Research%
pre-1990147 (31.21)18.7374
1990's254 (53.93)18.2507
2000's56 (11.89)29.6817
2010's14 (2.97)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Braquet, P; Sagach, VF; Zhukova, AV1
Desquand, S; Dumarey, C; Lefort, J; Vargaftig, BB1
Braquet, P; Kessels, GC; Nijkamp, FP; van Heuven-Nolsen, D1
Klöcking, HP1
Braquet, P; Hosford, D; Koltai, M1
Coëffier, E; Hidi, R; Vargaftig, BB1
de Lima, WT; Jancar, S; Sirois, P1
Braquet, P; Filep, JG; Földes-Filep, E; Hermán, F; Schneider, F1
Auclair, E; Braquet, P; Broquet, C; Chabrier, PE; Domingo, MT; Piro, F1
Rola-Pleszczynski, M; Thivierge, M1
Bahr, T; Grupe, R; Labes, D; Lohde, C1
Befus, AD; Davison, JS; Mathison, R1
Braquet, P; Capron, A; Joseph, M; Tran, A; Vanhée, D; Vorng, H1
Faden, AI; Tzendzalian, PA1
Doly, M; Droy-Lefaix, MT; Jung, H; Munz, K; Remé, C; Wei, Q1
Brochet, B; Dartigues, JF; Guinot, P; Henry, P; Loiseau, P; Orgogozo, JM1
Chao, W; Levine, BA; Olson, MS; Zhou, W1
Caramelo, C; Egido, J; Escanero, J; Gómez-Garre, D; González, E; Guerra, M; López-Farré, A; Riesco, A1
Ben-Efraim, S; Bonta, IL; Mozes, T1
Braquet, P; Huerta, JM; Montalescot, G; Zapol, WM1
Butler, KD; Crook, P; May, GR; Page, CP; Paul, W1
Northover, AM3
Analouei, AR; Corcoran, PC; Foegh, ML; Katz, NM; Rajan, SS; St Louis, JD; Wallace, RB; Wang, Y1
Arnoux, B; Canaud, B; Chavis, C; Cristol, JP; Damon, M; Mion, C1
Levine, BA; McCollum, MO; Olson, MS; Zhou, W1
Braquet, P; Koltai, M; Sipka, S; Szegedi, G1
Braquet, P; Kecskemeti, V1
Braillon, A; Cailmail, S; Champigneulle, B; Gaudin, C; Kleber, G; Lebrec, D1
Analouei, AR; Corcoran, PC; Foegh, ML; Katz, NM; Rajan, SS; Wallace, RB; Wang, Y1
Braquet, P; Broquet, C; Buisine, E; Esanu, A; Hosford, D; Koltai, M1
Coëffier, E; Joseph, D; Vargaftig, BB2
Hu, W; Kinnaird, AA; Man, RY1
He, Y; Hon, PM; Jiang, LM; Lee, CM; Shang, HS; Wong, HN1
Hofmann, B; Kertscher, HP; Lorenz, A; Ostermann, G1
Filep, JG; Fournier, A; Rousseau, A; Sirois, MG; Sirois, P1
Bazan, NG; Braquet, P; Clostre, F; Gaver, A; Miller, LG; Roy, RB1
Braquet, P; Guilbaud, J; Hosford, D; Koltz, P; Paubert-Braquet, M1
Braquet, P; Bueno, L; Droy-Lefaix, MT; Pons, L4
Gilfillan, AM; Hope, WC; Patel, BJ; Welton, AF; Wiggan, GA1
Barnes, PJ; Chung, KF; Evans, TW; Laurent, GJ; McAnulty, RJ; Rogers, DF1
Berti, F; Braquet, P; Rossoni, G1
Chao, W; Levine, BA; Olson, MS; Zhou, WG1
Ais, G; Braquet, P; Gomez-Garre, DN; López-Farre, A; López-Novoa, JM; Novo, C; Romeo, JM1
Braquet, P; Filep, JG; Mózes, T1
Barros, EJ; Boim, MA; Dos Santos, OF; Schor, N1
Braquet, P; Carrier, J; Jancar, S; Sirois, MG; Sirois, P1
Benveniste, J; Bidault, J; Jurgens, P; Leyravaud, S; Ninio, E1
Ben-Efraim, S; Bonta, IL; Heiligers, JP; Mózes, T; Saxena, PR; Tak, CJ; Zijlstra, FJ1
Peskar, BA; Pritze, S; Simmet, T1
Baskin, DG; Beck, JC; Braquet, P; Glidden, D; Goodner, CJ; Lernmark, A; Wilson, C; Wilson, D1
Calvo, IF; da Rocha, FA; de Falco, V; Fernandes, AJ; Jancar, S; Sirois, P1
Kulikov, VI; Muzia, GI1
Braquet, P; Carré, C; Lellouch-Tubiana, A; Mencia-Huerta, JM; Page, CP; Pfister, A; Pignol, B; Touvay, C; Vilain, B1
Fu, J; Li, PS; Yu, HP1
Becker, K; Förster, W; Lueddeckens, G; Rappold, R1
Braquet, P; Ferreira, MG; Fonteles, MC1
Braquet, P; Filep, J; Hermán, F1
Braquet, P; Dmitrieva, AV; Sagach, VF1
Braquet, P; Esanu, A; Hosford, D; Laurent, JP; Martin, C; Pommier, J; Rolland, A1
Bishai, I; Coceani, F; Hynes, N; Lees, J1
Menadue, MF; Oliver, JR; Rayner, TE1
Berdyshev, EV; Getmanova, OE1
Bozza, PT; Castro-Faria-Neto, HC; Cordeiro, RS; Correia-Da-Silva, AC; Martins, MA; Morhy, L; Sousa, MV1
Borgeat, P; Braquet, M; Braquet, P; Krump, E; McColl, SR; Naccache, PH; Poubelle, PE1
Tashjian, AH; Yang, JP1
Bartha, K; Jenei, B; Lázár, G; Medgyesi, GA1
Chakrabarty, S; Sheridan, DJ; Thomas, P1
Braquet, P; Hosford, D1
Hirafuji, M; Shinoda, H1
Ammit, AJ; O'Neill, C1
Bozza, PT; Cordeiro, RS; Faria Neto, HC; Martins, MA; Pasquale, CP; Pires, AL; Silva, PM1
Förster, W; Knospe, S; Köhler, E; Michaelis, D; Varnai, G; Wanka, H1
Braquet, P; Guilbaud, J; Hosford, D; Klotz, P; Paubert-Braquet, M1
Braquet, M; Egido, J; Gómez-Guerrero, C; González, E; Herrero-Beaumont, G; Maestre, C; Zarco, P1
Castro-Faria-Neto, HC; Cordeiro, RS; Henriques, MG; Martins, MA; Silva, PM; Silva, PS; Vargaftig, BB1
Heuer, H; Meade, CJ1
D'Souza, CJ; Krishnakantha, TP; Marathe, GK1
Hsieh, KH1
Chyczewski, L; Dabrowski, A; Gabryelewicz, A2
Cordeiro, RS; e Silva, PM; Faria Neto, HC; Martins, MA; Vargaftig, BB1
Conte, JV; Foegh, ML; Katz, NM; Wallace, RB1
Feuerstein, G; Gleason, MM; Hallenbeck, J; Yue, TL1
Braquet, P; Drouet, Y; Droy-Lefaix, MT; Geraud, G; Hosford, D1
Braquet, P; Plante, GE; Sirois, MG; Sirois, P1
Hofmann, B; Kertscher, HP; Ostermann, G; Till, U1
Evans, RW; Kochanek, PM; Magargee, MJ; Melick, JA; Nemoto, EM; Schoettle, RJ2
Myers, AK; Price, RM; Robey, JW1
Bauer, JA; Fritz, H; Hafner, M1
Chander, C; Desa, F; Howat, D; Moore, A; Willoughby, D1
Bahrami, S; Paul, E; Redl, H; Schiesser, A; Schlag, G; Thurnher, M; Vogl, C2
Braquet, P; Chabrier, PE; Lonchampt, MO; Mencia-Huerta, JM; Pignol, B1
Hauser, A; Heinroth-Hoffmann, I; Mest, HJ1
Blasquez, C; Braquet, P; Bunel, DT; Delarue, C; Delbende, C; Jégou, S; Vaudry, H1
Hecker, G; Ney, P; Schrör, K1
Bazan, NG; Braquet, P; Domingo, MT; Marcheselli, VL; Rossowska, MJ1
Granger, DN; Ibbotson, G; Kubes, P; Russell, J; Wallace, JL1
Braquet, P; Chabrier, PE; Domingo, MT; Hosford, DJ1
Bernabeu, F; Braquet, P; Gómez-Garre, D; López-Farré, A; López-Novoa, JM; Perez-Rodrigo, P; Ramón y Cajal, S1
DiSimone, AG; Earnest, MA; Fletcher, JR1
Amstutz, P; Guerin, B; Guidet, B; Maury, E; Offenstadt, G1
Csato, M; Dobozy, A; Judák, R; Kenderessy, AS1
Feuerstein, G; Lysko, PG; Yue, TL1
Braquet, P; Drouet, Y; Droy-Lefaix, MT; Géraud, G1
Befus, AD; Davison, JS; Mathison, R; Rimmer, C; Wallace, JL1
Braquet, P; Guilmard, C; Ivanow, F; Pirotzky, E; Principe, P; Sidoti, C1
Battistini, B; Braquet, P; Filep, JG; Sirois, P1
Krieglstein, J; Mennel, HD; Oberpichler, H; Rossberg, C; Sauer, D1
Braquet, P; Fecchio, D; Jancar, S; Russo, M; Sirois, P1
Finn, CA; Milligan, SR1
Bernabeu, F; Braquet, P; Gómez-Garre, D; López-Farré, A; López-Novoa, JM; Ramon y Cajal, S1
Braquet, P; Csató, M; Dobozy, A; Kemény, L1
Hogaboam, CM; McKnight, GW; Wallace, JL1
Braquet, P; Hénane, S; Mencia-Huerta, JM; Pignol, B; Rola-Pleszczynski, M; Sorlin, B1
Delpón, E; Diez, J; Tamargo, J1
Farber, NE; Gross, GJ; Jacob, HS; Maruyama, M; Vercellotti, GM1
Bentwich, Z; Eliraz, A; Fink, A; Geva, D; Konichezky, S; Zung, A1
Braquet, P; Cirino, M; Desquand, S; Lagente, V; Lefort, J; Randon, J; Touvay, C; Vargaftig, BB; Vilain, B1
Gustafson, KS; Jacob, HS; Nelson, RD; Vercellotti, GM; Yin, HQ1
Bigaud, M; Parratt, JR; Wainwright, CL2
Braquet, P; Etienne, A; Soulard, C; Thonier, F2
Braquet, P; Bricio, T; Cobo, ME; Egido, J; González, E; Hernando, L; Mampaso, FM; Martínez-Montero, JC; Pirotzky, E1
Chambers, E; Foegh, ML; Khirabadi, BS; Nakanishi, T; Ramwell, PW1
Csató, M; Dobozy, A; Kemény, L1
Kay, AB; Kurihara, K; Moqbel, R; Wardlaw, AJ1
Braquet, P; Jancar, S; Lauzière, M; Sirois, P; Thériault, P1
Ha, B; Jacob, HS; Raij, L; Tolins, JP; Vercellotti, GM; Wilkowske, M1
Braquet, P; Jancar, S; Sirois, P3
Beladi, I; Braquet, P; Farkas, G; Koltai, M; Mandi, Y1
Braquet, P; Chabrier, PE; Domingo, MT; Van Delft, JL; Van Haeringen, NJ; Verbeij, NL2
Braquet, P; Cluzel, J; Doly, M; Meyniel, G; Thierry, A1
Feuerstein, G; Sirén, AL1
Bernardini, R; Brucke, T; Calogero, AE; Chrousos, GP; Ehrlich, YH; Gold, PW1
Bruijnzeel, PL; Hamelink, ML; Kok, PT; Kreukniet, J; Warringa, RA1
Bruijnzeel, PL; Kok, PT; Warringa, RA1
Braquet, P; Koltai, M; Szekeres, L; Tosaki, A1
Beyer, CF; Hill, JM; Tepper, DJ1
Gallasch, M; Ignat'eva, VB; Kobrinskiĭ, EM; Kukushkin, NI; Vornovitskiĭ, EG1
Bienenstock, J; Hanglow, AC; Perdue, MH1
Atkinson, L; Coyle, AJ; Metzger, WJ; Page, CP; Sjoerdsma, K; Touvay, C1
Ernst, A; Mest, HJ; Riedel, A; Syka, J1
Adam, A; Bourdon, V; Damas, J; Remacle-Volon, G1
Braquet, P; Chabrier, PE; Chapelat, M; Viossat, I1
Braquet, P; Domingo, MT; Etienne, A; Martins, MA; Soulard, C1
Braquet, P; Chabrier, PE; Lagente, V; Mencia-Huerta, JM1
Cirino, G; De Nucci, G; MacNaughton, WK; McKnight, W; Wallace, JL1
Braquet, P; Etienne, A; Thonier, F1
Acker, G; Braquet, P; Mencia-Huerta, JM1
Barros, EJ; Boim, MA; Braquet, P; Bregman, R; dos Santos, OF; Draibe, SA; Pirotzky, E; Schor, N1
Dembinska-Kiec, A; Muller, MK; Peskar, BA; Peskar, BM1
Desquand, S; Lefort, J; Liu, FT; Mencia-Huerta, JM; Vargaftig, BB1
Braquet, P; Van Delft, JL; Van Haeringen, NJ; Verbey, NL1
Braquet, P; Colliez, P; Guilmard, C; Pirotzky, E1
Benveniste, J; Brink, C; Brunelleschi, S; Fantozzi, R; Giotti, A; Ledda, F; Renzi, D1
Dixon, EJ; Page, CP; Robertson, DN; Wilsoncroft, P1
Beck, G; Brzozowski, T; Drozdowicz, D; Garlicki, J; Konturek, SJ1
Braquet, P; Hosford, D; Koltai, M; Tosaki, A1
Beladi, I; Braquet, P; Farkas, G; Koltai, M; Mandi, Y; Mencia-Huerta, JM1
Bazan, NG; Braquet, P; Marcheselli, VL; Panetta, T1
Braquet, P; Lejeune, V; Mencia-Huerta, JM; Touvay, C; Vilain, B1
Bonavida, B; Braquet, P; Hosford, D; Paubert-Braquet, M1
Braquet, P; Chap, H; Feliste, R; Perret, B1
Braquet, P; Hénane, S; Mencia-Huerta, JM; Pignol, B1
Fouque, F; Parini, A; Schattner, M; Touqui, L; Vargaftig, BB1
Fauler, J; Frölich, JC; Sielhorst, G1
Bahr, T; Becker, K; Förster, W; Grupe, R; Lueddeckens, G; Schaper, U; Scheuch, DW1
Hoffmann, IH; Mentz, G; Mentz, P; Mest, HJ; Meyer, E; Riedel, A; Sperling, J; Tschorn, W1
Becker, K; Braquet, P; Förster, W; Lueddeckens, G1
Braquet, P; Chand, N; Howat, DW; Willoughby, DA1
Braquet, P; Filep, J; Mózes, T1
Barnes, PJ; Evans, TW; McCormack, DG1
Bittner, C; Lambrecht, G; Parnham, MJ1
Braquet, P; Chap, H; Douste-Blazy, L; Lamant, V; Mauco, G1
Cavero, I; Durand, G; Floch, A; James, C; Lave, D; Le Fur, G; Mondot, S; Pacot, D; Robaut, C; Sedivy, P1
Braquet, P; Filep, J; Földes-Filep, E1
Braquet, P; Etienne, A; Taylor, JE; Touvay, C; Vilain, B1
Bazan, NG; Braquet, P; Marcheselli, VL; Panetta, T; Spinnewyn, B1
Bazan, HE; Bazan, NG; Reddy, ST; Woodland, JM1
Bienvenu, P; Braquet, M; Ducousso, R; Gerasimo, P; Kergonou, JF; Lavaud, P; Mathieu, J1
Bazan, NG; Birkle, DL; Braquet, P; Kurian, P1
Dusting, GJ; Stewart, AG1
Benveniste, J; Bidault, J; Korth, R; Nunez, D1
Bourgain, RH; Braquet, P; Etienne, A; Lefort, J; Touvay, C; Vargaftig, BB1
Braquet, P; Sirois, P; Soufir, M; Touvay, C; Vilain, B1
Abisogun, AO; Braquet, P; Tsafriri, A1
Braquet, P; Filep, J; Hermán, F; Mózes, T1
Braquet, P1
Andries, R; Bourgain, RH; Braquet, P1
Braquet, P; De Giaccobi, G; Jancar, S; Mariano, M; Mencia-Huerta, JM; Sirois, P1
Braquet, P; Chap, H; Douste-Blazy, L; Lachachi, H; Plantavid, M; Simon, MF1
Braquet, P; Desquand, S; Etienne, A; Lagente, V; Lefort, J; Maridonneau-Parini, I; Randon, J; Touvay, C; Vargaftig, BB; Vilain, B1
Borgeat, P; Braquet, P; Etienne, A; Sirois, P; Touvay, C; Vilain, B1
Baggiolini, M; Dewald, B2
Hwang, SB; Lam, MH1
Baroggi, N; Braquet, P; Etienne, A1
Agrawal, DK; Suliaman, FA; Tamura, N; Townley, RG1
Braquet, P; Hébert, RL; Plante, GE; Sirois, P1
Piper, PJ; Stewart, AG1
Bureau, M; Joseph, D; Vargaftig, BB1
Bonhomme, B; Braquet, P; Chabrier, PE; Doly, M; Meyniel, G1
Braquet, P; Clostre, F; Etienne, A; Mencia-Huerta, JM1
Becker, K; Braquet, P; Förster, W1
Benveniste, J; Braquet, P; Chignard, M; Korth, R; Le Couedic, JP; Norel, X; Nunez, D; Spinnewyn, B1
Borgeat, P; Braquet, P; Harczy, M; Maclouf, J; Pradelles, P; Sirois, P1
Berti, F; Braquet, P; Omini, C; Rossoni, G1
Adnot, S; Joseph, D; Vargaftig, BB1
Braquet, P; Neuwirth, R; Satriano, JA; Schlondorff, D; Singhal, P1
Acker, G; Braquet, P; Etienne, A; Hecquet, F; Mencia-Huerta, JM1
Myers, AK; Nakanishi, T; Ramwell, P1
Braquet, P; Cano, E; Fernandez-Gallardo, S; Sanchez Crespo, M1
Bazan, HE; Bazan, NG; Braquet, P; Reddy, ST1
Wallace, JL1
Fortes, ZB; Garcia-Leme, J; Lagente, V; Vargaftig, BB1
Bosia, A; Braquet, P; Bussolino, F; Camussi, G; Prosdocimi, M; Tessari, F; Turrini, F1
Braquet, P; Plante, GE; Sirois, P1
Braquet, P; Jancar, S; Plante, GE; Sirois, MG; Sirois, P1
Berti, F; Magni, F; Rossoni, G1
Dembińska-Kieć, A; Peskar, BA; Peskar, BM1
Braquet, P; Henane, S; Mencia-Huerta, JM; Pignol, B; Pirotzky, E1
Lagente, V; Steel, G; Vargaftig, B; Wallace, JL; Whittle, BJ1
Braquet, P; Hénane, S; Mencia-Huerta, JM; Pignol, B; Rola-Pleszczynski, M1
Bourgain, RH; Braquet, P1
Braquet, P; Guinot, P; Touvay, C1
Imai, T; Jacob, HS; Moldow, CF; Vercellotti, GM; Weir, EK1
Braquet, P; Colliez, P; Guilmard, C; Mencia-Huerta, JM; Pirotzky, E; Schaeverbeke, J1
Csatò, M; Czarnetzki, BM1
Braquet, P; Coyle, AJ; Page, CP; Touvay, C; Urwin, SC; Villain, B1
Braquet, P; Etienne, A; Hecquet, F1
Benveniste, J; Denizot, Y; Dubertret, L; Jean-Louis, F; Michel, L; Pitton, C; Thomas, Y1
Benveniste, J; Korth, R1
Bazan, N; Blavet, N; Braquet, P; Clostre, F; Spinnewyn, B1
Braquet, P; Mest, HJ; Riedel, A1
Braquet, P; Pignol, B; Pouliot, C; Rola-Pleszczynski, M1
Braquet, P; Clostre, F; Etienne, A; Hecquet, F; Soulard, C; Spinnewyn, B1
Braquet, P; Foegh, ML; Khirabadi, BS; Ramwell, PW; Rowles, JR1
Adnot, S; Braquet, P; Lefort, J; Vargaftig, BB1
Braquet, P; Chap, H; Douste-Blazy, L; Simon, MF1
Braquet, P; Etienne, A; Guilmard, C; Hecquet, F; Soulard, C1
Bonhomme, B; Braquet, P; Doly, M; Meyniel, G1
Braquet, P; Feuerstein, G; Leader, P; Siren, AL1
Braquet, P; Etienne, A; Touvay, C1
Braquet, P; Caramelo, C; Fernandez-Gallardo, S; Lopez-Novoa, JM; Sanchez Crespo, M; Sanz, E; Villamediana, LM1
Braquet, P; Garay, R1
Auguet, M; Baranes, J; Braquet, P; Chabrier, PE; Hellegouarch, A; Le Hegarat, M; Viossat, I1
Cirino, M; Lagente, V; Lefort, J; Vargaftig, BB1
Andries, R; Bourgain, RH; Braquet, P; Maes, L1
Filep, J; Frölich, JC; Küster, LJ1
Braquet, P; Desquand, S; Lagente, V; Lefort, J; Randon, J; Touvay, C; Vargaftig, BB; Vilain, B1
Fernandez-Gallardo, S; Inarrea, P; Nieto, ML; Sanchez Crespo, M1
Adnot, S; Braquet, P; Lagente, V; Lefort, J; Vargaftig, BB1
Dideberg, O; Dupont, L; Germain, G1
Braquet, P; Clostre, F; Etienne, A; Hecquet, F; Soulard, C; Touvay, C1
Braquet, P; Chabrier, E; Koltai, M; Lepran, I; Szekeres, L; Viossat, I1
Baranès, J; Braquet, P; Fernández-Gallardo, S; Nieto, ML; Sánchez-Crespo, M1
Andries, R; Bourgain, RH; Braquet, M; Braquet, P; Maes, L; Touqui, L1
Balogh, I; Kecskemeti, V3
Van Dijk, JP; Wilson, JH; Zijlstra, FJ1
Aglietta, M; Arese, M; Bussolino, F; Camussi, G; Costamagna, C; Garbarino, G; Pescarmona, G; Sanavio, F; Silvagno, F; Soldi, R1
Davison, JS; Mathison, R1
Alonso, R; Arévalo, M; Calvo, JJ; García, LJ; López-Novoa, JM; Montero, A; Rodríguez-Nodal, F; Sánchez-Vicente, C1
Autore, G; Capasso, F; Di Carlo, G; Di Urno, MV; Izzo, AA; Mascolo, N1
Arriba, G; Caramelo, C; Lamas, S; López-Novoa, JM; Olivera, A; Rodriguez-Barbero, A; Rodriguez-Puyol, D; Schrier, RW1
Abdo, EE; Bonizzia, A; Coelho, AM; Jancar, S; Kwasniewski, FH; Machado, MC; Sampietre, SN1
Domańska-Janik, K; Zabłocka, B1
Braquet, P; Butterly, DW; Coffman, TM; Pirotzky, E; Ruiz, P; Spurney, RF1
Berdyshev, EV; Vaschenko, MA; Vaskovsky, VE1
Bozzaro, S; Malchow, D; Schaloske, R; Sordano, C1
Aguilera, JG; Croxatto, HB; Velasquez, LA1
Gonzalez-Sarmiento, R; López-Novoa, JM; Rodriguez-Barbero, A; Rodriguez-Lopez, AM1
Arnoux, B; Cornu, E; Denizot, Y; Feiss, P; Laskar, M; Mercury, P; Nathan, N1
Birkle, DL; Sheng, Y1
Barrigón, S; Fernandez-Gallardo, S; Fernandez-Sanpablo, R; Perez, MD; Salinas, P; Sanchez-Crespo, M1
Denizot, Y; Nathan, N1
Braquet, P; Dobozy, A; Duda, E; Hunyadi, J; Kenderessy, AS1
Domańska-Janik, K; Zabøocka, B1
Isselhard, W; Minor, T; Yamaguchi, T2
Bazan, NG; Da Silva, RC; Ferreira, MB; Fin, C; Izquierdo, I; Jerusalinsky, D; Medina, JH; Quillfeldt, JA; Schmitz, PK1
Bueno, L; Delvaux, M; Frexinos, J; Jeanneton, O1
Diserbo, M; Fatome, M; Lalouette, F; Martin, C; Verdetti, J1
Ji, Z; Li, S; Wang, B2
Braquet, P; Koltai, M; Pirotzky, E1
Brunet, F; Dhainaut, JF; Mira, JP1
Flores, NA; Goulielmos, NV; Seghatchian, MJ; Sheridan, DJ1
Bieńkiewicz, A; Dabrowski, R; Kuś, E; Pajszczyk-Kieszkiewicz, T1
László, F; Moncada, S; Whittle, BJ1
Brochet, B; Confavreux, C; Guinot, P; Lavergne, V; Orgogozo, JM; Rumbach, L1
Dikshit, M; Kumari, R; Seth, P; Srimal, RC1
Fang, GD; Fonteles, MC; Guerrant, RL; Thielman, NM1
Bazan, NG; Da Silva, RC; Ferreira, MB; Fin, C; Izquierdo, I; Jerusalinsky, D; Medina, JH; Quillfeldt, JA; Schmitz, PK; Walz, R1
Dhainaut, JF; Dreyfuss, D; Holzapfel, L; Le Tulzo, Y; Mira, JP; Schlemmer, B; Solet, JP; Tenaillon, A; Wolff, M; Zeni, F1
Liu, BJ; Zhang, HT; Zheng, MR1
Blasevich, M; Colombo, C; Galella, G; Galli, C; Papini, N; Petroni, A; Salami, M1
Grino, JM1
Cury, Y; Jancar, S; Oga, S; Teixeira, CF1
Blanchet, F; Carbon, C; Guilmard, C; Hanslik, T; Nochy, D; Pirotzky, E; Seta, N1
Krieglstein, J; Prehn, JH1
van Delft, JL; van Haeringen, NJ; Verbey, NL1
Bazan, NG; Clark, GD; Kato, K; Zorumski, CF1
Bouman, AA; Mulder, MF; Scheffer, PG; Thijs, LG; van den Bos, GC; van Kraats, AA; van Lambalgen, AA1
Egido, J; Gómez-Chiarri, M; González, E; Lerma, JL; López-Armada, MJ; Mampaso, F; Ortíz, A1
Bazan, NG; Cohen, RA; Gebhardt, BM1
Tsai, JJ; Wang, SR; Yu, LN1
Guo, ZM; Liu, CT; Peters, CJ; Qian, C1
Isselhard, W; Minor, T1
Diéz Marques, ML; Duque, I; Gonzalez-Rubio, M; Rodriguez Puyol, D; Rodriguez Puyol, M; Ruiz, P1
Chopra, K; Ganguly, NK; Gupta, S; Singh, M1
de Matos, IM; Freire-Maia, L1
Analouei, AR; Corcoran, PC; Foegh, ML; Katz, NM; St Louis, JD; Tse, SS; Wallace, RB; Wang, Y1
Jancar, S; Russo, M; Vásquez-Bravo, YL1
Chen, ZN1
Levine, BA; Olson, MS; Zhou, W1
Badosa, F; Bulbena, O; Closa, D; Fernández-Cruz, L; Gelpi, E; Hotter, G; Morris, M; Pi, F; Roselló-Catafau, J1
Christopherson, TJ; Hofer, RE; Lanier, WL; Milde, JH; Scheithauer, BW1
Alsina, J; Bordalba, JR; Carrera, M; Griño, JM; Martinez-Castelao, A; Moliner, R; Seron, D; Torras, J; Valles, J1
Ambrosio, G; Buja, LM; Chiariello, M; Condorelli, M; Golino, P; McNatt, J; Oriente, A; Pascucci, I; Ragni, M; Triggiani, M1
Borobia, FG; Escriba, JM; Fabregat, J; Farran, L; Figueras, J; Jaurrieta, E; Rafecas, A; Torras, J1
Chang, YL; Chen, IS; Huang, TF; Ishii, H; Ko, FN; Teng, CM; Yu, SM1
Bozza, PT; Castro Faria Neto, HC; Cordeiro, RS; e Silva, PM; Lima, MC; Martins, MA; Vargaftig, BB1
Becker, K; Förster, W; Grupe, R; Lueddeckens, G1
Bidault, J; Maiza, H; Ninio, E1
Braquet, P; Jager, GV; van Delft, JL; van Haeringen, NJ; Verbeij, NL1
Endo, S; Hirashima, Y; Karasawa, K; Nojima, S; Otsuji, T; Takaku, A1
Chyczewski, L; Debek, W; Gruca, A; Gruca, P1
Chyczewski, L; Debek, W; Kirejczyk, JK1
Chyczewski, L; Debek, W; Dziecioł, J; Kirejczyk, JK; Makarewicz, M; Nikliński, J1
Hackett, D; O'Gorman, DJ; Shahi, M; Sheridan, DJ; Siminiak, T1
Baltatu, O; Brailoiu, E; Branisteanu, DD; Costuleanu, M; Filipeanu, CM; Nechifor, M; Saila, L; Slatineanu, S1
Bernard, H; Boisseau, M; Casadebaig, F; Dupin, JP; Gravier, D; Hou, G1
Ais, G; López-Farré, A; López-Novoa, JM; Novo, C; Pérez-Barriocanal, F; Romeo, JM1
de Abreu Castro, MS; Dias, MF; Farinelli, P; Ferreira-Alves, DL; Francischi, JN; Kiyomi Funayama Tatsuo, MA; Pacheco, CM; Rocha, OA; Sirois, P1
Arnoux, B; Cornu, E; Denizot, Y; Feiss, P; Laskar, M; Lathelize, M; Mercury, P; Nathan, N1
Aupetit, B; Baghos, W; Bagnis, C; Braquet, P; Deray, G; Dubois, M; Jacobs, C; Jacquiaud, C; Pirotzky, E1
Darlington, CL; Maclennan, K; Smith, PF1
Dong, JC; Li, M; Shi, ZY1
De Kimpe, SJ; Thiemermann, C; Vane, JR1
Chen, W; Cheng, D2
Jia, L; Xiao, J; Zhao, D1
Fischbarg, J; Kang, F; Kuang, K; Li, J; Zhu, Z1
Xiao, J; Zao, D; Zhen, H1
Aïssa, J; Arnoux, B; Benveniste, J; Nathan, N1
Braquet, P; Gukovskaya, A; Gukovsky, S; Pandol, SJ; Poucell-Hatton, S; Reavey, P; Sandoval, D; Sisk, A1
Chignard, M; Paulin, D; Renesto, P; Vicart, P1
Araújo, C; Catelli, M; Cordeiro, R; Estato, V; Lopes-Martins, R; Tibiriçá, E1
Bazan, NG; Packard, MG; Teather, LA1
Barks, JD; Eun, BL; Liu, XH; Silverstein, FS1
Alsina, J; Cruzado, JM; Grinyo, JM; Herrero, I; Paubert-Braquet, M; Riera, M; Torras, J; Valles, J1
Closa, D; Gelpí, E; Hotter, G; Pi, F; Prats, N; Roselló-Catafau, J1
Collins, LC; Roberts, AM1
Fang, GD; Guerrant, RL; Marcinkiewicz, M; Sarosiek, J; Thielman, NM1
Araújo, CV; Cordeiro, RS; Estato, V; Lopes-Martins, RA; Moreira, S; Tibiriçá, EV1
Endo, S; Hirashima, Y; Nogami, K; Takaku, A1
Lash, GE; Legge, M1
Bazan, HE; Tao, Y1
Bezerra, LR; Guerrant, RL; Lima, AA; Lyerly, DM; Maia, ME; Ribeiro, RA; Rocha, MF1
Chen, W; Li, S; Liu, B; Zhang, H1
Edelman, ER; Sirois, MG1
Cornu, E; Denizot, Y; Dulery, C; Dupuis, F; Praloran, V; Rougier, F1
López-Novoa, JM; Martínez-Salgado, C; Pérez de Lema, G; Rodríguez-Barbero, A; Rodríguez-Puyol, D1
Antonopoulou, S; Argyropoulos, D; Avramopoulou, V; Demopoulos, CA; Froussios, C1
Larsen, R; Pizanis, A; Rose, S; Silomon, M1
Bix, GJ; Clark, GD2
Li, CL; Wong, YY1
De Matos, IM; Freire-Maia, L; Leite, R; Rocha, OA1
Francescangeli, E; Goracci, G; Grassi, S; Pettorossi, VE1
Gozal, D; Graff, GR; Holt, GA; Torres, JE1
Alsina, J; Condom, E; Cruzado, JM; Grinyó, JM; Herrero, I; Lloberas, N; Martorell, J; Riera, M; Torras, J1
Jiménez, A; López-Novoa, JM; Martín, T; Montero, A; Pérez-Arellano, JL; Sánchez, ML1
Chen, JZ; Chen, KX; Chen, ZL; Gu, JD; Hu, LH; Ji, RY; Jiang, HL; Zhu, WL1
Damas, P; de Vathaire, F; Dhainaut, JF; Gourlay, ML; Guinot, P; Hemmer, M; Holzapfel, L; Le Tulzo, Y; Mira, JP; Radermacher, P; Schaller, MD; Sollet, JP; Tenaillon, A; Vedrinne, JM; Wolff, M; Zeni, F1
Akiba, S; Hashizume, T; Kawauchi, T; Oka, T; Sato, T1
Huang, TF; Hung, WC; Ko, WC; Lee, LW; Lin, CH; Peng, HC; Sheu, JR; Su, CH; Yen, MH1
Dong, JC; Li, M; Wu, GT1
Hou, T; Wu, K; Xiao, J; Zeng, H; Zhao, D1
Timlioglu, O; Uluoglu, C1
Li, S; Meng, Q; Zhang, L1
Albini, A; Biancone, L; Boccellino, M; Bussolati, B; Camussi, G; Cantaluppi, V; Conaldi, PG; Del Sorbo, L; Toniolo, A1
Kato, K1
Goldman, R; Moshonov, S; Zor, U1
Yao, X; Yu, R; Zhang, H; Zhao, H; Zheng, Y1
Tremblay, G1
Boichot, E; Braquet, P; Carre, C; Guinot, P; Lagente, V; Mencia-Huerta, JM1
Chen, Z; Hu, L; Jiang, Y; Xie, Y; Zhen, H1
James, AN; Parkman, HP; Ryan, JP1
Sun, GY; Wang, JH1
Chyczewski, L; Dlugosz, JW; Gabryelewicz, A; Siemiatkowski, A; Wereszczynska-Siemiatkowska, U1
Bach, A; Gebhard, MM; Martin, E; Schmidt, H; Schmidt, W; Walther, A; Yilmaz, N1
Franke, U; Grote, M; Oppelt, P; Schaefers, HJ; Wahlers, T; Wittwer, T1
Harrison, KA; Marathe, GK; McIntyre, TM; Morrow, JD; Murphy, RC; Prescott, SM; Roberts, LJ; Tjoelker, LW; Zimmerman, GA1
Chen, ZL; Hu, LH; Xie, YY1
Chatterjee, SS; Kondratskaya, EL; Krishtal, OA; Lishko, PV1
Bozza, MT; Bozza, PT; Caiado, LF; Castro-Faria-Neto, HC; de Assis, EF; Marathe, GK; McIntyre, TM; Prescott, SM; Silva, AR; Zimmerman, GA1
Borobia, FG; Busquets, J; Castellvi, J; Fabregat, J; Figueras, J; Fradera, R; Herrero, I; Jaurrieta, E; Jorba, R; Torras, J1
Carlson, SL; Hostettler, ME; Knapp, PE1
Kolaczkowska, E; Plytycz, B; Seljelid, R; Shahzidi, S; van Rooijen, N1
Jaracz, S; Nakanishi, K; Strømgaard, K1
Lee, RK; Teather, LA; Wurtman, RJ1
Chen, ZH; Hao, XJ; Li, L; Shen, YM; Shen, ZQ; Yang, XS; Zuo, GY1
Ishii, S; Nakanishi, K; Saito, DR; Shimizu, T; Shindou, H; Strømgaard, K1
Magnusson, JE; Teather, LA; Wurtman, RJ1
Bazan, NG; Bernatchez, PN; Gélinas, DS; Rollin, S; Sirois, MG1
Abal, AT; Abul, HT; Haines, DD; Mahmoud, FF; Wise, JA1
Bazan, NG; Diemer, NH; Kolko, M; Rodriguez de Turco, EB1
Ishii, S; Jaracz, S; Nakanishi, K; Shimizu, T; Shindou, H; Strømgaard, K; Suehiro, M; Vogensen, SB1
Nie, ZG; Wang, WJ1
Kishore, K; Saraf, MK; Sharma, A; Singh, M; Thomas, KM1
Chatterjee, SS; Kondratskaya, EL; Krishtal, OA1
Ivanov, AI; Kulchitsky, VA; Patel, S; Romanovsky, AA1
Chatterjee, SS; Kondratskaya, EL; Krishtal, OA; Lalo, UV; Pankratov, YV1
Tao, YX; Xu, Y1
Gandhi, CR; Harvey, SA; Nemoto, EM; Subbotin, VM; Yang, Y1
Burgos, RA; Folch, H; Hancke, JL; Hermosilla, R; Hidalgo, MA; Matthei, SM1
Bazan, NG; DeCoster, MA; Zhu, P1
Bredt, DS; Hua, Z; Johns, RA; Tao, YX; Xu, Y; Zhang, B1
Bazan, H; Ma, X; Ni, CX; Sun, HC1
Egresits, J; Kordás, K; László, F; László, FA; Morschl, E; Nemcsik, J; Pávó, I1
Arai, H; Bennett, SA; Bonin, F; Franks, DJ; Lallier, J; Migahed, L; Mo, F; Ryan, SD1
Nie, ZG; Peng, SY; Wang, WJ1
Hatakeyama, M; Imaizumi, T; Ishikawa, A; Kimura, H; Metoki, N; Sakaki, H; Sato, Y; Satoh, K; Taima, K; Tanji, K; Yamashita, K; Yoshida, H1
Chen, XH; Liao, WH; Ou-Yang, XY; Wang, WJ1
Damaj, BB; Jin, Y; Maghazachi, AA1
McLarnon, JG; Ryu, JK; Tran, KC1
Basilico, F; Bombardelli, E; De Palma, A; Mauri, P; Morazzoni, P; Pozzi, F; Riva, A; Rossoni, G1
Ozturk, H; Yagmur, Y1
Dong, K; Feng, YY; Han, J; Ma, XM; Su, SH; Wang, CP; Xiang, Y; Yang, YP1
Feng, YY; Han, J; Lu, YY; Ma, XM; Su, SH; Wang, CP; Xiang, Y; Yang, YP1
Liu, CY; Lu, QJ; Sun, M; Wang, LJ1
Liu, Y; Ou-Yang, XY; Peng, SY; Wang, WJ; Zhang, FY1
Mao, YJ; Wang, L; Wang, WJ1
Arthur, JR; McLeod, E; Sneddon, AA; Wahle, KW1
Barreto-de-Souza, V; Bou-Habib, DC; Bozza, PT; Castro-Faria-Neto, HC; Lima, RG; Moreira, L; Paes-Leme, J1
Chen, G; Chen, K; Gui, C; Jiang, H; Liew, OW; Luo, X; Puah, CM; Zhu, W1
Di, Y; Hu, CX; Xia, GD; Xia, SH; Zhao, ZL1
Li, SQ; Yang, LJ; Zhang, Y1
Chen, MF; Ding, WL; Gu, HY; Hu, JJ; Liu, WC1
Chin, TK; Hofmann, PA; Leary, PJ; Morrison, RR; Rajasekaran, S; Tuomanen, EI1
Di, Y; Tong, CQ; Xia, SH1
Brito, GA; Cunha, FQ; Justino, PF; Lima-Junior, RC; Mota, JM; Ribeiro, RA; Soares, PM; Souza, MH1
Faez, S; Frimmel, SA; Garland, RC; Hafezi-Moghadam, A; Nakao, S; Schering, A; Sun, D; Tayyari, F; Xie, F; Zandi, S1
Liao, WH; Liu, Y; Nie, ZG; Peng, SY; Wang, F; Wang, L; Wang, WJ1
Jiao, HY; Suo, QL; Zhang, XT2
He, S; Mo, YZ; Wei, JF; Wei, XL; Yang, H1
Chen, K; Xia, SH; Xiang, XH; Xu, W1
Bao, L; Chen, B; Liu, X; Qi, R; Yan, Y; Zhao, Y1
He, X; He, Z; Hu, J; Ke, J; Lan, P; Li, S; Lian, L; Sun, L; Wu, X; Zou, Y1
Huang, HM; Huang, JF; Wang, ZJ; Yang, YF; Yao, Y; Zhao, HP1
Fang, X; Guan, CX; Hua, R; Pei, HX1
Cao, L; Cao, ZY; Luo, YP; Wang, ZZ; Xiao, W; Zhang, H; Zhang, XZ1
Cao, L; Xiao, BG; Xiao, W; Yu, WB; Zhao, YY1
Kispert, S; Marentette, J; McHowat, J1

Reviews

14 review(s) available for ginkgolide b and 1-hexadecyl-2-acetyl-glycero-3-phosphocholine

ArticleYear
Recent progress in ginkgolide research.
    Medicinal research reviews, 1991, Volume: 11, Issue:3

    Topics: Animals; Diterpenes; Ginkgolides; Lactones; Models, Molecular; Molecular Structure; Plant Extracts; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Research

1991
[Phospholipid thrombocyte activating factor, its analogs and antagonists: prospects of their use in medicine].
    Vestnik Akademii meditsinskikh nauk SSSR, 1991, Issue:10

    Topics: Azepines; Diterpenes; Fibrinolytic Agents; Ginkgolides; Humans; In Vitro Techniques; Lactones; Lysophosphatidylcholines; Platelet Activating Factor; Platelet Activation; Platelet Aggregation; Platelet Function Tests; Thrombosis; Triazoles

1991
From ginkgolides to N-substituted piperidino-thieno diazepines, a new series of highly potent dual antagonists.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1991, Volume: 21B

    Topics: Animals; Azepines; Diterpenes; Ginkgolides; Humans; Lactones; Piperidines; Plant Extracts; Platelet Activating Factor; Tetrazoles; Thienopyridines; Triazoles

1991
Ethnopharmacology and the development of natural PAF antagonists as therapeutic agents.
    Journal of ethnopharmacology, 1991, Volume: 32, Issue:1-3

    Topics: Diterpenes; Ethnology; Ginkgolides; Humans; In Vitro Techniques; Lactones; Pharmacology; Plants, Medicinal; Platelet Activating Factor

1991
PAF antagonism as an approach to the treatment of airway hyperreactivity.
    The American review of respiratory disease, 1991, Volume: 143, Issue:3 Pt 2

    Topics: Allergens; Animals; Asthma; Azepines; Bronchoconstriction; Diterpenes; Ginkgolides; Humans; Lactones; Platelet Activating Factor; Triazoles

1991
Platelet-activating factor. A putative mediator in central nervous system injury?
    Stroke, 1990, Volume: 21, Issue:11 Suppl

    Topics: Animals; Brain; Cerebrovascular Disorders; Diterpenes; Gerbillinae; Ginkgolides; Lactones; Platelet Activating Factor; Rats; Signal Transduction

1990
Interactions of arachidonic acid metabolites and platelet activating factor and mechanism of action in hypersensitivity reactions.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 1987, Volume: 20, Issue:5

    Topics: Animals; Arachidonic Acids; Dinoprostone; Diterpenes; Eicosanoic Acids; Enzyme Activation; Ginkgolides; Guinea Pigs; Hypersensitivity; Inflammation; Lactones; Leukotriene B4; Lung; Muscle Contraction; Phospholipases; Phospholipases A; Platelet Activating Factor; Prostaglandins E; SRS-A; Thromboxane B2

1987
Proofs of involvement of PAF-acether in various immune disorders using BN 52021 (ginkgolide B): a powerful PAF-acether antagonist isolated from Ginkgo biloba L.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1986, Volume: 16

    Topics: Anaphylaxis; Animals; Bronchial Spasm; Diterpenes; Ginkgolides; Graft Rejection; Hemodynamics; Humans; Immune System Diseases; In Vitro Techniques; Kidney Diseases; Lactones; Leukocytes; Plant Extracts; Platelet Activating Factor; Platelet Aggregation; Shock; Thrombosis

1986
Anti-anaphylactic properties of BN 52021: a potent platelet activating factor antagonist.
    Advances in experimental medicine and biology, 1987, Volume: 215

    Topics: Anaphylaxis; Animals; Antigens; Diterpenes; Ginkgolides; In Vitro Techniques; Lactones; Lung; Plant Extracts; Platelet Activating Factor

1987
The role of PAF-acether in anaphylaxis demonstrated with the use of the antagonist BN 52021.
    Agents and actions. Supplements, 1987, Volume: 21

    Topics: Anaphylaxis; Animals; Diterpenes; Ginkgolides; Humans; Lactones; Lung; Plant Extracts; Platelet Activating Factor; T-Lymphocytes

1987
PAF-cytokine autocatalytic feed-back network in septic shock: involvement in acute renal failure.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1994, Volume: 9 Suppl 4

    Topics: Acute Kidney Injury; Animals; Azepines; Cytokines; Diterpenes; Down-Regulation; Feedback; Ginkgolides; Humans; Lactones; Lipopolysaccharides; Platelet Activating Factor; Shock, Septic; Triazoles

1994
Platelet-activating factor antagonists as therapeutic strategy in sepsis.
    Progress in clinical and biological research, 1994, Volume: 388

    Topics: Animals; Clinical Trials as Topic; Disease Models, Animal; Diterpenes; Endotoxins; Ginkgolides; Hemodynamics; Humans; Lactones; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Sepsis; Shock, Septic

1994
[Recent progress in the study of anti-PAF (platelet activating factor) constituents of medicinal herbs].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 1993, Volume: 18, Issue:6

    Topics: Animals; Asthma; Benzofurans; Diterpenes; Drugs, Chinese Herbal; Furans; Ginkgolides; Humans; Lactones; Lignans; Plant Extracts; Platelet Activating Factor

1993
The neuroprotective properties of the Ginkgo biloba leaf: a review of the possible relationship to platelet-activating factor (PAF).
    Journal of ethnopharmacology, 1996, Volume: 50, Issue:3

    Topics: Animals; Cerebrovascular Circulation; Dementia; Diterpenes; Free Radical Scavengers; Ginkgo biloba; Ginkgolides; Humans; Lactones; Memory; Neuroprotective Agents; Plant Extracts; Plant Leaves; Platelet Activating Factor; Trees

1996

Trials

11 trial(s) available for ginkgolide b and 1-hexadecyl-2-acetyl-glycero-3-phosphocholine

ArticleYear
[Pilot study of Ginkgolide B, a PAF-acether specific inhibitor in the treatment of acute outbreaks of multiple sclerosis].
    Revue neurologique, 1992, Volume: 148, Issue:4

    Topics: Adult; Diterpenes; Female; Ginkgolides; Humans; Lactones; Male; Multiple Sclerosis; Neurologic Examination; Pilot Projects; Platelet Activating Factor

1992
Platelet-activating factor production during hemodialysis: effect of BN 52021.
    Prostaglandins, leukotrienes, and essential fatty acids, 1992, Volume: 45, Issue:1

    Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Amyloidosis; beta 2-Microglobulin; Biocompatible Materials; Blood Platelets; Calcimycin; Cellulose; Diterpenes; Double-Blind Method; Female; Ginkgolides; Humans; Hydroxyeicosatetraenoic Acids; Lactones; Leukopenia; Lipoxygenase; Lymphocyte Activation; Male; Membranes, Artificial; Middle Aged; Platelet Activating Factor; Platelet Activation; Random Allocation; Renal Dialysis

1992
Effects of PAF antagonist, BN52021, on the PAF-, methacholine-, and allergen-induced bronchoconstriction in asthmatic children.
    Chest, 1991, Volume: 99, Issue:4

    Topics: Allergens; Asthma; Blood Cell Count; Bronchial Provocation Tests; Bronchoconstriction; Child; Diterpenes; Double-Blind Method; Female; Ginkgolides; Humans; Lactones; Male; Methacholine Chloride; Plant Extracts; Platelet Activating Factor

1991
Effects of the platelet-activating factor receptor antagonist BN 52021 on hematologic variables and blood loss during and after cardiopulmonary bypass.
    Anesthesia and analgesia, 1994, Volume: 79, Issue:2

    Topics: Analysis of Variance; Blood Loss, Surgical; Blood Platelets; Cardiopulmonary Bypass; Diterpenes; Double-Blind Method; Female; Ginkgolides; Humans; Infusions, Intravenous; Lactones; Leukocyte Count; Leukocytes; Male; Middle Aged; Platelet Activating Factor; Platelet Count

1994
Double blind placebo controlled multicentre study of ginkgolide B in treatment of acute exacerbations of multiple sclerosis. The Ginkgolide Study Group in multiple sclerosis.
    Journal of neurology, neurosurgery, and psychiatry, 1995, Volume: 58, Issue:3

    Topics: Activities of Daily Living; Acute Disease; Adult; Diterpenes; Double-Blind Method; Female; Ginkgolides; Humans; Lactones; Male; Middle Aged; Multiple Sclerosis; Platelet Activating Factor; Recurrence; Severity of Illness Index; Treatment Outcome

1995
Platelet-activating factor receptor antagonist BN 52021 in the treatment of severe sepsis: a randomized, double-blind, placebo-controlled, multicenter clinical trial. BN 52021 Sepsis Study Group.
    Critical care medicine, 1994, Volume: 22, Issue:11

    Topics: Adult; Aged; APACHE; Diterpenes; Double-Blind Method; France; Ginkgolides; Gram-Negative Bacterial Infections; Humans; Lactones; Middle Aged; Placebos; Platelet Activating Factor; Prognosis; Statistics as Topic; Systemic Inflammatory Response Syndrome

1994
BN 52021: a platelet activating factor antagonist for preventing post-transplant renal failure. A double-blind, randomized study. The BN 52021 Study Group in Renal Transplantation.
    Annals of internal medicine, 1994, Sep-01, Volume: 121, Issue:5

    Topics: Adult; Aged; Cadaver; Diterpenes; Double-Blind Method; Female; Ginkgolides; Humans; Kidney Transplantation; Lactones; Male; Middle Aged; Pilot Projects; Platelet Activating Factor; Renal Insufficiency

1994
Effects of a paf-receptor antagonist on hemodynamics during and after cardiopulmonary bypass.
    Journal of cardiothoracic and vascular anesthesia, 1995, Volume: 9, Issue:6

    Topics: Blood Pressure; Cardiac Output; Cardiopulmonary Bypass; Coronary Artery Bypass; Diterpenes; Double-Blind Method; Female; Fibrinolytic Agents; Ginkgolides; Hemodynamics; Heparin Antagonists; Humans; Lactones; Male; Middle Aged; Placebos; Platelet Activating Factor; Platelet Membrane Glycoproteins; Prospective Studies; Protamines; Pulmonary Artery; Pulmonary Wedge Pressure; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Systole; Vascular Resistance; Ventricular Function, Left; Ventricular Function, Right

1995
Confirmatory platelet-activating factor receptor antagonist trial in patients with severe gram-negative bacterial sepsis: a phase III, randomized, double-blind, placebo-controlled, multicenter trial. BN 52021 Sepsis Investigator Group.
    Critical care medicine, 1998, Volume: 26, Issue:12

    Topics: Adult; Aged; Analysis of Variance; APACHE; Diterpenes; Double-Blind Method; Free Radical Scavengers; Ginkgolides; Gram-Negative Bacterial Infections; Humans; Lactones; Middle Aged; Platelet Activating Factor; Prospective Studies; Sepsis; Survival Analysis

1998
Impact of PAF antagonist BN 52021 (Ginkolide B) on post-ischemic graft function in clinical lung transplantation.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2001, Volume: 20, Issue:3

    Topics: Diterpenes; Double-Blind Method; Ginkgolides; Hemodynamics; Humans; Lactones; Lung Diseases; Lung Transplantation; Oxygen; Platelet Activating Factor; Prospective Studies; Reperfusion Injury

2001
LC-MS characterization of terpene lactones in plasma of experimental animals treated with Ginkgo biloba extracts Correlation with pharmacological activity.
    Journal of pharmaceutical and biomedical analysis, 2006, Feb-24, Volume: 40, Issue:3

    Topics: Adult; Animals; Biological Availability; Bronchoconstriction; Chromatography, Liquid; Diterpenes; Ginkgo biloba; Ginkgolides; Guinea Pigs; Histamine; Humans; Lactones; Male; Mass Spectrometry; Models, Molecular; Molecular Conformation; Ovalbumin; Plant Extracts; Platelet Activating Factor; Terpenes; Thromboxane B2

2006

Other Studies

446 other study(ies) available for ginkgolide b and 1-hexadecyl-2-acetyl-glycero-3-phosphocholine

ArticleYear
Endothelium-dependent effects of platelet-activating factor in the coronary circulation.
    Journal of cardiovascular pharmacology, 1992, Volume: 20 Suppl 12

    Topics: Animals; Azepines; Coronary Circulation; Coronary Vessels; Diterpenes; Dogs; Dose-Response Relationship, Drug; Endothelium, Vascular; Ginkgolides; Hemodynamics; Injections, Intra-Arterial; Injections, Intravenous; Lactones; Platelet Activating Factor; Saponins; Triazoles; Vascular Resistance; Vasoconstriction; Vasodilation

1992
Interference of BN 52021, an antagonist of PAF, with different forms of active anaphylaxis in the guinea-pig: importance of the booster injection.
    British journal of pharmacology, 1991, Volume: 102, Issue:3

    Topics: Anaphylaxis; Animals; Bronchoconstriction; Diterpenes; Female; Ginkgolides; Guinea Pigs; Histamine Release; Immunization, Secondary; In Vitro Techniques; Lactones; Lung; Male; Ovalbumin; Platelet Activating Factor; Thromboxane B2

1991
Reversal of the endotoxin-induced bronchial hyperreactivity to histamine by the platelet activating factor antagonist BN 52021.
    Pneumonologia i alergologia polska, 1992, Volume: 60 Suppl 2

    Topics: Airway Resistance; Animals; Bronchial Hyperreactivity; Bronchial Provocation Tests; Diterpenes; Endotoxins; Ginkgolides; Guinea Pigs; Histamine; Lactones; Male; Platelet Activating Factor; Premedication

1992
Inhibition of PAF-induced tPA release by KO-286011.
    Annals of the New York Academy of Sciences, 1992, Dec-04, Volume: 667

    Topics: Animals; Diterpenes; Ear; Ginkgolides; Kinetics; Lactones; Perfusion; Phospholipid Ethers; Platelet Activating Factor; Pyridinium Compounds; Swine; Tissue Plasminogen Activator

1992
Role of PAF and cytokines in microvascular tissue injury.
    The Journal of laboratory and clinical medicine, 1992, Volume: 119, Issue:5

    Topics: Cell Adhesion; Cell Movement; Cytokines; Diterpenes; Ginkgolides; Humans; In Vitro Techniques; Interleukin-1; Interleukin-2; Lactones; Microcirculation; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Shock, Septic; Tumor Necrosis Factor-alpha

1992
Formation of LTB4 by fMLP-stimulated alveolar macrophages accounts for eosinophil migration in vitro.
    Journal of leukocyte biology, 1992, Volume: 51, Issue:5

    Topics: Animals; Benzeneacetamides; Cell Movement; Chemotactic Factors, Eosinophil; Diterpenes; Eosinophils; Ginkgolides; Guinea Pigs; Hydroxamic Acids; Indomethacin; Lactones; Leukotriene B4; Lipoxygenase Inhibitors; Macrophages, Alveolar; Male; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Sensitivity and Specificity; Stimulation, Chemical

1992
Immune-complex alveolitis in the rat: evidence for platelet activating factor and leukotrienes as mediators of the vascular lesions.
    European journal of pharmacology, 1992, Mar-17, Volume: 213, Issue:1

    Topics: Alveolitis, Extrinsic Allergic; Animals; Azepines; Bronchoalveolar Lavage Fluid; Dinoprostone; Diterpenes; Econazole; Ginkgolides; Hemoglobins; Hemorrhage; Indomethacin; Lactones; Leukotriene B4; Leukotrienes; Lipoxygenase Inhibitors; Male; Platelet Activating Factor; Propionates; Quinolines; Rats; Rats, Inbred Strains; Thromboxanes; Triazoles

1992
Dexamethasone-induced gastric mucosal damage in the rat: possible role of platelet-activating factor.
    British journal of pharmacology, 1992, Volume: 105, Issue:4

    Topics: Animals; Azepines; Dexamethasone; Diterpenes; Gastric Mucosa; Ginkgolides; Lactones; Male; Platelet Activating Factor; Platelet Membrane Glycoproteins; Prostaglandins; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thienopyridines; Triazoles

1992
Reversible or irreversible modification of [3H]PAF binding on rabbit platelet membranes differentiates various PAF receptor antagonists.
    Lipids, 1992, Volume: 27, Issue:8

    Topics: Animals; Azepines; Blood Platelets; Cell Membrane; Dioxolanes; Diterpenes; Furans; Ginkgolides; Lactones; Molecular Structure; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pyridinium Compounds; Quinolinium Compounds; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Triazoles; Tritium

1992
Platelet-activating factor enhances interleukin-6 production by alveolar macrophages.
    The Journal of allergy and clinical immunology, 1992, Volume: 90, Issue:5

    Topics: Animals; Cells, Cultured; Diterpenes; Ginkgolides; Indoles; Interleukin-6; Lactones; Leukotriene B4; Macrophages, Alveolar; Male; Platelet Activating Factor; Rats; Rats, Wistar

1992
Influence of platelet activating factor antagonists on the protamine sulphate stimulated release of histamine from peritoneal mast cells of rats in vitro.
    Arzneimittel-Forschung, 1992, Volume: 42, Issue:1

    Topics: Acetophenones; Animals; Azepines; Diterpenes; Ginkgolides; Histamine Release; Humans; In Vitro Techniques; Ketotifen; Lactones; Male; Mast Cells; Peritoneal Cavity; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Protamines; Rats; Rats, Inbred Strains; Triazoles

1992
Platelet activating factor and systemic anaphylaxis in Nippostrongylus brasiliensis-sensitized rats: differential effects of PAF antagonists.
    British journal of pharmacology, 1992, Volume: 106, Issue:2

    Topics: Anaphylaxis; Animals; Azepines; Blood Proteins; Diterpenes; Evans Blue; Ginkgolides; Hemodynamics; Lactones; Male; Microspheres; Nippostrongylus; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Triazoles

1992
Separate induction of human blood platelet aggregation or cytotoxicity by different concentrations of PAF-acether and thrombin.
    Agents and actions, 1992, Volume: 36, Issue:1-2

    Topics: Animals; Cell Survival; Diterpenes; Ginkgolides; Humans; In Vitro Techniques; Lactones; Platelet Activating Factor; Platelet Aggregation; Schistosoma mansoni; Thrombin

1992
Platelet-activating factor antagonists limit glycine changes and behavioral deficits after brain trauma.
    The American journal of physiology, 1992, Volume: 263, Issue:4 Pt 2

    Topics: Animals; Azepines; Behavior, Animal; Body Water; Brain; Brain Injuries; Cations; Dialysis; Diterpenes; Ginkgolides; Glycine; Lactones; Male; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Triazoles

1992
Light and lithium effects in the rat retina: modification by the PAF antagonist BN 52021.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 1992, Volume: 230, Issue:6

    Topics: Analysis of Variance; Animals; Disease Models, Animal; Diterpenes; Ginkgolides; Image Processing, Computer-Assisted; Lactones; Light; Lithium; Male; Phagosomes; Platelet Activating Factor; Rats; Retina; Retinal Diseases; Rod Cell Outer Segment

1992
Role of platelet-activating factor in hepatic responses after bile duct ligation in rats.
    The American journal of physiology, 1992, Volume: 263, Issue:5 Pt 1

    Topics: Animals; Azepines; Bile Ducts; Cholestasis; Diterpenes; Endotoxins; Ginkgolides; Kupffer Cells; Lactones; Ligation; Lipopolysaccharides; Liver; Male; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Triazoles

1992
Aggregation of human polymorphonuclear leukocytes by endothelin: role of platelet-activating factor.
    European journal of pharmacology, 1992, Dec-02, Volume: 224, Issue:2-3

    Topics: Azepines; Calcium; Cell Aggregation; Centrifugation, Density Gradient; Cytosol; Diterpenes; Dose-Response Relationship, Drug; Endothelins; Ginkgolides; Humans; Lactones; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Triazoles

1992
Lethal and non-lethal course of endotoxic shock is determined by interactions between tumor necrosis factor, platelet activating factor and eicosanoids.
    Pathologie-biologie, 1992, Volume: 40, Issue:8

    Topics: Animals; Blood Pressure; Diterpenes; Eicosanoids; Endotoxins; Escherichia coli; Ginkgolides; Indomethacin; Lactones; Platelet Activating Factor; Shock, Septic; Swine; Thromboxane B2; Tumor Necrosis Factor-alpha

1992
Role of platelet-activating factor in the ovine heparin-protamine reaction.
    Journal of applied physiology (Bethesda, Md. : 1985), 1992, Volume: 73, Issue:6

    Topics: Animals; Blood Gas Analysis; Diterpenes; Ginkgolides; Hemodynamics; Heparin; Lactones; Platelet Activating Factor; Protamines; Pulmonary Circulation; Sheep; Whole Blood Coagulation Time

1992
The pharmacological modulation of thrombin-induced cerebral thromboembolism in the rabbit.
    British journal of pharmacology, 1992, Volume: 106, Issue:1

    Topics: Animals; Anistreplase; Arginine; Blood Platelets; Diterpenes; Female; Fibrinogen; Fibrinolytic Agents; Ginkgolides; Hirudins; Injections, Intra-Arterial; Injections, Intravenous; Intracranial Embolism and Thrombosis; Lactones; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Polydeoxyribonucleotides; Rabbits; Recombinant Proteins; Thrombin

1992
In vitro effects of PAF on venous endothelial cell actin disposition.
    Agents and actions, 1992, Volume: 35, Issue:1-2

    Topics: Actins; Animals; Calcium; Diterpenes; Endothelium, Vascular; Fluorescent Antibody Technique; Ginkgolides; Lactones; Platelet Activating Factor; Rats; Vena Cava, Inferior

1992
Platelet activating factor antagonist enhances lung preservation.
    The Journal of surgical research, 1992, Volume: 52, Issue:6

    Topics: Animals; Body Water; Diterpenes; Dogs; Ginkgolides; Lactones; Lung; Lung Compliance; Lung Transplantation; Male; Organ Preservation; Oxygen; Platelet Activating Factor; Vascular Resistance

1992
Role of platelet-activating factor in pancreatitis-associated acute lung injury in the rat.
    The American journal of pathology, 1992, Volume: 140, Issue:4

    Topics: Animals; Azepines; Bronchoalveolar Lavage Fluid; Diterpenes; Eicosanoids; Enzymes; Ginkgolides; Lactones; Lung; Pancreatitis; Platelet Activating Factor; Rats; Triazoles

1992
Histamine potentiates human platelet aggregation induced by platelet-activating factor.
    International archives of allergy and immunology, 1992, Volume: 97, Issue:1

    Topics: Diterpenes; Drug Synergism; Ethylenediamines; Ginkgolides; Histamine; Humans; Lactones; Platelet Activating Factor; Platelet Aggregation

1992
Cellular electrophysiological effects of platelet-activating factor (PAF) and its antagonist BN 52021 in cardiac preparations.
    Drugs under experimental and clinical research, 1992, Volume: 18, Issue:1

    Topics: 4-Aminopyridine; Action Potentials; Animals; Calcium; Diterpenes; Dose-Response Relationship, Drug; Ginkgolides; Guinea Pigs; Lactones; Membrane Potentials; Papillary Muscles; Platelet Activating Factor; Potassium Channels

1992
Hemodynamic effects of endotoxin and platelet activating factor in cirrhotic rats.
    Gastroenterology, 1992, Volume: 103, Issue:1

    Topics: Animals; Azepines; Blood Pressure; Diterpenes; Endotoxins; Ginkgolides; Heart Rate; Hemodynamics; Lactones; Liver Cirrhosis, Experimental; Male; Platelet Activating Factor; Portal System; Rats; Rats, Inbred Strains; Triazoles

1992
Platelet activating factor antagonist enhances lung preservation in a canine model of single lung allotransplantation.
    The Journal of thoracic and cardiovascular surgery, 1992, Volume: 104, Issue:1

    Topics: Adenosine; Allopurinol; Animals; Deferoxamine; Diterpenes; Dogs; Ginkgolides; Glutathione; Insulin; Lactones; Lung; Lung Transplantation; Male; Organ Preservation; Organ Preservation Solutions; Platelet Activating Factor; Raffinose; Reperfusion Injury; Solutions; Tissue Preservation

1992
LTB4, a potent chemotactic factor for purified guinea-pig eosinophils: interference of PAF-acether antagonists.
    International journal of immunopharmacology, 1991, Volume: 13, Issue:2-3

    Topics: Animals; Azepines; Chemotaxis, Leukocyte; Diterpenes; Eosinophils; Female; Ginkgolides; Guinea Pigs; In Vitro Techniques; Lactones; Leukotriene B4; Male; Platelet Activating Factor; Triazoles

1991
Mechanisms of the coronary vascular effects of platelet-activating factor in the rat perfused heart.
    British journal of pharmacology, 1991, Volume: 103, Issue:1

    Topics: Animals; Blood Pressure; Coronary Circulation; Diterpenes; Ginkgolides; Heart; In Vitro Techniques; Indoles; Indomethacin; Lactones; Leukotriene Antagonists; Leukotriene B4; Perfusion; Phenylbutyrates; Piperazines; Platelet Activating Factor; Rats; Rats, Inbred Strains; SRS-A

1991
Activation of guinea pig eosinophils by human recombinant IL-5. Selective priming to platelet-activating factor-acether and interference of its antagonists.
    Journal of immunology (Baltimore, Md. : 1950), 1991, Oct-15, Volume: 147, Issue:8

    Topics: Animals; Calcium; Cell Movement; Diterpenes; Eosinophils; Ginkgolides; Guinea Pigs; Humans; Interleukin-5; Lactones; Leukotriene B4; Lipopolysaccharides; Platelet Activating Factor; Recombinant Proteins; Superoxides

1991
Prehispanolone, a novel platelet activating factor receptor antagonist from Leonurus heterophyllus.
    British journal of pharmacology, 1991, Volume: 103, Issue:3

    Topics: Adenosine Diphosphate; Animals; Cell Membrane; Diterpenes; Drugs, Chinese Herbal; Ginkgolides; In Vitro Techniques; Lactones; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Protein Binding; Rabbits; Radioligand Assay; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Serum Albumin, Bovine; Sodium; Structure-Activity Relationship; Thrombin

1991
Species-dependent differences of high affinity [3H]PAF-binding to platelets from humans and pigs and its inhibition by selected antagonists.
    Journal of lipid mediators, 1991, Volume: 4, Issue:3

    Topics: Animals; Azepines; Blood Platelets; Diterpenes; Ginkgolides; Humans; Lactones; Platelet Activating Factor; Platelet Aggregation; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Species Specificity; Swine; Triazoles

1991
Effects of endothelin-1 on vascular permeability in the conscious rat: interactions with platelet-activating factor.
    British journal of pharmacology, 1991, Volume: 104, Issue:4

    Topics: Animals; Azepines; Blood Pressure; Capillary Permeability; Diterpenes; Endothelins; Ginkgolides; Hematocrit; In Vitro Techniques; Lactones; Male; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Triazoles

1991
Platelet activating factor antagonists interact with GABAA receptors.
    Research communications in chemical pathology and pharmacology, 1991, Volume: 74, Issue:2

    Topics: Animals; Benzodiazepines; Binding Sites; Chlorides; Dioxolanes; Diterpenes; Ginkgolides; Lactones; Male; Mice; Platelet Activating Factor; Quinolinium Compounds; Receptors, GABA-A

1991
Effect of platelet-activating factor on tumor necrosis factor-induced superoxide generation from human neutrophils. Possible involvement of G proteins.
    Lipids, 1991, Volume: 26, Issue:12

    Topics: Cholera Toxin; Dioxolanes; Diterpenes; Drug Interactions; Ginkgolides; GTP-Binding Proteins; Humans; In Vitro Techniques; Kinetics; Lactones; Neutrophils; Platelet Activating Factor; Pyridinium Compounds; Superoxides; Tumor Necrosis Factor-alpha; Virulence Factors, Bordetella

1991
Role of free radicals and platelet-activating factor in the genesis of intestinal motor disturbances induced by Escherichia coli endotoxins in rats.
    Gastroenterology, 1991, Volume: 100, Issue:4

    Topics: Animals; Diarrhea; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Diterpenes; Electromyography; Endotoxins; Escherichia coli; Free Radical Scavengers; Free Radicals; Gastrointestinal Motility; Ginkgolides; Indomethacin; Intestine, Small; Lactones; Male; Muscle, Smooth; Platelet Activating Factor; Rats; Rats, Inbred Strains

1991
Ro 19-3704 directly inhibits immunoglobulin E-dependent mediator release by a mechanism independent of its platelet-activating factor antagonist properties.
    European journal of pharmacology, 1990, Feb-13, Volume: 176, Issue:3

    Topics: Animals; Azepines; Diterpenes; Ginkgolides; Glyceryl Ethers; Histamine Release; Humans; Immunoglobulin E; Inositol Phosphates; L-Lactate Dehydrogenase; Lactones; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Rats; Substance P; Synovial Fluid; Thiazoles; Triazines; Triazoles; Tumor Cells, Cultured

1990
Bleomycin-induced lung injury in the rat: effects of the platelet-activating factor (PAF) receptor antagonist BN 52021 and platelet depletion.
    Environmental health perspectives, 1990, Volume: 85

    Topics: Administration, Inhalation; Administration, Oral; Albumins; Animals; Bleomycin; Diterpenes; Dose-Response Relationship, Drug; Extracellular Space; Ginkgolides; Lactones; Lung Diseases; Male; Organ Size; Platelet Activating Factor; Platelet Count; Rats; Rats, Inbred Lew

1990
Immune release of histamine and other lipid mediators from guinea-pig isolated kidney: antagonism by BN-52021.
    Agents and actions, 1990, Volume: 30, Issue:3-4

    Topics: Animals; Biological Assay; Diterpenes; Ginkgolides; Guinea Pigs; Histamine Release; In Vitro Techniques; Kidney; Lactones; Male; Ovalbumin; Platelet Activating Factor; Radioimmunoassay; SRS-A; Thromboxane B2

1990
Evidence for platelet-activating factor as a late-phase mediator of chronic pancreatitis in the rat.
    The American journal of pathology, 1990, Volume: 137, Issue:6

    Topics: Amylases; Animals; Azepines; Chronic Disease; Diterpenes; Ginkgolides; Lactones; Ligation; Male; Pancreas; Pancreatic Ducts; Pancreatitis; Platelet Activating Factor; Rats; Rats, Inbred Strains; Time Factors; Triazoles

1990
Role of platelet-activating factor in hemodynamic derangements in an acute rodent pancreatic model.
    Gastroenterology, 1992, Volume: 102, Issue:1

    Topics: Acute Disease; Animals; Diterpenes; Ginkgolides; Hemodynamics; Lactones; Male; Pancreatitis; Platelet Activating Factor; Rats; Rats, Inbred Strains; Splanchnic Circulation

1992
Interactions between platelet-activating factor and prostanoids during mesenteric ischemia-reperfusion-induced shock in the anesthetized dog.
    Circulatory shock, 1991, Volume: 35, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Dinoprost; Diterpenes; Dogs; Ginkgolides; Hemodynamics; Indomethacin; Lactones; Male; Mesenteric Arteries; Mesenteric Veins; Platelet Activating Factor; Prostaglandins; Reperfusion Injury; Shock; Thromboxane B2

1991
Role of platelet activating factor in gentamicin and cisplatin nephrotoxicity.
    Kidney international, 1991, Volume: 40, Issue:4

    Topics: Acute Kidney Injury; Animals; Cisplatin; Diterpenes; Gentamicins; Ginkgolides; Glomerular Filtration Rate; Kidney; Lactones; Plant Extracts; Platelet Activating Factor; Rats; Rats, Inbred Strains

1991
PAF induces rat plasma extravasation and releases eicosanoids during anaphylaxis.
    Inflammation, 1991, Volume: 15, Issue:5

    Topics: Anaphylaxis; Animals; Blood Proteins; Capillary Permeability; Diterpenes; Eicosanoids; Ginkgolides; Indomethacin; Lactones; Male; Methysergide; Peritoneal Cavity; Platelet Activating Factor; Pyrilamine; Rats; Rats, Inbred Strains

1991
Cell adhesion by membrane-bound paf-acether.
    International immunology, 1991, Volume: 3, Issue:11

    Topics: Animals; Azepines; Calcimycin; Cell Adhesion; Diterpenes; Ginkgolides; Humans; In Vitro Techniques; Lactones; Neutrophils; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Triazoles; Zymosan

1991
Platelet activating factor is one of the mediators involved in endotoxic shock in pigs.
    Journal of lipid mediators, 1991, Volume: 4, Issue:3

    Topics: Animals; Diterpenes; Escherichia coli; Female; Ginkgolides; Hemodynamics; Hemoglobins; Lactones; Leukocyte Count; Lipopolysaccharides; Platelet Activating Factor; Platelet Count; Regional Blood Flow; Shock, Septic; Swine; Tumor Necrosis Factor-alpha

1991
Effect of platelet-activating factor on porcine pulmonary blood vessels in vitro.
    Naunyn-Schmiedeberg's archives of pharmacology, 1991, Volume: 344, Issue:4

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Azepines; Calcimycin; Diterpenes; Eicosanoids; Ginkgolides; In Vitro Techniques; Lactones; Male; Muscle Contraction; Muscle, Smooth, Vascular; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pulmonary Circulation; Radioimmunoassay; SRS-A; Swine; Thromboxane B2; Triazoles

1991
Effects of ginkgolide B, a platelet-activating factor inhibitor on insulitis in the spontaneously diabetic BB rat.
    Autoimmunity, 1991, Volume: 9, Issue:3

    Topics: Animals; Diabetes Mellitus, Type 1; Disease Models, Animal; Diterpenes; Dose-Response Relationship, Drug; Eosinophils; Female; Ginkgolides; Immunohistochemistry; Islets of Langerhans; Lactones; Male; Pancreatitis; Platelet Activating Factor; Rats; Rats, Inbred BB

1991
Mechanisms of thrombocytopenia in the acute phase of antigen-induced arthritis in rabbits.
    Prostaglandins, 1991, Volume: 42, Issue:6

    Topics: Animals; Arthritis, Experimental; Diterpenes; Econazole; Female; Ginkgolides; Indoles; Indomethacin; Lactones; Male; Platelet Activating Factor; Rabbits; Synovial Fluid; Thrombocytopenia; Thromboxane A2; Thromboxane B2

1991
Effect of long-term infusion of platelet-activating factor on pulmonary responsiveness and morphology in the guinea-pig.
    Pulmonary pharmacology, 1991, Volume: 4, Issue:1

    Topics: Animals; Blood Cell Count; Bronchi; Diterpenes; Dose-Response Relationship, Drug; Drug Hypersensitivity; Ginkgolides; Guinea Pigs; Histamine; Lactones; Lung; Male; Platelet Activating Factor; Serum Albumin, Bovine; Time Factors

1991
[Experimental and clinical study of activated platelet in allergic asthma].
    Zhonghua nei ke za zhi, 1991, Volume: 30, Issue:9

    Topics: 6-Ketoprostaglandin F1 alpha; Adolescent; Adult; Animals; Asthma; Diterpenes; Female; Ginkgolides; Guinea Pigs; Humans; Lactones; Male; Middle Aged; Platelet Activating Factor; Platelet Aggregation; Platelet Factor 4

1991
Influence of aminophylline and ketotifen in comparison to the lipoxygenase inhibitors NDGA and esculetin and the PAF antagonists WEB 2170 [correction of 2107] and BN 52021 on endothelin-1 induced vaso- and bronchoconstriction.
    Prostaglandins, leukotrienes, and essential fatty acids, 1991, Volume: 44, Issue:3

    Topics: Aminophylline; Animals; Azepines; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Bronchoconstrictor Agents; Diterpenes; Endothelins; Ginkgolides; Guinea Pigs; Ketotifen; Lactones; Lipoxygenase Inhibitors; Lung; Male; Masoprocol; Platelet Activating Factor; Platelet Aggregation Inhibitors; Theophylline; Thromboxane B2; Triazoles; Umbelliferones; Vasoconstriction; Vasoconstrictor Agents

1991
Effects of PAF antagonists on renal vascular escape and tachyphylaxis in perfused rabbit kidney.
    Lipids, 1991, Volume: 26, Issue:12

    Topics: Animals; Azepines; Diterpenes; Female; Gangliosides; Ginkgolides; In Vitro Techniques; Kidney; Kinetics; Lactones; Male; Perfusion; Platelet Activating Factor; Pyridines; Rabbits; Renal Circulation; Tachyphylaxis; Thiazoles; Time Factors; Triazoles

1991
Platelet-activating factor may mediate dexamethasone-induced gastric damage in the rat.
    Lipids, 1991, Volume: 26, Issue:12

    Topics: Animals; Chromatography, Thin Layer; Dexamethasone; Diterpenes; Gastric Mucosa; Ginkgolides; Lactones; Male; Platelet Activating Factor; Rats; Rats, Inbred Strains; Stomach

1991
Myoelectric intestinal disturbances in Escherichia coli endotoxic shock in rats. Involvement of platelet-activating factor.
    Lipids, 1991, Volume: 26, Issue:12

    Topics: Animals; Diterpenes; Duodenum; Endotoxins; Escherichia coli; Ginkgolides; Indomethacin; Jejunum; Lactones; Male; Muscle, Smooth; Platelet Activating Factor; Rats; Rats, Inbred Strains; Shock, Septic

1991
Pooling of blood in postischemic shock is modulated by platelet-activating factor (PAF).
    Lipids, 1991, Volume: 26, Issue:12

    Topics: Animals; Blood Pressure; Coronary Circulation; Diterpenes; Dogs; Ginkgolides; Hemodynamics; Hindlimb; Ischemia; Lactones; Platelet Activating Factor; Reperfusion; Shock

1991
Leukotrienes in cerebrospinal fluid of the conscious cat: effect of platelet-activating factor and pyrogens.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1991, Volume: 21A

    Topics: Animals; Cats; Diterpenes; Endotoxins; Fever; Ginkgolides; Indomethacin; Interleukin-1; Lactones; Leukotrienes; Lipoxygenase Inhibitors; Platelet Activating Factor; Recombinant Proteins; Stimulation, Chemical

1991
Platelet-activating factor stimulates the release of atrial natriuretic factor from the rat heart.
    The Journal of endocrinology, 1991, Volume: 130, Issue:2

    Topics: Animals; Atrial Natriuretic Factor; Chromatography, High Pressure Liquid; Diterpenes; Ginkgolides; Heart; Lactones; Male; Myocardium; Perfusion; Platelet Activating Factor; Radioimmunoassay; Rats; Rats, Inbred Strains; Stimulation, Chemical

1991
PAF-like activity of O-acetylated sphingomyelin.
    Biomedical science, 1991, Volume: 2, Issue:5

    Topics: Acetylation; Animals; Diterpenes; Ginkgolides; Lactones; Platelet Activating Factor; Platelet Aggregation; Rabbits; Sphingomyelins; Starfish; Swine

1991
Enterolobin induces rat paw oedema independently of PAF-acether.
    Memorias do Instituto Oswaldo Cruz, 1991, Volume: 86 Suppl 2

    Topics: Animals; Azepines; Dihydropyridines; Diterpenes; Edema; Ginkgolides; Lactones; Male; Plant Proteins; Platelet Activating Factor; Rats; Rats, Wistar; Triazoles

1991
Granulocyte-macrophage colony-stimulating factor increases the synthesis of leukotriene B4 by human neutrophils in response to platelet-activating factor. Enhancement of both arachidonic acid availability and 5-lipoxygenase activation.
    Journal of immunology (Baltimore, Md. : 1950), 1991, Feb-15, Volume: 146, Issue:4

    Topics: Arachidonate 5-Lipoxygenase; Arachidonic Acid; Arachidonic Acids; Chromatography, High Pressure Liquid; Diterpenes; Enzyme Activation; Ginkgolides; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Lactones; Leukotriene B4; Neutrophils; Platelet Activating Factor

1991
Platelet-activating factor affects cytosolic free calcium concentration and prolactin secretion in GH4C1 rat pituitary cells.
    Biochemical and biophysical research communications, 1991, Jan-31, Volume: 174, Issue:2

    Topics: Animals; Calcium; Calcium Channels; Cell Line; Diterpenes; Dose-Response Relationship, Drug; Egtazic Acid; Ginkgolides; Kinetics; Lactones; Pituitary Neoplasms; Platelet Activating Factor; Potassium Chloride; Prolactin; Rats; Thyrotropin-Releasing Hormone; Verapamil

1991
Hypotensive action of IgG preparations containing aggregates is suppressed by PAF-receptor antagonist BN 52021 and by gadolinium chloride (an agent blocking Kupffer cell function).
    Agents and actions, 1991, Volume: 32, Issue:3-4

    Topics: Animals; Captopril; Diterpenes; Female; Gadolinium; Ginkgolides; Hypotension; Immunoglobulin G; Kupffer Cells; Lactones; Macromolecular Substances; Platelet Activating Factor; Rats; Rats, Inbred Strains

1991
Contribution of platelets and platelet-activating factor (PAF) to the arrhythmogenic, haemodynamic and necrotic effects of acute myocardial ischaemia.
    European heart journal, 1991, Volume: 12, Issue:5

    Topics: Animals; Arrhythmias, Cardiac; Blood Platelets; Diterpenes; Ginkgolides; Hypotension; Imidazoles; Immune Sera; Lactones; Myocardial Infarction; Necrosis; Platelet Activating Factor; Platelet Activation; Pyridines; Rabbits; Thromboxane A2; Thromboxane-A Synthase

1991
Platelet-leukocyte interaction in adhesion to endothelial cells induced by platelet-activating factor in vitro.
    British journal of pharmacology, 1991, Volume: 103, Issue:2

    Topics: Adenine; Animals; Azepines; Blood Platelets; Cell Adhesion; Diterpenes; Endothelium, Vascular; Female; Ginkgolides; Humans; In Vitro Techniques; Lactones; Leukocytes; Neutrophils; Platelet Activating Factor; Platelet Adhesiveness; Pregnancy; Rabbits; Thiazoles; Triazoles; Umbilical Veins

1991
Rapid and selective measurement of platelet-activating factor using a quantitative bioassay of platelet aggregation.
    Journal of pharmacological methods, 1991, Volume: 26, Issue:1

    Topics: Animals; Aspirin; Biological Assay; Diterpenes; Dose-Response Relationship, Drug; Ginkgolides; In Vitro Techniques; Kinetics; Lactones; Male; Phosphoenolpyruvate; Platelet Activating Factor; Platelet Aggregation; Platelet Count; Pyruvate Kinase; Rabbits

1991
Bradykinin induces eosinophil accumulation in the rat pleural cavity.
    International archives of allergy and applied immunology, 1991, Volume: 95, Issue:2-3

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Benzeneacetamides; Bradykinin; Cell Movement; Chemotaxis; Diterpenes; Dose-Response Relationship, Drug; Eosinophilia; Female; Ginkgolides; Hydroxamic Acids; Injections, Intraperitoneal; Lactones; Lipoxygenase Inhibitors; Male; Neutrophils; Platelet Activating Factor; Pleura; Pleurisy; Rats; Rats, Inbred Strains

1991
Effects of the platelet-activating factor antagonist BN 52021 on anti-islet cytotoxicity of mononuclear cells and serum from type 1 (insulin-dependent) diabetic patients.
    International archives of allergy and applied immunology, 1991, Volume: 95, Issue:4

    Topics: Adolescent; Adult; Cytotoxicity Tests, Immunologic; Cytotoxicity, Immunologic; Diabetes Mellitus, Type 1; Diterpenes; Dose-Response Relationship, Drug; Female; Ginkgolides; Humans; In Vitro Techniques; Islets of Langerhans; Lactones; Leukocytes, Mononuclear; Male; Platelet Activating Factor

1991
Tumor necrosis factor alpha 'primes' the platelet-activating factor-induced superoxide production by human neutrophils: possible involvement of G proteins.
    Journal of lipid mediators, 1990, Volume: 2 Suppl

    Topics: Cholera Toxin; Diterpenes; Drug Interactions; Ginkgolides; GTP-Binding Proteins; Humans; In Vitro Techniques; Lactones; Neutrophils; Pertussis Toxin; Platelet Activating Factor; Superoxides; Tumor Necrosis Factor-alpha; Virulence Factors, Bordetella

1990
Cooperation between tumor necrosis factor (TNF) and platelet-activating factor (PAF) in the inflammatory response.
    Journal of lipid mediators, 1990, Volume: 2 Suppl

    Topics: Animals; Arthritis; Diterpenes; Drug Synergism; Ginkgolides; Humans; In Vitro Techniques; Inflammation; Lactones; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Superoxides; Tumor Necrosis Factor-alpha

1990
Pharmacological modulation of 2-methyl-carbamate-PAF induced rat paw oedema.
    The Journal of pharmacy and pharmacology, 1990, Volume: 42, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbamates; Diterpenes; Edema; Female; Ginkgolides; Lactones; Male; Platelet Activating Factor; Rats; Rats, Inbred Strains

1990
PAF-acether in AK-5 tumour cells.
    Cell biology international reports, 1991, Volume: 15, Issue:1

    Topics: Animals; Diterpenes; Fibroma; Ginkgolides; Humans; Lactones; Phospholipases; Platelet Activating Factor; Platelet Aggregation; Tumor Cells, Cultured

1991
The effect of platelet activating factor antagonist (BN 52021) on cerulein-induced acute pancreatitis with reference to oxygen radicals.
    International journal of pancreatology : official journal of the International Association of Pancreatology, 1991, Volume: 8, Issue:1

    Topics: alpha-Amylases; Animals; Ceruletide; Diterpenes; Edema; Free Radicals; Ginkgolides; Lactones; Lipid Peroxidation; Male; Oxygen; Pancreatitis; Platelet Activating Factor; Rats; Rats, Inbred Strains; Superoxide Dismutase

1991
Generation of an eosinophilotactic activity in the pleural cavity of platelet-activating factor-injected rats.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 257, Issue:3

    Topics: Animals; Chemotactic Factors, Eosinophil; Chemotaxis, Leukocyte; Cycloheximide; Dactinomycin; Dexamethasone; Diterpenes; Drug Stability; Eosinophils; Ginkgolides; Lactones; Male; Platelet Activating Factor; Pleura; Rats; Rats, Inbred Strains; Temperature

1991
Long-term lung preservation with the PAF antagonist BN 52021.
    Transplantation, 1991, Volume: 51, Issue:6

    Topics: Animals; Diterpenes; Dogs; Ginkgolides; Lactones; Lung Transplantation; Organ Preservation; Oxygen; Platelet Activating Factor; Respiratory Function Tests; Time Factors

1991
Characterization of platelet-activating factor-induced elevation of cytosolic free-calcium level in neurohybrid NCB-20 cells.
    Neuroscience, 1991, Volume: 41, Issue:1

    Topics: Animals; Azepines; Calcium; Calcium Channel Blockers; Cerebral Cortex; Cricetinae; Cricetulus; Cytosol; Diterpenes; Gallic Acid; Ginkgolides; Hybrid Cells; Lactones; Mice; Neuroblastoma; Platelet Activating Factor; Quinolinium Compounds; Triazoles

1991
Free radicals scavengers attenuate platelet-activating factor (PAF)- and endotoxin-induced intestinal myoelectric disturbances in rats.
    Free radical research communications, 1991, Volume: 12-13 Pt 2

    Topics: Animals; Diterpenes; Endotoxins; Free Radical Scavengers; Ginkgolides; Intestines; Lactones; Male; Myoelectric Complex, Migrating; Platelet Activating Factor; Rats; Rats, Inbred Strains

1991
Superoxide dismutase (SOD) and the PAF-antagonist (BN 52021) reduce small intestinal damage induced by ischemia-reperfusion.
    Free radical research communications, 1991, Volume: 12-13 Pt 2

    Topics: Animals; Diterpenes; Female; Ginkgolides; Intestinal Mucosa; Intestine, Small; Lactones; Microscopy, Electron, Scanning; Platelet Activating Factor; Rats; Rats, Inbred Strains; Reperfusion Injury; Superoxide Dismutase

1991
Role of eicosanoids in PAF-induced increases of the vascular permeability in rat airways.
    British journal of pharmacology, 1990, Volume: 101, Issue:4

    Topics: Animals; Capillary Permeability; Diterpenes; Eicosanoids; Evans Blue; Ginkgolides; Lactones; Male; Norepinephrine; Platelet Activating Factor; Prostaglandin Endoperoxides, Synthetic; Rats; Rats, Inbred Strains; Respiratory System; SRS-A; Thromboxanes

1990
Platelet-activating factor (PAF) inhibitory profile of KO-286011 on blood platelets in vitro and in vivo.
    Naunyn-Schmiedeberg's archives of pharmacology, 1990, Volume: 342, Issue:6

    Topics: Animals; Blood Platelets; Diterpenes; Dose-Response Relationship, Drug; Ginkgolides; Guinea Pigs; Humans; Injections, Intravenous; Lactones; Male; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyridinium Compounds; Rabbits; Serotonin; Thromboxane B2

1990
Platelet activating factor antagonists do not alter normal cerebral blood flow or cerebral oxygen consumption.
    Advances in experimental medicine and biology, 1990, Volume: 277

    Topics: Animals; Azepines; Brain; Cerebrovascular Circulation; Diterpenes; Ginkgolides; Indomethacin; Lactones; Male; Oxygen Consumption; Platelet Activating Factor; Rats; Rats, Inbred Strains; Triazoles

1990
Relationships between tumour necrosis factor, eicosanoids and platelet-activating factor as mediators of endotoxin-induced shock in mice.
    British journal of pharmacology, 1990, Volume: 99, Issue:3

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Capillary Permeability; Diterpenes; Drug Interactions; Eicosanoids; Endotoxins; Escherichia coli; Female; Ginkgolides; Hematocrit; Indomethacin; Lactones; Mice; Platelet Activating Factor; Recombinant Proteins; Shock, Septic; Tumor Necrosis Factor-alpha

1990
Balanced antiinflammation: the combined application of a PAF inhibitor and a cyclooxygenase inhibitor blocks the inflammatory take-off after burns.
    International journal of tissue reactions, 1990, Volume: 12, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Burns; Cyclooxygenase Inhibitors; Diterpenes; Drug Combinations; Ginkgolides; Lactones; Platelet Activating Factor; Swine; Wound Healing

1990
The synergism between platelet-activating factor and interleukin-1 on cartilage breakdown.
    Journal of lipid mediators, 1990, Volume: 2 Suppl

    Topics: Animals; Arthritis; Cartilage, Articular; Diterpenes; Drug Synergism; Ginkgolides; Glycosaminoglycans; In Vitro Techniques; Interleukin-1; Lactones; Male; Platelet Activating Factor; Proteoglycans; Rats; Rats, Inbred Strains

1990
Effect of the PAF antagonist BN 52021 in ovine endotoxin shock.
    Journal of lipid mediators, 1990, Volume: 2 Suppl

    Topics: Animals; Diterpenes; Ginkgolides; Lactones; Lipopolysaccharides; Lung; Lymph; Platelet Activating Factor; Pulmonary Circulation; Sheep; Shock, Septic; Water-Electrolyte Balance

1990
Platelet-activating factor potentiates interleukin-1/epidermal cell-derived thymocyte-activating factor release by guinea-pig keratinocytes stimulated with lipopolysaccharide.
    Journal of lipid mediators, 1990, Volume: 2 Suppl

    Topics: Animals; Azepines; Diterpenes; Drug Synergism; Ginkgolides; Guinea Pigs; In Vitro Techniques; Interleukin-1; Keratinocytes; Lactones; Lipopolysaccharides; Platelet Activating Factor; Thienopyridines

1990
Effects of platelet activating factor antagonists on arachidonic acid-induced platelet aggregation and TXA2 formation.
    Prostaglandins, leukotrienes, and essential fatty acids, 1990, Volume: 41, Issue:3

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Azepines; Blood Platelets; Diterpenes; Ginkgolides; Imidazoles; In Vitro Techniques; Lactones; Naphthalenes; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Receptors, Prostaglandin; Receptors, Thromboxane; Sulfonamides; Thromboxane A2; Thromboxane-A Synthase; Triazoles

1990
Effect of platelet-activating factor on hypothalamic and hypophyseal pro-opiomelanocortin-related peptides and hypothalamo-pituitary-adrenal axis in the rat.
    European journal of pharmacology, 1990, Feb-27, Volume: 177, Issue:3

    Topics: Adrenocorticotropic Hormone; alpha-MSH; Animals; beta-Endorphin; Diterpenes; Ginkgolides; Hypothalamo-Hypophyseal System; Hypothalamus; In Vitro Techniques; Lactones; Male; Peptides; Pituitary Gland, Posterior; Pituitary-Adrenal System; Platelet Activating Factor; Pro-Opiomelanocortin; Radioimmunoassay; Rats; Rats, Inbred Strains

1990
Cytotoxic enzyme release and oxygen centered radical formation in human neutrophils are selectively inhibited by E-type prostaglandins but not by PGI2.
    Naunyn-Schmiedeberg's archives of pharmacology, 1990, Volume: 341, Issue:4

    Topics: Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium; Cyclic AMP; Diterpenes; Epoprostenol; Free Radicals; Ginkgolides; Glucuronidase; Humans; In Vitro Techniques; Lactones; Lysosomes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Prostaglandins E; Superoxides

1990
Distinct platelet-activating factor binding sites in synaptic endings and in intracellular membranes of rat cerebral cortex.
    The Journal of biological chemistry, 1990, Jun-05, Volume: 265, Issue:16

    Topics: Animals; Binding, Competitive; Cell Fractionation; Centrifugation, Density Gradient; Cerebral Cortex; Diterpenes; Ginkgolides; Intracellular Membranes; Lactones; Male; Microsomes; Mitochondria; Phospholipid Ethers; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Synapses; Synaptic Membranes

1990
Role of platelet-activating factor in ischemia/reperfusion-induced leukocyte adherence.
    The American journal of physiology, 1990, Volume: 259, Issue:2 Pt 1

    Topics: Animals; Azepines; Cats; Cell Adhesion; Diterpenes; Ginkgolides; Intestine, Small; Ischemia; Lactones; Leukocytes; Mesenteric Arteries; Muscle, Smooth, Vascular; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Reference Values; Reperfusion; Triazoles

1990
Ginkgolides and platelet-activating factor binding sites.
    Methods in enzymology, 1990, Volume: 187

    Topics: Animals; Blood Platelets; Brain; Cell Membrane; Ciliary Body; Diterpenes; Gerbillinae; Ginkgolides; Iris; Kinetics; Lactones; Male; Molecular Structure; Plant Extracts; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rabbits; Radioligand Assay; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Structure-Activity Relationship; Tritium

1990
Platelet-activating factor mediates glycerol-induced acute renal failure in rats.
    Clinical science (London, England : 1979), 1990, Volume: 79, Issue:6

    Topics: Acute Kidney Injury; Alprazolam; Animals; Disease Models, Animal; Diterpenes; Ginkgolides; Glomerular Filtration Rate; Glycerol; Kidney; Kidney Failure, Chronic; Lactones; Male; Plant Extracts; Platelet Activating Factor; Rats; Rats, Inbred Strains

1990
Platelet activating factor receptor antagonist improves survival and attenuates eicosanoid release in severe endotoxemia.
    Annals of surgery, 1990, Volume: 211, Issue:3

    Topics: Animals; Dinoprostone; Diterpenes; Endotoxins; Escherichia coli; Ginkgolides; Lactones; Male; Plant Extracts; Platelet Activating Factor; Rats; Rats, Inbred Strains; Shock, Septic; Thromboxane B2

1990
Capillary leakage complicated by compartment syndrome necessitating surgery.
    Intensive care medicine, 1990, Volume: 16, Issue:5

    Topics: Adult; Capillary Permeability; Compartment Syndromes; Diterpenes; Fluid Therapy; Ginkgolides; HIV Infections; Humans; Lactones; Male; Platelet Activating Factor; Rhabdomyolysis; Shock

1990
Inflammatory mediators are involved in the Candida albicans killing activity of human epidermal cells.
    Archives of dermatological research, 1990, Volume: 282, Issue:5

    Topics: Candida albicans; Dexamethasone; Dinoprostone; Diterpenes; Epidermal Cells; Epidermis; Ginkgolides; Humans; Indomethacin; Inflammation; Interleukin-1; Lactones; Phagocytosis; Platelet Activating Factor; Recombinant Proteins; Ultraviolet Rays

1990
Effect of the platelet-activating factor (PAF) antagonist, BN 52021, on free radical-induced intestinal ischemia-reperfusion damage in the rat.
    Advances in experimental medicine and biology, 1990, Volume: 264

    Topics: Allopurinol; Animals; Dimethyl Sulfoxide; Diterpenes; Female; Free Radicals; Ginkgolides; Intestinal Diseases; Intestinal Mucosa; Ischemia; Lactones; Platelet Activating Factor; Rats; Rats, Inbred Strains; Reperfusion Injury; Superoxide Dismutase

1990
Alterations in regional blood flow in rats following sensitization to the nematode Nippostrongylus brasiliensis: effects of PAF antagonists.
    British journal of pharmacology, 1990, Volume: 101, Issue:1

    Topics: Animals; Anthelmintics; Azepines; Blood Pressure; Cardiac Output; Diterpenes; Ginkgolides; Heart Rate; Immunization; Injections, Intraperitoneal; Lactones; Liver Circulation; Male; Microspheres; Nippostrongylus; Platelet Activating Factor; Rats; Rats, Inbred Strains; Regional Blood Flow; Submandibular Gland; Triazoles; Vascular Resistance

1990
Platelet-activating factor antagonist, BN-52021 protects against cis-diamminedichloroplatinum nephrotoxicity in the rat.
    Renal failure, 1990, Volume: 12, Issue:3

    Topics: Acute Kidney Injury; Animals; Blood Urea Nitrogen; Body Weight; Cisplatin; Creatinine; Diterpenes; Ginkgolides; Glomerular Filtration Rate; Lactones; Male; Platelet Activating Factor; Rats; Rats, Inbred Strains; Renal Circulation; Tumor Cells, Cultured

1990
Endothelin-induced constriction of guinea pig airways: role of platelet-activating factor.
    European journal of pharmacology, 1990, Sep-21, Volume: 186, Issue:2-3

    Topics: Animals; Bronchoconstriction; Diterpenes; Endothelins; Ginkgolides; Guinea Pigs; Histamine; In Vitro Techniques; Lactones; Male; Muscle, Smooth; Platelet Activating Factor; Trachea

1990
PAF antagonist ginkgolide B reduces postischemic neuronal damage in rat brain hippocampus.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1990, Volume: 10, Issue:1

    Topics: Animals; Brain Ischemia; Cell Survival; Diterpenes; Ginkgolides; Hippocampus; Lactones; Male; Necrosis; Neurons; Plant Extracts; Platelet Activating Factor; Rats; Rats, Inbred Strains

1990
Inhibition of Ehrlich ascites tumor in vivo by PAF-antagonists.
    International journal of immunopharmacology, 1990, Volume: 12, Issue:1

    Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cell Adhesion; Cell Division; Diterpenes; Ginkgolides; Hydrogen Peroxide; Lactones; Macrophages; Male; Mice; Platelet Activating Factor; Quinolinium Compounds

1990
Endogenous platelet activating factor does not modulate blood flow and metabolism in normal rat brain.
    Stroke, 1990, Volume: 21, Issue:3

    Topics: Animals; Azepines; Blood Pressure; Brain; Cerebrovascular Circulation; Diterpenes; Ginkgolides; Indomethacin; Lactones; Male; Oxygen; Platelet Activating Factor; Rats; Rats, Inbred Strains; Reference Values; Triazines; Triazoles

1990
Failure of platelet-activating factor (PAF-acether) to induce decidualization in mice and failure of antagonists of PAF to inhibit implantation.
    Journal of reproduction and fertility, 1990, Volume: 88, Issue:1

    Topics: Animals; Azepines; Decidua; Diterpenes; Embryo Implantation; Estradiol; Female; Ginkgolides; Lactones; Mice; Mice, Inbred Strains; Ovariectomy; Phospholipid Ethers; Platelet Activating Factor; Pregnancy; Progesterone; Triazines; Triazoles

1990
Platelet-activating factor antagonists treatment protects against postischemic acute renal failure in rats.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 253, Issue:1

    Topics: Acute Kidney Injury; Alprazolam; Animals; Diterpenes; Ginkgolides; Glomerular Filtration Rate; Ischemia; Kidney; Lactones; Male; Platelet Activating Factor; Rats; Rats, Inbred Strains

1990
Effect of BN 52021, a platelet activating factor antagonist, on dithranol-induced inflammation.
    The British journal of dermatology, 1990, Volume: 122, Issue:4

    Topics: Adult; Anthralin; Capillary Resistance; Dermatitis, Contact; Diterpenes; Female; Ginkgolides; Humans; Lactones; Male; Middle Aged; Platelet Activating Factor; Skin; Skin Temperature; Skinfold Thickness

1990
Platelet-activating factor mediates gastric damage induced by hemorrhagic shock.
    The American journal of physiology, 1990, Volume: 259, Issue:1 Pt 1

    Topics: Animals; Azepines; Diterpenes; Gastric Mucosa; Ginkgolides; Lactones; Male; Membrane Potentials; Muscle, Smooth; Platelet Activating Factor; Rats; Rats, Inbred Strains; Regional Blood Flow; Shock, Hemorrhagic; Stomach; Triazoles

1990
Effect of long-term treatment with platelet-activating factor on IL-1 and IL-2 production by rat spleen cells.
    Journal of immunology (Baltimore, Md. : 1950), 1990, Aug-01, Volume: 145, Issue:3

    Topics: Animals; Diterpenes; Ginkgolides; Interleukin-1; Interleukin-2; Lactones; Lipopolysaccharides; Platelet Activating Factor; Rats; Rats, Inbred Strains; Spleen

1990
Effects of platelet activating factor on contractile force and 45Ca fluxes in guinea-pig isolated atria.
    British journal of pharmacology, 1990, Volume: 100, Issue:2

    Topics: Action Potentials; Animals; Calcium; Calcium Radioisotopes; Cell Membrane; Diterpenes; Female; Ginkgolides; Guinea Pigs; Heart; In Vitro Techniques; Lactones; Male; Microelectrodes; Muscle Contraction; Myocardial Contraction; Myocardium; Platelet Activating Factor; Sodium; Verapamil

1990
Evidence for a role of platelet activating factor in the pathogenesis of irreversible but not reversible myocardial injury after reperfusion in dogs.
    American heart journal, 1990, Volume: 120, Issue:3

    Topics: Animals; Chemical Phenomena; Chemistry; Diterpenes; Dogs; Electrophysiology; Ginkgolides; Lactones; Myocardial Reperfusion Injury; Phospholipid Ethers; Platelet Activating Factor; Time Factors

1990
Adult respiratory distress syndrome: roles of leukotriene C4 and platelet activating factor.
    Critical care medicine, 1990, Volume: 18, Issue:9

    Topics: Adult; Chromones; Diterpenes; Ginkgolides; Humans; Infections; Lactones; Leukocyte Adherence Inhibition Test; Middle Aged; Platelet Activating Factor; Pulmonary Edema; Respiratory Distress Syndrome; SRS-A

1990
Interference of the PAF-acether antagonist BN 52021 with passive anaphylaxis in the guinea-pig.
    Prostaglandins, 1987, Volume: 33, Issue:2

    Topics: Airway Resistance; Anaphylaxis; Animals; Diterpenes; Female; Ginkgolides; Guinea Pigs; Histamine Release; In Vitro Techniques; Lactones; Lung; Male; Ovalbumin; Plant Extracts; Platelet Activating Factor; Thromboxane B2

1987
Platelet-activating factor primes neutrophil responses to agonists: role in promoting neutrophil-mediated endothelial damage.
    Blood, 1988, Volume: 71, Issue:4

    Topics: Benzofurans; Cell Aggregation; Cell Survival; Diterpenes; Endothelium, Vascular; Fetal Hemoglobin; Furans; Ginkgolides; Hemoglobins, Abnormal; Humans; Inflammation; Lactones; Lignans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pancreatic Elastase; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Superoxides

1988
The effects of PAF antagonists on arrhythmias and platelets during acute myocardial ischaemia and reperfusion.
    European heart journal, 1989, Volume: 10, Issue:3

    Topics: Acute Disease; Animals; Blood Gas Analysis; Cardiac Complexes, Premature; Coronary Disease; Disease Models, Animal; Diterpenes; Dogs; Drug Evaluation, Preclinical; Electrocardiography; Ginkgolides; Hemodynamics; Hydrogen-Ion Concentration; Lactones; Myocardial Reperfusion; Oxygen; Platelet Activating Factor; Platelet Count; Quinolinium Compounds; Random Allocation; Tachycardia; Time Factors; Ventricular Fibrillation

1989
Modulation by drugs of eosinophil recruitment induced by immune challenge in the rat. Possible roles of interleukin 5 and platelet-activating factor.
    International archives of allergy and applied immunology, 1989, Volume: 88, Issue:1-2

    Topics: Animals; Cell Movement; Cyclosporins; Dextrans; Diterpenes; Eosinophilia; Eosinophils; Ginkgolides; Interleukin-5; Interleukins; Lactones; Male; Oligopeptides; Peptides, Cyclic; Peritoneal Cavity; Platelet Activating Factor; Rats; Somatostatin

1989
Interstitial mononuclear cell infiltrates in experimental nephrosis: effect of PAF antagonist.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1989, Volume: 4, Issue:12

    Topics: Acetates; Animals; Antibodies, Monoclonal; Disease Models, Animal; Diterpenes; Doxorubicin; Ginkgolides; Immunoenzyme Techniques; In Vitro Techniques; Kidney; Kidney Glomerulus; Lactones; Male; Nephritis, Interstitial; Nephrotic Syndrome; Platelet Activating Factor; Proteinuria; Puromycin; Rats; Rats, Inbred Strains

1989
Platelet-activating factor in organ transplant rejection.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1989, Volume: 19

    Topics: Animals; Aorta; Arteriosclerosis; Diterpenes; Ginkgolides; Graft Rejection; Lactones; Lymphocytes; Macrophages; Male; Plant Extracts; Platelet Activating Factor; Platelet Aggregation; Rabbits

1989
Pharmacological studies on dithranol-induced irritative dermatitis in mice.
    Archives of dermatological research, 1989, Volume: 281, Issue:5

    Topics: Animals; Anthralin; Clemastine; Diterpenes; Dose-Response Relationship, Drug; Drug Eruptions; Female; Ginkgolides; Indomethacin; Lactones; Mice; Mice, Inbred Strains; Platelet Activating Factor; Skin; Superoxide Dismutase

1989
Inhibition of platelet-activating factor (PAF)-induced chemotaxis and PAF binding to human eosinophils and neutrophils by the specific ginkgolide-derived PAF antagonist, BN 52021.
    The Journal of allergy and clinical immunology, 1989, Volume: 83, Issue:1

    Topics: Albuterol; Chemotaxis, Leukocyte; Dexamethasone; Diterpenes; Eosinophils; Ginkgolides; Humans; Lactones; Nedocromil; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Quinolones; Receptors, Cell Surface; Receptors, G-Protein-Coupled

1989
Paf-induced release of spasmogens from guinea-pig lungs.
    British journal of pharmacology, 1989, Volume: 96, Issue:1

    Topics: Animals; Aspirin; Bronchi; Chromones; Diterpenes; Ginkgolides; Guinea Pigs; In Vitro Techniques; Indoles; Indomethacin; Lactones; Leukotriene B4; Lung; Masoprocol; Muscle Contraction; Muscle, Smooth; Platelet Activating Factor; SRS-A; Trachea

1989
Role of platelet activating factor in endotoxemic acute renal failure in the male rat.
    The Journal of laboratory and clinical medicine, 1989, Volume: 113, Issue:3

    Topics: Acute Kidney Injury; Animals; Blood Pressure; Diterpenes; Ginkgolides; Glomerular Filtration Rate; Indomethacin; Kidney; Lactones; Lipopolysaccharides; Male; Platelet Activating Factor; Platelet Membrane Glycoproteins; Quinolines; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Renal Circulation

1989
Release of eicosanoids in rat peritoneal cavity during the Arthus reaction. Effect of the PAF-antagonist BN-52021 and indomethacin.
    International journal of immunopharmacology, 1989, Volume: 11, Issue:2

    Topics: Animals; Arthus Reaction; Dinoprostone; Diterpenes; Ginkgolides; Guinea Pigs; Indomethacin; Lactones; Leukotriene B4; Male; Peritoneal Cavity; Platelet Activating Factor; Rats; Rats, Inbred Strains; Thromboxane B2

1989
Effect of the platelet-activating factor antagonist BN 52021 on human natural killer cell cytotoxicity.
    International archives of allergy and applied immunology, 1989, Volume: 88, Issue:1-2

    Topics: Cytotoxicity, Immunologic; Diterpenes; Ginkgolides; Humans; Immunity, Cellular; Immunity, Innate; In Vitro Techniques; Killer Cells, Natural; Lactones; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled

1989
Characterization of specific binding sites for PAF in the iris and ciliary body of rabbit.
    Biochemical and biophysical research communications, 1989, Apr-14, Volume: 160, Issue:1

    Topics: Animals; Binding, Competitive; Ciliary Body; Diterpenes; Female; Ginkgolides; Iris; Kinetics; Lactones; Male; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Tritium

1989
Presence of specific platelet-activating factor binding sites in the rat retina.
    European journal of pharmacology, 1989, Apr-12, Volume: 163, Issue:1

    Topics: Animals; Azepines; Diterpenes; Ginkgolides; In Vitro Techniques; Lactones; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Retina; Triazines; Triazoles

1989
Effects of PAF and BN 52021 on cardiac function and regional blood flow in conscious rats.
    The American journal of physiology, 1989, Volume: 257, Issue:1 Pt 2

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Diterpenes; Dose-Response Relationship, Drug; Ginkgolides; Hemodynamics; Lactones; Male; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Regional Blood Flow; Vascular Resistance

1989
The alkyl-ether phospholipid platelet-activating factor is a stimulator of the hypothalamic-pituitary-adrenal axis in the rat.
    Endocrinology, 1989, Volume: 125, Issue:2

    Topics: Adrenocorticotropic Hormone; Alprazolam; Animals; Arachidonic Acid; Arachidonic Acids; Central Nervous System; Corticosterone; Corticotropin-Releasing Hormone; Diterpenes; Ginkgolides; Hypothalamo-Hypophyseal System; Hypothalamus; Lactones; Male; Pituitary Gland; Pituitary-Adrenal System; Platelet Activating Factor; Rats; Rats, Inbred Strains; Verapamil

1989
Inhibitory effects of nedocromil sodium on the in vitro induced migration and leukotriene formation of human granulocytes.
    Drugs, 1989, Volume: 37 Suppl 1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Calcimycin; Chemotaxis, Leukocyte; Cromolyn Sodium; Diterpenes; Eosinophils; Ginkgolides; Granulocytes; Humans; In Vitro Techniques; Lactones; Leukotriene B4; Leukotrienes; Nedocromil; Neutrophils; Platelet Activating Factor; Quinolones; SRS-A; Zymosan

1989
Release of eicosanoids in rat peritoneal cavity stimulated with platelet-activating factor (PAF). Effect of the PAF-antagonist BN-52021.
    Prostaglandins, leukotrienes, and essential fatty acids, 1989, Volume: 37, Issue:1

    Topics: Animals; Dinoprostone; Diterpenes; Fatty Acids, Unsaturated; Ginkgolides; Lactones; Leukotriene B4; Peritoneal Cavity; Platelet Activating Factor; Rats; Rats, Inbred Strains; Thromboxane B2

1989
Effects of PAF and PAF antagonists on the shape of venous endothelial cells in vitro.
    Agents and actions, 1989, Volume: 28, Issue:1-2

    Topics: Animals; Calcimycin; Diterpenes; Electron Spin Resonance Spectroscopy; Endothelium, Vascular; Furans; Ginkgolides; Guinea Pigs; Lactones; Leukotriene E4; Lysophosphatidylcholines; Phospholipid Ethers; Platelet Activating Factor; SRS-A; Vena Cava, Inferior

1989
Inhibition of platelet-activating factor- and zymosan-activated serum-induced chemotaxis of human neutrophils by nedocromil sodium, BN 52021 and sodium cromoglycate.
    British journal of pharmacology, 1989, Volume: 97, Issue:4

    Topics: Calcium; Chemotaxis, Leukocyte; Cromolyn Sodium; Diterpenes; Ginkgolides; Granulocytes; Humans; In Vitro Techniques; Lactones; Nedocromil; Neutrophils; Platelet Activating Factor; Quinolones; Zymosan

1989
Possible involvement of platelet activating factor in anaphylaxis of passively sensitised, isolated guinea pig hearts.
    Cardiovascular research, 1989, Volume: 23, Issue:8

    Topics: Anaphylaxis; Animals; Coronary Circulation; Diterpenes; Dose-Response Relationship, Drug; Ginkgolides; Guinea Pigs; Hemodynamics; Immunization, Passive; Lactones; Male; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled

1989
Cryogenic induced ocular HSV-1 reactivation is enhanced by an inhibitor of the lipoxygenase pathway.
    Current eye research, 1989, Volume: 8, Issue:12

    Topics: Animals; Cornea; Corneal Injuries; Cryosurgery; Diterpenes; Ginkgolides; Hydroxyeicosatetraenoic Acids; Keratitis, Dendritic; Lactones; Lipoxygenase Inhibitors; Platelet Activating Factor; Rabbits; Random Allocation; Simplexvirus; Virus Activation; Virus Cultivation

1989
[The blocking action of platelet-activating factor (PAF) on the calcium currents of the atrial fibers in the frog and guinea pig].
    Biulleten' eksperimental'noi biologii i meditsiny, 1989, Volume: 108, Issue:12

    Topics: Animals; Atrial Function; Calcium Channel Blockers; Calcium Channels; Diterpenes; Ginkgolides; Guinea Pigs; Heart; Heart Atria; Histamine; In Vitro Techniques; Lactones; Membrane Potentials; Myocardial Contraction; Platelet Activating Factor; Rana ridibunda

1989
Involvement of platelet-activating factor (PAF) in endotoxin-induced intestinal motor disturbances in rats.
    Life sciences, 1989, Volume: 45, Issue:6

    Topics: Animals; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Diterpenes; Duodenum; Electromyography; Endotoxins; Escherichia coli; Gastrointestinal Motility; Ginkgolides; Indomethacin; Jejunum; Lactones; Male; Muscle, Smooth; Myenteric Plexus; Plant Extracts; Platelet Activating Factor; Rats; Rats, Inbred Strains; Reference Values

1989
Effects of platelet-activating factor on ion transport in isolated rat jejunum.
    The American journal of physiology, 1989, Volume: 257, Issue:5 Pt 1

    Topics: Animals; Azepines; Biological Transport; Diterpenes; Electric Conductivity; Ginkgolides; In Vitro Techniques; Ions; Jejunum; Lactones; Male; Mast Cells; Platelet Activating Factor; Rats; Rats, Inbred Strains; Thioxanthenes; Triazines; Triazoles; Xanthones

1989
Modification of allergen-induced airway obstruction and airway hyperresponsiveness in an allergic rabbit model by the selective platelet-activating factor antagonist, BN 52021.
    The Journal of allergy and clinical immunology, 1989, Volume: 84, Issue:6 Pt 1

    Topics: Airway Obstruction; Allergens; Animals; Bronchial Spasm; Diterpenes; Ginkgolides; Histamine; Lactones; Lung; Lung Compliance; Plant Extracts; Platelet Activating Factor; Rabbits; Respiratory Hypersensitivity

1989
The effect of PAF in the cochlea of guinea pigs.
    Prostaglandins, 1989, Volume: 38, Issue:5

    Topics: Acoustic Stimulation; Animals; Blood Pressure; Cochlea; Diterpenes; Electrophysiology; Evoked Potentials, Auditory; Female; Ginkgolides; Guinea Pigs; Lactones; Male; Phenylacetates; Platelet Activating Factor; Sulfonamides

1989
Endotoxin shock, kinin system and PAF-acether in the rat.
    Advances in experimental medicine and biology, 1989, Volume: 247B

    Topics: Animals; Blood Pressure; Diterpenes; Exudates and Transudates; Ginkgolides; Hematocrit; Lactones; Platelet Activating Factor; Platelet Count; Rats; Rats, Inbred BN; Rats, Inbred Strains; Shock, Septic; Species Specificity

1989
Effects of platelet activating factor (PAF) and its receptor antagonist BN 52021 on isolated perfused guinea-pig heart.
    Prostaglandins, leukotrienes, and essential fatty acids, 1989, Volume: 38, Issue:3

    Topics: Animals; Coronary Circulation; Diterpenes; Dose-Response Relationship, Drug; Ginkgolides; Guinea Pigs; Heart; Heart Function Tests; Heart Rate; In Vitro Techniques; L-Lactate Dehydrogenase; Lactones; Myocardial Contraction; Perfusion; Platelet Activating Factor

1989
Chemotactic effect of PAF-acether on peritoneal eosinophils from normal rats.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 1989, Volume: 22, Issue:9

    Topics: Animals; Azepines; Chemotactic Factors; Chemotactic Factors, Eosinophil; Chemotaxis, Leukocyte; Diterpenes; Eosinophils; Ginkgolides; In Vitro Techniques; Lactones; Male; Peritoneal Cavity; Platelet Activating Factor; Rats; Rats, Inbred Strains; Triazoles

1989
Pharmacological modulation of the bronchopulmonary action of the vasoactive peptide, endothelin, administered by aerosol in the guinea-pig.
    Biochemical and biophysical research communications, 1989, Feb-15, Volume: 158, Issue:3

    Topics: Aerosols; Animals; Blood Pressure; Bronchi; Diterpenes; Endothelins; Endothelium, Vascular; Ginkgolides; Guinea Pigs; Indomethacin; Lactones; Male; Nifedipine; Peptides; Plant Extracts; Platelet Activating Factor; Propranolol; Pyrilamine; Verapamil

1989
Endothelin has potent ulcerogenic and vasoconstrictor actions in the stomach.
    The American journal of physiology, 1989, Volume: 256, Issue:4 Pt 1

    Topics: Animals; Blood Pressure; Diterpenes; Dose-Response Relationship, Drug; Endothelins; Endothelium, Vascular; Ethanol; Ginkgolides; Hydrochloric Acid; Indomethacin; Lactones; Male; Nitroprusside; Peptic Ulcer Hemorrhage; Peptides; Platelet Activating Factor; Propionates; Quinolines; Rats; Rats, Inbred Strains; SRS-A; Stomach; Stomach Ulcer; Vasoconstriction

1989
Protective effect of the PAF-antagonist BN 52021 on several models of gastro-intestinal mucosal damage in rats.
    International journal of tissue reactions, 1989, Volume: 11, Issue:2

    Topics: Animals; Aspartate Aminotransferases; Blood Glucose; Cold Temperature; Diterpenes; Endotoxins; Escherichia coli; Gastric Mucosa; Ginkgolides; Intestinal Mucosa; Lactones; Male; Platelet Activating Factor; Rats; Rats, Inbred Strains; Restraint, Physical; Salmonella enteritidis; Time Factors

1989
Role of platelet-activating factor (PAF) in the initiation of the decidual reaction in the rat.
    Journal of reproduction and fertility, 1989, Volume: 85, Issue:2

    Topics: Animals; Decidua; Diterpenes; Female; Ginkgolides; Indomethacin; Lactones; Plant Extracts; Platelet Activating Factor; Pregnancy; Pseudopregnancy; Rats; Rats, Inbred Strains

1989
Effect of platelet-activating factor antagonist on cyclosporine nephrotoxicity. Glomerular hemodynamics evaluation.
    Transplantation, 1989, Volume: 47, Issue:4

    Topics: Animals; Cyclosporins; Diterpenes; Ginkgolides; Kidney Glomerulus; Lactones; Male; Platelet Activating Factor; Rats; Rats, Inbred Strains

1989
The effects of platelet-activating factor on flow rate and eicosanoid release in the isolated perfused rat gastric vascular bed.
    Prostaglandins, 1989, Volume: 37, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Benzofurans; Blood Flow Velocity; Chromatography, High Pressure Liquid; Chromones; Diterpenes; Gastric Mucosa; Ginkgolides; Indomethacin; Lactones; Lipoxygenase Inhibitors; Male; Masoprocol; Platelet Activating Factor; Rats; Rats, Inbred Strains; SRS-A; Stomach; Thromboxane B2

1989
Antigen-induced bronchopulmonary alterations in the guinea pig: a new model of passive sensitization mediated by mouse IgE antibodies.
    International archives of allergy and applied immunology, 1989, Volume: 89, Issue:1

    Topics: Animals; Blood Cell Count; Bronchial Spasm; Chromones; Dinitrophenols; Diterpenes; Female; Ginkgolides; Guinea Pigs; Immunization, Passive; Immunoglobulin E; Lactones; Male; Platelet Activating Factor; Pyrilamine; Serum Albumin, Bovine; SRS-A

1989
Platelet-activating factor and laser trauma of the iris.
    Investigative ophthalmology & visual science, 1989, Volume: 30, Issue:6

    Topics: Animals; Diterpenes; Dose-Response Relationship, Drug; Ginkgolides; Intraocular Pressure; Iris; Lactones; Lasers; Male; Ocular Hypertension; Plant Extracts; Platelet Activating Factor; Rabbits; Radiation Injuries, Experimental

1989
[Renal diseases and platelet activating factor].
    Pediatrie, 1989, Volume: 44, Issue:3

    Topics: Acute Kidney Injury; Anaphylaxis; Animals; Cyclosporins; Diterpenes; Ginkgolides; Glomerulonephritis; Graft Rejection; Kidney Diseases; Lactones; Plant Extracts; Platelet Activating Factor; Proteinuria; Rabbits; Rats

1989
Modulation of eosinophil recruitment in the rat by the platelet-activating factor (PAF) antagonist, BN 52021, the somatostatin analog, BIM 23014, and by cyclosporin A.
    Prostaglandins, 1989, Volume: 37, Issue:3

    Topics: Animals; Cyclophosphamide; Cyclosporins; Diterpenes; Eosinophils; Ginkgolides; Lactones; Male; Peptides, Cyclic; Platelet Activating Factor; Rats; Rats, Inbred Strains; Somatostatin

1989
Interference of WEB 2086 and BN 52021 with Paf-induced effects on guinea-pig trachea.
    British journal of pharmacology, 1989, Volume: 97, Issue:2

    Topics: Animals; Azepines; Dinoprostone; Diterpenes; Ginkgolides; Guinea Pigs; Histamine Antagonists; In Vitro Techniques; Lactones; Male; Muscle Relaxation; Muscle, Smooth; Platelet Activating Factor; Trachea; Triazines; Triazoles

1989
The effect of Paf antagonists on bronchial hyperresponsiveness induced by Paf, propranolol or indomethacin.
    British journal of pharmacology, 1989, Volume: 97, Issue:3

    Topics: Acetylcholine; Animals; Azepines; Bronchi; Diterpenes; Ginkgolides; Guinea Pigs; Histamine; In Vitro Techniques; Indomethacin; Lactones; Male; Phospholipid Ethers; Platelet Activating Factor; Propranolol; Respiratory Hypersensitivity; Triazines; Triazoles

1989
Role of leukotrienes and platelet activating factor in acute gastric mucosal lesions in rats.
    European journal of pharmacology, 1989, May-19, Volume: 164, Issue:2

    Topics: Animals; Aspirin; Chromones; Diterpenes; Ethanol; Gastric Mucosa; Ginkgolides; Lactones; Leukotrienes; Male; Masoprocol; Platelet Activating Factor; Rats; Rats, Inbred Strains; SRS-A; Stomach Ulcer; Stress, Psychological; Taurocholic Acid

1989
Ginkgolide B protects isolated hearts against arrhythmias induced by ischemia but not reperfusion.
    European journal of pharmacology, 1989, May-19, Volume: 164, Issue:2

    Topics: Animals; Arrhythmias, Cardiac; Diltiazem; Diterpenes; Ginkgolides; Heart Function Tests; Lactones; Male; Metoprolol; Myocardial Reperfusion; Perfusion; Platelet Activating Factor; Rats; Rats, Inbred Strains; Reperfusion Injury

1989
The effect of the platelet-activating factor antagonist, BN 52021, on human natural killer cell-mediated cytotoxicity.
    Immunology, 1989, Volume: 67, Issue:3

    Topics: Cells, Cultured; Cytotoxicity, Immunologic; Diterpenes; Ginkgolides; Humans; Killer Cells, Natural; Lactones; Lymphocytes; Plant Extracts; Platelet Activating Factor

1989
Arachidonic acid metabolism and cerebral blood flow in the normal, ischemic, and reperfused gerbil brain. Inhibition of ischemia-reperfusion-induced cerebral injury by a platelet-activating factor antagonist (BN 52021).
    Annals of the New York Academy of Sciences, 1989, Volume: 559

    Topics: Animals; Arachidonic Acids; Brain; Carotid Arteries; Cerebrovascular Circulation; Diterpenes; Gerbillinae; Ginkgolides; Ischemic Attack, Transient; Kinetics; Lactones; Neurons; Platelet Activating Factor; Reference Values; Reperfusion; Synaptosomes

1989
Effect of cyclosporin A and the platelet-activating factor (PAF) antagonist, BN 52021, on PAF- and antigen- induced bronchoconstriction in the guinea-pig.
    Biochemical and biophysical research communications, 1989, Aug-30, Volume: 163, Issue:1

    Topics: Animals; Antigens; Bronchial Provocation Tests; Bronchial Spasm; Cyclosporins; Diterpenes; Ginkgolides; Guinea Pigs; Immunization, Passive; In Vitro Techniques; Lactones; Leukopenia; Male; Platelet Activating Factor; Thrombocytopenia

1989
The involvement of platelet-activating factor (PAF)-induced monocyte activation and tumor necrosis factor (TNF) production in shock.
    Progress in clinical and biological research, 1989, Volume: 308

    Topics: Cytotoxicity, Immunologic; Diterpenes; Ginkgolides; Humans; Kinetics; Lactones; Monocytes; Platelet Activating Factor; Shock, Septic; Tumor Necrosis Factor-alpha

1989
Effect of PAF-antagonists in endotoxin shock--ovine and rat experiments.
    Progress in clinical and biological research, 1989, Volume: 308

    Topics: Animals; Azepines; Blood Pressure; Diterpenes; Ginkgolides; Hemodynamics; Kinetics; Lactones; Lymph; Male; Platelet Activating Factor; Proteins; Pulmonary Artery; Rats; Rats, Inbred Strains; Sheep; Shock, Septic; Triazines; Triazoles

1989
Protective effect of BN 52021, a specific antagonist of platelet-activating factor (PAF-acether) against diet-induced cholesteryl ester deposition in rabbit aorta.
    Atherosclerosis, 1989, Volume: 78, Issue:2-3

    Topics: Animals; Aorta; Arteriosclerosis; Cholesterol; Cholesterol Esters; Diet, Atherogenic; Diterpenes; Ginkgolides; Lactones; Platelet Activating Factor; Platelet Aggregation; Rabbits; Sterol Esterase; Sterol O-Acyltransferase

1989
Effect of long-term treatment with platelet-activating factor on cytokine production by rat spleen cells.
    International archives of allergy and applied immunology, 1989, Volume: 88, Issue:1-2

    Topics: Animals; Concanavalin A; Diterpenes; Ginkgolides; Interleukin-1; Interleukin-2; Lactones; Lymphocytes; Monocytes; Platelet Activating Factor; Rats; Spleen; Time Factors

1989
Selective inhibition of adrenaline-induced human platelet aggregation by the structurally related Paf antagonist Ro 19-3704.
    British journal of pharmacology, 1989, Volume: 96, Issue:4

    Topics: 5-Hydroxytryptophan; Binding, Competitive; Diterpenes; Drug Synergism; Epinephrine; Ginkgolides; Glyceryl Ethers; Humans; In Vitro Techniques; Lactones; Morpholines; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Thiazoles; Yohimbine

1989
Platelet-activating factor induces the production of leukotrienes by human monocytes.
    Biochimica et biophysica acta, 1989, Sep-04, Volume: 1013, Issue:1

    Topics: Azepines; Cells, Cultured; Chromatography, High Pressure Liquid; Diterpenes; Ginkgolides; Humans; Kinetics; Lactones; Leukotrienes; Monocytes; Plant Extracts; Platelet Activating Factor; Triazines; Triazoles

1989
Influence of inhibitors of the eicosanoid metabolism, and of eicosanoids- and PAF-acether antagonists on mortality and some biochemical parameters of three shock models.
    Progress in clinical and biological research, 1989, Volume: 301

    Topics: Anaphylaxis; Animals; Aspirin; Diterpenes; Fatty Acids, Unsaturated; Female; Ginkgolides; Imidazoles; Ketotifen; Lactones; Masoprocol; Mice; Naphthalenes; Platelet Activating Factor; Rats; Rats, Inbred Strains; Shock; Shock, Septic

1989
The relevance of eicosanoids including PAF for the biochemical regulation of cardiac rhythm.
    Progress in clinical and biological research, 1989, Volume: 301

    Topics: Alprostadil; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Azepines; Diterpenes; Dogs; Fatty Acids, Unsaturated; Female; Ginkgolides; Guinea Pigs; Heart Rate; In Vitro Techniques; Lactones; Male; Platelet Activating Factor; Sulfonamides; Triazines; Triazoles

1989
Influence of the specific antagonist of PAF-acether, BN 52021, on the rejection of murine tail skin allografts and the PAF-acether mortality in mice in particular consideration of the role of TXB2.
    Progress in clinical and biological research, 1989, Volume: 301

    Topics: Animals; Diterpenes; Female; Ginkgolides; Graft Survival; Lactones; Mice; Mice, Inbred Strains; Platelet Activating Factor; Skin Transplantation; Thromboxane B2

1989
An investigation into the possible involvement of platelet activating factor in experimental allergic encephalomyelitis in rats.
    Agents and actions, 1989, Volume: 27, Issue:3-4

    Topics: Animals; Azepines; Diterpenes; Encephalomyelitis, Autoimmune, Experimental; Female; Ginkgolides; Lactones; Platelet Activating Factor; Rats; Thienopyridines; Time Factors

1989
Platelet-activating factor: an endogenous mediator of mesenteric ischemia-reperfusion-induced shock.
    The American journal of physiology, 1989, Volume: 257, Issue:4 Pt 2

    Topics: Animals; Blood Pressure; Diterpenes; Dogs; Ginkgolides; Lactones; Male; Mesenteric Arteries; Mesenteric Vascular Occlusion; Platelet Activating Factor; Reperfusion; Splanchnic Circulation

1989
Evidence against a role for platelet-activating factor in hypoxic pulmonary vasoconstriction in the rat.
    Clinical science (London, England : 1979), 1989, Volume: 77, Issue:4

    Topics: Animals; Azepines; Diterpenes; Ginkgolides; Hypoxia; Lactones; Male; Platelet Activating Factor; Pulmonary Circulation; Rats; Rats, Inbred Strains; Triazines; Triazoles; Vasoconstriction

1989
Antagonism of platelet activating factor-induced chemiluminescence in guinea-pig peritoneal macrophages in differing states of activation.
    British journal of pharmacology, 1989, Volume: 98, Issue:2

    Topics: Alprazolam; Animals; Benzofurans; Diterpenes; Furans; Ginkgolides; Guinea Pigs; In Vitro Techniques; Lactones; Lignans; Luminescent Measurements; Macrophage Activation; Macrophages; Male; Platelet Activating Factor; Thiazoles

1989
Inhibition of the metabolism of platelet activating factor (PAF-acether) by three specific antagonists from Ginkgo biloba.
    Biochemical pharmacology, 1987, Sep-01, Volume: 36, Issue:17

    Topics: Animals; Diterpenes; Dose-Response Relationship, Drug; Ginkgolides; Lactones; Male; Membrane Proteins; Plant Extracts; Platelet Activating Factor; Platelet Aggregation; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled

1987
PAF binding sites. Characterization by [3H]52770 RP, a pyrrolo[1,2-c]thiazole derivative, in rabbit platelets.
    Biochemical pharmacology, 1987, Oct-01, Volume: 36, Issue:19

    Topics: Animals; Blood Platelets; Diterpenes; Furans; Ginkgolides; In Vitro Techniques; Kinetics; Lactones; Male; Plant Extracts; Platelet Activating Factor; Platelet Aggregation; Platelet Membrane Glycoproteins; Pyridines; Rabbits; Radioligand Assay; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Stereoisomerism; Thiazoles; Triazolam; Tritium

1987
Inhibition by BN 52021 (ginkgolide B) of the binding of [3H]-platelet-activating factor to human neutrophil granulocytes.
    Biochemical and biophysical research communications, 1987, Nov-13, Volume: 148, Issue:3

    Topics: Diterpenes; Dose-Response Relationship, Drug; Exocytosis; Ginkgolides; Lactones; Neutrophils; Plant Extracts; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Superoxides

1987
Proof of the involvement of platelet activating factor (paf-acether) in pulmonary complex immune systems using a specific paf-acether receptor antagonist: BN 52021.
    Progress in lipid research, 1986, Volume: 25, Issue:1-4

    Topics: Anaphylaxis; Animals; Bronchial Spasm; Diterpenes; Ginkgolides; Guinea Pigs; In Vitro Techniques; Lactones; Lung; Male; Plant Extracts; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled

1986
Effects of a platelet activating factor antagonist (BN 52021) on free fatty acids, diacylglycerols, polyphosphoinositides and blood flow in the gerbil brain: inhibition of ischemia-reperfusion induced cerebral injury.
    Biochemical and biophysical research communications, 1987, Dec-16, Volume: 149, Issue:2

    Topics: Animals; Blood Pressure; Brain Chemistry; Brain Ischemia; Cerebrovascular Circulation; Diglycerides; Diterpenes; Fatty Acids, Nonesterified; Gerbillinae; Ginkgolides; Lactones; Phosphatidylinositol Phosphates; Phosphatidylinositols; Plant Extracts; Platelet Activating Factor

1987
The accumulation of platelet activating factor in the injured cornea may be interrelated with the synthesis of lipoxygenase products.
    Biochemical and biophysical research communications, 1987, Dec-31, Volume: 149, Issue:3

    Topics: Alprazolam; Animals; Arachidonic Acids; Burns, Chemical; Cornea; Corneal Injuries; Diterpenes; Ginkgolides; Lactones; Lipoxygenase; Lipoxygenase Inhibitors; Luminescent Measurements; Plant Extracts; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled

1987
Modulation of leucocyte activation in the early phase of the rabbit burn injury.
    Burns, including thermal injury, 1988, Volume: 14, Issue:1

    Topics: Animals; Burns; Calcimycin; Disease Models, Animal; Diterpenes; Free Radicals; Ginkgolides; Lactones; Leukotriene B4; Male; Neutrophils; Platelet Activating Factor; Rabbits; Superoxides

1988
Platelet-activating factor antagonist BN52021 decreases accumulation of free polyunsaturated fatty acid in mouse brain during ischemia and electroconvulsive shock.
    Journal of neurochemistry, 1988, Volume: 51, Issue:6

    Topics: Animals; Brain; Brain Ischemia; Chromatography; Diglycerides; Dimethyl Sulfoxide; Diterpenes; Electroshock; Fatty Acids, Nonesterified; Ginkgolides; Lactones; Male; Mice; Mice, Inbred BALB C; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Plant Extracts; Platelet Activating Factor

1988
Characterization of receptors for platelet-activating factor on platelets, polymorphonuclear leukocytes and macrophages.
    British journal of pharmacology, 1988, Volume: 94, Issue:4

    Topics: Animals; Azepines; Blood Platelets; Calcimycin; Cell Aggregation; Diterpenes; Epoprostenol; Furans; Ginkgolides; In Vitro Techniques; Lactones; Macrophages; Male; Neutrophils; Platelet Activating Factor; Platelet Aggregation; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Triazines; Triazoles

1988
Comparison of three paf-acether receptor antagonist ginkgolides.
    European journal of pharmacology, 1988, Jul-26, Volume: 152, Issue:1-2

    Topics: Adenosine Triphosphate; Binding, Competitive; Blood Platelets; Diterpenes; Ginkgolides; Humans; In Vitro Techniques; Lactones; Male; Platelet Activating Factor; Platelet Aggregation; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled

1988
Specific receptor sites for PAF in iris and ciliary body of the rabbit eye.
    Current eye research, 1988, Volume: 7, Issue:11

    Topics: Animals; Ciliary Body; Diterpenes; Female; Ginkgolides; In Vitro Techniques; Iris; Kinetics; Lactones; Male; Molecular Structure; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled

1988
Involvement of platelet activating factor in respiratory anaphylaxis, demonstrated by PAF-acether inhibitor BN 52021.
    Lancet (London, England), 1985, Jun-29, Volume: 1, Issue:8444

    Topics: Animals; Asthma; Bronchi; Diterpenes; Ginkgolides; Guinea Pigs; Humans; Lactones; Male; Plant Extracts; Platelet Activating Factor

1985
Gossypol: a potent inhibitor of PAF-acether- and leukotriene-induced contractions of guinea-pig lung parenchyma strips.
    The Journal of pharmacy and pharmacology, 1987, Volume: 39, Issue:6

    Topics: Animals; Diterpenes; Ginkgolides; Gossypol; Guinea Pigs; Histamine Antagonists; In Vitro Techniques; Lactones; Leukotriene B4; Lung; Male; Masoprocol; Muscle Contraction; Plant Extracts; Platelet Activating Factor; Respiratory Muscles; SRS-A

1987
The involvement of platelet activating factor in ovulation.
    Science (New York, N.Y.), 1989, Jan-20, Volume: 243, Issue:4889

    Topics: Animals; Capillary Permeability; Collagen; Diterpenes; Female; Ginkgolides; Lactones; Ovary; Ovulation; Platelet Activating Factor; Rats

1989
Increased levels of platelet-activating factor in blood following intestinal ischemia in the dog.
    Biochemical and biophysical research communications, 1989, Jan-31, Volume: 158, Issue:2

    Topics: Animals; Blood Pressure; Diterpenes; Dogs; Ginkgolides; Ischemia; Lactones; Platelet Activating Factor; Shock; Splanchnic Circulation

1989
Effect of ginkgolide PAF-acether antagonists on arterial thrombosis.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1987, Volume: 17B

    Topics: Animals; Diterpenes; Embolism; Ginkgolides; Guinea Pigs; Lactones; Male; Mesenteric Arteries; Plant Extracts; Platelet Activating Factor; Thrombosis

1987
Immune complex induced pancreatitis: effect of BN 52021, a selective antagonist of platelet-activating factor.
    Prostaglandins, 1988, Volume: 35, Issue:5

    Topics: Animals; Capillary Permeability; Disease Models, Animal; Diterpenes; Ginkgolides; Immune Complex Diseases; Lactones; Male; Pancreatitis; Platelet Activating Factor; Rats; Rats, Inbred Strains

1988
Inhibition of transmembrane movement and metabolism of platelet activating factor (PAF-acether) by a specific antagonist, BN 52021.
    Biochemical and biophysical research communications, 1985, Oct-30, Volume: 132, Issue:2

    Topics: Animals; Biological Transport, Active; Blood Platelets; Cell Membrane; Diterpenes; Ginkgolides; Lactones; Phosphatidylcholines; Plant Extracts; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled

1985
Interference of BN 52021 (ginkgolide B) with the bronchopulmonary effects of PAF-acether in the guinea-pig.
    European journal of pharmacology, 1986, Aug-07, Volume: 127, Issue:1-2

    Topics: Animals; Blood Platelets; Blood Pressure; Bronchi; Diterpenes; Ginkgolides; Guinea Pigs; In Vitro Techniques; Lactones; Leukocytes; Lung; Male; Muscle Contraction; Plant Extracts; Platelet Activating Factor; Superoxides; Thromboxane B2

1986
Characterization of platelet activating factor (PAF)-acether-induced contractions of guinea-pig lung strips by selected inhibitors of arachidonic acid metabolism and by PAF-acether antagonists.
    Immunopharmacology, 1986, Volume: 12, Issue:2

    Topics: Animals; Aspirin; Benzofurans; Chromones; Diterpenes; Ginkgolides; Guinea Pigs; Histamine; Imidazoles; Lactones; Leukotriene B4; Lignans; Lung; Male; Methacrylates; Muscle Contraction; Muscle, Smooth; Plant Extracts; Platelet Activating Factor; Prostaglandin Antagonists; Pyrilamine; SRS-A

1986
Stimulus amplification by PAF and LTB4 in human neutrophils.
    Pharmacological research communications, 1986, Volume: 18 Suppl

    Topics: Calcium; Chemotaxis, Leukocyte; Diterpenes; Drug Synergism; Ginkgolides; Humans; In Vitro Techniques; Lactones; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Plant Extracts; Platelet Activating Factor

1986
Species difference in the specific receptors of platelet activating factor.
    Biochemical pharmacology, 1986, Dec-15, Volume: 35, Issue:24

    Topics: Animals; Benzofurans; Blood Platelets; Cell Membrane; Diterpenes; Furans; Ginkgolides; Humans; Lactones; Lignans; Lung; Phospholipid Ethers; Plant Extracts; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Species Specificity; Thiazoles; Thiophenes

1986
Changes in cytosolic free calcium induced by platelet-activating factor in rabbit platelets: specific inhibition by BN 52021 and structurally related compounds.
    Agents and actions. Supplements, 1986, Volume: 20

    Topics: Aminoquinolines; Animals; Blood Platelets; Calcium; Cytosol; Diterpenes; Dose-Response Relationship, Drug; Ginkgolides; Lactones; Plant Extracts; Platelet Activating Factor; Platelet Aggregation; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Spectrometry, Fluorescence; Structure-Activity Relationship

1986
Effects of platelet activating factor on the chemotaxis of normodense eosinophils from normal subjects.
    Biochemical and biophysical research communications, 1987, Feb-13, Volume: 142, Issue:3

    Topics: Adult; Chemotactic Factors, Eosinophil; Chemotaxis, Leukocyte; Diterpenes; Eosinophils; Ginkgolides; Humans; Lactones; Leukotriene B4; Male; Plant Extracts; Platelet Activating Factor

1987
Hemodynamic effects of PAF-acether on the dog kidney.
    Prostaglandins, leukotrienes, and medicine, 1987, Volume: 26, Issue:3

    Topics: Animals; Blood Pressure; Diterpenes; Diuresis; Dogs; Female; Ginkgolides; Glomerular Filtration Rate; Indomethacin; Kidney; Lactones; Plant Extracts; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Renal Circulation; Sodium

1987
Antagonism of vasoconstriction induced by platelet-activating factor in guinea-pig perfused hearts by selective platelet-activating factor receptor antagonists.
    British journal of pharmacology, 1987, Volume: 90, Issue:4

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Chromones; Coronary Vessels; Diterpenes; Furans; Ginkgolides; Guinea Pigs; In Vitro Techniques; Indomethacin; Lactones; Leukotriene B4; Male; Perfusion; Plant Extracts; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; SRS-A; Thromboxane A2; Time Factors; Vasoconstriction

1987
Desensitization and antagonism of rat polymorphonuclear leukocytes stimulated with PAF acether.
    Prostaglandins, 1987, Volume: 33, Issue:1

    Topics: Animals; Cells, Cultured; Cytochalasin B; Diterpenes; Exocytosis; Ginkgolides; Glucuronidase; Lactones; Leukotriene B4; Male; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Plant Extracts; Platelet Activating Factor; Pyridines; Rats; Rats, Inbred Strains; Thiazoles

1987
Effects of platelet-activating factor on electrophysiology of isolated retinas and their inhibition by BN 52021, a specific PAF-acether receptor antagonist.
    Immunopharmacology, 1987, Volume: 13, Issue:3

    Topics: Animals; Diterpenes; Electrophysiology; Electroretinography; Ginkgolides; In Vitro Techniques; Lactones; Plant Extracts; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Retina

1987
Effects of the specific platelet-activating factor antagonists, BN 52021 and BN 52063, on various experimental gastrointestinal ulcerations.
    European journal of pharmacology, 1988, Jun-10, Volume: 150, Issue:3

    Topics: Animals; Anti-Ulcer Agents; Aspirin; Diterpenes; Endotoxins; Ethanol; Female; Gastric Mucosa; Ginkgolides; Humans; In Vitro Techniques; Intestinal Mucosa; Lactones; Male; Plant Extracts; Platelet Activating Factor; Pylorus; Rats; Rats, Inbred Strains; Salmonella enteritidis; Stomach Ulcer

1988
Influence of the specific antagonist of PAF-acether, BN 52021, and of Ginkgo extract on the rejection of murine tail skin allografts and the PAF-acether mortality in mice in particular consideration of the role of TXB2.
    Biomedica biochimica acta, 1988, Volume: 47, Issue:10-11

    Topics: Animals; Diterpenes; Ginkgolides; Graft Rejection; Lactones; Mice; Plant Extracts; Platelet Activating Factor; Reference Values; Regeneration; Skin; Skin Transplantation; Thromboxane B2; Transplantation, Homologous

1988
Specific inhibition of PAF-acether-induced platelet activation by BN 52021 and comparison with the PAF-acether inhibitors kadsurenone and CV 3988.
    European journal of pharmacology, 1986, Apr-16, Volume: 123, Issue:2

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Arachidonic Acid; Arachidonic Acids; Benzofurans; Benzopyrans; Blood Platelets; Diterpenes; Ginkgolides; Humans; In Vitro Techniques; Lactones; Lignans; Phospholipid Ethers; Plant Extracts; Platelet Activating Factor; Platelet Aggregation; Thiazoles

1986
Inhibitory effects of a novel platelet activating factor (PAF) antagonist (BN 52021) on antigen-induced prostaglandin and thromboxane formation by the guinea pig lung.
    Pharmacological research communications, 1986, Volume: 18 Suppl

    Topics: Anaphylaxis; Animals; Arachidonic Acid; Arachidonic Acids; Dinoprostone; Diterpenes; Female; Ginkgolides; Guinea Pigs; In Vitro Techniques; Kinetics; Lactones; Lung; Male; Ovalbumin; Plant Extracts; Platelet Activating Factor; Prostaglandins; Prostaglandins E; Thromboxane B2; Thromboxanes

1986
Protection by two ginkgolides, BN-52020 and BN-52021, against guinea-pig lung anaphylaxis.
    Pharmacological research communications, 1986, Volume: 18, Issue:9

    Topics: Anaphylaxis; Animals; Arachidonic Acid; Arachidonic Acids; Blood Pressure; Diterpenes; Dose-Response Relationship, Drug; Ginkgolides; Guinea Pigs; Lactones; Lung; Male; Perfusion; Plant Extracts; Platelet Activating Factor; Thromboxane B2

1986
Antagonists of PAF-acether do not suppress thrombin-induced aggregation of ADP-deprived and aspirin-treated human platelets.
    Agents and actions, 1987, Volume: 21, Issue:1-2

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aspirin; Blood Platelets; Crotalid Venoms; Cyclooxygenase Inhibitors; Diterpenes; Ginkgolides; Glyceryl Ethers; Humans; Lactones; Lectins, C-Type; Phospholipid Ethers; Plant Extracts; Platelet Activating Factor; Platelet Aggregation; Pyridines; Thiazoles; Thrombin

1987
Effect of platelet activating factor antagonists on cultured rat mesangial cells.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 243, Issue:2

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Benzofurans; Calcimycin; Cells, Cultured; Dinoprostone; Diterpenes; Dose-Response Relationship, Drug; Ginkgolides; Glomerular Mesangium; Lactones; Lignans; Male; Plant Extracts; Platelet Activating Factor; Prostaglandins E; Rats; Thiazoles

1987
Role of platelet-activating factor (PAF) in the ovoimplantation in the rat: effect of the specific PAF-acether antagonist, BN 52021.
    Prostaglandins, 1988, Volume: 35, Issue:2

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Catechols; Diterpenes; Dose-Response Relationship, Drug; Embryo Implantation; Female; Ginkgolides; Indomethacin; Kinetics; Lactones; Lipoxygenase Inhibitors; Masoprocol; Platelet Activating Factor; Pyrazoles; Rats; Rats, Inbred Strains; Sulfides

1988
Antagonism of PAF-induced death in mice.
    Prostaglandins, 1988, Volume: 35, Issue:3

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Bridged Bicyclo Compounds, Heterocyclic; Collagen; Diterpenes; Epinephrine; Fatty Acids, Unsaturated; Furans; Ginkgolides; Hydrazines; Lactones; Male; Mice; Platelet Activating Factor; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Pyridines; Thiazoles; Thromboxane A2

1988
Role of paf-acether in the mediation of pathophysiological responses to aggregated immunoglobulins. Studies with the platelet-activating factor receptor antagonist BN 52021.
    International journal of immunopharmacology, 1988, Volume: 10, Issue:4

    Topics: Acetylglucosaminidase; Animals; Diterpenes; Ginkgolides; Humans; Immunoglobulin G; Lactones; Metabolic Clearance Rate; Neutropenia; Platelet Activating Factor; Rats; Rats, Inbred Strains; Tissue Plasminogen Activator

1988
Inhibition of the alkali burn-induced lipoxygenation of arachidonic acid in the rabbit cornea in vivo by a platelet activating factor antagonist.
    Journal of ocular pharmacology, 1987,Winter, Volume: 3, Issue:4

    Topics: Alkalies; Animals; Aqueous Humor; Arachidonic Acid; Arachidonic Acids; Burns, Chemical; Cornea; Diterpenes; Eye Burns; Eye Proteins; Female; Ginkgolides; Hydroxyeicosatetraenoic Acids; Lactones; Lipoxygenase; Male; Membrane Lipids; Phospholipids; Platelet Activating Factor; Rabbits

1987
Release of platelet-activating factor (PAF) and accelerated healing induced by a PAF antagonist in an animal model of chronic colitis.
    Canadian journal of physiology and pharmacology, 1988, Volume: 66, Issue:4

    Topics: Animals; Colitis; Disease Models, Animal; Diterpenes; Ginkgolides; Lactones; Male; Platelet Activating Factor; Rabbits; Rats; Rats, Inbred Strains; Trinitrobenzenesulfonic Acid

1988
PAF-acether and endotoxin display similar effects on rat mesenteric microvessels: inhibition by specific antagonists.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 247, Issue:1

    Topics: Animals; Azepines; Blood Pressure; Diterpenes; Endotoxins; Ginkgolides; Lactones; Male; Microcirculation; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Rats; Rats, Inbred Strains; Splanchnic Circulation; Triazines; Triazoles

1988
Platelet activating factor induces dopamine release in PC-12 cell line.
    The American journal of physiology, 1988, Volume: 255, Issue:4 Pt 1

    Topics: Adrenal Gland Neoplasms; Animals; Atropine; Calcium; Carbachol; Cell Line; Diterpenes; Dopamine; Ginkgolides; Kinetics; Lactones; Pheochromocytoma; Phospholipid Ethers; Platelet Activating Factor

1988
Platelet activating factor antagonism with BN52021 protects the kidney against acute ischemic injury.
    Prostaglandins, leukotrienes, and essential fatty acids, 1988, Volume: 34, Issue:1

    Topics: Acute Kidney Injury; Animals; Diterpenes; Female; Ginkgolides; Lactones; Platelet Activating Factor; Rats

1988
PAF increases vascular permeability in selected tissues: effect of BN-52021 and L-655,240.
    Prostaglandins, 1988, Volume: 36, Issue:5

    Topics: Animals; Capillary Permeability; Diterpenes; Evans Blue; Ginkgolides; Indoles; Lactones; Male; Plant Extracts; Platelet Activating Factor; Rats; Rats, Inbred Strains; Reference Values; Thromboxanes; Tissue Distribution

1988
BN-52021 protects guinea-pig from heart anaphylaxis.
    Pharmacological research communications, 1988, Volume: 20 Suppl 5

    Topics: Anaphylaxis; Animals; Diterpenes; Ginkgolides; Guinea Pigs; Heart; Heart Rate; Histamine; Lactones; Male; Platelet Activating Factor; Thromboxane B2

1988
The effects of PAF antagonists on ischaemia and reperfusion arrhythmias and ischaemia-induced platelet aggregation.
    Biomedica biochimica acta, 1988, Volume: 47, Issue:10-11

    Topics: Animals; Coronary Disease; Diterpenes; Dogs; Female; Ginkgolides; Heart; Lactones; Male; Myocardial Reperfusion Injury; Platelet Activating Factor; Platelet Aggregation; Quinolinium Compounds

1988
Release of cysteinyl-leukotrienes is of minor importance in PAF induced reduction of perfusion rate in the gastric vascular bed.
    Biomedica biochimica acta, 1988, Volume: 47, Issue:10-11

    Topics: Animals; Chromones; Cysteine; Diterpenes; Ginkgolides; Indomethacin; Lactones; Leukotrienes; Male; Masoprocol; Platelet Activating Factor; Rats; Rats, Inbred Strains; Splanchnic Circulation; SRS-A; Stomach

1988
Potentiation of immunosuppressive action of cyclosporine A by platelet-activating factor antagonists: an approach of the mechanism of action of these drugs in the prevention of graft rejection.
    Transplantation proceedings, 1988, Volume: 20, Issue:2 Suppl 2

    Topics: Animals; Cyclosporins; Diterpenes; Drug Synergism; Ginkgolides; Immunosuppression Therapy; In Vitro Techniques; Interleukin-1; Interleukin-2; Lactones; Leukocytes, Mononuclear; Lymphocyte Activation; Mitogens; Plant Extracts; Platelet Activating Factor; Rats; Spleen; Time Factors

1988
Evidence for platelet-activating factor as a mediator of endotoxin-induced gastrointestinal damage in the rat. Effects of three platelet-activating factor antagonists.
    Gastroenterology, 1987, Volume: 93, Issue:4

    Topics: Animals; Blood Pressure; Disease Models, Animal; Diterpenes; Escherichia coli Infections; Ethanol; Ginkgolides; Glyceryl Ethers; Intestine, Small; Lactones; Lipopolysaccharides; Male; Peptic Ulcer; Peptic Ulcer Hemorrhage; Phospholipid Ethers; Plant Extracts; Platelet Activating Factor; Rats; Rats, Inbred Strains; Shock, Septic; Stomach; Thiazoles

1987
Effect of platelet-activating factor (PAF-acether) and its specific receptor antagonist, BN 52021, on interleukin 1 (IL1) release and synthesis by rat spleen adherent monocytes.
    Prostaglandins, 1987, Volume: 33, Issue:6

    Topics: Animals; Cells, Cultured; Diterpenes; Escherichia coli; Ginkgolides; Interleukin-1; Lactones; Lipopolysaccharides; Monocytes; Plant Extracts; Platelet Activating Factor; Rats; Rats, Inbred Strains; Spleen

1987
Pulmonary hypertension and edema induced by platelet-activating factor in isolated, perfused rat lungs are blocked by BN52021.
    The Journal of laboratory and clinical medicine, 1988, Volume: 111, Issue:2

    Topics: Animals; Diterpenes; Edema; Furans; Ginkgolides; Hypertension, Pulmonary; Injections, Intra-Arterial; Lactones; Lung; Male; Organ Size; Perfusion; Platelet Activating Factor; Rats; Rats, Inbred Strains

1988
Protection of platelet-activating factor-induced acute renal failure by BN 52021.
    British journal of experimental pathology, 1988, Volume: 69, Issue:2

    Topics: Acute Kidney Injury; Animals; Basement Membrane; Diterpenes; Ginkgolides; Glomerular Filtration Rate; Kidney Glomerulus; Lactones; Male; Microscopy, Electron; Platelet Activating Factor; Rats; Rats, Inbred Strains; Urodynamics

1988
Effect of BN 52021, a platelet activating factor antagonist, on experimental murine contact dermatitis.
    The British journal of dermatology, 1988, Volume: 118, Issue:4

    Topics: Animals; Dermatitis, Contact; Dinitrofluorobenzene; Disease Models, Animal; Diterpenes; Female; Ginkgolides; Lactones; Mice; Mice, Inbred BALB C; Platelet Activating Factor; Skin

1988
The effect of the selective PAF antagonist BN 52021 on PAF- and antigen-induced bronchial hyper-reactivity and eosinophil accumulation.
    European journal of pharmacology, 1988, Mar-22, Volume: 148, Issue:1

    Topics: Animals; Antigens; Asthma; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Diterpenes; Eosinophils; Ginkgolides; Guinea Pigs; Lactones; Male; Ovalbumin; Platelet Activating Factor

1988
Possible involvement of platelet-activating factor in endotoxin-induced abortion.
    Progress in clinical and biological research, 1988, Volume: 272

    Topics: Abortion, Spontaneous; Animals; Diterpenes; Endotoxins; Female; Ginkgolides; Gonadotropins, Equine; Lactones; Methysergide; Mice; Platelet Activating Factor; Pre-Eclampsia; Pregnancy

1988
Biosynthesis of paf-acether factor-acether by human skin fibroblasts in vitro.
    Journal of immunology (Baltimore, Md. : 1950), 1988, Aug-01, Volume: 141, Issue:3

    Topics: Adult; Diterpenes; Fibroblasts; Ginkgolides; Humans; Lactones; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein Precursors; Skin

1988
BN 52021 displaces [3H]paf-acether from, and inhibits its binding to intact human platelets.
    European journal of pharmacology, 1987, Oct-27, Volume: 142, Issue:3

    Topics: Binding, Competitive; Blood Platelets; Buffers; Diterpenes; Female; Filtration; Ginkgolides; Humans; In Vitro Techniques; Lactones; Platelet Activating Factor; Protein Binding; Serum Albumin

1987
Involvement of platelet-activating factor (PAF) in cerebral post-ischemic phase in Mongolian gerbils.
    Prostaglandins, 1987, Volume: 34, Issue:3

    Topics: Animals; Brain; Brain Ischemia; Carotid Arteries; Diterpenes; Gerbillinae; Ginkgolides; Lactones; Male; Mitochondria; Oxygen Consumption; Plant Extracts; Platelet Activating Factor; Structure-Activity Relationship

1987
The effect of the specific PAF antagonist BN 52021 and the calcium blocker diltiazem on PAF induced arrhythmogenicity.
    Pharmacological research communications, 1987, Volume: 19, Issue:10

    Topics: Administration, Oral; Animals; Arrhythmias, Cardiac; Diltiazem; Diterpenes; Ginkgolides; Guinea Pigs; In Vitro Techniques; Injections, Intravenous; Lactones; Ouabain; Platelet Activating Factor

1987
Inhibition of human lymphocyte proliferation and interleukin 2 production by platelet activating factor (PAF-acether): reversal by a specific antagonist, BN 52021.
    Biochemical and biophysical research communications, 1987, Feb-13, Volume: 142, Issue:3

    Topics: Adult; Cells, Cultured; Dinoprostone; Diterpenes; Ginkgolides; Humans; Indomethacin; Interleukin-2; Lactones; Lymphocyte Activation; Lymphocytes; Phytohemagglutinins; Plant Extracts; Platelet Activating Factor; Prostaglandins E; Thromboxane B2

1987
In vivo inhibition of plasma protein leakage and Salmonella enteritidis-induced mortality in the rat by a specific paf-acether antagonist: BN 52021.
    Agents and actions, 1986, Volume: 17, Issue:3-4

    Topics: Animals; Blood Proteins; Capillary Permeability; Diterpenes; Ginkgolides; Lactones; Male; Plant Extracts; Platelet Activating Factor; Rats; Rats, Inbred Strains; Salmonella enteritidis; Salmonella Infections, Animal; Shock, Septic

1986
Prolongation of cardiac allograft survival with BN 52021, a specific antagonist of platelet-activating factor.
    Transplantation, 1986, Volume: 42, Issue:1

    Topics: Animals; Azathioprine; Cyclosporins; Diterpenes; Ginkgolides; Graft Rejection; Graft Survival; Heart Transplantation; Immunity, Cellular; Lactones; Plant Extracts; Platelet Activating Factor; Rats; Rats, Inbred BN; Rats, Inbred Lew; Time Factors; Transplantation, Homologous

1986
Interference of the PAF-acether antagonist BN 52021 with endotoxin-induced hypotension in the guinea-pig.
    Prostaglandins, 1986, Volume: 32, Issue:6

    Topics: Animals; Diterpenes; Female; Ginkgolides; Guinea Pigs; Hypotension; Lactones; Male; Plant Extracts; Platelet Activating Factor; Shock, Septic; Thrombocytopenia

1986
Effect of BN 52021, a specific antagonist of platelet activating factor (PAF-acether), on calcium movements and phosphatidic acid production induced by PAF-acether in human platelets.
    Thrombosis research, 1987, Feb-15, Volume: 45, Issue:4

    Topics: Aminoquinolines; Blood Platelets; Calcium; Diterpenes; Dose-Response Relationship, Drug; Enzyme Activation; Ginkgolides; Humans; Lactones; Phosphatidic Acids; Phosphorus Radioisotopes; Plant Extracts; Platelet Activating Factor; Platelet Aggregation; Type C Phospholipases

1987
Inhibition of rat endotoxin-induced lethality by BN 52021 and BN 52063, compounds with PAF-acether antagonistic effect and protease-inhibitory activity.
    International journal of tissue reactions, 1987, Volume: 9, Issue:1

    Topics: Animals; Diterpenes; Endotoxins; Ginkgolides; Lactones; Male; Phospholipases A; Plant Extracts; Platelet Activating Factor; Protease Inhibitors; Rats; Rats, Inbred Strains; Shock, Septic; Trypsin

1987
Effects of PAF-acether on electrophysiological response of isolated retina.
    International journal of tissue reactions, 1987, Volume: 9, Issue:1

    Topics: Animals; Calcium; Diterpenes; Dose-Response Relationship, Drug; Electroretinography; Ginkgolides; In Vitro Techniques; Lactones; Plant Extracts; Platelet Activating Factor; Rats; Retina

1987
Evaluation of PAF antagonists using human neutrophils in a microtiter plate assay.
    Biochemical pharmacology, 1987, Aug-01, Volume: 36, Issue:15

    Topics: Benzofurans; Diterpenes; Exocytosis; Fluorescence; Ginkgolides; Humans; Lactones; Lignans; Methods; Neutrophils; Pancreatic Elastase; Phospholipid Ethers; Plant Extracts; Platelet Activating Factor; Pyridines; Thiazoles

1987
Protective effect of a PAF-acether antagonist, BN 52021, in trichothecene toxicosis.
    Toxicology letters, 1987, Volume: 38, Issue:3

    Topics: Animals; Diterpenes; Ginkgolides; Lactones; Male; Plant Extracts; Platelet Activating Factor; Rats; Rats, Inbred Strains; Sesquiterpenes; T-2 Toxin

1987
Inhibition of antigen-induced lung anaphylaxis in the guinea-pig by BN 52021 a new specific paf-acether receptor antagonist isolated from Ginkgo biloba.
    Agents and actions, 1986, Volume: 17, Issue:3-4

    Topics: Anaphylaxis; Animals; Bronchi; Chromones; Diterpenes; Ginkgolides; Guinea Pigs; Lactones; Male; Plant Extracts; Platelet Activating Factor

1986
Effects of the platelet-activating factor antagonist BN 52021 on the hemodynamics of rats with experimental cirrhosis of the liver.
    Life sciences, 1986, Jul-21, Volume: 39, Issue:3

    Topics: Animals; Blood Pressure; Cardiac Output; Diterpenes; Ginkgolides; Hemodynamics; Lactones; Liver Cirrhosis, Experimental; Plant Extracts; Platelet Activating Factor; Rats; Vascular Resistance

1986
Involvement of K+ movements in the membrane signal induced by PAF-acether.
    Biochemical pharmacology, 1986, Aug-15, Volume: 35, Issue:16

    Topics: Animals; Biological Transport, Active; Cell Membrane Permeability; Cesium; Diterpenes; Erythrocytes; Ginkgolides; Humans; Kinetics; Lactones; Lithium; Macrophages; Membrane Potentials; Mice; Models, Biological; Plant Extracts; Platelet Activating Factor; Potassium; Sodium

1986
The effects of PAF-acether on the cardiovascular system and their inhibition by a new highly specific PAF-acether receptor antagonist BN 52021.
    Pharmacological research communications, 1986, Volume: 18, Issue:8

    Topics: Animals; Blood Pressure; Capillary Permeability; Diterpenes; Drug Antagonism; Ginkgolides; Guinea Pigs; Hemodynamics; In Vitro Techniques; Kinetics; Lactones; Male; Muscle, Smooth, Vascular; Myocardial Contraction; Plant Extracts; Platelet Activating Factor; Portal Vein; Rabbits; Rats; Rats, Inbred Strains

1986
A study with BN 52021 demonstrates the involvement of PAF-acether in IgE-dependent anaphylactic bronchoconstriction.
    Prostaglandins, 1986, Volume: 32, Issue:1

    Topics: Aerosols; Anaphylaxis; Animals; Blood Platelets; Diterpenes; Female; Ginkgolides; Guinea Pigs; Immunoglobulin E; Lactones; Male; Neutrophils; Ovalbumin; Plant Extracts; Platelet Activating Factor; Propranolol

1986
Thrombus induction by endogenic paf-acether and its inhibition by Ginkgo Biloba extracts in the guinea pig.
    Prostaglandins, 1986, Volume: 32, Issue:1

    Topics: Animals; Diterpenes; Ginkgolides; Guinea Pigs; Lactones; Male; Plant Extracts; Plants, Medicinal; Platelet Activating Factor; Thrombosis

1986
Mechanism of PAF-induced platelet aggregation in man.
    Thrombosis research, 1986, Aug-15, Volume: 43, Issue:4

    Topics: Adult; Aspirin; Blood Platelets; Calcium Channel Blockers; Diterpenes; Female; Ginkgolides; Humans; Kinetics; Lactones; Male; Masoprocol; Plant Extracts; Platelet Activating Factor; Platelet Aggregation; Thromboxane B2; Trifluoperazine

1986
Pharmacological control of the in vivo passive anaphylactic shock by the PAF-acether antagonist compound BN 52021.
    Pharmacological research communications, 1986, Volume: 18 Suppl

    Topics: Anaphylaxis; Animals; Bronchi; Diterpenes; Ginkgolides; Guinea Pigs; Lactones; Plant Extracts; Platelet Activating Factor; Propranolol; Pyrilamine; Thrombocytopenia

1986
Evidence of a role for PAF-acether in the pathophysiology of the shock state.
    Pharmacological research communications, 1986, Volume: 18 Suppl

    Topics: Animals; Blood Pressure; Diterpenes; Ginkgolides; Hemodynamics; Humans; Immunoglobulin G; Lactones; Mice; Plant Extracts; Platelet Activating Factor; Rats; Shock

1986
Interference of BN 52021, a PAF-acether antagonist, with endotoxin-induced hypotension in the guinea-pig.
    Pharmacological research communications, 1986, Volume: 18 Suppl

    Topics: Animals; Blood Platelets; Blood Pressure; Diterpenes; Endotoxins; Ginkgolides; Guinea Pigs; Hypotension; Lactones; Plant Extracts; Platelet Activating Factor; Shock, Septic

1986
Crystal and molecular structure of BN 52021, a PAF-acether antagonist. Comparison with the conformation of Kadsurenone and related compounds.
    Pharmacological research communications, 1986, Volume: 18 Suppl

    Topics: Benzofurans; Chemical Phenomena; Chemistry, Physical; Crystallization; Diterpenes; Ginkgolides; Lactones; Lignans; Molecular Conformation; Plant Extracts; Platelet Activating Factor; Temperature

1986
The relative role of PAF-acether and icosanoids in septic shock.
    Pharmacological research communications, 1986, Volume: 18 Suppl

    Topics: Animals; Anti-Inflammatory Agents; Diterpenes; Eicosanoic Acids; Ginkgolides; Lactones; Male; Plant Extracts; Platelet Activating Factor; Rats; Rats, Inbred Strains; Shock, Septic

1986
Effect of BN 52021, a specific PAF-acether antagonist, on cardiac anaphylaxis in Langendorff hearts isolated from passively sensitized guinea-pigs.
    European journal of pharmacology, 1986, Oct-14, Volume: 130, Issue:1-2

    Topics: Anaphylaxis; Animals; Blood Pressure; Diterpenes; Ginkgolides; Heart; Heart Rate; In Vitro Techniques; Lactones; Myocardial Contraction; Plant Extracts; Platelet Activating Factor; Rabbits

1986
Inhibition of the vascular actions of IgG aggregates by BN 52021, a highly specific antagonist of paf-acether.
    Immunopharmacology, 1985, Volume: 10, Issue:2

    Topics: Anaphylaxis; Animals; Capillary Permeability; Diterpenes; Ginkgolides; Hypotension; Immunoglobulin G; Lactones; Plant Extracts; Platelet Activating Factor; Rats; Rats, Inbred Strains

1985
The effect of 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine (paf-acether) on the arterial wall.
    Prostaglandins, 1985, Volume: 30, Issue:2

    Topics: Adenosine Diphosphate; Alprostadil; Animals; Arteries; Diterpenes; Edetic Acid; Epoprostenol; Ginkgolides; Guinea Pigs; In Vitro Techniques; Lactones; Male; Microscopy, Electron; Microscopy, Electron, Scanning; Plant Extracts; Platelet Activating Factor; Platelet Aggregation; Quinacrine; Thrombosis

1985
Cardiac electrophysiologic and ultrastructural effects of platelet-activating factor and its antagonist BN 52021.
    Transplantation proceedings, 1995, Volume: 27, Issue:5

    Topics: Action Potentials; Animals; Cell Membrane; Diterpenes; Female; Fibrinolytic Agents; Ginkgolides; Guinea Pigs; Heart; In Vitro Techniques; Lactones; Male; Mitochondria, Heart; Myocardium; Platelet Activating Factor

1995
Increased platelet activating factor synthesis in experimental colitis after diclofenac and 5-amino-salicylic acid.
    European journal of pharmacology, 1993, Nov-02, Volume: 249, Issue:1

    Topics: Aminosalicylic Acid; Animals; Colitis; Dextrans; Diclofenac; Diterpenes; Female; Ginkgolides; Lactones; Mice; Mice, Inbred BALB C; Platelet Activating Factor; Prednisolone

1993
Human endothelial cells are targets for platelet-activating factor (PAF). Activation of alpha and beta protein kinase C isozymes in endothelial cells stimulated by PAF.
    The Journal of biological chemistry, 1994, Jan-28, Volume: 269, Issue:4

    Topics: Actins; Amino Acid Sequence; Antibodies; Cell Membrane; Cells, Cultured; Chromatography, Ion Exchange; Cytoskeletal Proteins; Cytosol; Diglycerides; Diterpenes; Endothelium, Vascular; Enzyme Activation; Ginkgolides; Humans; Isoenzymes; Kinetics; Lactones; Molecular Sequence Data; Naphthalenes; Peptides; Phospholipid Ethers; Platelet Activating Factor; Polycyclic Compounds; Protein Kinase C; Protein Kinase Inhibitors; Tetradecanoylphorbol Acetate; Thiazoles; Vinculin

1994
Capsaicin sensitive nerves in the jejunum of Nippostrongylus brasiliensis-sensitized rats participate in a cardiovascular depressor reflex.
    Naunyn-Schmiedeberg's archives of pharmacology, 1993, Volume: 348, Issue:6

    Topics: Anaphylaxis; Animals; Animals, Newborn; Blood Pressure; Capsaicin; Diterpenes; Ginkgolides; Guanethidine; Hemodynamics; Indomethacin; Jejunum; Lactones; Male; Neurons, Afferent; Nippostrongylus; Platelet Activating Factor; Pyrilamine; Rats; Rats, Sprague-Dawley; Reflex; Ruthenium Red; Strongylida Infections

1993
Platelet-activating factor mediates pancreatic function derangement in caerulein-induced pancreatitis in rats.
    Clinical science (London, England : 1979), 1994, Volume: 87, Issue:1

    Topics: Acute Disease; Amylases; Animals; Ascitic Fluid; Ceruletide; Cholecystokinin; Diterpenes; Ginkgolides; Lactones; Male; Pancreas; Pancreatitis; Platelet Activating Factor; Rats; Rats, Wistar

1994
Platelet activating factor potentiates rat paw oedema induced by different phlogogen agents.
    Agents and actions, 1994, Volume: 41, Issue:3-4

    Topics: Animals; Bradykinin; Carrageenan; Cellulose; Dextrans; Dinoprostone; Diterpenes; Drug Synergism; Edema; Ginkgolides; Histamine; Inflammation Mediators; Lactones; Male; p-Methoxy-N-methylphenethylamine; Platelet Activating Factor; Rats; Rats, Wistar; Serotonin; Verapamil

1994
Effect of atrial natriuretic peptide and calcium antagonists on platelet-activating factor-induced contraction and intracellular calcium mobilization in rat mesangial cells.
    Journal of cardiovascular pharmacology, 1994, Volume: 24, Issue:3

    Topics: Analysis of Variance; Animals; Atrial Natriuretic Factor; Calcium; Calcium Channel Blockers; Cells, Cultured; Diterpenes; Dose-Response Relationship, Drug; Fura-2; Furans; Gallic Acid; Ginkgolides; Glomerular Mesangium; Hydrogen-Ion Concentration; Lactones; Muscle Contraction; Muscle, Smooth; Platelet Activating Factor; Rats; Rats, Wistar; Spectrometry, Fluorescence; Verapamil

1994
Effect of PAF antagonists on cerulein-induced pancreatitis.
    Journal of lipid mediators and cell signalling, 1995, Volume: 11, Issue:1

    Topics: Acute Disease; Amylases; Animals; Azepines; Capillary Permeability; Ceruletide; Diterpenes; Evans Blue; Ginkgolides; Lactones; Male; Pancreas; Pancreatitis; Platelet Activating Factor; Rats; Rats, Wistar; Triazoles

1995
The effect of platelet activating factor antagonist (BN 52021) on acute experimental pancreatitis with reference to multiorgan oxidative stress.
    International journal of pancreatology : official journal of the International Association of Pancreatology, 1995, Volume: 17, Issue:2

    Topics: Acute Disease; Amylases; Animals; Disease Models, Animal; Diterpenes; Ginkgolides; Lactones; Liver; Lung; Male; Malondialdehyde; Organ Specificity; Oxidative Stress; Pancreas; Pancreatitis; Platelet Activating Factor; Rats; Rats, Wistar; Sulfhydryl Compounds

1995
Modulation of signal transduction in rat synaptoneurosomes by platelet activating factor.
    Molecular and chemical neuropathology, 1995, Volume: 25, Issue:1

    Topics: Animals; Calcium; Colforsin; Cyclic AMP; Diterpenes; Enzyme Activation; Fibrinolytic Agents; Fluorescent Dyes; Fura-2; Ginkgolides; Hippocampus; Immunoblotting; Lactones; Platelet Activating Factor; Protein Kinase C; Rats; Signal Transduction; Subcellular Fractions; Synaptosomes

1995
Role of platelet activating factor in kidney transplant rejection in the rat.
    Kidney international, 1995, Volume: 48, Issue:2

    Topics: Animals; Diterpenes; Ginkgolides; Glomerular Filtration Rate; Graft Rejection; Kidney; Kidney Transplantation; Lactones; Leukotriene E4; Male; Plant Extracts; Platelet Activating Factor; Rats; Rats, Inbred ACI; Rats, Inbred Strains; Renal Circulation; Thromboxane B2

1995
Sea urchins--a new model for PAF research in embryology.
    Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 1995, Volume: 110, Issue:3

    Topics: Animals; Diterpenes; Fertilization; Ginkgolides; Lactones; Male; Models, Biological; Platelet Activating Factor; Sea Urchins; Sperm Motility

1995
Stimulation of calcium influx by platelet activating factor in Dictyostelium.
    Journal of cell science, 1995, Volume: 108 ( Pt 4)

    Topics: 4-Chloro-7-nitrobenzofurazan; Animals; Calcium; Cell Membrane; Cyclic AMP; Dictyostelium; Diterpenes; Dose-Response Relationship, Drug; Estrenes; Ginkgolides; GTP-Binding Proteins; Inositol 1,4,5-Trisphosphate; Kinetics; Lactones; Platelet Activating Factor; Pyrrolidinones; Species Specificity; Time Factors

1995
Possible role of platelet-activating factor in embryonic signaling during oviductal transport in the hamster.
    Biology of reproduction, 1995, Volume: 52, Issue:6

    Topics: Animals; Cricetinae; Culture Techniques; Diterpenes; Embryo, Mammalian; Female; Ginkgolides; Indomethacin; Isoquinolines; Lactones; Masoprocol; Ovum Transport; Platelet Activating Factor; Platelet Count; Pregnancy; Pyridinium Compounds; Signal Transduction; Tetrahydroisoquinolines

1995
Gentamicin activates rat mesangial cells. A role for platelet activating factor.
    Kidney international, 1995, Volume: 47, Issue:5

    Topics: Alprazolam; Animals; Base Sequence; Calcium; Cell Division; Cells, Cultured; Diterpenes; Genes, fos; Gentamicins; Ginkgolides; Glomerular Filtration Rate; Glomerular Mesangium; Lactones; Leucine; Molecular Sequence Data; Platelet Activating Factor; Rats; Rats, Wistar; RNA, Messenger

1995
Release of platelet activating factor (PAF) and eicosanoids in UVC-irradiated corneal stromal cells.
    Current eye research, 1995, Volume: 14, Issue:5

    Topics: Animals; Arachidonic Acids; Cells, Cultured; Corneal Stroma; Diterpenes; Dose-Response Relationship, Radiation; Eicosanoids; Fibrinolytic Agents; Ginkgolides; Lactones; Phospholipids; Plant Extracts; Platelet Activating Factor; Rabbits; Radioimmunoassay; Ultraviolet Rays

1995
Lack of platelet-activating factor release on acute myocardial ischemia in the isolated interventricular septum of rabbit heart.
    European journal of pharmacology, 1995, May-26, Volume: 293, Issue:1

    Topics: Acute Disease; Animals; Chromatography, High Pressure Liquid; Diterpenes; Fibrinolytic Agents; Ginkgolides; Heart Ventricles; In Vitro Techniques; Lactones; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Platelet Activating Factor; Rabbits

1995
Platelet-activating factor antagonist and cardiopulmonary bypass.
    The Annals of thoracic surgery, 1995, Volume: 60, Issue:3

    Topics: Animals; Atrial Function, Left; Blood Pressure; Cardiopulmonary Bypass; Disease Models, Animal; Diterpenes; Fibrinolytic Agents; Ginkgolides; Humans; Lactones; Lung; Platelet Activating Factor; Pulmonary Artery; Swine; Vascular Resistance

1995
Platelet-activating factor antagonists (BN 52021 and BN 50730) inhibit tumor necrosis factor-alfa-mediated cytotoxicity on murine L929 tumor cells.
    Molecular immunology, 1993, Volume: 30, Issue:6

    Topics: Animals; Aprotinin; Azepines; Cytotoxicity, Immunologic; Diterpenes; Dose-Response Relationship, Immunologic; Ginkgolides; Lactones; Mice; Platelet Activating Factor; Tetrazoles; Thienopyridines; Triazoles; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

1993
PAF antagonist, BN52021, inhibits [3H]D-aspartate release after ischaemia in vitro.
    Neuroreport, 1994, Dec-30, Volume: 6, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Aspartic Acid; Brain Ischemia; Diterpenes; Enzyme Activation; Ginkgolides; Hippocampus; In Vitro Techniques; Isoquinolines; Lactones; Phorbol 12,13-Dibutyrate; Piperazines; Platelet Activating Factor; Potassium; Protein Kinase C; Rats; Rats, Wistar; Tritium

1994
Involvement of platelet activating factor in microcirculatory disturbances after global hepatic ischemia.
    The Journal of surgical research, 1995, Volume: 58, Issue:5

    Topics: Adenosine Triphosphate; Animals; Bile; Diterpenes; Ginkgolides; Ischemia; Lactones; Liver Circulation; Male; Microcirculation; Osmolar Concentration; Platelet Activating Factor; Rats; Rats, Wistar; Reperfusion

1995
Memory enhancement by intrahippocampal, intraamygdala, or intraentorhinal infusion of platelet-activating factor measured in an inhibitory avoidance task.
    Proceedings of the National Academy of Sciences of the United States of America, 1995, May-23, Volume: 92, Issue:11

    Topics: Amygdala; Animals; Avoidance Learning; Diterpenes; Ginkgolides; Habituation, Psychophysiologic; Hippocampus; In Vitro Techniques; Infusions, Parenteral; Lactones; Long-Term Potentiation; Male; Memory; Platelet Activating Factor; Pyramidal Cells; Rats; Rats, Wistar; Reference Values; Space Perception; Time Factors

1995
Desensitization of platelet-activating factor receptors, induced by inflammation in guinea pig ileal smooth muscle cells.
    Gastroenterology, 1995, Volume: 108, Issue:6

    Topics: Acetylcholine; Animals; Cell Survival; Dinoprostone; Diterpenes; Ginkgolides; Guinea Pigs; Ileitis; Ileum; Indomethacin; Lactones; Male; Muscle Contraction; Muscle, Smooth; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Prostaglandin E; Trinitrobenzenesulfonic Acid

1995
Presence of specific platelet-activating factor binding-sites in neuroblastoma N1E-115 cells.
    Neuroscience letters, 1995, Feb-17, Volume: 186, Issue:2-3

    Topics: Animals; Azepines; Binding Sites; Binding, Competitive; Brain Neoplasms; Diterpenes; Ginkgolides; Kinetics; Lactones; Mice; Neuroblastoma; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thienopyridines; Triazoles; Tumor Cells, Cultured

1995
[The role of platelet activating factor in mesenterioangial microcirculatory disturbance complicated with acute pancreatitis in rats].
    Zhonghua yi xue za zhi, 1995, Volume: 75, Issue:3

    Topics: Acute Disease; Animals; Diterpenes; Ginkgolides; Lactones; Male; Microcirculation; Pancreatitis; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Shock, Septic; Splanchnic Circulation; Taurocholic Acid

1995
Myocardial ischaemia induces platelet activation with adverse electrophysiological and arrhythmogenic effects.
    Cardiovascular research, 1994, Volume: 28, Issue:11

    Topics: Animals; Arrhythmias, Cardiac; Aspirin; Biphenyl Compounds; Blood Platelets; Colforsin; Diterpenes; Electrophysiology; Ginkgolides; Guinea Pigs; Heart; Heptanoic Acids; Lactones; Male; Myocardial Ischemia; Oxidopamine; Platelet Activating Factor; Platelet Activation; Platelet Aggregation Inhibitors; Receptors, Thromboxane; Yohimbine

1994
Treatment of preservation/reperfusion injury by platelet-activating factor antagonism in the rat liver graft.
    Transplantation proceedings, 1995, Volume: 27, Issue:1

    Topics: Animals; Diterpenes; Ginkgolides; L-Lactate Dehydrogenase; Lactones; Liver; Liver Transplantation; Male; Neutrophils; Organ Preservation; Peroxidase; Platelet Activating Factor; Rats; Rats, Wistar; Reperfusion Injury

1995
The effect of platelet activating factor antagonist (BN 52021) on pregnancy duration and collagen content in the pregnant rat uterus and cervix.
    Endocrine research, 1994, Volume: 20, Issue:4

    Topics: Animals; Collagen; Diterpenes; Female; Gestational Age; Ginkgolides; Lactones; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pregnancy; Pregnancy, Animal; Rats; Rats, Wistar; Uterus

1994
Interactions of constitutive nitric oxide with PAF and thromboxane on rat intestinal vascular integrity in acute endotoxaemia.
    British journal of pharmacology, 1994, Volume: 113, Issue:4

    Topics: Animals; Azepines; Blood Pressure; Capillaries; Capillary Permeability; Cyclooxygenase Inhibitors; Diterpenes; Escherichia coli; Ginkgolides; Intestinal Mucosa; Intestines; Lactones; Lipopolysaccharides; Male; Nitric Oxide; Phenylephrine; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Thromboxane; Thromboxane A2; Triazoles

1994
Effect of platelet activating factor antagonists in different models of thrombosis.
    Thrombosis research, 1994, Dec-15, Volume: 76, Issue:6

    Topics: Animals; Arterial Occlusive Diseases; Azepines; Cats; Diterpenes; Ginkgolides; Lactones; Male; Mice; Mice, Inbred Strains; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Thiazoles; Thrombophlebitis; Triazoles

1994
Role of platelet activating factor in the intestinal epithelial secretory and Chinese hamster ovary cell cytoskeletal responses to cholera toxin.
    Proceedings of the National Academy of Sciences of the United States of America, 1994, Sep-27, Volume: 91, Issue:20

    Topics: Animals; CHO Cells; Cholera Toxin; Cricetinae; Cytoskeleton; Diterpenes; Epithelium; Ginkgolides; Ileum; In Vitro Techniques; Indomethacin; Intestinal Mucosa; Lactones; Male; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thiazoles

1994
Effect of antagonists of platelet-activating factor receptors on memory of inhibitory avoidance in rats.
    Behavioral and neural biology, 1994, Volume: 62, Issue:1

    Topics: Amygdala; Animals; Avoidance Learning; Diterpenes; Ginkgolides; Glutamates; Hippocampus; Lactones; Male; Memory; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Synaptic Membranes

1994
[Effect of BN52021 on platelet activating factor induced aggregation of psoriatic polymorphonuclear neutrophils].
    Zhonghua yi xue za zhi, 1994, Volume: 74, Issue:6

    Topics: Adult; Aged; Cell Aggregation; Diterpenes; Female; Ginkgolides; Humans; Lactones; Male; Middle Aged; Neutrophils; Platelet Activating Factor; Psoriasis

1994
Eicosanoid and inositol phosphate response to platelet-activating factor (PAF) and to a PAF antagonist in rat astroglial cells.
    Brain research. Developmental brain research, 1994, Apr-15, Volume: 78, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Animals, Newborn; Astrocytes; Calcimycin; Cells, Cultured; Diterpenes; Dose-Response Relationship, Drug; Eicosanoids; Ginkgolides; Inositol; Inositol Phosphates; Kinetics; Lactones; Platelet Activating Factor; Rats; Thromboxane B2

1994
Hyperalgesia induced by Bothrops jararaca venom in rats: role of eicosanoids and platelet activating factor (PAF).
    Toxicon : official journal of the International Society on Toxinology, 1994, Volume: 32, Issue:4

    Topics: Animals; Azepines; Bothrops; Crotalid Venoms; Dexamethasone; Diterpenes; Dose-Response Relationship, Drug; Eicosanoids; Fibrinolytic Agents; Ginkgolides; Hyperalgesia; Indomethacin; Lactones; Male; Platelet Activating Factor; Rats; Rats, Wistar; Triazoles

1994
Effect of the platelet activating factor antagonist BN52021 in rabbits: role in gentamicin nephrotoxicity.
    Toxicology and applied pharmacology, 1994, Volume: 128, Issue:1

    Topics: Animals; Diterpenes; Dose-Response Relationship, Drug; Electrolytes; Gentamicins; Ginkgolides; Glomerular Filtration Rate; Injections, Subcutaneous; Kidney; Kidney Function Tests; Lactones; Male; Models, Biological; Platelet Activating Factor; Rabbits

1994
Platelet-activating factor antagonists reduce excitotoxic damage in cultured neurons from embryonic chick telencephalon and protect the rat hippocampus and neocortex from ischemic injury in vivo.
    Journal of neuroscience research, 1993, Feb-01, Volume: 34, Issue:2

    Topics: Animals; Cells, Cultured; Cerebral Cortex; Chick Embryo; Diterpenes; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Ginkgolides; Glutamates; Glutamic Acid; Hippocampus; Ischemic Attack, Transient; Lactones; Male; Neurons; Platelet Activating Factor; Rats; Rats, Wistar; Telencephalon

1993
Antagonists and inhibitors of lipid mediators in experimental inflammation of the cornea.
    Journal of ocular pharmacology, 1993,Winter, Volume: 9, Issue:4

    Topics: Animals; Chromones; Diterpenes; Eicosapentaenoic Acid; Fluorometholone; Ginkgolides; Keratitis; Lactones; Linolenic Acids; Lipids; Lipoxygenase Inhibitors; Male; Platelet Activating Factor; Rabbits; SRS-A; Suprofen

1993
Platelet-activating factor as a potential retrograde messenger in CA1 hippocampal long-term potentiation.
    Nature, 1994, Jan-13, Volume: 367, Issue:6459

    Topics: Action Potentials; Animals; Azepines; Diterpenes; Ginkgolides; Hippocampus; In Vitro Techniques; Lactones; Long-Term Potentiation; Male; Phospholipid Ethers; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Tetrazoles; Thienopyridines; Triazoles

1994
Systemic and regional hemodynamic changes during endotoxin or platelet activating factor (PAF)-induced shock in rats.
    Circulatory shock, 1993, Volume: 41, Issue:4

    Topics: Animals; Diterpenes; Endotoxins; Ginkgolides; Hemodynamics; Lactones; Male; Platelet Activating Factor; Rats; Rats, Wistar; Regional Blood Flow; Shock, Septic; Vascular Resistance

1993
Involvement of tumor necrosis factor and platelet-activating factor in the pathogenesis of experimental nephrosis in rats.
    Laboratory investigation; a journal of technical methods and pathology, 1994, Volume: 70, Issue:4

    Topics: Animals; Cell Death; Cells, Cultured; Diterpenes; Doxorubicin; Female; Ginkgolides; Kidney Glomerulus; Lactones; Nephrosis; Platelet Activating Factor; Platelet Membrane Glycoproteins; Proteinuria; Puromycin Aminonucleoside; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Tumor Necrosis Factor-alpha

1994
A platelet-activating factor antagonist reduces corneal allograft inflammation and neovascularization.
    Current eye research, 1994, Volume: 13, Issue:2

    Topics: Animals; Cornea; Corneal Edema; Corneal Neovascularization; Corneal Transplantation; Diterpenes; Eosinophilia; Female; Ginkgolides; Graft Rejection; Keratitis; Lactones; Male; Platelet Activating Factor; Rabbits; Transplantation, Autologous; Transplantation, Homologous

1994
Enhanced eosinophil luminol-dependent chemiluminescence and complement receptor expression by platelet-activating factor and interleukin-5.
    Asian Pacific journal of allergy and immunology, 1993, Volume: 11, Issue:1

    Topics: Asthma; Diterpenes; Eosinophils; Ginkgolides; Humans; Interleukin-5; Lactones; Luminescent Measurements; Luminol; Macrophage-1 Antigen; Phagocytosis; Platelet Activating Factor; Receptors, Complement; Receptors, Complement 3b; Rhinitis; Time Factors

1993
Platelet-activating factor (PAF)-induced cardiopulmonary dysfunctions and their reversal with a PAF antagonist (BN 52021) in strain 13 guinea pigs.
    Journal of lipid mediators, 1993, Volume: 7, Issue:3

    Topics: Animals; Blood Pressure; Cardiac Output; Cardiovascular Diseases; Diterpenes; Ginkgolides; Guinea Pigs; Lactones; Lung; Male; Platelet Activating Factor; Respiratory Tract Diseases; Ventricular Function, Left

1993
Platelet-activating factor antagonism enhances the liver's recovery from warm ischemia in situ.
    Journal of hepatology, 1993, Volume: 18, Issue:3

    Topics: Adenosine Triphosphate; Animals; Diterpenes; Endothelium, Vascular; Free Radicals; Ginkgolides; Ischemia; Lactones; Liver; Male; Malondialdehyde; Platelet Activating Factor; Purine-Nucleoside Phosphorylase; Rats; Rats, Wistar; Reperfusion Injury

1993
Calcium channel blockers inhibit hydrogen peroxide-induced proliferation of cultured rat mesangial cells.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 267, Issue:2

    Topics: Animals; Calcium Channel Blockers; Cell Count; Cell Division; Cells, Cultured; Diltiazem; Diterpenes; Ginkgolides; Glomerular Mesangium; Hydrogen Peroxide; Kinetics; Lactones; Platelet Activating Factor; Platelet-Derived Growth Factor; Rats; Rats, Wistar; Thrombin; Thymidine; Tritium; Verapamil

1993
Involvement of oxygen free radicals in the action of BN 52021 (PAF antagonist) to limit myocardial infarct size.
    Methods and findings in experimental and clinical pharmacology, 1993, Volume: 15, Issue:7

    Topics: Analysis of Variance; Animals; Blood Pressure; Diterpenes; Electrocardiography; Female; Free Radicals; Ginkgolides; Glutathione Peroxidase; Heart Ventricles; Lactones; Luminescent Measurements; Male; Malondialdehyde; Myocardial Infarction; Myocardium; Neutrophils; Platelet Activating Factor; Rats; Rats, Inbred Strains

1993
Heparin or a PAF antagonist (BN-52021) prevents the acute pulmonary edema induced by Tityus serrulatus scorpion venom in the rat.
    Toxicon : official journal of the International Society on Toxinology, 1993, Volume: 31, Issue:9

    Topics: Animals; Diterpenes; Ginkgolides; Heparin; Hypertension; Lactones; Male; Platelet Activating Factor; Pulmonary Edema; Rats; Rats, Wistar; Scorpion Venoms

1993
Reduction of conjugated dienes in lung transplantation: effect of BN 52021.
    The Annals of thoracic surgery, 1993, Volume: 56, Issue:6

    Topics: Animals; Chromatography, High Pressure Liquid; Diterpenes; Dogs; Free Radicals; Ginkgolides; Lactones; Lung; Lung Transplantation; Male; Platelet Activating Factor

1993
Differential sensitivity of mouse strains to platelet activating factor-induced vasopermeability and mortality: effect of antagonists.
    Journal of lipid mediators, 1993, Volume: 8, Issue:3

    Topics: Animals; Azepines; Capillary Permeability; Coloring Agents; Diterpenes; Evans Blue; Ginkgolides; Lactones; Mice; Mice, Inbred A; Mice, Inbred BALB C; Platelet Activating Factor; Species Specificity; Triazoles

1993
Lipid mediator production in acute and chronic pancreatitis in the rat.
    The Journal of surgical research, 1994, Volume: 56, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Acute Disease; Animals; Chronic Disease; Dinoprostone; Diterpenes; Eicosanoids; Ginkgolides; Lactones; Leukotriene B4; Ligation; Male; Masoprocol; Pancreatic Ducts; Pancreatitis; Platelet Activating Factor; Prostaglandin D2; Rats; Rats, Sprague-Dawley; Taurocholic Acid; Thromboxane B2

1994
Effect of a platelet-activating factor antagonist and desferrioxamine administration on eicosanoid production in rat pancreas transplantation.
    Transplantation, 1994, Volume: 57, Issue:1

    Topics: Animals; Deferoxamine; Diterpenes; Eicosanoids; Ginkgolides; Lactones; Male; Pancreas Transplantation; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Reperfusion Injury

1994
The effect of a platelet activating factor antagonist (BN 52021) on neurologic outcome and histopathology in a canine model of complete cerebral ischemia.
    Anesthesiology, 1993, Volume: 79, Issue:2

    Topics: Animals; Brain Ischemia; Disease Models, Animal; Diterpenes; Dogs; Ginkgolides; Hemodynamics; Injections, Intravenous; Lactones; Platelet Activating Factor

1993
Protective effect of the PAF antagonist BN 52021 in an experimental renal warm ischemia model.
    Transplant international : official journal of the European Society for Organ Transplantation, 1993, Volume: 6, Issue:4

    Topics: Animals; Creatinine; Disease Models, Animal; Diterpenes; Ginkgolides; Hypertonic Solutions; Infusions, Intravenous; Infusions, Parenteral; Kidney Diseases; Kidney Function Tests; Lactones; Male; Nephrectomy; Plant Extracts; Platelet Activating Factor; Rats; Rats, Wistar; Reperfusion Injury; Sodium

1993
Short-term and long-term role of platelet activating factor as a mediator of in vivo platelet aggregation.
    Circulation, 1993, Volume: 88, Issue:3

    Topics: Animals; Blood Flow Velocity; Carotid Artery Thrombosis; Coronary Thrombosis; Diterpenes; Dogs; Female; Ginkgolides; Lactones; Leukocytes; Male; Plant Extracts; Platelet Activating Factor; Platelet Aggregation; Rabbits; Regional Blood Flow; Time Factors

1993
Platelet-activating factor antagonist BN52021 improves survival in normothermic liver ischemia in rats.
    Transplantation proceedings, 1993, Volume: 25, Issue:4

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Bilirubin; Diterpenes; Dose-Response Relationship, Drug; Ginkgolides; Graft Survival; Ischemia; Lactones; Liver Circulation; Liver Transplantation; Male; Necrosis; Platelet Activating Factor; Rats; Rats, Wistar; Reperfusion Injury

1993
CIS-19, a novel platelet activating factor receptor antagonist: in vitro and in vivo studies.
    Biochimica et biophysica acta, 1993, Jan-17, Volume: 1175, Issue:2

    Topics: Adenosine Triphosphate; Animals; Blood Platelets; Bronchoconstriction; Diterpenes; Dose-Response Relationship, Drug; Ginkgolides; Guinea Pigs; Hypotension; Inositol Phosphates; Lactones; Male; Platelet Activating Factor; Rabbits; Rats; Rats, Wistar; Receptors, Cell Surface; Tetrahydronaphthalenes; Thromboxane B2

1993
Role of PAF in the allergic pleurisy caused by ovalbumin in actively sensitized rats.
    Journal of leukocyte biology, 1993, Volume: 53, Issue:1

    Topics: Analysis of Variance; Animals; Azepines; Chemotactic Factors, Eosinophil; Diterpenes; Drug Hypersensitivity; Eosinophils; Female; Freund's Adjuvant; Ginkgolides; Inflammation; Lactones; Leukocyte Count; Male; Oligopeptides; Ovalbumin; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pleurisy; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Triazoles

1993
PAF-induced death in NMRI mice--a suitable shock model for testing new PAF receptor antagonists. Correlation with eicosanoid related substances.
    Prostaglandins, leukotrienes, and essential fatty acids, 1993, Volume: 48, Issue:3

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Azepines; Disease Models, Animal; Diterpenes; Eicosanoids; Female; Ginkgolides; Lactones; Masoprocol; Mice; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Shock; Species Specificity; Triazoles

1993
An in vitro method for assessing the effects of pro-inflammatory and anti-inflammatory compounds on microvascular permeability in the rat small intestine.
    Journal of pharmacological and toxicological methods, 1993, Volume: 29, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Capillary Permeability; Carbon; Diterpenes; Drug Evaluation, Preclinical; Ginkgolides; In Vitro Techniques; Inflammation; Intestine, Small; Lactones; Male; Perfusion; Plant Extracts; Platelet Activating Factor; Rats; Rats, Sprague-Dawley

1993
Autocrine amplification of PAF-acether formation in immunologically activated murine macrophages.
    Journal of leukocyte biology, 1993, Volume: 54, Issue:4

    Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Animals; Azepines; Cells, Cultured; Chromatography, High Pressure Liquid; Diterpenes; Female; Ginkgolides; Kinetics; Lactones; Macrophage Activation; Macrophages, Peritoneal; Mice; Mice, Inbred C57BL; Mycobacterium bovis; Platelet Activating Factor; Triazoles

1993
Antagonist of platelet-activating factor prevents prostaglandin E2 induced ocular hypertension in rabbits.
    Prostaglandins, 1993, Volume: 45, Issue:1

    Topics: Animals; Dinoprostone; Diterpenes; Dose-Response Relationship, Drug; Ginkgolides; Intraocular Pressure; Kinetics; Lactones; Male; Platelet Activating Factor; Rabbits

1993
Platelet-activating factor and cerebral vasospasm following subarachnoid hemorrhage.
    Journal of neurosurgery, 1993, Volume: 78, Issue:4

    Topics: Animals; Disease Models, Animal; Diterpenes; Female; Ginkgolides; Immunoglobulin G; Ischemic Attack, Transient; Lactones; Platelet Activating Factor; Pyridinium Compounds; Rabbits; Subarachnoid Hemorrhage

1993
Luminol-chemiluminescence in free peritoneal cells in hemorrhagic shock in rats treated with PAF-receptor-antagonist BN 52021.
    Roczniki Akademii Medycznej w Bialymstoku (1995), 1995, Volume: 40, Issue:1

    Topics: Analysis of Variance; Animals; Ascitic Fluid; Diterpenes; Female; Ginkgolides; Lactones; Luminescent Measurements; Luminol; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Shock, Hemorrhagic; Tetradecanoylphorbol Acetate

1995
Ginkgolide BN 52021 protects against hemorrhagic shock-induced renal injury in rats.
    Roczniki Akademii Medycznej w Bialymstoku (1995), 1995, Volume: 40, Issue:1

    Topics: Acute Kidney Injury; Animals; Diterpenes; Female; Ginkgolides; Kidney Tubules; Lactones; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Shock, Hemorrhagic

1995
Oxygen-derived free radicals in kidney in experimental hemorrhagic shock treated by PAF-receptor antagonist BN 52021.
    Roczniki Akademii Medycznej w Bialymstoku (1995), 1995, Volume: 40, Issue:1

    Topics: Analysis of Variance; Animals; Diterpenes; Female; Free Radicals; Ginkgolides; Glutathione Reductase; Kidney; Lactones; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Shock, Hemorrhagic; Sulfhydryl Compounds; Superoxide Dismutase

1995
Plasma mediated neutrophil stimulation during coronary angioplasty: autocrine effect of platelet activating factor.
    British heart journal, 1995, Volume: 74, Issue:6

    Topics: Angioplasty, Balloon, Coronary; Azepines; CD18 Antigens; Cells, Cultured; Coronary Circulation; Diterpenes; Femoral Artery; Femoral Vein; Ginkgolides; Humans; Lactones; Myocardial Ischemia; Neutrophil Activation; Neutrophils; Platelet Activating Factor; Superoxides; Triazoles

1995
Effects of liposome-entrapped platelet-activating factor in the isolated rat trachea.
    European journal of pharmacology, 1995, Jul-25, Volume: 281, Issue:1

    Topics: Animals; Cytoplasm; Diterpenes; Drug Carriers; Epithelium; Evans Blue; Fibrinolytic Agents; Ginkgolides; Heparin; In Vitro Techniques; Kinetics; Lactones; Liposomes; Male; Muscle Contraction; Muscle, Smooth; Platelet Activating Factor; Rats; Trachea

1995
Pyrido[2,3-d]pyrimidin-4(3H)-one derivatives and 1,2,3,4-tetrahydro- pyrido[2,3-d]pyrimidine derivatives: synthesis and in vitro study of their activity against platelet aggregation.
    Die Pharmazie, 1995, Volume: 50, Issue:11

    Topics: Arachidonic Acid; Collagen; Diterpenes; Fibrinolytic Agents; Ginkgolides; Humans; In Vitro Techniques; Lactones; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyrimidines; Pyrimidinones; Serotonin; Spectrophotometry, Infrared

1995
Factors associated with hyperdynamic or hypodynamic circulation and role of platelet-activating factor in hemodynamic alterations in bacterial peritonitis in conscious rats.
    Journal of cardiovascular pharmacology, 1995, Volume: 26, Issue:6

    Topics: Animals; Diterpenes; Endotoxins; Escherichia coli Infections; Ginkgolides; Hemodynamics; Lactones; Male; Peritonitis; Platelet Activating Factor; Rats; Rats, Wistar

1995
Pharmacological characterization of Sephadex-induced oedema in rat paws: predominant role of serotonin and platelet-activating factor.
    International archives of allergy and immunology, 1996, Volume: 109, Issue:4

    Topics: Animals; Bradykinin; Cyclosporine; Dexamethasone; Dextrans; Diterpenes; Edema; Ginkgolides; Histamine; Immunosuppressive Agents; Inflammation Mediators; Injections, Intravenous; Lactones; Male; Methysergide; p-Methoxy-N-methylphenethylamine; Platelet Activating Factor; Polyenes; Rats; Serotonin; Serotonin Antagonists; Sirolimus

1996
Prevention of cyclosporin nephrotoxicity with a platelet-activating factor (PAF) antagonist.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1996, Volume: 11, Issue:3

    Topics: Animals; Cyclosporine; Diterpenes; Drug Administration Routes; Ginkgolides; Glomerular Filtration Rate; Hemodynamics; Immunosuppressive Agents; Kidney; Lactones; Male; Perfusion; Plant Extracts; Platelet Activating Factor; Polyethylene Glycols; Random Allocation; Rats; Rats, Sprague-Dawley; Renal Circulation; Vasoconstriction

1996
[Ginkgolides antagonizing some effects of platelet-activating factor in vitro].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 1995, Volume: 15, Issue:10

    Topics: Animals; Anti-Asthmatic Agents; Bronchi; Diterpenes; Ginkgolides; Guinea Pigs; Lactones; Muscle Contraction; Muscle, Smooth; Platelet Activating Factor

1995
Role for intracellular platelet-activating factor in the circulatory failure in a model of gram-positive shock.
    British journal of pharmacology, 1995, Volume: 116, Issue:8

    Topics: Acute Kidney Injury; Animals; Azepines; Cells, Cultured; Diterpenes; Ginkgolides; Hemodynamics; Lactones; Lipopolysaccharides; Lung; Male; Nitric Oxide Synthase; Nitrites; Norepinephrine; Plant Extracts; Platelet Activating Factor; Rats; Rats, Wistar; Shock, Septic; Streptomyces; Teichoic Acids; Triazoles; Tumor Necrosis Factor-alpha

1995
[Effects of ginkgolide B on isobaric hypoxic pulmonary hypertension in rats].
    Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao, 1995, Volume: 26, Issue:4

    Topics: Animals; Diterpenes; Ginkgolides; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Lactones; Male; Platelet Activating Factor; Rats; Rats, Wistar

1995
[Effect of platelet activating factor receptor at spinal cord neurocyte membrane on secondary damage after spinal cord injury].
    Zhonghua yi xue za zhi, 1996, Volume: 76, Issue:2

    Topics: Animals; Cats; Cell Membrane; Diterpenes; Ginkgolides; Lactones; Male; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Spinal Cord; Spinal Cord Injuries

1996
Platelet activating factor inhibits fluid transport by corneal endothelium.
    Investigative ophthalmology & visual science, 1996, Volume: 37, Issue:9

    Topics: Animals; Cattle; Cells, Cultured; Diterpenes; Edema; Electric Conductivity; Endothelium, Corneal; Ginkgolides; Kinetics; Lactones; Platelet Activating Factor; Rabbits; Stromal Cells

1996
[Effects of platelet activating factor and platelet activating factor receptor antagonist on spinal cord blood flow after spinal cord injury].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 1995, Volume: 33, Issue:12

    Topics: Animals; Cats; Diterpenes; Female; Ginkgolides; Injections, Spinal; Lactones; Male; Platelet Activating Factor; Prostaglandins F; Regional Blood Flow; Spinal Cord; Spinal Cord Injuries; Thromboxane B2

1995
Biochemical and cellular effects of heparin-protamine injection in rabbits are partially inhibited by a PAF-acether receptor antagonist.
    European journal of pharmacology, 1996, Apr-29, Volume: 302, Issue:1-3

    Topics: Animals; Anticoagulants; Cyclooxygenase Inhibitors; Diterpenes; Fibrinolytic Agents; Ginkgolides; Heparin; Heparin Antagonists; Indomethacin; Infusions, Intravenous; Lactones; Platelet Activating Factor; Protamines; Rabbits; Thromboxane B2

1996
The role of neutrophils and platelet-activating factor in mediating experimental pancreatitis.
    Gastroenterology, 1996, Volume: 111, Issue:4

    Topics: Acute Disease; Amylases; Animals; Ceruletide; Diterpenes; Ginkgolides; Lactones; Lipase; Male; Neutrophils; Pancreatitis; Platelet Activating Factor; Rats; Rats, Sprague-Dawley

1996
Protective effect of platelet activating factor antagonists on cultured endothelial cell lysis induced by elastase or activated neutrophils.
    British journal of pharmacology, 1996, Volume: 117, Issue:5

    Topics: Azepines; Cells, Cultured; Diterpenes; Dose-Response Relationship, Drug; Endothelium, Vascular; Ginkgolides; Humans; Lactones; Leukocyte Elastase; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pyridines; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thiazoles; Triazoles

1996
Pharmacological evidence of a role for platelet activating factor as a modulator of vasomotor tone and blood pressure.
    European journal of pharmacology, 1996, Jul-25, Volume: 308, Issue:3

    Topics: Animals; Azepines; Blood Pressure; Carotid Arteries; Diterpenes; Enzyme Inhibitors; Female; Ginkgolides; Glutamic Acid; Injections, Intraventricular; Lactones; Male; Muscle Tonus; Norepinephrine; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Platelet Membrane Glycoproteins; Quinacrine; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Triazoles

1996
Cardiac ultrastructural effects of the platelet-activating factor and its antagonist BN 52021.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 1995, Volume: 47, Issue:6

    Topics: Animals; Diterpenes; Female; Fibrinolytic Agents; Ginkgolides; Guinea Pigs; Heart; Lactones; Male; Myocardium; Platelet Activating Factor

1995
Effects of intrastriatal injections of platelet-activating factor and the PAF antagonist BN 52021 on memory.
    Neurobiology of learning and memory, 1996, Volume: 66, Issue:2

    Topics: Animals; Corpus Striatum; Diterpenes; Dose-Response Relationship, Drug; Fibrinolytic Agents; Ginkgolides; Injections, Spinal; Lactones; Male; Memory; Platelet Activating Factor; Rats

1996
The platelet-activating factor antagonist BN 52021 attenuates hypoxic-ischemic brain injury in the immature rat.
    Pediatric research, 1996, Volume: 40, Issue:6

    Topics: Animals; Animals, Newborn; Brain; Cerebral Cortex; Corpus Striatum; Diterpenes; Excitatory Amino Acid Agonists; Fibrinolytic Agents; Functional Laterality; Ginkgolides; Hippocampus; Hypoxia, Brain; Ischemic Attack, Transient; Lactones; N-Methylaspartate; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Time Factors

1996
Neutrophils accentuate renal cold ischemia-reperfusion injury. Dose-dependent protective effect of a platelet-activating factor receptor antagonist.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 280, Issue:2

    Topics: Animals; Cold Temperature; Diterpenes; Fibrinolytic Agents; Ginkgolides; Glomerular Filtration Rate; Glucose; Humans; Hypertonic Solutions; In Vitro Techniques; Kidney; Lactones; Male; Neutrophils; Organ Preservation; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Renal Circulation; Reperfusion Injury; Tromethamine; Vascular Resistance

1997
Free radical enhancement promotes leucocyte recruitment through a PAF and LTB4 dependent mechanism.
    Free radical biology & medicine, 1997, Volume: 22, Issue:6

    Topics: Animals; Diterpenes; Free Radicals; Ginkgolides; Indoles; Lactones; Leukotriene B4; Lipase; Male; Neutrophils; Pancreas; Pancreatitis; Peroxidase; Platelet Activating Factor; Rats; Rats, Wistar; Superoxide Dismutase; Superoxides; Xanthine; Xanthine Oxidase; Xanthines

1997
Effects of platelet-activating factor on arteriolar and venular tone in rat trachea.
    Microvascular research, 1997, Volume: 53, Issue:1

    Topics: Analysis of Variance; Animals; Arterioles; Diterpenes; Enzyme Inhibitors; Ginkgolides; Lactones; Male; Muscle Tonus; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Trachea; Venules

1997
Role of platelet-activating factor in Chinese hamster ovary cell responses to cholera toxin.
    The Journal of clinical investigation, 1997, Apr-15, Volume: 99, Issue:8

    Topics: Alprostadil; Animals; Bucladesine; Cell Size; CHO Cells; Cholera Toxin; Cricetinae; Cyclic AMP; Cycloheximide; Dactinomycin; Dinoprostone; Diterpenes; Ginkgolides; Humans; Lactones; Phospholipases A; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Synthesis Inhibitors; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thiazoles

1997
Platelet-activating factor. A possible role in the modulation of the vasomotor tone and blood pressure.
    Advances in experimental medicine and biology, 1996, Volume: 416

    Topics: Adrenergic alpha-Agonists; Animals; Anti-Inflammatory Agents, Non-Steroidal; Azepines; Blood Pressure; Carotid Arteries; Diterpenes; Enzyme Inhibitors; Ginkgolides; Indomethacin; Lactones; Muscle Tonus; Muscle, Smooth, Vascular; Norepinephrine; Phospholipases A; Platelet Activating Factor; Platelet Aggregation Inhibitors; Quinacrine; Rabbits; Triazoles

1996
Involvement of platelet-activating factor (PAF) in glutamate neurotoxicity in rat neuronal cultures.
    Brain research, 1997, Apr-18, Volume: 754, Issue:1-2

    Topics: Animals; Cells, Cultured; Cerebral Cortex; Diterpenes; Dose-Response Relationship, Drug; Embryo, Mammalian; Fibrinolytic Agents; Fluorescent Dyes; Fura-2; Ginkgolides; Glutamic Acid; Immunoglobulin G; Lactones; Neurons; Neurotoxins; Platelet Activating Factor; Pyridinium Compounds; Rats

1997
Induction of early pregnancy factor activity in vitro by platelet-activating factor in mice.
    Journal of reproduction and fertility, 1997, Volume: 109, Issue:2

    Topics: Animals; Chaperonin 10; Culture Media, Conditioned; Culture Techniques; Diterpenes; Fallopian Tubes; Female; Ginkgolides; Immunosuppressive Agents; Lactones; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Ovary; Peptides; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pregnancy Proteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Stimulation, Chemical; Suppressor Factors, Immunologic

1997
PAF antagonists as possible inhibitors of corneal epithelial defects and ulceration.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 1997, Volume: 13, Issue:3

    Topics: Azepines; Cornea; Corneal Injuries; Diterpenes; Enzyme Activation; Epithelium; Extracellular Matrix Proteins; Fibrinolytic Agents; Ginkgolides; Lactones; Metalloendopeptidases; Phospholipid Ethers; Platelet Activating Factor; Thienopyridines; Triazoles; Urokinase-Type Plasminogen Activator; Wound Healing

1997
Clostridium difficile toxin A induces the release of neutrophil chemotactic factors from rat peritoneal macrophages: role of interleukin-1beta, tumor necrosis factor alpha, and leukotrienes.
    Infection and immunity, 1997, Volume: 65, Issue:7

    Topics: Animals; Bacterial Toxins; Chemotaxis, Leukocyte; Clostridioides difficile; Diterpenes; Enterotoxins; Female; Ginkgolides; Indomethacin; Interleukin-1; Interleukin-8; Lactones; Leukotrienes; Macrophages, Peritoneal; Male; Platelet Activating Factor; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha

1997
Effects of MTX and BN52021 on PAF-induced chemotaxis of PMNs and intraepidermal accumulation of inflammatory cells in guinea pigs.
    Chinese medical journal, 1996, Volume: 109, Issue:6

    Topics: Animals; Chemotaxis, Leukocyte; Dermatologic Agents; Diterpenes; Drugs, Chinese Herbal; Epidermis; Ginkgolides; Guinea Pigs; Inflammation; Lactones; Methotrexate; Neutrophils; Platelet Activating Factor; Random Allocation

1996
VEGF effect on vascular permeability is mediated by synthesis of platelet-activating factor.
    The American journal of physiology, 1997, Volume: 272, Issue:6 Pt 2

    Topics: Animals; Blood Proteins; Capillary Permeability; Cattle; Cells, Cultured; Chromatography, High Pressure Liquid; Diterpenes; Endothelial Growth Factors; Endothelium, Vascular; Fibrinolytic Agents; Ginkgolides; Injections, Intravenous; Lactones; Lymphokines; Mitogens; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

1997
Platelet-activating factor and antagonists modulate DNA synthesis in human bone marrow stromal cell cultures.
    Journal of lipid mediators and cell signalling, 1997, Volume: 16, Issue:3

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Blood; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Culture Media; Diterpenes; DNA Replication; Fibrinolytic Agents; Fibroblast Growth Factor 2; Ginkgolides; Humans; Lactones; Phospholipases A; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Primary Myelofibrosis; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Stromal Cells; Thymidine

1997
Involvement of phospholipase A2 in gentamicin-induced rat mesangial cell activation.
    The American journal of physiology, 1997, Volume: 273, Issue:1 Pt 2

    Topics: Acetates; Animals; Aristolochic Acids; Cell Division; Cell Survival; Cells, Cultured; Dinoprostone; Diterpenes; DNA; Enzyme Inhibitors; Gentamicins; Ginkgolides; Glomerular Mesangium; Kinetics; Lactones; Phenanthrenes; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Quinacrine; Rats; Rats, Wistar; Thymidine; Verapamil

1997
Synthesis of a new phosphoglycolipid with biological activity towards platelets.
    The international journal of biochemistry & cell biology, 1997, Volume: 29, Issue:5

    Topics: Animals; Anti-Asthmatic Agents; Blood Platelets; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Diterpenes; Fibrinolytic Agents; Ginkgolides; Glucosides; Lactones; Mass Spectrometry; Phosphatidic Acids; Plants; Platelet Activating Factor; Platelet Aggregation; Rabbits

1997
Effects of ginkgolide B on isobaric hypoxic pulmonary hypertension in rats.
    Chinese medical journal, 1996, Volume: 109, Issue:11

    Topics: Animals; Arterioles; Diterpenes; Ginkgolides; Hemodynamics; Hypertension, Pulmonary; Hypoxia; Lactones; Lung; Male; Platelet Activating Factor; Rats; Rats, Wistar

1996
Role of platelet-activating factor in hepatocellular Ca2+ alterations during hemorrhagic shock.
    The Journal of surgical research, 1997, Volume: 72, Issue:2

    Topics: Animals; Blood Pressure; Calcium; Cell Membrane; Cells, Cultured; Diterpenes; Free Radicals; Ginkgolides; Hemodynamics; Homeostasis; Lactones; Lipid Peroxidation; Liver; Male; Oxidation-Reduction; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Shock, Hemorrhagic; Thiobarbituric Acid Reactive Substances; Time Factors

1997
Elvax as a slow-release delivery agent for a platelet-activating factor receptor agonist and antagonist.
    Journal of neuroscience methods, 1997, Nov-07, Volume: 77, Issue:1

    Topics: Animals; Delayed-Action Preparations; Diterpenes; Dose-Response Relationship, Drug; Ginkgolides; Lactones; Platelet Activating Factor; Platelet Aggregation; Platelet Membrane Glycoproteins; Polyvinyls; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled

1997
Platelet-activating factor receptor stimulation disrupts neuronal migration In vitro.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1998, Jan-01, Volume: 18, Issue:1

    Topics: Animals; Anti-Asthmatic Agents; Cell Movement; Cells, Cultured; Cerebellum; Dioxolanes; Diterpenes; Ginkgolides; Lactones; Neurons; Phospholipid Ethers; Platelet Activating Factor; Rats; Rats, Sprague-Dawley

1998
The bioavailability of ginkgolides in Ginkgo biloba extracts.
    Planta medica, 1997, Volume: 63, Issue:6

    Topics: Animals; Biological Availability; Blood Platelets; Cell Membrane; Diterpenes; Female; Ginkgolides; Lactones; Male; Plant Extracts; Platelet Activating Factor; Rabbits

1997
Lung oedema induced by Tityus serrulatus scorpion venom in the rat.
    Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology, 1997, Volume: 118, Issue:2

    Topics: Animals; Aprotinin; Azepines; Capillary Permeability; Cyclooxygenase Inhibitors; Diterpenes; Drug Interactions; Fibrinolytic Agents; Ginkgolides; Hemostatics; Heparin; Hypertension; Injections, Intravenous; Lactones; Leukotrienes; Lipoxygenase Inhibitors; Lung; Male; Masoprocol; Platelet Activating Factor; Platelet Aggregation Inhibitors; Prostaglandins; Pulmonary Edema; Rats; Rats, Wistar; Scorpion Venoms; Triazoles

1997
Role of platelet-activating factor in long-term potentiation of the rat medial vestibular nuclei.
    Journal of neurophysiology, 1998, Volume: 79, Issue:6

    Topics: Animals; Diterpenes; Ginkgolides; In Vitro Techniques; Lactones; Long-Term Potentiation; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pyridinium Compounds; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Synaptic Transmission; Vestibular Nuclei

1998
Ginkgo biloba for dementia.
    The Medical letter on drugs and therapeutics, 1998, Jun-19, Volume: 40, Issue:1029

    Topics: Antioxidants; Clinical Trials as Topic; Dementia; Dementia, Multi-Infarct; Dietary Supplements; Diterpenes; Free Radical Scavengers; Ginkgolides; Hemorrhage; Humans; Lactones; Plant Extracts; Platelet Activating Factor

1998
Platelet-activating factor modulates cardiorespiratory responses in the conscious rat.
    The American journal of physiology, 1998, Volume: 275, Issue:2

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Animals; Blood Pressure; Brain Stem; Carbon Dioxide; Delayed-Action Preparations; Diterpenes; Ginkgolides; Heart Rate; Lactones; Male; Microinjections; Oxygen; Partial Pressure; Phospholipases A; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Respiration; Tidal Volume

1998
Effect of a platelet-activating factor (PAF) receptor antagonist on hyperacute xenograft rejection; evaluation in a pig kidney-human blood xenoperfusion model.
    Clinical and experimental immunology, 1998, Volume: 113, Issue:1

    Topics: Animals; Diterpenes; Fibrinolytic Agents; Fluorescent Antibody Technique, Indirect; Ginkgolides; Graft Rejection; Humans; In Vitro Techniques; Kidney; Kidney Function Tests; Kidney Transplantation; Lactones; Male; P-Selectin; Perfusion; Peroxidase; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Swine; Transplantation, Heterologous

1998
BN 52021 (a platelet activating factor-receptor antagonist) decreases alveolar macrophage-mediated lung injury in experimental extrinsic allergic alveolitis.
    Mediators of inflammation, 1998, Volume: 7, Issue:3

    Topics: Alveolitis, Extrinsic Allergic; Animals; Diterpenes; Ginkgolides; Guinea Pigs; L-Lactate Dehydrogenase; Lactones; Lung; Macrophage Activation; Macrophages, Alveolar; Male; Platelet Activating Factor

1998
A 3D-QSAR study on ginkgolides and their analogues with comparative molecular field analysis.
    Bioorganic & medicinal chemistry letters, 1998, Jun-02, Volume: 8, Issue:11

    Topics: Diterpenes; Ginkgolides; Lactones; Models, Molecular; Molecular Conformation; Platelet Activating Factor; Structure-Activity Relationship

1998
Inhibitory effect of the leaf extract of Ginkgo biloba L. on oxidative stress-induced platelet aggregation.
    Biochemistry and molecular biology international, 1998, Volume: 46, Issue:6

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Collagen; Diterpenes; Dose-Response Relationship, Drug; Drug Synergism; Ginkgo biloba; Ginkgolides; In Vitro Techniques; Iron; Kinetics; Lactones; Oxidative Stress; Plant Extracts; Plant Leaves; Plants, Medicinal; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; tert-Butylhydroperoxide; Thrombin

1998
Triflavin potentiates the antiplatelet activity of platelet activating factor receptor antagonist on activated neutrophil-induced platelet aggregation.
    European journal of pharmacology, 1999, Jan-08, Volume: 364, Issue:2-3

    Topics: Animals; Culture Media, Conditioned; Diterpenes; Dose-Response Relationship, Drug; Drug Synergism; Fibrinolytic Agents; Ginkgolides; Lactones; Neutrophils; Peptides; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Zymosan

1999
[Experimental study on antagonism of ginkgolides against effect of platelet-activating factor on lung strip of guinea pigs].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 1997, Volume: 17, Issue:8

    Topics: Animals; Diterpenes; Female; Ginkgolides; Guinea Pigs; Lactones; Lung; Male; Muscle Contraction; Muscle, Smooth; Platelet Activating Factor; Rats; Rats, Wistar; Receptors, Adrenergic, beta

1997
Synergetic protective effects of combined blockade by two kinds of autolesion mediator receptor on neurological function after cervical cord injury.
    Chinese medical journal, 1998, Volume: 111, Issue:5

    Topics: Animals; Cats; Diterpenes; Drug Synergism; Ginkgolides; Lactones; Male; Naloxone; Narcotic Antagonists; Platelet Activating Factor; Platelet Membrane Glycoproteins; Random Allocation; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Spinal Cord; Spinal Cord Injuries

1998
[The role of platelet activating factor in pathogenesis of acute pancreatitis in dogs].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 1997, Volume: 35, Issue:2

    Topics: Acute Disease; Amylases; Animals; Diterpenes; Dogs; Female; Ginkgolides; Lactones; Male; Pancreas; Pancreatitis; Platelet Activating Factor; Random Allocation; Taurocholic Acid; Trypsin

1997
Endothelium-dependent vasodilation in the isolated rabbit kidney following in vivo and in vitro ischaemia and reperfusion: effects of antagonizing platelet activating factor (PAF).
    Naunyn-Schmiedeberg's archives of pharmacology, 1999, Volume: 360, Issue:3

    Topics: Acetylcholine; Animals; Diterpenes; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Ginkgolides; In Vitro Techniques; Ischemia; Kidney; Lactones; Male; Nitroprusside; Phenylalanine; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Reperfusion Injury; Vasodilation; Vasodilator Agents

1999
Experimental therapy of a platelet-activating factor antagonist (ginkgolide B) on photochemically induced thrombotic cerebral ischaemia in tree shrews.
    Clinical and experimental pharmacology & physiology, 1999, Volume: 26, Issue:10

    Topics: Animals; Brain Edema; Brain Ischemia; Disease Models, Animal; Diterpenes; Female; Ginkgolides; Intracranial Thrombosis; Lactones; Male; Neuroprotective Agents; Platelet Activating Factor; Tupaiidae

1999
Motility induced by human immunodeficiency virus-1 Tat on Kaposi's sarcoma cells requires platelet-activating factor synthesis.
    The American journal of pathology, 1999, Volume: 155, Issue:5

    Topics: Azepines; Cell Movement; Diterpenes; Dose-Response Relationship, Drug; Fibrinolytic Agents; Gene Products, tat; Ginkgolides; HIV-1; Humans; Lactones; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Pyridinium Compounds; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Sarcoma, Kaposi; tat Gene Products, Human Immunodeficiency Virus; Triazoles; Tumor Cells, Cultured

1999
Modulation of long-term potentiation in the CA1 area of rat hippocampus by platelet-activating factor.
    Advances in experimental medicine and biology, 1999, Volume: 469

    Topics: Animals; Diterpenes; Electric Stimulation; Ginkgolides; Hippocampus; In Vitro Techniques; Lactones; Long-Term Potentiation; Male; Neurotransmitter Agents; Phospholipid Ethers; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Receptors, Cell Surface; Receptors, G-Protein-Coupled

1999
Lipid mediators stimulate reactive oxygen species formation in immortalized human keratinocytes.
    Advances in experimental medicine and biology, 1999, Volume: 469

    Topics: Calcium; Cell Line; Ceramides; Diterpenes; Ginkgolides; Humans; Keratinocytes; Lactones; Lipid Metabolism; Lipids; Luminescent Measurements; Lysophosphatidylcholines; Membrane Lipids; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pyridinium Compounds; Reactive Oxygen Species; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Signal Transduction

1999
Studies on the callus cultures of Ginkgo biloba and its metabolites-ginkgolides.
    Chinese journal of biotechnology, 1999, Volume: 15, Issue:1

    Topics: 2,4-Dichlorophenoxyacetic Acid; Chromatography, High Pressure Liquid; Diterpenes; Drugs, Chinese Herbal; Ginkgo biloba; Ginkgolides; Lactones; Plant Growth Regulators; Plants, Medicinal; Platelet Activating Factor

1999
BN 52021 decreases alveolar macrophage-mediated lung injury in experimental extrinsic allergic alveolitis.
    Mediators of inflammation, 1999, Volume: 8, Issue:3

    Topics: Alveolitis, Extrinsic Allergic; Animals; Diterpenes; Ginkgolides; Lactones; Lung; Macrophages, Alveolar; Platelet Activating Factor

1999
Effects of the platelet activating factor antagonists BN 52021 and BN 50730 on antigen-induced bronchial hyperresponsiveness and eosinophil infiltration in lung from sensitized guinea-pigs.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1993, Volume: 23, Issue:12

    Topics: Acetylcholine; Aerosols; Animals; Azepines; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Diterpenes; Eosinophilia; Ginkgo biloba; Ginkgolides; Guinea Pigs; Lactones; Leukotriene B4; Lung Diseases; Male; Molecular Structure; Ovalbumin; Plants, Medicinal; Platelet Activating Factor; Specific Pathogen-Free Organisms; Thienopyridines; Triazoles

1993
Alkyl and alkoxycarbonyl derivatives of ginkgolide B: synthesis and biological evaluation of PAF inhibitory activity.
    Bioorganic & medicinal chemistry, 2000, Volume: 8, Issue:6

    Topics: Animals; Blood Platelets; Diterpenes; Ginkgolides; Lactones; Molecular Structure; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rabbits; Spectrum Analysis

2000
The contractile action of platelet-activating factor on gallbladder smooth muscle.
    American journal of physiology. Gastrointestinal and liver physiology, 2000, Volume: 279, Issue:1

    Topics: Acetylcholine; Animals; Calcium; Calcium Channel Blockers; Diterpenes; Dose-Response Relationship, Drug; Free Radical Scavengers; Gallbladder Emptying; Ginkgolides; Guinea Pigs; In Vitro Techniques; Lactones; Muscle Contraction; Muscle, Smooth; Nifedipine; Pertussis Toxin; Platelet Activating Factor; Prostaglandins; Ryanodine; Vasodilator Agents; Virulence Factors, Bordetella

2000
Platelet activating factor (PAF) antagonists on cytokine induction of iNOS and sPLA2 in immortalized astrocytes (DITNC).
    Neurochemical research, 2000, Volume: 25, Issue:5

    Topics: Animals; Astrocytes; Azepines; Cell Line, Transformed; Cytokines; Diterpenes; Enzyme Induction; Gene Expression Regulation, Enzymologic; Ginkgolides; Group II Phospholipases A2; Interferon-gamma; Interleukin-1; Lactones; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Thienopyridines; Triazoles; Tumor Necrosis Factor-alpha

2000
Lysosomal activity of pulmonary alveolar macrophages in acute experimental pancreatitis in rats with reference to positive PAF-antagonist (BN 52021) effect.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2000, Volume: 52, Issue:2

    Topics: Acute Disease; Animals; beta-N-Acetylhexosaminidases; Bronchoalveolar Lavage Fluid; Cathepsin B; Diterpenes; Ginkgolides; Lactones; Lymphocytes; Lysosomes; Macrophages, Alveolar; Male; Neutrophils; Pancreatitis; Platelet Activating Factor; Rats; Rats, Wistar; Taurocholic Acid

2000
Role of platelet-activating factor in leukocyte-independent plasma extravasation and mast cell activation during endotoxemia.
    The Journal of surgical research, 2000, Volume: 93, Issue:2

    Topics: Animals; Blood; Capillary Permeability; Cell Adhesion; Diterpenes; Endotoxemia; Endotoxins; Ginkgolides; Hemodynamics; Lactones; Leukocytes; Macromolecular Substances; Male; Mast Cells; Platelet Activating Factor; Platelet Membrane Glycoproteins; Polysaccharides; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, G-Protein-Coupled

2000
The role of platelet-activating factor (PAF) antagonists and nitric oxide in cardiac actions of PAF. Electrophysiological and morphological study.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2000, Volume: 51, Issue:4 Pt 1

    Topics: 4-Aminopyridine; Action Potentials; Animals; Azepines; Diterpenes; Electrophysiology; Fibrinolytic Agents; Ginkgolides; Glyburide; Guinea Pigs; Heart; In Vitro Techniques; Lactones; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Platelet Activating Factor; Platelet Aggregation Inhibitors; Potassium Channel Blockers; Reperfusion Injury; Triazoles

2000
Identification of platelet-activating factor as the inflammatory lipid mediator in CCl4-metabolizing rat liver.
    Journal of lipid research, 2001, Volume: 42, Issue:4

    Topics: Animals; Carbon Tetrachloride; Cell Line; Chromatography, High Pressure Liquid; Diterpenes; Fluorescent Dyes; Free Radical Scavengers; Free Radicals; Fura-2; Ginkgolides; Humans; Inflammation; Inflammation Mediators; Lactones; Lipoproteins, LDL; Liver; Oxidation-Reduction; Phosphatidylcholines; Phospholipases A; Phospholipases A1; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Recombinant Proteins

2001
Synthesis and biological activity of amide derivatives of ginkgolide A.
    Journal of Asian natural products research, 2001, Volume: 3, Issue:3

    Topics: Amides; Animals; Catalysis; Chromatography; Diterpenes; Drugs, Chinese Herbal; Ginkgo biloba; Ginkgolides; Inhibitory Concentration 50; Lactones; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Plants, Medicinal; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Spectrophotometry, Infrared; Structure-Activity Relationship

2001
BN52021, a platelet activating factor antagonist, is a selective blocker of glycine-gated chloride channel.
    Neurochemistry international, 2002, Volume: 40, Issue:7

    Topics: Animals; Binding, Competitive; Chloride Channels; Diterpenes; Ginkgolides; Glycine; Hippocampus; In Vitro Techniques; Ion Channel Gating; Lactones; Platelet Activating Factor; Rats; Rats, Wistar; Receptors, Glycine; Strychnine

2002
Monocyte chemoattractant protein-1 and 5-lipoxygenase products recruit leukocytes in response to platelet-activating factor-like lipids in oxidized low-density lipoprotein.
    Journal of immunology (Baltimore, Md. : 1950), 2002, Apr-15, Volume: 168, Issue:8

    Topics: Animals; Arachidonate 5-Lipoxygenase; Cell Movement; Chemokine CCL2; Chemokines; Disease Models, Animal; Diterpenes; Eosinophils; Ginkgolides; Humans; Inflammation; Lactones; Leukocytes; Lipoproteins, LDL; Mice; Neutrophils; Phospholipids; Platelet Activating Factor; Pleural Effusion; Pleurisy; RNA, Messenger

2002
Effect of the platelet-activating factor antagonist BN-52021 on liver preservation (4 degrees): experimental study in isolated reperfused rat liver model.
    Transplantation proceedings, 2002, Volume: 34, Issue:1

    Topics: Acid Phosphatase; Adenosine Triphosphate; Animals; Bile; Diterpenes; Fibrinolytic Agents; Ginkgolides; Lactones; Liver; Male; Organ Preservation; Oxygen Consumption; Peroxidase; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Reperfusion; Time Factors

2002
Platelet-activating factor induces cell death in cultured astrocytes and oligodendrocytes: involvement of caspase-3.
    Glia, 2002, Volume: 38, Issue:3

    Topics: Animals; Animals, Newborn; Antigens, Differentiation; Astrocytes; Azepines; Caspase 3; Caspases; Cell Death; Cells, Cultured; Central Nervous System; Diterpenes; Dose-Response Relationship, Drug; Free Radical Scavengers; Ginkgolides; Glial Fibrillary Acidic Protein; Inflammation; Lactones; Mice; Mice, Inbred CBA; Oligodendroglia; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Spinal Cord Injuries; Triazoles

2002
Early vascular permeability in murine experimental peritonitis is co-mediated by resident peritoneal macrophages and mast cells: crucial involvement of macrophage-derived cysteinyl-leukotrienes.
    Inflammation, 2002, Volume: 26, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Capillary Leak Syndrome; Capillary Permeability; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cysteine; Diterpenes; Eicosanoids; Enzyme Induction; Ginkgolides; Histamine Release; Indoles; Indomethacin; Isoenzymes; Lactones; Leukotriene C4; Leukotrienes; Lipoxygenase Inhibitors; Macrophages, Peritoneal; Male; Mast Cells; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Mutant Strains; Nitrobenzenes; Peritonitis; Phospholipid Ethers; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Quinolines; Sulfonamides; Thioglycolates; Zymosan

2002
Ginkgolides: selective acetylations, translactonization, and biological evaluation.
    The Journal of organic chemistry, 2002, Jun-28, Volume: 67, Issue:13

    Topics: Acetates; Binding, Competitive; Catalysis; Diterpenes; Ginkgo biloba; Ginkgolides; Lactones; Ligands; Photoaffinity Labels; Platelet Activating Factor; Structure-Activity Relationship

2002
Platelet-activating factor increases prostaglandin E(2) release from astrocyte-enriched cortical cell cultures.
    Brain research, 2002, Aug-09, Volume: 946, Issue:1

    Topics: Animals; Arachidonic Acid; Astrocytes; Binding Sites; Cells, Cultured; Cerebral Cortex; Dinoprostone; Diterpenes; Drug Synergism; Female; Ginkgolides; Lactones; Osmolar Concentration; Phospholipid Ethers; Platelet Activating Factor; Pyridinium Compounds; Rats; Solvents

2002
Antiplatelet aggregation activity of diterpene alkaloids from Spiraea japonica.
    European journal of pharmacology, 2002, Aug-02, Volume: 449, Issue:1-2

    Topics: Adenosine Diphosphate; Alkaloids; Animals; Arachidonic Acid; Aspirin; Blood Platelets; Diterpenes; Female; Fibrinolytic Agents; Ginkgolides; In Vitro Techniques; Indicators and Reagents; Lactones; Male; Plant Extracts; Plant Roots; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rabbits; Spiraea

2002
Ginkgolide derivatives for photolabeling studies: preparation and pharmacological evaluation.
    Journal of medicinal chemistry, 2002, Aug-29, Volume: 45, Issue:18

    Topics: Animals; Binding, Competitive; Calcium Signaling; CHO Cells; Cricetinae; Cyclopentanes; Diterpenes; Fluorescent Dyes; Furans; Ginkgolides; Lactones; Ligands; Mice; Muscle, Skeletal; Myocardium; Photoaffinity Labels; Platelet Activating Factor; Platelet Membrane Glycoproteins; Radioligand Assay; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Structure-Activity Relationship; Terpenes

2002
Platelet-activating factor antagonists decrease the inflammatory nociceptive response in rats.
    Psychopharmacology, 2002, Volume: 163, Issue:3-4

    Topics: Animals; Azepines; Diterpenes; Dose-Response Relationship, Drug; Formaldehyde; Ginkgolides; Inflammation; Lactones; Male; Pain; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Thienopyridines; Time Factors; Triazoles

2002
Immediate and delayed VEGF-mediated NO synthesis in endothelial cells: role of PI3K, PKC and PLC pathways.
    British journal of pharmacology, 2002, Volume: 137, Issue:7

    Topics: 1-Methyl-3-isobutylxanthine; Androstadienes; Animals; Calcimycin; Calcium; Cattle; Cells, Cultured; Chelating Agents; Chromones; Cyclic GMP; Diterpenes; Dose-Response Relationship, Drug; Egtazic Acid; Endothelial Growth Factors; Endothelium, Vascular; Enzyme Inhibitors; Ginkgolides; Indoles; Intercellular Signaling Peptides and Proteins; Ionophores; Lactones; Lymphokines; Maleimides; Morpholines; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroprusside; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase C; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Serine; Signal Transduction; Time Factors; Type C Phospholipases; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Wortmannin

2002
In vitro effects of ginkgolide B combined with cyclosporin A on T-lymphocyte activation and IL-5 expression in peripheral blood mononuclear cells from asthmatic subjects.
    Transplantation proceedings, 2002, Volume: 34, Issue:7

    Topics: Adult; Asthma; Cells, Cultured; Cyclosporine; Cytokines; Diterpenes; Female; Flow Cytometry; Ginkgolides; Humans; In Vitro Techniques; Interleukin-5; Kuwait; Lactones; Leukocytes, Mononuclear; Lymphocyte Activation; Male; Phytotherapy; Platelet Activating Factor; T-Lymphocytes; Tetradecanoylphorbol Acetate

2002
Neuronal damage by secretory phospholipase A2: modulation by cytosolic phospholipase A2, platelet-activating factor, and cyclooxygenase-2 in neuronal cells in culture.
    Neuroscience letters, 2003, Feb-27, Volume: 338, Issue:2

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Animals; Arachidonic Acids; Cell Death; Cells, Cultured; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cytosol; Diterpenes; Embryo, Mammalian; Enzyme Induction; Ginkgolides; Isoenzymes; L-Lactate Dehydrogenase; Lactones; Neurons; Neurotoxins; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Platelet Membrane Glycoproteins; Prostaglandin-Endoperoxide Synthases; Rats; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Recombinant Proteins; Reptilian Proteins; Up-Regulation

2003
Preparation of 7-substituted ginkgolide derivatives: potent platelet activating factor (PAF) receptor antagonists.
    Journal of medicinal chemistry, 2003, Feb-13, Volume: 46, Issue:4

    Topics: Animals; Binding, Competitive; Diterpenes; Ginkgolides; Heterocyclic Compounds, 4 or More Rings; In Vitro Techniques; Lactones; Mice; Mice, Transgenic; Muscle, Skeletal; Myocardium; Platelet Activating Factor; Platelet Membrane Glycoproteins; Radioligand Assay; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Structure-Activity Relationship

2003
[Effect of ginkgolide B on platelet-activating factor induced activation of rat polymorphonuclear leukocytes].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2003, Volume: 38, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Adhesion; Cells, Cultured; Chemotaxis, Leukocyte; Diterpenes; Drug Interactions; Ginkgo biloba; Ginkgolides; Glucuronidase; Lactones; Male; Neutrophils; Plants, Medicinal; Platelet Activating Factor; Rats; Rats, Wistar

2003
Role of platelet activating factor in triazolobenzodiazepines-induced retrograde amnesia.
    Behavioural brain research, 2003, Jun-16, Volume: 142, Issue:1-2

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Amnesia, Anterograde; Amnesia, Retrograde; Animals; Anti-Anxiety Agents; Azepines; Diazepam; Diterpenes; Escape Reaction; Female; Flumazenil; Ginkgolides; Lactones; Learning; Male; Mice; Phospholipases A; Platelet Activating Factor; Platelet Membrane Glycoproteins; Reaction Time; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, GABA-A; Retention, Psychology; Triazolam

2003
Structure-activity studies with Ginkgo biloba extract constituents as receptor-gated chloride channel blockers and modulators.
    Pharmacopsychiatry, 2003, Volume: 36 Suppl 1

    Topics: Animals; Animals, Newborn; Cerebellum; Chloride Channels; Cyclopentanes; Diterpenes; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Interactions; Electric Conductivity; Furans; gamma-Aminobutyric Acid; Ginkgo biloba; Ginkgolides; Glycine; Hippocampus; In Vitro Techniques; Inhibitory Concentration 50; Lactones; Neurons; Patch-Clamp Techniques; Plant Extracts; Platelet Activating Factor; Pyrans; Rats; Rats, Wistar; Structure-Activity Relationship

2003
Platelet-activating factor: a previously unrecognized mediator of fever.
    The Journal of physiology, 2003, Nov-15, Volume: 553, Issue:Pt 1

    Topics: Animals; Diterpenes; Environment; Fever; Ginkgolides; Lactones; Lipopolysaccharides; Male; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Long-Evans; Receptors, G-Protein-Coupled; Serum Albumin, Bovine; Temperature

2003
Inhibition of hippocampal LTP by ginkgolide B is mediated by its blocking action on PAF rather than glycine receptors.
    Neurochemistry international, 2004, Volume: 44, Issue:3

    Topics: Animals; Diterpenes; Electric Stimulation; Electrophysiology; Excitatory Postsynaptic Potentials; Ginkgolides; Glycine Agents; Hippocampus; In Vitro Techniques; Lactones; Long-Term Potentiation; Neuronal Plasticity; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Receptors, Glycine; Strychnine

2004
Involvement of the NMDA receptor/nitric oxide signal pathway in platelet-activating factor-induced neurotoxicity.
    Neuroreport, 2004, Feb-09, Volume: 15, Issue:2

    Topics: Animals; Brain Ischemia; Cell Death; Cells, Cultured; Diterpenes; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epilepsy; Excitatory Amino Acid Antagonists; Ginkgolides; Lactones; Mice; Nerve Degeneration; Neurons; Neurotoxins; Nitric Oxide; Nitric Oxide Synthase; Platelet Activating Factor; Receptors, N-Methyl-D-Aspartate; Signal Transduction

2004
Increased hepatic platelet activating factor (PAF) and PAF receptors in carbon tetrachloride induced liver cirrhosis.
    Gut, 2004, Volume: 53, Issue:6

    Topics: Animals; Blood Pressure; Carbon Tetrachloride; Diterpenes; Ginkgolides; Lactones; Liver Cirrhosis, Experimental; Male; Platelet Activating Factor; Platelet Membrane Glycoproteins; Portal Pressure; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Stellate Ganglion

2004
Determination of specific receptor sites for platelet activating factor in bovine neutrophils.
    American journal of veterinary research, 2004, Volume: 65, Issue:5

    Topics: Animals; Azepines; Base Sequence; Blotting, Western; Cattle; Cyclooctanes; Diterpenes; DNA Primers; DNA, Complementary; Enzyme-Linked Immunosorbent Assay; Ginkgolides; HL-60 Cells; Humans; Kinetics; Lactones; Lignans; Molecular Sequence Data; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Polycyclic Compounds; Radioligand Assay; Receptors, G-Protein-Coupled; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA; Triazoles; Tritium

2004
Interplay among platelet-activating factor, oxidative stress, and group I metabotropic glutamate receptors modulates neuronal survival.
    Journal of neuroscience research, 2004, Aug-15, Volume: 77, Issue:4

    Topics: Animals; Antioxidants; Azoles; Cell Death; Cell Survival; Cells, Cultured; Diterpenes; Excitatory Amino Acid Agonists; Free Radicals; Ginkgolides; Hydrogen Peroxide; Isoindoles; L-Lactate Dehydrogenase; Lactones; Nerve Degeneration; Neurons; Neuroprotective Agents; Nitric Oxide Donors; Organoselenium Compounds; Oxidative Stress; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Receptors, Metabotropic Glutamate; Vitamin K 3

2004
Targeted disruption of PSD-93 gene reduces platelet-activating factor-induced neurotoxicity in cultured cortical neurons.
    Experimental neurology, 2004, Volume: 189, Issue:1

    Topics: Animals; Blotting, Western; Cell Count; Cell Death; Cells, Cultured; Cerebral Cortex; Cyclic GMP; Diterpenes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Fluorescent Antibody Technique; Ginkgolides; Guanylate Kinases; Intracellular Signaling Peptides and Proteins; Lactones; Membrane Proteins; Mice; Mice, Knockout; Microscopy, Confocal; Nerve Tissue Proteins; Neurons; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Platelet Activating Factor; Precipitin Tests; Propidium; Receptors, N-Methyl-D-Aspartate

2004
[Corneal epithelial wound healing is delayed by platelet activating factor treatment].
    [Zhonghua yan ke za zhi] Chinese journal of ophthalmology, 2004, Volume: 40, Issue:3

    Topics: Animals; Blotting, Northern; Cell Adhesion; Cells, Cultured; Cornea; Diterpenes; Epithelium, Corneal; Gene Expression; Ginkgolides; Hepatocyte Growth Factor; In Vitro Techniques; Lactones; Models, Animal; Platelet Activating Factor; Proto-Oncogene Proteins c-met; Rabbits; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Wound Healing

2004
Synergistic interaction of endogenous platelet-activating factor and vasopressin in generating angina in rats.
    European journal of pharmacology, 2004, Sep-13, Volume: 498, Issue:1-3

    Topics: Angina Pectoris; Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Blood Pressure; Diterpenes; Dose-Response Relationship, Drug; Drug Interactions; Electrocardiography; Epinephrine; Ginkgolides; Heart Rate; Hormone Antagonists; Injections, Intravenous; Lactones; Male; Myocardial Ischemia; Ornipressin; Phentolamine; Platelet Activating Factor; Rats; Rats, Wistar; Receptors, Vasopressin; Time Factors; Vasoconstrictor Agents; Vasopressins

2004
Anti-apoptotic actions of the platelet-activating factor acetylhydrolase I alpha2 catalytic subunit.
    The Journal of biological chemistry, 2004, Dec-10, Volume: 279, Issue:50

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Animals; Apoptosis; Base Sequence; Brain; Catalytic Domain; Diterpenes; Ginkgolides; Gliotoxin; Lactones; Mice; Mice, Inbred C57BL; Molecular Sequence Data; PC12 Cells; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Subunits; Rats; Receptors, G-Protein-Coupled; RNA Interference; RNA, Small Interfering; Signal Transduction

2004
[Effects of ginkgolide B on lipopolysaccharide-induced TNFalpha production in mouse peritoneal macrophages and NF-kappaB activation in rat pleural polymorphonuclear leukocytes].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2004, Volume: 39, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diterpenes; Female; Ginkgo biloba; Ginkgolides; Lactones; Lipopolysaccharides; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C57BL; Neutrophils; NF-kappa B; Plants, Medicinal; Platelet Activating Factor; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha

2004
Platelet-activating factor enhances the expression of nerve growth factor in normal human astrocytes under hypoxia.
    Brain research. Molecular brain research, 2005, Jan-05, Volume: 133, Issue:1

    Topics: Astrocytes; Cell Hypoxia; Cell Survival; Cells, Cultured; Deferoxamine; Diterpenes; Dose-Response Relationship, Drug; Drug Interactions; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Ginkgolides; Glial Fibrillary Acidic Protein; Humans; Iron Chelating Agents; Lactones; Nerve Growth Factors; Platelet Activating Factor; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors

2005
[Inhibitory effect of ginkgolide B on angiogenesis in chronic inflammation].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2005, Volume: 40, Issue:4

    Topics: Animals; Cell Line; Diterpenes; Female; Fibrinolytic Agents; Fibroblasts; Ginkgolides; Granuloma; Humans; Inflammation; Interleukin-1; Lactones; Mice; Mice, Inbred BALB C; Neovascularization, Pathologic; Platelet Activating Factor; RNA, Messenger; Tumor Necrosis Factor-alpha; U937 Cells

2005
Human resting CD16-, CD16+ and IL-2-, IL-12-, IL-15- or IFN-alpha-activated natural killer cells differentially respond to sphingosylphosphorylcholine, lysophosphatidylcholine and platelet-activating factor.
    European journal of immunology, 2005, Volume: 35, Issue:9

    Topics: Cell Cycle Proteins; Chemotaxis; Diterpenes; Fibrinolytic Agents; Flow Cytometry; Ginkgolides; Humans; Interferon-alpha; Interleukins; Killer Cells, Natural; Lactones; Lymphocyte Activation; Lysophosphatidylcholines; Pertussis Toxin; Phosphorylcholine; Platelet Activating Factor; Receptors, G-Protein-Coupled; Receptors, IgG; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sphingosine

2005
Induction of angiogenesis by platelet-activating factor in the rat striatum.
    Neuroreport, 2005, Sep-28, Volume: 16, Issue:14

    Topics: Animals; CD11b Antigen; Cell Count; Corpus Striatum; Diterpenes; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Ginkgolides; Glial Fibrillary Acidic Protein; Guanidines; Immunohistochemistry; Lactones; Male; Neovascularization, Physiologic; Phosphopyruvate Hydratase; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Vascular Endothelial Growth Factor A

2005
PAF antagonist BN-52021 reduces intercellular adhesion molecule-1 expression and oxidative stress in rats with reperfusion damage due to unilateral testicular torsion.
    Pediatric surgery international, 2006, Volume: 22, Issue:2

    Topics: Analysis of Variance; Animals; Diterpenes; Fibrinolytic Agents; Ginkgolides; Immunohistochemistry; Intercellular Adhesion Molecule-1; Lactones; Male; Oxidative Stress; Platelet Activating Factor; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Spermatic Cord Torsion

2006
[Influence of platelet activating factor and its antagonist on portal hypertension associated with liver cirrhosis: an experiment with rats].
    Zhonghua yi xue za zhi, 2005, Dec-14, Volume: 85, Issue:47

    Topics: Animals; Carbon Tetrachloride; Ginkgolides; Hypertension, Portal; Injections, Intravenous; Lactones; Liver; Liver Cirrhosis, Experimental; Male; Platelet Activating Factor; Platelet Membrane Glycoproteins; Random Allocation; Rats; Rats, Sprague-Dawley

2005
Effect of increased hepatic platelet activating factor and its receptor portal hypertension in CCl4-induced liver cirrhosis.
    World journal of gastroenterology, 2006, Feb-07, Volume: 12, Issue:5

    Topics: Animals; Base Sequence; Blood Pressure; Carbon Tetrachloride; Diterpenes; Ginkgolides; Hypertension, Portal; Lactones; Liver; Liver Cirrhosis; Male; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; RNA, Messenger

2006
[Role of platelet activating factor in the injury of intestinal immuno-barrier function in young rats].
    Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2006, Volume: 8, Issue:1

    Topics: Animals; Diterpenes; Ginkgolides; Immunoglobulin A, Secretory; Intestines; Lactones; Lipopolysaccharides; Platelet Activating Factor; Rats; Rats, Wistar

2006
Effect of ginkgolide B on the platelet-activating factor induced changes of chemotaxis and cytoskeleton of macrophages.
    Yao xue xue bao = Acta pharmaceutica Sinica, 2006, Volume: 41, Issue:2

    Topics: Actins; Animals; Chemotaxis, Leukocyte; Diterpenes; Ginkgo biloba; Ginkgolides; Lactones; Macrophages, Peritoneal; Mice; Mice, Inbred C57BL; Plants, Medicinal; Platelet Activating Factor

2006
[Effect of ginkgolide B on the function of rat aorta smooth cells and U937 cells stimulated by oxLDL].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2006, Volume: 41, Issue:1

    Topics: Animals; Aorta, Thoracic; Cell Proliferation; Cells, Cultured; Chemokine CCL2; Diterpenes; Dose-Response Relationship, Drug; Ginkgo biloba; Ginkgolides; Humans; I-kappa B Proteins; Interleukin-8; Lactones; Lipoproteins, LDL; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Plants, Medicinal; Platelet Activating Factor; Rats; Rats, Wistar; RNA, Messenger; Synaptotagmin I; U937 Cells

2006
Cytokine-induced monocyte adhesion to endothelial cells involves platelet-activating factor: suppression by conjugated linoleic acid.
    Biochimica et biophysica acta, 2006, Volume: 1761, Issue:7

    Topics: Cell Adhesion; Cell Communication; Cells, Cultured; Diterpenes; Endothelium, Vascular; Ginkgolides; Humans; Intercellular Adhesion Molecule-1; Interleukin-1; Lactones; Linoleic Acids, Conjugated; Monocytes; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pyridinium Compounds; Receptors, G-Protein-Coupled; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1

2006
Interaction of macrophages with apoptotic cells enhances HIV Type 1 replication through PGE2, PAF, and vitronectin receptor.
    AIDS research and human retroviruses, 2006, Volume: 22, Issue:8

    Topics: Apoptosis; Celecoxib; Cyclooxygenase Inhibitors; Dinoprostone; Diterpenes; Ginkgolides; HIV-1; Humans; In Vitro Techniques; Integrin alphaVbeta3; Lactones; Macrophages; Phagocytosis; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pyrazoles; Receptors, G-Protein-Coupled; Sulfonamides; Virus Replication

2006
Understanding the regulation mechanisms of PAF receptor by agonists and antagonists: molecular modeling and molecular dynamics simulation studies.
    Proteins, 2007, Apr-01, Volume: 67, Issue:1

    Topics: Algorithms; Amino Acid Sequence; Animals; Cattle; Computational Biology; Computer Simulation; Ginkgolides; Humans; Hydrogen Bonding; Lactones; Lipid Bilayers; Models, Biological; Models, Molecular; Molecular Sequence Data; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Structure, Secondary; Receptors, G-Protein-Coupled; Rhodopsin; Sequence Alignment; Signal Transduction

2007
Significance of platelet activating factor receptor expression in pancreatic tissues of rats with severe acute pancreatitis and effects of BN52021.
    World journal of gastroenterology, 2007, Jun-07, Volume: 13, Issue:21

    Topics: Acute Disease; Amylases; Animals; Fibrinolytic Agents; Gene Expression Regulation; Ginkgolides; Lactones; Male; Pancreatitis; Platelet Activating Factor; Platelet Membrane Glycoproteins; Random Allocation; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; RNA, Messenger

2007
Improving effect of Ginkgolide B on mitochondrial respiration of ischemic neuron after cerebral thrombosis in tree shrewa.
    Chinese medical journal, 2007, Sep-05, Volume: 120, Issue:17

    Topics: Animals; Brain Ischemia; Female; Ginkgolides; Lactones; Male; Mitochondria; Neuroprotective Agents; Oxygen Consumption; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Tupaiidae

2007
Lipopolysaccharide-induced cerebral inflammatory damage and the therapeutic effect of platelet activating factor receptor antagonist.
    Neuroscience bulletin, 2007, Volume: 23, Issue:5

    Topics: Animals; Behavior, Animal; Brain Diseases; Fibrinolytic Agents; Ginkgolides; Hippocampus; Immunohistochemistry; Inflammation; Lactones; Lipopolysaccharides; Maze Learning; Microglia; Microscopy, Electron, Transmission; Neurons; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled

2007
A cardioprotective role for platelet-activating factor through NOS-dependent S-nitrosylation.
    American journal of physiology. Heart and circulatory physiology, 2008, Volume: 294, Issue:6

    Topics: Animals; Calcium; Calcium Signaling; Cell Shape; Cyclic GMP; Disease Models, Animal; Enzyme Inhibitors; Female; Ginkgolides; Lactones; Male; Mice; Mice, Inbred C57BL; Muscle Proteins; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocytes, Cardiac; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Platelet Activating Factor; Rats; Rats, Wistar; Time Factors; Ventricular Function, Left

2008
[Effect of ginkgolide B on plasma levels of interleukin-12 and PAF in severe acute pancreatitis in rats].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2008, Volume: 24, Issue:2

    Topics: Acute Disease; Animals; Ginkgolides; Interleukin-12; Lactones; Male; Pancreatitis; Platelet Activating Factor; Rats; Rats, Wistar

2008
Role of platelet-activating factor in the pathogenesis of 5-fluorouracil-induced intestinal mucositis in mice.
    Cancer chemotherapy and pharmacology, 2011, Volume: 68, Issue:3

    Topics: Animals; Antimetabolites, Antineoplastic; Cytokines; Duodenum; Fluorouracil; Ginkgolides; Intestinal Diseases; Intestinal Mucosa; Lactones; Leukocyte Count; Leukopenia; Mice; Mice, Inbred BALB C; Mice, Knockout; Mucositis; Peroxidase; Platelet Activating Factor; Receptors, Platelet-Derived Growth Factor

2011
Noninvasive molecular imaging reveals role of PAF in leukocyte-endothelial interaction in LPS-induced ocular vascular injury.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2011, Volume: 25, Issue:4

    Topics: Animals; Azepines; Ginkgolides; Lactones; Leukocyte Rolling; Lipopolysaccharides; Male; Membrane Glycoproteins; Molecular Imaging; Platelet Activating Factor; Rats; Rats, Inbred Lew; Triazoles; Uveitis

2011
[Effect of ginkgolide B on the production of NO, IL-6 and RANTES from astrocytes].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2010, Volume: 45, Issue:9

    Topics: Animals; Astrocytes; Cell Line, Tumor; Cells, Cultured; Chemokine CCL5; Dose-Response Relationship, Drug; Ginkgolides; Glioblastoma; Humans; Interleukin-1beta; Interleukin-6; Lactones; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Nitric Oxide; Platelet Activating Factor; Rats; Rats, Wistar; RNA, Messenger

2010
[Study on the pharmacokinetics of ginkgolide B for injection in rats].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2012, Volume: 35, Issue:3

    Topics: Animals; Area Under Curve; Chromatography, High Pressure Liquid; Female; Fibrinolytic Agents; Ginkgo biloba; Ginkgolides; Injections, Intravenous; Lactones; Male; Mass Spectrometry; Platelet Activating Factor; Random Allocation; Rats; Rats, Wistar; Time Factors

2012
[Study on pharmacokinetics of ginkgolide B injection in Beagle dogs].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2012, Volume: 35, Issue:5

    Topics: Animals; Area Under Curve; Biological Availability; Chromatography, High Pressure Liquid; Dogs; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Female; Fibrinolytic Agents; Ginkgo biloba; Ginkgolides; Injections, Intravenous; Lactones; Male; Models, Animal; Platelet Activating Factor; Random Allocation; Time Factors

2012
Induction of mast-cell accumulation by promutoxin, an Arg-49 phospholipase A2.
    BioMed research international, 2013, Volume: 2013

    Topics: Animals; Bothrops; Cell Adhesion Molecules; Cyproheptadine; Ginkgolides; Histamine; Histamine Release; Inflammation; Lactones; Male; Mast Cells; Mice; Mice, Inbred BALB C; Peritoneum; Phospholipases A2; Phospholipases A2, Secretory; Platelet Activating Factor; Reptilian Proteins; Snake Venoms; Terfenadine

2013
Roles of BN52021 in platelet-activating factor pathway in inflammatory MS1 cells.
    World journal of gastroenterology, 2013, Jul-07, Volume: 19, Issue:25

    Topics: Adenylyl Cyclases; Animals; Cell Line; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelial Cells; Fibrinolytic Agents; G-Protein-Coupled Receptor Kinases; Ginkgolides; Inflammation; Islets of Langerhans; Lactones; Lipopolysaccharides; Mice; p38 Mitogen-Activated Protein Kinases; Phospholipase C beta; Phospholipases A2; Platelet Activating Factor; Protein-Tyrosine Kinases; Signal Transduction

2013
Ginkgolide B inhibits platelet release by blocking Syk and p38 MAPK phosphorylation in thrombin-stimulated platelets.
    Thrombosis research, 2014, Volume: 134, Issue:5

    Topics: Adenosine Triphosphate; Blood Platelets; CD40 Ligand; Ginkgolides; Humans; Intracellular Signaling Peptides and Proteins; Lactones; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Platelet Activating Factor; Platelet Aggregation; Protein-Tyrosine Kinases; Syk Kinase

2014
PAF receptor antagonist Ginkgolide B inhibits tumourigenesis and angiogenesis in colitis-associated cancer.
    International journal of clinical and experimental pathology, 2015, Volume: 8, Issue:1

    Topics: Animals; Azoxymethane; Carcinogenesis; Colitis; Dextran Sulfate; Female; Ginkgolides; Lactones; Mice; Neovascularization, Pathologic; Plant Extracts; Platelet Activating Factor

2015
Protective effect of high concentration of BN52021 on retinal contusion in cat eyes.
    BMC ophthalmology, 2015, May-09, Volume: 15

    Topics: Animals; Cats; Contusions; Disease Models, Animal; Electroretinography; Eye Injuries; Female; Fibrinolytic Agents; Ginkgolides; Intraocular Pressure; Lactones; Male; Nerve Fibers; Platelet Activating Factor; Retina; Retinal Diseases; Retinal Ganglion Cells; Tomography, Optical Coherence; Tonometry, Ocular

2015
Ginkgolide B Reduces the Degradation of Membrane Phospholipids to Prevent Ischemia/Reperfusion Myocardial Injury in Rats.
    Pharmacology, 2015, Volume: 96, Issue:5-6

    Topics: Animals; Cell Hypoxia; Cell Membrane; Cells, Cultured; Ginkgolides; Infusions, Intravenous; L-Lactate Dehydrogenase; Lactones; Male; Membrane Potentials; Myocardial Reperfusion Injury; Myocytes, Cardiac; Phospholipids; Platelet Activating Factor; Rats, Wistar

2015
[Effect of compatibility of ginkgolide A, ginkgolide B and ginkgolide K].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2018, Volume: 43, Issue:7

    Topics: Animals; Brain Ischemia; Ginkgolides; Lactones; Platelet Activating Factor; Platelet Aggregation; Rats; Reperfusion Injury

2018
Comparing the role of Ginkgolide B and Ginkgolide K on cultured astrocytes exposed to oxygen‑glucose deprivation.
    Molecular medicine reports, 2018, Volume: 18, Issue:5

    Topics: Animals; Antioxidants; Apoptosis; Astrocytes; Gene Expression Regulation; Ginkgo biloba; Ginkgolides; Glucose; Humans; Interleukin-10; Lactones; Mice; Nervous System Diseases; Oxygen; Phosphatidylinositol 3-Kinases; Plant Extracts; Platelet Activating Factor; Signal Transduction; Transcription Factor RelA

2018
Cigarette smoking promotes bladder cancer via increased platelet-activating factor.
    Physiological reports, 2019, Volume: 7, Issue:3

    Topics: Antineoplastic Agents, Phytogenic; Cell Adhesion; Cell Line, Tumor; Coculture Techniques; Endothelial Cells; Ginkgolides; Humans; Lactones; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Signal Transduction; Smoke; Tobacco Products; Up-Regulation; Urinary Bladder; Urinary Bladder Neoplasms; Urothelium

2019