Compounds > ginkgolide a
Page last updated: 2024-09-03

ginkgolide a and wortmannin

ginkgolide a has been researched along with wortmannin in 4 studies

Compound Research Comparison

Studies
(ginkgolide a)		Trials
(ginkgolide a)		Recent Studies (post-2010)
(ginkgolide a)		Studies
(wortmannin)		Trials
(wortmannin)		Recent Studies (post-2010) (wortmannin)
762424,0662726

Protein Interaction Comparison

ProteinTaxonomyginkgolide a (IC50)wortmannin (IC50)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformHomo sapiens (human)0.0465
Myosin light chain kinase, smooth muscleGallus gallus (chicken)0.26
Metabotropic glutamate receptor 1Rattus norvegicus (Norway rat)0.0085
Phosphatidylinositol 3-kinase regulatory subunit alphaHomo sapiens (human)0.2368
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformHomo sapiens (human)0.1309
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoformHomo sapiens (human)0.0493
Serine/threonine-protein kinase mTORHomo sapiens (human)0.04
Phosphatidylinositol 4-kinase alphaHomo sapiens (human)0.28
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Homo sapiens (human)0.0492
Serine/threonine-protein kinase PLK1Homo sapiens (human)0.4433
Myosin light chain kinase, smooth muscleHomo sapiens (human)2.3567
Phosphoinositide 3-kinase regulatory subunit 5Homo sapiens (human)0.019
Serine/threonine-protein kinase PLK3Homo sapiens (human)0.1057
Phosphatidylinositol 4-kinase betaHomo sapiens (human)0.44

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Slomiany, A; Slomiany, BL4

Other Studies

4 other study(ies) available for ginkgolide a and wortmannin

ArticleYear
Platelet-activating factor mediates Helicobacter pylori lipopolysaccharide interference with gastric mucin synthesis.
    IUBMB life, 2004, Volume: 56, Issue:1

    Topics: Amidines; Androstadienes; Animals; Benzylamines; Enzyme Inhibitors; Gastric Mucins; Gastric Mucosa; Gastritis; Ginkgolides; Helicobacter Infections; Helicobacter pylori; In Vitro Techniques; Lactones; Lipopolysaccharides; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Phosphoinositide-3 Kinase Inhibitors; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Wortmannin

2004
Platelet-activating factor mediates Porphyromonas gingivalis lipopolysaccharide interference with salivary mucin synthesis via phosphatidylinositol 3-kinase-dependent constitutive nitric-oxide synthase activation.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2004, Volume: 55, Issue:1 Pt 1

    Topics: Amidines; Androstadienes; Animals; Apoptosis; Benzylamines; Cell Survival; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Ginkgolides; Glucosamine; Lactones; Lipopolysaccharides; Mucins; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Platelet Activating Factor; Porphyromonas gingivalis; Rats; Rats, Sprague-Dawley; Saliva; Salivary Glands; Sublingual Gland; Tritium; Tumor Necrosis Factor-alpha; Up-Regulation; Wortmannin

2004
Cytosolic phospholipase A2 activation in Helicobacter pylori lipopolysaccharide-induced interference with gastric mucin synthesis.
    IUBMB life, 2006, Volume: 58, Issue:4

    Topics: Androstadienes; Animals; Arachidonic Acids; Endothelin-1; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Gastric Mucosa; Ginkgolides; Lactones; Lipopolysaccharides; Models, Biological; Mucins; Organophosphonates; Phosphatidylcholines; Phosphoinositide-3 Kinase Inhibitors; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Wortmannin

2006
Interference by leptin with Helicobacter pylori lipopolysaccharide-induced cytosolic phospholipase A2 activation in gastric mucosal cells.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2007, Volume: 58, Issue:1

    Topics: Androstadienes; Animals; Apoptosis; Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Gastric Mucins; Gastric Mucosa; Ginkgolides; Lactones; Leptin; Lipopolysaccharides; Organophosphonates; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Signal Transduction; Wortmannin

2007