Page last updated: 2024-09-03

ginkgolide a and bilobalide

ginkgolide a has been researched along with bilobalide in 16 studies

Compound Research Comparison

Studies
(ginkgolide a)
Trials
(ginkgolide a)
Recent Studies (post-2010)
(ginkgolide a)
Studies
(bilobalide)
Trials
(bilobalide)
Recent Studies (post-2010) (bilobalide)
76242165559

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's9 (56.25)29.6817
2010's6 (37.50)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
Chan, VW; Cheung, F; O, K; Siow, YL; Woo, CW1
Kuribara, H; Maruyama, Y; Weintraub, ST; Yoshihama, T1
Chiu, HL; Lin, HY; Yang, TC1
Jaracz, S; Malik, S; Nakanishi, K1
Chang, TK; Chen, J; Teng, XW1
Wang, DP; Yuan, M; Zhang, XQ; Zhou, X1
Berova, N; Dzyuba, SV; He, J; Nakanishi, K; Petrovic, AG; Polavarapu, PL1
Ding, C; Ge, Q; Xie, J; Zhi, X; Zhou, Z1
Bi, HC; Chen, X; Deng, Y; Ding, L; He, F; Huang, M; Huang, ZY; Liu, YQ; Ou, ZM; Yu, JJ; Zhao, LZ; Zhou, SF1
Bauer, R; Beubler, E; Dittrich, P; Feizlmayr, E; Pinl, F; Suter, A; Woelkart, K1
Guo, W; Liu, CH; Maerz, S; Zhu, YZ1
Chen, SN; Lankin, DC; Napolitano, JG; Pauli, GF1
Gu, X; Liu, F; Wang, Y; Yan, C; Zhao, H1
Chen, Y; Kang, Q; Lan, Y; Li, H; Liu, N; Ma, Q; Wang, W; Wu, Q; Zhang, Q; Zhang, Y; Zhao, B1
Geng, T; Si, HH; Sun, XP; Xue, J; Zhao, J1
Akca, M; Gedikli, Ö; Yildirim, M1

Trials

1 trial(s) available for ginkgolide a and bilobalide

ArticleYear
Pharmacokinetics of bilobalide, ginkgolide A and B after administration of three different Ginkgo biloba L. preparations in humans.
    Phytotherapy research : PTR, 2010, Volume: 24, Issue:3

    Topics: Adult; Biological Availability; Cardiovascular Agents; Chromatography, High Pressure Liquid; Cyclopentanes; Female; Furans; Ginkgo biloba; Ginkgolides; Humans; Lactones; Male; Mass Spectrometry; Phytotherapy; Plant Extracts; Tablets; Young Adult

2010

Other Studies

15 other study(ies) available for ginkgolide a and bilobalide

ArticleYear
Homocysteine stimulates inducible nitric oxide synthase expression in macrophages: antagonizing effect of ginkgolides and bilobalide.
    Molecular and cellular biochemistry, 2003, Volume: 243, Issue:1-2

    Topics: Antioxidants; Cell Line; Cyclopentanes; Diterpenes; Dose-Response Relationship, Drug; Furans; Ginkgolides; Homocysteine; Humans; Lactones; Macrophages; Models, Biological; Monocytes; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; RNA, Messenger; Superoxides; Time Factors

2003
An anxiolytic-like effect of Ginkgo biloba extract and its constituent, ginkgolide-A, in mice.
    Journal of natural products, 2003, Volume: 66, Issue:10

    Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Benzodiazepines; Caffeine; Cyclopentanes; Diazepam; Diterpenes; Dose-Response Relationship, Drug; Furans; Ginkgo biloba; Ginkgolides; Lactones; Male; Maze Learning; Mice; Mice, Inbred Strains; Molecular Structure; Motor Activity; Phenobarbital; Plant Extracts; Plants, Medicinal; Sleep

2003
Determination of ginkgolide A, B, and bilobalide in biloba L. extracts by microdialysis-HPLC.
    Analytical and bioanalytical chemistry, 2004, Volume: 379, Issue:3

    Topics: Calibration; Chromatography, High Pressure Liquid; Cyclopentanes; Diterpenes; Furans; Ginkgo biloba; Ginkgolides; Lactones; Microdialysis; Plant Extracts; Plant Leaves

2004
Isolation of ginkgolides A, B, C, J and bilobalide from G. biloba extracts.
    Phytochemistry, 2004, Volume: 65, Issue:21

    Topics: Cyclopentanes; Diterpenes; Furans; Ginkgo biloba; Ginkgolides; Lactones; Molecular Structure; Plant Extracts

2004
Distinct role of bilobalide and ginkgolide A in the modulation of rat CYP2B1 and CYP3A23 gene expression by Ginkgo biloba extract in cultured hepatocytes.
    Drug metabolism and disposition: the biological fate of chemicals, 2006, Volume: 34, Issue:2

    Topics: Animals; Cells, Cultured; Cyclopentanes; Cytochrome P-450 Enzyme System; Diterpenes; Furans; Gene Expression Regulation, Enzymologic; Ginkgo biloba; Ginkgolides; Hepatocytes; Lactones; Male; Plant Extracts; Rats; Rats, Sprague-Dawley; RNA, Messenger; Testosterone

2006
[Quantitative determination of ginkgolides by liquid chromatography-electrospray mass spectrometry].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2005, Volume: 30, Issue:24

    Topics: Chromatography, Liquid; Cyclopentanes; Drugs, Chinese Herbal; Furans; Ginkgo biloba; Ginkgolides; Lactones; Plant Leaves; Plants, Medicinal; Spectrometry, Mass, Electrospray Ionization; Tablets

2005
Spectroscopic investigation of Ginkgo biloba terpene trilactones and their interaction with amyloid peptide Abeta(25-35).
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2008, Volume: 69, Issue:4

    Topics: Amyloid beta-Peptides; Circular Dichroism; Cyclopentanes; Furans; Ginkgo biloba; Ginkgolides; Lactones; Peptides; Spectrophotometry, Infrared; Terpenes; Time Factors; Vibration

2008
Simultaneous determination of ginkgolides A, B, C and bilobalide in plasma by LC-MS/MS and its application to the pharmacokinetic study of Ginkgo biloba extract in rats.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2008, Mar-15, Volume: 864, Issue:1-2

    Topics: Animals; Chromatography, High Pressure Liquid; Cyclopentanes; Female; Furans; Ginkgo biloba; Ginkgolides; Lactones; Male; Plant Extracts; Quality Control; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry

2008
Induction of cytochrome P450s by terpene trilactones and flavonoids of the Ginkgo biloba extract EGb 761 in rats.
    Xenobiotica; the fate of foreign compounds in biological systems, 2008, Volume: 38, Issue:5

    Topics: Animals; Cyclopentanes; Cytochrome P-450 Enzyme System; Enzyme Induction; Flavonoids; Furans; Gene Expression; Ginkgo biloba; Ginkgolides; Kaempferols; Lactones; Male; Microsomes, Liver; Plant Extracts; Quercetin; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2008
Anti-ischaemic effects of bilobalide on neonatal rat cardiomyocytes and the involvement of the platelet-activating factor receptor.
    Bioscience reports, 2011, Volume: 31, Issue:5

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Animals; Animals, Newborn; Cardiotonic Agents; Cell Hypoxia; Cell Survival; Cells, Cultured; Cyclopentanes; Furans; Gene Expression; Ginkgolides; Lactones; Male; Myocardial Ischemia; Myocardium; Myocytes, Cardiac; Platelet Membrane Glycoproteins; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled

2011
Complete 1H NMR spectral analysis of ten chemical markers of Ginkgo biloba.
    Magnetic resonance in chemistry : MRC, 2012, Volume: 50, Issue:8

    Topics: Cyclopentanes; Furans; Ginkgo biloba; Ginkgolides; Kaempferols; Lactones; Magnetic Resonance Spectroscopy; Molecular Structure; Protons; Quercetin; Reference Standards; Rutin; Stereoisomerism

2012
[Microfluidic evaporative light scattering detector coupled with capillary liquid chromatography and its application to Ginkgo biloba extract analysis].
    Se pu = Chinese journal of chromatography, 2013, Volume: 31, Issue:8

    Topics: Chromatography, High Pressure Liquid; Cyclopentanes; Drugs, Chinese Herbal; Furans; Ginkgo biloba; Ginkgolides; Lactones; Microfluidics; Plant Extracts; Scattering, Radiation; Terpenes

2013
Enhanced dissolution rate and oral bioavailability of Ginkgo biloba extract by preparing solid dispersion via hot-melt extrusion.
    Fitoterapia, 2015, Volume: 102

    Topics: Animals; Biological Availability; Cyclopentanes; Furans; Ginkgo biloba; Ginkgolides; Kaempferols; Lactones; Male; Molecular Structure; Plant Extracts; Quercetin; Rats, Sprague-Dawley; Solubility

2015
[Absolute bioavailability of ginkgolide compounds in rats].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2015, Volume: 40, Issue:14

    Topics: Animals; Biological Availability; Chromatography, High Pressure Liquid; Cyclopentanes; Furans; Ginkgolides; Lactones; Male; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry

2015
Investigating the mechanism of action of ginkgolides and bilobalide on absence seizures in male WAG/Rij rats.
    Journal of neuroscience research, 2023, Volume: 101, Issue:6

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bilobalides; Disease Models, Animal; Dizocilpine Maleate; Electroencephalography; Epilepsy, Absence; Excitatory Amino Acid Antagonists; Ginkgolides; Male; Nicardipine; Rats; Seizures

2023