Page last updated: 2024-09-03

ginkgolide a and 1-hexadecyl-2-acetyl-glycero-3-phosphocholine

ginkgolide a has been researched along with 1-hexadecyl-2-acetyl-glycero-3-phosphocholine in 12 studies

Compound Research Comparison

Studies
(ginkgolide a)
Trials
(ginkgolide a)
Recent Studies (post-2010)
(ginkgolide a)
Studies
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Trials
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Recent Studies (post-2010) (1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
762429,156187552

Protein Interaction Comparison

ProteinTaxonomyginkgolide a (IC50)1-hexadecyl-2-acetyl-glycero-3-phosphocholine (IC50)
Platelet-activating factor receptorHomo sapiens (human)0.0003

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (8.33)18.2507
2000's9 (75.00)29.6817
2010's1 (8.33)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Ferreira, MG; Fonteles, MC1
Slomiany, A; Slomiany, BL6
Burgos, RA; Folch, H; Hancke, JL; Hermosilla, R; Hidalgo, MA; Matthei, SM1
Bolsover, S; Ranasinghe, S1
Basilico, F; Bombardelli, E; De Palma, A; Mauri, P; Morazzoni, P; Pozzi, F; Riva, A; Rossoni, G1
Cao, L; Cao, ZY; Luo, YP; Wang, ZZ; Xiao, W; Zhang, H; Zhang, XZ1
Abdulwanis Mohamed, Z; Faizal Abdull Razis, A; Hossain, R; Islam, MT; Jamaddar, S; Martorell, M; Mondal, M; Pastene-Navarrete, E; Quispe, C; Ray, P; Salehi, B; Sani Jaafaru, M; Sarkar, C; Sharifi-Rad, J1

Reviews

1 review(s) available for ginkgolide a and 1-hexadecyl-2-acetyl-glycero-3-phosphocholine

ArticleYear
Therapeutic promises of ginkgolide A: A literature-based review.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020, Volume: 132

    Topics: Animals; Anti-Anxiety Agents; Anti-Inflammatory Agents; Antineoplastic Agents, Phytogenic; Ginkgo biloba; Ginkgolides; Humans; Lactones; Plant Leaves; Platelet Activating Factor

2020

Trials

1 trial(s) available for ginkgolide a and 1-hexadecyl-2-acetyl-glycero-3-phosphocholine

ArticleYear
LC-MS characterization of terpene lactones in plasma of experimental animals treated with Ginkgo biloba extracts Correlation with pharmacological activity.
    Journal of pharmaceutical and biomedical analysis, 2006, Feb-24, Volume: 40, Issue:3

    Topics: Adult; Animals; Biological Availability; Bronchoconstriction; Chromatography, Liquid; Diterpenes; Ginkgo biloba; Ginkgolides; Guinea Pigs; Histamine; Humans; Lactones; Male; Mass Spectrometry; Models, Molecular; Molecular Conformation; Ovalbumin; Plant Extracts; Platelet Activating Factor; Terpenes; Thromboxane B2

2006

Other Studies

10 other study(ies) available for ginkgolide a and 1-hexadecyl-2-acetyl-glycero-3-phosphocholine

ArticleYear
Different classes of PAF-antagonists block norepinephrine-induced vascular escape and tachyphylaxis in the isolated rabbit kidney.
    Research communications in molecular pathology and pharmacology, 1996, Volume: 94, Issue:2

    Topics: Animals; Azepines; Dihydropyridines; Ginkgolides; In Vitro Techniques; Kidney; Lactones; Norepinephrine; Platelet Activating Factor; Rabbits; Tachyphylaxis; Triazoles; Vasoconstriction

1996
Platelet-activating factor modulates gastric mucosal inflammatory responses to Helicobacter pylori lipopolysaccharide.
    Biochemical and biophysical research communications, 2003, Jun-20, Volume: 306, Issue:1

    Topics: Animals; Apoptosis; Cyclooxygenase 2; Gastric Mucosa; Gastritis; Ginkgolides; Helicobacter Infections; Helicobacter pylori; Inflammation Mediators; Isoenzymes; Lactones; Lipopolysaccharides; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha

2003
Biphasic role of platelet-activating factor in oral mucosal ulcer healing.
    IUBMB life, 2003, Volume: 55, Issue:8

    Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Blotting, Western; Cyclooxygenase 2; Disease Progression; Ginkgolides; Isoenzymes; Lactones; Mouth Mucosa; Mucous Membrane; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Time Factors; Tumor Necrosis Factor-alpha; Ulcer

2003
Platelet-activating factor mediates Helicobacter pylori lipopolysaccharide interference with gastric mucin synthesis.
    IUBMB life, 2004, Volume: 56, Issue:1

    Topics: Amidines; Androstadienes; Animals; Benzylamines; Enzyme Inhibitors; Gastric Mucins; Gastric Mucosa; Gastritis; Ginkgolides; Helicobacter Infections; Helicobacter pylori; In Vitro Techniques; Lactones; Lipopolysaccharides; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Phosphoinositide-3 Kinase Inhibitors; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Wortmannin

2004
Platelet-activating factor mediates Porphyromonas gingivalis lipopolysaccharide interference with salivary mucin synthesis via phosphatidylinositol 3-kinase-dependent constitutive nitric-oxide synthase activation.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2004, Volume: 55, Issue:1 Pt 1

    Topics: Amidines; Androstadienes; Animals; Apoptosis; Benzylamines; Cell Survival; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Ginkgolides; Glucosamine; Lactones; Lipopolysaccharides; Mucins; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Platelet Activating Factor; Porphyromonas gingivalis; Rats; Rats, Sprague-Dawley; Saliva; Salivary Glands; Sublingual Gland; Tritium; Tumor Necrosis Factor-alpha; Up-Regulation; Wortmannin

2004
Determination of specific receptor sites for platelet activating factor in bovine neutrophils.
    American journal of veterinary research, 2004, Volume: 65, Issue:5

    Topics: Animals; Azepines; Base Sequence; Blotting, Western; Cattle; Cyclooctanes; Diterpenes; DNA Primers; DNA, Complementary; Enzyme-Linked Immunosorbent Assay; Ginkgolides; HL-60 Cells; Humans; Kinetics; Lactones; Lignans; Molecular Sequence Data; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Polycyclic Compounds; Radioligand Assay; Receptors, G-Protein-Coupled; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA; Triazoles; Tritium

2004
Microglial calcium responses to platelet-activating factor are inhibited by analogue CAS 99103-16-9 and dihydropyridine PCA 4248 but not by ginkgolide A.
    Basic & clinical pharmacology & toxicology, 2004, Volume: 95, Issue:2

    Topics: Aniline Compounds; Calcium; Calcium Signaling; Cell Line; Dihydropyridines; Diterpenes; Ginkgolides; Glyceryl Ethers; Humans; Lactones; Microglia; Platelet Activating Factor; United Kingdom; Xanthenes

2004
Cytosolic phospholipase A2 activation in Helicobacter pylori lipopolysaccharide-induced interference with gastric mucin synthesis.
    IUBMB life, 2006, Volume: 58, Issue:4

    Topics: Androstadienes; Animals; Arachidonic Acids; Endothelin-1; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Gastric Mucosa; Ginkgolides; Lactones; Lipopolysaccharides; Models, Biological; Mucins; Organophosphonates; Phosphatidylcholines; Phosphoinositide-3 Kinase Inhibitors; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Wortmannin

2006
Interference by leptin with Helicobacter pylori lipopolysaccharide-induced cytosolic phospholipase A2 activation in gastric mucosal cells.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2007, Volume: 58, Issue:1

    Topics: Androstadienes; Animals; Apoptosis; Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Gastric Mucins; Gastric Mucosa; Ginkgolides; Lactones; Leptin; Lipopolysaccharides; Organophosphonates; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Signal Transduction; Wortmannin

2007
[Effect of compatibility of ginkgolide A, ginkgolide B and ginkgolide K].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2018, Volume: 43, Issue:7

    Topics: Animals; Brain Ischemia; Ginkgolides; Lactones; Platelet Activating Factor; Platelet Aggregation; Rats; Reperfusion Injury

2018